CIDO: Ontology of Coronavirus Infectious Disease
type: Ontology
version IRI: cido.owl
Contributor: Barry Smith
Contributor: Brian Athey
Contributor: Gil Omenn
Contributor: Hongfang Liu
Contributor: Ghida Arnous
creator: Anthony Huffman
creator: Ashley Yan
creator: Asiyah Yu Lin
creator: Bill Duncan
creator: Easheta Shah
creator: Edison Ong
creator: Ghida Arnous
creator: Guirui Huang (Ray)
creator: Hong Yu
creator: Hsin-Hui Huang
creator: Jie Zheng
creator: John Beverley
creator: Liwei Wang
creator: Muhui Ye
creator: Roshan Desai
creator: Sivaram Arabandi
creator: Suyuan Peng
creator: Yang Wang
creator: Yingtong Liu
creator: Yongqun "Oliver" He (YOH)
creator: Yujia Tian
creator: Zalan Shah
creator: Zhigang Wang
description: The Ontology of Coronavirus Infectious Disease (CIDO) is a community-driven open-source biomedical ontology in the area of coronavirus infectious disease. The CIDO is developed to provide standardized human- and computer-interpretable annotation and representation of various coronavirus infectious diseases, including their etiology, transmission, pathogenesis, diagnosis, prevention, and treatment.
Format: OWL-DL
subject: CIDO: A biomedical ontology in the area of coronavirus infectious disease.
license: http://creativecommons.org/licenses/by/4.0/
version info: 2024-02-16

Display_Name
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C264
imported from: NDF-RT.owl

FDA_UNII
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C12847068852884
imported from: NDF-RT.owl

Level
type: AnnotationProperty
type: DatatypeProperty
range: Datatype
  one of: Ingredient
  one of: Ingredient Strength
  one of: Packaged Product
  one of: VA Class
  one of: VA Product
type: NamedIndividual
code: C98
imported from: NDF-RT.owl

MeSH_CUI
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C176
imported from: NDF-RT.owl

MeSH_DUI
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C134
imported from: NDF-RT.owl

MeSH_Definition
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C142
imported from: NDF-RT.owl

MeSH_Name
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C287
imported from: NDF-RT.owl

NUI
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C10490107818172
imported from: NDF-RT.owl

RxNorm_CUI
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C818
imported from: NDF-RT.owl

RxNorm_Name
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C819
imported from: NDF-RT.owl

SNOMED_CID
type: AnnotationProperty
range: string
type: DatatypeProperty
code: C28502475289736
imported from: NDF-RT.owl

Status
type: AnnotationProperty
type: DatatypeProperty
range: Datatype
  one of: Active
  one of: Inactive
code: C27489601424203
imported from: NDF-RT.owl

Synonym
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C136
imported from: NDF-RT.owl

UMLS_CUI
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C140
imported from: NDF-RT.owl

VANDF_Record
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C262721
imported from: NDF-RT.owl

VUID
type: AnnotationProperty
range: string
type: DatatypeProperty
type: NamedIndividual
code: C262777
imported from: NDF-RT.owl

code
type: AnnotationProperty
range: string
type: DatatypeProperty
code: AHC0
read only: true
imported from: NDF-RT.owl

BFO OWL specification label
type: AnnotationProperty
editor preferred label: BFO OWL specification label
definition: Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.
curator note: Really of interest to developers only
sub property of: label

BFO CLIF specification label
type: AnnotationProperty
editor preferred label: BFO CLIF specification label
definition: Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2
definition source: Person:Alan Ruttenberg
curator note: Really of interest to developers only
sub property of: label

Chinese label
type: AnnotationProperty

FDA EUA laboratory,company or organization
type: AnnotationProperty
definition: An annotation property that represents a laboratory, company or organization authorized by FDA emergency use authorization (EUA) to perform an assay such as a SARS-CoV-2 RT-PCR assay.
definition editor: Asiyah Yu Lin, Oliver He
definition source: https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization

Interaction detection method
type: AnnotationProperty
definition editor: ZW, GH, SP, YH
definition source: An annotation property that represents an annotation about an interaction detection method, which may include its name and code such as MI code

has text mining keywords
type: AnnotationProperty
definition: An annotation property that provides one or more keywords useful for text mining of the indicated ontology term.
definition editor: Liwei Wang, Oliver He

wikidata_ID
type: AnnotationProperty
creator: Asiyah Yu Lin
date: 2021-09-08T02:48:51Z

Interaction type
type: AnnotationProperty
definition: An annotation property that represents an annotation about an interaction type, which may include its name and code such as MI code
definition editor: ZW, GH, SP, YH

has_RxCUI
type: AnnotationProperty

editor preferred label
type: AnnotationProperty
editor preferred label: editor preferred label
editor preferred label: editor preferred term
editor preferred label: editor preferred term~editor preferred label
has curation status: IAO_0000122
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
label: editor preferred term
label: editor preferred term~editor preferred label

example of usage
type: AnnotationProperty
editor preferred label: example
editor preferred label: example of usage
has curation status: IAO_0000122
definition: A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not
definition: A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

has curation status
type: AnnotationProperty
editor preferred label: has curation status
definition editor: PERSON:Alan Ruttenberg
definition editor: PERSON:Bill Bug
definition editor: PERSON:Melanie Courtot
definition source: OBI_0000281

definition
type: AnnotationProperty
editor preferred label: definition
editor preferred label: textual definition
has curation status: IAO_0000122
definition: English language definitions of what NCI means by the concept. These are limited to 1024 characters. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
definition: The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition.
editor note: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
has exact synonym: DEFINITION
label: textual definition

editor note
type: AnnotationProperty
editor preferred label: editor note
has curation status: IAO_0000122
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obfoundry.org/obo/obi>
definition source: GROUP:OBI:<http://purl.obofoundry.org/obo/obi>
database_cross_reference: IAO:0000116
has_obo_namespace: uberon
id: editor_note
is metadata tag: true
is metadata tag: 1
shorthand: editor_note

definition editor
type: AnnotationProperty
editor preferred label: definition editor
editor preferred label: term editor
has curation status: IAO_0000122
definition: Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people
definition: Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115.
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
label: term editor

alternative term
type: AnnotationProperty
editor preferred label: alternative label
editor preferred label: alternative term
has curation status: IAO_0000125
definition: A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like.
definition: An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)
definition editor: OBO Operations committee
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
comment: Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related).
label: alternative label

definition source
type: AnnotationProperty
editor preferred label: definition source
has curation status: IAO_0000122
definition: Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
definition: formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
definition editor: PERSON:Daniel Schober
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

has obsolescence reason
type: AnnotationProperty
editor preferred label: has obsolescence reason
definition: Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.
definition editor: PERSON:Alan Ruttenberg
definition editor: PERSON:Melanie Courtot

curator note
type: AnnotationProperty
editor preferred label: curator note
has curation status: IAO_0000122
definition: An administrative note of use for a curator but of no use for a user
definition editor: PERSON:Alan Ruttenberg
database_cross_reference: IAO:0000232
has_obo_namespace: uberon
id: curator_notes
is metadata tag: true
is metadata tag: 1
shorthand: curator_notes
label: curator notes

term tracker item
type: AnnotationProperty
editor preferred label: term tracker item
example of usage: the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/
has curation status: IAO_0000125
definition: An IRI or similar locator for a request or discussion of an ontology term.
definition editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
database_cross_reference: IAO:0000233
has_obo_namespace: external
id: term_tracker_item
is class level: true
is metadata tag: true
shorthand: term_tracker_item
comment: The 'tracker item' can associate a tracker with a specific ontology term.

ontology term requester
type: AnnotationProperty
editor preferred label: ontology term requester
has curation status: IAO_0000125
definition: The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.
definition editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
comment: The 'term requester' can credit the person, organization or project who request the ontology term.

imported from
type: AnnotationProperty
editor preferred label: imported from
has curation status: IAO_0000125
definition: For external terms/classes, the ontology from which the term was imported
definition editor: PERSON:Alan Ruttenberg
definition editor: PERSON:Melanie Courtot
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

expand expression to
type: AnnotationProperty

OBO foundry unique label
type: AnnotationProperty
editor preferred label: OBO foundry unique label
has curation status: IAO_0000125
definition: An alternative name for a class or property which is unique across the OBO Foundry.
editor note: The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools .
definition editor: PERSON:Alan Ruttenberg
definition editor: PERSON:Bjoern Peters
definition editor: PERSON:Chris Mungall
definition editor: PERSON:Melanie Courtot
definition source: GROUP:OBO Foundry <http://obofoundry.org/>

elucidation
type: AnnotationProperty
editor preferred label: elucidation
definition editor: person:Alan Ruttenberg
definition source: Person:Barry Smith
elucidation: Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms

has associated axiom(nl)
type: AnnotationProperty
editor preferred label: has associated axiom(nl)
definition editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom associated with a term expressed using natural language

has associated axiom(fol)
type: AnnotationProperty
editor preferred label: has associated axiom(fol)
definition editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom expressed in first order logic using CLIF syntax

term replaced by
type: AnnotationProperty

term_mapping_to_NCIT
type: AnnotationProperty
sub property of: seeAlso

Has_NICHD_Parent
type: AnnotationProperty
definition: A property created to allow the source NICHD to assign a parent to each concept with the intent of creating a hierarchy that includes only terms in which they are the contributing source.
code: A11
Semantic_Type: Conceptual Entity
Preferred_Name: Has_NICHD_Parent
has exact synonym: Has_NICHD_Parent

code
type: AnnotationProperty
read only: true
code: NHC0
Preferred_Name: code
has exact synonym: code

Semantic_Type
type: AnnotationProperty
definition: The semantic type describes the sort of thing or category to which a concept belongs in the context of the UMLS semantic network.
code: P106
Semantic_Type: Conceptual Entity
Display_Name: Semantic Type
Preferred_Name: Semantic_Type
DesignNote: In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS.
has exact synonym: Semantic_Type

Display_Name
type: AnnotationProperty
definition: Provides an alternative Preferred Name for use in some NCI systems.
code: P107
Semantic_Type: Conceptual Entity
Display_Name: Display Name
Preferred_Name: Display_Name
has exact synonym: Display Name
has exact synonym: Display_Name

Preferred_Name
type: AnnotationProperty
definition: The word or phrase that NCI uses by preference to refer to the concept.
code: P108
Semantic_Type: Conceptual Entity
Display_Name: Preferred Name
Preferred_Name: Preferred_Name
has exact synonym: Preferred Name
has exact synonym: Preferred Term
has exact synonym: Preferred_Name

UMLS_CUI
type: AnnotationProperty
definition: Concept Unique Identifiers, or CUIs, are concept numbers assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept.
code: P207
Semantic_Type: Conceptual Entity
Display_Name: UMLS CUI
Preferred_Name: UMLS_CUI
has exact synonym: UMLS_CUI

Contributing_Source
type: AnnotationProperty
definition: This property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake.
code: P322
Semantic_Type: Conceptual Entity
Display_Name: Contributing Source
Preferred_Name: Contributing_Source
has exact synonym: Contributing_Source

ALT_DEFINITION
type: AnnotationProperty
definition: English language definitions of what a source other than NCI means by the concept. These are limited to 1024 characters. They include information about the definition's source in a form that can easily be interpreted by software.
code: P325
Semantic_Type: Conceptual Entity
Display_Name: [source] Definition
Preferred_Name: ALT_DEFINITION
has exact synonym: ALT_DEFINITION

Legacy_Concept_Name
type: AnnotationProperty
read only: true
definition: A retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding.
code: P366
Semantic_Type: Conceptual Entity
Preferred_Name: Legacy Concept Name
has exact synonym: Legacy Concept Name

NICHD_Hierarchy_Term
type: AnnotationProperty
code: P371
Semantic_Type: Conceptual Entity
Preferred_Name: NICHD_Hierarchy_Term
Contributing_Source: NICHD
has exact synonym: NICHD_Hierarchy_Term

DesignNote
type: AnnotationProperty
definition: Design notes are notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept.
code: P98
Semantic_Type: Conceptual Entity
Display_Name: DesignNote
Preferred_Name: DesignNote
has exact synonym: DesignNote

Chinese translation
type: AnnotationProperty
definition editor: YH, JX
comment: a chinese translation represents a chinese translation of the existing term.

adverse event outcome
type: AnnotationProperty
example of usage: The AE 'cough AE' has the 'label of AE outcome' of 'cough'; 'infection AE' has the 'label of AE outcom' of 'infection'.
definition: an annotation property that represents the label of an adverse event
definition editor: Yongqun Oliver He, Jiangan Hardy Xie
alternative term: label of adverse event outcome
sub property of: label

has_MedDRA_id
type: AnnotationProperty

ISA alternative term
type: AnnotationProperty
editor preferred label: ISA alternative term
has curation status: IAO_0000122
definition: An alternative term used by the ISA tools project (http://isa-tools.org).
editor note: Requested by Alejandra Gonzalez-Beltran https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178
definition editor: Person: Alejandra Gonzalez-Beltran
definition editor: Person: Philippe Rocca-Serra
definition source: ISA tools project (http://isa-tools.org)
sub property of: alternative term

NIAID GSCID-BRC alternative term
type: AnnotationProperty
editor preferred label: NIAID GSCID-BRC alternative term
has curation status: IAO_0000122
definition: An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC).
definition editor: PERSON: Chris Stoeckert, Jie Zheng
definition source: NIAID GSCID-BRC metadata working group
sub property of: alternative term

IEDB alternative term
type: AnnotationProperty
editor preferred label: IEDB alternative term
has curation status: IAO_0000122
definition: An alternative term used by the IEDB.
definition editor: PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters
definition source: IEDB
sub property of: alternative term

symbol from nomenclature authority
type: AnnotationProperty
definition: the symbol assigned by the nomenclature authority
definition editor: Oliver He, Yue Liu

full name from nomenclature authority
type: AnnotationProperty
definition: the full name assigned by the nomenclature authority
definition editor: Oliver He, Yue Liu

NCBI GeneID
type: AnnotationProperty
definition: A GeneID in the NCBI Gene database
definition editor: Oliver He, Yue Liu

NCBI LocusTag
type: AnnotationProperty
definition: the NCBI LocusTag name of a gene
definition editor: Oliver He, Yue Liu

gene map location
type: AnnotationProperty
definition: the map location of a gene
definition editor: Oliver He, Yue Liu

modification date
type: AnnotationProperty
definition: a date of content modification
definition editor: Oliver He, Yue Liu

organism NCBITaxon ID
type: AnnotationProperty
definition: The NCBITaxon ontology ID of an organism.
definition editor: Oliver He, Yue Liu

chromosome ID of gene
type: AnnotationProperty
definition: A chromosome ID where a gene is located.
definition editor: Oliver He

type of gene
type: AnnotationProperty
definition: an annotation property that specifies the type of a gene
definition editor: Oliver He

nomenclature status
type: AnnotationProperty
definition: an annotation property that specifies a nomenclature status
definition editor: Oliver He

has GO association
type: AnnotationProperty
definition: an annotation property that shows the GO information associated with a specific gene.
definition editor: Yongqun He
comment: YH: use the convention: GO_ID (EC: xx; Qualifier: xx; PMID: xxxxx;) where GO_ID is a GO ID, EC is the Evidence Code, Qualifier is a specific association type, and PMID is a PubMed ID of a paper that supports the gene-GO association.
domain: OGG_0000000002

has PubMed association
type: AnnotationProperty
definition: An annotation property that represents a gene's association with PubMed publication(s).
definition editor: Yongqun He
comment: YH: use the format: PMID: pmid1, pmid2, ... where pmid1 and pmid2 are specfic PubMed IDs (PMIDs).

