WEBVTT 00:00:00.000 --> 00:00:26.500 [Music] 00:00:26.500 --> 00:00:30.900 Welcome to Ask Your Herb Doctor. My name is Andrew Murray. My name is Sarah 00:00:30.900 --> 00:00:34.580 Johanneson Murray. We both trained in England and graduated there with a 00:00:34.580 --> 00:00:38.220 degree in herbal medicine and clients consult with us regarding their health 00:00:38.220 --> 00:00:42.300 issues and we recommend personalized advice in nutrition, supplements, herbs, 00:00:42.300 --> 00:00:48.880 diet, lifestyle. We can be reached toll-free at 1-888-WBM-HERB or on the 00:00:48.880 --> 00:00:56.180 web at www.westernbotanicalmedicine.com. So on tonight's show we're very welcome 00:00:56.180 --> 00:01:00.700 again to have Dr. Raymond Peat joining us to give us the answers to his wisdom, 00:01:00.700 --> 00:01:05.700 from his wisdom, explaining those things that perhaps not what we normally would 00:01:05.700 --> 00:01:09.620 hear in the mainstream, almost certainly not what we would hear in the mainstream, 00:01:09.620 --> 00:01:15.340 but nonetheless very well researched, plenty of information there that people 00:01:15.340 --> 00:01:21.820 can also look at after the show either by visiting Dr. Peat's website at 00:01:21.820 --> 00:01:27.580 www.raypeat.com. Plenty of articles fully referenced and like I said most of the 00:01:27.580 --> 00:01:31.900 subjects there will have advice and research that you probably would not 00:01:31.900 --> 00:01:34.800 have heard of elsewhere. So we're always very pleased to have Dr. Peat on the 00:01:34.800 --> 00:01:40.460 show. Thanks for your time Dr. Peat. For people who perhaps have never heard you 00:01:40.460 --> 00:01:45.740 or listened to the show, would you give people your background, your academic 00:01:45.740 --> 00:01:50.740 and professional background before we get into the subject? After getting 00:01:50.740 --> 00:01:58.180 a master's degree in humanities at University of Oregon, I came back in 1968 00:01:58.180 --> 00:02:09.220 to 72 for a biology PhD concentrating on reproductive physiology. The 00:02:09.220 --> 00:02:17.460 hormones involved in reproduction are involved in everything relating to life 00:02:17.460 --> 00:02:27.700 and brain development was one of my second themes of research. So brain 00:02:27.700 --> 00:02:32.700 development, aging and the hormones involved in that gradual decline 00:02:32.700 --> 00:02:37.460 in good health. Okay so just for people that are listening to the show that we 00:02:37.460 --> 00:02:42.100 will be taking calls from 7.30 till the end of the show either related to this 00:02:42.100 --> 00:02:45.980 month's continuing topic of nitric 00:02:45.980 --> 00:02:51.740 oxide. I wanted to get a little bit into the subject of iodine as an opener for 00:02:51.740 --> 00:02:56.740 the show for people thinking about supplementing with iodine and also open 00:02:56.740 --> 00:03:00.540 up a little bit about the Zika virus that's really catching media attention 00:03:00.540 --> 00:03:08.740 here. I know there's certain, what do you want to say, authoritative reasons for it and 00:03:08.740 --> 00:03:12.220 there are other supposedly conspiracy theories that we can call them 00:03:12.220 --> 00:03:16.020 conspiracies but I think some of the merits of the conspiracies are worth 00:03:16.020 --> 00:03:21.060 picking up and exploring. Anyway so if you live here in the area 00:03:21.060 --> 00:03:29.940 the number is 1-800-KMUD-RAD or 923-3911. Again that 800 number, we do get 00:03:29.940 --> 00:03:33.020 people from all over the States calling so that 800 number, let me just spell 00:03:33.020 --> 00:03:42.940 that out for you, that's 1-800-568-3723. So Dr. Peat I was looking today and I 00:03:42.940 --> 00:03:50.740 guess what's prompted it really is hearing the advice of people touting a 00:03:50.740 --> 00:03:55.900 product called nascent iodine and I know that you specialize in thyroid hormone 00:03:55.900 --> 00:04:03.340 and that iodine is definitely a key component of thyroid hormone and I think 00:04:03.340 --> 00:04:06.620 we've always been led to believe that there has been an adequate supply of 00:04:06.620 --> 00:04:13.340 iodine in the diet and then they produce iodized salt back in the 50s or 60s 00:04:13.340 --> 00:04:18.980 perhaps earlier or not I'm not too sure but iodized salt has been around and 00:04:18.980 --> 00:04:23.340 seafood also contains a lot of iodine in its own right so when I heard about this 00:04:23.340 --> 00:04:31.140 product called nascent iodine they were saying that it was essentially not the 00:04:31.140 --> 00:04:39.140 stable so stable ionic form and was more available was more readily taken up by 00:04:39.140 --> 00:04:43.500 the thyroid gland and then I read some other articles about nascent iodine and 00:04:43.500 --> 00:04:49.400 how reactive it was and I just wanted to feel you out what you what you know 00:04:49.400 --> 00:04:54.180 about the thyroid's natural need for iodine whether or not we are deficient 00:04:54.180 --> 00:04:57.500 and whether or not we need supplementation and if in fact this is 00:04:57.500 --> 00:05:04.700 something actually that may not be necessary. In the 1980s I was looking 00:05:04.700 --> 00:05:11.340 into the iodine nutrition question because I saw some women with breast 00:05:11.340 --> 00:05:19.040 disease who recovered quickly when they took supplements of kelp or thyroid 00:05:19.040 --> 00:05:25.580 hormone and the safest thing I think it is to correct the thyroid 00:05:25.580 --> 00:05:34.380 problem directly rather than counting on big doses of iodine because the large 00:05:34.380 --> 00:05:43.780 doses over many years for example there are about 70 or more publications 00:05:43.780 --> 00:05:50.860 looking at iodine intake around the world over a period of decades and they 00:05:50.860 --> 00:05:58.860 see that over half a milligram or even especially over one milligram of iodine 00:05:58.860 --> 00:06:05.860 per day over a population is closely connected with increased risk of 00:06:05.860 --> 00:06:16.100 thyroiditis and thyroid cancer. Wow, so it's aggravatory. One of the theories of 00:06:16.100 --> 00:06:23.820 why that happens is that iodine spontaneously reacts or in the presence 00:06:23.820 --> 00:06:30.620 of white blood cells their enzymes can cause iodine to react with fatty acids 00:06:30.620 --> 00:06:39.140 that are unsaturated and if you've heard about the iodine number to describe the 00:06:39.140 --> 00:06:49.260 degree of unsaturation of a fat for example the food oils that are highly 00:06:49.260 --> 00:06:56.260 unsaturated have a high iodine number that means the number of molecules of 00:06:56.260 --> 00:07:03.940 iodine that will be spontaneously absorbed by a certain quantity of the 00:07:03.940 --> 00:07:14.060 oil because the iodine attacks the double bonds in the fat and where they 00:07:14.060 --> 00:07:22.020 lack hydrogen saturation the iodine fills in analog saturated hydrogen 00:07:22.020 --> 00:07:29.380 content so there is this tendency of unsaturated fats to react with iodine 00:07:29.380 --> 00:07:36.020 and when that happens the body can interpret that as a signal to the 00:07:36.020 --> 00:07:43.100 thyroid gland possibly imitating the thyroid stimulating hormone. Really? Wow. 00:07:43.100 --> 00:07:47.940 So it doesn't cause an increase of thyroid hormone? 