WEBVTT 00:00:01.000 --> 00:00:05.000 This free program is paid for by the listeners of Redwood Community Radio. 00:00:05.000 --> 00:00:09.000 If you're not already a member, please think of joining us. Thank you. 00:00:09.000 --> 00:00:16.000 40... 48 degrees outside our Redway studios. 00:00:16.000 --> 00:00:26.000 We are at KMUD 91.1 FM, KMUE 88.1 FM, NKLAI, Leightonville 90.3 FM. 00:00:26.000 --> 00:00:33.000 Our Eureka and Garberville signals are also on HD. 00:00:33.000 --> 00:00:41.000 And we have FM translator K258BQ in Shelter Cove at 99.5. 00:00:41.000 --> 00:00:50.000 The views and opinions expressed throughout the broadcast day are those of the speakers and not necessarily those of the station, its staff, or underwriters. 00:00:50.000 --> 00:00:55.000 Time will be made available for other viewpoints. Thank you for joining us. 00:00:56.000 --> 00:01:02.000 And KMUD thanks Jessica Baker of Jade Dragon Acupuncture for her support of Redwood Community Radio. 00:01:02.000 --> 00:01:08.000 Practicing traditional Chinese medicine, Jessica treats conditions ranging from psoriasis to post-traumatic stress. 00:01:08.000 --> 00:01:22.000 Located at 607 F Street in Arcata, Jade Dragon Acupuncture can be reached at 822-4300 and online at jadedragonacupuncture.com. 00:01:23.000 --> 00:01:26.000 Get ready for Ask Your Herb Doctor. 00:01:27.000 --> 00:01:38.000 [Music] 00:01:39.000 --> 00:01:48.000 [Music] 00:01:48.000 --> 00:01:58.000 [Music] 00:01:58.000 --> 00:02:08.000 [Music] 00:02:08.000 --> 00:02:22.000 [Music] 00:02:22.000 --> 00:02:26.000 Welcome to this month's Ask Your Herb Doctor. My name is Andrew Murray. 00:02:26.000 --> 00:02:32.000 For those of you who perhaps have never listened to the shows which run every third Friday of the month from 7 to 8pm, 00:02:32.000 --> 00:02:38.000 my wife and I are both licensed medical herbalists who trained in England and graduated there with a degree in herbal medicine. 00:02:38.000 --> 00:02:46.000 We run a clinic in Garboville where we consult with clients about a wide range of conditions and recommend herbal medicine and dietary advice. 00:02:46.000 --> 00:02:52.000 So you're listening to Ask Your Herb Doctor on KMUD Garboville 91.1 FM and from 7.30. 00:02:52.000 --> 00:02:57.000 In fact, what we'll do is I think this time round we'll just open up the lines straight off the bat. 00:02:57.000 --> 00:03:02.000 We normally open them up from 7.30 to 8 but people are welcome to call in any time. 00:03:02.000 --> 00:03:09.000 So how about that? Let's see what that does to the show's train of thought. 00:03:09.000 --> 00:03:11.000 Anyway, okay, so the end of the show is at 8 o'clock. 00:03:11.000 --> 00:03:19.000 You're all invited to call in with questions either related or unrelated to this month's subject of aging and energy reversal. 00:03:19.000 --> 00:03:29.000 The number here if you live in the area is 923 3911 or if you live outside the area the toll free number is 1800 KMUD RAD. 00:03:29.000 --> 00:03:39.000 Well, this month we had a small amount to finish up from last month's show on misdiagnosis of thyroid conditions 00:03:39.000 --> 00:03:47.000 but something that came into the limelight if you like and I know it's been looked at for quite a while now 00:03:47.000 --> 00:03:54.000 and I know Dr. Peat who will be joining us in a moment here has spent a long time researching in his own academic career 00:03:54.000 --> 00:03:57.000 and that's the aging process. 00:03:57.000 --> 00:04:07.000 Well, as it is I generally take a look at the news most every day and I look at the BBC news out of kind of a preference I suppose 00:04:07.000 --> 00:04:12.000 and I saw an article in the health section of the BBC news 00:04:12.000 --> 00:04:20.000 and the title was US scientists have performed a dramatic reversal of the aging process in animal studies 00:04:20.000 --> 00:04:28.000 and this is what I want to bring out with Dr. Peat's history using things like progesterone and thyroid 00:04:28.000 --> 00:04:38.000 which are definitely anti-aging in their own right and energy creative and energy reserving products. 00:04:38.000 --> 00:04:44.000 So anyway, I just want to quickly read the article out and then introduce Dr. Peat onto the show for those people 00:04:44.000 --> 00:04:46.000 who perhaps have never heard of him before. 00:04:46.000 --> 00:04:51.000 So the article said that they used a chemical to rejuvenate the muscles in mice 00:04:51.000 --> 00:04:56.000 and said it was the equivalent of transforming a 60 year old's muscle to that of a 20 year old 00:04:56.000 --> 00:05:01.000 but they did put in parentheses here but muscle strength did not improve. 00:05:01.000 --> 00:05:05.000 So just the general quality of the muscle or the health, I think it's more appropriate, 00:05:05.000 --> 00:05:10.000 or the energy readiness of the muscle became that of a 20 year old's. 00:05:10.000 --> 00:05:17.000 So their study in the journal Cell identified an entirely new mechanism of aging and then reversed it. 00:05:17.000 --> 00:05:22.000 Other researchers said it was an exciting finding and aging is considered a one-way street 00:05:22.000 --> 00:05:28.000 but now researchers at Harvard Medical School have shown that some aspects can be reversed. 00:05:28.000 --> 00:05:34.000 Their research focused on a chemical called NAD, nicotinamide adenine dinucleotide 00:05:34.000 --> 00:05:40.000 and its levels naturally drop off in the cell of the body with age. 00:05:40.000 --> 00:05:45.000 The team showed that this disrupted the function of the cells in built power stations and mitochondria 00:05:45.000 --> 00:05:50.000 leading to lower energy production and aging as a result. 00:05:50.000 --> 00:05:56.000 Experiments showed that boosting NAD levels by giving mice a chemical which they naturally convert into NAD 00:05:56.000 --> 00:05:58.000 could reverse the sands of time. 00:05:58.000 --> 00:06:04.000 One week of youth medication in two year old mice meant their muscles became akin to those of a six month old 00:06:04.000 --> 00:06:11.000 in terms of mitochondrial function, muscle wastage, inflammation and insulin resistance, so greatly improved. 00:06:11.000 --> 00:06:15.000 And Dr. Anna Gomes from the Department of Genetics at Harvard Medical School said, 00:06:15.000 --> 00:06:17.000 "We believe this is quite an important finding." 00:06:17.000 --> 00:06:23.000 She argues that muscle strength may return with a longer course of treatment, so is this a cure? 00:06:23.000 --> 00:06:27.000 Well, thanks so much for joining us this month again, Dr. Peat. 00:06:27.000 --> 00:06:33.000 For those people who have just tuned into the show or maybe have never heard you before 00:06:33.000 --> 00:06:37.000 and they have quite a following and I think those people kind of generally tune into the show, 00:06:37.000 --> 00:06:44.000 but would you just give people that may be new listeners an outline of your academic and professional background? 00:06:44.000 --> 00:06:52.000 In the 60s, I had been working in linguistics, but on my own studying, 00:06:52.000 --> 00:07:00.000 I was very interested in general questions of aging and the brain in particular 00:07:00.000 --> 00:07:05.000 and how the brain makes consciousness and language possible 00:07:05.000 --> 00:07:13.000 and how that changes during maturation and aging. 00:07:13.000 --> 00:07:20.000 So I enrolled at the University of Oregon thinking I would study brain biology in 1968 00:07:20.000 --> 00:07:27.000 and found that the brain biology people were extremely dogmatic, 00:07:27.000 --> 00:07:39.000 thinking in terms only of genetic control, membrane functions and nothing much in between. 