term mapping to NCIT ID
type: AnnotationProperty
definition: A subproperty of seeAlso that represents a NCIT identifier mapped to the specified term
definition editor: Oliver He
sub property of: see also

term mapping to UMLS CUI
type: AnnotationProperty
definition: A subproperty of seeAlso that represents a UMLS CUI identifier mapped to the specified term
definition editor: Oliver He
sub property of: see also

alternative term in Chinese
type: AnnotationProperty
sub property of: alternative term

temporal interpretation
type: AnnotationProperty
editor preferred label: temporal interpretation
definition: An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.
sub property of: logical macro assertion on an object property

logical macro assertion
type: AnnotationProperty
definition: An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.

logical macro assertion on a property
type: AnnotationProperty
definition: A logical macro assertion whose domain is an IRI for a property
sub property of: logical macro assertion

logical macro assertion on an object property
type: AnnotationProperty
definition: Used to annotate object properties to describe a logical meta-property or characteristic of the object property.
sub property of: logical macro assertion on a property

logical macro assertion on an annotation property
type: AnnotationProperty
sub property of: logical macro assertion on a property

is direct form of
type: AnnotationProperty
definition: relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y
editor note: The general property hierarchy is: "directly P" SubPropertyOf "P" Transitive(P) Where we have an annotation assertion "directly P" "is direct form of" "P"
logical macro assertion on an annotation property: If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'
creator: Chris Mungall
sub property of: logical macro assertion on an object property

is indirect form of
type: AnnotationProperty
definition: relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y
creator: Chris Mungall
sub property of: logical macro assertion on an object property

is directional form of
type: AnnotationProperty
definition: Used to annotate object properties representing a causal relationship where the value indicates a direction. Should be "+", "-" or "0"
created_by: cjm
creation_date: 2018-03-13T23:59:29Z
sub property of: logical macro assertion on an object property

is positive form of
type: AnnotationProperty
created_by: cjm
creation_date: 2018-03-14T00:03:16Z
sub property of: is directional form of

is negative form of
type: AnnotationProperty
created_by: cjm
creation_date: 2018-03-14T00:03:24Z
sub property of: is directional form of

is homeomorphic for
type: AnnotationProperty
example of usage: part-of is homeomorphic for independent continuants.
definition: R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C.
created_by: cjm
creation_date: 2018-10-21T19:46:34Z
comment: R homeomorphic-for C expands to: C SubClassOf R only C. Additionally, for any class D that is disjoint with C, we can also expand to C DisjointWith R some D, D DisjointWith R some C.
sub property of: logical macro assertion on an object property

external_definition
type: AnnotationProperty
definition: An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class.
database_cross_reference: UBPROP:0000001
has_obo_namespace: uberon
id: external_definition
is metadata tag: true
shorthand: external_definition
comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO

axiom_lost_from_external_ontology
type: AnnotationProperty
definition: A textual description of an axiom loss in this ontology compared to an external ontology.
database_cross_reference: UBPROP:0000002
has_obo_namespace: uberon
id: axiom_lost_from_external_ontology
is metadata tag: true
shorthand: axiom_lost_from_external_ontology
comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO

homology_notes
type: AnnotationProperty
definition: Notes on the homology status of this class.
database_cross_reference: UBPROP:0000003
has_obo_namespace: uberon
id: homology_notes
is metadata tag: true
shorthand: homology_notes
comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO

implements_design_pattern
type: AnnotationProperty
database_cross_reference: UBPROP:0000006
has_obo_namespace: uberon
id: implements_design_pattern
is metadata tag: true
shorthand: implements_design_pattern

has_relational_adjective
type: AnnotationProperty
curator note: Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'.
database_cross_reference: UBPROP:0000007
has_obo_namespace: uberon
id: has_relational_adjective
is metadata tag: true
shorthand: has_relational_adjective

taxon_notes
type: AnnotationProperty
definition: Notes on the how instances of this class vary across species.
database_cross_reference: UBPROP:0000008
has_obo_namespace: uberon
id: taxon_notes
is metadata tag: true
shorthand: taxon_notes

development_notes
type: AnnotationProperty
definition: Notes on the ontogenic development of instances of this class.
editor note: This annotation property may be replaced with an annotation property from an external ontology such as IAO
database_cross_reference: UBPROP:0000011
has_obo_namespace: uberon
id: development_notes
is metadata tag: true
shorthand: development_notes

external_ontology_notes
type: AnnotationProperty
definition: Notes on how similar or equivalent classes are represented in other ontologies.
editor note: This annotation property may be replaced with an annotation property from an external ontology such as IAO
database_cross_reference: UBPROP:0000012
has_obo_namespace: uberon
id: external_ontology_notes
is metadata tag: true
shorthand: external_ontology_notes

fma_set_term
type: AnnotationProperty
external_ontology_notes: FMA has terms like 'set of X'. In general we do not include set-of terms in uberon, but provide a mapping between the singular form and the FMA set term
database_cross_reference: UBPROP:0000202
has_obo_namespace: uberon
id: fma_set_term
is metadata tag: true
shorthand: fma_set_term

trade name
type: AnnotationProperty
definition: An annotation property that represents the trade name of a product.
definition editor: Oliver He

vaccine proper name
type: AnnotationProperty
example of usage: The vaccine Prevnar (trade name) has a FDA-defined proper name: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein). Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm
definition: An annotation property that represents the proper name of a vaccine, which is defined in an official way such as one defined by FDA.
definition editor: Kallan Roan
definition editor: Oliver He

vaccine manufacturer
type: AnnotationProperty
example of usage: The vaccine Prevnar has the manufacturer: Wyeth Pharmaceuticals Inc. Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm
definition: An annotation property that represents the manufacturer of a vaccine
definition editor: Kallan Roan
definition editor: Oliver He

CVX code
type: AnnotationProperty
definition: An annotation property that refers to a specific CVX ID.
definition editor: Oliver He
definition editor: Penny Pan
definition source: https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp

Unique Apollo Label
type: AnnotationProperty
definition: This annotation property gives the unique label of all Apollo_SV entities that are refered to in the schema. The UAL is the denotator for the Apollo_SV class in the schema. There can at all times only be ONE value of UAL for each class.
alternative term: UAL

has_rank
type: AnnotationProperty
definition: A metadata relation between a class and its taxonomic rank (eg species, family)
has_obo_namespace: ncbi_taxonomy

Contributor
type: AnnotationProperty
description: Examples of a Contributor include a person, an organisation, or a service. Typically, the name of a Contributor should be used to indicate the entity.
has_obo_namespace: uberon
id: dc-contributor
is metadata tag: true
shorthand: dc-contributor
comment: An entity responsible for making contributions to the content of the resource.
label: contributor

Creator
type: AnnotationProperty
description: Examples of a Creator include a person, an organisation, or a service. Typically, the name of a Creator should be used to indicate the entity.
comment: An entity primarily responsible for making the content of the resource.

Date
type: AnnotationProperty
description: Typically, Date will be associated with the creation or availability of the resource. Recommended best practice for encoding the date value is defined in a profile of ISO 8601 [W3CDTF] and follows the YYYY-MM-DD format.
comment: A date associated with an event in the life cycle of the resource.

Description
type: AnnotationProperty
description: Description may include but is not limited to: an abstract, table of contents, reference to a graphical representation of content or a free-text account of the content.
comment: An account of the content of the resource.

Format
type: AnnotationProperty
description: Typically, Format may include the media-type or dimensions of the resource. Format may be used to determine the software, hardware or other equipment needed to display or operate the resource. Examples of dimensions include size and duration. Recommended best practice is to select a value from a controlled vocabulary (for example, the list of Internet Media Types [MIME] defining computer media formats).
comment: The physical or digital manifestation of the resource.

Source
type: AnnotationProperty
description: The present resource may be derived from the Source resource in whole or in part. Recommended best practice is to reference the resource by means of a string or number conforming to a formal identification system.
comment: A reference to a resource from which the present resource is derived.

Subject and Keywords
type: AnnotationProperty
description: Typically, a Subject will be expressed as keywords, key phrases or classification codes that describe a topic of the resource. Recommended best practice is to select a value from a controlled vocabulary or formal classification scheme.
comment: The topic of the content of the resource.

license
type: AnnotationProperty
definition editor: Mark Miller
date: 2018-05-11T13:47:29Z

consider
type: AnnotationProperty

created_by
type: AnnotationProperty
definition: Author of the class.

creation_date
type: AnnotationProperty
definition: Date class was created.

has_alternative_id
type: AnnotationProperty
definition: ID of merged class.

has_broad_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more general meaning than the preferred name/primary label.
definition editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/18
label: has broad synonym
sub property of: alternative term

database_cross_reference
type: AnnotationProperty
definition: Reference database or publication source.

has_definition
type: AnnotationProperty

has exact synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.
definition: Exact synonym.
definition: Fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software.
definition editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/20
has exact synonym: FULL_SYN
has exact synonym: Synonym with Source Data
label: has_exact_synonym
sub property of: alternative term

has_narrow_synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.
definition editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/19
label: has narrow synonym
sub property of: alternative term

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty
definition: Name space of the ontology.
comment: disease_ontology

has_related_synonym
type: AnnotationProperty
definition: An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.
definition: Has related synonym.
definition editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/21
label: has related synonym
sub property of: alternative term

has_synonym_type
type: AnnotationProperty

id
type: AnnotationProperty
definition: An identifier for an individual entity.
definition: An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity.

in subset
type: AnnotationProperty
definition: In subset.
definition: Used to associate the concept defining a particular terminology subset with concepts that belong to this subset.
has exact synonym: Concept_In_Subset
label: in_subset

shorthand
type: AnnotationProperty

ontology IUI
type: AnnotationProperty
editor preferred label: ontology instance unique identifier

ontology version IUI
type: AnnotationProperty
editor preferred label: ontology version instance unique identifier

comment
type: AnnotationProperty
definition: Comment.

rdfs:isDefinedBy
type: AnnotationProperty
definition: Is defined by.
OBO foundry unique label: is defined by

label
type: AnnotationProperty
editor preferred label: label
definition: A human readable name for this class.

see also
type: AnnotationProperty
has_obo_namespace: uberon
id: seeAlso
is metadata tag: true
shorthand: seeAlso

has exact match
type: AnnotationProperty
definition: A skos concept mapping used to link two concepts, indicating a high degree of confidence that the concepts can be used interchangeably.

depicted by
type: AnnotationProperty
has_obo_namespace: uberon
id: depicted_by
is metadata tag: true
shorthand: depicted_by

CI_ChemClass
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
code: C26
imported from: NDF-RT.owl

CI_MoA
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Cellular or Molecular Interactions [MoA]
type: NamedIndividual
code: C30
imported from: NDF-RT.owl

CI_PE
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Physiological Effects [PE]
type: NamedIndividual
code: C22
imported from: NDF-RT.owl

CI_with
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
code: C36
imported from: NDF-RT.owl

has_Ingredient
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Chemical Ingredients [Chemical/Ingredient]
code: C24
imported from: NDF-RT.owl

has_MoA
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Cellular or Molecular Interactions [MoA]
code: C28
imported from: NDF-RT.owl

has_PE
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Physiological Effects [PE]
code: C20
imported from: NDF-RT.owl

has_PK
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Clinical Kinetics [PK]
code: C32
imported from: NDF-RT.owl

may_prevent
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Diseases, Manifestations or Physiologic States [Disease/Finding]
code: C38
imported from: NDF-RT.owl

may_treat
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Diseases, Manifestations or Physiologic States [Disease/Finding]
code: C34
imported from: NDF-RT.owl

site_of_metabolism
type: ObjectProperty
domain: Pharmaceutical Preparations
range: Clinical Kinetics [PK]
code: C50
imported from: NDF-RT.owl

part of
type: ObjectProperty
equivalent property:
  inverse of: has part
sub property of: overlaps
sub property of: topObjectProperty
inverse of: has part
type: TransitiveProperty
domain: entity
range: entity
editor preferred label: is part of
example of usage: my brain is part of my body (continuant parthood, two material entities)
example of usage: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
example of usage: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
editor note: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
alternative term: part of
alternative term: part_of
imported from: BFO
imported from: apollo sv.owl
imported from: dron.owl
imported from: envo.owl
imported from: obi.owl
imported from: pr.owl
imported from: ro.owl
imported from: vo.owl
temporal interpretation: RO_0001901
is homeomorphic for: continuant
is homeomorphic for: occurrent
is homeomorphic for: independent continuant
is homeomorphic for: realizable entity
is homeomorphic for: quality
is homeomorphic for: specifically dependent continuant
is homeomorphic for: generically dependent continuant
database_cross_reference: BFO:0000050
has_obo_namespace: protein
id: part_of
in subset: valid for go annotation extension
in subset: valid for go gp2term
in subset: valid for go ontology
in subset: valid for gocam
shorthand: part_of
label: is part of
label: part_of

