WEBVTT 00:00:00.000 --> 00:00:05.080 specializing in healthy kitchenware and food preserving supplies like stainless steel dehydrators 00:00:05.080 --> 00:00:08.000 and old world pickling crocks. 00:00:08.000 --> 00:00:15.000 Organic Grace is on the main street in Garberville and is on the web at organicgrace.com. 00:00:15.000 --> 00:00:18.800 And as usual throughout the broadcast day, the views and opinions expressed on Redwood 00:00:18.800 --> 00:00:22.880 Community Radio are those of the speakers and not necessarily those of the listeners, 00:00:22.880 --> 00:00:27.080 sorry, certainly not necessarily those of the listeners, but not necessarily those of 00:00:27.080 --> 00:00:33.240 the station, the underwriters, or the board of directors. 00:00:33.240 --> 00:00:37.800 And it could easily be sarcasm, but of course sarcasm is totally easy to understand on the 00:00:37.800 --> 00:00:41.600 radio, so you would know it if it is. 00:00:41.600 --> 00:00:49.080 And without further ado, we'll get to our next talk show, which is Ask Your Herb Doctor. 00:00:49.080 --> 00:00:54.080 Oops. 00:00:55.080 --> 00:00:58.080 [Music] 00:00:58.080 --> 00:01:01.080 [Applause] 00:01:02.080 --> 00:01:05.080 [Music] 00:01:06.080 --> 00:01:09.080 [Applause] 00:01:09.080 --> 00:01:13.080 [Music] 00:01:13.080 --> 00:01:17.080 [Applause] 00:01:17.080 --> 00:01:21.080 [Music] 00:01:21.080 --> 00:01:25.080 [Applause] 00:01:25.080 --> 00:01:29.080 [Music] 00:01:29.080 --> 00:01:33.080 [Applause] 00:01:34.080 --> 00:01:37.080 [Music] 00:01:37.080 --> 00:01:41.080 [Applause] 00:01:41.080 --> 00:01:45.080 [Music] 00:01:45.080 --> 00:01:49.080 [Applause] 00:01:49.080 --> 00:01:53.080 [Music] 00:01:53.080 --> 00:01:57.080 [Applause] 00:01:57.080 --> 00:02:01.080 [Music] 00:02:02.080 --> 00:02:05.080 [Applause] 00:02:05.080 --> 00:02:09.080 [Music] 00:02:09.080 --> 00:02:13.080 [Applause] 00:02:13.080 --> 00:02:17.080 [Music] 00:02:17.080 --> 00:02:21.080 [Applause] 00:02:21.080 --> 00:02:25.080 [Music] 00:02:25.080 --> 00:02:29.080 [Applause] 00:02:30.080 --> 00:02:33.080 [Music] 00:02:33.080 --> 00:02:37.080 [Music] 00:02:37.080 --> 00:02:44.080 Well, thank you once again. This is Ask Your Herb Doctor, KMU DeGarboville, 91.1 FM. 00:02:44.080 --> 00:02:49.080 My name's Andrew Murray, and for those of you who perhaps have never listened to the 00:02:49.080 --> 00:02:54.080 show, which runs every third Friday of the month from 7 to 8pm, I'm a licensed medical 00:02:54.080 --> 00:02:59.080 herbalist who trained in England and graduated there with a degree in herbal medicine. 00:02:59.080 --> 00:03:03.080 My wife and I run a clinic in Garboville where we consult with clients about a wide range 00:03:03.080 --> 00:03:09.080 of conditions and recommend herbal medicines and dietary advice, and has become very consistent 00:03:09.080 --> 00:03:15.080 with the last couple of years. Dr. Peat is happily joining us on the show to share his 00:03:15.080 --> 00:03:21.080 latest discoveries in his research. So, you're listening to Ask Your Herb Doctor on KMU DeGarboville, 00:03:21.080 --> 00:03:26.080 91.1 FM, and from 7.30 until the end of the show at 8 o'clock, you're invited to call 00:03:26.080 --> 00:03:33.080 in with any questions either related or unrelated to this month's subject of nitric oxide. 00:03:33.080 --> 00:03:39.080 The number, if you live in the area, is 923 3911, or if you live outside the area, the 00:03:39.080 --> 00:03:47.080 toll-free number is 1800 KMUD RAD, and we can be reached toll-free on 1-888-WBM-HERB 00:03:47.080 --> 00:03:52.080 for consultations or further information Monday through Friday, 9 to 5. 00:03:52.080 --> 00:03:55.080 So, Dr. Peat, thanks so much for joining us again. 00:03:55.080 --> 00:04:02.080 For those, perhaps, people who have never heard you, would you give an outline of your 00:04:02.080 --> 00:04:06.080 academic and professional background so that people can understand the work that you've 00:04:06.080 --> 00:04:07.080 been doing? 00:04:07.080 --> 00:04:16.080 First, I studied for a master's degree at the University of Oregon in literature-related 00:04:16.080 --> 00:04:21.080 things, and then studied linguistics for a while. Finally, came back to study biology, 00:04:21.080 --> 00:04:34.080 1968 to '72, specializing in physiology of reproduction and aging, and especially the 00:04:34.080 --> 00:04:38.080 biochemical side of aging physiology. 00:04:38.080 --> 00:04:48.080 Okay. All right. So, I wanted to ask you some questions about your most recent newsletter, 00:04:48.080 --> 00:04:56.080 which was based on nitric oxide, and hopefully open it up for people to understand the context 00:04:56.080 --> 00:05:01.080 in which we're talking about as a product. I think the very first question that I wanted 00:05:01.080 --> 00:05:09.080 to pose, given that the compound manufactured by Pfizer will be well known to many, both 00:05:09.080 --> 00:05:19.080 in its generic form and in the off-counter or other brand label types of product, being 00:05:19.080 --> 00:05:27.080 Viagra, nitric oxide majorly has a vasodilatory effect, as I understand it. That's just one 00:05:27.080 --> 00:05:32.080 of them, though, I guess, that's mediated by Viagra. And that drug is approved, or has 00:05:32.080 --> 00:05:35.080 an FDA approval, for erectile dysfunction. 00:05:35.080 --> 00:05:40.080 What is it about nitric oxide that makes it so dangerous and responsible for things like 00:05:40.080 --> 00:05:47.080 cardiac arrest, stroke, arrhythmias, and also increased ocular pressure, which most people 00:05:47.080 --> 00:05:53.080 wouldn't even associate with Viagra, but I've had several people who have used it and have 00:05:53.080 --> 00:06:00.080 had heart attack and stroke. And that prompted me to even look at it as being something that 00:06:00.080 --> 00:06:05.080 should definitely be taken seriously. And I know also the kind of recreational drug 00:06:05.080 --> 00:06:13.080 users who use poppers, exactly the same compound, has some very damaging effects on the body. 00:06:13.080 --> 00:06:16.080 What's your take on nitric oxide? 