@Article{Denti2018, author="Denti, Luca and Rizzi, Raffaella and Beretta, Stefano and Vedova, Gianluca Della and Previtali, Marco and Bonizzoni, Paola", title="ASGAL: aligning RNA-Seq data to a splicing graph to detect novel alternative splicing events", journal="BMC Bioinformatics", year="2018", month="Nov", day="20", volume="19", number="1", pages="444", abstract="While the reconstruction of transcripts from a sample of RNA-Seq data is a computationally expensive and complicated task, the detection of splicing events from RNA-Seq data and a gene annotation is computationally feasible. This latter task, which is adequate for many transcriptome analyses, is usually achieved by aligning the reads to a reference genome, followed by comparing the alignments with a gene annotation, often implicitly represented by a graph: the splicing graph.", issn="1471-2105", doi="10.1186/s12859-018-2436-3", url="https://doi.org/10.1186/s12859-018-2436-3" }