00:07:39.000 --> 00:07:47.000 And I looked around the department and found that the reproductive biologists seemed to be more scientific 00:07:47.000 --> 00:07:56.000 and actually looking for an explanation rather than trying to explain things in terms of what they believed they knew. 00:07:56.000 --> 00:08:06.000 So I worked on reproductive aging and our lab specialized in the female aging. 00:08:06.000 --> 00:08:17.000 And I concentrated on the energy, oxidative metabolism and the changes occurring in the uterus with aging. 00:08:17.000 --> 00:08:28.000 And I found that all kinds of stress converge with the changes that you see during aging, 00:08:28.000 --> 00:08:30.000 especially in the reproductive system. 00:08:30.000 --> 00:08:42.000 It was like the lining of the uterus was a very good model for things that happen in the brain and the whole organism. 00:08:42.000 --> 00:08:54.000 And all types of stress from radiation to a bad diet, vitamin E deficiency, 00:08:54.000 --> 00:09:03.000 deficiency of oxygen, all of these things mimic the changes that you see in aging. 00:09:03.000 --> 00:09:10.000 And basically that's the area that I've been thinking about a lot ever since. 00:09:10.000 --> 00:09:12.000 Okay, good. 00:09:12.000 --> 00:09:19.000 I think some of the language sometimes is a little difficult for general listeners to get their heads around 00:09:19.000 --> 00:09:24.000 if they're not medically or physiology minded or trained. 00:09:24.000 --> 00:09:36.000 And so I think just to open up the subject this evening of aging in light of the research that was broadcast in an article produced by Harvard. 00:09:36.000 --> 00:09:47.000 If we want to talk about the two types of interactions that happen in the aging process that this was looking at 00:09:47.000 --> 00:09:57.000 in terms of the interaction with DNA, with methylation as a additive process which degrades the DNA, 00:09:57.000 --> 00:10:07.000 and the acetylation, which apparently is more protective, they talk about an epigenetic modification. 00:10:07.000 --> 00:10:19.000 And perhaps if you -- we mentioned in the past that, you know, unlike most modern thinking that would tell us that we are a result of our genetics 00:10:19.000 --> 00:10:26.000 and there's nothing much we can do about it, I know that you found many different research articles that have proved beyond doubt 00:10:26.000 --> 00:10:30.000 that there very much is something that can be done. 00:10:30.000 --> 00:10:40.000 And the environment in its own right has its own effects on the genes, even at a very local and a very time-dependent manner. 00:10:40.000 --> 00:10:46.000 So it's not a case of the genes being fixed in time and space and immutable, 00:10:46.000 --> 00:10:50.000 but that definitely changes can be done in a relatively short space of time. 00:10:50.000 --> 00:10:59.000 So when the articles talk about epigenetic modification involved in gene expression, for example, 00:10:59.000 --> 00:11:11.000 to perhaps stave off cancer or even allow the cancer to exist, would you explain what that is, that epigenetic modification? 00:11:11.000 --> 00:11:20.000 Well, Luther Burbank was a person who explored the influence of the environment. 00:11:20.000 --> 00:11:31.000 Many biologists from the time of Lamarck down through Barbara McClintock, who was ignored until just about 20 years ago, 00:11:31.000 --> 00:11:36.000 they sort of pulled her out of obscurity before she died. 00:11:36.000 --> 00:11:46.000 And these people had demonstrated that the need for a function could elicit the function in an organism 00:11:46.000 --> 00:11:53.000 so that a stressful environment would cause changes in the chromosomes. 00:11:53.000 --> 00:12:05.000 Barbara McClintock referred to jumping genes, but these things were actual movement of DNA elicited by stress in the environment. 00:12:05.000 --> 00:12:19.000 And all of these people for almost 200 years were excluded from science by a very dogmatic view of genetics. 00:12:19.000 --> 00:12:27.000 All of the dogmatic view of the geneticists of the 20th century are now defunct completely, 00:12:27.000 --> 00:12:32.000 but they live on in practice and medicine. 00:12:32.000 --> 00:12:44.000 In the last year, several dozen people have asked me what to do because they've discovered that they're a mutant by having a DNA test. 00:12:44.000 --> 00:12:51.000 There are a couple of popular genes that almost everyone has a mutated form of, 00:12:51.000 --> 00:13:05.000 but actually these make almost no difference in health or function, a very slight nutritional requirement difference. 00:13:05.000 --> 00:13:14.000 And if you look at identical twins, despite the fact that all of their DNA is identical 00:13:14.000 --> 00:13:27.000 and they experience the same environment in the uterus and most of them experience a very similar environment because of their social economic level, 00:13:27.000 --> 00:13:38.000 despite all of those genetic and environmental overlaps, when you look at a serious disease, there's very little overlap. 00:13:38.000 --> 00:13:48.000 For example, if one twin has rheumatoid arthritis, there's only a 12% incidence of it in the other twin. 00:13:48.000 --> 00:14:02.000 And that's now well recognized, but still the gene testing industry is trying to sell the idea that you get sick if you have certain mutated genes. 00:14:02.000 --> 00:14:09.000 So you're saying it's more a product of the environment, perhaps in that arthritic type situation, perhaps? 00:14:09.000 --> 00:14:17.000 Yeah, and constantly, like they put 40 mice, I think it was, in a stimulating environment 00:14:17.000 --> 00:14:27.000 and found that just by the choices they made in their daily life, they became very different in personality and behavior. 00:14:27.000 --> 00:14:35.000 Just by where they happen to go in the environment, influencing what they learned, 00:14:35.000 --> 00:14:42.000 and over their lifetime, they became very recognizable individuals. 00:14:42.000 --> 00:14:54.000 And that would really upset medicine if they had to consider everyone as a unique individual all the way down to the way their genes work. 00:14:54.000 --> 00:15:05.000 Because there would be no exact definition of a disease, it would be your disease this month. 00:15:05.000 --> 00:15:11.000 Yeah, yeah. Interesting. I wonder what it is in the animals, in that mice study, perhaps, 00:15:11.000 --> 00:15:16.000 that made the individual mice do things differently that gave them a better outcome. 00:15:16.000 --> 00:15:25.000 Possibly just which one was the first one to be weaned and wander off and have an experience. 00:15:25.000 --> 00:15:30.000 And that stimulated them in a way that the others didn't experience. 00:15:30.000 --> 00:15:32.000 Thank you. Go on. 00:15:32.000 --> 00:15:35.000 The genes are being used constantly. 00:15:35.000 --> 00:15:49.000 Everything you do is using your genes in a certain way that varies according to whether you're awake or asleep, for example. 00:15:49.000 --> 00:15:58.000 But if you're starving day after day, this is going to pull up an accumulation of changes, 00:15:58.000 --> 00:16:07.000 not just a quick on and off effect of day and night or incidental experiences, 00:16:07.000 --> 00:16:18.000 but it will accumulate sort of an inertia and layer after layer will be laid down in the stuff around your genes, 00:16:18.000 --> 00:16:31.000 attaching carbon atoms to the DNA itself and attaching a great variety of molecules to the proteins that handle the genes, 00:16:31.000 --> 00:16:42.000 the histones that surround the chromosomes and move the genes to make them accessible for copying and functioning. 