00:06:16.080 --> 00:06:27.080 Speaking of poppers, several of the early theorists of AIDS were blaming it on whatever 00:06:27.080 --> 00:06:33.080 the chemical is. I guess it's nitric oxide that's produced from the poppers, some kind 00:06:33.080 --> 00:06:40.080 of nitric compound anyway. And they were arguing that that in itself was enough to account 00:06:40.080 --> 00:06:51.080 for the AIDS among the people who were using that as a pleasure drug. But in the 1980s, 00:06:51.080 --> 00:07:01.080 everyone knew nitric oxide primarily as a toxic component of smog. So when people started 00:07:01.080 --> 00:07:08.080 discovering that it was being produced in small amounts in the body, immediately they 00:07:08.080 --> 00:07:18.080 started looking for the parallels with smog poisoning, lung injury, circulatory disease, 00:07:18.080 --> 00:07:25.080 and so on. And one of the first things they found was that it kills the beta cells in 00:07:25.080 --> 00:07:33.080 the pancreas that produce insulin. So in the early 1940s, there was this flurry of papers 00:07:33.080 --> 00:07:44.080 demonstrating that our internal smog is just as toxic as Los Angeles smog. But then the 00:07:44.080 --> 00:07:54.080 Viagra patent and publicity came out in the later 1990s. And right then, suddenly the 00:07:54.080 --> 00:08:04.080 medical publications all found that it was a glorious, protective, natural, protecting 00:08:04.080 --> 00:08:11.080 just about every function you can think of, making you smarter, have more endurance, and 00:08:11.080 --> 00:08:20.080 all kinds of good things. But then after a few years, I guess the investment in publicity 00:08:20.080 --> 00:08:29.080 started wearing off and people started coming back to the diabetes producing effects and 00:08:29.080 --> 00:08:42.080 looking at what it's actually doing biochemically. The basic way it causes harm probably is that 00:08:42.080 --> 00:08:53.080 it is kind of parallel to the effects of carbon monoxide or cyanide in being a competitor 00:08:53.080 --> 00:09:03.080 for oxygen in the mitochondria, the enzymes that produce most of our energy. It in several 00:09:03.080 --> 00:09:13.080 ways knocks out not only the key final respiratory enzyme, cytochrome oxidase, but it poisons 00:09:13.080 --> 00:09:24.080 the previous electron transporting parts of the mitochondrion too. So simply turning off 00:09:24.080 --> 00:09:33.080 the energy supply can account for a lot of its problems. But it also, when you're stopping 00:09:33.080 --> 00:09:44.080 the oxidative run through the mitochondrion, the mitochondrion starts leaking, in effect, 00:09:44.080 --> 00:09:53.080 electrons that have no place to go. And the whole cell shifts over to a reduced chemical 00:09:53.080 --> 00:10:02.080 state. The electrons aren't being constantly drawn down. And so the balance, if you imagine 00:10:02.080 --> 00:10:10.080 a stream of electrons falling steadily towards oxygen, when you cut off that, they accumulate 00:10:10.080 --> 00:10:21.080 and float back. And literally the reducing environment shifts the whole balance of the 00:10:21.080 --> 00:10:29.080 self-reduced sulfur compounds and it's expressed all the way out to the surface. And the surface 00:10:29.080 --> 00:10:38.080 properties of the cell change. And there are some enzymes right across the surface so that 00:10:38.080 --> 00:10:48.080 this reducing energy from inside the cell is available to reduce oxygen outside the 00:10:48.080 --> 00:10:56.080 cells. And mitochondria aren't using it productively. In fact, this cloud of excess electrons flows 00:10:56.080 --> 00:11:07.080 through the enzyme called NADPH oxidase and directly reduces oxygen on the surface. And 00:11:07.080 --> 00:11:17.080 that produces superoxide, possibly toxic free radical, which then produces hydrogen peroxide. 00:11:17.080 --> 00:11:27.080 And in the immune cells that are under stress, that's considered productive because it helps 00:11:27.080 --> 00:11:40.080 to break down bacteria or whatever is exciting, disturbing the white blood cell. So this toxic 00:11:40.080 --> 00:11:53.080 oxidative burst has its useful aspects, but probably it's one of the better outcomes rather 00:11:53.080 --> 00:12:08.080 than just using the hydrogen peroxide directly or producing nitric oxide. This hydrogen peroxide 00:12:08.080 --> 00:12:18.080 can be used to oxidize chloride that is always present into hypochlorite, which becomes one 00:12:18.080 --> 00:12:28.080 of the very strong germ digesting chemicals that when a phagocyte has eaten something, 00:12:28.080 --> 00:12:35.080 then basically it's like Clorox. It helps break down the particle. 00:12:35.080 --> 00:12:43.080 Okay, so in general, the nitric oxide forms of a pretty energy wasteful mechanism and 00:12:43.080 --> 00:12:47.080 also damaging in its free radical producing effects. 00:12:47.080 --> 00:12:59.080 Yeah, this shift of the whole cell away from oxidation starts that whole process that people 00:12:59.080 --> 00:13:05.080 are still just starting to put together the whole picture of how it fits into physiology. 00:13:05.080 --> 00:13:13.080 But it has its effects on the nervous system that people are now seeing that Parkinson's 00:13:13.080 --> 00:13:25.080 disease, for example, has the signs that nitric oxide is one of the central damaging components 00:13:25.080 --> 00:13:29.080 of the dopamine system. 00:13:29.080 --> 00:13:36.080 Okay, you're listening to Ask Your Herb Doctor on KMED Galbraith 91.1 FM. From 7.30 to the 00:13:36.080 --> 00:13:41.080 end of the show at 8 o'clock, callers are invited to ask questions about this month's 00:13:41.080 --> 00:13:46.080 subject of nitric oxide and the ramifications thereof. It doesn't have to be specifically 00:13:46.080 --> 00:13:51.080 about this subject. I know people often call in about other subjects that Dr. Peat's well 00:13:51.080 --> 00:13:56.080 versed in, like thyroid, etc. But the number here in the area is 9233911, or if you're 00:13:56.080 --> 00:14:02.080 outside the area, there's a toll-free number, which is 1800 KMUD RAD. 00:14:02.080 --> 00:14:12.080 So, so far as the damaging effects of nitric oxide are concerned, I think there are three 00:14:12.080 --> 00:14:18.080 species of nitric oxide, and the one I think that's most commonly referenced in PubMed 00:14:18.080 --> 00:14:24.080 and other scientific literature for its effects, both negative and for the small beneficial 00:14:24.080 --> 00:14:33.080 effect of its burst, energy burst effect on bacteria, etc., is the inducible nitric oxide 00:14:33.080 --> 00:14:39.080 synthase. And that's been implicated in causing an increased severity of disease in quite 00:14:39.080 --> 00:14:45.080 a few different models, one of which was a herpes simplex model and kephalitis, which 00:14:45.080 --> 00:14:51.080 is a brain inflammation in mice. And then I saw other references as well to chronic 00:14:51.080 --> 00:14:56.080 viral hepatitis in man, is definitely being aggravated by nitric oxide, and potentially 00:14:56.080 --> 00:15:04.080 nitric oxide suppression might be a useful treatment for people suffering from chronic 00:15:04.080 --> 00:15:10.080 hepatitis. What are the most reasonable ways of blocking nitric oxide synthesis in the 00:15:10.080 --> 00:15:14.080 body, or at least managing its production and providing a buffer to it, so that you 00:15:14.080 --> 00:15:22.080 can maintain the little nitric oxide that is beneficial whilst keeping in check any 00:15:22.080 --> 00:15:31.080 excess? The body has its various natural ways of keeping it under control. For example, 00:15:31.080 --> 00:15:40.080 progesterone inhibits the enzyme that makes nitric oxide, while estrogen excites and activates 00:15:40.080 --> 00:15:50.080 that enzyme. And so when the cell is stabilized by a generous amount of progesterone and related 00:15:50.080 --> 00:16:00.080 neuro steroids, the stabilizing things, including pregnenolone, those hold down the production. 