00:07:47.940 --> 00:07:57.140 It can fill the site where thyroid stimulating hormone should be 00:07:57.140 --> 00:08:04.380 acting and it can interfere with that so it probably can go either way forcing 00:08:04.380 --> 00:08:13.340 too much activity or more likely blocking the effect of TSH. The 00:08:13.340 --> 00:08:20.380 polyunsaturated fats by themselves interfere with the enzyme which releases 00:08:20.380 --> 00:08:26.420 thyroid hormone from the gland so too much of the unsaturated fats with or 00:08:26.420 --> 00:08:33.220 without iodine will have an anti thyroid effect but potentially the iodine 00:08:33.220 --> 00:08:42.260 reaction could cause overstimulation by thyroid stimulating hormone or in its 00:08:42.260 --> 00:08:48.340 place could imitate the action. But you mentioned the the binding the iodine 00:08:48.340 --> 00:08:55.180 binding to the double bonds producing this product and in its own right that 00:08:55.180 --> 00:09:02.860 could stimulate a inflammatory thyroiditis and/or a cancer? Yeah I think 00:09:02.860 --> 00:09:09.340 that's why the the high iodine intake around the world statistically is 00:09:09.340 --> 00:09:15.900 associated with greater risk of thyroid cancer and if there really were a 00:09:15.900 --> 00:09:22.220 product that contained a more reactive form of iodine that would just mean that 00:09:22.220 --> 00:09:30.500 it would attack more molecules but I looked up the source of that product of 00:09:30.500 --> 00:09:38.100 one of the products started about 10 years ago and in Texas filed a patent 00:09:38.100 --> 00:09:44.540 that is just completely goofy if you look at the diagram okay it shows 00:09:44.540 --> 00:09:50.300 things that just can't happen right so it was filed 10 years ago and I think 00:09:50.300 --> 00:09:57.020 it still hasn't been and probably never will be actually approved as a patent so 00:09:57.020 --> 00:10:03.260 it you can apply for a patent on any goofy idea and then publish the 00:10:03.260 --> 00:10:08.660 application and impress a lot of people. But maybe not bear the bring the product 00:10:08.660 --> 00:10:16.420 to the market. So iodine supplementation is is very risky and basically you 00:10:16.420 --> 00:10:21.100 should get your trace minerals from seafood sources rather than from 00:10:21.100 --> 00:10:24.980 isolated iodine supplements and especially not in combination with any 00:10:24.980 --> 00:10:30.900 kind of vegetable polyunsaturated oils? Yeah I think that's true. So just to 00:10:30.900 --> 00:10:35.100 quickly wrap up this nascent iodine I think the reason that it caught my 00:10:35.100 --> 00:10:41.060 attention was that the media spin on it was that because it didn't have a and in 00:10:41.060 --> 00:10:43.460 chemistry people hearing this will understand what I'm saying but it's 00:10:43.460 --> 00:10:47.500 probably I can go and elaborate it more simply perhaps but it doesn't have a 00:10:47.500 --> 00:10:52.340 stable octet so it's out of electron shell isn't filled and they were saying 00:10:52.340 --> 00:10:58.500 that because of this it was much more much more suitable in some way to 00:10:58.500 --> 00:11:04.780 occupying these sites in the thyroid to produce thyroid hormone but it's very 00:11:04.780 --> 00:11:09.300 reactivity is counterproductive because surely as soon as you if you could keep 00:11:09.300 --> 00:11:12.500 it as unreactive as that in a bottle waiting to be ingested wouldn't it 00:11:12.500 --> 00:11:15.940 surely and react with one of the first things that came into contact with when 00:11:15.940 --> 00:11:22.500 you ingested it just to fill its octet and become stable again? Oh yeah the whole 00:11:22.500 --> 00:11:29.940 idea of newly born or a nascent molecule when I was in junior high and high 00:11:29.940 --> 00:11:35.980 school the chemistry people talked about nascent oxygen which for a few seconds 00:11:35.980 --> 00:11:40.860 after it's formed in a certain way is highly reactive but that's because the 00:11:40.860 --> 00:11:47.300 electrons are simply in an excited state like it had been sitting in in the 00:11:47.300 --> 00:11:55.140 sunlight too long that's an electronic excitation which quickly passes as it 00:11:55.140 --> 00:12:04.900 gives off a little bit of energy but in in certain short-term situations of a 00:12:04.900 --> 00:12:10.900 few seconds that kind of excited electron state can make a molecule 00:12:10.900 --> 00:12:16.100 useful for certain reactions but isn't something you'd want to put in your body 00:12:16.100 --> 00:12:22.340 yeah okay so not for in vivo use but maybe in in vitro experimentations it 00:12:22.340 --> 00:12:27.660 might have a some kind of a use. So it's basically a more dangerous form of 00:12:27.660 --> 00:12:33.020 iodine that can cause a free radical reaction? Yeah that's what they're 00:12:33.020 --> 00:12:38.500 talking about but I don't think it even exists in the product. Got it okay well 00:12:38.500 --> 00:12:43.460 you're listening to AskUrbDr and Kami DeGalbaville 91.1 FM from 730 00:12:43.460 --> 00:12:47.380 to the end of the show. Callers are invited to call in with any questions 00:12:47.380 --> 00:12:52.540 about this month's wide topic here of things like obviously thyroid hormone is 00:12:52.540 --> 00:12:55.260 going to interplay in a lot of it but the nascent iodine that we've just 00:12:55.260 --> 00:12:59.300 brought up here and then the inflammatory reactions that happen 00:12:59.300 --> 00:13:04.620 between estrogen and nitric oxide and what we can do what females as well as 00:13:04.620 --> 00:13:09.300 males can do to offset their burden. Number here if you live in the area is 00:13:09.300 --> 00:13:13.620 923 3911 if you want an 800 number for toll-free for across the states here 00:13:13.620 --> 00:13:24.180 it's 1-800-568-3723 that translates as 1-800-KMUD-RAD. So Dr. Peat I was 00:13:24.180 --> 00:13:29.500 looking at some abstracts here that we're going to form the show and the 00:13:29.500 --> 00:13:33.660 first couple caught my attention just because they were based on isoflavones 00:13:33.660 --> 00:13:41.340 and I know from our studying herbal medicine soy and isoflavones were all 00:13:41.340 --> 00:13:47.860 the rage and were touted as being very health beneficial reducing cholesterol 00:13:47.860 --> 00:13:52.900 and all this other ridiculously unscientific information that was 00:13:52.900 --> 00:13:58.780 purported. So from the basis of soy they mentioned that there was 00:13:58.780 --> 00:14:08.140 an alcohol soluble fraction that had been shown essentially to basically 00:14:08.140 --> 00:14:15.740 cause female cancers that these things were taken up by the thyroid or they 00:14:15.740 --> 00:14:21.540 probably inhibited the uptake of iodide from in by the thyroid by the gland and 00:14:21.540 --> 00:14:28.700 that this increased the estradiol in females and that this was I know that 00:14:28.700 --> 00:14:33.340 we've heard about soy and now I know we're definitely aware of soy being very 00:14:33.340 --> 00:14:39.300 pro-carcinogenic because it's a estrogen mimic. But what do you what do you think 00:14:39.300 --> 00:14:43.700 about this whole industry push that was producing and probably still is 00:14:43.700 --> 00:14:49.660 producing soy infant formula which is one of the main one of the main foods 00:14:49.660 --> 00:14:57.100 that was generated from it. I think it has seriously harmed lots of kids by 00:14:57.100 --> 00:15:05.740 partly the estrogenic effect. The oil itself has a pro-estrogen effect 00:15:05.740 --> 00:15:14.900 anti-thyroid effect apart from the those little molecules the isoflavones. The 00:15:14.900 --> 00:15:23.820 category of flavones or flavonoids it's very similar to the isoflavones. The 