WEBVTT 00:00:01.000 --> 00:00:08.320 Alright, we should be on the air with Dr. Raymond Peat. This is Politics and Science. I am the host, John Barkhausen, and 00:00:08.320 --> 00:00:11.560 today we're going to be talking about 00:00:11.560 --> 00:00:18.600 human health and the physiological implications of some of the chemical processes that happen in the body, 00:00:18.600 --> 00:00:22.520 namely 00:00:22.520 --> 00:00:26.120 reduction and oxidation and some of the other factors. 00:00:27.180 --> 00:00:31.560 My guest today is Dr. Raymond Peat. He has a PhD in biology and 00:00:31.560 --> 00:00:36.000 speciality in physiology, and Ray, do you want to add anything to that? 00:00:36.000 --> 00:00:39.520 Yeah, when I was studying 00:00:39.520 --> 00:00:43.880 for my degree at University of Oregon, I 00:00:43.880 --> 00:00:51.040 got interested in oxidative processes as they relate to aging and 00:00:51.040 --> 00:00:55.080 I've 00:00:55.080 --> 00:00:57.080 been thinking about 00:00:57.260 --> 00:01:00.480 what oxidation means and all the ramifications 00:01:00.480 --> 00:01:03.300 for 40 or 50 years and 00:01:03.300 --> 00:01:06.340 still 00:01:06.340 --> 00:01:08.540 curious how it really works. 00:01:08.540 --> 00:01:11.860 I see, so it's an ongoing 00:01:11.860 --> 00:01:13.980 scientific 00:01:13.980 --> 00:01:15.980 endeavor, I suppose, understanding it. 00:01:15.980 --> 00:01:21.220 Yeah, the idea of electrons moving around in matter, 00:01:21.220 --> 00:01:24.860 that's one of my longest-standing 00:01:25.980 --> 00:01:30.340 interests. I think it started when I was a little kid probably, but 00:01:30.340 --> 00:01:33.100 I'm still not satisfied that 00:01:33.100 --> 00:01:40.460 anyone knows what an electron is or how it works, but without knowing that you really don't understand 00:01:40.460 --> 00:01:43.860 what's going on in oxidation, reduction, pH, 00:01:43.860 --> 00:01:50.100 free radicals, and so on. Yeah, maybe you could give us a little sense of the history of 00:01:50.100 --> 00:01:52.860 people trying to understand 00:01:53.820 --> 00:01:56.540 chemistry. How did it all start, do you think? 00:01:56.540 --> 00:02:00.740 Well, 00:02:00.740 --> 00:02:09.060 the famous first demonstration that life processes are 00:02:09.060 --> 00:02:16.020 material chemistry was when a guy synthesized urea and 00:02:16.020 --> 00:02:19.500 people had believed that that was 00:02:20.340 --> 00:02:27.540 maybe done by something special in the life process that couldn't be imitated in the real 00:02:27.540 --> 00:02:30.500 inert world, but 00:02:30.500 --> 00:02:33.060 just heating 00:02:33.060 --> 00:02:35.260 things up on the end and 00:02:35.260 --> 00:02:39.860 carbon dioxide, I don't remember the exact chemicals, but 00:02:39.860 --> 00:02:42.660 it was demonstrated that you can make 00:02:42.660 --> 00:02:45.500 urea 00:02:45.500 --> 00:02:47.500 simply mechanically. 00:02:48.420 --> 00:02:50.540 So people started thinking about 00:02:50.540 --> 00:02:58.100 the chemical processes that make up life and 00:02:58.100 --> 00:03:00.980 gradually getting away from the idea that 00:03:00.980 --> 00:03:09.940 there is something unique about the life process that is distinct from chemistry. 00:03:09.940 --> 00:03:17.340 I was just reading about, that was a Swedish person, is that correct, who figured out urea? 00:03:18.180 --> 00:03:23.860 Yeah, and that was I think around the Revolutionary War in 1760-something, 00:03:23.860 --> 00:03:27.860 but people must have experimented with 00:03:27.860 --> 00:03:32.260 bodily fluids before then. Was there much research 00:03:32.260 --> 00:03:35.060 done? 00:03:35.060 --> 00:03:38.500 Yeah, in the 18th century people were really 00:03:38.500 --> 00:03:41.540 figuring out a lot about how 00:03:41.540 --> 00:03:43.700 organisms work, 00:03:43.700 --> 00:03:45.980 but the 00:03:46.980 --> 00:03:48.980 official science, 00:03:48.980 --> 00:03:52.660 stuff that got published and approved of by the government, 00:03:52.660 --> 00:03:55.660 that was a very slow 00:03:55.660 --> 00:03:59.340 process that was 00:03:59.340 --> 00:04:05.140 usually a hundred years behind the people on the ground who were really thinking about how things work. 00:04:05.140 --> 00:04:11.740 I mean science for a large part, this is my understanding, was actually a private affair 00:04:12.380 --> 00:04:17.100 done by usually wealthy people sometimes, or not always I suppose, but... 00:04:17.100 --> 00:04:19.660 Yeah, rich 00:04:19.660 --> 00:04:22.380 cranks. 00:04:22.380 --> 00:04:26.540 So they often put their particular 00:04:26.540 --> 00:04:29.620 philosophical or religious 00:04:29.620 --> 00:04:31.500 bent 00:04:31.500 --> 00:04:33.980 into the physical ideas and 00:04:33.980 --> 00:04:38.860 it was because of that personal quality 00:04:38.860 --> 00:04:41.060 science 00:04:41.060 --> 00:04:43.060 was really 00:04:43.060 --> 00:04:48.260 more literary and interesting and artistic 00:04:48.260 --> 00:04:52.020 before the universities took it over and 00:04:52.020 --> 00:04:57.340 gradually in physics, I guess the universities 00:04:57.340 --> 00:04:59.860 took 00:04:59.860 --> 00:05:04.340 control of it away from the cranks and rich guys 00:05:04.340 --> 00:05:07.020 in the mid-19th century. 00:05:08.060 --> 00:05:12.540 And that was the physics that Einstein, for example, 00:05:12.540 --> 00:05:15.940 being 00:05:15.940 --> 00:05:17.420 the 00:05:17.420 --> 00:05:18.620 leading 00:05:18.620 --> 00:05:21.660 academic physics was being done in Germany and 00:05:21.660 --> 00:05:24.540 Einstein being Jewish 00:05:24.540 --> 00:05:27.220 resented the 00:05:27.220 --> 00:05:30.500 authoritarian dogma of the professors and 00:05:30.500 --> 00:05:33.300 so he invented something that 00:05:33.300 --> 00:05:35.780 outwitted 00:05:36.580 --> 00:05:38.580 authoritarian physics establishment. 00:05:38.580 --> 00:05:40.700 He sure did. 00:05:40.700 --> 00:05:42.700 Boy, and 00:05:42.700 --> 00:05:46.300 yeah, that sort of reminds me of what a general law of 00:05:46.300 --> 00:05:50.820 institutionalization that I'm making up here on the spot, but it seems like it takes the 00:05:50.820 --> 00:05:55.660 the interest out of most fields once it gets franchised like that. 00:05:55.660 --> 00:06:01.220 I mean religion I think used to be more of a personal experience before the church took over and 00:06:01.220 --> 00:06:03.820 it sounds like it's the same with science. 00:06:04.540 --> 00:06:07.860 Yeah, and I think Einstein 00:06:07.860 --> 00:06:11.020 himself succumbed somewhat to 00:06:11.020 --> 00:06:14.700 authoritarian attitudes 00:06:14.700 --> 00:06:18.780 in the case of saying what an electron is and 00:06:18.780 --> 00:06:22.060 30 years later, I think he regretted 00:06:22.060 --> 00:06:24.740 having 00:06:24.740 --> 00:06:28.340 set things in motion in that particular direction when he 00:06:28.340 --> 00:06:31.860 never accepted the 00:06:32.300 --> 00:06:37.820 quantum mechanics view of reality as based on on randomness and 00:06:37.820 --> 00:06:41.740 but he was 00:06:41.740 --> 00:06:47.740 largely responsible for setting that in motion with his theory of the photoelectric effect 00:06:47.740 --> 00:06:51.140 and the 00:06:51.140 --> 00:06:54.420 idea of the electron as a discrete particle 00:06:54.420 --> 00:06:58.980 interacting with a photon as a discrete particle 00:06:58.980 --> 00:07:01.020 was 00:07:01.020 --> 00:07:04.340 the key idea in that photoelectric effect 00:07:04.340 --> 00:07:09.180 a photon of a given energy would 00:07:09.180 --> 00:07:12.060 dislodge 00:07:12.060 --> 00:07:14.900 an electron from the 00:07:14.900 --> 00:07:17.980 solid state 00:07:17.980 --> 00:07:23.100 giving it a certain voltage and so you can talk about the electron 00:07:23.100 --> 00:07:29.420 energy or voltage of a given frequency of light and 00:07:30.580 --> 00:07:32.500 that 00:07:32.500 --> 00:07:37.300 particularized or atomized the idea of both light and electrons 00:07:37.300 --> 00:07:41.340 and that's that's something that 00:07:41.340 --> 00:07:49.020 Allowed theory to take over and cover up and 00:07:49.020 --> 00:07:52.380 reject a lot of 00:07:52.380 --> 00:07:55.020 empirical factual 00:07:55.020 --> 00:07:56.260 observation 00:07:56.260 --> 00:07:58.300 relating to light color 00:07:59.140 --> 00:08:02.340 electrons molecules and so on and I think life 00:08:02.340 --> 00:08:04.100 Wow 00:08:04.100 --> 00:08:10.380 So that's interesting. Once you become an icon you have to be very careful what you say because people might take you seriously 00:08:10.380 --> 00:08:15.420 Yeah, I don't know how conscious he was of that but 00:08:15.420 --> 00:08:18.660 he was 00:08:18.660 --> 00:08:22.300 Very persistent in 00:08:22.300 --> 00:08:24.460 not 00:08:24.460 --> 00:08:30.380 Fundamentally going along with with the drift of the quantum physics establishment 00:08:30.380 --> 00:08:35.660 so so that that view of the electron and 00:08:35.660 --> 00:08:41.460 Is atoms in general I imagine seeing the electron is an essential part of 00:08:41.460 --> 00:08:44.420 atomic structure 00:08:44.420 --> 00:08:48.500 How can you explain further how that actually set us on the wrong track? 00:08:48.500 --> 00:08:52.620 Yeah 00:08:53.220 --> 00:08:59.100 You know around the time of the First World War Michael Polanyi had demonstrated a 00:08:59.100 --> 00:09:02.460 continuous potential 00:09:02.460 --> 00:09:11.260 Description of how gases are bound or absorbed on the solid surfaces and 00:09:11.260 --> 00:09:17.900 That that was a smooth sort of process a straight 00:09:20.220 --> 00:09:25.540 Relationship between the pressure on the gas and the thickness of the absorbed layer and 00:09:25.540 --> 00:09:32.900 When he went to Berlin to present his experimental work and theory 00:09:32.900 --> 00:09:36.020 Einstein and others 00:09:36.020 --> 00:09:41.460 that was already 10 years beyond the photoelectric theory and the 00:09:41.460 --> 00:09:44.300 particularization of 00:09:44.300 --> 00:09:45.820 light 00:09:45.820 --> 00:09:47.820 electron 00:09:48.660 --> 00:09:50.660 Energy or structure and 00:09:50.660 --> 00:09:53.460 Einstein was one of the people that said 00:09:53.460 --> 00:09:55.580 in 00:09:55.580 --> 00:09:58.900 the advanced science world here in Germany 00:09:58.900 --> 00:10:02.780 we know that that just isn't possible because 00:10:02.780 --> 00:10:07.980 Matter is particular and you're just aren't going to get forces 00:10:07.980 --> 00:10:12.940 Smoothly extending away from the surface 00:10:12.940 --> 00:10:15.980 if the 00:10:15.980 --> 00:10:21.580 Surface has an electrical property and the gas has an electrical property 00:10:21.580 --> 00:10:30.620 the first layer of gas atoms hitting that surface is going to perfectly neutralize that so there's no 00:10:30.620 --> 00:10:33.220 potential 00:10:33.220 --> 00:10:35.380 extending through space but 00:10:35.380 --> 00:10:37.820 Polanyi's results 00:10:37.820 --> 00:10:41.540 Clearly showed that something like that was happening a continuously 00:10:41.540 --> 00:10:44.420 thickening layer 00:10:45.020 --> 00:10:46.780 and 00:10:46.780 --> 00:10:49.340 So Polanyi was defeated 00:10:49.340 --> 00:10:51.700 the 00:10:51.700 --> 00:10:53.700 people like Irving Langmuir 00:10:53.700 --> 00:10:58.740 15 years later got the Nobel Prize for 00:10:58.740 --> 00:11:01.420 his idea that 00:11:01.420 --> 00:11:04.300 gases can only condensed in a monolayer 00:11:04.300 --> 00:11:07.460 And 00:11:07.460 --> 00:11:11.220 Polanyi knew it was wrong, but he was a physics professor and 00:11:11.780 --> 00:11:14.660 He had to teach the Langmuir 00:11:14.660 --> 00:11:16.980 isotherm 00:11:16.980 --> 00:11:21.180 but in his own experimental work Polanyi 00:11:21.180 --> 00:11:28.500 Went along examining how molecules and crystals solid-state things 00:11:28.500 --> 00:11:31.580 work and 00:11:31.580 --> 00:11:34.100 in one 00:11:34.100 --> 00:11:38.180 Area of research after another he kept seeing 00:11:39.580 --> 00:11:42.180 Continuity things extending 00:11:42.180 --> 00:11:44.540 for example 00:11:44.540 --> 00:11:49.180 in the behavior of a crystal where previously he had shown that 00:11:49.180 --> 00:11:52.300 gases on the surface of 00:11:52.300 --> 00:11:55.900 activated charcoal for example for multi layers 00:11:55.900 --> 00:12:02.640 Working with crystals. He found that the events on the surface of a crystal 00:12:02.640 --> 00:12:07.700 Affected its elasticity and resistance all the way through 00:12:09.180 --> 00:12:10.860 so 00:12:10.860 --> 00:12:12.700 physically 00:12:12.700 --> 00:12:18.660 The surface doesn't doesn't have the meaning that it seems to in geometry 00:12:18.660 --> 00:12:22.780 And for example in 00:12:22.780 --> 00:12:28.340 Working a crystal back and forth it gets weaker and weaker 00:12:28.340 --> 00:12:31.540 as as it 00:12:31.540 --> 00:12:33.260 accumulates 00:12:33.260 --> 00:12:36.220 some kind of fatigue or memory and 00:12:38.740 --> 00:12:40.740 J.C. Bose had 00:12:40.740 --> 00:12:43.180 demonstrated that sort of thing and 00:12:43.180 --> 00:12:49.340 found that the fatigue could be recovered from in a crystal, but 00:12:49.340 --> 00:12:52.500 Polanyi was interested in the fact that 00:12:52.500 --> 00:12:55.420 The 00:12:55.420 --> 00:12:56.900 weakening 00:12:56.900 --> 00:12:58.900 involves energy 00:12:58.900 --> 00:13:01.380 flowing over long distances 00:13:01.380 --> 00:13:03.900 creating 00:13:03.900 --> 00:13:05.900 areas of 00:13:05.900 --> 00:13:07.940 exaggerated weakness and 00:13:08.940 --> 00:13:12.700 That was the same sort of effect that he saw 00:13:12.700 --> 00:13:17.260 When the surface of a crystal was wet 00:13:17.260 --> 00:13:20.700 the surface effect 00:13:20.700 --> 00:13:28.500 Modified the resistance and elasticity properties of the depth of the crystal 00:13:28.500 --> 00:13:32.020 So it was 00:13:32.700 --> 00:13:37.980 Analogous probably to the the idea of conduction bands in which in metal 00:13:37.980 --> 00:13:41.740 the electrons are delocalized and 00:13:41.740 --> 00:13:49.620 The you can think of particulate electrons 00:13:49.620 --> 00:13:52.940 acting this way, but 00:13:52.940 --> 00:13:56.140 Polanyi's work suggested that maybe 00:13:56.140 --> 00:14:01.700 That isn't the the only or necessary way to think of electrons 00:14:02.420 --> 00:14:03.940 and 00:14:03.940 --> 00:14:05.420 in 00:14:05.420 --> 00:14:07.420 When I was in graduate school 00:14:07.420 --> 00:14:11.100 1969 or 70 I was 00:14:11.100 --> 00:14:13.460 reading 00:14:13.460 --> 00:14:16.020 surface physics, especially 00:14:16.020 --> 00:14:20.700 as a way to help understand oxidation 00:14:20.700 --> 00:14:25.740 