00:16:42.000 --> 00:16:50.000 These are relatively easy to change. The methylation is a little more sluggish. 00:16:50.000 --> 00:17:01.000 And when you're in an extremely stressful situation, a lot of your genes get turned off, methylated especially. 00:17:01.000 --> 00:17:08.000 And those can be identified in the chromosomes that you inherit from your father or mother specifically. 00:17:08.000 --> 00:17:20.000 So if your father had a very hard life, you can identify the highly methylated genes in your chromosomes that came from that hard life. 00:17:20.000 --> 00:17:22.000 So that's inheritable then? 00:17:22.000 --> 00:17:34.000 Yeah. And in animal experiments, it takes several generations for a very bad generation's experience to be removed 00:17:34.000 --> 00:17:40.000 when they're put into a normal environment. But if you put them into a super environment like the... 00:17:40.000 --> 00:17:42.000 Enriched environment. 00:17:42.000 --> 00:17:50.000 Enriched, yeah. It's very stimulating. You can repair the previous generation's damage very quickly. 00:17:50.000 --> 00:17:58.000 And some nutrients and drugs can do that, remove methyl groups from the DNA 00:17:58.000 --> 00:18:04.000 and attach more of the opening groups to the histones. 00:18:04.000 --> 00:18:07.000 Okay. Let's just let people know here. 00:18:07.000 --> 00:18:11.000 You're listening to Ask Your Herb Doctor on KMED Gallup 91.1 FM. 00:18:11.000 --> 00:18:17.000 And from now until the end of the show at 8 o'clock, you're invited to call in with any questions either related or unrelated, 00:18:17.000 --> 00:18:22.000 perhaps to this month's subject of aging and energy reversal. 00:18:22.000 --> 00:18:28.000 Dr. Raymond Peat is a specialist in hormone physiology and the aging process. 00:18:28.000 --> 00:18:31.000 He's having studied it for the last 35 years or so. 00:18:31.000 --> 00:18:37.000 So, yeah, let's just tell people the number again. I guess it's 923-3911. 00:18:37.000 --> 00:18:42.000 If you live outside the area, then 800 numbers, 1-800-KMUD-RAD. 00:18:42.000 --> 00:18:45.000 That's 1-800-568-3723. 00:18:45.000 --> 00:18:48.000 Okay. So let's perhaps go on then to the... 00:18:48.000 --> 00:18:53.000 what you've mentioned about methylation and demethylation and how that occurs, 00:18:53.000 --> 00:18:59.000 how that affects the gene, how it silences it, how it allows tumors to grow 00:18:59.000 --> 00:19:05.000 and how they have just found now in this piece of research that the very presence of this 00:19:05.000 --> 00:19:09.000 is a very diagnostic indicator for how well the tumor will continue to grow 00:19:09.000 --> 00:19:15.000 and how switching this off is actually a fairly new approach to cancer therapy. 00:19:15.000 --> 00:19:21.000 So, in terms of the process of methylation and how this happens 00:19:21.000 --> 00:19:27.000 and how this is also related to that train of thought, a fairly aberrant train of thought perhaps, 00:19:27.000 --> 00:19:34.000 but that fasting is good for you and going without is actually fairly healthful 00:19:34.000 --> 00:19:40.000 and if you starve yourself fairly regularly and live on a very meager caloric intake, 00:19:40.000 --> 00:19:45.000 you'll actually have a greater chance of longevity and it's not actually true, is it? 00:19:45.000 --> 00:19:56.000 No, it was definite about 70 years ago, a researcher named Clive McKay, I think it was, 00:19:56.000 --> 00:20:03.000 showed that restricting the food supply made animals live longer, 00:20:03.000 --> 00:20:11.000 but later people restricted the type of food, kept down the heavy metals in their diet alone 00:20:11.000 --> 00:20:16.000 and let them eat all the fat, protein and carbohydrate they wanted and they lived longer. 00:20:16.000 --> 00:20:19.000 Actually, Dr. Peat, would you hold it there a minute for us if you could? 00:20:19.000 --> 00:20:23.000 We've actually got a couple of callers on the air, so let's get these couple of callers in. 00:20:23.000 --> 00:20:27.000 First caller, you're on the air and where are you from, caller? 00:20:27.000 --> 00:20:30.000 Hi, this is Gina from Kansas. 00:20:30.000 --> 00:20:31.000 Canada. 00:20:31.000 --> 00:20:33.000 Kansas. 00:20:33.000 --> 00:20:34.000 Kansas? 00:20:34.000 --> 00:20:35.000 Kansas City. 00:20:35.000 --> 00:20:37.000 Okay, I'm sorry. 00:20:37.000 --> 00:20:39.000 Sorry, it's my accent, I'm foreign as well. 00:20:39.000 --> 00:20:42.000 Oh, no problem, we're all foreign. 00:20:42.000 --> 00:20:44.000 Go ahead, what's your question? 00:20:44.000 --> 00:20:52.000 My question is not about tonight's subject, but it's about estrogen and the reduction of estrogen 00:20:52.000 --> 00:20:59.000 or if there are any herbs that can function as an aromative inhibitor. 00:20:59.000 --> 00:21:05.000 My situation is that I'm in a high estrogen state. 00:21:05.000 --> 00:21:09.000 I'm in my 40s, but I am already post-menopausal. 00:21:09.000 --> 00:21:16.000 I enter menopause very early at about the age of 40. 00:21:16.000 --> 00:21:22.000 I also have or I have been diagnosed this year with Hashimoto 00:21:22.000 --> 00:21:30.000 and I have gained a lot of weight, like 40 pounds in just three years. 00:21:30.000 --> 00:21:37.000 Since the menopause, I was told that I probably also had Hashimoto for three years or so. 00:21:37.000 --> 00:21:44.000 But I have gone from 99 pounds to 139 in just three years. 00:21:44.000 --> 00:21:51.000 My progesterone is very low, even though I am supplementing with Progest-E. 00:21:51.000 --> 00:21:52.000 Okay. 00:21:52.000 --> 00:21:58.000 And very high FSH and LH. 00:21:58.000 --> 00:21:59.000 Right. 00:21:59.000 --> 00:22:08.000 I'm under a lot of stress, so even though the blood test shows the estrogen is low as well, 00:22:08.000 --> 00:22:13.000 I believe it's only because it's trapped in the cells. 00:22:13.000 --> 00:22:21.000 I don't believe I have high estrogen. I don't see how I could, considering I'm fat, I'm under stress, 00:22:21.000 --> 00:22:27.000 I have digestive problems and a lot of other issues. 00:22:27.000 --> 00:22:36.000 So since I can't raise the progesterone, even with supplementation and diet, 00:22:36.000 --> 00:22:42.000 such as raw carrots, low fiber, I still cannot pull it up. 00:22:42.000 --> 00:22:49.000 Would you suggest perhaps that I should take something as an aromatase inhibitor? 00:22:49.000 --> 00:22:56.000 Well, the main aromatase inhibitor that I'm familiar with is from nettle root, 00:22:56.000 --> 00:23:04.000 and that's really used as a kind of prostatic agent in men to treat benign prostatic hypertrophy 00:23:04.000 --> 00:23:06.000 by blocking that enzyme. 00:23:06.000 --> 00:23:15.000 In terms of your condition and what you said about the weight gain and your age, 00:23:15.000 --> 00:23:20.000 it's not uncommon at all for what you're saying to occur. 00:23:20.000 --> 00:23:24.000 I think it happens fairly commonly. 00:23:24.000 --> 00:23:30.000 Dr. Peat, in terms of this lady's supposed low progesterone levels 00:23:30.000 --> 00:23:37.000 and the estrogen that she's been exposed to having gone into early menopause at 40, 00:23:37.000 --> 00:23:45.000 I know that you'd probably be looking at her thyroid function as a main route 00:23:45.000 --> 00:23:54.000 with which to treat her situation in terms of her possible now Hashimoto's diagnosis. 