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
type: ReflexiveProperty
editor preferred label: has part
example of usage: my body has part my brain (continuant parthood, two material entities)
example of usage: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
example of usage: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
editor note: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
alternative term: has_part
imported from: BFO
imported from: apollo sv.owl
imported from: chebi.owl
imported from: dron.owl
imported from: envo.owl
imported from: obcs.owl
imported from: obi.owl
imported from: ogg.owl
imported from: pr.owl
imported from: ro.owl
imported from: vo.owl
temporal interpretation: RO_0001901
database_cross_reference: BFO:0000051
has_obo_namespace: chebi_ontology
has_obo_namespace: protein
id: has_part
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
is cyclic: false
shorthand: has_part
label: has_part

inheres in at all times
type: ObjectProperty
sub property of: specifically depends on at all times
domain: specifically dependent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
BFO OWL specification label: inheres-in_at
BFO CLIF specification label: inheresInAt
definition: b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'inheres in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'inheres in@en(x,y,t)'.
editor note: BFO 2 Reference: Inherence is a subrelation of s-depends_on which holds between a dependent continuant and an independent continuant that is not a spatial region. Since dependent continuants cannot migrate from one independent continuant bearer to another, it follows that if b s-depends_on independent continuant c at some time, then b s-depends_on c at all times at which a exists. Inherence is in this sense redundantly time-indexed.For example, consider the particular instance of openness inhering in my mouth at t as I prepare to take a bite out of a donut, followed by a closedness at t+1 when I bite the donut and start chewing. The openness instance is then shortlived, and to say that it s-depends_on my mouth at all times at which this openness exists, means: at all times during this short life. Every time you make a fist, you make a new (instance of the universal) fist. (Every time your hand has the fist-shaped quality, there is created a new instance of the universal fist-shaped quality.)
editor note: BFO2 Reference: independent continuant that is not a spatial region
editor note: BFO2 Reference: specifically dependent continuant
imported from: ogg.owl
has associated axiom(fol): (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002]

is_bearer_of
type: ObjectProperty
sub property of: topObjectProperty
type: TransitiveProperty
alternative term: bearer of
alternative term: bearer_of
imported from: dron.owl
imported from: http://purl.obolibrary.org/obo/omrse.owl
label: is bearer of

realized in
type: ObjectProperty
sub property of: topObjectProperty
inverse of: realizes
domain: realizable entity
range: process
editor preferred label: realized in
example of usage: this disease is realized in this disease course
example of usage: this fragility is realized in this shattering
example of usage: this investigator role is realized in this investigation
alternative term: is realized by
alternative term: realized_in
imported from: dron.owl
imported from: obi.owl
imported from: vo.owl
imported from: http://purl.obolibrary.org/obo/ro.owl
elucidation: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

realizes
type: ObjectProperty
domain: process
range: realizable entity
editor preferred label: realizes
example of usage: this disease course realizes this disease
example of usage: this investigation realizes this investigator role
example of usage: this shattering realizes this fragility
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl
elucidation: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

concretized by at some time
type: ObjectProperty
inverse of: concretizes at some time
domain: generically dependent continuant
range: specifically dependent continuant
BFO OWL specification label: concretized-by_st
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a piece of software by installing it in your computer
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
example of usage: [copied from inverse property 'concretizes at some time'] you may concretize a poem as a pattern of memory traces in your head
editor note: [copied from inverse property 'concretizes at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
imported from: ogg.owl
elucidation: [copied from inverse property 'concretizes at some time'] b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])

concretizes at some time
type: ObjectProperty
domain: specifically dependent continuant
range: generically dependent continuant
BFO OWL specification label: concretizes_st
BFO CLIF specification label: concretizesAt
example of usage: You may concretize a piece of software by installing it in your computer
example of usage: You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
example of usage: you may concretize a poem as a pattern of memory traces in your head
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
imported from: ogg.owl
elucidation: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has associated axiom(nl): if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
has associated axiom(fol): (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
has associated axiom(fol): (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: occurrent
range: occurrent
editor preferred label: preceded by
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
editor note: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
alternative term: is preceded by
alternative term: preceded_by
imported from: obi.owl
imported from: ro.owl
Source: http://www.obofoundry.org/ro/#OBO_REL:preceded_by
in subset: ro-eco

precedes
type: ObjectProperty
sub property of: temporal relation
type: TransitiveProperty
domain: occurrent
range: occurrent
editor preferred label: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
imported from: obi.owl
imported from: ro.owl
in subset: ro-eco

occurs in
type: ObjectProperty
editor preferred label: occurs in
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
alternative term: occurs_in
alternative term: unfolds in
alternative term: unfolds_in
imported from: ro.owl
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant

specifically depends on at all times
type: ObjectProperty
sub property of: specifically depends on at some time
BFO OWL specification label: s-depends-on_at
BFO CLIF specification label: specificallyDependsOn
example of usage: A pain s-depends_on the organism that is experiencing the pain
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
example of usage: a shape s-depends_on the shaped object
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'specifically depends on at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'specifically depends on@en(x,y,t)'.
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
imported from: ogg.owl
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]

has granular part
type: ObjectProperty
sub property of: has part
inverse of: is granular part of
alternative term: has_granular_part
imported from: dron.owl

is granular part of
type: ObjectProperty
sub property of: part of
domain: material entity
range: material entity
alternative term: granular part of
alternative term: granular_part_of
imported from: dron.owl

occupies spatial region at some time
type: ObjectProperty
inverse of: has spatial occupant at some time
domain: independent continuant
range: spatial region
BFO OWL specification label: located-at-r_st
BFO CLIF specification label: occupiesSpatialRegionAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
editor note: BFO2 Reference: independent continuant
editor note: BFO2 Reference: spatial region
imported from: ogg.owl
elucidation: b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])
has associated axiom(nl): every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002])
has associated axiom(nl): if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001])
has associated axiom(fol): (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002]
has associated axiom(fol): (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002]
has associated axiom(fol): (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001]

exists at
type: ObjectProperty
inverse of: during which exists
domain: entity
range: temporal region
BFO OWL specification label: exists-at
BFO CLIF specification label: existsAt
editor note: BFO2 Reference: entity
editor note: BFO2 Reference: temporal region
imported from: ogg.owl
elucidation: b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])

has occurrent part
type: ObjectProperty
inverse of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-has-part
BFO CLIF specification label: hasOccurrentPart
example of usage: [copied from inverse property 'part of occurrent'] Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: [copied from inverse property 'part of occurrent'] The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
example of usage: [copied from inverse property 'part of occurrent'] the first set of the tennis match occurrent_part_of the tennis match.
definition: b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
editor note: [copied from inverse property 'part of occurrent'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of occurrent'] BFO2 Reference: occurrent
imported from: ogg.owl
elucidation: [copied from inverse property 'part of occurrent'] b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has associated axiom(fol): (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001]

has proper occurrent part
type: ObjectProperty
sub property of: has occurrent part
inverse of: proper part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-has-ppart
BFO CLIF specification label: hasProperOccurrentPart
definition: [copied from inverse property 'proper part of occurrent'] b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
definition: b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001
imported from: ogg.owl

has spatial occupant at some time
type: ObjectProperty
domain: spatial region
range: independent continuant
BFO OWL specification label: r-location-of_st
editor note: [copied from inverse property 'occupies spatial region at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: independent continuant
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: spatial region
imported from: ogg.owl
elucidation: [copied from inverse property 'occupies spatial region at some time'] b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])

has specific dependent at some time
type: ObjectProperty
inverse of: specifically depends on at some time
domain: Class
  union of: process
  union of: specifically dependent continuant
  union of: Class
    intersection of: independent continuant
    intersection of: Class
      complement of: spatial region
range: Class
  union of: process
  union of: specifically dependent continuant
BFO OWL specification label: has-s-dep_st
example of usage: [copied from inverse property 'specifically depends on at some time'] A pain s-depends_on the organism that is experiencing the pain
example of usage: [copied from inverse property 'specifically depends on at some time'] a gait s-depends_on the walking object. (All at some specific time.)
example of usage: [copied from inverse property 'specifically depends on at some time'] a shape s-depends_on the shaped object
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: [copied from inverse property 'specifically depends on at some time'] the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: [copied from inverse property 'specifically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: [copied from inverse property 'specifically depends on at some time'] BFO2 Reference: specifically dependent continuant\; process; process boundary
imported from: ogg.owl
elucidation: [copied from inverse property 'specifically depends on at some time'] To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64

has spatiotemporal occupant
type: ObjectProperty
inverse of: occupies spatiotemporal region
domain: spatiotemporal region
range: occurrent
BFO OWL specification label: occupied-by
editor note: [copied from inverse property 'occupies spatiotemporal region'] BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
imported from: ogg.owl
elucidation: [copied from inverse property 'occupies spatiotemporal region'] p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])

occupies spatiotemporal region
type: ObjectProperty
domain: occurrent
range: spatiotemporal region
BFO OWL specification label: occupies
BFO CLIF specification label: occupiesSpatiotemporalRegion
editor note: BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
imported from: ogg.owl
elucidation: p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])

part of occurrent
type: ObjectProperty
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-part-of
BFO CLIF specification label: occurrentPartOf
example of usage: Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
example of usage: the first set of the tennis match occurrent_part_of the tennis match.
definition: [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: occurrent
imported from: ogg.owl
elucidation: b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has associated axiom(nl): occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001])
has associated axiom(nl): occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002])
has associated axiom(nl): occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001])
has associated axiom(nl): occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001])
has associated axiom(nl): occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001])
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001]
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001]
has associated axiom(fol): (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001]
has associated axiom(fol): (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002]

proper part of occurrent
type: ObjectProperty
sub property of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-ppart-of
BFO CLIF specification label: properOccurrentPartOf
definition: [copied from inverse property 'has proper occurrent part'] b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001
definition: b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
imported from: ogg.owl
has associated axiom(fol): (iff (properOccurrentPartOf a b) (and (occurrentPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [005-001]

temporal part of
type: ObjectProperty
sub property of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: t-part-of
BFO CLIF specification label: temporalPartOf
example of usage: the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life
example of usage: the process boundary which separates the 3rd and 4th years of your life.
example of usage: your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating
definition: b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
definition: b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])
imported from: ogg.owl
has associated axiom(nl): if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002])
has associated axiom(fol): (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002]
has associated axiom(fol): (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001]
has associated axiom(fol): (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003]

projects onto spatial region at some time
type: ObjectProperty
inverse of: spatial projection of spatiotemporal at some time
domain: spatiotemporal region
range: spatial region
BFO OWL specification label: st-projects-onto-s_st
imported from: ogg.owl

spatial projection of spatiotemporal at some time
type: ObjectProperty
domain: spatial region
range: spatiotemporal region
BFO OWL specification label: s-projection-of-st_st
imported from: ogg.owl

projects onto temporal region
type: ObjectProperty
sub property of: exists at
inverse of: temporal projection of spatiotemporal
domain: spatiotemporal region
range: temporal region
BFO OWL specification label: st-projects-onto-t
imported from: ogg.owl

temporal projection of spatiotemporal
type: ObjectProperty
sub property of: during which exists
domain: temporal region
range: spatiotemporal region
BFO OWL specification label: t-projection-of-st
imported from: ogg.owl

occupies temporal region
type: ObjectProperty
sub property of: exists at
inverse of: has temporal occupant
domain: occurrent
range: temporal region
BFO OWL specification label: spans
BFO CLIF specification label: occupiesTemporalRegion
imported from: ogg.owl
elucidation: p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])

has temporal occupant
type: ObjectProperty
sub property of: during which exists
domain: temporal region
range: occurrent
BFO OWL specification label: span-of
BFO CLIF specification label: spanOf
imported from: ogg.owl
elucidation: [copied from inverse property 'occupies temporal region'] p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])

during which exists
type: ObjectProperty
domain: temporal region
range: entity
BFO OWL specification label: during-which-exists
editor note: [copied from inverse property 'exists at'] BFO2 Reference: entity
editor note: [copied from inverse property 'exists at'] BFO2 Reference: temporal region
imported from: ogg.owl
elucidation: [copied from inverse property 'exists at'] b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])

bearer of at all times
type: ObjectProperty
sub property of: has specific dependent at all times
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: specifically dependent continuant
BFO OWL specification label: bearer-of_at
BFO CLIF specification label: bearerOfAt
definition: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'bearer of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'bearer of@en(x,y,t)'.
editor note: BFO2 Reference: independent continuant that is not a spatial region
editor note: BFO2 Reference: specifically dependent continuant
imported from: ogg.owl
has associated axiom(fol): (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]

has disposition at all times
type: ObjectProperty
sub property of: bearer of at all times
BFO OWL specification label: has-d_at
BFO CLIF specification label: hasDispositionAt
definition: a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has disposition at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has disposition@en(x,y,t)'.
imported from: ogg.owl
has associated axiom(fol): (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001]

has specific dependent at all times
type: ObjectProperty
sub property of: has specific dependent at some time
BFO OWL specification label: has-s-dep_at
imported from: ogg.owl

specifically depends on at some time
type: ObjectProperty
domain: Class
  union of: process
  union of: specifically dependent continuant
range: Class
  union of: process
  union of: specifically dependent continuant
  union of: Class
    intersection of: independent continuant
    intersection of: Class
      complement of: spatial region
BFO OWL specification label: s-depends-on_st
BFO CLIF specification label: specificallyDependsOn
example of usage: A pain s-depends_on the organism that is experiencing the pain
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
example of usage: a shape s-depends_on the shaped object
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
imported from: ogg.owl
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]

part of continuant at some time
type: ObjectProperty
inverse of: has continuant part at some time
domain: continuant
range: continuant
BFO OWL specification label: c-part-of_st
BFO CLIF specification label: continuantPartOfAt
example of usage: Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
editor note: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: continuant
editor note: BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
editor note: [copied from inverse property 'has continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
imported from: ogg.owl
elucidation: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(nl): continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has associated axiom(nl): continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has associated axiom(nl): continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has associated axiom(nl): continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has associated axiom(nl): continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has associated axiom(nl): if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
has associated axiom(fol): (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
has associated axiom(fol): (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
has associated axiom(fol): (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]

has continuant part at some time
type: ObjectProperty
domain: continuant
range: continuant
BFO OWL specification label: c-has-part_st
BFO CLIF specification label: hasContinuantPartAt
example of usage: [copied from inverse property 'part of continuant at some time'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: [copied from inverse property 'part of continuant at some time'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
editor note: [copied from inverse property 'part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuant
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
imported from: ogg.owl
elucidation: [copied from inverse property 'part of continuant at some time'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(fol): (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]

has continuant part at all times that part exists
type: ObjectProperty
sub property of: has continuant part at some time
type: TransitiveProperty
domain: continuant
range: continuant
BFO OWL specification label: c-has-part-object_at
example of usage: [copied from inverse property 'part of continuant at all times'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: [copied from inverse property 'part of continuant at all times'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
editor note: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
editor note: [copied from inverse property 'part of continuant at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuant
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
imported from: ogg.owl
elucidation: [copied from inverse property 'part of continuant at all times'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])

is host of
type: ObjectProperty

treatment for
type: ObjectProperty
definition: An object property that represents a relation between a material entity (e.g., drug or respirator) and a disease process where a drug is effective in treating a host against the disease process.
definition editor: Oliver He
comment: This term can be changed to the RO term 'is substance that treats' (RO_0002606). So it may be obsolete.

has active ingredient
type: ObjectProperty
definition: An object property that represents a relation between a drug and a chemical entity that is the active ingredient of the drug
definition editor: Oliver He, Yingtong Liu
definition source: https://en.wikipedia.org/wiki/Active_ingredient

EUA-authorized use at
type: ObjectProperty
sub property of: topObjectProperty
domain: CIDO_0000454
range: OBI_0000245
definition editor: Oliver He, Asiyah Lin
definition source: This relation is restricted to use for the LDTs authorization, means a diagnostic test deice is only authorized to use at the certain organization such as a company or hospital defined in the EUA authorization letter.