00:15:23.820 --> 00:15:33.100 phenyl group or benzene group is just located slightly closer to the keto 00:15:33.100 --> 00:15:40.460 oxygen in the isoflavones and that group seems to be the estrogenic group. The 00:15:40.460 --> 00:15:46.740 other orientation of the benzene group makes it more likely to be anti 00:15:46.740 --> 00:15:53.660 estrogenic and lots of fruits and vegetables contain the anti-estrogenic 00:15:53.660 --> 00:16:02.980 forms of those but the estrogen industry as a background led to a lot of the 00:16:02.980 --> 00:16:11.980 sales talk about the effects of soy chemicals. And of course is a hugely 00:16:11.980 --> 00:16:19.060 cultivated GMO cultivated product with patents owned for its for its 00:16:19.060 --> 00:16:24.500 propagation and its use. Again no doubt another spawned product from big 00:16:24.500 --> 00:16:30.260 corporations who essentially want to own the product. But don't all legumes have 00:16:30.260 --> 00:16:35.940 these a certain percentage of these isoflavones? Yeah. But just soy is 00:16:35.940 --> 00:16:43.260 particularly high? No I think the main problem with soy besides it being 00:16:43.260 --> 00:16:52.780 basically inedible I think the main problem is that it's almost all grown in 00:16:52.780 --> 00:16:59.580 the genetically modified form that takes large amounts of toxic pesticides. Which 00:16:59.580 --> 00:17:04.860 are estrogenic too right? Yeah. And again just for the guys out there I think it's 00:17:04.860 --> 00:17:09.660 very important to make you aware that you know guys have estrogen. It's not 00:17:09.660 --> 00:17:16.620 just a female dominated situation and soy consumption in males has also been 00:17:16.620 --> 00:17:21.980 positively associated with things like gynecomastia which is another side 00:17:21.980 --> 00:17:26.980 effect if you like of estrogen activity within males. The very same thing Dr. B 00:17:26.980 --> 00:17:32.020 also isn't it with alcohol drinking alcohol excess excessively can produce 00:17:32.020 --> 00:17:38.420 a symptom of male breasts so that's a estrogen type reaction. When I was a kid 00:17:38.420 --> 00:17:47.940 just before the Second World War we knew some of the very poor immigrants to 00:17:47.940 --> 00:17:54.620 California and there was one couple in which the wife got a job but the father 00:17:54.620 --> 00:17:59.580 could nurse the baby because his estrogen had become so high for 00:17:59.580 --> 00:18:05.580 malnutrition and at the end of the Second World War when soldiers got out 00:18:05.580 --> 00:18:11.040 of the prison camps lots of them had breasts from the effects of prolonged 00:18:11.040 --> 00:18:17.980 starvation. Are we talking lactation too? Well in the case of this man in 00:18:17.980 --> 00:18:27.460 California the wife said pause milk ain't got much strength. Yeah they can 00:18:27.460 --> 00:18:33.940 lactate if they have a baby nursing. Wow so there's enough positive 00:18:33.940 --> 00:18:39.100 feedback in the physiological mechanism there inherently to to produce that. So I 00:18:39.100 --> 00:18:43.780 guess the high estrogen then stimulated raised their prolactin? Yeah. And then 00:18:43.780 --> 00:18:47.820 with the suckling it produced milk? Yeah. That is just absolutely 00:18:47.820 --> 00:18:53.420 incredible. Okay so again just for people that are listening it just begs the 00:18:53.420 --> 00:19:00.060 question again where things like soy and soy products all we ever hear we don't 00:19:00.060 --> 00:19:03.380 have a television really or listen we don't have a TV at all but we don't 00:19:03.380 --> 00:19:07.580 listen to either you know broadcasts from mainstream media but what I was 00:19:07.580 --> 00:19:10.660 going to say was most people have a TV or they're listening to a regular radio 00:19:10.660 --> 00:19:15.260 station getting the same spin put on things and the same sales pitch and so 00:19:15.260 --> 00:19:20.100 I'm just find it hard to believe that for a long time the whole soy thing 00:19:20.100 --> 00:19:24.100 could exist and it could do what it did when actually it's more like a waste 00:19:24.100 --> 00:19:28.340 product and people really shouldn't be eating soy because it's so dangerous in 00:19:28.340 --> 00:19:32.860 terms of its estrogenic effect on females and males and those estrogenic 00:19:32.860 --> 00:19:36.100 effects are very pro-inflammatory. Dr. Peat you've pointed out many many 00:19:36.100 --> 00:19:42.260 occasions and I'm currently on board with that same feeling that the the 00:19:42.260 --> 00:19:45.500 irritation and the inflammation that estrogen promotes is nothing but a 00:19:45.500 --> 00:19:51.580 dangerous process in the body. And also Dr. Peat how would you compare 00:19:51.580 --> 00:19:59.620 estrogen levels with menopausal women and men? With the aging a man's 00:19:59.620 --> 00:20:06.780 estrogen pretty steadily increases but if he has a heart attack it goes up 00:20:06.780 --> 00:20:15.460 sharply or if he has a traumatic injury it goes up during the recovery time but 00:20:15.460 --> 00:20:25.180 generally there's a trend upward in men and in women when the ovaries stop 00:20:25.180 --> 00:20:34.220 cycling there up until about the age of 38 to 40 there is a an actual steady 00:20:34.220 --> 00:20:42.700 increase in estrogen and when the ovaries stop cycling they stop suddenly 00:20:42.700 --> 00:20:49.220 producing progesterone but they continue producing a considerable 00:20:49.220 --> 00:20:55.820 amount of estrogen until the body can adjust it downward. So there are a 00:20:55.820 --> 00:21:03.060 few years in the 40s or early 50s usually when estrogen is extremely 00:21:03.060 --> 00:21:11.380 excessive relative to the anti-estrogen effect of progesterone but then again 00:21:11.380 --> 00:21:17.860 after the ovaries have pretty much stopped functioning with the rest of 00:21:17.860 --> 00:21:28.340 the body as the progesterone fails all of the other tissues begin the same way 00:21:28.340 --> 00:21:35.820 that happens in men. All of a woman's tissues tend to start increasing their 00:21:35.820 --> 00:21:42.260 production of estrogen so that after menopause the fatter a woman is the more 00:21:42.260 --> 00:21:48.540 estrogen she's producing because the fat tissue is a good source of it but on any 00:21:48.540 --> 00:21:55.740 tissue after menopause to the degree that it's stressed will begin producing 00:21:55.740 --> 00:22:02.140 estrogen. So is it about the same level between men and women? Yeah. After the 00:22:02.140 --> 00:22:09.500 menopausal period? I think women tend to be fatter in old age and so they are 00:22:09.500 --> 00:22:14.860 more likely to have a higher level of estrogen but just measuring the blood 00:22:14.860 --> 00:22:24.460 estrogen gives a misleading impression because when progesterone is 00:22:24.460 --> 00:22:31.940 deficient the estrogen receptor as well as the aromatase enzyme that makes 00:22:31.940 --> 00:22:38.220 estrogen the receptors bind it in cells and there's no progesterone to destroy 00:22:38.220 --> 00:22:45.900 the estrogen receptor so it just stays in the cell and some of the enzymes that 00:22:45.900 --> 00:22:53.500 are no longer inactivated by progesterone other enzymes capture 00:22:53.500 --> 00:23:00.140 circulating estrogen that should have been excreted cause it to be deposited 00:23:00.140 --> 00:23:09.460 in cells. Still other enzymes shift any estrogen away from the estrone form to 00:23:09.460 --> 00:23:16.700 the estriol form which is the most active intense estrogen. So everything 00:23:16.700 --> 00:23:25.140 that happens when progesterone is deficient tends to load up various cells 00:23:25.140 --> 00:23:31.500 all through the body with more and more estrogenic stimulation even though it 00:23:31.500 --> 00:23:36.380 isn't being released to be measured in the blood. Right so the blood test could 00:23:36.380 --> 00:23:41.260 appear that it's fine but if you have a large amount of fat cells that could be 00:23:41.260 --> 00:23:45.460 stored in that and other tissues and what about weight loss for women who are 00:23:45.460 --> 00:23:49.740 in the menopause if they lose that weight do they then poison themselves 00:23:49.740 --> 00:23:55.020 with estrogen as it comes out of the cells? Just temporarily but it's better 00:23:55.020 --> 00:24:01.900 to get rid of it and have it local because inside the cells it produces 00:24:01.900 --> 00:24:10.500 things such as breast cancer lung cancer uterine cancer ovarian cancer all of the 00:24:10.500 --> 00:24:17.020 tissues that no longer have enough progesterone are subject to cancer. So 00:24:17.020 --> 00:24:21.540 what about the women that continue to menstruate like I heard from this lady 00:24:21.540 --> 00:24:29.780 the other day that she had a friend who was 17 was still menstruating. I talked 00:24:29.780 --> 00:24:35.300 to a gynecologist who was giving his wife progesterone and she was still 00:24:35.300 --> 00:24:46.300 menstruating at 60 and if you happen to have a very good system for producing 00:24:46.300 --> 00:24:52.300 progesterone there's no reason why it shouldn't stop at 55. There's no reason 00:24:52.300 --> 00:24:57.540 to stop at 55 then right? No. I mean basically would do you think it would be 00:24:57.540 --> 00:25:00.620 beneficial that women continue to menstruate until the day they die? I 00:25:00.620 --> 00:25:12.820 think so. Like the flamingos? Yeah flamingos have no life limitation 00:25:12.820 --> 00:25:21.820 according to ordinary mortality curves. They seemed only died by accident. 00:25:21.820 --> 00:25:28.020 Starvation right? Okay you're listening to Ask Your Doctor KMUD Galbraithville 91.1 FM 00:25:28.020 --> 00:25:31.940 from 7.30 till the end of the show. Please call in with any questions you 00:25:31.940 --> 00:25:35.500 have either related or unrelated to this month's subject. Number if you're in the 00:25:35.500 --> 00:25:42.060 area area code 707 923 3911 or for those folks in different states across the US 00:25:42.060 --> 00:25:49.140 has an 800 number which is 1-800-568-3723. Dr. Peat I wanted to pick up on a 00:25:49.140 --> 00:25:52.220 point that you mentioned during your last discourse then I did I've not had 00:25:52.220 --> 00:25:56.700 that before. Progesterone destroys the estrogen receptor. Does anything 00:25:56.700 --> 00:26:00.300 similarly happen with estrogen doing the same thing to progesterone receptors or 00:26:00.300 --> 00:26:06.060 is it just that way around? Well estrogen activates its own receptor in most 00:26:06.060 --> 00:26:16.060 tissues and it will activate inflammatory things which tend to turn 00:26:16.060 --> 00:26:22.100 off the progesterone receptor if you have an excess. 00:26:22.100 --> 00:26:33.300 Generally the normal function would be for progesterone to rise as soon as the 00:26:33.300 --> 00:26:40.300 estrogen has had its surge and then knock it out. The estrogen is fine if 00:26:40.300 --> 00:26:46.820 it's active only for 12 to 24 hours every month. Right, right. It does its job and 00:26:46.820 --> 00:26:51.020 then it's finished. But like you said the tissues will carry on producing estrogen 00:26:51.020 --> 00:26:57.260 especially in obese individuals and menopause or even postmenopausal 00:26:57.260 --> 00:27:03.620 women. Yeah Alexander Lipschutz showed that if you remove the ovaries and then 00:27:03.620 --> 00:27:11.860 implant just a tiny estrogen releasing pellet just a very small but continuous 00:27:11.860 --> 00:27:19.620 dose it's very carcinogenic. But if you interrupt that or even a large dose with 00:27:19.620 --> 00:27:26.100 estrogen with progesterone periodically you don't get cancer. And in his 00:27:26.100 --> 00:27:34.660 experiments the estrogen uninterrupted was carcinogenic to uterus, breast, lungs, 00:27:34.660 --> 00:27:41.700 kidneys, brain and intestine. Yeah. Basically everything. Okay so just 00:27:41.700 --> 00:27:46.700 another another call for all the ladies out there. There really is nothing I 00:27:46.700 --> 00:27:50.180 know it's a personal thing but there's nothing wrong with continuing your 00:27:50.180 --> 00:27:54.020 menstrual cycle as long as you possibly can. Progesterone is your friend, 00:27:54.020 --> 00:27:58.140 estrogen is your enemy and the only thing really that estrogen is any good 00:27:58.140 --> 00:28:02.380 for is the implantation. So I may have a first caller so let's get this first 00:28:02.380 --> 00:28:09.420 caller on the air. Caller where are you from? I'm from Kansas City. Did you say Kansas City? 00:28:09.420 --> 00:28:18.020 Yeah Kansas City. Oh hey welcome to the show. Thanks. Hi Dr. Peat. What do you think is 00:28:18.020 --> 00:28:22.580 happening if someone experiences digested cramps and bloating within 30 minutes 00:28:22.580 --> 00:28:27.180 when using vitamin E orally and which still occurs even when switching to a 00:28:27.180 --> 00:28:31.780 few different products as well as even when using several drops of progeste 00:28:31.780 --> 00:28:41.660 which also contains vitamin E? I think it's the viscous oily quality that is 00:28:41.660 --> 00:28:50.860 irritating. Some people have that reaction for example if they try to 00:28:50.860 --> 00:28:57.300 use it in their armpit where the skin is very sensitive the highly viscous oil 00:28:57.300 --> 00:29:04.620 can be very irritating so I think it should be taken with food so that it 00:29:04.620 --> 00:29:10.500 doesn't hit any of the membranes in the concentrated form. Do you think it's 00:29:10.500 --> 00:29:22.020 possible to develop a soy allergy somewhere along the way? Yeah many people 00:29:22.020 --> 00:29:30.340 do have soy allergies but the oil doesn't contain any of the proteins that 00:29:30.340 --> 00:29:40.100 people are allergic to so I haven't heard of any documented allergy to oily 00:29:40.100 --> 00:29:48.060 soy products such as soy oil. Okay do you think it's possible that for that person 00:29:48.060 --> 00:29:52.020 that's something like 400 units international units of the 00:29:52.020 --> 00:29:57.220 alpha-tocopherol with 300 milligrams of gamma, delta and beta-tocopherol is 00:29:57.220 --> 00:30:02.220 excessive and possibly being excreted mostly in bile which is alkaline and 00:30:02.220 --> 00:30:06.220 possibly irritating to an already irritated intestine which would maybe 00:30:06.220 --> 00:30:17.580 cause the cramps and bloating? I doubt it because the effect of vitamin E on many 00:30:17.580 --> 00:30:24.740 cell processes is anti-inflammatory for example it inhibits prostaglandin 00:30:24.740 --> 00:30:35.620 formation similar to aspirin in its range of anti-inflammatory effects. 