00:23:54.000 --> 00:24:04.000 Yeah, almost everyone around the age of 40, that's when the highest ratio of estrogen to progesterone exists, 00:24:04.000 --> 00:24:10.000 but the trouble is the estrogen seems to drop when you measure it in the serum, 00:24:10.000 --> 00:24:16.000 even though it was at its very highest lifetime level around the age of 40. 00:24:16.000 --> 00:24:23.000 When progesterone falls, the estrogen can't be released from the cell, 00:24:23.000 --> 00:24:33.000 and so it doesn't appear in the serum until progesterone affects the cells to release it 00:24:33.000 --> 00:24:35.000 so that it can be measured. 00:24:35.000 --> 00:24:43.000 But that means that even without taking something to increase your progesterone, 00:24:43.000 --> 00:24:49.000 the aromatase inhibitors are very practical and logical. 00:24:49.000 --> 00:24:58.000 Two fruits that contain effective aromatase inhibitors are oranges and guavas, 00:24:58.000 --> 00:25:00.000 apigenin. 00:25:00.000 --> 00:25:02.000 So this is naringenin? 00:25:02.000 --> 00:25:07.000 Yeah, in oranges and then in guavas, I think there's one called apigenin. 00:25:07.000 --> 00:25:08.000 Apigenin, okay. 00:25:08.000 --> 00:25:09.000 Apigenin. 00:25:09.000 --> 00:25:10.000 Okay. 00:25:10.000 --> 00:25:21.000 And aspirin, by blocking the production of inflammatory prostaglandins, aspirin helps. 00:25:21.000 --> 00:25:30.000 And the supplement pregnenolone is indirectly able to increase your progesterone 00:25:30.000 --> 00:25:34.000 and lower the estrogen production. 00:25:34.000 --> 00:25:40.000 The pregnenolone is a precursor to the DHEA, correct? 00:25:40.000 --> 00:25:42.000 It's a what? 00:25:42.000 --> 00:25:43.000 Precursor, yeah. 00:25:43.000 --> 00:25:44.000 Oh, precursor. 00:25:44.000 --> 00:25:45.000 Yeah. 00:25:45.000 --> 00:25:46.000 Right. 00:25:46.000 --> 00:25:48.000 My DHEA levels are quite high. 00:25:48.000 --> 00:25:55.000 So would taking pregnenolone make it even higher? 00:25:55.000 --> 00:25:57.000 No. 00:25:57.000 --> 00:26:05.000 When your estrogen is not being controlled, it likely over-activates your adrenals. 00:26:05.000 --> 00:26:14.000 DHEA tends to go up with cortisol, and cortisol is a major activator of aromatase. 00:26:14.000 --> 00:26:22.000 And the function of pregnenolone is to lower the excess cortisol 00:26:22.000 --> 00:26:27.000 and prevent the overstimulation of aromatase. 00:26:27.000 --> 00:26:31.000 Okay. 00:26:31.000 --> 00:26:40.000 So if the pregnenolone being a precursor to DHEA, you explained how that works, 00:26:40.000 --> 00:26:43.000 but the DHEA is also a precursor to estrogen. 00:26:43.000 --> 00:26:49.000 So how would I keep it from producing even more estrogen? 00:26:49.000 --> 00:26:57.000 Sometimes the pregnenolone in itself can do that by lowering the stress hormones, 00:26:57.000 --> 00:27:01.000 which drive the adrenal glands too hard. 00:27:01.000 --> 00:27:10.000 And the diet to correct your low thyroid function is probably the basic thing. 00:27:10.000 --> 00:27:17.000 Estrogen causes basically inflammation of the thyroid gland. 00:27:17.000 --> 00:27:27.000 It inhibits the ability to secrete thyroid hormone while allowing it to synthesize it 00:27:27.000 --> 00:27:31.000 and respond to thyroid-stimulating hormone. 00:27:31.000 --> 00:27:36.000 And progesterone is needed for the gland to secrete. 00:27:36.000 --> 00:27:43.000 So you want to do things that lower the stress on your thyroid. 00:27:43.000 --> 00:27:50.000 And polyunsaturated fats are probably the most important factor in blocking the thyroid 00:27:50.000 --> 00:27:53.000 other than estrogen. 00:27:53.000 --> 00:27:54.000 Right. 00:27:54.000 --> 00:27:59.000 I have eliminated those now. 00:27:59.000 --> 00:28:00.000 Okay. 00:28:00.000 --> 00:28:01.000 Well, thank you very much. 00:28:01.000 --> 00:28:02.000 I appreciate your help. 00:28:02.000 --> 00:28:08.000 Calcium in the diet is a very important thing for keeping your metabolic rate up 00:28:08.000 --> 00:28:11.000 and helping to lose weight. 00:28:11.000 --> 00:28:16.000 How much calcium should I have a day? 00:28:16.000 --> 00:28:24.000 Two quarts of low-fat milk will provide a pretty ideal amount of calcium. 00:28:24.000 --> 00:28:25.000 Okay. 00:28:25.000 --> 00:28:26.000 Low-fat milk. 00:28:26.000 --> 00:28:28.000 Okay. 00:28:28.000 --> 00:28:35.000 Would that amount to be influenced by the fact that I have low stomach acid 00:28:35.000 --> 00:28:43.000 and I don't have a gallbladder so I don't absorb nutrients as well? 00:28:43.000 --> 00:28:54.000 Yeah, with one percent milk, there's enough to slow the absorption of the sugar and protein slightly 00:28:54.000 --> 00:28:59.000 but not enough fat to upset your gallbladder. 00:28:59.000 --> 00:29:01.000 Okay. 00:29:01.000 --> 00:29:02.000 Okay, thank you very much. 00:29:02.000 --> 00:29:03.000 I appreciate that. 00:29:03.000 --> 00:29:04.000 You're very welcome. 00:29:04.000 --> 00:29:05.000 Bye-bye. 00:29:05.000 --> 00:29:06.000 Bye-bye. 00:29:06.000 --> 00:29:10.000 Okay, there is another caller on the air so let's take this next caller before we carry on. 00:29:10.000 --> 00:29:11.000 Hi, caller. 00:29:11.000 --> 00:29:12.000 You're on the air and where are you from? 00:29:12.000 --> 00:29:14.000 Yes, this is David from Missouri. 00:29:14.000 --> 00:29:15.000 Oh, hi, David. 00:29:15.000 --> 00:29:16.000 Hello. 00:29:16.000 --> 00:29:23.000 So, you know, I just thought of something that might be helpful to all of us 00:29:23.000 --> 00:29:27.000 and Dr. Peat has really helped me a lot on this and he's discussed this quite a bit 00:29:27.000 --> 00:29:32.000 but, you know, we're at the lowest point in getting sunlight. 00:29:32.000 --> 00:29:35.000 We're getting close to the winter equinox 00:29:35.000 --> 00:29:41.000 and I've really been experimenting a lot with the red light, you know, using the heat lamps 00:29:41.000 --> 00:29:45.000 that is basically like a chicken light that you would go buy at a hardware store 00:29:45.000 --> 00:29:49.000 and having a reflector on it and really trying to get more of that light each day. 00:29:49.000 --> 00:29:52.000 So anybody that's having any kind of problems, 00:29:52.000 --> 00:29:57.000 a lot of the problems could be coming from the low light situation 00:29:57.000 --> 00:29:58.000 so that might be a good place to start. 00:29:58.000 --> 00:30:01.000 So anyway, I just wanted to start with that. 00:30:01.000 --> 00:30:05.000 The other thing, I just have a few questions about food in general 00:30:05.000 --> 00:30:09.000 and also about aspirin since you brought up aspirin. 00:30:09.000 --> 00:30:13.000 One of the problems with buying, like, you know, different brands like Bear and different things, 00:30:13.000 --> 00:30:16.000 it seems like they have a lot of additives in them 00:30:16.000 --> 00:30:21.000 and so I've explored different ways of getting aspirin that is pure aspirin. 00:30:21.000 --> 00:30:26.000 The only place you can actually buy that is through pet supply places 00:30:26.000 --> 00:30:29.000 which always feels a little weird, you know, buying it that way. 00:30:29.000 --> 00:30:33.000 But then the other thing, and Andrew, you probably know quite a bit about this as well, 00:30:33.000 --> 00:30:42.000 willow bark, which I guess is really the source of where Bear Aspirin originally got their, 00:30:42.000 --> 00:30:48.000 you know, their molecule structure to create the phyllic acid. 00:30:48.000 --> 00:30:52.000 I think it was also another very good rich source of acetylsalicylic acid, 00:30:52.000 --> 00:30:56.000 but I think it was probably the willow bark where it was first synthesized. 