PCR kit detects gene
type: ObjectProperty
definition: A short-cut relation that represents a direct relationship between a PCR test kit and the target gene (or gene region) that the test kit is designed to run a PCR assay for amplifying and detecting the targeted gene or gene region.
definition editor: Asiyah Yu Lin, Oliver He

susceptible to adverse event
type: ObjectProperty
domain: material entity
range: OAE_0000001
definition: An object property that represents a relation between a material entity (such as a drug or chemical or vaccine) and an adverse event (AE) where the administration of the material entity is susceptible to the presence of the adverse event.
editor note: Note: This term needs to be moved to the OAE ontology.
definition editor: Oliver He, Yingtong Liu
comment: This term needs to be transferred to OAE

assay performed at
type: ObjectProperty
definition: An object property that represents a relation between an assay and an organization and the assay is performed at the organization such as a company or hospital
definition editor: Asiyah Yu Lin, Oliver He
alternative term: performed at

has susceptible host
type: ObjectProperty
example of usage: We can use the following axiom to represent the relation between a camel and MERS-CoV: MERS-COV: ‘has susceptible host’ some Camelus
definition: An object property that represents a relation between a microbe and an organism that serves as the host role and can host the survival of the microbe.
definition editor: Oliver He, Yang Wang

chemical degrades protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can degrate the protein.
definition editor: Oliver He, Jinyang Du

caused by infection with
type: ObjectProperty
definition: An object property that represents the relation between a disease process and a pathogen where the disease process is caused by the infection with the pathogen.
definition editor: Oliver He

has binding participant
type: ObjectProperty
sub property of: has_participant
definition: An object property between a binding process and a paritipant where the participant is one input of the binding process.
definition editor: Oliver He, Anthony Huffman

chemical has protein target
type: ObjectProperty
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Oliver He, Yingtong Liu
alternative term: chemical has protein target as modulator
definition source: https://en.wikipedia.org/wiki/Enzyme_modulator
comment: We make the relation 'chemical has protein target as modulator' as an alternative term here since the modulator is a very broad term that covers different topics including enzyme inhibitor/inducer, agonist, antagonist, etc.

chemical inhibits protein
type: ObjectProperty
sub property of: chemical has protein target
domain: chemical entity
range: PR_000000001
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme inhibitor. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Oliver He, Yingtong Liu
alternative term: chemical has protein target as inhibitor
definition source: https://en.wikipedia.org/wiki/Enzyme_inhibitor

chemical has protein target as antagonist
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an receptor antagonist. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Oliver He, Yingtong Liu
definition source: https://en.wikipedia.org/wiki/Receptor_antagonist

chemical has protein target as agonist
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an receptor agonist. Note that the chemical entity is usually an active compound of a corresponding drug. An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
definition editor: Oliver He, Yingtong Liu
definition source: https://en.wikipedia.org/wiki/Agonist

chemical binds protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an binder that chemically binds to the targeted protein. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Oliver He, Yingtong Liu
alternative term: chemical has protein target as binder

chemical induces protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme inducer. Note that the chemical entity is usually an active compound of a corresponding drug. An enzyme inducer is a type of chemical that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.
definition editor: Oliver He, Yingtong Liu
alternative term: chemical has protein target as inducer
definition source: https://en.wikipedia.org/wiki/Enzyme_inducer

drug has protein target
type: ObjectProperty
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein.
definition editor: Yingtong Liu, Oliver He

chemical has protein target as potentiator
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a potentiator. Note that the chemical entity is usually an active compound of a corresponding drug. In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug or protein regulator.
definition editor: Oliver He, Yingtong Liu
definition source: https://en.wikipedia.org/wiki/Potentiator

chemical activates protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme activator. Note that the chemical entity is usually an active compound of a corresponding drug. An enzyme inducer is a type of drug or chemcial that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.
definition editor: Oliver He, Yingtong Liu
alternative term: chemical has protein target as activator
definition source: https://en.wikipedia.org/wiki/Enzyme_activator

drug has protein target as agonist
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an receptor agonist. An agonist is a drug that binds to a receptor and activates the receptor to produce a biological response.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Agonist

drug has protein target as antagonist
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an receptor antagonist.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Receptor_antagonist

drug has protein target as binder
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an binder that chemically binds to the targeted protein.
definition editor: Yingtong Liu, Oliver He

drug has protein target as inducer
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme inducer. An enzyme inducer is a type of chemical that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Enzyme_inducer

drug has protein target as inhibitor
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme inhibitor.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Enzyme_inhibitor

drug has protein target as potentiator
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as a potentiator. In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug or protein regulator.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Potentiator

drug has protein target as activator
type: ObjectProperty
sub property of: drug has protein target
definition: An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme activator.An enzyme inducer is a type of drug or chemcial that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.
definition editor: Yingtong Liu, Oliver He
definition source: https://en.wikipedia.org/wiki/Enzyme_activator

chemical effective against virus
type: ObjectProperty
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection
definition editor: Yingtong Liu, Oliver He

chemical inhibits in vivo replication of virus
type: ObjectProperty
sub property of: chemical effective in vivo against virus
sub property of: chemical inhibits replication of virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral replication in vivo
definition editor: Oliver He, Yingtong Liu

chemical effective in vitro against virus
type: ObjectProperty
sub property of: chemical effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vitro
definition editor: Oliver He, Yingtong Liu

chemical effective in vivo against virus
type: ObjectProperty
sub property of: chemical effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vivo
definition editor: Oliver He, Yingtong Liu

chemical inhibits in vivo invasion of virus
type: ObjectProperty
sub property of: chemical effective in vivo against virus
sub property of: chemical inhibits invasion of virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral invasion in vivo
definition editor: Oliver He, Yingtong Liu

chemical inhibits in vitro replication of virus
type: ObjectProperty
sub property of: chemical effective in vitro against virus
sub property of: chemical inhibits replication of virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral replication in vitro
definition editor: Oliver He, Yingtong Liu

chemical inhibits in vitro invasion of virus
type: ObjectProperty
sub property of: chemical effective in vitro against virus
sub property of: chemical inhibits invasion of virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral invasion in vitro
definition editor: Oliver He, Yingtong Liu

chemical modulates response against virus
type: ObjectProperty
sub property of: chemical effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against virual infection
definition editor: Oliver He, Yingtong Liu

chemical modulates response in vivo against virus
type: ObjectProperty
sub property of: chemical effective in vivo against virus
sub property of: chemical modulates response against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against viral infection in vivo
definition editor: Oliver He, Yingtong Liu

chemical modulates response in vitro against virus
type: ObjectProperty
sub property of: chemical effective in vitro against virus
sub property of: chemical modulates response against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against viral infection in vitro
definition editor: Oliver He, Yingtong Liu

chemical inhibits invasion of virus
type: ObjectProperty
sub property of: chemical effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against virual invasion
definition editor: Oliver He, Yingtong Liu

chemical inhibits replication of virus
type: ObjectProperty
sub property of: chemical effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against virual replication
definition editor: Oliver He, Yingtong Liu

disease process susceptibly has phenotype
type: ObjectProperty
definition: An object property that represents a relation between a disease process and its susceptibility of inducing a phenotype outcome
definition editor: Oliver He, Yang Wang

drug effective against virus
type: ObjectProperty
definition: An object property that represents a relation between a drug and a virus where the drug has an effective role against viral infection
definition editor: Yingtong Liu, Oliver He

drug effective in vivo against virus
type: ObjectProperty
sub property of: drug effective against virus
definition: An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vivo
definition editor: Yingtong Liu, Oliver He

susceptibly occurs in
type: ObjectProperty
domain: process
range: material entity
example of usage: A COVID-19 disease process susceptibly occurs in the kidney.
definition: An object property that represents a relation between a process and a material entity (particularly an organism, anatomical entity, or cell) in which the process has a susceptible disposition to occur.
definition editor: Oliver He, Anthony Huffman

capable of inhibiting activity of
type: ObjectProperty
sub property of: causally related to
domain: material entity
range: material entity
example of usage: drug camostat --> molecule TMPRSS2
definition: An object property between material entity a and b where a is capable of inhibiting the activity of b.
definition editor: Oliver He, Yingtong Liu

induces in vivo production of
type: ObjectProperty
sub property of: causally related to
definition editor: Oliver He, Yingtong Liu
comment: An object property between material entity a and b where a is capable of inducing the production of b in vivo.

capable of priming activity of
type: ObjectProperty
sub property of: causally related to
example of usage: TMPRSS2 is responsible for priming of the viral spike protein that entails cleavage of the spike protein at two potential sites, Arg685/Ser686 and Arg815/Ser816. doi: https://doi.org/10.1101/2020.04.21.052639.
definition: An object property between material entity a and b where a is capable of priming the activity of b
definition editor: Oliver He, Yingtong Liu

catalyzed by
type: ObjectProperty
sub property of: has input
domain: process
range: PR_000000001
definition: a subproperty of 'enabled by' that represents a relation between a process and an enzyme where a protein is catalyzed by the enzyme in a catalytic reaction
definition editor: Oliver He, Anthoney Huffman

disease induced by phenotype
type: ObjectProperty
sub property of: causal relationship with disease as subject
domain: OGMS_0000031
example of usage: ARDS --> cytokine storm
definition: A causal relationship with disease as subject that shows that the realization of the disease is caused by a phenotype.
definition editor: Oliver He

causal relation related to phenotype
type: ObjectProperty
sub property of: causally related to
definition editor: Oliver He

phenotype has causal agent
type: ObjectProperty
sub property of: causal relation related to phenotype
range: material entity
definition editor: Oliver He

disease susceptibly severe with comorbidity
type: ObjectProperty
example of usage: COVID-19 disease (process) --> hypertension
definition editor: Oliver He, Yang Wang
comment: An object property that represents a relation between a disease process and a phenotype comorbidity where the disease (e.g., COVID-19 disease process) with the comorbidity is likely to have more severe outcome.

causal process for agent
type: ObjectProperty
sub property of: causal relation between material entity and a process

process up-regulates agent
type: ObjectProperty
sub property of: causal process for agent

variant of
type: ObjectProperty
sub property of: part of
definition: An object property that represents a relation between a molecular variant and a gene or protein where the variant derives from the gene or protein
definition editor: Oliver He

process capable of inducing phenotype
type: ObjectProperty
sub property of: causal relation related to phenotype
domain: process
definition: a causal relation between a process and a phenotype where the process is capable of inducing the phenotype.
definition editor: Oliver He

agent capable of inducing phenotype
type: ObjectProperty
sub property of: causal relation related to phenotype
domain: material entity
definition: a causal relation between a material entity and a phenotype where the material agent is capable of inducing the phenotype.
definition editor: Oliver He

has ligand
type: ObjectProperty
sub property of: has_participant
definition: A subproperty of 'has participant' that represents a relation between a process and a participant where the participant has the ligand role.
definition editor: Oliver He, Yingtong Liu, Peiling Tan

has receptor
type: ObjectProperty
sub property of: has_participant
definition: A subproperty of 'has participant' that represents a relation between a process and a participant where the participant has the receptor role.
definition editor: Oliver He, Yingtong Liu, Peiling Tan

has characteristic AA variant
type: ObjectProperty
sub property of: has AA variant
inverse of: is characteristic AA variant of
definition: An object property that defines a relation between a microbe variant and an AA variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one.
definition editor: Anthony Huffman, Oliver He
comment: An AA variant represents not only an amino acid (AA), but also a record of change from a previous AA to a new one. Therefore, instead of using 'has part', we generate this new property to represent the history of AA mutation.

organism susceptibly has up-regulated gene
type: ObjectProperty
inverse of: gene susceptibly up-regulated in organism
domain: OBI_0100026
range: OGG_0000000002
definition: An object property that represents a relation between an organism and a gene where the organism is susceptible to have an up-regulation of the expression of the gene.
definition editor: Oliver He, Anthony Huffman

gene susceptibly up-regulated in organism
type: ObjectProperty
definition: An object property that represents a relation between a gene and an organism where the gene is susceptibly up-regulated in the organism.
definition editor: Anthony Huffman, Oliver He

homologous epitope of
type: ObjectProperty
type: SymmetricProperty
definition: An object property that represents a relation between two epitopes X and Y where X is an homologous epitope of Y.
definition editor: Anthony Huffman, Oliver He

pathway susceptibly regulated in
type: ObjectProperty
sub property of: topObjectProperty
definition: An object property that represents a relation between a pathway (biological process) and a process in which the pathway is susceptibly to differential regulation in the process.
creator: Anthony Huffman, Yongqun 'Oliver' He

pathway susceptibly up-regulated in
type: ObjectProperty
sub property of: pathway susceptibly regulated in
creator: An object property that represents a relation between a pathway (biological process) and a process in which the pathway is susceptibly to differential up-regulation in the process.
creator: Anthony Huffman, Yongqun 'Oliver' He

binding to receptor
type: ObjectProperty
definition: An object property that represents a relation between a molecule and a receptor of the molecule where the molecule binds physically to the receptor.
definition editor: Anthony Huffman, Oliver He

pathway susceptibly down-regulated in
type: ObjectProperty
sub property of: pathway susceptibly regulated in
creator: An object property that represents a relation between a pathway (biological process) and a process in which the pathway is susceptibly to differential down-regulation in the process.
creator: Anthony Huffman, Yongqun 'Oliver' He

interactive relatoin between material entities
type: ObjectProperty
sub property of: obsolete related via dependence to

capable of binding to
type: ObjectProperty
sub property of: interactive relatoin between material entities

susceptible to infection of
type: ObjectProperty

susceptible to lethal infection of
type: ObjectProperty
sub property of: susceptible to infection of

has genetic mutation
type: ObjectProperty

chemical modulates protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a modulator. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Zalan Shah, Ashley Yan, Oliver He
alternative term: chemical has protein target as modulator

chemical has protein target as negative modulator
type: ObjectProperty
sub property of: chemical modulates protein
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a negative modulator. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Zalan Shah, Ashely Yan, Oliver He

has epitope cross-reactivity
type: ObjectProperty
type: TransitiveProperty
definition: A relation between two chemical entities X and Y such that if a portion of X is an epitope that binds to some antigen, there is also a portion of Y that is also an epitope which will bind to the same antigen.
creator: Anthony Huffman

chemical stimulates protein
type: ObjectProperty
sub property of: chemical has protein target
definition: An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a stimulator. Note that the chemical entity is usually an active compound of a corresponding drug.
definition editor: Zalan Shah, Ashley Yan, Oliver He
alternative term: chemical has protein target as stimulator

secreted from
type: ObjectProperty
domain: material entity
range: material entity
definition: An object property that represents a relation between a material entity (e.g., gene or protein) that is secreted from another material entity (e.g., cell).
definition editor: Oliver He

has motivation
type: ObjectProperty
range: CIDO_0000434
definition editor: Oliver He
alternative term: An object property that represents a relation between an entity and a motivation in which the entity has the motivation.

is AA variant of
type: ObjectProperty
definition editor: Anthony Huffman, Oliver He
comment: An object property that defines a relation between an AA variant and a microbe variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one.

has AA variant
type: ObjectProperty

has AA mutation
type: ObjectProperty

is AA mutation of
type: ObjectProperty
definition editor: An object property that defines a relation between a microbe variant and an AA mutation where the microbe (like SARS_CoV-2) variant has the AA mutation such that the microbe variant has an AA change. This is used over AA variant for deletions or nonsense mutations.
definition editor: Anthony Huffman, Oliver He

has characteristic AA mutation
type: ObjectProperty
sub property of: has AA mutation
inverse of: is characteristic AA mutation of
definition: An object property that defines a relation between a microbe variant and an AA mutation where the microbe (like SARS_CoV-2) variant has the AA mutation such that the microbe variant has an AA change that is used to identify a mircrobe variant. This is used over AA variant for deletions or nonsense mutations.
comment: An AA mutation represents the process of change from a previous AA to a new one. Therefore, instead of using 'has part', we generate this new property to represent the history of AA mutation. 'has AA mutation' is distinct from 'has AA variant' to account for mutations.

is characteristic AA variant of
type: ObjectProperty
sub property of: is AA variant of
definition editor: Anthony Huffman, Oliver He
comment: An object property that defines a relation between an AA variant and a microbe variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one and that such a variant is used to identify a microbe variant..