Biologically and in one of the physics journals 00:14:25.740 --> 00:14:30.260 A man named Helmut Schwart 00:14:31.460 --> 00:14:35.140 published a description of a funny experiment 00:14:35.140 --> 00:14:39.500 In which laser light is shined 00:14:39.500 --> 00:14:42.620 horizontally through a crystal 00:14:42.620 --> 00:14:45.180 while a beam of electrons 00:14:45.180 --> 00:14:47.940 goes through the other 00:14:47.940 --> 00:14:50.860 dimension of the crystal through the thin 00:14:50.860 --> 00:14:54.500 Layer 00:14:54.500 --> 00:14:59.380 A layer about less than a micron half a micron or so thick 00:15:00.180 --> 00:15:02.180 and the 00:15:02.180 --> 00:15:09.300 Electrons passing through the crystal are deflected into a certain pattern 00:15:09.300 --> 00:15:15.940 Either by the electronic property of the crystal atoms that they pass by 00:15:15.940 --> 00:15:18.940 so you can see the 00:15:18.940 --> 00:15:24.500 shape of the crystal reflected in the image of where the electrons hit but 00:15:24.500 --> 00:15:28.260 Ordinarily that's done exposing 00:15:29.260 --> 00:15:31.700 electrons passing through the crystal 00:15:31.700 --> 00:15:38.180 Exposing a piece of photographic film to the electrons and getting a chemical 00:15:38.180 --> 00:15:43.060 Change producing the image, but he found taking 00:15:43.060 --> 00:15:49.100 Even a fluorescent screen away putting an aluminum oxide 00:15:49.100 --> 00:15:55.300 Coated layer at the bottom that was very non reflective 00:15:56.900 --> 00:16:03.180 He found that the electron spots were still there, but they had the blue tint 00:16:03.180 --> 00:16:08.140 of the laser light going sideways through the crystal and 00:16:08.140 --> 00:16:11.700 so the spots had to be 00:16:11.700 --> 00:16:14.740 the supposedly discrete 00:16:14.740 --> 00:16:16.660 particulate 00:16:16.660 --> 00:16:19.300 electrons for them to be 00:16:19.300 --> 00:16:22.580 deflected 00:16:22.580 --> 00:16:25.380 To exactly the right spots 00:16:26.740 --> 00:16:28.740 Which are used to 00:16:28.740 --> 00:16:31.380 identify crystal structures and such 00:16:31.380 --> 00:16:38.100 but at that spot there shouldn't have been any light, but it was 00:16:38.100 --> 00:16:41.300 the color of the laser light 00:16:41.300 --> 00:16:48.740 Modulating in fact the the beam of electrons and 00:16:48.740 --> 00:16:51.100 that 00:16:51.100 --> 00:16:52.340 when I 00:16:52.340 --> 00:16:59.020 Tried to talk to physics professors about it. They simply said it can't happen you can't modulate 00:16:59.020 --> 00:17:00.980 one electron 00:17:00.980 --> 00:17:05.180 Mm-hmm, and when you say modulate you mean change color or actually yeah 00:17:05.180 --> 00:17:08.660 Yeah, the color of an electron is supposed to be its relationship 00:17:08.660 --> 00:17:12.860 to the atom and what it's doing is is 00:17:12.860 --> 00:17:16.100 absorbing or 00:17:16.100 --> 00:17:18.300 interacting with a particular 00:17:19.020 --> 00:17:22.060 wavelength of the light so the atom is 00:17:22.060 --> 00:17:25.260 subtracting or maybe 00:17:25.260 --> 00:17:27.940 fluorescing a color, but it's always 00:17:27.940 --> 00:17:35.740 Subtracting or adding something according to the way it is bound to the atom 00:17:35.740 --> 00:17:39.420 So an electron flying through space 00:17:39.420 --> 00:17:43.900 It just wasn't acceptable 00:17:43.900 --> 00:17:48.100 They preferred to say that the person was simply 00:17:48.700 --> 00:17:50.700 Hallucinating or something? 00:17:50.700 --> 00:17:53.820 But it was it done at 00:17:53.820 --> 00:17:57.260 Rensselaer Polytechnic Institute and 00:17:57.260 --> 00:18:00.260 They had the best equipment 00:18:00.260 --> 00:18:04.740 of that sort in the world at the time Wow and 00:18:04.740 --> 00:18:08.540 a lot of people immediately trying to 00:18:08.540 --> 00:18:11.220 replicate it 00:18:11.220 --> 00:18:13.220 Didn't have the same 00:18:13.220 --> 00:18:15.780 degree of vacuum in their 00:18:16.420 --> 00:18:20.260 Electron microscope or didn't have the same power of laser 00:18:20.260 --> 00:18:24.020 Or or the same quality of crystal making and so on 00:18:24.020 --> 00:18:27.180 great cleanliness and so on 00:18:27.180 --> 00:18:33.540 Was part of the original experiment. So a lot of people assert like cold fusion 00:18:33.540 --> 00:18:36.060 Mm-hmm 00:18:36.060 --> 00:18:41.260 If it violates the theory and you don't have the same equipment exactly 00:18:41.260 --> 00:18:44.020 It's very easy to 00:18:44.020 --> 00:18:45.940 debunk 00:18:45.940 --> 00:18:53.860 Something just by by doing a slightly different setup and getting different results. Yeah, that's right today's genius 00:18:53.860 --> 00:18:58.060 Well, actually today's crackpot is possibly tomorrow's genius 00:18:58.060 --> 00:19:00.540 in many cases 00:19:00.540 --> 00:19:02.180 very recently 00:19:02.180 --> 00:19:04.220 Helmut Schwarz who became 00:19:04.220 --> 00:19:07.020 the head of Germany's 00:19:07.020 --> 00:19:09.820 research granting 00:19:09.820 --> 00:19:11.140 institution 00:19:11.140 --> 00:19:14.520 the government's money dispenser for research 00:19:15.460 --> 00:19:17.460 he said that 00:19:17.460 --> 00:19:21.180 Outsiders are important everywhere. Not just in science 00:19:21.180 --> 00:19:26.000 You don't get advanced unless you have people 00:19:26.000 --> 00:19:33.180 Somewhat on the fringe. Yeah, if anybody wants to Google minority opinions in science 00:19:33.180 --> 00:19:35.620 There's actually a huge amount of information out there 00:19:35.620 --> 00:19:39.900 Scientists who have been sidelined for their 00:19:39.900 --> 00:19:44.620 viable research but because it's bucking the current 00:19:45.620 --> 00:19:49.620 Institutions or the money that's coming into those institutions. They're not getting any 00:19:49.620 --> 00:19:54.860 Traction with any of their work and in fact a lot of the research is being taken away from them 00:19:54.860 --> 00:19:57.780 research facilities, so 00:19:57.780 --> 00:20:00.380 It's a it's a lot bigger 00:20:00.380 --> 00:20:05.100 Faction of science than anybody hears about because of course they don't get any press either 00:20:05.100 --> 00:20:10.380 And I've been noticing that 00:20:11.940 --> 00:20:13.940 Institutions like the Wikipedia 00:20:13.940 --> 00:20:19.220 Supposedly the Internet should be an opportunity to 00:20:19.220 --> 00:20:23.900 Disseminate 00:20:23.900 --> 00:20:26.020 Dissenting ideas, but 00:20:26.020 --> 00:20:27.980 the 00:20:27.980 --> 00:20:29.780 culture of 00:20:29.780 --> 00:20:32.920 Authoritarian science is so strong that you see it 00:20:32.920 --> 00:20:37.460 affecting the way Wikipedia works, it's sort of like a 00:20:37.460 --> 00:20:40.180 sounding board for the 00:20:41.220 --> 00:20:43.220 most authoritarian 00:20:43.220 --> 00:20:45.980 Viewpoints in science 00:20:45.980 --> 00:20:52.460 Yeah, and that makes sense because if you have the money of an institution behind you you have the money to pay a staff member 00:20:52.460 --> 00:20:55.440 to keep updating Wikipedia and editing anybody's 00:20:55.440 --> 00:20:57.820 other 00:20:57.820 --> 00:20:59.300 input 00:20:59.300 --> 00:21:03.300 So it's it's kind of like he who has the most resources wins 00:21:03.300 --> 00:21:09.860 Yeah the argument so I was a little confused about the particulate 00:21:10.860 --> 00:21:17.300 Electrons versus the is it a wave theory is the alternative or one of the alternatives to that? 00:21:17.300 --> 00:21:19.660 What's wrong with the particles? 00:21:19.660 --> 00:21:22.220 well you 00:21:22.220 --> 00:21:24.740 Since you can't explain 00:21:24.740 --> 00:21:28.460 Many events in terms of particles 00:21:28.460 --> 00:21:37.360 It becomes a sort of mathematical magic to try to make up 00:21:38.620 --> 00:21:40.620 theories to explain 00:21:40.620 --> 00:21:44.580 results like Polanyi or Schwart's and 00:21:44.580 --> 00:21:49.500 Albert Szent-Gyorgyi used 00:21:49.500 --> 00:21:52.700 conventional 00:21:52.700 --> 00:21:57.020 Quantum thinking about electrons and 00:21:57.020 --> 00:22:02.500 went went a long way towards explaining as some of the 00:22:02.500 --> 00:22:06.700 Biological phenomena that people hadn't been able to 00:22:07.860 --> 00:22:09.860 even perceive 00:22:09.860 --> 00:22:17.140 But that doesn't mean that that it necessarily validates the the particulate 00:22:17.140 --> 00:22:22.740 Electron just because you you can explain some 00:22:22.740 --> 00:22:27.740 important phenomena and so I think it should mean that 00:22:27.740 --> 00:22:31.620 The whole idea of 00:22:31.620 --> 00:22:34.100 What matter is how an electron? 00:22:34.100 --> 00:22:36.260 works whether 00:22:36.620 --> 00:22:38.620 It might be that 00:22:38.620 --> 00:22:40.740 There is an electrical 00:22:40.740 --> 00:22:46.140 Ether like material which breaks up in different ways 00:22:46.140 --> 00:22:49.560 Into 00:22:49.560 --> 00:22:52.300 Apparently discrete electrons, but 00:22:52.300 --> 00:23:00.580 That rather than being an eternally discrete particle like a proton is supposed to be 00:23:00.580 --> 00:23:03.740 The electron might be sort of an ad hoc 00:23:05.940 --> 00:23:07.700 Interpretation 00:23:07.700 --> 00:23:09.700 which the 00:23:09.700 --> 00:23:12.100 wave interpretation 00:23:12.100 --> 00:23:14.820 Is approaching that idea? 00:23:14.820 --> 00:23:17.220 that the 00:23:17.220 --> 00:23:19.140 and some of the 00:23:19.140 --> 00:23:21.020 subatomic 00:23:21.020 --> 00:23:24.740 Thinkers are saying that maybe this great variety of 00:23:24.740 --> 00:23:30.020 Subatomic particles being seen with high energy research maybe 00:23:30.020 --> 00:23:32.780 These are just sort of an ad hoc 00:23:32.780 --> 00:23:35.380 response of 00:23:35.700 --> 00:23:37.700 Matter to a particular 00:23:37.700 --> 00:23:41.820 context or environment or or stimulation. Mm-hmm 00:23:41.820 --> 00:23:49.380 So it might just be an aspect you're seeing depending on the the medium you're using to see it with. Yeah, exactly 00:23:49.380 --> 00:23:51.220 see 00:23:51.220 --> 00:23:53.220 and that would say that 00:23:53.220 --> 00:24:00.740 In a different solar system or a different galaxy the atoms are not necessarily 00:24:00.740 --> 00:24:03.900 Going to be the same 00:24:04.220 --> 00:24:05.700 exact 00:24:05.700 --> 00:24:07.700 have the same functionality and 00:24:07.700 --> 00:24:12.940 That is an implication of Halton Arp's 00:24:12.940 --> 00:24:17.820 Comments on his galaxy photographs 00:24:17.820 --> 00:24:23.380 Okay, now that you brought that up you better explain what that means again 00:24:23.380 --> 00:24:28.100 the he showed that 00:24:28.100 --> 00:24:32.340 What appeared to be 00:24:33.820 --> 00:24:36.180 Continuously connected 00:24:36.180 --> 00:24:40.100 Groups of stars 00:24:40.100 --> 00:24:43.020 One of the parts 00:24:43.020 --> 00:24:45.540 Of what seems to be a continuous? 00:24:45.540 --> 00:24:49.580 Stream of stars one of the parts will have 00:24:49.580 --> 00:24:55.880 an extreme redshift difference from the other one meaning that they should be 00:24:55.880 --> 00:24:58.900 very remote in space, but 00:24:58.900 --> 00:25:01.740 his pictures show 00:25:01.980 --> 00:25:08.180 Connections like one is being shot out of the other and he suggests that the one being shot out is 00:25:08.180 --> 00:25:11.580 newly created and the new matter 00:25:11.580 --> 00:25:15.260 Has a different way of vibrating 00:25:15.260 --> 00:25:19.660 Which shows up as a redshift in other words? 00:25:19.660 --> 00:25:23.500 The atoms are different when when they're fresh I 00:25:23.500 --> 00:25:28.980 See and and you said I think last time or that another time we talked that a redshift 00:25:29.140 --> 00:25:32.380 It means something's moving away from you is that in space? 00:25:32.380 --> 00:25:37.860 I said that's the standard mechanical physics connection like the Doppler effect fun 00:25:37.860 --> 00:25:41.940 Passes the frequency drops I 00:25:41.940 --> 00:25:45.780 See so but you're saying it also could have other implications 00:25:45.780 --> 00:25:52.020 Yeah, for example light passing close to a star 00:25:52.020 --> 00:25:56.060 Has a frequency shift and 00:25:57.260 --> 00:25:59.260 an Israeli 00:25:59.260 --> 00:26:05.140 physicist astronomer named Dror Sadeh was working in the US and 00:26:05.140 --> 00:26:08.820 He was 00:26:08.820 --> 00:26:14.940 Studying at different times the light of of a star passing close to the Sun and 00:26:14.940 --> 00:26:18.060 of a 00:26:18.060 --> 00:26:23.260 Beeping quasar pulsar that sends out a certain frequency 00:26:24.500 --> 00:26:27.180 passing close to the Sun and he 00:26:27.180 --> 00:26:30.220 kept seeing what seemed to be a 00:26:30.220 --> 00:26:33.540 time change or a frequency change 00:26:33.540 --> 00:26:38.220 Depending on how close the beam came to the Sun and 00:26:38.220 --> 00:26:40.980 he 00:26:40.980 --> 00:26:42.140 got 00:26:42.140 --> 00:26:47.300 an atomic clock at the US Bureau of Standards and 00:26:47.300 --> 00:26:51.420 mounted another one on the track and 00:26:52.220 --> 00:26:56.500 connected them by radio as so that they could be synchronized and 00:26:56.500 --> 00:27:04.140 Then drove up the coast. I think he went up towards Maine and 00:27:04.140 --> 00:27:08.220 Meanwhile recorded the 00:27:08.220 --> 00:27:15.060 Relationship between these two clocks as he went and saw that 00:27:15.060 --> 00:27:18.180 every morning at sunrise 00:27:19.540 --> 00:27:25.020 Washington DC seemed to be redshifted away from his truck 00:27:25.020 --> 00:27:33.220 And and his argument was that something about the 00:27:33.220 --> 00:27:39.460 Field of the Sun coming on the scene was 00:27:39.460 --> 00:27:43.700 Shifting the radio 00:27:43.700 --> 00:27:48.180 Waves that were connecting the the two clocks 00:27:49.180 --> 00:27:53.500 Otherwise, it would have looked like you had an expanding 00:27:53.500 --> 00:27:57.020 universe to a ridiculous extent in which 00:27:57.020 --> 00:28:00.340 Washington was moving 00:28:00.340 --> 00:28:03.340 Million miles an hour away from Maine 00:28:03.340 --> 00:28:06.820 Well, I think it may be 00:28:06.820 --> 00:28:10.020 They seem remarkably out of touch 00:28:10.020 --> 00:28:12.580 with 00:28:12.580 --> 00:28:14.580 real life anyway 00:28:17.220 --> 00:28:19.300 Well, that's fascinating right and 00:28:19.300 --> 00:28:25.580 and so we're talking about the nature of the universe and ourselves and 00:28:25.580 --> 00:28:28.780 particularly electrons I guess and electrical 00:28:28.780 --> 00:28:31.460 feel so you're saying that the 00:28:31.460 --> 00:28:33.500 that the 00:28:33.500 --> 00:28:35.500 the Sun's 00:28:35.500 --> 00:28:42.580 Electrical field when it or maybe it isn't even electrical but the wave from the Sun of radiation is 00:28:42.580 --> 00:28:44.900 possibly 00:28:44.900 --> 00:28:46.900 altering time slightly 00:28:47.900 --> 00:28:49.900 He I 00:28:49.900 --> 00:28:52.740 Think he was thinking in terms of 00:28:52.740 --> 00:29:01.300 Gravitational field. Oh, but I don't know exactly what sunrise would mean. Okay 00:29:01.300 --> 00:29:08.820 It's in terms of his thinking. How do you spell his name Ray so we could go look up on the internet? 