00:30:56.000 --> 00:31:01.000 Yeah, so I'm just curious, Dr. Peat, what do you think about using the willow bark 00:31:01.000 --> 00:31:04.000 rather than trying to use some of these aspirin that have all the fillers 00:31:04.000 --> 00:31:09.000 and different phyllic materials in them? 00:31:09.000 --> 00:31:11.000 The fillers definitely aren't good. 00:31:11.000 --> 00:31:19.000 I mean, if you have access to nothing but the pills, I think you should dissolve them in hot water 00:31:19.000 --> 00:31:25.000 to let the junk settle out and then just drink the sour water. 00:31:25.000 --> 00:31:27.000 Okay, I never thought of that. 00:31:27.000 --> 00:31:28.000 Okay. 00:31:28.000 --> 00:31:33.000 There is quite a few chemical supply companies actually that will sell it. 00:31:33.000 --> 00:31:36.000 I don't think it's a controlled substance. 00:31:36.000 --> 00:31:40.000 Dr. Peat, aspirin is not a controlled substance at this point in time, is it? 00:31:40.000 --> 00:31:41.000 No. 00:31:41.000 --> 00:31:42.000 Okay, yeah. 00:31:42.000 --> 00:31:43.000 Okay, well, that's good. 00:31:43.000 --> 00:31:47.000 It seems like the only-- I've done a lot of different searches and called a lot of places, 00:31:47.000 --> 00:31:50.000 and it seems like the only place you can find it is like Pet Supply, 00:31:50.000 --> 00:31:55.000 which it seems like in America sometimes they treat pets better than they do people. 00:31:55.000 --> 00:31:58.000 They don't give them as many additives, that's for sure, probably. 00:31:58.000 --> 00:32:00.000 No, you definitely can get too much of that. 00:32:00.000 --> 00:32:08.000 The other thing I wanted to ask about was on pressure cooking and canning. 00:32:08.000 --> 00:32:12.000 And the reason I'm thinking along those lines is, you know, we just kind of live in crazy times, 00:32:12.000 --> 00:32:16.000 so I've been thinking about, you know, trying to come up with some foods that could be canned, 00:32:16.000 --> 00:32:21.000 like in Mason jars, and I bought a pressure cooker. 00:32:21.000 --> 00:32:25.000 And so I just want to throw this one recipe that I'm thinking about doing out, 00:32:25.000 --> 00:32:31.000 and it would be potatoes and kale, garlic, onion, 00:32:31.000 --> 00:32:35.000 and I'm thinking also about using like ground lamb. 00:32:35.000 --> 00:32:40.000 Either cooking that in the pressure cooker in the jar or cooking it before, 00:32:40.000 --> 00:32:43.000 and I'm just curious if you have any thoughts about that. 00:32:43.000 --> 00:32:49.000 I would think the main thoughts Dr. Peat would have about that is the onion and garlic side of it. 00:32:49.000 --> 00:32:52.000 Oh, okay, so we would rather not put the onion and garlic in there? 00:32:52.000 --> 00:32:55.000 Well, I think that's because some people are fairly sensitive to it, 00:32:55.000 --> 00:32:58.000 and they may not even notice the onions and the garlic that are doing it. 00:32:58.000 --> 00:33:02.000 It's like people eating a lot of vegetables and then having a lot of flatulence 00:33:02.000 --> 00:33:05.000 and it's quite normal. It's actually not good for you, 00:33:05.000 --> 00:33:10.000 so you're probably better off without it. I think that's the logic. 00:33:10.000 --> 00:33:17.000 Do you think, Dr. Peat, that the nutrition aspects of the canning would harm the foods? 00:33:17.000 --> 00:33:26.000 Oh, no. There were experiments in the 1940s in which rats were fed stuff out of cans, 00:33:26.000 --> 00:33:33.000 the usual vegetables, beans, corn, all the standard vegetables, 00:33:33.000 --> 00:33:38.000 and others were fed the same vegetables, fresh and raw. 00:33:38.000 --> 00:33:44.000 The animals eating canned vegetables thrived. The others didn't. 00:33:44.000 --> 00:33:45.000 Interesting. 00:33:45.000 --> 00:33:51.000 So I'm thinking that the potatoes, because you've talked about potatoes actually being a fairly decent protein, 00:33:51.000 --> 00:33:55.000 even though I know the starch is a little bit of a problem, but if it's cooked really well, 00:33:55.000 --> 00:34:01.000 and I'm thinking the kale is a really good source of minerals and vitamin K, 00:34:01.000 --> 00:34:06.000 and then the lamb fat and the protein in the lamb I would think would all be really good. 00:34:06.000 --> 00:34:15.000 Yeah, the well-cooked green leaves are extremely good nutritionally, 00:34:15.000 --> 00:34:21.000 especially to balance meat because the greens contain very little phosphate 00:34:21.000 --> 00:34:26.000 and the meat contains too much phosphate and too little calcium, 00:34:26.000 --> 00:34:30.000 so you've got to balance when you have greens with meat. 00:34:30.000 --> 00:34:32.000 Okay, well, good. 00:34:32.000 --> 00:34:35.000 Well, I'll do some experiments on that and let everybody know how that turned out, 00:34:35.000 --> 00:34:42.000 but it seems like a fairly nutritious product to can, so. 00:34:42.000 --> 00:34:47.000 And then just one other thing, I was curious about calcium chloride, 00:34:47.000 --> 00:34:51.000 and I don't buy very many foods that have additives in them, 00:34:51.000 --> 00:34:58.000 but there's one thing that I do buy, and it's actually a really good brand of pickles. 00:34:58.000 --> 00:35:03.000 There's very little ingredients in them that I could see any problem with other than calcium chloride. 00:35:03.000 --> 00:35:06.000 I'm just curious, what do you think of calcium chloride? 00:35:06.000 --> 00:35:13.000 It's been used for making pickles and such, and it has a nice taste when it's added to food, 00:35:13.000 --> 00:35:20.000 but a lot of people are sensitive either to magnesium chloride or calcium chloride, 00:35:20.000 --> 00:35:23.000 and so it's good to be cautious with it. 00:35:23.000 --> 00:35:30.000 It can cause headaches and bowel symptoms of various types. 00:35:30.000 --> 00:35:36.000 So if I'm not having any problems that I can sense, then I guess it's probably fine. 00:35:36.000 --> 00:35:43.000 Yeah, if it's chemically pure, it's good as a food additive. 00:35:43.000 --> 00:35:45.000 Okay. 00:35:45.000 --> 00:35:47.000 Okay, well, hey, thank you. 00:35:47.000 --> 00:35:49.000 Okay, thanks for your call. 00:35:49.000 --> 00:35:50.000 Okay. 00:35:50.000 --> 00:35:55.000 Okay, so the number here if you live in the area is 923-3911, 00:35:55.000 --> 00:36:02.000 or the 800 number is 1-800-568-3723 or 1-800-KMUD-RAD. 00:36:02.000 --> 00:36:05.000 Okay, so the lines will be open until 8 o'clock. 00:36:05.000 --> 00:36:12.000 Dr. Peat, you were starting to talk about the -- 00:36:12.000 --> 00:36:18.000 well, I think between methylation and the compounds that would be useful 00:36:18.000 --> 00:36:25.000 that were brought out in the article, I know they talked about things like curcumin from turmeric. 00:36:25.000 --> 00:36:30.000 They mentioned resveratrol, which I know that you've looked at in fairly good detail. 00:36:30.000 --> 00:36:38.000 You mentioned genistein and diazine, which are other compounds that were useful in switching off that methylation. 00:36:38.000 --> 00:36:43.000 Do you have any other -- yeah, any other thoughts on that? 00:36:43.000 --> 00:36:46.000 The caller mentioned the importance of light, 00:36:46.000 --> 00:36:55.000 and even light can help to reverse the toxic methylation that happens from stress. 00:36:55.000 --> 00:36:58.000 Okay, to switch off that excitotoxicity. 