00:16:00.080 --> 00:16:09.080 Anything that irritates the cell and excites it, the endotoxin from the intestine is probably 00:16:09.080 --> 00:16:19.080 the biggest single constant promoter of the production of nitric oxide. And sometimes 00:16:19.080 --> 00:16:28.080 serotonin and histamine, which are produced in reaction to endotoxin and other irritating 00:16:28.080 --> 00:16:38.080 things, these can increase in various tissues. Serotonin and histamine can increase the formation 00:16:38.080 --> 00:16:53.080 of nitric oxide. In some situations, caffeine and similar drugs that are known to have a 00:16:53.080 --> 00:17:02.080 variety of protective antitoxic effects are acting by locally in a certain type of tissue, 00:17:02.080 --> 00:17:15.080 turning down the nitric oxide production. But in recent years, the old dye, it was used 00:17:15.080 --> 00:17:25.080 as a treatment for malaria 100 years ago, called methylene blue. It's a common lab chemical 00:17:25.080 --> 00:17:32.080 used for showing the presence of a reducing compound. For example, vitamin C turns it 00:17:32.080 --> 00:17:45.080 white. Lots of people use it to demonstrate chemistry in a visible form. It's being used 00:17:45.080 --> 00:17:56.080 for a tremendous variety of therapeutic purposes. And simply by turning down nitric oxide, which 00:17:56.080 --> 00:18:04.080 causes so many bad effects, methylene blue is having very positive effects in this great 00:18:04.080 --> 00:18:16.080 variety of things, including herpes and other viral, chronic viral diseases. 00:18:16.080 --> 00:18:26.080 The recent news about the Ebola virus, some people have noticed that one of the things, 00:18:26.080 --> 00:18:35.080 if the patient is going to die, their nitric oxide level in the blood is very high. And 00:18:35.080 --> 00:18:42.080 it's what is causing the blood vessels to leak and break down, causing blood to leak 00:18:42.080 --> 00:18:50.080 out every place that it shouldn't. But you see something similar in ordinary influenza 00:18:50.080 --> 00:18:59.080 and other viral infections. The blood vessels tend to become leaky and produce swelling 00:18:59.080 --> 00:19:07.080 and a lot of very common side effects that you see in diseases of all sorts. 00:19:07.080 --> 00:19:13.080 What would you think would be a good short-term approach to that, to block that? 00:19:13.080 --> 00:19:24.080 From what's available presently, niacinamide and progesterone are things that are commonly 00:19:24.080 --> 00:19:33.080 available. But methylene blue is probably, when it's available, it's probably a good 00:19:33.080 --> 00:19:43.080 emergency thing to turn off the massive amounts of overproduced nitric oxide. 00:19:43.080 --> 00:19:50.080 I did read an article, I think there were several references to methylene blue and its 00:19:50.080 --> 00:19:56.080 use either promoting or suppressing depending on a dose. And it seemed like very small amounts 00:19:56.080 --> 00:20:03.080 of methylene blue were having this favorable suppressive activity where larger amounts 00:20:03.080 --> 00:20:05.080 could actually cause... 00:20:05.080 --> 00:20:14.080 Yeah, some of the toxicity experiments have been kind of ridiculous in which they feed 00:20:14.080 --> 00:20:22.080 rats the equivalent, if for a person it would be an ounce or two of crystalline methylene 00:20:22.080 --> 00:20:34.080 blue, which it would just that amount of concentrated any chemical is going to be harmful. But it's 00:20:34.080 --> 00:20:46.080 been 25 years ago, someone did a very well-controlled study of severe depressed people. 15 milligrams 00:20:46.080 --> 00:20:59.080 per day was all it took to relieve severe depression. And the side effects of even many 00:20:59.080 --> 00:21:05.080 times higher doses than that are essentially zero. 00:21:05.080 --> 00:21:18.080 Two studies, one by the NIH six years ago and one more recent, gave graded doses up 00:21:18.080 --> 00:21:25.080 to what would be the equivalent of about four or five or six grams a day for a person of 00:21:25.080 --> 00:21:34.080 the crystalline material, many times higher than the curative antidepressive dose. And 00:21:34.080 --> 00:21:43.080 they did it for the whole lifespan of rats and mice and saw no life-shortening effects 00:21:43.080 --> 00:21:51.080 in either rats or mice. But in female mice, in both studies, they saw an extension of 00:21:51.080 --> 00:21:55.080 the maximum lifespan with the highest dose. 00:21:55.080 --> 00:22:06.080 So in these ridiculously high doses, many times, I guess about five to 10 times higher 00:22:06.080 --> 00:22:14.080 than the dose Paul Ehrlich used more than a hundred years ago to treat malaria. And 00:22:14.080 --> 00:22:22.080 he cured two cases of malaria in a period of just a couple of weeks, giving five doses 00:22:22.080 --> 00:22:33.080 a day of 100 milligrams each time orally. But with very much smaller doses, you see 00:22:33.080 --> 00:22:41.080 changes in the brain and reduced stress and curing depression and so on. 00:22:41.080 --> 00:22:49.080 But with several times higher doses than he used to cure malaria, you still don't see 00:22:49.080 --> 00:22:59.080 any harmful effects. And in animal experiments, it took one of the gigantic doses equivalent 00:22:59.080 --> 00:23:06.080 to, I think it was about eight grams a day for a person before it stopped showing the 00:23:06.080 --> 00:23:09.080 simple antidepressive actions. 00:23:09.080 --> 00:23:15.080 Now, do you think the effects of methylene blue are, there's probably multiple effects, 00:23:15.080 --> 00:23:24.080 but I wonder if any of the electron quenching or electrical stabilizing activity of methylene 00:23:24.080 --> 00:23:32.080 blue might be responsible for interacting with different proteins and that kind of... 00:23:32.080 --> 00:23:42.080 Yeah, one of the known mechanisms is that it can receive electrons from the mediator 00:23:42.080 --> 00:23:51.080 that receives them from glucose. And NADH, for example, can be oxidized and then the 00:23:51.080 --> 00:23:59.080 methylene blue can pass those electrons onto the part of the mitochondrion that is still 00:23:59.080 --> 00:24:09.080 working, bypassing damaged parts of the mitochondrion. So it can act like the missing enzyme, simply 00:24:09.080 --> 00:24:22.080 restoring mitochondrial function. But in subtler ways, for example, the receptor that causes 00:24:22.080 --> 00:24:31.080 excitotoxic damage from overdoses of glutamic acid, for example, anything that is depleting 00:24:31.080 --> 00:24:42.080 the brain of energy while stimulating it activates these glutamate receptors. And there are two 00:24:42.080 --> 00:24:52.080 sulfur groups in those proteins that respond to excitotoxins that methylene blue oxidizes 00:24:52.080 --> 00:24:59.080 those and turns off the receptor and stops the excitotoxic process. And that's one of 00:24:59.080 --> 00:25:07.080 the ways the excitotoxic process is one of the things that turns on nitric oxide production 00:25:07.080 --> 00:25:15.080 going ahead and killing the cell. That's why the excited state is toxic, largely because 00:25:15.080 --> 00:25:19.080 of the production of nitric oxide. 