00:29:08.820 --> 00:29:12.940 What he's up to first name D. R. O. R. Okay 00:29:13.940 --> 00:29:20.420 Sadeh S a d e h. Okay. Okay. He was killed in 00:29:20.420 --> 00:29:23.780 radiation poisoning 00:29:23.780 --> 00:29:25.900 in the 00:29:25.900 --> 00:29:28.660 Non-atomic bomb laboratories in Israel. Oh 00:29:28.660 --> 00:29:35.620 Right the non-atomic bomb laboratories making the bombs. They don't have yeah. Yeah 00:29:35.620 --> 00:29:38.900 That's terrible 00:29:42.940 --> 00:29:44.700 So 00:29:44.700 --> 00:29:47.060 Obviously it makes a difference how you think about 00:29:47.060 --> 00:29:53.900 electrons and if you're trying to figure out how these molecular processes are happening and 00:29:53.900 --> 00:29:56.500 This show was going to be about physiology 00:29:56.500 --> 00:30:03.500 But I guess it makes a real difference of what your general theory of atomic structure is 00:30:03.500 --> 00:30:06.460 you know the 00:30:06.460 --> 00:30:08.820 idea of 00:30:08.820 --> 00:30:11.540 Particular nature of matter 00:30:12.700 --> 00:30:18.660 Sort of spread or diffused into the thinking process so that 00:30:18.660 --> 00:30:21.220 atoms 00:30:21.220 --> 00:30:23.220 the same way Einstein 00:30:23.220 --> 00:30:25.260 Couldn't tolerate 00:30:25.260 --> 00:30:27.860 multi-layer adsorption in 1915 00:30:27.860 --> 00:30:33.300 Biochemists can't tolerate long-range 00:30:33.300 --> 00:30:37.860 processes in biochemistry and 00:30:37.860 --> 00:30:41.500 One of the 00:30:42.460 --> 00:30:45.260 Thing things in chemistry that resembled 00:30:45.260 --> 00:30:51.100 What Polanyi was seeing in in crystals and his other? 00:30:51.100 --> 00:30:53.620 experiments 00:30:53.620 --> 00:30:56.340 the inductive effect is 00:30:56.340 --> 00:30:59.660 at the basis of 00:30:59.660 --> 00:31:05.100 Really fundamental biological thinking about 00:31:05.100 --> 00:31:09.660 Coasservate for example 00:31:10.220 --> 00:31:12.220 Bungenberg de Jong 00:31:12.220 --> 00:31:15.420 founded a 00:31:15.420 --> 00:31:17.780 line of thinking that 00:31:17.780 --> 00:31:21.660 Eventually led to a Gilbert Ling's 00:31:21.660 --> 00:31:24.540 way of seeing the 00:31:24.540 --> 00:31:28.940 the cell as a special state of matter and 00:31:28.940 --> 00:31:32.620 One of the 00:31:32.620 --> 00:31:36.540 basic and simple chemical physical principles 00:31:38.180 --> 00:31:40.180 Necessary to think this way is 00:31:40.180 --> 00:31:42.980 called 00:31:42.980 --> 00:31:46.260 electronic induction in the molecule and 00:31:46.260 --> 00:31:48.980 when you have 00:31:48.980 --> 00:31:50.980 atoms that are 00:31:50.980 --> 00:31:59.460 Electron withdrawing or they have an affinity for electrons you put them in the molecule and 00:31:59.460 --> 00:32:02.900 the 00:32:02.900 --> 00:32:07.420 Charge or the intensity of the electrons effect 00:32:08.420 --> 00:32:12.420 Shifts down the molecular chain towards that 00:32:12.420 --> 00:32:16.140 electron withdrawing atom or group 00:32:16.140 --> 00:32:20.700 So it's it's like a partial electron and 00:32:20.700 --> 00:32:29.460 That that's an essential part now of organic chemistry that you have partial charges, but 00:32:29.460 --> 00:32:32.500 when you 00:32:32.500 --> 00:32:35.900 really take that seriously and see that 00:32:37.100 --> 00:32:39.100 this effect 00:32:39.100 --> 00:32:43.580 Exists everywhere in every molecule in the cell 00:32:43.580 --> 00:32:47.860 it goes to another level which is 00:32:47.860 --> 00:32:51.060 the 00:32:51.060 --> 00:32:54.300 Coordinated or coherent 00:32:54.300 --> 00:32:57.580 Effects of 00:32:57.580 --> 00:33:00.780 The 00:33:00.780 --> 00:33:03.420 Electron 00:33:03.420 --> 00:33:06.060 Inducing 00:33:06.220 --> 00:33:08.460 groups, so you you have a 00:33:08.460 --> 00:33:11.460 collective kind of reaction 00:33:11.460 --> 00:33:18.700 And in which you pass a threshold sort of the way liquid water passes to solid water 00:33:18.700 --> 00:33:21.980 They can be at the same temperature, but 00:33:21.980 --> 00:33:27.660 someone has to start the process and and then it can go like a 00:33:27.660 --> 00:33:30.860 cascade all at once the 00:33:31.980 --> 00:33:35.740 Atoms will fall into place. Hmm. You change the state so 00:33:35.740 --> 00:33:38.500 You can have a solid 00:33:38.500 --> 00:33:40.420 water 00:33:40.420 --> 00:33:47.420 at somewhat above the melting temperature or liquid water well below the freezing temperature 00:33:47.420 --> 00:33:50.660 if you don't have this 00:33:50.660 --> 00:33:53.380 cooperativity of 00:33:53.380 --> 00:33:56.060 molecules and atoms and 00:33:56.060 --> 00:33:59.300 when you combine these added 00:34:00.300 --> 00:34:02.300 these ideas of 00:34:02.300 --> 00:34:04.540 cooperativity and 00:34:04.540 --> 00:34:06.900 induction 00:34:06.900 --> 00:34:09.140 You get 00:34:09.140 --> 00:34:13.780 These group effects where you have a change of state in effect 00:34:13.780 --> 00:34:19.100 Which will pass through the bulk of the material 00:34:19.100 --> 00:34:25.100 So that you can start thinking about how it works with 00:34:26.860 --> 00:34:30.740 Looking at the effects of pH on a protein 00:34:30.740 --> 00:34:34.020 okay, but 00:34:34.020 --> 00:34:36.780 That's the simplest 00:34:36.780 --> 00:34:39.660 effect of the 00:34:39.660 --> 00:34:44.540 pH although the same all the way through a solution and the protein 00:34:44.540 --> 00:34:47.820 With its 00:34:47.820 --> 00:34:49.820 various charged groups 00:34:49.820 --> 00:34:51.620 responding to that pH 00:34:51.620 --> 00:34:53.700 so that the internal fields 00:34:53.700 --> 00:34:55.860 are 00:34:55.860 --> 00:35:01.220 Intensified or decreased according to the pH so you can have a protein 00:35:01.220 --> 00:35:04.220 expanding or collapsing according to the 00:35:04.220 --> 00:35:07.620 pH of its surroundings, but 00:35:07.620 --> 00:35:11.180 Then when you add 00:35:11.180 --> 00:35:16.700 Other molecules binding or associating with that protein and 00:35:16.700 --> 00:35:22.700 Those have electron withdrawing or donating properties 00:35:23.900 --> 00:35:28.420 Then the way that protein responds to a certain pH is different. I 00:35:28.420 --> 00:35:31.460 see and 00:35:31.460 --> 00:35:38.060 These electron withdrawing molecules are in a sense a partial 00:35:38.060 --> 00:35:40.700 oxidation 00:35:40.700 --> 00:35:44.340 Oxidation being taking away of electrons. Mm-hmm 00:35:44.340 --> 00:35:49.020 So the 00:35:49.020 --> 00:35:51.180 degree of 00:35:51.180 --> 00:35:53.180 oxidation in a molecule 00:35:53.540 --> 00:35:57.220 defines how electron withdrawing it is and 00:35:57.220 --> 00:35:59.580 the 00:35:59.580 --> 00:36:01.180 totality of 00:36:01.180 --> 00:36:05.140 molecules with that quality in the system such as a 00:36:05.140 --> 00:36:09.620 protein or a group of proteins in the solvent 00:36:09.620 --> 00:36:12.620 that will 00:36:12.620 --> 00:36:18.460 affect the the global degree of oxidation of the system and 00:36:20.580 --> 00:36:24.700 When it reaches a certain point instead of just one protein 00:36:24.700 --> 00:36:30.340 Collapsing or expanding you get the same 00:36:30.340 --> 00:36:32.460 freeze melt 00:36:32.460 --> 00:36:38.180 Transition in which one protein triggers another one and so on. I see 00:36:38.180 --> 00:36:41.340 So you get coherent cooperative 00:36:41.340 --> 00:36:44.620 types of changes throughout the system 00:36:44.620 --> 00:36:49.820 That that's where the 00:36:50.540 --> 00:36:56.620 Tending to think discreetly has been so strongly affected by the 00:36:56.620 --> 00:36:59.740 the 00:36:59.740 --> 00:37:04.860 particulate electron particulate proton particulate photon 00:37:04.860 --> 00:37:07.340 type of thinking 00:37:07.340 --> 00:37:09.340 so that people don't like to 00:37:09.340 --> 00:37:12.140 get involved in those 00:37:12.140 --> 00:37:14.820 cooperative global effects I 00:37:14.820 --> 00:37:17.380 see, so I 00:37:17.620 --> 00:37:24.700 Don't know if I'm gonna probably got this confused, but it sounds like there's several things that affect how quickly a chemical change happens 00:37:24.700 --> 00:37:30.300 In the body or elsewhere and that one of them is the environment. So the pH surrounding 00:37:30.300 --> 00:37:35.380 The substance where the change might happen is key. And then the other 00:37:35.380 --> 00:37:37.500 part is 00:37:37.500 --> 00:37:40.620 The materials that are attached to that substance 00:37:40.620 --> 00:37:47.500 so if you're telling protein and then the protein might have other molecules attached to it that actually enhance or 00:37:47.660 --> 00:37:49.660 deter the change happening 00:37:49.660 --> 00:37:51.820 yeah, and that's 00:37:51.820 --> 00:37:54.540 one of the complexities of 00:37:54.540 --> 00:37:57.100 the living stages that 00:37:57.100 --> 00:37:59.460 It if you kill it 00:37:59.460 --> 00:38:01.820 It doesn't work the same 00:38:01.820 --> 00:38:05.460 So you have to think of it always in a certain environment 00:38:05.460 --> 00:38:08.620 hmm 00:38:08.620 --> 00:38:15.860 That you have to really think of it as a flow from from the environment 00:38:16.660 --> 00:38:18.460 in and out 00:38:18.460 --> 00:38:22.260 And the rate of flow and intensity of flow and so on 00:38:22.260 --> 00:38:31.700 The the way people think about antioxidants even tends to 00:38:31.700 --> 00:38:39.180 Turn into a static description rather than a flowing process 00:38:39.180 --> 00:38:42.620 L is is always when it's alive 00:38:44.100 --> 00:38:50.020 Maintaining a delicate balance between oxidation and and reduction and so 00:38:50.020 --> 00:38:57.420 Antioxidants are a dynamic process in which they're also oxidants 00:38:57.420 --> 00:39:02.060 if they're if you push towards a 00:39:02.060 --> 00:39:08.460 Dominance of reduction then you kill the cell in in a different way 00:39:09.660 --> 00:39:17.460 Ray can you back up a little bit and just explain the origin of the word oxidant and and and what it means? 00:39:17.460 --> 00:39:20.220 um 00:39:20.220 --> 00:39:25.420 In the 18th century when they were thinking of phlogiston 00:39:25.420 --> 00:39:30.180 That you had to deflogisticate 00:39:30.180 --> 00:39:33.700 Something what does that mean? 00:39:33.700 --> 00:39:36.540 the it was 00:39:36.540 --> 00:39:39.300 something that left 00:39:39.940 --> 00:39:41.460 a 00:39:41.460 --> 00:39:43.460 burning substance and 00:39:43.460 --> 00:39:46.700 It meant the exhaustion 00:39:46.700 --> 00:39:49.420 when when 00:39:49.420 --> 00:39:51.220 phlogiston had 00:39:51.220 --> 00:39:55.940 Filled up the space you couldn't burn anything more in it 00:39:55.940 --> 00:39:58.340 and 00:39:58.340 --> 00:40:05.140 It made it very hard to understand chemical reactions, but then Priestley and 00:40:05.140 --> 00:40:07.780 I 00:40:07.780 --> 00:40:10.260 Guess Lavoisier was another one 00:40:10.260 --> 00:40:14.340 Two or three people around the same time were we're seeing 00:40:14.340 --> 00:40:18.620 That there was something 00:40:18.620 --> 00:40:28.100 Being consumed from the air in the process of burning rather than added to it and 00:40:28.100 --> 00:40:31.140 the 00:40:31.140 --> 00:40:32.620 when they 00:40:32.620 --> 00:40:38.980 started studying what was being consumed in the air as they saw that it generally made an 00:40:38.980 --> 00:40:42.020 acid form 00:40:42.020 --> 00:40:44.060 and so the 00:40:44.060 --> 00:40:47.980 I think was Priestley who named it the 00:40:47.980 --> 00:40:54.260 the substance that makes burning possible in the air he called the 00:40:54.260 --> 00:40:57.660 acid former or the oxygen 00:40:57.660 --> 00:41:01.620 Oxygen 00:41:02.260 --> 00:41:04.460 Root for acid or sour 00:41:04.460 --> 00:41:07.460 mm-hmm 00:41:07.460 --> 00:41:15.700 So so many acids were formed by oxygen that got its name as the source of acid 00:41:15.700 --> 00:41:18.700 and 00:41:18.700 --> 00:41:26.420 It isn't an absolute there are acids without oxygen and and that 00:41:26.420 --> 00:41:31.420 leads into the the whole issue of pH but 00:41:32.420 --> 00:41:39.500 Thinking of oxygen in relation to its ability to form acids 00:41:39.500 --> 00:41:48.180 That's a very important to integrate with your thinking of what a cell is doing 00:41:48.180 --> 00:41:51.220 and 00:41:51.220 --> 00:41:53.300 People tend to have 00:41:53.300 --> 00:41:58.300 Begun thinking of carbon dioxide is simply a waste product 00:41:59.100 --> 00:42:02.980 but if you think of the electronic 00:42:02.980 --> 00:42:06.660 Balance 00:42:06.660 --> 00:42:08.660 between oxidation and reduction 00:42:08.660 --> 00:42:11.460 holding the proteins and 00:42:11.460 --> 00:42:15.940 other things of the cell in a certain very specific 00:42:15.940 --> 00:42:18.940 state or confirmation 00:42:18.940 --> 00:42:23.780 Changing the pH is 00:42:23.780 --> 00:42:26.820 crucial and 00:42:26.820 --> 00:42:28.980 this partial 00:42:28.980 --> 00:42:30.980 oxidation that you get 00:42:30.980 --> 00:42:33.260 at a lower pH 00:42:33.260 --> 00:42:35.620 which 00:42:35.620 --> 00:42:39.500 governs the arrangement of the protein and other substances 00:42:39.500 --> 00:42:42.300 carbon dioxide 00:42:42.300 --> 00:42:44.300 turns out to be a 00:42:44.300 --> 00:42:47.300 universal 00:42:47.300 --> 00:42:52.740 Balancing factor or a adjuster of the 00:42:52.740 --> 00:42:56.060 acidic properties of the protein 00:42:56.860 --> 00:43:03.140 So the the acid formed by oxygen in this case carbon dioxide 00:43:03.140 --> 00:43:12.740 It's in itself it's an acid as defined by Gilbert Lewis 00:43:12.740 --> 00:43:17.140 and it doesn't have the protons so you 00:43:17.140 --> 00:43:19.380 you need 00:43:19.380 --> 00:43:22.620 talk about the pH really because it's 00:43:23.220 --> 00:43:28.460 It's a non protic acid just two oxygens in the carbon 00:43:28.460 --> 00:43:35.060 but this arrangement an oxygen doubly bonded to a carbon 00:43:35.060 --> 00:43:39.700 Creates that 00:43:39.700 --> 00:43:43.900 electron withdrawing property the intrinsic partial 00:43:43.900 --> 00:43:51.100 oxidizing property of that molecule which when it attaches to a protein it 00:43:51.900 --> 00:43:53.900 increases the acidity of the protein 00:43:53.900 --> 00:44:01.380 Making it slightly partially more oxidized more city and 00:44:01.380 --> 00:44:04.620 that changes its affinity for 00:44:04.620 --> 00:44:10.180 other things according to how negatively charged its groups are and 00:44:10.180 --> 00:44:14.580 This this is 00:44:14.580 --> 00:44:17.180 the kind of thinking that 00:44:17.180 --> 00:44:19.860 up to the 00:44:19.980 --> 00:44:21.980 the Gilbert Ling 00:44:21.980 --> 00:44:23.980 orientation 00:44:23.980 --> 00:44:31.900 Accounting for cells and their metabolism without the hypothetical membrane and its pumps 00:44:31.900 --> 00:44:34.860 the 00:44:34.860 --> 00:44:36.860 pH and the 00:44:36.860 --> 00:44:39.860 acid property of the protein system 00:44:39.860 --> 00:44:42.180 maintains by 00:44:42.180 --> 00:44:44.180 the carbon dioxide produced by 00:44:44.180 --> 00:44:47.020 oxidation 00:44:47.140 --> 00:44:50.220 This is the central thing in 00:44:50.220 --> 00:44:55.900 Explaining why cells can discriminate 00:44:55.900 --> 00:44:59.060 between 00:44:59.060 --> 00:45:01.060 sodium and potassium and 00:45:01.060 --> 00:45:06.380 calcium and magnesium and all of the discriminations that cells make 00:45:06.380 --> 00:45:10.180 You don't need a little magic pump 00:45:10.180 --> 00:45:13.020 moving things in and out 00:45:13.020 --> 00:45:15.020 that would 00:45:15.020 --> 00:45:17.180 Consume more energy than the cell has 00:45:17.180 --> 00:45:21.060 The energy of the cell is really being produced 00:45:21.060 --> 00:45:25.500 To form 00:45:25.500 --> 00:45:33.420 Carbon dioxide and the carbon dioxide is changing the and maintaining the properties 00:45:33.420 --> 00:45:37.060 Preventing excess 00:45:37.060 --> 00:45:40.340 Electron accumulation 00:45:40.340 --> 00:45:43.500 And 00:45:44.020 --> 00:45:48.740 It since it's a continuing streaming process you have 00:45:48.740 --> 00:45:53.540 oxygen streaming in and carbon dioxide streaming out and 00:45:53.540 --> 00:45:56.660 the carbon dioxide 00:45:56.660 --> 00:45:59.180 Reacting as an acid with water 00:45:59.180 --> 00:46:06.420 Shifts the the property of the the water atom 00:46:06.420 --> 00:46:12.420 So the the water joins with the carbon dioxide forming carbonic acid 00:46:12.860 --> 00:46:14.860 which ionizes 00:46:14.860 --> 00:46:20.380 You now have a negative charge on the carbon dioxide 00:46:20.380 --> 00:46:24.420 streaming out of the cell it takes 00:46:24.420 --> 00:46:28.460 Positive charges out with it 00:46:28.460 --> 00:46:31.780 otherwise the cell would 00:46:31.780 --> 00:46:36.300 quickly become highly electrically charged so the 00:46:36.300 --> 00:46:40.420 movement of oxygen in carbon dioxide out is 00:46:41.460 --> 00:46:43.460 taking out 00:46:43.460 --> 00:46:46.460 the sodium and calcium 00:46:46.460 --> 00:46:53.900 As a streaming continuous maintenance process 00:46:53.900 --> 00:46:57.380 Wow 00:46:57.380 --> 00:46:59.380 so this is the 00:46:59.380 --> 00:47:04.780 Most people have heard of the membrane theory of cells that they're basically bags 00:47:05.860 --> 00:47:13.860 Holding this cytoplasm in and this is in case you didn't get this. This is an alternative theory that it's actually being regulated 00:47:13.860 --> 00:47:22.060 By the products of the mitochondria is that right right so the mitochondria is producing the co2 00:47:22.060 --> 00:47:25.700 When it makes the ATP 00:47:25.700 --> 00:47:32.780 The energy we all use the ATP and so the co2 starts off as an electron acceptor, but then it becomes 00:47:32.780 --> 00:47:35.340 negatively charged and 00:47:35.500 --> 00:47:37.500 that bonds with the 00:47:37.500 --> 00:47:39.900 positive 00:47:39.900 --> 00:47:42.060 Metal ions the magnesium and calcium 00:47:42.060 --> 00:47:49.500 Yeah, it doesn't necessarily bond with them, but in leaving they tend to get dragged out, too 00:47:49.500 --> 00:47:52.260 I see and why is the co2 leaving? 00:47:52.260 --> 00:48:00.860 Just because it's being constantly formed inside and it just diffuses out down the gradient 00:48:00.860 --> 00:48:03.300 So that's like an osmotic pressure 00:48:03.900 --> 00:48:05.660 um 00:48:05.660 --> 00:48:07.660 No, yeah, well 00:48:07.660 --> 00:48:09.980 But the diffusion pressure 00:48:09.980 --> 00:48:12.380 It's it's going down the gradient 00:48:12.380 --> 00:48:15.260 like if you 00:48:15.260 --> 00:48:17.420 put alcohol 00:48:17.420 --> 00:48:19.860 against water 00:48:19.860 --> 00:48:26.780 Tend to mix the alcohol will move into the water and the water into the alcohol 00:48:26.780 --> 00:48:30.620 Until they're more or less even and 00:48:31.620 --> 00:48:35.740 When you have a high concentration of co2 in the cell 00:48:35.740 --> 00:48:39.020 at a certain point it starts 00:48:39.020 --> 00:48:46.780 Being more at ease outside of the cell I see so it's a diffusion process 00:48:46.780 --> 00:48:53.780 yeah, and that accounts for taking it out into the extracellular space and the blood and 00:48:53.780 --> 00:48:56.820 When it gets into the blood 00:48:56.820 --> 00:48:59.660 it having 00:48:59.940 --> 00:49:01.940 taken the 00:49:01.940 --> 00:49:06.820 Sodium and some other things with it 00:49:06.820 --> 00:49:10.820 It circulates to the lungs and 00:49:10.820 --> 00:49:13.900 Changes 00:49:13.900 --> 00:49:16.620 back to carbon dioxide, which is 00:49:16.620 --> 00:49:18.580 again 00:49:18.580 --> 00:49:24.500 Going down its gradient from a high concentration in your blood to a lower 00:49:24.900 --> 00:49:31.940 Concentration in the fresh air you breathe so the the carbon dioxide is leaving the blood and it leaves behind 00:49:31.940 --> 00:49:34.060 the 00:49:34.060 --> 00:49:36.700 Molecules or ions that it took out of the cells 00:49:36.700 --> 00:49:39.980 and so the 00:49:39.980 --> 00:49:47.460 Absence of the acidic carbon dioxide in the blood leaves the blood now with a higher pH 00:49:47.460 --> 00:49:50.580 because of the 00:49:50.580 --> 00:49:52.220 movement of 00:49:52.220 --> 00:49:55.140 Sodium and such out of the cell hmm 00:49:55.140 --> 00:49:58.580 I see 00:49:58.580 --> 00:50:04.860 So the normal situation is is for a healthy cell to be 00:50:04.860 --> 00:50:08.060 just faintly under 00:50:08.060 --> 00:50:10.300 neutrality 00:50:10.300 --> 00:50:11.940 and 00:50:11.940 --> 00:50:13.940 for the blood to be 00:50:13.940 --> 00:50:19.660 definitely over neutrality and like inside the cell 6.9 pH and 00:50:19.660 --> 00:50:22.180 in the blood 00:50:22.340 --> 00:50:24.340 7.4 roughly 00:50:24.340 --> 00:50:26.580 Okay 00:50:26.580 --> 00:50:33.380 7.4 I see so that's a little bit higher than the cell is low. Yeah 00:50:33.380 --> 00:50:36.820 Yeah, go on 00:50:36.820 --> 00:50:40.100 The 00:50:40.100 --> 00:50:43.580 Lot of people have 00:50:43.580 --> 00:50:48.620 Seen a disease as caused by a 00:50:50.060 --> 00:50:52.620 low pH or too much acidity and 00:50:52.620 --> 00:50:56.260 In the case of stress and 00:50:56.260 --> 00:50:59.340 Cancer a tumor will 00:50:59.340 --> 00:51:02.140 become very acidic 00:51:02.140 --> 00:51:07.020 so that traditional idea has as a basis that 00:51:07.020 --> 00:51:11.540 An infection or a tumor 00:51:11.540 --> 00:51:14.300 the inflammation 00:51:14.300 --> 00:51:18.460 produces high concentration of lactic acid and 00:51:18.820 --> 00:51:21.300 And a very low pH in that area 00:51:21.300 --> 00:51:24.260 which does have 00:51:24.260 --> 00:51:30.260 disruptive toxic effects on that area and so the body is 00:51:30.260 --> 00:51:34.220 Able generally to correct that and 00:51:34.220 --> 00:51:41.140 Reduce the inflammation and stop the production of lactic acid, but the 00:51:41.140 --> 00:51:46.980 When lactic acid is formed it 00:51:48.220 --> 00:51:52.860 If the conversion from pyruvic acid to lactic acid 00:51:52.860 --> 00:52:01.420 Is drawing an extra proton out of the NADH 00:52:01.420 --> 00:52:08.140 Catalyst that causes the conversion and 00:52:08.140 --> 00:52:16.780 In taking away this extra proton as as it leaves it 00:52:17.780 --> 00:52:20.780 In its formation it 00:52:20.780 --> 00:52:24.620 Raises the pH inside the cell 00:52:24.620 --> 00:52:30.420 so even though a tumor or an infection is 00:52:30.420 --> 00:52:34.260 Locally you see 00:52:34.260 --> 00:52:37.220 excess acid 00:52:37.220 --> 00:52:41.220 Hydro lactic acid inside the cell that's doing that 00:52:41.980 --> 00:52:45.780 It's the reverse process you get an increase in the pH 00:52:45.780 --> 00:52:48.420 inside the cell and 00:52:48.420 --> 00:52:53.740 So the cell which is stuck if it gets stuck in producing 00:52:53.740 --> 00:52:56.260 Lactic acid because it can't produce 00:52:56.260 --> 00:53:03.100 co2 and that means it also tends to get stuck at a higher pH and 00:53:03.100 --> 00:53:05.940 this higher pH 00:53:05.940 --> 00:53:07.980 Changes the whole system 00:53:07.980 --> 00:53:10.740 And 00:53:10.740 --> 00:53:15.900 That's that's where you tend to get a self replicating tumor 00:53:15.900 --> 00:53:23.260 Because the normal acidic conditions maintained by the co2 00:53:23.260 --> 00:53:27.180 Are lost I see 00:53:27.180 --> 00:53:30.620 Okay, that's that's 00:53:30.620 --> 00:53:35.020 Good to know and maybe you could explain for us. I don't think you have to go through the entire 00:53:35.020 --> 00:53:37.780 Cycle, but you're talking about 00:53:38.260 --> 00:53:42.300 Cellular respiration and I don't think people generally know that pyruvic 00:53:42.300 --> 00:53:46.580 when you're talking about that you're talking about the products or the process of 00:53:46.580 --> 00:53:52.860 Making the energy that we all use and could could you just give us a little cliff note version of that? 00:53:52.860 --> 00:53:55.820 yeah, the 00:53:55.820 --> 00:54:00.120 Looking at us in our environment. We're really sort of 00:54:00.120 --> 00:54:05.820 sandwiched between the sugar energy we get from plants and 00:54:06.700 --> 00:54:14.340 The carbon dioxide that we make as the final product of the energy from the sugar 00:54:14.340 --> 00:54:17.260 and the 00:54:17.260 --> 00:54:21.980 Series of 00:54:21.980 --> 00:54:25.180 Changes in the sugar molecule 00:54:25.180 --> 00:54:28.540 each 00:54:28.540 --> 00:54:31.860 Oxidation of that molecule 00:54:32.780 --> 00:54:39.100 Adds a little chemical energy to the cell that the cells can use to make proteins 00:54:39.100 --> 00:54:42.340 As it degrades the sugar it builds up 00:54:42.340 --> 00:54:46.260 amino acids and proteins and fats and 00:54:46.260 --> 00:54:51.220 When you're unable to 00:54:51.220 --> 00:54:57.980 Oxidize the sugar all the way down to carbon dioxide and 00:54:57.980 --> 00:55:01.220 produce 00:55:01.660 --> 00:55:08.900 Amylactic acids instead halfway you're losing the greatest part of the energy stored in the glucose molecule 00:55:08.900 --> 00:55:11.820 and that lack of energy 00:55:11.820 --> 00:55:15.300 Has its repercussions but 00:55:15.300 --> 00:55:18.140 when there's really a 00:55:18.140 --> 00:55:22.460 lack of oxygen to continue the 00:55:22.460 --> 00:55:26.160 oxidation that NADH which 00:55:27.060 --> 00:55:30.740 Allowed pyruvic acid to take this shortcut off 00:55:30.740 --> 00:55:34.180 into the semi toxic lactic acid 00:55:34.180 --> 00:55:41.820 That has to be renewed before you can even make another lactic acid 00:55:41.820 --> 00:55:44.580 So without oxygen 00:55:44.580 --> 00:55:48.500 You need some kind of oxidant 00:55:48.500 --> 00:55:51.180 to even continue 00:55:51.180 --> 00:55:55.820 producing that kind of low energy from sugar to 00:55:56.820 --> 00:56:00.620 Pyruvic and lactic acid and to do that cells 00:56:00.620 --> 00:56:03.740 can 00:56:03.740 --> 00:56:05.740 produce fat 00:56:05.740 --> 00:56:11.980 And get rid of their electrons by building them in the fat 00:56:11.980 --> 00:56:19.420 So building fat in a way is an alternative very bad one to 00:56:19.420 --> 00:56:23.260 Using up oxygen and making co2 00:56:24.900 --> 00:56:31.820 So interestingly cancers which get stuck in the 00:56:31.820 --> 00:56:38.940 Exclusive use of converting glucose or amino acids to 00:56:38.940 --> 00:56:45.660 Lactic acid as their energy supply. They also get stuck making 00:56:45.660 --> 00:56:47.980 fat 00:56:47.980 --> 00:56:50.500 That becomes their oxygen in effect 00:56:52.940 --> 00:56:55.460 And then when they 00:56:55.460 --> 00:56:59.260 Still have mitochondrial function 00:56:59.260 --> 00:57:01.940 the 00:57:01.940 --> 00:57:07.100 cell burns fat as it's energy source 00:57:07.100 --> 00:57:10.460 so it's a 00:57:10.460 --> 00:57:13.180 Really a deranged and crazy 00:57:13.180 --> 00:57:15.860 kind of metabolism to 00:57:15.860 --> 00:57:17.500 produce 00:57:17.500 --> 00:57:20.100 an irritant lactic acid 00:57:20.100 --> 00:57:22.580 to 00:57:22.580 --> 00:57:27.860 And to do that it has to make fat which is then used as fuel 00:57:27.860 --> 00:57:30.540 with with its own 00:57:30.540 --> 00:57:34.740 Consequences 00:57:34.740 --> 00:57:37.500 And is that that's called 00:57:37.500 --> 00:57:39.980 glycolysis 00:57:39.980 --> 00:57:44.860 Yeah, it's aerobic glycolysis when you make lactic acid 00:57:44.860 --> 00:57:47.620 in the presence of oxygen 00:57:47.620 --> 00:57:50.140 and 00:57:50.140 --> 00:57:51.900 ordinary 00:57:51.900 --> 00:57:53.380 anaerobic 00:57:53.380 --> 00:57:55.540 Glycolysis is what happens when you 00:57:55.540 --> 00:57:58.900 Exercise too hard 00:57:58.900 --> 00:58:02.180 You're you can build up lactic acid 00:58:02.180 --> 00:58:06.140 In getting out of breath 00:58:06.140 --> 00:58:09.500 The the blood lactate 00:58:09.500 --> 00:58:15.420 increases if you exercise faster than your breathing and 00:58:16.060 --> 00:58:24.060 That's normal. You can a little later consume and oxidize the lactic acid and that's okay 00:58:24.060 --> 00:58:27.300 when when you 00:58:27.300 --> 00:58:33.420 Start producing lactic acid even in the presence of oxygen as in the case of cancer 00:58:33.420 --> 00:58:36.060 or 00:58:36.060 --> 00:58:42.060 Extreme trauma or shock same thing happens something turns the the trigger 00:58:43.020 --> 00:58:47.660 So that even though oxygen is is present in shock 00:58:47.660 --> 00:58:50.020 you will 00:58:50.020 --> 00:58:53.660 Waste waste your sugar and make lactic acid. I 00:58:53.660 --> 00:59:00.260 See so oxygen is there and but it's not you're unable to use it 00:59:00.260 --> 00:59:04.580 Yeah, and the nervous system is 00:59:04.580 --> 00:59:10.940 In the case of shock at least the nervous system is involved in making that 00:59:11.660 --> 00:59:13.660 aerobic glycolysis and 00:59:13.660 --> 00:59:18.260 So there are quite a few people who have 00:59:18.260 --> 00:59:27.020 Suggested that the nervous system is involved in in the cancer transition doing the same thing that shock and trauma 00:59:27.020 --> 00:59:29.860 Can do acutely? 