00:30:36.620 --> 00:30:40.780 Okay that's great thank you. All right thank you for your call. We do have another call 00:30:40.780 --> 00:30:44.180 on the air so let's take this next caller. Caller where are you from? 00:30:44.180 --> 00:30:49.580 Hi I'm calling from Mexico. Mexico, the first caller from Mexico. Welcome to the 00:30:49.580 --> 00:30:56.460 show what's your question? Thanks hi if I understood correctly earlier you were 00:30:56.460 --> 00:31:04.020 talking about how taking extra iodine can interact with PUFA to cause problems 00:31:04.020 --> 00:31:12.460 and I know someone who took a few milligrams of extra iodine and she went 00:31:12.460 --> 00:31:21.100 into a some kind of thyroid hyperthyroid like crisis state where she couldn't 00:31:21.100 --> 00:31:27.420 tolerate any physical exertion. Her muscles were really weak and her pulse 00:31:27.420 --> 00:31:35.540 was very high and years later she still gets that reaction from thyroid and I 00:31:35.540 --> 00:31:44.860 was wondering if that's related to iodine? Back in the years when many people 00:31:44.860 --> 00:31:56.180 were in certain regions for example in southern Mexico, western China and Ohio 00:31:56.180 --> 00:32:03.860 Eastern Europe those areas were very deficient in iodine and they would 00:32:03.860 --> 00:32:10.500 develop an enlargement of the thyroid gland and then when they ate iodine even 00:32:10.500 --> 00:32:17.700 a fairly normal amount suddenly their gland would start forming thyroid hormone 00:32:17.700 --> 00:32:27.300 and if the goiter was very big they could have serious hyperthyroidism that 00:32:27.300 --> 00:32:33.700 could last for years but if the gland was just slightly swollen it would pass 00:32:33.700 --> 00:32:42.060 in about two months. So that's a that's a very real sequelae of using iodine in 00:32:42.060 --> 00:32:48.140 that particular individual that they would have that increased thyroid 00:32:48.140 --> 00:32:51.700 production that would be you know resulting in what the callers just 00:32:51.700 --> 00:32:57.380 mentioned? Yeah if they took their iodine in the form of thyroid hormone they could 00:32:57.380 --> 00:33:05.340 normalize their body functions and be replacing iodine in a limited 00:33:05.340 --> 00:33:09.820 graded fashion so that they wouldn't go into those hyperthyroid states and 00:33:09.820 --> 00:33:16.340 getting the required amount of hormone would cause their pituitary to settle 00:33:16.340 --> 00:33:22.300 down and let the gland gradually shrink. Because that is treatment for goiter is 00:33:22.300 --> 00:33:28.300 that you supplement with thyroid hormone? Yes to treat hyperthyroidism 00:33:28.300 --> 00:33:34.860 the safest thing is to supplement usually with thyroid hormone. So again 00:33:34.860 --> 00:33:39.120 just to just to expand on the very first question to Dr. Peat about the nascent 00:33:39.120 --> 00:33:44.140 iodine it's not a good idea and also many other forms of iodine 00:33:44.140 --> 00:33:48.660 supplementation is not necessary and if you need iodine and you have any kind of 00:33:48.660 --> 00:33:52.900 low thyroid actually thyroid hormone is the best way to get bound iodine. Okay 00:33:52.900 --> 00:33:58.340 did you have anything else you wanted to bring out caller? Well thanks a lot I was 00:33:58.340 --> 00:34:03.540 just wondering if it you know if it would be a good idea to do anything 00:34:03.540 --> 00:34:10.740 specific to try to rectify this this problem or if there's any tips on 00:34:10.740 --> 00:34:17.620 tolerating thyroid does avoiding iodine help in a situation like that? The people 00:34:17.620 --> 00:34:25.500 who have trouble with the actual thyroid hormone they can be either deficient in 00:34:25.500 --> 00:34:32.540 magnesium because hypothyroidism makes all of your tissues fail to retain a 00:34:32.540 --> 00:34:38.020 normal amount of magnesium and then when you supplement it suddenly you 00:34:38.020 --> 00:34:44.300 experience an extreme magnesium deficiency in your heart for example and 00:34:44.300 --> 00:34:51.940 your brain and so taking some magnesium at the same time as the thyroid it will 00:34:51.940 --> 00:34:59.380 help those people. Others if they're deficient in adrenal or ovarian or 00:34:59.380 --> 00:35:08.220 gonadal steroids will suffer stress symptoms when they take thyroid and and 00:35:08.220 --> 00:35:14.860 so using a supplement such as pregnenolone will make them tolerate 00:35:14.860 --> 00:35:20.060 adapting to the thyroid more easily. And what about Dr. Peat how some people if 00:35:20.060 --> 00:35:25.220 they supplement with t4 thyroxine they will have those symptoms like our caller 00:35:25.220 --> 00:35:29.260 mentioned where their muscles are weak and they their hearts pounding they're 00:35:29.260 --> 00:35:33.460 pulses high and isn't that because if they're already low thyroid and they 00:35:33.460 --> 00:35:36.580 take the t4 then they're actually stimulating the adrenaline because 00:35:36.580 --> 00:35:42.300 they're not converting it? Yeah when when people have suffered for a long time 00:35:42.300 --> 00:35:48.940 with low thyroid they're likely to have extremely high adrenaline and cortisol 00:35:48.940 --> 00:35:57.780 levels and that causes them to turn t4 into reverse t3 blocking the actual 00:35:57.780 --> 00:36:05.700 active t3 hormone and then if they accumulate more and more t4 that will 00:36:05.700 --> 00:36:13.220 interfere competitively with a little bit of t3 that they do have so they can 00:36:13.220 --> 00:36:20.380 exaggerate the state of their hypothyroidism if they're in that really 00:36:20.380 --> 00:36:26.460 extreme stress state. Could you say that t4 perhaps is mainly only 10% as 00:36:26.460 --> 00:36:35.340 active as the active t3 hormone? It really varies in the 1940s when they 00:36:35.340 --> 00:36:43.060 first synthesized it they tested it on male medical students and it was exactly 00:36:43.060 --> 00:36:53.300 as effective as armor natural thyroid but that's because young men 20 22 years 00:36:53.300 --> 00:37:02.060 old have very good livers that can perfectly convert it but even at the 00:37:02.060 --> 00:37:08.860 same age women are more likely to have problems with plain thyroxine. But when 00:37:08.860 --> 00:37:14.500 they talk about t4 being weakly active how do you how do you interpret that or 00:37:14.500 --> 00:37:21.260 how do you see t3 versus t4 in terms of orchestrating metabolic events? 00:37:21.260 --> 00:37:30.140 The standard textbook idea is that t3 is four times more powerful than t4 00:37:30.140 --> 00:37:36.220 but really if your liver is good you can get a hundred percent of the benefit out 00:37:36.220 --> 00:37:46.900 of t4 and if you're a woman under stress with high estrogen your liver isn't 00:37:46.900 --> 00:37:53.780 going to convert any of it to the right active hormone and the more you take I've 00:37:53.780 --> 00:38:01.740 known of one woman was hospitalized and got more and more hypothyroid the higher 00:38:01.740 --> 00:38:06.740 they raised her thyroxine dose and as soon as they gave her t3 became right 00:38:06.740 --> 00:38:13.420 out of the myxedema coma but I've seen people in less extreme states who got 00:38:13.420 --> 00:38:18.500 more and more depressed or psychotic or whatever when they increased their 00:38:18.500 --> 00:38:22.780 thyroxine dose. Okay I have one more question for the caller do you know if 00:38:22.780 --> 00:38:28.140 this lady you're speaking about was taking a t3 t4 combination supplement or 00:38:28.140 --> 00:38:33.060 were they taking just t4 or just t3 are you aware of that? Well yeah originally 00:38:33.060 --> 00:38:38.540 she was taking an armor supplement and when she took the supplemental iodine 00:38:38.540 --> 00:38:45.340 that caused the problem and since then she has tried different t4 t3 combo 00:38:45.340 --> 00:38:52.020 products as well as a couple different pure t3 supplements so I think it's 00:38:52.020 --> 00:38:56.860 something to do with this adrenaline or