is characteristic AA mutation of
type: ObjectProperty
sub property of: is AA mutation of
definition: An object property that defines a relation between a microbe variant and an AA mutation where the microbe (like SARS_CoV-2) variant has the AA mutation such that the microbe variant has an AA change that is used to identify a microbe variant. This is used over AA variant for deletions or nonsense mutations.
definition editor: Anthony Huffman

has mutated from
type: ObjectProperty

device utilizes material
type: ObjectProperty

PCR detects gene
type: ObjectProperty
definition: A short-cut relation that represents a direct relationship between a PCR test and the target gene (or gene region) that the test is designed to amplify and detect the targeted gene or gene region.
definition editor: Asiyah Lin, Oliver He

susceptibly reduces vaccine efficacy
type: ObjectProperty
comment: Placeholder for VO

susceptibly alters process
type: ObjectProperty

susceptibly reduces process frequency
type: ObjectProperty
sub property of: susceptibly alters process
comment: Placeholder

susceptibly increases process frequency
type: ObjectProperty
sub property of: susceptibly alters process
comment: Placeholder

capable of infecting host
type: ObjectProperty
sub property of: causally related to
example of usage: SARS-CoV-2 is 'capable of infecting host' some human
definition: An object property that represents a relation between a microbe and a host organism where the microbe is capable of infecting the host organism.
definition editor: Muhui Ye, Oliver He

has measurement unit label
type: ObjectProperty
sub property of: has part
sub property of: topObjectProperty
type: FunctionalProperty
range: IAO_0000003
editor preferred label: has measurement unit label
definition: A relation between a value specification and its unit of measurement.
imported from: apollo sv.owl
imported from: dron.owl
imported from: http://purl.obolibrary.org/obo/obi.owl

is about
type: ObjectProperty
sub property of: topObjectProperty
domain: IAO_0000030
editor preferred label: is about
example of usage: This document is about information artifacts and their representations
has curation status: IAO_0000125
definition: A (currently) primitive relation that relates an information artifact to an entity.
definition: is_about is a (currently) primitive relation that relates an information artifact to an entity.
editor note: 7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of "mentions" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered "about" are predications - "The only person who knows the answer is sitting beside me" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic.
definition editor: person:Alan Ruttenberg
definition source: Smith, Ceusters, Ruttenberg, 2000 years of philosophy
imported from: apollo sv.owl
imported from: obcs.owl
imported from: obi.owl
imported from: http://purl.obolibrary.org/obo/iao.owl

denotes
type: ObjectProperty

has_specified_input
type: ObjectProperty
equivalent property:
  inverse of: is_specified_input_of
sub property of: has_participant
inverse of: is_specified_input_of
domain: OBI_0000011
editor preferred label: has_specified_input
example of usage: see is_input_of example_of_usage
has curation status: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
definition: The inverse property of is_specified_input_of
editor note: 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.
definition editor: PERSON: Alan Ruttenberg
definition editor: PERSON: Bjoern Peters
definition editor: PERSON: Larry Hunter
definition editor: PERSON: Melanie Coutot
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

is_specified_input_of
type: ObjectProperty
sub property of: participates in
range: OBI_0000011
editor preferred label: is_specified_input_of
example of usage: some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
has curation status: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
definition editor: Alan Ruttenberg
definition editor: PERSON:Bjoern Peters
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

has_specified_output
type: ObjectProperty
equivalent property:
  inverse of: is_specified_output_of
sub property of: has_participant
inverse of: is_specified_output_of
domain: OBI_0000011
editor preferred label: has_specified_output
has curation status: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
definition: The inverse property of is_specified_output_of
definition editor: PERSON: Alan Ruttenberg
definition editor: PERSON: Bjoern Peters
definition editor: PERSON: Larry Hunter
definition editor: PERSON: Melanie Courtot
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

is_manufactured_by
type: ObjectProperty
editor preferred label: is_manufactured_by
example of usage: http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities)
has curation status: IAO_0000123
definition: c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this.
definition editor: Alan Ruttenberg
definition editor: Liju Fan
alternative term: has_make
alternative term: has_manufacturer
imported from: obi.owl
imported from: vo.owl

is_specified_output_of
type: ObjectProperty
sub property of: participates in
range: OBI_0000011
editor preferred label: is_specified_output_of
has curation status: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
definition editor: Alan Ruttenberg
definition editor: PERSON:Bjoern Peters
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

obsolete_has_role
type: ObjectProperty
sub property of: ObsoleteProperty
editor preferred label: has_role
has curation status: IAO_0000122
definition: A relation between a continuant C and a role R. The reciprocal relation of role_of.
editor note: replaced by: http://purl.obolibrary.org/obo/BFO_0000087
definition editor: GROUP:OBI:<http://obi.sourceforge.net>
definition editor: PERSON:Chris Mungal
has obsolescence reason: IAO_0000228
imported from: obi.owl
deprecated: true

achieves_planned_objective
type: ObjectProperty
inverse of: objective_achieved_by
domain: OBI_0000011
range: IAO_0000005
editor preferred label: achieves_planned_objective
example of usage: A cell sorting process achieves the objective specification 'material separation objective'
has curation status: IAO_0000120
definition: This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
definition editor: BP, AR, PPPB branch
definition source: PPPB branch derived
curator note: modified according to email thread from 1/23/09 in accordince with DT and PPPB branch
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

has grain
type: ObjectProperty
sub property of: has part
editor preferred label: has grain
has curation status: IAO_0000120
definition: the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.
editor note: Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form
definition editor: PERSON: Alan Ruttenberg
definition source: PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349
imported from: obi.owl

objective_achieved_by
type: ObjectProperty
domain: IAO_0000005
range: OBI_0000011
editor preferred label: objective_achieved_by
has curation status: IAO_0000122
definition: This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
definition editor: OBI
definition source: OBI
imported from: obi.owl

has value specification
type: ObjectProperty
sub property of: has part
domain: IAO_0000030
range: OBI_0001933
editor preferred label: has value specification
has curation status: IAO_0000120
definition: A relation between an information content entity and a value specification that specifies its value.
definition editor: PERSON: James A. Overton
definition source: OBI
imported from: obi.owl

bound_to
type: ObjectProperty
domain: material entity
range: material entity
editor preferred label: bound_to
has curation status: IAO_0000123
definition: A relationship between two material entities that form a complex based on a selective, non-covalent interaction.
editor note: The definition of this term is modeled after the Chebi:50967 and GO:0005488 terms. Further alignment of the logical definitions with those ontologies will require agreement on the placement of GO:molecular function in BFO among other things. OBI will retire this term once such an alignment is achieved as 'bound to' is not in the primary OBI scope.
imported from: obi.owl

is genome of organism
type: ObjectProperty
sub property of: part of
definition: a 'part of continuant at some time' relation that incides a genome belongs to a organism.
definition editor: Yongqun He, Bin Zhao
imported from: ogg.owl

is gene of organism
type: ObjectProperty
sub property of: part of
domain: OGG_0000000002
range: OBI_0100026
definition: a relation between a gene and the organism where this gene belongs to the organism in nature. It does not include a foreign gene that is transferred to an organism by a genetic engineering method.
definition editor: Oliver He, Yue Liu
imported from: ogg.owl

has sex-specific susceptibility to
type: ObjectProperty
definition: An object property that represents a relation between a person with a biological sex and a process where the person has a specific susceptbility to a process
definition editor: Anthony Huffman, Oliver He
imported from: opmi.owl

has increased susceptibility compared to male to
type: ObjectProperty
sub property of: has sex-specific susceptibility to
definition: An object property that represents a relation between a person with a biological sex and a process where the person has an increased susceptbility to a process compared to corresponding male population
definition editor: Anthony Huffman, Oliver He
imported from: opmi.owl

has increased susceptibility compared to female to
type: ObjectProperty
sub property of: has sex-specific susceptibility to
example of usage: Male has increased susceptibility to death due to COVID-19 infection compared to female. Note that in this case, the male can mean one single male individual. however, the female here means the whole female population. It is reported that the ratio of deaths in COVID-19 infected males to females is 1·21:1 in high-income countries, but 2·8:1 in low-income countries (Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023692/).
definition: An object property that represents a relation between a person with a biological sex and a process where the person has an increased susceptbility to a process compared to corresponding female population
definition editor: Anthony Huffman, Oliver He
imported from: opmi.owl

has identifier
type: ObjectProperty

admitted from
type: ObjectProperty
example of usage: A patient was admitted to the hospital from home or a long-term care facility.
definition: An object property that represents a relation between a patient and a site from which the patient was admitted.
definition editor: Long Tran, Oliver He
definition source: http://ohdsi.github.io/CommonDataModel/cdm54.html#VISIT_OCCURRENCE
imported from: opmi.owl

discharged to
type: ObjectProperty
example of usage: After a visit, a person was discharged to home or a long-term care site. Typically this applies only to visits that have a length of stay of a day or more.
definition: An object property that represents a relation between a patient and a site to which the patient was discharged after a visit.
definition source: http://ohdsi.github.io/CommonDataModel/cdm54.html#VISIT_OCCURRENCE
imported from: opmi.owl

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
sub property of: topObjectProperty
inverse of: bearer of
type: FunctionalProperty
editor preferred label: inheres in
example of usage: this fragility inheres in this vase
example of usage: this fragility is a characteristic of this vase
example of usage: this red color inheres in this apple
example of usage: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
definition: a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence
editor note: A dependent inheres in its bearer at all times for which the dependent exists.
alternative term: inheres_in
imported from: dron.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl
temporal interpretation: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.
label: inheres in

bearer of
type: ObjectProperty
type: InverseFunctionalProperty
range: specifically dependent continuant
editor preferred label: bearer of
example of usage: this apple is bearer of this red color
example of usage: this vase is bearer of this fragility
definition: Inverse of characteristic_of
definition: a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence
editor note: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
alternative term: bearer_of
alternative term: is bearer of
imported from: envo.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl
temporal interpretation: RO_0001901
label: has characteristic

participates in
type: ObjectProperty
inverse of: has_participant
domain: continuant
range: occurrent
editor preferred label: participates in
example of usage: this blood clot participates in this blood coagulation
example of usage: this input material (or this output material) participates in this process
example of usage: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
alternative term: participates_in
imported from: obcs.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl

has_participant
type: ObjectProperty
sub property of: topObjectProperty
domain: occurrent
range: continuant
editor preferred label: has participant
example of usage: this blood coagulation has participant this blood clot
example of usage: this investigation has participant this investigator
example of usage: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
editor note: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
alternative term: has_participant
imported from: dron.owl
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl
imported from: http://purl.obolibrary.org/obo/ro.owl
Source: http://www.obofoundry.org/ro/#OBO_REL:has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant
label: has participant

concretizes
type: ObjectProperty
domain: specifically dependent continuant
range: generically dependent continuant
editor preferred label: concretizes
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.
imported from: obcs.owl
imported from: obi.owl
imported from: vo.owl

function of
type: ObjectProperty
sub property of: characteristic of
inverse of: has function
domain: function
example of usage: this catalysis function is a function of this enzyme
definition: a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
editor note: A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.
alternative term: function_of
alternative term: is function of
imported from: obi.owl

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
example of usage: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
editor note: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
alternative term: is role of
alternative term: role_of
imported from: ro.owl
imported from: vo.owl
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has function
type: ObjectProperty
sub property of: bearer of
domain: independent continuant
range: function
example of usage: this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)
definition: a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
editor note: A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.
alternative term: has_function
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl

has quality
type: ObjectProperty
sub property of: bearer of
range: quality
example of usage: this apple has quality this red color
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
editor note: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
alternative term: has_quality
imported from: envo.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl

has role
type: ObjectProperty
sub property of: bearer of
domain: independent continuant
range: role
example of usage: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
editor note: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
alternative term: has_role
imported from: chebi.owl
imported from: obi.owl
imported from: ro.owl
imported from: vo.owl
database_cross_reference: RO:0000087
has_obo_namespace: chebi_ontology
id: has_role
is cyclic: false
is transitive: false
shorthand: has_role

has disposition
type: ObjectProperty
definition: a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence
imported from: ro.owl

disposition of
type: ObjectProperty
definition: inverse of has disposition
imported from: ro.owl
in subset: RO_0002259
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

derives from
type: ObjectProperty
sub property of: topObjectProperty
inverse of: derives into
domain: independent continuant
range: independent continuant
editor preferred label: derives from
example of usage: this cell derives from this parent cell (cell division)
example of usage: this nucleus derives from this parent nucleus (nuclear division)
has curation status: IAO_0000125
definition: a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'.
alternative term: derives_from
imported from: obi.owl
imported from: ro.owl

derives into
type: ObjectProperty
example of usage: this parent cell derives into this cell (cell division)
example of usage: this parent nucleus derives into this nucleus (nuclear division)
has curation status: IAO_0000125
definition: a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'.
alternative term: derives_into
imported from: obi.owl

is allergic trigger for
type: ObjectProperty
sub property of: causes or contributes to condition
example of usage: penicillin (CHEBI:17334) is allergic trigger for penicillin allergy (DOID:0060520)
definition: A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
imported from: ro.owl

is autoimmune trigger for
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
imported from: ro.owl

has allergic trigger
type: ObjectProperty
sub property of: causes or contributes to condition
example of usage: penicillin allergy (DOID:0060520) has allergic trigger penicillin (CHEBI:17334)
definition: A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
imported from: ro.owl

has autoimmune trigger
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
imported from: ro.owl

located in
type: ObjectProperty
type: TransitiveProperty
domain: independent continuant
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: independent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
editor preferred label: located in
example of usage: my brain is located in my head
example of usage: this rat is located in this cage
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
editor note: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
alternative term: located_in
imported from: obi.owl
imported from: vo.owl
temporal interpretation: RO_0001901
Source: http://www.obofoundry.org/ro/#OBO_REL:located_in
source: http://www.obofoundry.org/ro/#OBO_REL:located_in

regulates in other organism
type: ObjectProperty
sub property of: causally upstream of or within
definition: x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
definition editor: David Osumi-Sutherland
imported from: ro.owl

occurrent part of
type: ObjectProperty
sub property of: part of
sub property of: causally upstream of or within
definition: A part of relation that applies only between occurrents.
imported from: ro.owl

has regulatory component activity
type: ObjectProperty
sub property of: has component activity
sub property of: regulated by
definition: A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:30:46Z

has negative regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: negatively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:31:01Z
comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.

has positive regulatory component activity
type: ObjectProperty
sub property of: has regulatory component activity
sub property of: positively regulated by
definition: A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:31:17Z
comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.

has necessary component activity
type: ObjectProperty
sub property of: has component activity
sub property of: positively regulated by
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:36:08Z
comment: A has necessary component activity B if A and B are GO molecular functions (GO_0003674), A has_component B and B is necessary for A. For example, ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity.

has component activity
type: ObjectProperty
sub property of: has component process
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:44:33Z
comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.

has component process
type: ObjectProperty
sub property of: has component
definition: w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
imported from: ro.owl
created_by: dos
creation_date: 2017-05-24T09:49:21Z

directly regulated by
type: ObjectProperty
sub property of: regulated by
imported from: ro.owl
created_by: dos
creation_date: 2017-09-17T13:52:24Z
comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.