00:59:29.860 --> 00:59:31.460 hmm 00:59:31.460 --> 00:59:37.660 Wow, I have to take a short break here and say that you're listening to WM rw lp1 and 00:59:38.940 --> 00:59:45.100 We're streaming live at WM rw.org or 95 1 FM and you're listening to politics and science 00:59:45.100 --> 00:59:47.780 I'm John Barkas and the host and my guest today is 00:59:47.780 --> 00:59:54.500 Dr. Raymond Peat. He said has a PhD in biology and a speciality in physiology and 00:59:54.500 --> 00:59:57.340 we're talking around the subject of 00:59:57.340 --> 01:00:05.780 Oxidation and health and what role oxidation plays in maintaining that health 01:00:06.780 --> 01:00:08.780 There's 01:00:08.780 --> 01:00:12.140 More I want to ask you about the 01:00:12.140 --> 01:00:16.300 The not being able to 01:00:16.300 --> 01:00:20.460 use the oxygen that's present and 01:00:20.460 --> 01:00:26.460 Anaerobic it's anaerobic glycolysis, even though there's oxygen there 01:00:26.460 --> 01:00:30.300 And how aerobic oh 01:00:30.300 --> 01:00:34.980 and then it's called aerobic like hell is this I see and I 01:00:35.620 --> 01:00:40.460 How does the mitochondria make do with burning a fat? How is that even possible? 01:00:40.460 --> 01:00:43.500 um 01:00:43.500 --> 01:00:45.020 it's 01:00:45.020 --> 01:00:47.940 And what what are the problems with that? Oh 01:00:47.940 --> 01:00:58.340 It produces less carbon dioxide for example, I think that's the main problem 01:00:58.340 --> 01:01:03.140 The 01:01:04.780 --> 01:01:06.780 If you develop 01:01:06.780 --> 01:01:08.940 fat stores you get 01:01:08.940 --> 01:01:16.140 particles of fat accumulating in the cytoplasm and maybe in the nucleus that 01:01:16.140 --> 01:01:25.180 Probably have a disruptive effect when you're heavily shifted over to a fat economy 01:01:25.180 --> 01:01:29.620 I see if the 01:01:29.620 --> 01:01:33.600 The tumor makes saturated fat 01:01:34.460 --> 01:01:35.620 as 01:01:35.620 --> 01:01:36.820 its 01:01:36.820 --> 01:01:39.060 first product in in converting 01:01:39.060 --> 01:01:41.980 sugar to saturated fat 01:01:41.980 --> 01:01:45.220 But 01:01:45.220 --> 01:01:47.220 when it's shifting 01:01:47.220 --> 01:01:53.060 in in the presence of stress when it shifts to burning fat 01:01:53.060 --> 01:01:57.860 Usually that will go through your fat stores 01:01:59.500 --> 01:02:03.060 Burning up your your subcutaneous fat 01:02:03.060 --> 01:02:09.860 quickly, so when the person is very sick with cancer, for example, they get a 01:02:09.860 --> 01:02:13.020 gaunt initiated look as as their 01:02:13.020 --> 01:02:18.980 Superficial fat stores are are used up and at the same time 01:02:18.980 --> 01:02:25.620 They convert amino acids to energy 01:02:26.860 --> 01:02:29.100 Converting some of it to sugar and some to fat 01:02:29.100 --> 01:02:35.220 So it starts a wasting process but our stores 01:02:35.220 --> 01:02:43.740 the older person gets generally the higher the amount of polyunsaturated fat in their stores and 01:02:43.740 --> 01:02:50.420 When you're oxidizing polyunsaturated fats that produces more 01:02:50.420 --> 01:02:53.980 oxidative damage to the mitochondria 01:02:56.620 --> 01:02:58.620 So it tends to 01:02:58.620 --> 01:03:04.860 lower the oxidative a part of metabolism and and slow things down in general I 01:03:04.860 --> 01:03:09.860 See and then people end up feeling a lot less energy levels 01:03:09.860 --> 01:03:14.380 Generally get run down 01:03:14.380 --> 01:03:16.860 Yeah 01:03:16.860 --> 01:03:18.780 that happens 01:03:18.780 --> 01:03:21.660 in midlife to lots of people that 01:03:22.220 --> 01:03:27.660 It resembles the cancer metabolism, but it just shows up as fatigue 01:03:27.660 --> 01:03:31.820 low energy use in general 01:03:31.820 --> 01:03:35.220 some people or where 01:03:35.220 --> 01:03:41.980 Textbooks used to say that you would always lose weight if you ate less than 1700 calories per day 01:03:41.980 --> 01:03:49.620 Lots of people can maintain their weight on 700 calories a day 01:03:50.620 --> 01:03:52.620 And 01:03:52.620 --> 01:03:58.420 That requires turning off of the thyroid function to a great extent and 01:03:58.420 --> 01:04:02.540 So you're 01:04:02.540 --> 01:04:06.780 Being wasteful even though you're not using 01:04:06.780 --> 01:04:10.500 Very much energy at all what you are using 01:04:10.500 --> 01:04:14.220 Tends to be poorly used and destructive 01:04:14.220 --> 01:04:17.380 so you tend to 01:04:18.020 --> 01:04:20.020 reduce your 01:04:20.020 --> 01:04:22.620 Connective tissue and muscle and and 01:04:22.620 --> 01:04:25.780 digestive system and so on 01:04:25.780 --> 01:04:27.660 rather than 01:04:27.660 --> 01:04:31.180 Just living on on what you're eating or stored fat 01:04:31.180 --> 01:04:35.580 Well, so basically basically you're hibernating 01:04:35.580 --> 01:04:39.100 You got fuzzy I couldn't tell 01:04:39.100 --> 01:04:45.100 It's very girdly, okay 01:04:45.100 --> 01:04:50.140 I'm gonna call you back. You back. We'll resume resume. Okay. Okay. Okay. Bye 01:04:50.140 --> 01:04:54.420 Hello you're on the air, can you hear me? 01:04:54.420 --> 01:04:57.580 Yeah, you're still a little still gargling 01:04:57.580 --> 01:05:03.900 Not as bad as it was. Okay, we're you're coming through fine. So if you if you can 01:05:03.900 --> 01:05:07.480 Put up with it. We can we're good to go. Okay 01:05:11.620 --> 01:05:17.660 So our fats always the part of the process of respiration oxidizing fats or is that only when you're ill 01:05:17.660 --> 01:05:23.780 Yeah, it's only under stress generally and 01:05:23.780 --> 01:05:28.500 Starvation. Mm-hmm or or diabetes or 01:05:28.500 --> 01:05:30.660 or a 01:05:30.660 --> 01:05:34.780 High high level of stress. I see a lot of people are on those 01:05:34.780 --> 01:05:36.820 ketosis 01:05:36.820 --> 01:05:38.820 diets where they don't eat any 01:05:38.820 --> 01:05:40.860 carbohydrates and 01:05:40.860 --> 01:05:42.860 Does that cause you to burn fats? 01:05:42.860 --> 01:05:46.380 And protein and protein, right? 01:05:46.380 --> 01:05:53.820 Yeah, your brain and some other tissues the intestine and red blood cells and 01:05:53.820 --> 01:05:56.860 various 01:05:56.860 --> 01:05:58.060 little 01:05:58.060 --> 01:06:02.300 little areas, but especially the brain and have an absolute 01:06:02.300 --> 01:06:06.380 requirement for some sugar some glucose and 01:06:07.540 --> 01:06:09.740 They all get it by breaking down 01:06:09.740 --> 01:06:15.420 Amino acids and they get that from eating your tissues if you aren't 01:06:15.420 --> 01:06:18.260 eating 01:06:18.260 --> 01:06:19.620 enough 01:06:19.620 --> 01:06:22.300 amino acids, but if you 01:06:22.300 --> 01:06:26.060 are eating amino acids as your 01:06:26.060 --> 01:06:31.380 Energy source fats and amino acids 01:06:31.380 --> 01:06:34.700 you 01:06:34.700 --> 01:06:37.660 Turn on the machinery for turning 01:06:37.660 --> 01:06:42.580 Amino acids into glucose and fat and 01:06:42.580 --> 01:06:45.700 running that 01:06:45.700 --> 01:06:51.380 machinery involves turning on stress hormones a whole range of 01:06:51.380 --> 01:06:53.980 hormones adjust to it and 01:06:53.980 --> 01:06:56.100 I 01:06:56.100 --> 01:06:59.460 Think those have chronic harmful effects. I 01:07:01.100 --> 01:07:04.900 See so I know when people do it they're usually in a very controlled 01:07:04.900 --> 01:07:13.340 Setting they go in for regular checkups and I think that I don't actually know but I think they take blood and urine samples and 01:07:13.340 --> 01:07:17.300 You know, they're trying to make sure you're not actually endangering yourself 01:07:17.300 --> 01:07:23.420 Most of the proteins that are are being eaten under those systems 01:07:23.420 --> 01:07:27.100 most of them are too high in phosphate and 01:07:29.180 --> 01:07:31.780 Usually too high in in this ionine 01:07:31.780 --> 01:07:34.860 cysteine and tryptophan and 01:07:34.860 --> 01:07:40.420 cysteine is an excited toxic amino acid and 01:07:40.420 --> 01:07:43.780 Methionine 01:07:43.780 --> 01:07:49.820 is involved in in stress and aging when in proportion to its excess so that 01:07:49.820 --> 01:07:55.140 one of the most effective life extending 01:07:55.900 --> 01:08:01.660 Diets is simply to reduce the amount of methionine in the diet drastically 01:08:01.660 --> 01:08:07.900 So the sulfur amino acids and tryptophan are 01:08:07.900 --> 01:08:11.260 stress and aging promoters 01:08:11.260 --> 01:08:15.660 Especially excited toxic damage to the nerves 01:08:15.660 --> 01:08:18.980 And 01:08:18.980 --> 01:08:23.540 And the high phosphate for most of the popular proteins 01:08:25.100 --> 01:08:27.100 The high phosphate is 01:08:27.100 --> 01:08:29.940 has a lot of 01:08:29.940 --> 01:08:32.100 excitatory harmful effects 01:08:32.100 --> 01:08:34.580 the 01:08:34.580 --> 01:08:35.980 cloth 01:08:35.980 --> 01:08:41.260 Oh gene and protein that is deficient in 01:08:41.260 --> 01:08:47.420 Animals that have a very quick aging process 01:08:47.420 --> 01:08:50.620 that's 01:08:50.620 --> 01:08:53.380 Largely a phosphate handling 01:08:54.300 --> 01:08:56.300 protein and 01:08:56.300 --> 01:09:00.860 The rapid aging produced by lacking that protein and gene 01:09:00.860 --> 01:09:04.140 is 01:09:04.140 --> 01:09:06.980 involves accumulating excess phosphate 01:09:06.980 --> 01:09:12.100 And that in phosphate you get from eating meat primarily or 01:09:12.100 --> 01:09:15.060 meat is 01:09:15.060 --> 01:09:18.500 one of the highest ratios of phosphate to 01:09:18.500 --> 01:09:21.100 the other minerals 01:09:21.100 --> 01:09:24.700 But several of the very high quality proteins 01:09:24.700 --> 01:09:30.620 Even mushrooms have a pretty high ratio of phosphate to calcium 01:09:30.620 --> 01:09:33.180 milk is 01:09:33.180 --> 01:09:38.540 Milk and cheese are about half and half which is probably safe, but 01:09:38.540 --> 01:09:41.260 fruits and leaves 01:09:41.260 --> 01:09:49.460 leafy green vegetables have a very safe low very low phosphate content relative to 01:09:50.100 --> 01:09:56.380 Calcium and magnesium and potassium. I see so fruits and vegetables are 01:09:56.380 --> 01:10:01.820 The best but you're not getting much protein in that case so 01:10:01.820 --> 01:10:05.180 You need some milk and cheese, too 01:10:05.180 --> 01:10:11.300 Yeah, and probably a fairly low protein diet is 01:10:11.300 --> 01:10:18.780 Very good for the health but in the sense of living a long time but 01:10:19.780 --> 01:10:21.780 For 01:10:21.780 --> 01:10:23.620 Maintaining 01:10:23.620 --> 01:10:25.540 tissue renewal 01:10:25.540 --> 01:10:29.180 You can't go below a certain amount of tryptophan 01:10:29.180 --> 01:10:31.700 cysteine and thiamine those are 01:10:31.700 --> 01:10:34.020 rapid turnover 01:10:34.020 --> 01:10:36.020 proteins 01:10:36.020 --> 01:10:38.660 Okay 01:10:38.660 --> 01:10:41.500 You know I think Ray I'm going to turn to some of the questions 01:10:41.500 --> 01:10:45.500 I receive from people in preparation for the show because I know if I wait 01:10:45.900 --> 01:10:50.580 We're gonna be short on time, and I want to make sure you have time to answer them 01:10:50.580 --> 01:10:56.980 Last week we talked about or you mentioned Luca Turin and his research on 01:10:56.980 --> 01:11:02.580 I think it was odors and the electrical nature of odors he had 01:11:02.580 --> 01:11:05.300 maybe you could 01:11:05.300 --> 01:11:08.340 when you get to answering this you could go over that a little bit, but 01:11:08.340 --> 01:11:14.340 Somebody wanted to know what your feelings are about multiple chemical sensitivity 01:11:15.260 --> 01:11:16.700 and that's 01:11:16.700 --> 01:11:21.940 pretty common these days a lot of people can be made very ill by a perfume or the smell of bounce and 01:11:21.940 --> 01:11:26.940 What do you think of is going on and does that relate to Luca Turin's work? 01:11:26.940 --> 01:11:30.020 yeah, I think it does and 01:11:30.020 --> 01:11:33.740 See he was 01:11:33.740 --> 01:11:36.860 Talking specifically about 01:11:36.860 --> 01:11:40.220 Smell and and 01:11:40.220 --> 01:11:44.860 psychoactive like antidepressant chemicals and 01:11:45.860 --> 01:11:48.620 there is when you look at the 01:11:48.620 --> 01:11:51.540 what's in common between 01:11:51.540 --> 01:11:54.980 Smelling and 01:11:54.980 --> 01:12:00.620 Having the antidepressant effect of some chemicals 01:12:00.620 --> 01:12:03.500 what's in common is 01:12:03.500 --> 01:12:10.020 the resonance state or the tuning of the molecule to the 01:12:10.020 --> 01:12:13.900 Oxidation state 01:12:14.900 --> 01:12:16.900 Which is 01:12:16.900 --> 01:12:19.260 in this context of 01:12:19.260 --> 01:12:22.580 partially oxidized proteins in a 01:12:22.580 --> 01:12:25.740 coherent cooperative system 01:12:25.740 --> 01:12:34.100 The whole system has to be tuned to a certain level of reduction and oxidation and 01:12:34.100 --> 01:12:42.540 The the addition of a chemical whether it's an antidepressant or a perfume molecule 01:12:42.700 --> 01:12:44.700 and 01:12:44.700 --> 01:12:47.740 Passes along the conductive 01:12:47.740 --> 01:12:52.460 Pathways of the nervous system and 01:12:52.460 --> 01:12:59.860 Cells all through the body are are involved in 01:12:59.860 --> 01:13:07.580 The delicate nerve balances the vegetative or autonomic nervous system 01:13:07.580 --> 01:13:12.140 Regulates the state of inflammation 01:13:12.220 --> 01:13:14.220 of the tissues for example 01:13:14.220 --> 01:13:17.180 There are lots of 01:13:17.180 --> 01:13:18.700 cells 01:13:18.700 --> 01:13:20.700 closely associated with 01:13:20.700 --> 01:13:22.940 fibers of the nervous system 01:13:22.940 --> 01:13:28.780 Cells called mast cells for example that can regulate 01:13:28.780 --> 01:13:31.900 inflammation all through the body 01:13:31.900 --> 01:13:35.100 in the brain as well as 01:13:35.100 --> 01:13:40.060 all the other tissues and and these are are connected and 01:13:41.020 --> 01:13:47.460 Balanced with with the nervous system. So a slight shift in your autonomic nervous system 01:13:47.460 --> 01:13:51.340 Can 01:13:51.340 --> 01:13:55.460 Globally change the degree of inflammation all through your body 01:13:55.460 --> 01:14:00.980 Increasing the amount of histamine and serotonin and 01:14:00.980 --> 01:14:05.340 the various products of the mast cells 01:14:05.340 --> 01:14:08.660 this is 01:14:09.260 --> 01:14:15.220 when a person is under stress chronically these inflammatory things tend to rise and 01:14:15.220 --> 01:14:19.700 When you increase your 01:14:19.700 --> 01:14:22.540 intensity of 01:14:22.540 --> 