sensitivity to adrenaline that Dr. 00:38:56.860 --> 00:39:02.700 Peat was was talking about where if I understand it correctly the thyroid 00:39:02.700 --> 00:39:09.900 sensitizes the tissues to the already high the already existing adrenaline. But 00:39:09.900 --> 00:39:13.340 that should only last a couple days and then it should balance out. Well 00:39:13.340 --> 00:39:20.860 sometimes it lasts for a couple of weeks if you're really extreme you have to use 00:39:20.860 --> 00:39:28.860 little bits of supplements and be very careful about your intake of protein 00:39:28.860 --> 00:39:37.360 sugar calcium everything that is counter to the stress. So when you're in a 00:39:37.360 --> 00:39:42.660 situation like that she was using very small specks of t3 you know under one 00:39:42.660 --> 00:39:48.260 microgram sometimes is this thing to do to hold that very low dose for a couple 00:39:48.260 --> 00:39:52.820 weeks and then increase it in very very small increments as the adrenaline 00:39:52.820 --> 00:40:02.060 hopefully comes down? Yeah I've known people who for a week or two would stay 00:40:02.060 --> 00:40:10.420 with one microgram doses of t3 but you have to make sure your whole diet 00:40:10.420 --> 00:40:20.460 is very good. Having hormone tests and a vitamin D blood test is helpful because 00:40:20.460 --> 00:40:27.500 magnesium and calcium work together and vitamin D regulates them. Yeah and making 00:40:27.500 --> 00:40:31.100 sure that she's getting plenty of carbohydrates like in the form of fruit 00:40:31.100 --> 00:40:35.980 juices because that's like Dr. Peat saying make sure nutritionally she's 00:40:35.980 --> 00:40:40.180 getting at least 75 grams of protein. I don't know the weight and nutritional 00:40:40.180 --> 00:40:48.740 needs but at least 150 grams or more of sugars and good fats. Okay thanks very 00:40:48.740 --> 00:40:53.260 much. All right thanks for sure. I think we have another caller there. Yeah okay we 00:40:53.260 --> 00:40:57.660 have the next caller. Caller where are you from? Hi I'm calling from New York. Yeah 00:40:57.660 --> 00:41:02.700 welcome to the show. What's your question? Hi I have a question for Dr. Peat about 00:41:02.700 --> 00:41:09.380 Buteyko breathing and heart rate. Dr. Buteyko noted that as you progress with 00:41:09.380 --> 00:41:15.180 retaining more and more co2 with the Buteyko breathing then the heart rate 00:41:15.180 --> 00:41:20.780 will decrease and I wondered what you thought about that. I've noticed that in 00:41:20.780 --> 00:41:26.780 my own practice that it does go down but the temperature is still good and I 00:41:26.780 --> 00:41:34.260 wondered if the metabolism is still good when that happens or what you think 00:41:34.260 --> 00:41:39.740 about it? Yeah there have been experiments with animals increasing 00:41:39.740 --> 00:41:47.020 their co2 and watching what happens to the heart and blood vessels and co2 00:41:47.020 --> 00:41:54.020 relaxes the blood vessels so it decreases peripheral resistance and that 00:41:54.020 --> 00:42:02.500 makes the heart able to pump more blood more easily with less work. So it usually 00:42:02.500 --> 00:42:11.100 means a bigger stroke volume. Okay so the decreased heart rate. Even though it's a 00:42:11.100 --> 00:42:18.620 lower heart rate you think that that you can still get the same benefits as you 00:42:18.620 --> 00:42:23.180 would if you weren't restricting your breathing but I mean I mean I know you 00:42:23.180 --> 00:42:27.260 recommend a high heart rate typically for people that aren't practicing that 00:42:27.260 --> 00:42:35.020 kind of breath control. Yeah but that's most people are running on 00:42:35.020 --> 00:42:42.180 adrenaline. I've known people who one woman had had a hundred and eighty pulse 00:42:42.180 --> 00:42:48.700 steadily for years another person had been around 130 resting pulse for a long 00:42:48.700 --> 00:42:54.860 time. Both of these people within two weeks got down to a normal under a 00:42:54.860 --> 00:43:00.380 hundred pulse rate when they supplemented thyroid and one of the 00:43:00.380 --> 00:43:06.500 things the thyroid is doing is increasing your co2 decreasing the 00:43:06.500 --> 00:43:13.380 lactic acid and the inflammation so that your capillaries open up you have less 00:43:13.380 --> 00:43:21.180 peripheral resistance so your heart doesn't have to work so frantically. Okay 00:43:21.180 --> 00:43:25.980 well thank you very much. Thanks dear call caller. Okay so for anybody else 00:43:25.980 --> 00:43:29.380 listening here it's always good to get people from all over the state so we've 00:43:29.380 --> 00:43:33.180 had Mexico so far we've had New York Midwest so let's keep it up there's an 00:43:33.180 --> 00:43:40.460 800 number here it's 800 568 3723 we've got Dr. Ray Peat with us on the show and 00:43:40.460 --> 00:43:43.980 he's sharing his wisdom so I guess until the phones ring again for the next time 00:43:43.980 --> 00:43:47.820 I wanted to ask you we haven't actually got very far through with all the 00:43:47.820 --> 00:43:50.620 questions I wanted to ask you at this point which is good news because people 00:43:50.620 --> 00:43:54.220 have been calling but I may have to carry on this topic next month perhaps if 00:43:54.220 --> 00:43:58.060 you're available. I saw the article there which again just highlights the 00:43:58.060 --> 00:44:02.420 estrogenic problem that the benign and malignant thyroid nodules are far more 00:44:02.420 --> 00:44:08.100 common in females than males no doubt a consequence of estradiol so given that 00:44:08.100 --> 00:44:14.060 the mainstream lie is that estrogen is good for you and healthy and what can be 00:44:14.060 --> 00:44:17.700 done do you think simply to offset the estrogen I know you've mentioned 00:44:17.700 --> 00:44:22.180 progesterone which is probably the first thing that springs into my mind but in 00:44:22.180 --> 00:44:30.860 terms of reducing a female's estrogenic burden. There were some studies of slices 00:44:30.860 --> 00:44:39.840 of thyroid gland in vitro and they found that added estrogen caused the cells to 00:44:39.840 --> 00:44:47.340 keep synthesizing hormone but and to keep growing but to fail to secrete any 00:44:47.340 --> 00:44:53.660 of the hormone when they added progesterone it began secreting the 00:44:53.660 --> 00:45:03.360 hormone and up until the last few decades women rather than just having 00:45:03.360 --> 00:45:09.480 nodules in their thyroid they were the ones most susceptible to growing a 00:45:09.480 --> 00:45:19.080 very large goiter that sometimes was as big as a cantaloupe and the nodules are 00:45:19.080 --> 00:45:28.760 basically the same process of estrogen activating the cell division and 00:45:28.760 --> 00:45:38.920 synthesis of colloid the material that the hormone later will be made from and 00:45:38.920 --> 00:45:47.680 desensitizing the cells to the the hormone secreting effect of thyroid 00:45:47.680 --> 00:45:56.560 stimulating hormone and progesterone by antagonizing estrogen will reverse those 00:45:56.560 --> 00:46:05.200 processes but when you get the cells multiplying and making the protein you 00:46:05.200 --> 00:46:14.200 will get at least a nodule maybe if it continues steadily the whole gland will 00:46:14.200 --> 00:46:18.120 get bigger and bigger. Okay we do actually have another caller so let's 00:46:18.120 --> 00:46:21.560 just hold that for right there and take this next caller so caller you're on the 00:46:21.560 --> 00:46:26.720 air and where you from? How you doing I'm from