directly negatively regulated by
type: ObjectProperty
sub property of: directly regulated by
definition: Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
imported from: ro.owl
created_by: dos
creation_date: 2017-09-17T13:52:38Z

directly positively regulated by
type: ObjectProperty
sub property of: directly regulated by
definition: Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
imported from: ro.owl
created_by: dos
creation_date: 2017-09-17T13:52:47Z

ends after
type: ObjectProperty
sub property of: temporal relation
type: TransitiveProperty
definition editor: David Osumi-Sutherland
imported from: ro.owl
in subset: ro-eco
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
definition editor: David Osumi-Sutherland
alternative term: starts_at_end_of
imported from: obi.owl
imported from: ro.owl
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

immediately precedes
type: ObjectProperty
sub property of: precedes
definition editor: David Osumi-Sutherland
alternative term: ends_at_start_of
alternative term: meets
imported from: obi.owl
imported from: ro.owl
is direct form of: precedes
in subset: ro-eco
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
has curation status: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
imported from: envo.owl
imported from: ro.owl
expand expression to: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
temporal interpretation: RO_0001901
in subset: valid for go annotation extension
in subset: valid for gocam
in subset: ro-eco

only in taxon
type: ObjectProperty
example of usage: lactation SubClassOf 'only in taxon' some 'Mammalia'
has curation status: IAO_0000125
definition: x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
editor note: The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria
definition editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/17921072
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20973947
imported from: ro.owl

spatially disjoint from
type: ObjectProperty
sub property of: mereotopologically related to
has curation status: IAO_0000125
definition: A is spatially_disjoint_from B if and only if they have no parts in common
editor note: There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom.
definition editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
curator note: Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy
imported from: envo.owl
expand expression to: BFO_0000051 exactly 0 (BFO_0000050 some ?Y)
temporal interpretation: RO_0001901
in subset: ro-eco

has component
type: ObjectProperty
sub property of: has part
has curation status: IAO_0000125
definition: w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
editor note: The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
curator note: For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
imported from: obi.owl
imported from: ro.owl
temporal interpretation: RO_0001901
in subset: ro-eco

has phenotype
type: ObjectProperty
sub property of: has phenotype or disease
has curation status: IAO_0000125
definition: A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).
definition editor: Chris Mungall
imported from: ro.owl
in subset: ro-eco

regulates
type: ObjectProperty
sub property of: causally upstream of
type: TransitiveProperty
definition: p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
definition editor: Chris Mungall
definition editor: David Hill
definition editor: Tanya Berardini
definition source: causal-relations
definition source: GO
curator note: Regulation precludes parthood; the regulatory process may not be within the regulated process.
imported from: ro.owl
OBO foundry unique label: regulates (processual)
elucidation: false
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

negatively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, negative effect
definition: p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: negatively regulates (process to process)
is negative form of: regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

positively regulates
type: ObjectProperty
sub property of: regulates
sub property of: causally upstream of, positive effect
type: TransitiveProperty
definition: p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: positively regulates (process to process)
is positive form of: regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

capable of
type: ObjectProperty
sub property of: capable of part of
example of usage: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
example of usage: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
definition editor: Chris Mungall
alternative term: has function realized in
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20123131
definition source: http://www.ncbi.nlm.nih.gov/pubmed/21208450
curator note: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
imported from: ro.owl
in subset: ro-eco

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
definition editor: Chris Mungall
alternative term: has function in
imported from: ro.owl

surrounded by
type: ObjectProperty
sub property of: adjacent to
has curation status: IAO_0000125
definition: x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
definition editor: Chris Mungall
imported from: envo.owl
temporal interpretation: RO_0001901

adjacent to
type: ObjectProperty
sub property of: spatially disjoint from
type: FunctionalProperty
example of usage: A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.
example of usage: The epidermis layer of a vertebrate is adjacent to the dermis.
example of usage: The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.
example of usage: The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.
has curation status: IAO_0000125
definition: x adjacent to y if and only if x and y share a boundary.
editor note: This relation acts as a join point with BSPO
definition editor: Chris Mungall
imported from: envo.owl
temporal interpretation: RO_0001901

temporal relation
type: ObjectProperty
range: occurrent
has curation status: IAO_0000125
editor note: move to BFO?
definition editor: Chris Mungall
definition source: Allen's interval algebra
definition source: Allen
curator note: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
imported from: obi.owl
imported from: ro.owl
source: https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit
in subset: ro-eco
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.
label: temporally related to

has input
type: ObjectProperty
has curation status: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
definition editor: Chris Mungall
alternative term: consumes
imported from: ro.owl
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

has output
type: ObjectProperty
has curation status: IAO_0000125
definition: p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
definition editor: Chris Mungall
alternative term: produces
imported from: ro.owl
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

has exposure receptor
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event.
definition source: ExO:0000001
imported from: ro.owl

has exposure stressor
type: ObjectProperty
sub property of: has exposure stimulus
definition: A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event.
definition source: ExO:0000000
imported from: ro.owl

has exposure route
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor
definition source: ExO:0000055
imported from: ro.owl

has exposure transport path
type: ObjectProperty
sub property of: related via exposure to
definition: A broad relationship between an exposure event or process and the course takes from the source to the target.
definition source: http://purl.obolibrary.org/obo/ExO_0000004
imported from: ro.owl

related via exposure to
type: ObjectProperty
sub property of: causally related to
definition: Any relationship between an exposure event or process and any other entity.
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving exposure events or processes.
imported from: ro.owl

acts upstream of
type: ObjectProperty
sub property of: acts upstream of or within
example of usage: A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
definition: c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
imported from: ro.owl
in subset: valid for go gp2term

acts upstream of or within
type: ObjectProperty
sub property of: causal agent in process
example of usage: A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
definition: c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
imported from: ro.owl
has_related_synonym: affects
in subset: valid for go gp2term

expresses
type: ObjectProperty
has curation status: IAO_0000125
definition: Inverse of 'expressed in'
definition editor: Chris Mungall
imported from: ro.owl

is treated by substance
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'is substance that treats'
imported from: ro.owl
creator: cjm
in subset: RO_0002259

causally upstream of, positive effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, positive effect
definition: p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
imported from: ro.owl
is positive form of: causally upstream of
creator: cjm
in subset: valid for go annotation extension
in subset: valid for gocam
comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y

causally upstream of, negative effect
type: ObjectProperty
sub property of: causally upstream of
sub property of: causally upstream of or within, negative effect
definition: p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
imported from: ro.owl
is negative form of: causally upstream of
creator: cjm
in subset: valid for go annotation extension
in subset: valid for gocam

has exposure stimulus
type: ObjectProperty
sub property of: related via exposure to
definition: A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.
imported from: ro.owl
contributor: Austin Meier
contributor: Chris Mungall
contributor: Marie Angelique Laporte
created_by: cjm
creation_date: 2017-06-05T17:35:04Z

characteristic of part of
type: ObjectProperty
sub property of: depends on
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
editor note: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
definition editor: https://orcid.org/0000-0002-6601-2165
alternative term: inheres in part of
definition source: http://www.ncbi.nlm.nih.gov/pubmed/20064205
imported from: ro.owl
imported from: vo.owl
temporal interpretation: RO_0001901

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
definition editor: Chris Mungall
curator note: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
imported from: envo.owl
imported from: ro.owl
temporal interpretation: RO_0001901

contributes to
type: ObjectProperty
sub property of: capable of part of
sub property of: part of structure that is capable of
example of usage: ATP citrate lyase (ACL) in Arabidopsis: it is a heterooctamer, composed of two types of subunits, ACLA and ACLB in a A(4)B(4) stoichiometry. Neither of the subunits expressed alone give ACL activity, but co-expression results in ACL activity. Both subunits contribute_to the ATP citrate lyase activity.
example of usage: Subunits of nuclear RNA polymerases: none of the individual subunits have RNA polymerase activity, yet all of these subunits contribute_to DNA-dependent RNA polymerase activity.
example of usage: eIF2: has three subunits (alpha, beta, gamma); one binds GTP; one binds RNA; the whole complex binds the ribosome (all three subunits are required for ribosome binding). So one subunit is annotated to GTP binding and one to RNA binding without qualifiers, and all three stand in the contributes_to relationship to "ribosome binding". And all three are part_of an eIF2 complex
editor note: We would like to say if and only if exists c', p' c part_of c' and c' capable_of p and c capable_of p' and p' part_of p then c contributes_to p However, this is not possible in OWL. We instead make this relation a sub-relation of the two chains, which gives us the inference in the one direction.
definition editor: Chris Mungall
curator note: In the context of the Gene Ontology, contributes_to may be used only with classes from the molecular function ontology.
imported from: ro.owl
in subset: valid for go gp2term

enables
type: ObjectProperty
sub property of: capable of
example of usage: a particular instances of akt-2 enables some instance of protein kinase activity
definition: c enables p iff c is capable of p and c acts to execute p.
definition editor: Chris Mungall
alternative term: catalyzes
alternative term: executes
alternative term: has
alternative term: is catalyzing
alternative term: is executing
curator note: This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.
imported from: ro.owl
in subset: valid for go gp2term

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
definition editor: Chris Mungall
curator note: This is a grouping relation that collects relations used for the purpose of connecting structure and function
imported from: ro.owl

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
definition editor: Chris Mungall
alternative term: false
imported from: ro.owl

involved in
type: ObjectProperty
sub property of: participates in
sub property of: involved in or involved in regulation of
definition: c involved_in p if and only if c enables some process p', and p' is part of p
definition editor: Chris Mungall
alternative term: actively involved in
alternative term: enables part of
imported from: ro.owl

regulated by
type: ObjectProperty
sub property of: causally downstream of or within
type: TransitiveProperty
definition: inverse of regulates
definition editor: Chris Mungall
imported from: ro.owl
OBO foundry unique label: regulated by (processual)
in subset: RO_0002259

negatively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of negatively regulates
definition editor: Chris Mungall
imported from: ro.owl
in subset: RO_0002259

positively regulated by
type: ObjectProperty
sub property of: regulated by
definition: inverse of positively regulates
definition editor: Chris Mungall
imported from: ro.owl
in subset: RO_0002259

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
imported from: obcs.owl
imported from: ro.owl

causally downstream of
type: ObjectProperty
sub property of: preceded by
sub property of: causally downstream of or within
has curation status: IAO_0000428
definition: inverse of upstream of
definition editor: Chris Mungall
imported from: ro.owl

immediately causally downstream of
type: ObjectProperty
sub property of: immediately preceded by
sub property of: causally downstream of
has curation status: IAO_0000428
definition editor: Chris Mungall
imported from: ro.owl

indirectly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: indirectly regulates
type: TransitiveProperty
definition: p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
definition editor: Chris Mungall
alternative term: indirectly activates
imported from: ro.owl
is indirect form of: positively regulates

indirectly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: indirectly regulates
type: TransitiveProperty
definition: p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
definition editor: Chris Mungall
alternative term: indirectly inhibits
imported from: ro.owl
is indirect form of: negatively regulates

causally related to
type: ObjectProperty
definition: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
editor note: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
definition editor: Chris Mungall
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
imported from: ro.owl

causally upstream of
type: ObjectProperty
sub property of: precedes
sub property of: causally upstream of or within
type: TransitiveProperty
definition: p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
definition editor: Chris Mungall
imported from: ro.owl
in subset: valid for go annotation extension
in subset: valid for gocam

immediately causally upstream of
type: ObjectProperty
sub property of: immediately precedes
sub property of: causally upstream of
definition: p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
definition editor: Chris Mungall
imported from: ro.owl
is direct form of: causally upstream of

provides input for
type: ObjectProperty
sub property of: immediately causally upstream of
sub property of: transitively provides input for
definition: p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c.
editor note: This is currently called 'directly provides input for' to be consistent with our terminology where we use 'direct' whenever two occurrents succeed one another directly. We may relabel this simply 'provides input for', as directness is implicit
definition editor: Chris Mungall
alternative term: directly provides input for
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: directly provides input for (process to process)

transitively provides input for
type: ObjectProperty
sub property of: causally upstream of or within, positive effect
type: TransitiveProperty
has curation status: IAO_0000428
definition: transitive form of directly_provides_input_for
definition editor: Chris Mungall
curator note: This is a grouping relation that should probably not be used in annotation. Consider instead the child relation 'provides input for'.
imported from: ro.owl
OBO foundry unique label: transitively provides input for (process to process)

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
editor note: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
definition editor: Chris Mungall
alternative term: influences (processual)
imported from: ro.owl
has_related_synonym: affects

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl
in subset: RO_0002259

involved in regulation of
type: ObjectProperty
sub property of: acts upstream of
sub property of: involved in or involved in regulation of
definition: c involved in regulation of p if c is involved in some p' and p' regulates some p
definition editor: Chris Mungall
imported from: ro.owl

involved in positive regulation of
type: ObjectProperty
sub property of: involved in regulation of
definition: c involved in regulation of p if c is involved in some p' and p' positively regulates some p
definition editor: Chris Mungall
imported from: ro.owl
is positive form of: involved in regulation of

involved in negative regulation of
type: ObjectProperty
sub property of: involved in regulation of
definition: c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
definition editor: Chris Mungall
imported from: ro.owl
is negative form of: involved in regulation of

involved in or involved in regulation of
type: ObjectProperty
sub property of: acts upstream of or within
sub property of: functionally related to
sub property of: causal agent in process
definition: c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
editor note: OWL does not allow defining object properties via a Union
definition editor: Chris Mungall
alternative term: involved in or reguates
imported from: ro.owl

interacts with
type: ObjectProperty
type: SymmetricProperty
definition: A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
editor note: This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
editor note: Considering relabeling as 'pairwise interacts with'
definition editor: Chris Mungall
curator note: Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.
imported from: ro.owl
has exact synonym: in pairwise interaction with
in subset: ro-eco

molecularly interacts with
type: ObjectProperty
sub property of: interacts with
type: SymmetricProperty
definition: An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
definition editor: Chris Mungall
alternative term: binds
alternative term: molecularly binds with
imported from: ro.owl

directly regulates activity of
type: ObjectProperty
sub property of: molecularly interacts with
sub property of: regulates activity of
definition: The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
definition editor: Chris Mungall
definition editor: Vasundra Touré
imported from: ro.owl
has exact synonym: molecularly controls

directly negatively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
definition: The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
definition editor: Chris Mungall
definition editor: Vasundra Touré
alternative term: directly inhibits
imported from: ro.owl
has exact synonym: molecularly decreases activity of

directly positively regulates activity of
type: ObjectProperty
sub property of: directly regulates activity of
definition: The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
definition editor: Chris Mungall
definition editor: Vasundra Touré
alternative term: directly activates
imported from: ro.owl
has exact synonym: molecularly increases activity of

composed primarily of
type: ObjectProperty
sub property of: has part
example of usage: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
definition editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/22293552
imported from: envo.owl
temporal interpretation: RO_0001901
in subset: ro-eco

existence starts during or after
type: ObjectProperty

existence ends during or before
type: ObjectProperty

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
definition source: causal-relations
imported from: ro.owl

causal relation between processes
type: ObjectProperty
sub property of: causally related to
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
definition editor: Chris Mungall
definition source: causal-relations
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
imported from: ro.owl

depends on
type: ObjectProperty
definition editor: https://orcid.org/0000-0002-6601-2165
imported from: ro.owl
imported from: vo.owl

causal relation between entities
type: ObjectProperty
sub property of: causally related to
editor note: The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
definition editor: Chris Mungall
definition source: causal-relations
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
imported from: ro.owl

determined by
type: ObjectProperty
sub property of: part of
sub property of: determined by part of
sub property of: causally influenced by
example of usage: A coral reef environment is determined by a particular coral reef
definition: s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s.
editor note: The label for this relation is probably too general for its restricted use, where the domain is a system. It may be relabeled in future
definition editor: Chris Mungall
definition source: http://www.ncbi.nlm.nih.gov/pubmed/24330602
imported from: ro.owl
OBO foundry unique label: determined by (system to material entity)
creator: Chris Mungall
creator: Pier Buttigieg
in subset: ro-eco

determines
type: ObjectProperty
sub property of: causally influences
definition: inverse of determined by
definition editor: Chris Mungall
imported from: ro.owl
OBO foundry unique label: determines (material entity to system)
in subset: RO_0002259
in subset: ro-eco

determined by part of
type: ObjectProperty
sub property of: overlaps
sub property of: causal relation between entities
definition: s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.
definition editor: Chris Mungall
imported from: ro.owl
in subset: ro-eco

causally influenced by
type: ObjectProperty
sub property of: causal relation between entities
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: causally influenced by (entity-centric)

causally influences
type: ObjectProperty
sub property of: causal relation between entities
definition: The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
definition editor: Chris Mungall
definition editor: Vasundra Touré
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: causally influences (entity-centric)

directly regulates
type: ObjectProperty
sub property of: regulates
sub property of: immediately causally upstream of
definition: p directly regulates q iff p is immediately causally upstream of q and p regulates q.
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: directly regulates (processual)
is direct form of: regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
example of usage: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
definition editor: Chris Mungall
imported from: ro.owl