00:25:19.080 --> 00:25:24.080 Okay, now I guess methylene blue is not an FDA-controlled substance or anything. I think 00:25:24.080 --> 00:25:29.080 it's fairly widely available. It's just a dye, isn't it? I think typically it's known 00:25:29.080 --> 00:25:32.080 as a dye. I know it's a tissue stain. 00:25:32.080 --> 00:25:39.080 And fish stores use it. I'm not sure how they use it, but it's for sterilizing aquariums 00:25:39.080 --> 00:25:48.080 or something. And fish farmers use it to cure various fish infections. 00:25:48.080 --> 00:25:54.080 Okay, well, people listening perhaps might want to start looking up methylene blue and 00:25:54.080 --> 00:26:03.080 its implications in the treatment and/or prevention of different degenerative conditions. So extremely 00:26:03.080 --> 00:26:09.080 cheap, I'm sure, not all patented, not controlled. And if there's some good studies coming out 00:26:09.080 --> 00:26:14.080 showing methylene blue's positive effects in blocking nitric oxide, I think that could 00:26:14.080 --> 00:26:20.080 be well worth people looking at as an alternative to many of the drugs that people might be 00:26:20.080 --> 00:26:22.080 using for different conditions. 00:26:22.080 --> 00:26:23.080 Okay. 00:26:23.080 --> 00:26:31.080 I've counted about six different ways that methylene blue stops or blocks the production 00:26:31.080 --> 00:26:34.080 of nitric oxide. 00:26:34.080 --> 00:26:40.080 Okay, go on. Do you want to share them? 00:26:40.080 --> 00:26:53.080 No. The excitotoxic thing was one, preventing excess polymerization of the microtubules. 00:26:53.080 --> 00:27:04.080 Another, probably increasing progesterone production, inhibiting estrogen production. 00:27:04.080 --> 00:27:13.080 But probably the most important thing people should do is to start being critical about 00:27:13.080 --> 00:27:21.080 the tremendous amount of propaganda selling the idea that people should eat more arginine 00:27:21.080 --> 00:27:24.080 to increase their nitric oxide production. 00:27:24.080 --> 00:27:33.080 Wow. Wow. Yeah. I don't know, it always amazes me how this stuff actually comes into circulation 00:27:33.080 --> 00:27:44.080 as "common knowledge" and how easily influenced the media is by Big Pharma. Anyway, not to 00:27:44.080 --> 00:27:49.080 go on too much about that, because we could probably go on forever about how Big Pharma 00:27:49.080 --> 00:27:53.080 have their hooks all over. Anyway, it's coming up for 7.30. I've seen the lights flashing 00:27:53.080 --> 00:27:56.080 a couple of times, and I don't know if anyone's on the line at the moment. No shaking his 00:27:56.080 --> 00:27:58.080 head, must have gone off. Okay, no problem. 00:27:58.080 --> 00:28:02.080 You're listening to Ask Your Ob-Docs, we're on KMED Gallup 91.1 FM. From now until the 00:28:02.080 --> 00:28:06.080 end of the show at 8 o'clock, you're invited to call in any questions, either related or 00:28:06.080 --> 00:28:12.080 unrelated to this month's subject of nitric oxide and how to control its damaging effects. 00:28:12.080 --> 00:28:19.080 Dr. Raymond Peat is with us in the studio. He's a pretty foremost authority on lots of 00:28:19.080 --> 00:28:27.080 different subjects surrounding hormones and aging and all the interactions thereon. He's 00:28:27.080 --> 00:28:33.080 with us in the show. We have a caller on the line already, look at that. Okay, caller, 00:28:33.080 --> 00:28:35.080 you're on the air, and where are you from? 00:28:35.080 --> 00:28:50.080 I'm from Southern Humboldt here. Okay. Yeah. John, I wanted to know if all of the estrogen 00:28:50.080 --> 00:28:56.080 imitators that are around us in the environment that we've created for ourselves to live in 00:28:56.080 --> 00:29:00.080 are also something that'll put us at risk? 00:29:00.080 --> 00:29:03.080 Very much, very much so, yeah. That's it. 00:29:03.080 --> 00:29:08.080 I think I've seen that bisphenol A activates nitric oxide production. 00:29:08.080 --> 00:29:16.080 There you go, and that's an estrogen promoter, or mimic. Yeah, okay, so environmental estrogens 00:29:16.080 --> 00:29:22.080 very much have a negative impact on our health, many of which have come from petrochemical 00:29:22.080 --> 00:29:28.080 industry, plastics industry, etc. Dr. Peat, what do you think some of the most damaging 00:29:28.080 --> 00:29:32.080 environmental estrogens that you know of that are... 00:29:32.080 --> 00:29:40.080 Oh, the natural estrogen is... It's damaging enough. 00:29:40.080 --> 00:29:48.080 Yeah, it's through the sewage, it's getting into the rivers, and for the environment, 00:29:48.080 --> 00:29:56.080 I think that the natural estrogen and the birth control estrogens that are many times 00:29:56.080 --> 00:30:05.080 stronger than natural estrogen are showing up in all of the downstream waterways that 00:30:05.080 --> 00:30:09.080 receive sewage. So wastewater management does not selectively 00:30:09.080 --> 00:30:15.080 remove hormones from the water, then, are you saying? It's found... I wonder if it's 00:30:15.080 --> 00:30:20.080 reasonable to posit that there is detectable amounts in drinking water, even. 00:30:20.080 --> 00:30:26.080 Well, as a sewer board person, I can tell you that one of the ways that they tell whether 00:30:26.080 --> 00:30:32.080 water is coming from a sewage system or from nature is they look for caffeine, that's considered 00:30:32.080 --> 00:30:37.080 one of the chemicals that makes it through and is a marker for sewage as opposed to animal 00:30:37.080 --> 00:30:41.080 waste or whatever. So yeah, a lot of those chemicals do make it through. 00:30:41.080 --> 00:30:43.080 Okay, did we have any other questions? 00:30:43.080 --> 00:30:55.080 Oh yeah, the other part of my question was, is there a plant or an herb that actually 00:30:55.080 --> 00:31:01.080 produces or mimics methylene blue that you can ingest instead of... 00:31:01.080 --> 00:31:13.080 Oh, I've been looking around at various molecules and it was a precursor for many of the drugs, 00:31:13.080 --> 00:31:22.080 the tricyclic antidepressants and tricyclic antihistamines and anti-inflammatories, I 00:31:22.080 --> 00:31:30.080 think all grew out of the dye industry that methylene blue was one of the very first examples 00:31:30.080 --> 00:31:42.080 of, but it's a three ring molecule and that seems probably because it's structurally roughly 00:31:42.080 --> 00:31:50.080 the same size and shape as the steroid hormones, it probably can get into many of the places 00:31:50.080 --> 00:32:01.080 that our natural steroids act. So I've looked around at plants that make analogous things. 00:32:01.080 --> 00:32:10.080 The tetracyclines have many of the same anti-inflammatory effects, I suspect they're also working against 00:32:10.080 --> 00:32:16.080 nitric oxide, they just have one extra ring but in a very similar arrangement. 