right here in town. Okay a local 00:46:26.720 --> 00:46:32.160 caller you're welcome what's your question? I was curious to know if this I 00:46:32.160 --> 00:46:39.160 heard you talking about the vitamin D in the thyroid and the magnesium I'm just 00:46:39.160 --> 00:46:41.960 wondering if that would have anything to do with what's called restless legs 00:46:41.960 --> 00:46:47.040 syndrome. Yeah Dr. Peat that magnesium deficiency or how would you explain 00:46:47.040 --> 00:46:55.400 restless legs syndrome? There has been quite a lot of research for example they 00:46:55.400 --> 00:47:02.440 noticed that people taking SSRI antidepressants tended to have episodes 00:47:02.440 --> 00:47:10.360 of restless legs and so they saw that nitric oxide and serotonin were 00:47:10.360 --> 00:47:18.240 involved in producing it and those are produced largely from the intestine the 00:47:18.240 --> 00:47:24.760 most intense problem of both serotonin and nitric oxide production is from an 00:47:24.760 --> 00:47:33.680 irritated intestine and hypothyroid people over produce both nitric oxide 00:47:33.680 --> 00:47:41.560 and serotonin typically and have sluggish digestive systems and often 00:47:41.560 --> 00:47:50.720 have a tendency to generalized inflammation and the serotonin seems to 00:47:50.720 --> 00:47:58.520 be specifically what pushes those motor nerves the cause of the leg jumpiness. 00:47:58.520 --> 00:48:04.040 Does that help you out or explain things to you caller? Yeah yeah somewhat it does 00:48:04.040 --> 00:48:10.400 it's not an adrenaline thing that makes the legs jump it's serotonin yeah 00:48:10.400 --> 00:48:16.360 having to do with what sorry all of the inflammatory stress things tend to go 00:48:16.360 --> 00:48:21.400 together. So would you recommend like aspirin for restless leg syndrome? Um 00:48:21.400 --> 00:48:30.360 yeah pregnenolone aspirin and avoiding irritating foods especially legumes and 00:48:30.360 --> 00:48:37.040 raw green salads those are very irritating. Those are things that increase 00:48:37.040 --> 00:48:46.200 the bowel production of serotonin? Yeah. Beans and raw vegetables? That's 00:48:46.200 --> 00:48:49.800 interesting because we just switched to trying to eat better and we had gone to 00:48:49.800 --> 00:48:54.720 eating a lot more both of those. Have you noticed your restless leg syndrome? 00:48:54.720 --> 00:49:02.400 It's a female it's my partner. Okay. And it's becoming very extreme and that 00:49:02.400 --> 00:49:08.920 may very well be just from the diet. She was has a vitamin D 00:49:08.920 --> 00:49:16.400 deficiency. She's told to take vitamin D and magnesium. Yeah. Do you know what 00:49:16.400 --> 00:49:20.880 her vitamin D level was and how much she's taking? I don't know exactly 00:49:20.880 --> 00:49:26.560 in measurement but it was very low. Right. Well the most most drop forms of 00:49:26.560 --> 00:49:31.640 vitamin D now that 2,000 IU a drop and if she has low vitamin D it's probably 00:49:31.640 --> 00:49:36.800 below 20 maybe right around 20 which is very low and they've raised the 00:49:36.800 --> 00:49:42.960 reference limit for vitamin D now up to about 45 so you supplementing with a 00:49:42.960 --> 00:49:48.880 2,000 IU per day drop product she should be really loading up with six to 00:49:48.880 --> 00:49:54.360 eight drops a day for about four or five days and then getting 4,000 to 6,000 IU 00:49:54.360 --> 00:50:00.360 and then re-measuring her vitamin D. After about two months. Yeah. Okay so 00:50:00.360 --> 00:50:05.320 Dr. Peat said that bowel irritation, inflammation will increase serotonin 00:50:05.320 --> 00:50:08.440 production and that serotonin production with nitric oxide which we're going to 00:50:08.440 --> 00:50:12.400 got a question for Dr. Peat about nitric oxide both those two compounds there can 00:50:12.400 --> 00:50:17.900 be predisposed predisposing someone to restless leg syndrome. Anyway 00:50:17.900 --> 00:50:23.120 thanks for your call. So Dr. Peat I saw today just in fact I was thinking about 00:50:23.120 --> 00:50:26.880 it myself. I started looking at a couple of websites that do blood 00:50:26.880 --> 00:50:30.640 testing etc and I couldn't see any nitric oxide blood testing tests done 00:50:30.640 --> 00:50:38.160 but I did see salivary tests for those salivary nitrite strips to assess the 00:50:38.160 --> 00:50:43.520 potential nitric oxide production in the body. I know it will be formed from 00:50:43.520 --> 00:50:49.320 nitrite or nitrate and this site actually was this the funny thing is 00:50:49.320 --> 00:50:53.480 this site was actually letting you know how you could increase your nitric oxide 00:50:53.480 --> 00:50:56.840 more now you've been eating various foods which I wanted to question about 00:50:56.840 --> 00:51:00.060 also because I know some of the Greens here that were promoting the nitric 00:51:00.060 --> 00:51:04.080 oxide production with things that we actually are promoting as being 00:51:04.080 --> 00:51:08.120 beneficial but there's obviously a reason for that now. So how do you feel 00:51:08.120 --> 00:51:13.600 about testing your salivary nitrate nitrite level and how predictive or 00:51:13.600 --> 00:51:18.600 preemptive that would be of nitric oxide production systemically? A recent 00:51:18.600 --> 00:51:24.080 article just a couple of weeks ago came out suggesting measuring the nitric 00:51:24.080 --> 00:51:29.560 oxide or its products in the body as a way of diagnosing hypothyroidism because 00:51:29.560 --> 00:51:35.560 they're so closely connected but I would guess that the urine might be better 00:51:35.560 --> 00:51:41.640 than the saliva because for other hormone testing for example just 00:51:41.640 --> 00:51:46.680 thinking of food or being anxious or whatever can really change the 00:51:46.680 --> 00:51:51.020 composition of your saliva. Right okay so you think that because that changes so 00:51:51.020 --> 00:51:55.040 quickly then you're saying it's a not probably more relative to test something 00:51:55.040 --> 00:51:59.720 that's there and it's stored and probably more representative of a 00:51:59.720 --> 00:52:06.840 couple of hours of physiology? Yeah I think that the urine will give you a 00:52:06.840 --> 00:52:12.120 good picture of your level of stress. You wouldn't want to test that after eating 00:52:12.120 --> 00:52:15.040 spinach either with your saliva. Here's the other thing that was my other 00:52:15.040 --> 00:52:19.560 question is even this website was touting nitric oxide as being beneficial 00:52:19.560 --> 00:52:23.560 and actually spinach was a very good producer of nitrite and how that 00:52:23.560 --> 00:52:27.400 was spinach would increase your nitric oxide and and they were touting 00:52:27.400 --> 00:52:32.600 that. I know and I just want to ask you just to be realistic here and be real 00:52:32.600 --> 00:52:38.320 for folks I know we mentioned greens purporting greens and boiled greens and 00:52:38.320 --> 00:52:43.000 drinking the juice is very beneficial I know that you do say that kale can have 00:52:43.000 --> 00:52:47.360 a thyroid suppressive effect so not to use much kale but spinach I think has 00:52:47.360 --> 00:52:52.400 been one of those greens that has been portrayed as being relatively healthy so 00:52:52.400 --> 00:52:56.480 what do you what do you think about spinach? If they're organically grown 00:52:56.480 --> 00:53:03.280 without intense nitrate fertilization and if it's well cooked I think 00:53:03.280 --> 00:53:07.120 spinach is good food. Okay we do have two more callers I don't know if we're 00:53:07.120 --> 00:53:11.000 going to get them in they just appeared on the dial so let's say this next 00:53:11.000 --> 00:53:14.720 caller. Caller where are you from? Hello? Yeah you're on the air where are you from? 00:53:14.720 --> 00:53:18.920 Yeah I'm from Shelter Cove. Shelter Cove hi what's your question? My question 00:53:18.920 --> 00:53:25.920 is for my daughter actually she wants to take testosterone and I'm wondering what 00:53:25.920 --> 00:53:30.240 his take on it is if he has any experience with that how she can keep 00:53:30.240 --> 00:53:34.160 herself healthy. How old is she and what's the what's the indication for 00:53:34.160 --> 00:53:39.280 taking the testosterone? Well she's transgender she wants to be more male 00:53:39.280 --> 00:53:48.000 and she is 16. 