01:14:25.500 mitochondrial respiration and your level of carbon dioxide 01:14:25.500 --> 01:14:28.380 that 01:14:28.380 --> 01:14:31.100 Stabilizes the system backs away from that excess 01:14:31.100 --> 01:14:33.860 inflammatory 01:14:33.860 --> 01:14:35.860 reductive impulse but 01:14:35.860 --> 01:14:38.500 When you're right on the edge 01:14:38.940 --> 01:14:40.940 Just balanced 01:14:40.940 --> 01:14:43.020 not intense enough 01:14:43.020 --> 01:14:46.540 oxidation going on then a 01:14:46.540 --> 01:14:50.260 perfume molecule or a 01:14:50.260 --> 01:14:55.260 Psychoactive chemical or a food molecule can 01:14:55.260 --> 01:14:59.420 Send impulses through your system shifting you 01:14:59.420 --> 01:15:02.620 away from the 01:15:02.620 --> 01:15:06.020 oxidative excitatory processes towards the 01:15:07.380 --> 01:15:10.700 Side of your nervous system that becomes dominant in shock 01:15:10.700 --> 01:15:15.820 So I think the the chronic fatigue and 01:15:15.820 --> 01:15:20.820 chemical sensitivity inflammatory states 01:15:20.820 --> 01:15:24.420 Are 01:15:24.420 --> 01:15:29.180 In effect a variation on the physiology of shock 01:15:29.180 --> 01:15:31.700 Hmm, that's really fascinating 01:15:31.700 --> 01:15:38.100 I mean, it's amazing that somebody can actually wear a product because they like the smell but that same product 01:15:38.100 --> 01:15:41.780 The smell of which can make somebody else deadly ill 01:15:41.780 --> 01:15:45.140 um, yeah, I think it's a 01:15:45.140 --> 01:15:50.780 Depends on the way you're nervous and chemical system is is tuned up 01:15:50.780 --> 01:15:57.460 I mean everything oxidation and reduction is involved in and all of our processes that are 01:15:57.460 --> 01:16:00.980 Chemical. Yeah 01:16:01.220 --> 01:16:03.220 lactic acid 01:16:03.220 --> 01:16:09.300 Is a reductant as well as a product of of being reduced 01:16:09.300 --> 01:16:16.460 And turning it into lactic acid from pyruvic acid 01:16:16.460 --> 01:16:20.220 Involves an electronic 01:16:20.220 --> 01:16:24.060 addition or reduction but it 01:16:24.060 --> 01:16:27.060 then when it goes to a 01:16:27.060 --> 01:16:29.620 balanced or healthy healthy cell 01:16:30.060 --> 01:16:33.300 It shifts the balance towards reduction 01:16:33.300 --> 01:16:39.900 And if you have oxygen in that cell, it's okay. The electrons will be consumed 01:16:39.900 --> 01:16:41.940 but 01:16:41.940 --> 01:16:47.140 Lactic acid itself has this potential for shifting the balance for example in 01:16:47.140 --> 01:16:50.300 the mast cells that are 01:16:50.300 --> 01:16:53.060 signals for more inflammation 01:16:53.060 --> 01:16:57.500 Too much lactic acid will activate their 01:16:58.780 --> 01:17:00.780 releases and 01:17:00.780 --> 01:17:03.300 so systemically 01:17:03.300 --> 01:17:06.540 letting too much lactic acid circulate is 01:17:06.540 --> 01:17:09.700 adding to the 01:17:09.700 --> 01:17:12.180 The inflammatory state 01:17:12.180 --> 01:17:16.300 And I know you've told me before people might be interested in this that 01:17:16.300 --> 01:17:20.020 you're not very fond of yogurt because of the 01:17:20.020 --> 01:17:23.060 lactic acid so you can actually 01:17:24.060 --> 01:17:31.620 Absorb lactic acid from your food directly. I mean, yeah, there are some kinds of yogurt that have very little 01:17:31.620 --> 01:17:33.540 lactic acid 01:17:33.540 --> 01:17:35.020 You can 01:17:35.020 --> 01:17:36.780 thicken the milk 01:17:36.780 --> 01:17:38.060 enzymically 01:17:38.060 --> 01:17:39.460 rather than 01:17:39.460 --> 01:17:43.020 With a lot of acid and those very mild yogurts 01:17:43.020 --> 01:17:45.700 aren't 01:17:45.700 --> 01:17:49.100 Especially harmful, but if they're very sour with lactic acid 01:17:49.100 --> 01:17:52.020 and if your liver is 01:17:52.500 --> 01:17:55.740 On edge not enough thyroid function 01:17:55.740 --> 01:17:57.780 then 01:17:57.780 --> 01:18:01.940 That slight shift in towards the reduction side 01:18:01.940 --> 01:18:05.540 Can have systemic effects and can bring on 01:18:05.540 --> 01:18:09.500 allergic reactions migraine headaches and such and 01:18:09.500 --> 01:18:15.100 So just talking specifically about yogurt if you we have a local yogurt 01:18:15.100 --> 01:18:19.020 Maker around here and I find if you buy it immediately 01:18:19.580 --> 01:18:24.780 You know as soon as it comes out, there's hardly no apparent lactic acid in it 01:18:24.780 --> 01:18:27.380 But the longer it sits the more the acids 01:18:27.380 --> 01:18:30.180 separates from the actual 01:18:30.180 --> 01:18:35.180 Milk product so I'm wondering is that acid 01:18:35.180 --> 01:18:39.780 Forming as it goes or is it always in there and you just shouldn't eat it period? 01:18:39.780 --> 01:18:41.860 No, the 01:18:41.860 --> 01:18:43.860 Bacteria are making it. Okay 01:18:43.860 --> 01:18:47.660 So a young a young yogurt would be fine 01:18:48.620 --> 01:18:50.620 Yeah, I think so. Okay 01:18:50.620 --> 01:18:56.820 Yeah, because that you can also strain your yogurt which is the same as buying Greek yogurt 01:18:56.820 --> 01:19:01.260 And that gets rid of it and basically makes a thicker or cheesier 01:19:01.260 --> 01:19:04.820 Thank you product. Yeah, that's the 01:19:04.820 --> 01:19:07.660 idea of cottage cheese 01:19:07.660 --> 01:19:10.580 They drain away 01:19:10.580 --> 01:19:14.540 most of the fluid the way 01:19:15.740 --> 01:19:21.100 And that takes away the almost all of the lactic acid for most cheeses 01:19:21.100 --> 01:19:28.460 Okay. Well, that's good to know that fresh yogurt is okay. I guess got a question coming in on the same subject 01:19:28.460 --> 01:19:30.460 We were talking about a second ago 01:19:30.460 --> 01:19:34.580 From Duncan. I bought a perfume base from a chemical company some years ago 01:19:34.580 --> 01:19:41.380 And it was so toxic that UPS was afraid to deliver it. I had to go pick it up myself on 01:19:41.380 --> 01:19:44.620 the MSDS toxicity scale 01:19:45.620 --> 01:19:48.420 Which goes from 0 to 4 this was a 6 01:19:48.420 --> 01:19:52.140 Yep, two points over the max for chemical toxicity 01:19:52.140 --> 01:19:58.860 Perfumes are very poisonous. He concludes. What's the MSDS? Is that the manufacturers? 01:19:58.860 --> 01:20:07.080 Safety data sheet. Thank you. Yes. All right, and he also asked you contribute to Wikipedia 01:20:07.080 --> 01:20:11.820 No, okay, and I'll go ahead 01:20:12.540 --> 01:20:14.540 someone has asked me to 01:20:14.540 --> 01:20:18.620 Comment on the 01:20:18.620 --> 01:20:21.100 association induction hypothesis 01:20:21.100 --> 01:20:24.740 Article a very good long article 01:20:24.740 --> 01:20:29.740 Describing Gilbert things theory a lot of people are jumping on it 01:20:29.740 --> 01:20:32.580 Saying that it should be 01:20:32.580 --> 01:20:36.060 Eliminated from Wikipedia because it's wrong 01:20:37.340 --> 01:20:42.140 Wow, well, that's surprising. I wonder if I've Gerald Pollack who also basically 01:20:42.140 --> 01:20:48.700 Derived a lot of his work from Gilbert Lange and says so I wonder if he might be there defending him 01:20:48.700 --> 01:20:53.260 Yeah, I I don't know how you get involved. I 01:20:53.260 --> 01:20:56.300 When I find out I think I'll 01:20:56.300 --> 01:21:00.180 Say keep it, please. Yeah, okay 01:21:00.180 --> 01:21:02.700 That would be good. Um 01:21:02.900 --> 01:21:08.860 Let's see, and I have some more questions here. I should I'm gonna find them so we get to them before the show is over 01:21:08.860 --> 01:21:11.060 This is from Paul 01:21:11.060 --> 01:21:15.660 He says I am a 34 year old male and since about eight months 01:21:15.660 --> 01:21:21.820 Type one diabetic. I believe I got diabetes after x-rays from my dentist 01:21:21.820 --> 01:21:28.540 I'm curious if you think that's possible. I take daily insulin and follow a pro metabolic diet. I 01:21:29.260 --> 01:21:33.940 supplement aspirin vitamin a vitamin e vitamin K b1 b3 glycine 01:21:33.940 --> 01:21:36.460 pregnenolone magnesium glycinate 01:21:36.460 --> 01:21:44.340 I am still in a so-called honeymoon phase and I would very much like to prolong this phase or even get off all insulin 01:21:44.340 --> 01:21:52.140 Do you have any tips or supplements? I might add to my regimen and he says thank you from the bottom of his heart 01:21:55.100 --> 01:22:00.580 Before I was born my father had extreme diabetes went down to 01:22:00.580 --> 01:22:04.140 Something like 90 pounds or less 01:22:04.140 --> 01:22:06.860 couldn't 01:22:06.860 --> 01:22:08.860 assimilate any kind of food 01:22:08.860 --> 01:22:11.860 even pure protein 01:22:11.860 --> 01:22:19.900 Raised his urine glucose tremendously and looking at old 01:22:19.900 --> 01:22:23.940 Naturopathic remedies 01:22:24.420 --> 01:22:28.700 He started eating as his only food 01:22:28.700 --> 01:22:34.060 Brewers yeast gator, I guess two cups a day at first and 01:22:34.060 --> 01:22:37.180 immediately stopped producing 01:22:37.180 --> 01:22:39.300 so much 01:22:39.300 --> 01:22:44.460 Glucose in his urine and in a few months was completely well 01:22:44.460 --> 01:22:49.740 Every maybe five years or so after that he would 01:22:50.460 --> 01:22:56.000 Eat some extra brewers yeast, but never had any symptom of 01:22:56.000 --> 01:22:58.940 diabetes after that and 01:22:58.940 --> 01:23:02.980 I think part of that effect is the 01:23:02.980 --> 01:23:06.300 the hormones in the yeast 01:23:06.300 --> 01:23:08.540 which 01:23:08.540 --> 01:23:10.540 stimulate 01:23:10.540 --> 01:23:16.660 Regeneration and high potassium content which has an insulin like action 01:23:18.260 --> 01:23:20.340 And the high B vitamins 01:23:20.340 --> 01:23:24.500 But 01:23:24.500 --> 01:23:28.420 having enough glucose so that you don't 01:23:28.420 --> 01:23:31.620 draw any 01:23:31.620 --> 01:23:36.860 Polyunsaturated fats out of storage. Those are very toxic to the 01:23:36.860 --> 01:23:42.740 The pen the insulin producing cells in the pancreas 01:23:42.740 --> 01:23:47.500 They are 01:23:47.500 --> 01:23:51.780 Normally, they're constantly turning over the beta cells are being renewed 01:23:51.780 --> 01:23:57.140 constantly and in a diabetic they're being renewed but they die quickly and 01:23:57.140 --> 01:24:03.940 Sugar is a factor that will prolong their lifespan 01:24:03.940 --> 01:24:10.380 It doesn't need anything to stimulate renewal just to prevent them being killed 01:24:10.380 --> 01:24:14.900 primarily by the polyunsaturated fats and the 01:24:16.460 --> 01:24:18.460 Nitric oxide is 01:24:18.460 --> 01:24:21.620 Soon after 01:24:21.620 --> 01:24:28.620 It was discovered that the body produces its own nitric oxide in the early 90s many 01:24:28.620 --> 01:24:33.940 articles came out demonstrating that nitric oxide is specifically 01:24:33.940 --> 01:24:37.180 what kills the beta cells and 01:24:37.180 --> 01:24:40.260 so you definitely don't want to 01:24:40.260 --> 01:24:43.460 Do anything that? 01:24:43.540 --> 01:24:48.980 Would increase your nitric oxide production. What kind of activity does that well? 01:24:48.980 --> 01:24:52.100 supplementing 01:24:52.100 --> 01:24:54.300 Arginine or foods high in arginine 01:24:54.300 --> 01:24:57.180 Wouldn't probably be desirable 01:24:57.180 --> 01:25:00.340 okay, and 01:25:00.340 --> 01:25:08.060 I think the the effects of aspirin and the B vitamins and the vitamin E 01:25:08.060 --> 01:25:11.780 Pregnenol and then progesterone and 01:25:12.660 --> 01:25:14.660 DHEA 01:25:14.660 --> 01:25:16.900 Around 01:25:16.900 --> 01:25:20.340 1985 I think it was someone 01:25:20.340 --> 01:25:22.900 gave rabbits 01:25:22.900 --> 01:25:29.660 diabetes with a chemical toxin and then gave them a supplement of DHEA and 01:25:29.660 --> 01:25:35.220 That was the only difference the ones that got the DHEA 01:25:35.220 --> 01:25:41.120 Regenerated healthy insulin producing pancreases 01:25:41.160 --> 01:25:43.160 Hmm 01:25:43.160 --> 01:25:48.960 And that has to be taken in small amounts. Are you converted to estrogen? Is that right? 01:25:48.960 --> 01:25:54.400 Yeah, 10 to 15 milligrams is probably a safe amount 01:25:54.400 --> 01:26:03.760 All right, and and one of the things that I think everybody will be surprised by is that you're actually advocating 01:26:03.760 --> 01:26:06.600 taking sugar or glucose 01:26:08.280 --> 01:26:13.840 Which is a couple of articles on my website I give some of the history of that 01:26:13.840 --> 01:26:16.480 in 01:26:16.480 --> 01:26:20.480 The late 19th century a couple of doctors 01:26:20.480 --> 01:26:23.400 described cases that they cured 01:26:23.400 --> 01:26:26.480 from 01:26:26.480 --> 01:26:30.800 really advanced terminal diabetes people losing 01:26:30.800 --> 01:26:33.280 weight 01:26:33.280 --> 01:26:35.120 terrific rate 01:26:35.120 --> 01:26:36.960 they added 01:26:36.960 --> 01:26:43.520 Something like 12 ounces per day of sugar to an otherwise good diet 01:26:43.520 --> 01:26:48.200 regular high protein and vegetables and 01:26:48.200 --> 01:26:54.520 Milk and so on. Hmm, but just by adding 12 ounces of 01:26:54.520 --> 01:26:57.720 sugar to that diet 01:26:57.720 --> 01:27:01.240 In just a few weeks people came back from near death 01:27:01.360 --> 01:27:07.640 Hmm and I guess their logic was since they were urinating out so much of their bodily sugar 01:27:07.640 --> 01:27:11.240 They figured maybe they were short on sugar. Yeah 01:27:11.240 --> 01:27:14.520 exactly, they their reasoning at first was 01:27:14.520 --> 01:27:19.160 They're dying so fast. They're putting out 01:27:19.160 --> 01:27:24.040 The equivalent of a pound of tissue 01:27:24.040 --> 01:27:27.560 Converted to sugar every day 01:27:27.560 --> 01:27:29.000 and 01:27:29.000 --> 01:27:35.880 Just to slow down their starvation process. They said them and and they crave sugar. Why not let them 01:27:35.880 --> 01:27:38.440 eat 01:27:38.440 --> 01:27:40.440 what they crave and 01:27:40.440 --> 01:27:43.920 maybe slow down their death, but instead they 01:27:43.920 --> 01:27:48.280 Stopped wasting away and came back. Hmm 01:27:48.280 --> 01:27:56.840 And I want to go back a little bit to because I think I did the person who asked the 01:27:57.480 --> 01:28:04.080 Multiple chemical sensitivity question a little short shrift and that I never asked you. What can somebody do? 01:28:04.080 --> 01:28:08.120 if if they're suffering from multiple chemical sensitivity 01:28:08.120 --> 01:28:11.000 I'm 01:28:11.000 --> 01:28:17.480 supplementing thyroid is the usual thing, but sometimes they're very low in cholesterol and 01:28:17.480 --> 01:28:21.120 since thyroid works partly through 01:28:21.120 --> 01:28:25.040 Converting cholesterol to 01:28:25.880 --> 01:28:29.520 Hormones like