00:36:58.000 --> 00:36:59.000 Yes. 00:36:59.000 --> 00:37:04.000 Because I know we've talked about that in the past, haven't we, about neurons becoming too excited, 00:37:04.000 --> 00:37:07.000 and that's just as bad as being inactive. 00:37:07.000 --> 00:37:14.000 So in terms of methylation, then, it's a bad process that happens to the genes, 00:37:14.000 --> 00:37:22.000 and it can happen through various mechanisms, not least of which can be nutritional. 00:37:22.000 --> 00:37:24.000 But you've mentioned things like red light. 00:37:24.000 --> 00:37:29.000 I know we've talked in the past in great detail about thyroid hormone, 00:37:29.000 --> 00:37:39.000 but is there any other things that would be counterproductive that you could use to counter the methylation in the genetics? 00:37:39.000 --> 00:37:49.000 Some of the people who have been told that they have mutated genes are being told by their doctors 00:37:49.000 --> 00:37:58.000 that they need to eat lots of methyl groups, choline and methionine in particular, 00:37:58.000 --> 00:38:05.000 to make up for the weak gene enzyme. 00:38:05.000 --> 00:38:16.000 But the American Medical Genetics -- College of Medical Genetics recently said 00:38:16.000 --> 00:38:23.000 that mutation doesn't call for basically any treatment. 00:38:23.000 --> 00:38:27.000 It's not significant clinically. 00:38:27.000 --> 00:38:39.000 But they didn't mention that people with that so-called mutation have a lower incidence of cancer, 00:38:39.000 --> 00:38:48.000 and this probably relates to what we're talking about, the epigenetic methylation of the genes. 00:38:48.000 --> 00:38:57.000 The people who have a slightly weaker methylation system are better off for cancer risk. 00:38:57.000 --> 00:39:03.000 Okay, because I wanted to bring out two compounds that are actually anesthetics, 00:39:03.000 --> 00:39:11.000 lidocaine and procaine, kind of related to the cocaine-type structure. 00:39:11.000 --> 00:39:17.000 So both lidocaine and procaine have a demethylation activity. 00:39:17.000 --> 00:39:20.000 Is that right for the DNA? 00:39:20.000 --> 00:39:24.000 Yeah, these are being studied in several types of cancer. 00:39:24.000 --> 00:39:32.000 Prostate, breast, pancreas, lung, and melanoma are the ones I've seen, 00:39:32.000 --> 00:39:40.000 and its effects are just dramatic for reversing those changes that are characteristic of the cancer. 00:39:40.000 --> 00:39:47.000 So it's being considered as an important new approach to cancer treatment, 00:39:47.000 --> 00:39:55.000 but it's so cheap that no one is very enthusiastic about applying to the FDA. 00:39:55.000 --> 00:39:59.000 It definitely hasn't got a patent on it still, correct? 00:39:59.000 --> 00:40:05.000 No, and it costs maybe a quarter a day or something. 00:40:05.000 --> 00:40:07.000 Yeah, oh dear. 00:40:07.000 --> 00:40:15.000 Okay, well, the other thing, in that BBC article they mentioned NAD being the molecule that was responsible here, 00:40:15.000 --> 00:40:21.000 and if I'm right in thinking that this compound can be synthesized from tryptophan-- 00:40:21.000 --> 00:40:29.000 I don't want to get confused here now. Have I not heard you mention that excess tryptophan is not good for you? 00:40:29.000 --> 00:40:37.000 Yeah, women in particular are very susceptible to too much tryptophan. 00:40:37.000 --> 00:40:42.000 They used to be the victims of pellagra much more often than men. 00:40:42.000 --> 00:40:57.000 That's because estrogen redirects the metabolism of tryptophan into serotonin rather than niacin or niacinamide. 00:40:57.000 --> 00:41:13.000 And when corn is treated with alkali to make hominy or tortillas, the chemistry shifts it over in that pathway, 00:41:13.000 --> 00:41:21.000 makes niacin out of it, and doesn't let so much serotonin be formed. 00:41:21.000 --> 00:41:27.000 Okay, because there was another chemical, aspartic acid. 00:41:27.000 --> 00:41:38.000 I also saw that was a good source from which NAD can be synthesized, and that was from asparagus and asparagus juice in particular. 00:41:38.000 --> 00:41:49.000 Well, you don't want to take plain aspartic acid or even with minerals because it's an excitotoxin in itself. 00:41:49.000 --> 00:41:52.000 How about asparagus juice as a source of it? 00:41:52.000 --> 00:41:54.000 Oh, it's fine. 00:41:54.000 --> 00:42:10.000 And another amino acid that's being promoted a lot in the internet world is either arginine or citrulline to increase your nitric oxide. 00:42:10.000 --> 00:42:15.000 That's going exactly in the wrong direction genetically. 00:42:15.000 --> 00:42:29.000 And the vitamin B6 is needed to prevent tryptophan being turned into too much serotonin and to help turn it into niacinamide. 00:42:29.000 --> 00:42:42.000 And simply supplementing niacinamide is a very direct way to help reverse these epigenetic problems. 00:42:42.000 --> 00:42:54.000 Five years ago when the Harvard people were starting a drug company, I think it was called Certis, S-I-R-T-I-S, 00:42:54.000 --> 00:43:08.000 which was bought by a big drug company, Glaxo, and they dumped it this year and went on to something else. 00:43:08.000 --> 00:43:12.000 You said that some of the chemicals that were uncovered might be useful in the future. 00:43:12.000 --> 00:43:20.000 Yeah, at the time the people promoting resveratrol through that company as an anti-aging chemical 00:43:20.000 --> 00:43:29.000 were warning that niacinamide antagonized resveratrol and lowered the sirtuins. 00:43:29.000 --> 00:43:35.000 And therefore niacinamide would accelerate aging. 00:43:35.000 --> 00:43:38.000 But I think now they've changed their story. 00:43:38.000 --> 00:43:48.000 And the facts over even at that time, five years ago, it was very clear that niacinamide greatly extended cell life. 00:43:48.000 --> 00:43:57.000 Just a tremendous increase in human cell longevity in vitro. 00:43:57.000 --> 00:44:09.000 And it's very safe, so it can be used in all of these epigenetic problems, Parkinson's disease, Alzheimer's disease, 00:44:09.000 --> 00:44:12.000 various types of cancer and so on. 00:44:12.000 --> 00:44:21.000 And it's interesting that all of these substances that have been known, some of them for thousands of years, 00:44:21.000 --> 00:44:30.000 as anti-inflammatory drugs, they all turn out to work in the same direction, 00:44:30.000 --> 00:44:40.000 protecting us from over-methylation and over-removal of the acetyl groups from the histones. 00:44:40.000 --> 00:44:44.000 Okay, hold it there, Dr. Peat. We've got a couple more callers, so let's take the next caller. 00:44:44.000 --> 00:44:46.000 You're on the air, and where are you from? 00:44:46.000 --> 00:44:49.000 Actually, someone called in. Quick question. I'll ask for them. 00:44:49.000 --> 00:44:54.000 What is the use of lidocaine, and how is it administered, and what sort of doses are there? 00:44:54.000 --> 00:44:56.000 And then there is another caller. 00:44:56.000 --> 00:44:58.000 Right. Not sure about the dose. 00:44:58.000 --> 00:45:00.000 Lidocaine for cancer was the question. 00:45:00.000 --> 00:45:02.000 Okay. Dr. Peat. 00:45:02.000 --> 00:45:11.000 These studies have been done in many different ways, but I've had several sort of random experiences 00:45:11.000 --> 00:45:19.000 with both protein and lidocaine that were really just amazing to me. 00:45:19.000 --> 00:45:28.000 For example, a girl with lifetime terrible eczema, red and scaly all over, 00:45:28.000 --> 00:45:36.000 she put a handful of, I think it was rubbing alcohol mostly, with some novocaine in it, 00:45:36.000 --> 00:45:44.000 and she stroked it up her shin, and at the same speed that her hand moved up her shin, 00:45:44.000 --> 00:45:52.000 a wave of normal-looking skin appeared right behind it, and it stayed that way. 00:45:52.000 --> 00:45:56.000 I've seen people with terrible burns. 