# Frequently asked questions A plain-language reference for researchers evaluating MedSci Skills, and a search/answer-engine-friendly summary of what it is and is not. ## What is MedSci Skills? MedSci Skills is an open-source Claude Code skill collection for **clinical manuscript preparation**. It helps physician-researchers and biomedical investigators move from literature search, study design, statistics, and figures to reporting-guideline compliance, citation/reference auditing, numerical-consistency checks, and response-to-reviewer workflows. It combines agentic writing workflows with **deterministic integrity gates** for submission-grade biomedical research. ## Who should use it? Physician-researchers, biomedical investigators, and research teams writing clinical, diagnostic-accuracy, observational, or systematic-review/meta-analysis manuscripts — especially in radiology and medical AI, where the bundled reporting guidelines and journal profiles are deepest. ## Is MedSci Skills a "medical writing AI"? Does it replace human authors? No. It is workflow tooling with deterministic checks, not an autonomous author. It **does not replace** authors, statisticians, reviewers, IRBs, or journal requirements, and every output **requires human-expert verification**. Its goal is to make manuscripts more auditable and reproducible and to reduce common preparation errors — not to write the paper for you. ## Is it clinically validated? Is it a clinical/diagnostic tool? No. MedSci Skills is **not** a clinical-decision-support or diagnostic tool and makes no clinical-validation claim about itself. It supports manuscript and research **workflow** only (see [`SECURITY.md`](../SECURITY.md) for the scope boundary). ## Does it check STROBE, PRISMA, STARD (and other guidelines)? Yes. It bundles a set of EQUATOR-network reporting checklists and risk-of-bias / appraisal tools (STROBE, CONSORT and CONSORT-AI, STARD and STARD-AI, PRISMA and PRISMA-DTA, TRIPOD and TRIPOD+AI, QUADAS-2, RoB 2, ROBINS-I, AMSTAR 2, and more) and audits a manuscript item by item. The authoritative current list and count are in [`metadata/catalog_counts.json`](../metadata/catalog_counts.json) and the [README](../README.md). ## Can it verify references and citations? Yes. References are checked against PubMed / CrossRef / OpenAlex (including first-author and full-author cross-checks) before they are trusted; the toolkit never writes references from model memory. See `/verify-refs`. ## Can it detect numerical inconsistencies? Yes. Deterministic detectors check numerical and cohort arithmetic, pooled-estimate consistency, and cross-artifact drift across the manuscript, tables, figures, and submission package. These are part of the **MedSci-Audit** detector layer (see [`MEDSCI_AUDIT.md`](../MEDSCI_AUDIT.md)). ## How is it different from a general AI writing assistant? A general assistant drafts prose. MedSci Skills adds the clinical-submission layer a generic tool lacks: reporting-guideline audits, reference verification, numerical / cross-artifact consistency gates, journal-specific profiles, and ICMJE/IRB form support — deterministic checks that run before a reviewer sees the manuscript. ## How is it different from a general "AI scientist" agent? It is intentionally narrow. It does not span chemistry, drug discovery, or bench biology, and it is not an autonomous research agent. It is one physician-researcher's clinical-manuscript pipeline with integrity gates (see [`ROADMAP.md`](../ROADMAP.md) for the scope boundary). ## Is it free and open-source? Yes — MIT licensed (see [`LICENSE`](../LICENSE); note any per-file carve-outs noted in the file headers). ## How widely adopted is it? It has **early community adoption signals** (stars, forks, and a few named uses) for a niche biomedical-workflow repository — not widespread adoption. The honest, continuously updated record is in [`IMPACT.md`](../IMPACT.md). ## How do I cite MedSci Skills? Use [`CITATION.cff`](../CITATION.cff) or the archived Zenodo DOI listed in the [README](../README.md).