00:32:16.080 --> 00:32:24.080 And vitamin K and vitamin E are even analogous in some ways. 00:32:24.080 --> 00:32:40.080 Lopacho, a chemical from a South American tree, it's a dye that has many of the anti-inflammatory, 00:32:40.080 --> 00:32:44.080 anti-cancer properties of methylene blue. Spell that. 00:32:44.080 --> 00:32:58.080 Lopacho is a tabubui, so T-A-B-E-B-U-I-A, tabubui, and impetigenosa, it's a South American, 00:32:58.080 --> 00:33:04.080 tall South American hardwood, but it's used extensively for cancer as Dr. Peat mentioned, 00:33:04.080 --> 00:33:06.080 they call it pau de arco. 00:33:06.080 --> 00:33:15.080 Recently people are talking about a thing, an Asian herb, I think one of the names is 00:33:15.080 --> 00:33:25.080 black cumin, but it contains thymoquinone and the quinones are I think the essential 00:33:25.080 --> 00:33:38.080 model of the protective pro-oxidant stabilizing chemical and thymoquinone is considered to 00:33:38.080 --> 00:33:46.080 be a very powerful anti-inflammatory and I suspect that it'll turn out to be acting against 00:33:46.080 --> 00:33:48.080 excess nitric oxide. 00:33:48.080 --> 00:33:52.080 So it's a free radical quencher again, isn't it, the quinones? 00:33:52.080 --> 00:34:00.080 Yeah, that's just one of their many, they seem to activate the right kind of oxidation 00:34:00.080 --> 00:34:02.080 while quenching the bad kind. 00:34:02.080 --> 00:34:03.080 Okay, very good. 00:34:03.080 --> 00:34:05.080 All right, well thank you very much. 00:34:05.080 --> 00:34:08.080 Yeah, thanks for your caller, caller. We have three callers on the lines here, so let's 00:34:08.080 --> 00:34:12.080 get them one after the other. Caller, you're on the air, where are you from? 00:34:12.080 --> 00:34:13.080 Me? 00:34:13.080 --> 00:34:15.080 Hi, you're on the air, where are you from? 00:34:15.080 --> 00:34:16.080 Hi, Arcata. 00:34:16.080 --> 00:34:19.080 Arcata, okay. Go ahead, what's your question? 00:34:19.080 --> 00:34:22.080 Thanks, I've been listening to your show for a good four years or so. 00:34:22.080 --> 00:34:28.080 A couple of quick review questions from the past that I've been wondering about for a 00:34:28.080 --> 00:34:35.080 long time. It was mentioned some time ago about a nutrient I believe that could help 00:34:35.080 --> 00:34:40.080 remediate or, you know, fix the earlobe crease. Does that ring any bell? 00:34:40.080 --> 00:34:42.080 What was the last thing you said? 00:34:42.080 --> 00:34:43.080 Earlobe crease? 00:34:43.080 --> 00:34:44.080 Oh, the earlobe. 00:34:44.080 --> 00:34:45.080 Earlobe crease, yeah. 00:34:45.080 --> 00:34:47.080 That's a thyroid deficiency, isn't it? 00:34:47.080 --> 00:34:51.080 Yeah, I think it is mainly a thyroid deficiency. 00:34:51.080 --> 00:34:58.080 Okay, and did I hear at the time a simple recommendation for correction of that? Was 00:34:58.080 --> 00:35:03.080 there a nutrient or is that a much more complex matter to address? 00:35:03.080 --> 00:35:12.080 I think the main thing causing hypothyroidism in so many people is an excess of the polyunsaturated 00:35:12.080 --> 00:35:20.080 fatty acids because they're able to block the production of thyroid, its transport and 00:35:20.080 --> 00:35:29.080 its action. So, they're very capable of antagonizing thyroid function. 00:35:29.080 --> 00:35:36.080 So, to avoid all the nuts and seeds that contain liquid oils in them, so nuts and seeds are 00:35:36.080 --> 00:35:41.080 principally the kind of polyunsaturated sources and obviously there are other polyunsaturated 00:35:41.080 --> 00:35:47.080 yet commonly available in food that you should definitely avoid. So, any of the liquid oils, 00:35:47.080 --> 00:35:48.080 obviously. 00:35:48.080 --> 00:35:50.080 What about like coconut oil? Is that for? 00:35:50.080 --> 00:35:56.080 Coconut oil is saturated, so that's good. Dr. Peat's always recommending coconut oil 00:35:56.080 --> 00:36:02.080 and butter as being the two saturated sources of fat. That should be the most consumed. 00:36:02.080 --> 00:36:07.080 And then to avoid all the liquids, liquid polyunsaturates, obviously fish oil being 00:36:07.080 --> 00:36:08.080 the worst. 00:36:08.080 --> 00:36:12.080 Okay. Whoa, like cod liver oil? 00:36:12.080 --> 00:36:17.080 That too, but I think, Dr. Peat, don't you say that the vitamin content in cod liver 00:36:17.080 --> 00:36:18.080 oil... 00:36:18.080 --> 00:36:24.080 Oh, yeah, if you don't have any better source, cod liver oil is a great source of vitamin 00:36:24.080 --> 00:36:25.080 D. 00:36:25.080 --> 00:36:26.080 Yeah. 00:36:26.080 --> 00:36:28.080 But it's better to get sunlight. 00:36:28.080 --> 00:36:29.080 Yeah. 00:36:29.080 --> 00:36:30.080 Okay. 00:36:30.080 --> 00:36:33.080 Can I have one quick other question? 00:36:33.080 --> 00:36:34.080 Go ahead. 00:36:35.080 --> 00:36:40.080 There was something that came up about eating carrots and I don't know what the term would 00:36:40.080 --> 00:36:46.080 be, but I want to say like an astringent or a cleaning or a purifying or... 00:36:46.080 --> 00:36:47.080 An antiseptic, yeah. 00:36:47.080 --> 00:36:53.080 ...a helpful aspect of eating carrots. It was recommended that carrots be cut diagonally 00:36:53.080 --> 00:36:59.080 as a juicer and a cook, I guess, of my own food. I thought that was a bit peculiar and 00:36:59.080 --> 00:37:01.080 I wondered if that could be elaborated upon. 00:37:01.080 --> 00:37:07.080 I think Dr. Peat's always mentioned that grated carrots to increase the surface area is the 00:37:07.080 --> 00:37:12.080 mechanism that's preferred and that's basically is a antiseptic, if you like, for the gut, 00:37:12.080 --> 00:37:19.080 removing excess estrogen and other waste products and it's undigested, so has a pretty good 00:37:19.080 --> 00:37:22.080 action in the gut without physically being changed. 00:37:22.080 --> 00:37:28.080 But like chewing it is not enough to enhance the surface area, like breaking it down? 00:37:28.080 --> 00:37:33.080 Well, not the same because ultimately when you grate the product in a grater then you 00:37:33.080 --> 00:37:37.080 obviously have a big surface area then and whatever you chew that up from then is going 00:37:37.080 --> 00:37:42.080 to increase it still. 00:37:42.080 --> 00:37:50.080 The juice does contain a lot of good things, but if you throw away the fibre you're losing 00:37:50.080 --> 00:37:57.080 the most important thing for stimulating and cleaning the intestine. 00:37:57.080 --> 00:37:59.080 Alright, cool. Thanks for your help. 00:37:59.080 --> 00:38:02.080 Thanks for your call. I've got a couple more callers here, so let's take the next caller. 00:38:02.080 --> 00:38:05.080 Where are you from? 00:38:05.080 --> 00:38:09.080 Hello, caller. You're on the air. Where are you from? 00:38:09.080 --> 00:38:13.080 Was on the air. Engineer, is he on the air or on? 00:38:13.080 --> 00:38:16.080 I guess not. Caller, 321. Actually, the other caller hung up too. 00:38:16.080 --> 00:38:17.080 Hello? 00:38:17.080 --> 00:38:18.080 Oh, there you go. 00:38:18.080 --> 00:38:21.080 Oh, I'm here. Yeah. 00:38:21.080 --> 00:38:24.080 Where are you from, caller? 