00:45:56.000 --> 00:46:05.000 If they could get it on in the first minute or so, the burn stopped and didn't develop. 00:46:05.000 --> 00:46:13.000 It has antihistamine, antiserotonin effects, stopping inflammation in the tracts, 00:46:13.000 --> 00:46:20.000 but what it's doing, all of these well-known anti-inflammatory things 00:46:20.000 --> 00:46:32.000 are also undoing the limiting and harmful genetic changes that are caused by injury. 00:46:32.000 --> 00:46:40.000 It's almost as if the perception of pain itself accelerates the damage and the inflammation 00:46:40.000 --> 00:46:45.000 from that which caused the pain and inflammation in the first place. 00:46:45.000 --> 00:46:51.000 The nerves increase the release of the inflammatory materials. 00:46:51.000 --> 00:46:56.000 If you can block the signaling of pain, you can greatly reduce the symptoms 00:46:56.000 --> 00:46:59.000 of whatever the insult was in the first place. 00:46:59.000 --> 00:47:03.000 Interesting. OK, we do have another caller on the air, so let's take this next caller. 00:47:03.000 --> 00:47:05.000 Where are you from? 00:47:05.000 --> 00:47:06.000 They hung up. 00:47:06.000 --> 00:47:07.000 Oh, they hung up. OK. 00:47:07.000 --> 00:47:12.000 All right, well, if people would like to call back, the number's 923 3911 00:47:12.000 --> 00:47:18.000 or the toll-free number's 1-800-KMUD-RAD, so the lines will be open until about 5 to 8 here. 00:47:18.000 --> 00:47:26.000 OK, well, going back then to, we mentioned the NAD can be synthesized from tryptophan. 00:47:26.000 --> 00:47:31.000 Too much tryptophan is not good, especially in women with estrogen-related problems. 00:47:31.000 --> 00:47:39.000 And then the other thing was the asparagus juice, which also could be a source of a synthesis from that into NAD. 00:47:39.000 --> 00:47:48.000 You also mentioned, I read a couple of articles about how aspirin enhances the deacetylation of the histones, 00:47:48.000 --> 00:47:55.000 and the histones were these coils within a chromosome that kind of bundled up the DNA. 00:47:55.000 --> 00:48:04.000 And then aspirin itself was shown to greatly potentiate the effect of the deacetylation. 00:48:04.000 --> 00:48:12.000 And I know you've mentioned, you talk about aspirin a lot as being a very useful, very good anti-inflammatory, 00:48:12.000 --> 00:48:20.000 very inexpensive, and not at all to be considered as a life-threatening drug that will thin your blood and cause hemorrhage. 00:48:20.000 --> 00:48:29.000 But what do you think about the co-administration of aspirin along with that deacetylase inhibitor? 00:48:29.000 --> 00:48:38.000 I think it works by itself or with any of the other protective inhibitors. 00:48:38.000 --> 00:48:49.000 Caffeine has some of the same effects, and aspirin and caffeine have been used together in a lot of products. 00:48:49.000 --> 00:48:58.000 So a combination, all of these seem to work synergistically rather than interfering with each other. 00:48:58.000 --> 00:49:06.000 Okay. And there was, I think if we want to move on to the anthraquinones as a pretty interesting group of chemicals, 00:49:06.000 --> 00:49:15.000 I know Pau de Arco is being one of these chemicals that has got a long history of anti-cancer use. 00:49:15.000 --> 00:49:20.000 But talk about imodine as a compound, this anthraquinone, the reddish, 00:49:20.000 --> 00:49:27.000 the chemical that gives the reddish color to those types of chemicals that have that laxative effect, 00:49:27.000 --> 00:49:33.000 so both cascara and imodine, and how they work. 00:49:33.000 --> 00:49:39.000 If you look at the molecule for Pau de Arco, is that the same as Lapatron? 00:49:39.000 --> 00:49:41.000 Yeah. 00:49:41.000 --> 00:49:55.000 If you put vitamin K and imodine and Lapatron in a row and tetracycline, the antibiotic, which is an anti-inflammatory, 00:49:55.000 --> 00:50:00.000 they're essentially the same structure with a different number of rings. 00:50:00.000 --> 00:50:04.000 But it's like each one is an analog of the other, 00:50:04.000 --> 00:50:13.000 and each one has properties overlapping with those of the other anti-inflammatory, anti-cancer, anti-stress. 00:50:13.000 --> 00:50:17.000 Can I hold you there? I think there's three callers on the line now. 00:50:17.000 --> 00:50:18.000 Okay. 00:50:18.000 --> 00:50:21.000 Let's take the first caller. You're on the air, and where are you from? 00:50:21.000 --> 00:50:23.000 Hello, I'm from Arcata. 00:50:23.000 --> 00:50:25.000 Okay, hi. What's your question? 00:50:25.000 --> 00:50:29.000 You know, I have a problem. 00:50:29.000 --> 00:50:37.000 A couple of years ago, I scalded myself on my abdomen while I was cooking chicken. 00:50:37.000 --> 00:50:38.000 Okay. 00:50:38.000 --> 00:50:47.000 And the oil from the pan got on my abdomen, and a blister formed. 00:50:47.000 --> 00:50:51.000 And this blister was bulbous, you know. 00:50:51.000 --> 00:51:03.000 And since that time, I've had intervals. I've had blisters form again and again in the same location. 00:51:03.000 --> 00:51:08.000 And they've even, you know, spread a little bit. 00:51:08.000 --> 00:51:19.000 But if I put--I also have the problem where if I put adhesive tape, like a band-aid, on my abdomen in that area, the skin comes off. 00:51:19.000 --> 00:51:24.000 Yeah, it's very loosely connected to the underlying membrane. 00:51:24.000 --> 00:51:30.000 Yes, and this has been, you know--the blisters aren't a great problem. 00:51:30.000 --> 00:51:41.000 It's the--quite frequently, having to go through the process of healing from an open wound afterwards. 00:51:41.000 --> 00:51:47.000 How long after the initial accident have you found these episodes again? 00:51:47.000 --> 00:51:53.000 Oh, this--it started occurring like four months afterwards. 00:51:53.000 --> 00:51:58.000 The blister, the actual blister, and that went away. 00:51:58.000 --> 00:52:06.000 And then one day, I noticed--I'd taken a shower, and, you know, I noticed there was a blister forming. 00:52:06.000 --> 00:52:13.000 And it got very bulbous, about the size of a silver dollar or bigger. 00:52:13.000 --> 00:52:14.000 Okay. 00:52:14.000 --> 00:52:23.000 And, I mean, just--you know, and now, it's happened so frequently that there is, like, scar tissue there. 00:52:23.000 --> 00:52:24.000 Yeah, yeah. 00:52:24.000 --> 00:52:25.000 But it's still blisters. 00:52:25.000 --> 00:52:30.000 Well, Dr. Peat, this sounds very much like a kind of genetic imprinting, a memory. 00:52:30.000 --> 00:52:38.000 Yeah, and I think the nervous system is probably involved in helping with the memory. 00:52:38.000 --> 00:52:39.000 And there is-- 00:52:39.000 --> 00:52:44.000 All the skin doctors can say is, "We can replace the skin there." 00:52:44.000 --> 00:52:45.000 Yeah. 00:52:45.000 --> 00:52:48.000 And I don't think that's inappropriate. 00:52:48.000 --> 00:52:59.000 There is a little-known branch of medicine, I think it was a German who originated--I think it was called neural therapy or something like that. 00:52:59.000 --> 00:53:11.000 But it involved finding key points and injecting procaine or other local anesthetic to change the nervous system. 00:53:11.000 --> 00:53:22.000 And I've seen a great variety of good results from applying any of the local anesthetics topically to-- 00:53:22.000 --> 00:53:38.000 It apparently helps to retrain the memory of the tissue so that it stops producing the recurrent problem, such as an ingrown toenail or recurring boils in a certain location. 