WEBVTT 00:00:00.000 --> 00:00:09.320 When PUFA is present and oxidation is going on, you're tending to be torn up with free radical lipid peroxidation and such. 00:00:09.500 --> 00:00:17.680 So the PUFA does feed oxidation and can help with weight loss, but that turns out to be almost purely destructive. 00:00:17.920 --> 00:00:19.680 You don't want to lose weight that way. 00:00:32.920 --> 00:00:33.340 The excess of thyroid, when you have a moderate excess of thyroid and DHEA, which increase the wasteful use of oxygen, that waste is protective. 00:00:46.060 --> 00:00:46.340 Animals which are uncoupled, and especially those which have a low PUFA in their tissues, are longer lived. 00:00:52.860 --> 00:01:00.120 The saturation index, if an animal's fats are highly saturated, it has a longer life. 00:01:00.120 --> 00:01:02.640 And that means that it can run its oxidative metabolism at a much higher rate being uncoupled and living longer because its fats aren't set to explode or catch fire with the free radical activity going on.