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
editor note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
definition editor: Chris Mungall
definition source: causal-relations
imported from: ro.owl

capable of regulating
type: ObjectProperty
sub property of: causal agent in process
example of usage: pyrethroid -> growth
definition: Holds between c and p if and only if c is capable of some activity a, and a regulates p.
definition source: causal-relations
imported from: ro.owl

capable of negatively regulating
type: ObjectProperty
sub property of: capable of regulating
definition: Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
definition source: causal-relations
imported from: ro.owl

capable of positively regulating
type: ObjectProperty
sub property of: capable of regulating
example of usage: renin -> arteriolar smooth muscle contraction
definition: Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
definition source: causal-relations
imported from: ro.owl

capable of inhibiting or preventing pathological process
type: ObjectProperty
sub property of: capable of negatively regulating
example of usage: pazopanib -> pathological angiogenesis
definition: Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p.
alternative term: treats
definition source: causal-relations
curator note: The entity c may be a molecular entity with a drug role, or it could be some other entity used in a therapeutic context, such as a hyperbaric chamber.
imported from: ro.owl

capable of upregulating or causing pathological process
type: ObjectProperty
sub property of: capable of positively regulating
example of usage: benzene -> cancer [CHEBI]
definition: Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p.
alternative term: causes disease
definition source: causal-relations
imported from: ro.owl

is substance that treats
type: ObjectProperty
sub property of: capable of inhibiting or preventing pathological process
definition: c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d.
alternative term: treats
definition source: causal-relations
imported from: ro.owl

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
definition source: causal-relations
imported from: ro.owl

obsolete related via dependence to
type: ObjectProperty
definition: A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
imported from: ro.owl

directly positively regulates
type: ObjectProperty
sub property of: positively regulates
sub property of: directly regulates
definition: p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: directly positively regulates (process to process)
is positive form of: directly regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

directly negatively regulates
type: ObjectProperty
sub property of: negatively regulates
sub property of: directly regulates
definition: p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
definition source: causal-relations
imported from: ro.owl
OBO foundry unique label: directly negatively regulates (process to process)
is negative form of: directly regulates
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

represses expression of
type: ObjectProperty
sub property of: directly negatively regulates activity of
definition: Holds between entity A (a transcription factor) and a nucleic acid B if and only if A down-regulates the expression of B. The nucleic acid can be a gene or an mRNA.
definition editor: Vasundra Touré
imported from: ro.owl

increases expression of
type: ObjectProperty
sub property of: directly positively regulates activity of
definition: Holds between entity A (a transcription factor) and nucleic acid B if and only if A up-regulates the expression of B. The nucleic acid can be a gene or mRNA.
definition editor: Vasundra Touré
imported from: ro.owl

causes or contributes to condition
type: ObjectProperty
sub property of: causally related to
example of usage: The genetic variant 'NM_007294.3(BRCA1):c.110C>A (p.Thr37Lys)' casues or contributes to the disease 'familial breast-ovarian cancer'. An environment of exposure to arsenic causes or contributes to the phenotype of patchy skin hyperpigmentation, and the disease 'skin cancer'.
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition.
editor note: Note that relationships of phenotypes to organisms/strains that bear them, or diseases they are manifest in, should continue to use RO:0002200 ! 'has phenotype' and RO:0002201 ! 'phenotype of'.
imported from: ro.owl
comment: Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.

causes condition
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition.
imported from: ro.owl

contributes to condition
type: ObjectProperty
sub property of: causes or contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition.
imported from: ro.owl

contributes to severity of condition
type: ObjectProperty
sub property of: contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual.
alternative term: contributes to expressivity of condition
imported from: ro.owl

contributes to frequency of condition
type: ObjectProperty
sub property of: contributes to condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.
alternative term: contributes to penetrance of condition
imported from: ro.owl

ameliorates condition
type: ObjectProperty
sub property of: contributes to severity of condition
definition: A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.
alternative term: is preventative for condition
imported from: ro.owl
comment: Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.

exacerbates condition
type: ObjectProperty
sub property of: contributes to severity of condition
definition: A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.
imported from: ro.owl

condition ameliorated by
type: ObjectProperty
sub property of: causally related to
definition: A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity.
imported from: ro.owl

condition exacerbated by
type: ObjectProperty
sub property of: causally related to
definition: A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity.
imported from: ro.owl

condition has genetic basis in
type: ObjectProperty
sub property of: causally related to
curator note: Do not use this relation directly. It is intended as a grouping for a more specific relations
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:38:20Z

has material basis in gain of function germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:45:20Z

has material basis in loss of function germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:45:37Z

has material basis in germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:45:54Z

has material basis in somatic mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:46:07Z

has major susceptibility factor
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:46:26Z

has partial material basis in germline mutation in
type: ObjectProperty
sub property of: condition has genetic basis in
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:46:57Z

is genetic basis for condition
type: ObjectProperty
sub property of: is basis for realizable
curator note: Do not use this relation directly. It is intended as a grouping for a more specific relations
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:53:08Z

is causal gain of function germline mutation of in
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene in a germ cell provides a new function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:55:51Z

is causal loss of function germline mutation of in
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene in a germ cell impairs the function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:56:06Z

is causal germline mutation in
type: ObjectProperty
sub property of: causes condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:56:40Z

is causal somatic mutation in
type: ObjectProperty
sub property of: causes condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition but that cannot be passed on to offspring[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:57:07Z

is causal susceptibility factor for
type: ObjectProperty
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene predisposes to the development of a condition and that is necessary but not sufficient to develop the condition[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:57:43Z

is causal germline mutation partially giving rise to
type: ObjectProperty
sub property of: contributes to condition
sub property of: is genetic basis for condition
definition: Relates a gene to condition, such that a mutation in this gene partially contributes to the presentation of this condition[modified from orphanet].
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T02:58:43Z

realizable has basis in
type: ObjectProperty
sub property of: causally related to
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T03:20:01Z

is basis for realizable
type: ObjectProperty
sub property of: causally related to
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T03:20:29Z

disease has basis in
type: ObjectProperty
sub property of: realizable has basis in
sub property of: causal relationship with disease as subject
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T03:26:47Z

disease has basis in dysfunction of
type: ObjectProperty
sub property of: disease has basis in
definition: A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function.
imported from: ro.owl
OBO foundry unique label: disease has basis in dysfunction of (disease to anatomical structure)
created_by: cjm
creation_date: 2017-11-05T03:29:32Z

disease has basis in disruption of
type: ObjectProperty
sub property of: disease has basis in
definition: A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process.
imported from: ro.owl
OBO foundry unique label: disease has basis in disruption of (disease to process)
created_by: cjm
creation_date: 2017-11-05T03:37:52Z

disease has basis in feature
type: ObjectProperty
sub property of: has phenotype
sub property of: disease has basis in
definition: A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature.
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T03:46:07Z

causal relationship with disease as subject
type: ObjectProperty
sub property of: causally related to
sub property of: disease relationship
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all of which have a disease as the subject.
imported from: ro.owl
created_by: cjm
creation_date: 2017-11-05T03:50:54Z

disease causes disruption of
type: ObjectProperty
sub property of: causal relationship with disease as subject
definition: A relationship between a disease and a process where the disease process disrupts the execution of the process.
imported from: ro.owl
OBO foundry unique label: disease causes disruption of (disease to process)
created_by: cjm
creation_date: 2017-11-05T03:51:09Z

disease causes dysfunction of
type: ObjectProperty
sub property of: causal relationship with disease as subject
imported from: ro.owl
OBO foundry unique label: disease causes dysfunction of (disease to anatomical entity)
created_by: cjm
creation_date: 2017-11-05T03:58:20Z

realized in response to stimulus
type: ObjectProperty
sub property of: causally related to
definition: A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M.
imported from: ro.owl
created_by: cjm
creation_date: 2017-12-26T19:45:49Z

disease arises from alteration in structure
type: ObjectProperty
sub property of: disease has basis in
definition: A relationship between a disease and an anatomical structure where the material basis of the disease is some pathological change in the structure. Anatomical structure includes cellular and sub-cellular entities, such as chromosome and organelles.
imported from: ro.owl
created_by: cjm
creation_date: 2017-12-26T19:58:44Z

acts upstream of or within, positive effect
type: ObjectProperty
sub property of: acts upstream of or within
imported from: ro.owl
is positive form of: acts upstream of or within
created_by: cjm
creation_date: 2018-01-26T23:49:30Z
in subset: valid for go gp2term

acts upstream of or within, negative effect
type: ObjectProperty
sub property of: acts upstream of or within
imported from: ro.owl
is negative form of: acts upstream of or within
created_by: cjm
creation_date: 2018-01-26T23:49:51Z
in subset: valid for go gp2term

acts upstream of, positive effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, positive effect
definition: c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
imported from: ro.owl
is positive form of: acts upstream of
created_by: cjm
creation_date: 2018-01-26T23:53:14Z
in subset: valid for go gp2term

acts upstream of, negative effect
type: ObjectProperty
sub property of: acts upstream of
sub property of: acts upstream of or within, negative effect
definition: c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
imported from: ro.owl
is negative form of: acts upstream of
created_by: cjm
creation_date: 2018-01-26T23:53:22Z
in subset: valid for go gp2term

causally upstream of or within, negative effect
type: ObjectProperty
sub property of: causally upstream of or within
imported from: ro.owl
is negative form of: causally upstream of or within
created_by: cjm
creation_date: 2018-03-13T23:55:05Z

causally upstream of or within, positive effect
type: ObjectProperty
sub property of: causally upstream of or within
imported from: ro.owl
is positive form of: causally upstream of or within
created_by: cjm
creation_date: 2018-03-13T23:55:19Z

realized in response to
type: ObjectProperty
sub property of: causally related to
example of usage: A drought sensitivity trait that inheres in a whole plant is realized in a systemic response process in response to exposure to drought conditions.
example of usage: An inflammatory disease that is realized in response to an inflammatory process occurring in the gut (which is itself the realization of a process realized in response to harmful stimuli in the mucosal lining of th gut)
example of usage: Environmental polymorphism in butterflies: These butterflies have a 'responsivity to day length trait' that is realized in response to the duration of the day, and is realized in developmental processes that lead to increased or decreased pigmentation in the adult morph.
definition: r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.
imported from: ro.owl
contributor: Austin Meier
contributor: Chris Mungall
contributor: David Osumi-Sutherland
contributor: Marie Angelique Laporte
has exact synonym: triggered by process

regulates activity of
type: ObjectProperty
sub property of: causally influences
definition: The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
definition editor: Vasundra Touré
imported from: ro.owl

regulates quantity of
type: ObjectProperty
sub property of: causally influences
definition: The entity A has an activity that regulates the quantity or abundance or concentration of the entity B.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly regulates activity of
type: ObjectProperty
sub property of: regulates activity of
definition: The entity A is not immediately upstream of the entity B but A has an activity that regulates an activity performed by B.
definition editor: Vasundra Touré
imported from: ro.owl

decreases by repression quantity of
type: ObjectProperty
sub property of: indirectly negatively regulates quantity of
definition: The entity A has an activity that down-regulates by repression the quantity of B. The down-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly decreases by repression the quantity of protein B (gene product) if and only if A negatively regulates the process of transcription or translation of a nucleic acid element that produces B.
definition editor: Vasundra Touré
imported from: ro.owl

increases by expression quantity of
type: ObjectProperty
sub property of: indirectly positively regulates quantity of
definition: The entity A has an activity that up-regulates by expression the quantity of B. The up-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly increases by expression the quantity of protein B (gene product) if and only if A positively regulates the process of transcription or translation of a nucleic acid element that produces B.
definition editor: Vasundra Touré
imported from: ro.owl

directly positively regulates quantity of
type: ObjectProperty
sub property of: directly regulates quantity of
definition: The entity A has an activity that directly positively regulates the quantity of B.
definition editor: Vasundra Touré
imported from: ro.owl

directly negatively regulates quantity of
type: ObjectProperty
sub property of: directly regulates quantity of
definition: The entity A has an activity that directly negatively regulates the quantity of B.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly positively regulates activity of
type: ObjectProperty
sub property of: indirectly regulates activity of
definition: The entity A is not immediately upstream of the entity B and has an activity that up-regulates an activity performed by B.
definition editor: Vasundra Touré
alternative term: indirectly activates
imported from: ro.owl

destabilizes quantity of
type: ObjectProperty
sub property of: directly negatively regulates quantity of
example of usage: AKT1 destabilizes quantity of FOXO (interaction from Signor database: SIGNOR-252844)
definition: An entity A directly interacts with B and A has an activity that decreases the amount of an entity B by degradating it.
definition editor: Vasundra Touré
imported from: ro.owl

stabilizes quantity of
type: ObjectProperty
sub property of: directly positively regulates quantity of
example of usage: AKT1 stabilizes quantity of XIAP (interaction from Signor database: SIGNOR-119488)
definition: An entity A physically interacts with B and A has an activity that increases the amount of an entity B by stabilizing it.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly negatively regulates activity of
type: ObjectProperty
sub property of: indirectly regulates activity of
definition: The entity A is not immediately upstream of the entity B and has an activity that down-regulates an activity performed by B.
definition editor: Vasundra Touré
alternative term: indirectly inhibits
imported from: ro.owl

directly regulates quantity of
type: ObjectProperty
sub property of: regulates quantity of
definition: The entity A, immediately upstream of B, has an activity that directly regulates the quantity of B.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly regulates quantity of
type: ObjectProperty
sub property of: regulates quantity of
definition: The entity A is not immediately upstream of the entity B, but A has an activity that regulates the quantity or abundance or concentration of B.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly negatively regulates quantity of
type: ObjectProperty
sub property of: indirectly regulates quantity of
definition: The entity A does not physically interact with the entity B, and A has an activity that down-regulates the quantity or abundance or concentration of B.
definition editor: Vasundra Touré
imported from: ro.owl

indirectly positively regulates quantity of
type: ObjectProperty
sub property of: indirectly regulates quantity of
definition: The entity A does not physically interact with the entity B, and A has an activity that up-regulates the quantity or abundance or concentration of B.
definition editor: Vasundra Touré
imported from: ro.owl

is small molecule regulator of
type: ObjectProperty
sub property of: capable of regulating
definition: a relation between a continuant and a process, in which the continuant is a small molecule that regulates the process
imported from: ro.owl
created_by: pg
creation_date: 2020-06-24T13:15:17Z

is small molecule activator of
type: ObjectProperty
sub property of: capable of positively regulating
sub property of: is small molecule regulator of
definition: a relation between a continuant and a process, in which the continuant is a small molecule that activates the process
imported from: ro.owl
created_by: pg
creation_date: 2020-06-24T13:15:26Z