00:53:38.000 --> 00:53:41.000 Yes. 00:53:41.000 --> 00:53:47.000 There are a lot of fairly strong local anesthetic ointments sold over the counter. 00:53:47.000 --> 00:53:48.000 Okay. 00:53:48.000 --> 00:53:59.000 And I think benzocaine in a small area is effective and safe, but you don't want to use a lot of benzocaine on a big area. 00:53:59.000 --> 00:54:03.000 Procaine and lidocaine are safer. 00:54:03.000 --> 00:54:04.000 There we go. 00:54:04.000 --> 00:54:11.000 You could definitely try that because it does sound like there's some kind of imprinted memory in what happened for that to come back. 00:54:11.000 --> 00:54:22.000 I tried to look it up and there were several things I found on the Internet, but none of them suggest any type of treatment. 00:54:22.000 --> 00:54:28.000 And the big thing is that I would have an open sore there until that healed. 00:54:28.000 --> 00:54:40.000 And it healed rather rapidly, except at times it would form a false crust, a false scab, which would come off. 00:54:40.000 --> 00:54:45.000 You could definitely try that anesthetic cream and try that as a next thing to do. 00:54:45.000 --> 00:54:46.000 Yeah. 00:54:46.000 --> 00:54:47.000 All right. 00:54:47.000 --> 00:54:48.000 Thank you very much. 00:54:48.000 --> 00:54:49.000 You're very welcome. 00:54:49.000 --> 00:54:50.000 Okay. 00:54:50.000 --> 00:54:52.000 I think we have two more callers, so let's get the next caller on the end. 00:54:52.000 --> 00:54:54.000 Where are you from? 00:54:54.000 --> 00:54:55.000 Is that me? 00:54:55.000 --> 00:54:56.000 Yes, you're on the air. 00:54:56.000 --> 00:54:57.000 Where are you from? 00:54:57.000 --> 00:54:59.000 I just have a really quick question. 00:54:59.000 --> 00:55:13.000 The doctor mentioned about the woman who was using alcohol and something else, a person, and the eczema just disappeared instantly. 00:55:13.000 --> 00:55:15.000 What was the other thing? 00:55:15.000 --> 00:55:17.000 Was it lidocaine, Dr. Peat, or was it -- 00:55:17.000 --> 00:55:21.000 No, that particular one was just Novocaine, Procaine. 00:55:21.000 --> 00:55:22.000 Okay. 00:55:22.000 --> 00:55:23.000 All right. 00:55:23.000 --> 00:55:24.000 Well, thank you. 00:55:24.000 --> 00:55:25.000 That's what I wanted to know. 00:55:25.000 --> 00:55:26.000 Okay. 00:55:26.000 --> 00:55:31.000 It will dissolve in water, but a little alcohol makes it dissolve faster. 00:55:31.000 --> 00:55:32.000 Okay. 00:55:32.000 --> 00:55:36.000 Well, there is another caller, so if we can get the next caller done in two minutes, that would be good. 00:55:36.000 --> 00:55:39.000 So where are you from, caller? 00:55:39.000 --> 00:55:43.000 Hello, you're on the air. 00:55:43.000 --> 00:55:44.000 Maybe not, huh? 00:55:44.000 --> 00:55:45.000 Okay. 00:55:45.000 --> 00:55:46.000 Well, let's just leave that. 00:55:46.000 --> 00:55:48.000 It's probably getting too late anyway. 00:55:48.000 --> 00:55:50.000 So, yeah, we were talking very briefly, then, Dr. Peat. 00:55:50.000 --> 00:55:52.000 We've got a couple of minutes before the end of the show. 00:55:52.000 --> 00:56:03.000 I know that Imodine and another laxative from Cascara were definitely used to suppress bladder cancer cell growth. 00:56:03.000 --> 00:56:05.000 I saw an article about that. 00:56:05.000 --> 00:56:08.000 Do you know much more about Imodine? 00:56:08.000 --> 00:56:25.000 It's about 10 or 15 years ago, the FDA was attacking the laxatives of that class, such as Aloe and Cascara, as potential causes of cancer. 00:56:25.000 --> 00:56:39.000 But as soon as they took it off the market, the cancer industry started getting interested in it, and it relieves or cures many kinds of cancer. 00:56:39.000 --> 00:56:47.000 And it turns out not to have any of the harmful effects that the FDA was claiming. 00:56:47.000 --> 00:57:06.000 Its mechanism seems to involve not only the usual anti-inflammatory things, but a real basic reprogramming, demethylation, and inhibiting the histone deacetylase enzymes. 00:57:06.000 --> 00:57:07.000 Okay, good. 00:57:07.000 --> 00:57:09.000 Well, Dr. Peat, I don't want to keep you going. 00:57:09.000 --> 00:57:11.000 Thanks so much for joining us. 00:57:11.000 --> 00:57:16.000 I just want people to find out a little bit more about you and how to get access to the articles that you've written. 00:57:16.000 --> 00:57:17.000 So thanks for joining us. 00:57:17.000 --> 00:57:18.000 Okay. 00:57:18.000 --> 00:57:19.000 Merry Christmas. 00:57:19.000 --> 00:57:21.000 Thanks so much for all your help during the year. 00:57:21.000 --> 00:57:22.000 Okay. 00:57:22.000 --> 00:57:32.000 Okay, so for those people that have listened to the show, Dr. Raymond Peat, his website can be found at www.raypeat.com. 00:57:32.000 --> 00:57:40.000 The website is full of articles that are fully referenced about a lot of interesting research that he has done himself, 00:57:40.000 --> 00:57:46.000 and research which he has collated from other independent researchers far and wide. 00:57:46.000 --> 00:57:51.000 So there's a lot of very interesting information that is very scientifically referenced and backed up. 00:57:51.000 --> 00:57:53.000 None of it is just hearsay. 00:57:53.000 --> 00:57:58.000 So for those people that have listened to the show, thanks so much for joining us. 00:57:58.000 --> 00:58:01.000 And for those people that called in, thanks for your calls. 00:58:01.000 --> 00:58:08.000 It's going to be the solstice tomorrow, the shortest day of the year, and days are gradually going to get longer. 00:58:08.000 --> 00:58:12.000 So right now is the time you need to be thinking about your low thyroid activity 00:58:12.000 --> 00:58:19.000 and what you can do to help your thyroid through this darkest time until the beginning of the light coming back again. 00:58:19.000 --> 00:58:23.000 And, yeah, for all those people that have listened, thanks so much for your input. 00:58:23.000 --> 00:58:35.000 And we can be reached toll-free after business hour, during business hour, sorry, for consultations or whatever else you'd like to contact me about. 00:58:35.000 --> 00:58:40.000 The number is 1-888-926-4372. 00:58:40.000 --> 00:58:44.000 And Merry Christmas to all of you and a Happy New Year. 00:58:45.000 --> 00:58:56.000 [Music] 00:58:56.000 --> 00:59:01.000 >> Came with thanks Jessica Baker of Jade Dragon Acupuncture for her support of Redwood Community Radio. 00:59:01.000 --> 00:59:08.000 Practicing traditional Chinese medicine, Jessica treats conditions ranging from psoriasis to post-traumatic stress. 00:59:08.000 --> 00:59:20.000 Located at 607 F Street, Arcata, Jade Dragon Acupuncture can be reached at 822-4300 or online at jadedragonacupuncture.com. 00:59:20.000 --> 00:59:34.000 This is Redwood Community Radio, KMUD, Garberville 91.1 FM, KMUE, Eureka 88.1 FM, KLAI 90.3 FM, and FM Translator K258BQ in Shelter Cove. 00:59:34.000 --> 00:59:41.000 At 99.5 we are also live and archived on the web at kmud.org. 00:59:41.000 --> 00:59:46.000 All of you out of the area Dr. Peat listeners, check out the archive. 00:59:46.000 --> 00:59:49.000 You will find incredible programming of all sorts. 00:59:49.000 --> 00:59:51.000 Thank you very much to Andrew. 00:59:51.000 --> 00:59:55.000 And get ready, because Cousin Mark is in the house. 00:59:55.000 --> 00:59:58.000 It's time to get funked up. 00:59:58.000 --> 01:00:11.000 [Music] 01:00:11.000 --> 01:00:16.000 Please remember that 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