16 okay and I did you catch what the symptom was? She's 00:53:48.000 --> 00:53:53.000 transgender. Okay transgender I didn't really hear that properly. Dr. Peat? 00:53:53.000 --> 00:54:01.000 Wanting to masculinize? Yes. I think that's safe but it should be backed up 00:54:01.000 --> 00:54:08.680 with pregnenolone and some progesterone to keep things in balance because the 00:54:08.680 --> 00:54:19.360 tendency is if you're under stress of any sort for the testosterone to turn to 00:54:19.360 --> 00:54:26.720 estrogen and the pregnenolone and progesterone will limit that conversion. 00:54:26.720 --> 00:54:34.200 Okay. If you have access to either those both of those can be can be 00:54:34.200 --> 00:54:40.000 obtained so progesterone and pregnenolone typically for a female 00:54:40.000 --> 00:54:43.360 anyway they would normally be producing them and I don't know exactly the 00:54:43.360 --> 00:54:47.080 details of the case and how the transgender nature of this subject is 00:54:47.080 --> 00:54:53.400 either affected adversely or positively so in terms of their exposure to their 00:54:53.400 --> 00:54:57.760 own natural progesterone being female and and or supplementing with 00:54:57.760 --> 00:55:02.080 pregnenolone then that will offset the potentially negative effects that may 00:55:02.080 --> 00:55:05.280 occur with using testosterone in a female. Because it could convert to 00:55:05.280 --> 00:55:09.920 estrogen and become dangerously out of balance. And watching thyroid function. 00:55:09.920 --> 00:55:14.400 Uh-huh okay. All right well thanks for your call we better take this next question. Thank you for your help. 00:55:14.400 --> 00:55:18.280 You're welcome. Okay so caller we've got about three minutes if you can get your 00:55:18.280 --> 00:55:21.280 question out to the doctor here and do it in three minutes and get a response 00:55:21.280 --> 00:55:28.880 we'll wrap the show up. Where are you from? Are they there? Hey caller you on the air? 00:55:28.880 --> 00:55:32.600 All right we had the second call Dr. Peat but never mind because we've only got 00:55:32.600 --> 00:55:39.560 five minutes left so okay. All right I don't even know if we've got time to 00:55:39.560 --> 00:55:43.480 perhaps ask another ask another question without running out of time but I'll 00:55:43.480 --> 00:55:48.400 try here and I think we'll definitely open this up again next month if 00:55:48.400 --> 00:55:51.360 you are available because I've hardly got any questions asked here because 00:55:51.360 --> 00:55:55.560 we've had so many callers and that's a good thing. I wanted to ask you again and 00:55:55.560 --> 00:56:00.760 with them I guess again we get the female issue in estrogen and inflammation 00:56:00.760 --> 00:56:09.440 and cancers etc are pretty obvious as definite definite realities here. In 00:56:09.440 --> 00:56:14.840 terms of the effect of iodide uptake by thyroid cells and the inhibitory effects 00:56:14.840 --> 00:56:19.240 that estrogen has on that in a female again would you be typically just 00:56:19.240 --> 00:56:23.800 wanting to lower estrogenic burden by offsetting that with progesterone and 00:56:23.800 --> 00:56:30.480 pregnenolone and/or thyroid? Yeah thyroid and good adequate nutrition all the 00:56:30.480 --> 00:56:39.160 vitamins and minerals are involved in controlling keeping estrogen under the 00:56:39.160 --> 00:56:48.600 safe safe limit and the when you inhibit the formation of thyroid hormone either 00:56:48.600 --> 00:56:56.080 with an iodine deficiency or an estrogen excess the thyroid stimulating hormone 00:56:56.080 --> 00:57:04.360 fails to make the thyroxine and T3 and so it keeps stimulating not only the 00:57:04.360 --> 00:57:12.160 thyroid gland making it grow and get bigger or nod nodules to form but it has 00:57:12.160 --> 00:57:17.960 a related effect on every tissue to some extent especially the ovaries 00:57:17.960 --> 00:57:26.040 polycystic ovarian syndrome is associated with low thyroid and 00:57:26.040 --> 00:57:34.600 especially high TSH. TSH drives inflammation so that the so-called 00:57:34.600 --> 00:57:41.640 autoimmune conditions associated with high estrogen women are far more 00:57:41.640 --> 00:57:49.880 susceptible to all types of autoimmune diseases than males and that's largely 00:57:49.880 --> 00:57:58.360 because of the high TSH exposure driving things like tumor necrosis factor and 00:57:58.360 --> 00:58:05.280 the various cytokines and interleukins and prostaglandins that are activated. 00:58:05.280 --> 00:58:09.240 Excellent I don't want to cut you short Dr. Peat and I really appreciate your 00:58:09.240 --> 00:58:13.400 your knowledge as do I know all the people that have tuned in and taken the 00:58:13.400 --> 00:58:18.760 time to listen and call from all over so a really really good show from all over 00:58:18.760 --> 00:58:22.560 the country I appreciate people calling. Dr. Peat's website let me just sign off 00:58:22.560 --> 00:58:26.080 giving out your information Dr. Peat so people can find out more. Unless there 00:58:26.080 --> 00:58:30.960 was any last words you wanted to say Dr. Peat. Okay thank you. Thanks so much. 00:58:30.960 --> 00:58:39.080 Okay so Dr. Peat has a pretty extensive referenced library in some ways 00:58:39.080 --> 00:58:45.800 of symptoms and diseases and the mainstream science is argued against 00:58:45.800 --> 00:58:52.600 with real science so the objective science of non-profiteering 00:58:52.600 --> 00:58:57.320 organizations is bought out so much of the details that you'll find there and 00:58:57.320 --> 00:59:02.120 listed in the fully referenced sections that come with each article on thyroid 00:59:02.120 --> 00:59:08.240 hormones, saturated fats, regular hormones, pregnenolone, estradiol, whether it's salt 00:59:08.240 --> 00:59:12.240 or sugar or cholesterol any of the other articles that he's done is a whole range 00:59:12.240 --> 00:59:17.960 of them fully referenced his website www.raypeat.com it's one minute to the 00:59:17.960 --> 00:59:22.680 hour my name is Andrew. My name is Sarah Johanneson Murray. And we can be reached 00:59:22.680 --> 00:59:29.760 at westernbotanicalmedicine.com or you can call an 800 number 1-888-WBM-ERB 00:59:29.760 --> 00:59:35.800 925. Thanks for your time and again next month we'll bring out more questions for 00:59:35.800 --> 00:59:41.120 the doctor and they'll be contrary to public and regular opinion which is 00:59:41.120 --> 00:59:43.640 always a good thing to give you the alternative then you can make your mind 00:59:43.640 --> 00:59:46.880 up. The facts are out there if you want to look for them. Okay good night. Thank 00:59:46.880 --> 00:59:49.280 you for listening. 00:59:49.280 --> 00:59:58.360 [Music]