progesterone DHA and pregnenolone 01:28:29.520 --> 01:28:36.920 If your cholesterol is too low thyroid alone doesn't necessarily do it so 01:28:36.920 --> 01:28:46.720 Supplementing one or more of those will very quickly often relieve the 01:28:46.720 --> 01:28:50.320 Exaggerated sensitivity. Hmm 01:28:50.320 --> 01:28:52.880 Okay 01:28:52.880 --> 01:28:56.960 And it sounds like you said that the the rabbits were given 01:28:56.960 --> 01:29:00.160 diabetes just by being poisoned 01:29:00.160 --> 01:29:06.240 With a toxin and it sounds like that's happened. A lot of our diseases are actually 01:29:06.240 --> 01:29:09.040 environmentally caused it's 01:29:09.040 --> 01:29:11.360 You know, I know 01:29:11.360 --> 01:29:16.800 they say a lot of people have predispositions to cancer and diabetes and stuff like that, but I 01:29:16.800 --> 01:29:20.460 personally suspect a lot of it is just environmentally from the 01:29:21.240 --> 01:29:23.240 from the pollution that's 01:29:23.240 --> 01:29:25.480 inevitable in our industrial society 01:29:25.480 --> 01:29:28.480 you know when I was starting on my 01:29:28.480 --> 01:29:31.280 dissertation project I 01:29:31.280 --> 01:29:33.360 wondered what 01:29:33.360 --> 01:29:35.360 What the factors were that? 01:29:35.360 --> 01:29:37.880 slowed down 01:29:37.880 --> 01:29:40.640 oxidative processes in aging and 01:29:40.640 --> 01:29:48.280 As I looked around at the possibilities, I saw that the same type of deterioration 01:29:48.280 --> 01:29:51.120 the same 01:29:51.120 --> 01:29:53.040 biochemical 01:29:53.040 --> 01:29:56.440 patterns of interference with mitochondrial 01:29:56.440 --> 01:30:01.860 Respiration were produced by a great variety of stresses 01:30:01.860 --> 01:30:06.200 radiation ionizing radiation or 01:30:06.200 --> 01:30:10.040 even ultraviolet to excess 01:30:10.040 --> 01:30:18.080 Had an effect similar to all of the estrogens and the 01:30:19.200 --> 01:30:21.200 aromatic hydrocarbon 01:30:21.200 --> 01:30:25.040 carcinogens and hydrocarbons that produce 01:30:25.040 --> 01:30:28.360 excitation and inflammation 01:30:28.360 --> 01:30:31.000 and 01:30:31.000 --> 01:30:33.480 Polyunsaturated fatty acids 01:30:33.480 --> 01:30:37.400 produce the same the same pattern of 01:30:37.400 --> 01:30:40.760 deterioration and the vitamin E 01:30:40.760 --> 01:30:44.080 supplement was found to 01:30:44.080 --> 01:30:47.840 Stop the characteristic damage. They were seeing in 01:30:48.880 --> 01:30:55.080 lab rats and industrial animals for my feeding them too much unsaturated fat and 01:30:55.080 --> 01:30:57.960 my thesis advisor 01:30:57.960 --> 01:31:00.680 found that 01:31:00.680 --> 01:31:02.640 The 01:31:02.640 --> 01:31:04.640 effects of too much estrogen 01:31:04.640 --> 01:31:09.800 were corrected by a very large vitamin E supplement and 01:31:09.800 --> 01:31:16.960 Others were finding that vitamin E protects even against radiation and sunburn 01:31:17.960 --> 01:31:19.560 and 01:31:19.560 --> 01:31:21.560 so some of the 01:31:21.560 --> 01:31:24.800 processes like the breakdown of 01:31:24.800 --> 01:31:27.880 polyunsaturated fats are 01:31:27.880 --> 01:31:35.480 Increasing our susceptibility to damage from all of those stressors radiation estrogen 01:31:35.480 --> 01:31:42.720 Toxic heavy metals and so on. Mm-hmm and Ray is referring to the the liquid oils that 01:31:42.720 --> 01:31:46.480 Everywhere in our 01:31:46.480 --> 01:31:49.440 food supply the canola oil I 01:31:49.440 --> 01:31:53.100 Think you think olive oils not too bad and butter is good 01:31:53.100 --> 01:31:57.900 But all the vegetable oils except for coconut are not a good idea 01:31:57.900 --> 01:32:02.880 yeah, olive oil has only you know, eight or ten percent of the 01:32:02.880 --> 01:32:06.560 Unstable polyunsaturated 01:32:06.560 --> 01:32:14.160 butter and coconut oil have two or maybe three percent of the unstable ones 01:32:15.760 --> 01:32:17.320 I've 01:32:17.320 --> 01:32:19.320 recently finally 01:32:19.320 --> 01:32:21.800 Shifted 01:32:21.800 --> 01:32:25.440 for in accordance with something that I read 01:32:25.440 --> 01:32:29.080 about 40 years ago on the 01:32:29.080 --> 01:32:32.940 absence of cancer in animals that were fed 01:32:32.940 --> 01:32:40.640 different types of oil coconut oil was safer than olive oil which was safer than 01:32:42.680 --> 01:32:47.800 safflower oil and the polyunsaturated but the safest of them all was 01:32:47.800 --> 01:32:50.960 hydrogenated coconut oil 01:32:50.960 --> 01:32:53.960 Recently I found a place 01:32:53.960 --> 01:32:56.840 to get some 01:32:56.840 --> 01:32:59.920 Just to try it out and it has a very nice 01:32:59.920 --> 01:33:08.040 Clean taste and texture and it's it's free of trans fatty acids as well as polyunsaturated fats. No blues 01:33:08.040 --> 01:33:10.800 the supplier 01:33:11.240 --> 01:33:14.240 Doesn't supply a retail only 01:33:14.240 --> 01:33:18.680 Car lot loads. So did you get a semi is it parked out back? 01:33:18.680 --> 01:33:22.280 Behind your house 01:33:22.280 --> 01:33:24.960 Was a very 01:33:24.960 --> 01:33:30.640 Involved process to get oh, yeah a few gallons of it. Well, sometimes you can 01:33:30.640 --> 01:33:35.760 Say you're thinking of buying a semi, but you just want a sample. Yeah. Yeah 01:33:35.760 --> 01:33:39.720 Well, that's interesting. Did some of the animals get to eat butter? 01:33:40.240 --> 01:33:41.760 Oh 01:33:41.760 --> 01:33:42.880 Yeah 01:33:42.880 --> 01:33:46.880 Butter and coconut oil. Uh-huh. We're the safest natural oils 01:33:46.880 --> 01:33:53.760 Okay, and so let's talk about this is another thing that confuses me about oxidation reduction is sometimes 01:33:53.760 --> 01:33:56.040 They refer to it as hydrogen 01:33:56.040 --> 01:33:59.000 hydrogenation or dehydrogenation 01:33:59.000 --> 01:34:02.840 But they're still talking about oxidation and reduction, aren't they? 01:34:02.840 --> 01:34:05.960 Yeah, it's just a movement of 01:34:05.960 --> 01:34:08.920 electrons that 01:34:09.360 --> 01:34:11.360 they're talking about the 01:34:11.360 --> 01:34:14.360 when we 01:34:14.360 --> 01:34:16.440 make what when we 01:34:16.440 --> 01:34:22.880 Turn saturated fat into unsaturated fat in our own bodies 01:34:22.880 --> 01:34:25.840 we 01:34:25.840 --> 01:34:28.080 Dehydrogenated 01:34:28.080 --> 01:34:30.080 And when a cow turns 01:34:30.080 --> 01:34:36.500 Unsaturated fat from their food into saturated fat for the butter 01:34:38.280 --> 01:34:44.120 It's bacteria in their intestine and rumen which is saturating it 01:34:44.120 --> 01:34:47.320 hydrogenating it so 01:34:47.320 --> 01:34:51.040 Dehydrogenation 01:34:51.040 --> 01:34:53.040 it is 01:34:53.040 --> 01:34:55.240 Something that we do 01:34:55.240 --> 01:35:02.240 In our own body I see and maybe you could describe for us 01:35:03.720 --> 01:35:09.280 What is actually happening to the molecule is it you're actually removing the hydrogen and then that's what 01:35:09.280 --> 01:35:15.880 They're actually referring to the electron 01:35:15.880 --> 01:35:22.120 the movement of electrons out of the bonds is what makes a difference and 01:35:22.120 --> 01:35:23.880 the 01:35:23.880 --> 01:35:29.560 The usual thing that you move is a hydrogen atom or two hydrogen atoms 01:35:29.560 --> 01:35:32.440 And when you take those away 01:35:33.600 --> 01:35:35.160 the 01:35:35.160 --> 01:35:37.160 like if it's on 01:35:37.160 --> 01:35:38.680 the 01:35:38.680 --> 01:35:42.800 to a draining carbon atoms in a fat molecule 01:35:42.800 --> 01:35:50.600 There was a bond of two electrons between the carbons you take away a hydrogen from each one 01:35:50.600 --> 01:35:53.560 and it takes 01:35:53.560 --> 01:36:00.560 It's the proton and one electron leave in each case and they combine 01:36:01.560 --> 01:36:03.560 to hydrogen atoms 01:36:03.560 --> 01:36:09.480 Turn into hydrogen gas or go to some other molecule and the left behind 01:36:09.480 --> 01:36:12.960 Electrons 01:36:12.960 --> 01:36:20.000 Join with each other. So you get a double bond for electrons and joining those carbon atoms and 01:36:20.000 --> 01:36:23.160 the absence of 01:36:23.160 --> 01:36:27.120 This space filling hydrogen 01:36:28.480 --> 01:36:32.040 Seems to leave that range of 01:36:32.040 --> 01:36:37.080 electrons between carbons open and more reactive 01:36:37.080 --> 01:36:40.920 So the 01:36:40.920 --> 01:36:46.960 when you get a lot of hydrogens removed that makes 01:36:46.960 --> 01:36:55.200 Access of oxygen atoms to the fat molecule easier. Hmm. I 01:36:56.640 --> 01:37:03.320 See so that's why Crisco is actually a liquid oil, but it's been had the hydrogen added to it and that 01:37:03.320 --> 01:37:06.120 Makes it more stable 01:37:06.120 --> 01:37:10.560 Yeah, and if they would complete the process the way they do in 01:37:10.560 --> 01:37:17.700 Changing coconut oil from two or three percent PUFA to zero percent PUFA 01:37:17.700 --> 01:37:20.080 you wouldn't get the 01:37:20.080 --> 01:37:22.400 trans-fat 01:37:22.400 --> 01:37:24.160 in it and 01:37:24.160 --> 01:37:26.160 so you would have 01:37:26.600 --> 01:37:28.600 totally saturated and 01:37:28.600 --> 01:37:30.320 mostly 01:37:30.320 --> 01:37:32.120 stearic acid 01:37:32.120 --> 01:37:34.120 In Crisco and that would be safe 01:37:34.120 --> 01:37:39.920 One group of researchers found that aged 01:37:39.920 --> 01:37:42.920 defective mitochondria 01:37:42.920 --> 01:37:45.040 That were not respiring 01:37:45.040 --> 01:37:47.000 properly 01:37:47.000 --> 01:37:48.360 when they 01:37:48.360 --> 01:37:50.400 Gave them fully saturated 01:37:52.240 --> 01:37:54.240 I think was peanut oil 01:37:54.240 --> 01:37:57.400 Restored mitochondrial function Wow 01:37:57.400 --> 01:38:01.000 So it's a it's a way of purifying it. Um 01:38:01.000 --> 01:38:03.760 yeah, and and it 01:38:03.760 --> 01:38:06.800 Eliminates the 01:38:06.800 --> 01:38:12.200 Unstable quality that makes things susceptible to oxidation 01:38:12.200 --> 01:38:15.240 There 01:38:15.240 --> 01:38:17.240 Physiologically, there's something called the 01:38:18.040 --> 01:38:24.520 saturation index you can look at a person's red blood cells and find the ratio of 01:38:24.520 --> 01:38:28.920 stearic acid fully saturated to linoleic acid 01:38:28.920 --> 01:38:33.080 or linoleic different degrees of 01:38:33.080 --> 01:38:36.280 unsaturation and 01:38:36.280 --> 01:38:38.480 and the longer 01:38:38.480 --> 01:38:45.040 Even more unsaturated and people with cancer have a low saturation index 01:38:45.040 --> 01:38:47.040 It's a very stabilizing thing to yeah, like like a newborn baby is highly saturated in its fats 01:38:47.040 --> 01:39:04.480 In recent years a lot of 01:39:04.480 --> 01:39:13.360 Nutrition oriented doctors are saying you must give babies fish oil. Oh god other highly 01:39:14.120 --> 01:39:17.640 highly unsaturated things because most babies are born 01:39:17.640 --> 01:39:27.080 Deficient in the essential fatty acids, but that's the normal state of a newborn. Yeah animal. That's strange because 01:39:27.080 --> 01:39:29.960 It just shows how disconnected 01:39:29.960 --> 01:39:33.920 The medical authorities are with nature. I 01:39:38.040 --> 01:39:45.440 Mean if you'd ever look for anything to for an idea of what perfection is you I think you'd look at a newborn creature 01:39:45.440 --> 01:39:50.960 Yeah, the rate of oxidation is highest 01:39:50.960 --> 01:39:55.840 I'm not not sure how much 01:39:55.840 --> 01:40:02.040 how you would compare the prenatal oxidative state but right at 01:40:02.040 --> 01:40:05.000 the newborn the 01:40:06.960 --> 01:40:08.920 Consumption of 01:40:08.920 --> 01:40:15.240 Oxygen and the sugar per gram of tissue is higher than it will ever be later 01:40:15.240 --> 01:40:17.760 And it decreases 01:40:17.760 --> 01:40:22.800 Especially at puberty with the the rise of the sex hormones 01:40:22.800 --> 01:40:25.520 the oxidation rate 01:40:25.520 --> 01:40:31.720 decreases more sharply and mortality rate increases as the 01:40:31.720 --> 01:40:35.360 Oxidation rate decreases 01:40:36.560 --> 01:40:38.560 Right, so 01:40:38.560 --> 01:40:40.920 That makes perfect sense 01:40:40.920 --> 01:40:44.840 now I better get back to my questions here from 01:40:44.840 --> 01:40:52.520 Interested people Martin asks about salt and these are three questions about salt and 01:40:52.520 --> 01:40:55.580 I'll just run through them as quickly as I can 01:40:55.580 --> 01:41:00.280 Can salt ingestion trigger migraines in 01:41:01.040 --> 01:41:07.040 Some predisposed people example mass max gerson and what would be the cycle? 01:41:07.040 --> 01:41:10.120 I excuse me, what would be the physiological explanation? 01:41:10.120 --> 01:41:14.240 Shall I read them all or do you want to take them one at a time? Oh 01:41:14.240 --> 01:41:19.720 Are they related to the salt? Yeah, they're all about salt restriction 01:41:19.720 --> 01:41:22.640 Yeah 01:41:22.640 --> 01:41:30.120 The others, okay. Here's number two. Here's number two. Do you believe salt restriction was useful in the University of Munich's? 01:41:30.520 --> 01:41:31.920 1928 01:41:31.920 --> 01:41:39.040 Tuberculosis trial with Max Gerson's diet under the supervision of Ferdinand sour brush if yes 01:41:39.040 --> 01:41:44.120 was the beneficial effect due to a release of excess intracellular water and 01:41:44.120 --> 01:41:50.880 three if salt restriction is useful in evacuating excess intracellular water present in 01:41:50.880 --> 01:41:56.120 Degenerative diseases is it useful to keep restricting it once this excess? 