00:38:24.080 --> 00:38:26.080 Excuse me, I'm from Southern Humboldt. 00:38:26.080 --> 00:38:27.080 Okay, go ahead. What's your question? 00:38:27.080 --> 00:38:32.080 Well, I've got a couple of questions. First, did you say that L-Arginine was bad? 00:38:32.080 --> 00:38:36.080 I've heard that that was supposed to be good for you, but I'm not sure what it's supposed to do. 00:38:36.080 --> 00:38:39.080 Okay, Dr. Peat, Arginine, you mentioned it a moment ago. 00:38:39.080 --> 00:38:41.080 Yeah, I've been noticing... 00:38:41.080 --> 00:38:44.080 And is there a difference between Arginine and L-Arginine? 00:38:44.080 --> 00:38:54.080 Yeah, the internet is just swamped with advertisements for ways to supplement Arginine. 00:38:54.080 --> 00:39:02.080 L-Arginine is just the natural amino acid, but if you get more than you need, 00:39:02.080 --> 00:39:08.080 it will increase your tendency to overproduce nitric oxide, 00:39:08.080 --> 00:39:19.080 and too much tryptophan happens to boost that, possibly by increasing serotonin, 00:39:19.080 --> 00:39:24.080 but it's very important to keep your amino acids in a good balance, 00:39:24.080 --> 00:39:31.080 especially avoiding too much cysteine, tryptophan, methionine, and Arginine. 00:39:31.080 --> 00:39:35.080 So you don't recommend taking an L-Arginine supplement? 00:39:35.080 --> 00:39:38.080 No, I think it's very dangerous. 00:39:38.080 --> 00:39:40.080 Oh, okay. 00:39:40.080 --> 00:39:50.080 Now, did you say that Viagra is bad for you because it's made out of this nitric oxide stuff? 00:39:50.080 --> 00:40:05.080 It inhibits an enzyme that is supposed to inactivate a substance made by the production of nitric oxide. 00:40:05.080 --> 00:40:12.080 Nitric oxide starts a chain reaction, and Viagra keeps that chain reaction going, 00:40:12.080 --> 00:40:20.080 and in the process it ends up systemically increasing not only the effect of nitric oxide, 00:40:20.080 --> 00:40:26.080 but even in some situations the level of nitric oxide. 00:40:26.080 --> 00:40:38.080 So it probably is increasing the aging process basically in brain, heart, pancreas, 00:40:38.080 --> 00:40:40.080 everywhere you get an excess of nitric oxide. 00:40:40.080 --> 00:40:43.080 But they say having sex is good for you. 00:40:43.080 --> 00:40:46.080 If you can't have sex, that's not so great either. 00:40:46.080 --> 00:40:52.080 I mean, is it a matter of moderation and not using it too often? 00:40:52.080 --> 00:40:54.080 Can it be okay if you use some of it? 00:40:54.080 --> 00:40:56.080 I mean, I don't know. I'm not a man. 00:40:56.080 --> 00:41:04.080 Well, it's one of the essential amino acids, and so if you eat any good high-quality protein, 00:41:04.080 --> 00:41:10.080 even potatoes, milk, cheese, you're going to get all of the arginine you need. 00:41:10.080 --> 00:41:13.080 No, no, I'm talking about Viagra now. 00:41:13.080 --> 00:41:14.080 Oh, Viagra. 00:41:14.080 --> 00:41:20.080 Yeah, yeah. I mean, is that like totally bad, or is it okay to have some of it? 00:41:20.080 --> 00:41:25.080 Because I'm saying if that improves the sexual function of an older man, 00:41:25.080 --> 00:41:30.080 then sexual function is supposed to be a good thing. 00:41:30.080 --> 00:41:34.080 I mean, is there a balance there, or do you think it's totally bad? 00:41:34.080 --> 00:41:40.080 I think it would be better to work on the actual physiological problem, 00:41:40.080 --> 00:41:43.080 improving natural circulation. 00:41:43.080 --> 00:41:52.080 And, for example, restoring good thyroid function will often increase libido and potency. 00:41:52.080 --> 00:42:01.080 Now, Dr. Peat, I remember now some time ago you also mentioning pregnenolone and/or progesterone as being very positive. 00:42:01.080 --> 00:42:11.080 I mean, in the past, it always talked about progesterone potentially being slightly sedative and maybe decreasing. 00:42:11.080 --> 00:42:13.080 I think now you have said this, let me quote you. 00:42:13.080 --> 00:42:21.080 I think you said decreasing penis size, but it does not block the vasodilatory ability, 00:42:21.080 --> 00:42:26.080 and so therefore actually does promote and enable erection, 00:42:26.080 --> 00:42:29.080 and actually is a reasonably safe way of doing that in males. 00:42:29.080 --> 00:42:32.080 Well, what about testosterone? 00:42:32.080 --> 00:42:34.080 One thing at a time, huh? 00:42:34.080 --> 00:42:43.080 Aging men have decreased amounts of testosterone and progesterone and increasing amounts of estrogen, 00:42:43.080 --> 00:42:52.080 and that increased estrogen and the decreased amounts of the protective steroids, 00:42:52.080 --> 00:42:58.080 I think, will increase the tendency to have erectile problems. 00:42:58.080 --> 00:43:10.080 And one of the really odd side effects of increased nitric oxide is that it decreases the ability to make testosterone. 00:43:10.080 --> 00:43:21.080 And, at least in women, it lowers the progesterone synthesis, but those are synthesized very similarly. 00:43:21.080 --> 00:43:33.080 So I think in both men and women, nitric oxide is opposing and lowering those protective steroids while increasing estrogen. 00:43:33.080 --> 00:43:37.080 Well, what about Cialis? Is that just the same as Viagra? 00:43:37.080 --> 00:43:41.080 There are several products on the market that are supposed to help men with their erections. 00:43:41.080 --> 00:43:43.080 It's another version. 00:43:43.080 --> 00:43:45.080 Are they all the same? 00:43:45.080 --> 00:43:47.080 Yeah, pretty much. 00:43:47.080 --> 00:43:51.080 All right, well, thank you. 00:43:51.080 --> 00:43:53.080 Yeah, thanks for your call. 00:43:53.080 --> 00:43:58.080 Okay, Dr. Peat, I wanted to ask you some more questions about nitric oxide 00:43:58.080 --> 00:44:02.080 and/or some of the articles I've seen about it promoting cancer. 00:44:02.080 --> 00:44:07.080 What are your thoughts on the cancer-promoting effects of nitric oxide? 00:44:07.080 --> 00:44:17.080 I think it's one of the central factors in keeping cancer going, so turning it off. 00:44:17.080 --> 00:44:22.080 You don't necessarily think it's a promoter, then? 00:44:22.080 --> 00:44:27.080 Oh, yeah, it is a definite promoter of cancer growth and metastasis. 00:44:27.080 --> 00:44:33.080 Many publications are now recognizing that, breast cancer, prostate cancer, 00:44:33.080 --> 00:44:44.080 and probably every cancer will probably eventually be discovered to respond badly to nitric oxide. 00:44:44.080 --> 00:44:46.080 Okay. 00:44:46.080 --> 00:44:59.080 The function of anything interfering with respiration, that's where the Varberg hypothesis was 00:44:59.080 --> 00:45:10.080 that simply shifting away from oxygen as the energy source to being able to produce too much lactic acid, 00:45:10.080 --> 00:45:16.080 even when there's oxygen because the cell has lost its mitochondrial function, 00:45:16.080 --> 00:45:26.080 nitric oxide and carbon monoxide are both able to knock out the mitochondrial function 00:45:26.080 --> 00:45:30.080 and imitate the cancer metabolism. 00:45:30.080 --> 00:45:44.080 There are several recent publications showing that the Varberg cancer metabolism is created by nitric oxide excess 00:45:44.080 --> 00:45:52.080 and it's turned off by methylene blue simply by turning off the production of nitric oxide. 00:45:52.080 --> 00:45:57.080 Okay. You're listening to Ask Your Abdoctor on KMUD Galbraithville, 91.1 FM. 00:45:57.080 --> 00:46:03.080 From now to the end of the show at 8 o'clock, we're pleased to have Dr. Raymond Peat joining us on the show. 00:46:03.080 --> 00:46:05.080 The number here is 923 3911. 00:46:05.080 --> 00:46:11.080 Hopefully, outside the area, there's a toll-free number, which is 1-800-KMUD-RAD. 00:46:11.080 --> 00:46:17.080 So, Dr. Peat, again, I had a question on my mind during this week 00:46:17.080 --> 00:46:23.080 that reading different research on different diseases and apart from that, 00:46:23.080 --> 00:46:34.080 knowing that some individuals are just inherently more able to enjoy good health seemingly against all odds, 00:46:34.080 --> 00:46:42.080 have you any understanding of why some individuals, for example, are immune to HIV? 00:46:42.080 --> 00:46:48.080 Why some individuals mount a successful response against hepatitis? 00:46:48.080 --> 00:46:57.080 Some individuals just have an innate immunity which enables them to overcome what it is they come into contact with 00:46:57.080 --> 00:46:59.080 and they don't suffer from it. 00:46:59.080 --> 00:47:05.080 Do you think there's any connection between anything that you've read that you know about that you might be able to explain that from? 00:47:05.080 --> 00:47:16.080 Yes, there are new ideas about the whole functioning of the immune system that have been coming up in the last 20 years. 00:47:16.080 --> 00:47:24.080 Jamie Cunliffe and Polly Mattson are the leading figures in that view of the immune system. 00:47:24.080 --> 00:47:36.080 I see it as imagining the body as an ecosystem which is simply so strong in some people 00:47:36.080 --> 00:47:49.080 at maintaining its own organization and stability that when something extraneous like a bacterium or a virus 00:47:49.080 --> 00:48:04.080 or a cancer cell happens to invade it, the situation is so tightly organized in favor of maintaining the host organism 00:48:04.080 --> 00:48:08.080 that the invader can't find a place. 00:48:08.080 --> 00:48:16.080 The niches are all occupied doing business with the owner of the property. 00:48:16.080 --> 00:48:18.080 There's simply no place to camp out. 00:48:18.080 --> 00:48:21.080 Like the strongman in the house, no one can invade it. 00:48:21.080 --> 00:48:32.080 Yes, and I don't see it as a killing of the invader but simply as using up all of the electron space productively 00:48:32.080 --> 00:48:40.080 so that invaders can't do strange things with it like turning sugar into lactic acid. 00:48:40.080 --> 00:48:53.080 Okay, I'd love to be able to get into the subject that I saw posted last thing today and that was to quote what I've said before many times 00:48:53.080 --> 00:48:57.080 and I think it's been repeated through generations that you are what you eat. 00:48:57.080 --> 00:49:00.080 I think I'd love to get into that subject with you next month. 00:49:00.080 --> 00:49:07.080 I think we have another call on it anyway but I'd love to get into that subject next month and just show that what we hear sometimes 00:49:07.080 --> 00:49:14.080 really does mean a lot more than we take for granted and that actually a lot of the things that are passed down from old generations to now 00:49:14.080 --> 00:49:22.080 really have their roots in fundamental science and that science now is at last being able to bear that out. 00:49:22.080 --> 00:49:26.080 So let me just get this other caller on the air and then we'll carry on. 00:49:26.080 --> 00:49:28.080 Actually, two simple questions coming through me. 00:49:28.080 --> 00:49:29.080 Okay. 00:49:29.080 --> 00:49:34.080 First one is MSM and does it have an influence on male or female libido? 00:49:34.080 --> 00:49:37.080 Okay, dogspeed, methylene sulfmethane is it? 00:49:37.080 --> 00:49:38.080 I believe. 00:49:38.080 --> 00:49:44.080 I'm very cautious about it. 00:49:44.080 --> 00:49:58.080 The dimethyl sulfide I think has its uses but I'm not sure that there's anything really fully safe with MSM. 00:49:58.080 --> 00:50:04.080 And what about DCA or dichloroacetate for cancers? 00:50:04.080 --> 00:50:15.080 That happens to be very similar to methylene blue in the way it is essentially non-toxic in moderate amounts. 00:50:15.080 --> 00:50:23.080 People are now getting as much as 10 or 12 grams of it per day intravenously and feeling great. 00:50:23.080 --> 00:50:31.080 But what it does is restore the productive oxidation of glucose, 00:50:31.080 --> 00:50:38.080 getting the electrons to go all the way from glucose to form carbon dioxide, 00:50:38.080 --> 00:50:43.080 pretty much what methylene blue is doing in different situations. 00:50:43.080 --> 00:50:57.080 But the DCA is reversing the cancer metabolism or the so-called Farberg metabolism the same way that methylene blue does. 00:50:57.080 --> 00:51:14.080 So I see it as a very important way of making up for the toxic effects of nitric oxide, endotoxin, free radical, fat oxidation and so on. 00:51:14.080 --> 00:51:17.080 And you've spoken of antioxidants that are too strong. 00:51:17.080 --> 00:51:21.080 Could you maybe give a spectrum of antioxidants and say is ALA too strong 00:51:21.080 --> 00:51:28.080 or what is the strongest antioxidant you would recommend and THC in that spectrum as well? 00:51:28.080 --> 00:51:40.080 Vitamin E and ascorbic acid in the right proportion and the right situation are very safe and constructive. 00:51:40.080 --> 00:51:57.080 Alpha-oleic acid is pretty safe, but I would be very cautious with the acetylcysteine. 00:51:57.080 --> 00:52:03.080 I think large amounts of it can push the balance in the wrong direction. 00:52:03.080 --> 00:52:16.080 Okay. All right. Dr. Peat, I had a question actually from a person who wrote to me who said that they were unable to call in because they were outside the country. 00:52:16.080 --> 00:52:20.080 And I think by the time I responded to them to ask them what country they were in, it was probably already too late. 00:52:20.080 --> 00:52:26.080 And I have come across this with other people anyway in our own practice and working with you, 00:52:26.080 --> 00:52:30.080 I think I understand the situation, but I'd like to hear it from you. 00:52:30.080 --> 00:52:40.080 It was particularly a woman who said that she had hypothyroidism symptoms including depression, weight gain, cold hands and feet, dry hair and skin. 00:52:40.080 --> 00:52:48.080 Her TSH, her thyroid stimulating hormone, was 1.6, which wasn't super high, but I know you like it to be as close to zero as possible. 00:52:48.080 --> 00:52:52.080 And her T3 was 3.5. She said she used to take armothyroid. 