01:41:57.000 --> 01:42:04.220 Intercellular water has been evacuated should cancer patients keep avoiding salt after a few months of a saltless diet 01:42:04.220 --> 01:42:12.720 Um, yeah, I read Gerson's book and he was 01:42:12.720 --> 01:42:16.760 Very very good 01:42:16.760 --> 01:42:18.840 thorough 01:42:18.840 --> 01:42:25.520 Saw the effects of the diet first on migraines and then tuberculosis and then cancer 01:42:26.640 --> 01:42:28.280 and 01:42:28.280 --> 01:42:30.400 He tried to understand it and he 01:42:30.400 --> 01:42:36.320 Seems to have read that just about everything in the first half of the century 01:42:36.320 --> 01:42:38.960 on the subject 01:42:38.960 --> 01:42:41.360 and 01:42:41.360 --> 01:42:45.500 The the salts are extremely important the other 01:42:45.500 --> 01:42:49.880 Contemporary of his 01:42:49.880 --> 01:42:53.920 Cancer researcher 01:42:54.320 --> 01:42:57.520 Had a very interesting parallel 01:42:57.520 --> 01:43:02.680 Set of facts regarding salt 01:43:02.680 --> 01:43:10.840 William Frederick Koch who was a chemistry professor at Michigan 01:43:10.840 --> 01:43:14.960 Early in the century 01:43:14.960 --> 01:43:20.680 Was studying the removal of the parathyroid glands 01:43:20.680 --> 01:43:23.680 and a 01:43:23.920 --> 01:43:26.160 calcium supplement was 01:43:26.160 --> 01:43:31.600 The typical remedy for the cramping 01:43:31.600 --> 01:43:42.680 Reaction to the removal of the parathyroid and the doctrine was developed that the parathyroid 01:43:42.680 --> 01:43:44.680 regulates 01:43:44.680 --> 01:43:50.640 Calcium and and so you need to replace calcium when the gland is removed but 01:43:50.640 --> 01:43:52.800 Koch 01:43:52.800 --> 01:43:57.760 Did the surgery on animals and found that if he gave them? 01:43:57.760 --> 01:44:00.080 extra 01:44:00.080 --> 01:44:05.160 Potassium or sodium or magnesium it had the same purity of effect 01:44:05.160 --> 01:44:09.080 And 01:44:09.080 --> 01:44:11.440 The 01:44:11.440 --> 01:44:15.080 Essential fact was that one of these 01:44:15.080 --> 01:44:17.320 can 01:44:17.320 --> 01:44:20.440 make up for a deficiency of the other and 01:44:21.480 --> 01:44:25.040 The Gerson diet was extremely high in 01:44:25.040 --> 01:44:29.600 The other minerals especially potassium 01:44:29.600 --> 01:44:32.880 and 01:44:32.880 --> 01:44:35.720 There the diet always had 01:44:35.720 --> 01:44:43.320 The amount of sodium that you would have in in juice leaves and fruits and vegetables and so on 01:44:43.320 --> 01:44:46.080 so it was always a 01:44:46.080 --> 01:44:48.800 physiological amount of sodium but 01:44:49.120 --> 01:44:53.520 often a very excessive large amount of potassium and 01:44:53.520 --> 01:45:03.080 Magnesium and I think these were the essence of Gerson's success rather than 01:45:03.080 --> 01:45:05.800 just the 01:45:05.800 --> 01:45:07.800 reducing sodium because 01:45:07.800 --> 01:45:11.160 When you look at particular experiments 01:45:11.160 --> 01:45:17.440 Sodium it can stimulate the respiration of a cell and 01:45:17.440 --> 01:45:19.400 and 01:45:19.400 --> 01:45:21.400 Cause it to 01:45:21.400 --> 01:45:24.240 Unswell give up excess water 01:45:24.240 --> 01:45:26.640 if you 01:45:26.640 --> 01:45:31.960 Lower the the other minerals and give it too much sodium you can force it 01:45:31.960 --> 01:45:41.040 To swell and take up water, but it's normal physiological function is to act as a stimulant 01:45:41.040 --> 01:45:45.800 Calcium tends to do to do the same but 01:45:45.800 --> 01:45:47.800 the 01:45:47.800 --> 01:45:51.920 Cell normally is excluding sodium and 01:45:51.920 --> 01:46:01.360 It perceives sodium as an irritant or stimulant and revs up its oxidative metabolism 01:46:01.360 --> 01:46:04.840 When it 01:46:04.840 --> 01:46:11.280 Has a little extra sodium and the increased oxidative metabolism 01:46:12.760 --> 01:46:15.720 Produces carbon dioxide and restores the balance 01:46:15.720 --> 01:46:18.840 So when they're in balance 01:46:18.840 --> 01:46:23.080 The right amount of sodium is increasing 01:46:23.080 --> 01:46:28.440 energy production and decreasing cell water content 01:46:28.440 --> 01:46:32.080 And the 01:46:32.080 --> 01:46:36.600 Much of this stuff 01:46:36.600 --> 01:46:38.440 hadn't 01:46:38.440 --> 01:46:39.560 been 01:46:39.560 --> 01:46:41.560 specifically examined during 01:46:41.800 --> 01:46:47.360 Gerson's lifetime, but he was definitely on to something and was curing 01:46:47.360 --> 01:46:49.640 migraine and cancer 01:46:49.640 --> 01:46:51.640 but he 01:46:51.640 --> 01:46:57.280 very typically would give his patients a couple of grains of armor thyroid and 01:46:57.280 --> 01:47:05.160 Very often coffee enemas and and they were always having a 01:47:05.160 --> 01:47:09.760 Very high ratio of carbohydrate to 01:47:10.760 --> 01:47:16.360 protein so they were low on the methionine and tryptophan and the 01:47:16.360 --> 01:47:19.960 Potentially toxic amino acids 01:47:19.960 --> 01:47:23.880 And 01:47:23.880 --> 01:47:27.520 Generally lots of things in this program 01:47:27.520 --> 01:47:31.640 were very well well founded but 01:47:31.640 --> 01:47:40.360 There just wasn't enough information at that time about about how the balance of the alkaline minerals works 01:47:41.240 --> 01:47:44.920 Yeah, and it sounds like there's so many variables going on there that it would be hard to 01:47:44.920 --> 01:47:47.640 pin down any one 01:47:47.640 --> 01:47:49.640 cause or 01:47:49.640 --> 01:47:51.760 Yep, the 01:47:51.760 --> 01:47:53.240 aldosterone 01:47:53.240 --> 01:47:56.920 One of my first physiological experiments was on myself 01:47:56.920 --> 01:48:02.280 When I worked in the woods our cook was cracked on the idea that 01:48:02.280 --> 01:48:08.520 hard physical labor meant you sweated a lot and needed to replenish your salt and 01:48:09.840 --> 01:48:15.360 That so he would put I think it was about a tablespoon of salt in everyone's porridge in the morning 01:48:15.360 --> 01:48:20.060 if you didn't eat your porridge, you didn't get your ham and eggs on steak and 01:48:20.060 --> 01:48:24.440 Everyone doing it and I 01:48:24.440 --> 01:48:28.720 Within a few days of doing that. I found that 01:48:28.720 --> 01:48:35.600 The sweat that dripped down my forehead was leaving salt crystal trails on my glasses 01:48:36.080 --> 01:48:38.720 And my eyebrows looked like they were 01:48:38.720 --> 01:48:42.200 coated with snow from the salt crystals and 01:48:42.200 --> 01:48:44.880 I 01:48:44.880 --> 01:48:52.760 Thought of the trick of saying that I had been put on a low salt diet. So I got normal porridge 01:48:52.760 --> 01:48:55.600 here from then on and 01:48:55.600 --> 01:48:59.280 Immediately I I could sweat distilled water 01:48:59.280 --> 01:49:01.640 and 01:49:01.640 --> 01:49:03.080 have I 01:49:03.080 --> 01:49:07.160 On the high salt diet. I had to take salt salt pills 01:49:07.160 --> 01:49:09.240 about 01:49:09.240 --> 01:49:11.240 11 o'clock in the morning 01:49:11.240 --> 01:49:16.800 Otherwise, I started getting faint needed to replenish the salt was pouring out so fast 01:49:16.800 --> 01:49:23.200 But after the low salt diet, I never needed afternoon salt pills again 01:49:23.200 --> 01:49:28.360 You mean the overdose of salt sort of stopped your body from being able to regulate it properly 01:49:28.360 --> 01:49:30.800 yeah, and and the 01:49:30.800 --> 01:49:32.280 when you're 01:49:32.280 --> 01:49:34.720 Cutting back on the sodium 01:49:34.720 --> 01:49:40.040 One of the first reactions is that your aldosterone is 01:49:40.040 --> 01:49:42.640 increased 01:49:42.640 --> 01:49:44.640 and aldosterone 01:49:44.640 --> 01:49:49.920 Lets you retain the sodium, but it doesn't at the expense of 01:49:49.920 --> 01:49:52.920 losing some potassium and magnesium 01:49:52.920 --> 01:49:57.760 So if your diet is high in calcium and magnesium 01:49:57.760 --> 01:50:01.400 And 01:50:02.040 --> 01:50:03.360 Potassium 01:50:03.360 --> 01:50:06.640 then there isn't any problem with the 01:50:06.640 --> 01:50:09.560 low sodium intake but 01:50:09.560 --> 01:50:14.760 chronically that high aldosterone has a 01:50:14.760 --> 01:50:19.680 pro-inflammatory effect and and so chronically 01:50:19.680 --> 01:50:27.520 Getting more of all of the alkaline minerals than you really need is a safety precaution that 01:50:28.240 --> 01:50:33.320 will suppress your aldosterone and protect your heart from 01:50:33.320 --> 01:50:39.880 Inflammation and fibrosis and hypertension and so on so in the long run 01:50:39.880 --> 01:50:50.120 Sodium has this protection against cell swelling inflammation fibrosis inflammation 01:50:50.120 --> 01:50:56.200 And in if taken in reasonable amounts it tastes good too 01:50:57.080 --> 01:51:02.320 And what about can salt ingestion trigger migraines in some predisposed people? 01:51:02.320 --> 01:51:05.320 Yeah, when when you're 01:51:05.320 --> 01:51:07.680 already 01:51:07.680 --> 01:51:09.680 on a low salt diet and 01:51:09.680 --> 01:51:15.720 Take salt one of the common physiology experiments is to 01:51:15.720 --> 01:51:18.560 have people 01:51:18.560 --> 01:51:23.560 drink a quart of plain water or a quart of plain water with a 01:51:23.560 --> 01:51:25.720 heaping 01:51:25.720 --> 01:51:27.720 teaspoon of salt added to it and 01:51:27.720 --> 01:51:31.080 at the end of the physiology lab 01:51:31.080 --> 01:51:35.560 Everyone who got the unsalted quarter water 01:51:35.560 --> 01:51:43.520 Would have formed about a quart of urine and the ones that got the salt didn't have any extra forming 01:51:43.520 --> 01:51:47.200 And it took a usually a couple days 01:51:47.200 --> 01:51:50.840 For that excess water to to come out 01:51:51.400 --> 01:51:56.920 So when you take a sudden dose of salt it makes you swell up and retain water 01:51:56.920 --> 01:51:59.840 until your 01:51:59.840 --> 01:52:05.720 Aldosterone has adjusted downward. I see so it just takes a while to do it adjust to it 01:52:05.720 --> 01:52:08.520 Yeah, and you'll notice 01:52:08.520 --> 01:52:12.160 Anything that is 01:52:12.160 --> 01:52:16.680 Susceptible will swell up your fingers and toes and and lips and 01:52:17.360 --> 01:52:22.680 eyelids and such might swell up in the first day after you eat a lot of salt, but 01:52:22.680 --> 01:52:24.960 people who 01:52:24.960 --> 01:52:29.860 For example on a long airplane trip would always get swollen feet 01:52:29.860 --> 01:52:36.440 If they adjusted two or three days in advance by eating extra salt on some baking soda 01:52:36.440 --> 01:52:42.680 They didn't get swollen feet from sitting still anymore. Huh? I 01:52:42.680 --> 01:52:45.400 see, so 01:52:45.400 --> 01:52:51.480 So you're retaining the you're retaining the liquid then and in a different place or are you not? 01:52:51.480 --> 01:52:54.840 No, you're suppressing the aldosterone. So it 01:52:54.840 --> 01:52:57.600 Gets the water out of you 01:52:57.600 --> 01:53:02.280 the one of the ways sodium works is 01:53:02.280 --> 01:53:05.520 the albumin molecule is 01:53:05.520 --> 01:53:09.800 full of negative charges and it holds 01:53:09.800 --> 01:53:13.240 the sodium 01:53:13.400 --> 01:53:16.480 In in association so you get a cloud of 01:53:16.480 --> 01:53:22.840 positive negative charges which holds on the water it 01:53:22.840 --> 01:53:25.280 keeps the 01:53:25.280 --> 01:53:27.280 water osmotically 01:53:27.280 --> 01:53:29.800 held in in your bloodstream 01:53:29.800 --> 01:53:35.840 If you're low in either albumin or sodium 01:53:35.840 --> 01:53:37.880 your 01:53:37.880 --> 01:53:39.480 blood itself 01:53:39.480 --> 01:53:41.480 loses the osmotic 01:53:42.040 --> 01:53:46.160 quality and the water stays in your cells and 01:53:46.160 --> 01:53:48.800 extravascular spaces 01:53:48.800 --> 01:53:53.720 When the combination of albumin and sodium is present in the blood 01:53:53.720 --> 01:53:55.480 water 01:53:55.480 --> 01:54:01.920 flows out of the tissues into the blood and the blood passing through the kidneys then 01:54:01.920 --> 01:54:10.120 can get rid of the water that otherwise would sit around in your tissues and 01:54:11.800 --> 01:54:13.800 that same situation 01:54:13.800 --> 01:54:18.600 Impairs circulation because your blood volume is low and the fluid volume 01:54:18.600 --> 01:54:22.680 Outside the blood vessels is is too high. Oh, I see, right 01:54:22.680 --> 01:54:25.640 and the the anti-diuretic 01:54:25.640 --> 01:54:33.680 hormone is a another side of this that is a lot more complicated than and responds to 01:54:33.680 --> 01:54:36.000 distress 01:54:36.000 --> 01:54:43.720 Estrogen and and a lot of other things where the aldosterone is is pretty closely related to the mineral balance 01:54:43.720 --> 01:54:49.840 And what is the anti-diuretic hormone? Is that what are you calling? What is that? 01:54:49.840 --> 01:54:52.400 It's a pituitary 01:54:52.400 --> 01:54:53.640 hormone 01:54:53.640 --> 01:54:56.200 that causes water retention 01:54:56.200 --> 01:54:59.160 with sodium loss 01:54:59.160 --> 01:55:01.680 and a 01:55:01.680 --> 01:55:03.680 low thyroid person 01:55:03.680 --> 01:55:05.880 old people 01:55:06.240 --> 01:55:08.240 people after accidents 01:55:08.240 --> 01:55:10.800 anyone in serious stress 01:55:10.800 --> 01:55:17.040 The they call it inappropriate secretion of anti-diuretic hormone 01:55:17.040 --> 01:55:21.200 syndrome and that's very common where 01:55:21.200 --> 01:55:24.280 edema is the 01:55:24.280 --> 01:55:33.080 What what is really harmful the brain swells up for example, because the body has too much water and not enough salt 01:55:33.080 --> 01:55:35.480 and 01:55:35.480 --> 01:55:37.480 the remedy for that 01:55:37.480 --> 01:55:40.360 is 01:55:40.360 --> 01:55:42.560 Just adding sodium but 01:55:42.560 --> 01:55:48.280 That's not fundamental and if you do it too fast, you disturb the balance in the different compartments 01:55:48.280 --> 01:55:52.920 but the basic reason for it is that you aren't producing the 01:55:52.920 --> 01:55:57.200 carbon dioxide from a thyroid deficiency and 01:55:57.200 --> 01:56:00.080 the absence of the 01:56:00.080 --> 01:56:03.760 high production of carbon dioxide means that you aren't able to 01:56:04.680 --> 01:56:09.320 retain the sodium in your kidneys as as the water passes through 01:56:09.320 --> 01:56:14.680 and so the low thyroid person loses sodium because the 01:56:14.680 --> 01:56:18.480 Reverse of the process that 01:56:18.480 --> 01:56:21.800 happens in other cells in the kidneys 01:56:21.800 --> 01:56:25.320 carbon dioxide allows the cells to 01:56:25.320 --> 01:56:28.240 catch and retain sodium 01:56:28.240 --> 01:56:31.840 Well, that's fascinating and 01:56:33.360 --> 01:56:39.000 Can't say I get it all but I understand it a little bit that's that's very interesting Ray. Thanks for 01:56:39.000 --> 01:56:46.280 explaining all that and I had more questions, but I didn't have any more from other people I think I got I got to them all and 01:56:46.280 --> 01:56:49.400 anything you want to say to 01:56:49.400 --> 01:56:51.520 sum up about 01:56:51.520 --> 01:56:57.400 Staying healthy and keeping your oxidation working. Well, we have about two minutes. Oh 01:56:59.200 --> 01:57:03.480 Just keeping stress down and the fun up 01:57:03.480 --> 01:57:07.520 Judging food by 01:57:07.520 --> 01:57:15.320 Largely by how it tastes rather than by what the experts say. Okay. Well, that's easy advice to follow 01:57:15.320 --> 01:57:21.640 so on that note Ray, I really want to thank you for coming on these last two shows and 01:57:21.640 --> 01:57:27.920 And I'll tell people how to get in touch with your website if they want to read more 01:57:28.320 --> 01:57:30.320 Then I'll say goodbye 01:57:30.320 --> 01:57:34.040 Okay. All right. You thank you so much. Thank you so much, Ray 01:57:34.040 --> 01:57:36.880 Yep, bye