00:52:52.080 --> 00:52:56.080 She was prescribed this by a doctor and it helped with symptoms for a few months. 00:52:56.080 --> 00:53:05.080 And she said that when she tried to supplement with T3 or a T3 and T4 combination, she developed anxiety and tachycardia. 00:53:05.080 --> 00:53:13.080 She said she's experimented with doses as small even as 1 milligram of T3 and she said it would send her into a hyperthyroid type state. 00:53:13.080 --> 00:53:20.080 I think that's kind of anxiety and palpitations. It may be an adrenaline thing. 00:53:20.080 --> 00:53:24.080 But she said is there anything that she could do to better tolerate thyroid supplementation? 00:53:24.080 --> 00:53:28.080 She is currently taking zinc gluconate, vitamin D, vitamin K. 00:53:28.080 --> 00:53:32.080 She's using 4,000 IU of vitamin D. 00:53:32.080 --> 00:53:38.080 She's using Progestin, the second half of her menstrual cycle, aspirin, magnesium and calcium. 00:53:38.080 --> 00:53:40.080 She also eats liver weekly. 00:53:40.080 --> 00:53:45.080 What do you think might cause that in a person who previously might have used thyroid 00:53:45.080 --> 00:53:51.080 and then suddenly becomes what they call sensitive to it and unable to use it? 00:53:51.080 --> 00:53:54.080 Sometimes I think it's that the product has changed. 00:53:54.080 --> 00:54:02.080 European forms of thyroid supplement seem to be very unpredictable. 00:54:02.080 --> 00:54:13.080 But if it's for sure the same product, then usually a magnesium deficiency can cause exactly those symptoms 00:54:13.080 --> 00:54:20.080 because the thyroid makes your cells able to use magnesium and so take it up. 00:54:20.080 --> 00:54:31.080 But a big organ like your skeletal muscles and bones can take up so much from your blood 00:54:31.080 --> 00:54:39.080 that your brain and heart and such have trouble getting the magnesium they need to respond to the thyroid. 00:54:39.080 --> 00:54:45.080 And then you get an exaggerated stress and adrenaline reaction. 00:54:45.080 --> 00:54:50.080 And low cholesterol is another limiting factor. 00:54:50.080 --> 00:54:57.080 If you have very low cholesterol, you can't respond to increasing your thyroid 00:54:57.080 --> 00:55:07.080 because one of the basic functions of thyroid is to turn cholesterol into progesterone, pregnenolone and DHEA. 00:55:07.080 --> 00:55:13.080 Okay. So what kind of dose of magnesium would you think for that kind of person would be suitable? 00:55:13.080 --> 00:55:28.080 About 100 milligrams at a time as you take say one or two micrograms of cytomel or senomel. 00:55:28.080 --> 00:55:39.080 100 micrograms will be plenty for the first two or three hours of responding to one or two micrograms. 00:55:39.080 --> 00:55:46.080 Okay. I looked earlier on as I was doing some searching around. 00:55:46.080 --> 00:55:52.080 I saw that the main principle sources that seemed of magnesium were nuts, nuts and seeds. 00:55:52.080 --> 00:55:57.080 I think there were small amounts in soy. 00:55:57.080 --> 00:56:02.080 But I think principally what would you recommend as a good magnesium source? 00:56:02.080 --> 00:56:16.080 Fruit juices and coffee I think are if you want a really intense source, you can boil leaves like kale or beet greens or something just for two or three minutes. 00:56:16.080 --> 00:56:23.080 And the green water that comes out quickly is very concentrated in magnesium and calcium. 00:56:23.080 --> 00:56:25.080 Okay. Excellent. 00:56:25.080 --> 00:56:37.080 That's a very pretty safe supplement. Coffee and fruit juices are practical and something you can do every day. 00:56:37.080 --> 00:56:45.080 Okay. All right. But like I said, perhaps next month if you're available, I'd love to look into that new research. 00:56:45.080 --> 00:56:50.080 Well, actually I think it was brought out in mid-1960s by that Korean. 00:56:50.080 --> 00:56:57.080 It sounded very interesting about the third circulatory system in the body and actually that you are what you eat 00:56:57.080 --> 00:57:06.080 because there is a pretty intimate interaction between food products and our own DNA. 00:57:06.080 --> 00:57:10.080 They can be switched on and off and regulated. That sounded pretty fascinating. 00:57:10.080 --> 00:57:22.080 Yeah. There's a German group that has been doing this for about 15 years now looking at the DNA from our foods getting incorporated into our own DNA. 00:57:22.080 --> 00:57:23.080 Yeah. 00:57:23.080 --> 00:57:29.080 And some biologists have been theorizing about this for the last hundred years. 00:57:29.080 --> 00:57:46.080 Carl Lindgren was someone who reviewed the topic about 50 years ago showing good evidence that organisms all across the spectrum are sharing nucleic acid. 00:57:46.080 --> 00:58:01.080 Pollen, for example, when you ingest pollen that's blowing in the air, some of the DNA is probably actually getting incorporated into our chromosomes. 00:58:01.080 --> 00:58:06.080 Yeah. Well, listen, I want to let people know how to find out more about you if they've not heard about you. 00:58:06.080 --> 00:58:10.080 So thanks so much for giving your time for the show this evening, Dr. Peat. 00:58:10.080 --> 00:58:11.080 Okay. Thank you. 00:58:11.080 --> 00:58:17.080 Okay. So for people who've listened to the show or maybe haven't heard of Dr. Peat before, he's got a wealth of information on his website. 00:58:17.080 --> 00:58:20.080 It's freely accessible. It's fully referenced scientific material. 00:58:20.080 --> 00:58:33.080 It's not just made up. It's fully referenced and there's plenty of articles both on PubMed and other medical research sites to validate what Dr. Peat is saying. 00:58:33.080 --> 00:58:44.080 It's the science that provides the answers and it's not what we know in the mainstream media which is told to us by pharmaceutical companies and other vested interests. 00:58:44.080 --> 00:58:52.080 But the scientists that are interested in humanitarian causes are definitely finding lots of very novel ways of treating disease. 00:58:52.080 --> 00:58:59.080 So don't just think that what you see on the television or read in the newspapers is the only way that you can get yourself healthy. 00:58:59.080 --> 00:59:04.080 So Raymond Peat's website is www.rayPeat.com. 00:59:04.080 --> 00:59:16.080 It's got lots of articles and for those of you who'd like to get in contact with us during regular business hours, we can be reached on 1-888-WBM-ERB for further information. 00:59:16.080 --> 00:59:20.080 So until December's show, thanks so much for joining. 00:59:21.080 --> 00:59:31.080 [Music] 00:59:31.080 --> 00:59:36.080 >> Came out thanks Jessica Baker of Jade Dragon Acupuncture for her support of Redwood Community Radio. 00:59:36.080 --> 00:59:44.080 Practicing and teaching Chinese medicine, herbalism and aromatherapy, Jessica is available for conferences, workshops and private consultations. 00:59:44.080 --> 00:59:56.080 Located at 607 F Street in Arcata, Jade Dragon Acupuncture can be reached at 822-4300 or online at jadedragonacupuncture.com. 00:59:56.080 --> 00:59:58.080 And support for KMUD comes from...