is small molecule inhibitor of
type: ObjectProperty
sub property of: capable of negatively regulating
sub property of: is small molecule regulator of
definition: a relation between a continuant and a process, in which the continuant is a small molecule that inhibits the process
imported from: ro.owl
created_by: pg
creation_date: 2020-06-24T13:15:35Z

constitutively upstream of
type: ObjectProperty
sub property of: causally upstream of, positive effect
definition: p is constitutively upstream of q iff p is causally upstream of q, p is required for execution of q or a part of q, and the execution of p is approximately constant.
imported from: ro.owl
created_by: pg
creation_date: 2022-09-26T06:01:01Z
in subset: valid for go annotation extension
in subset: valid for gocam

removes input for
type: ObjectProperty
sub property of: causally upstream of, negative effect
definition: p removes input for q iff p is causally upstream of q, there exists some c such that p has_input c and q has_input c, p reduces the levels of c, and c is rate limiting for execution of q.
imported from: ro.owl
created_by: pg
creation_date: 2022-09-26T06:06:20Z
in subset: valid for go annotation extension
in subset: valid for gocam

indirectly causally upstream of
type: ObjectProperty
sub property of: causally upstream of
definition: p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
imported from: ro.owl
created_by: pg
creation_date: 2022-09-26T06:07:17Z

indirectly regulates
type: ObjectProperty
sub property of: regulates
sub property of: indirectly causally upstream of
definition: p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
imported from: ro.owl
created_by: pg
creation_date: 2022-09-26T06:08:01Z

disease has infectious agent
type: ObjectProperty
sub property of: disease has basis in
definition: A relationship between a disease and an infectious agent where the material basis of the disease is an infection with some infectious agent.
imported from: ro.owl
created_by: http://orcid.org/0000-0001-5208-3432

has phenotype or disease
type: ObjectProperty
curator note: Do not use this relation directly. It is intended as a grouping for a set of relations regarding presentation of phenotypes and disease.
imported from: ro.owl
Contributor: http://orcid.org/0000-0002-7463-6306
date: 2021-11-05T17:30:14Z

has exposure medium
type: ObjectProperty
sub property of: related via exposure to
definition: X has exposure medium Y if X is an exposure event (process), Y is a material entity, and the stimulus for X is transmitted or carried in Y.
definition source: ExO:0000083
imported from: ro.owl
date: 2021-12-14T20:41:45Z
created_by: https://orcid.org/0000-0002-7463-6306

is agonist of
type: ObjectProperty
sub property of: directly positively regulates activity of
example of usage: mibolerone (CHEBI:34849) is agonist of androgen receptor (PR:P10275)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor activates some activity of the receptor
imported from: ro.owl
creator: https://orcid.org/0000-0003-4423-4370

is inverse agonist of
type: ObjectProperty
sub property of: directly negatively regulates activity of
example of usage: pimavanserin (CHEBI:133017) is inverse agonist of HTR2A (PR:P28223)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor inhibits some activity of the receptor to below basal level
imported from: ro.owl
creator: https://orcid.org/0000-0003-4423-4370

is antagonist of
type: ObjectProperty
sub property of: directly negatively regulates activity of
example of usage: tretinoin (CHEBI:15367) is antagonist of Nuclear receptor ROR-beta (PR:Q92753)
definition: a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor reduces some activity of the receptor to basal level
imported from: ro.owl
creator: https://orcid.org/0000-0003-4423-4370

regulates characteristic
type: ObjectProperty
sub property of: causally related to
definition: A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
imported from: ro.owl
contributor: https://orcid.org/0000-0002-8688-6599

positively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
definition: A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
imported from: ro.owl
contributor: https://orcid.org/0000-0002-8688-6599

negatively regulates characteristic
type: ObjectProperty
sub property of: regulates characteristic
definition: A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
imported from: ro.owl
contributor: https://orcid.org/0000-0002-8688-6599

confers susceptibility to condition
type: ObjectProperty
sub property of: contributes to condition
definition: Relates a gene to condition, such that a variation in this gene predisposes to the development of a condition.
imported from: ro.owl
created_by: http://orcid.org/0000-0002-4142-7153

disease relationship
type: ObjectProperty
definition: This relation groups relations between diseases and any other kind of entity.
curator note: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a disease.
imported from: ro.owl
created_by: cjm
creation_date: 2018-09-26T00:00:32Z

has vaccine component
type: ObjectProperty
domain: VO_0000001
definition: An object property that defines a relation between a vaccine and its component
definition editor: Asiyah Yu Lin
definition editor: Oliver He
imported from: vo.owl

has vaccine antigen
type: ObjectProperty
definition: An object property that specifies a vaccine antigen
editor note: This relation only works for those vaccine antigen that is physically part of a vaccine preparation. It does not include those antigens that are not part of vaccine. For example, a protein antigen expressed in a DNA vaccine is not a part of vaccine pe ser. In this case, the vaccine expresses the protein, but the gene is part of the vaccine, not the protein. For the case, we can use the relation 'DNA vaccine expresses protein antigen' under the relation 'expresses'.
definition editor: Asiyah Yu Lin
definition editor: Oliver He
imported from: vo.owl

has vaccine vector
type: ObjectProperty
sub property of: has vaccine component
range: VO_0000599
definition: A type of 'has vaccine component' relation that is specifically for vaccine vector component
definition editor: Asiyah Yu Lin
definition editor: Oliver He
imported from: vo.owl

vaccinated in route
type: ObjectProperty
domain: VO_0000001
range: VO_0000574
definition: An object property that specifies a relation between a vaccine and a vaccinate route
imported from: vo.owl

immunizes host
type: ObjectProperty
domain: VO_0000001
range: OBI_0100026
definition: A shortcut relation that equals to: 'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine host role' and (role_of some 'organism')))))))). The domain of this relation is a vaccine. The range of this relation is a organism.
definition editor: Asiyah Yu Lin
definition editor: Oliver He
alternative term: immunization for host
alternative term: vaccine immunization for host
imported from: vo.owl

immunizes against pathogen
type: ObjectProperty
domain: VO_0000001
range: Class
  intersection of: OBI_0100026
  intersection of: Restriction
    on property: has role
    some values from: OBI_0000718
definition: A shortcut relation that equals to: processed material and (is_specified_output_of some vaccine preparation) and (has function some (vaccine function and (is realized by only (vaccine immunization and (realizes some ('immunization target role' and (role_of some 'pathogen')))))))) The domain of this relation is a vaccine. The range of this relation is a pathogen (a bacterium, a virus, a fungus, and a parasite) Ranges: organism and 'has role' some 'pathogen role'
definition editor: Oliver He
alternative term: immunization against pathogen
alternative term: immunizes against microbe
alternative term: vaccine immunization against pathogen
term tracker item: https://github.com/vaccineontology/VO/issues/675
imported from: vo.owl

immunizes against disease process
type: ObjectProperty
definition: A shortcut object property that represents a relation between a vaccine and a disease process where the vaccine immunizes a host against a disease process.

up-expressed as immune signature of
type: ObjectProperty
domain: material entity
range: process
definition: An object property that represents a relation between a material entity and biological process
definition editor: Anthony Huffman
definition editor: Oliver He
imported from: vo.owl

has functional parent
type: ObjectProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: has_functional_parent
is cyclic: false
is transitive: false

has parent hydride
type: ObjectProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: has_parent_hydride
is cyclic: false
is transitive: false

is conjugate acid of
type: ObjectProperty
inverse of: is conjugate base of
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: is_conjugate_acid_of
is cyclic: true
is transitive: false

is conjugate base of
type: ObjectProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: is_conjugate_base_of
is cyclic: true
is transitive: false

is enantiomer of
type: ObjectProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: is_enantiomer_of
is cyclic: true
is transitive: false

is substituent group from
type: ObjectProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: is_substituent_group_from
is cyclic: false
is transitive: false

is tautomer of
type: ObjectProperty
type: TransitiveProperty
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: is_tautomer_of
is cyclic: true

has_proper_part
type: ObjectProperty
sub property of: topObjectProperty
type: TransitiveProperty
imported from: dron.owl
imported from: http://purl.org/obo/owl/relationship
has_alternative_id: OBO_REL:0000007
has_obo_namespace: relationship

topObjectProperty
type: ObjectProperty
definition: a administrates b if c owns b and some rights and obligations grounded in the owning relation regarding b are transferred from c to a.
imported from: doid.owl
imported from: ro.owl
comment: A definition of "tranfers" object property can be found in d-acts: http:purl.obolibrary.org/iao/d-acts.owl

has relative risk with no vaccination
type: DatatypeProperty
sub property of: topDataProperty

has relative risk post-vaccination
type: DatatypeProperty
sub property of: topDataProperty

has relative risk post-boost-vaccination
type: DatatypeProperty
sub property of: topDataProperty

has average R0
type: DatatypeProperty
definition: A data property that represents a relation between an infectious agent (such as a viral strain) and a value that is the averge number of transmissions, i.e., the basic reproduction number (or called R0 value).
definition editor: Anthony Huffman, Bill Duncan, Oliver He

has amino acid position
type: DatatypeProperty
sub property of: topDataProperty

has measurement value
type: DatatypeProperty
type: FunctionalProperty
domain: IAO_0000032
range: double
definition: A relation between a scalar measurement data item and a number that quantifies it.
editor note: The range should probably not be restricted to "float". It makes sense to set it to "real". However we do not know how this change will affect SPARQL queries, so we have left the range as-is for now.
imported from: apollo sv.owl
imported from: http://purl.obolibrary.org/obo/obi.owl

has specified value
type: DatatypeProperty
editor preferred label: has specified value
has curation status: IAO_0000120
definition: A relation between a value specification and a number that quantifies it.
editor note: A range of 'real' might be better than 'float'. For now we follow 'has measurement value' until we can consider technical issues with SPARQL queries and reasoning.
definition editor: PERSON: James A. Overton
definition source: OBI
imported from: dron.owl

Pharmaceutical Preparations
type: Class
subclass of: material entity
type: NamedIndividual
Display_Name: Pharmaceutical Preparations
NUI: N0000000001
RxNorm_CUI: 3683
UMLS_CUI: C0013227
code: C176
imported from: NDF-RT.owl

Chemical Ingredients [Chemical/Ingredient]
type: Class
subclass of: material entity
type: NamedIndividual
Display_Name: Chemical Ingredients
NUI: N0000000002
RxNorm_CUI: 991181
code: C178
imported from: NDF-RT.owl

Clinical Kinetics [PK]
type: Class
subclass of: process
type: NamedIndividual
Display_Name: Clinical Kinetics
NUI: N0000000003
RxNorm_CUI: 1030853
UMLS_CUI: C1373163
code: C180
imported from: NDF-RT.owl

Diseases, Manifestations or Physiologic States [Disease/Finding]
type: Class
subclass of: disposition
type: NamedIndividual
Display_Name: Diseases, Manifestations or Physiologic States
NUI: N0000000004
RxNorm_CUI: 989348
UMLS_CUI: C1373233
code: C182
imported from: NDF-RT.owl

Mental Disorders and Manifestations [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Mental Disorders and Manifestations
NUI: N0000000006
RxNorm_CUI: 984721
UMLS_CUI: C2916796
code: C190
imported from: NDF-RT.owl

Infectious Diseases [Disease/Finding]
type: Class
subclass of: IDO_0000436
Display_Name: Infectious Diseases
NUI: N0000000007
RxNorm_CUI: 1023583
SNOMED_CID: 189822004
SNOMED_CID: 190563008
SNOMED_CID: 191415002
SNOMED_CID: 40733004
UMLS_CUI: C0009450
code: C192
imported from: NDF-RT.owl

Elimination [PK]
type: Class
subclass of: Clinical Kinetics [PK]
Display_Name: Elimination
NUI: N0000000022
RxNorm_CUI: 986944
UMLS_CUI: C0221102
code: C222
imported from: NDF-RT.owl

Metabolism [PK]
type: Class
subclass of: Elimination [PK]
Display_Name: Metabolism
NUI: N0000000023
RxNorm_CUI: 1023904
UMLS_CUI: C0025519
code: C224
imported from: NDF-RT.owl

Site of Metabolism [PK]
type: Class
subclass of: Metabolism [PK]
Display_Name: Site of Metabolism
NUI: N0000000024
RxNorm_CUI: 988808
UMLS_CUI: C1373176
code: C226
imported from: NDF-RT.owl

Intestinal Metabolism [PK]
type: Class
subclass of: Site of Metabolism [PK]
type: NamedIndividual
Display_Name: Intestinal Metabolism
NUI: N0000000025
RxNorm_CUI: 988640
UMLS_CUI: C1373177
code: C228
imported from: NDF-RT.owl

Hepatic Metabolism [PK]
type: Class
subclass of: Site of Metabolism [PK]
type: NamedIndividual
Display_Name: Hepatic Metabolism
NUI: N0000000026
RxNorm_CUI: 984512
UMLS_CUI: C1373178
code: C230
imported from: NDF-RT.owl

Route of Excretion [PK]
type: Class
subclass of: Elimination [PK]
Display_Name: Route of Excretion
NUI: N0000000041
RxNorm_CUI: 987962
UMLS_CUI: C1373186
code: C260
imported from: NDF-RT.owl

Renal Excretion [PK]
type: Class
subclass of: Route of Excretion [PK]
type: NamedIndividual
Display_Name: Renal Excretion
NUI: N0000000042
RxNorm_CUI: 986666
UMLS_CUI: C1373187
code: C262
imported from: NDF-RT.owl

Hepatic Excretion [PK]
type: Class
subclass of: Route of Excretion [PK]
Display_Name: Hepatic Excretion
NUI: N0000000043
RxNorm_CUI: 989209
UMLS_CUI: C1373188
code: C264
imported from: NDF-RT.owl

Physiochemical Activity [MoA]
type: Class
subclass of: Cellular or Molecular Interactions [MoA]
type: NamedIndividual
Display_Name: Physiochemical Activity
NUI: N0000000065
RxNorm_CUI: 989958
UMLS_CUI: C1372991
code: C308
imported from: NDF-RT.owl

Small Ion Transport Pump Interactions [MoA]
type: Class
subclass of: Active Transporter Interactions [MoA]
Display_Name: Small Ion Transport Pump Interactions
NUI: N0000000066
RxNorm_CUI: 986087
UMLS_CUI: C1373107
code: C310
imported from: NDF-RT.owl

Active Transporter Interactions [MoA]
type: Class
subclass of: Receptor Interactions [MoA]
Display_Name: Active Transporter Interactions
NUI: N0000000072
RxNorm_CUI: 1031287
UMLS_CUI: C1373104
code: C322
imported from: NDF-RT.owl

Protease Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: Protease Inhibitors
MeSH_DUI: D011480
MeSH_Name: Protease Inhibitors
NUI: N0000000076
RxNorm_CUI: 992709
UMLS_CUI: C2756997
code: C330
imported from: NDF-RT.owl

Immunologic Factors [MoA]
type: Class
subclass of: Immunologic and Biological Factors [MoA]
Display_Name: Immunologic Factors
MeSH_DUI: D007155
MeSH_Name: Immunologic Factors
NUI: N0000000082
RxNorm_CUI: 993127
UMLS_CUI: C2757006
code: C342
imported from: NDF-RT.owl

Receptor Interactions [MoA]
type: Class
subclass of: Cellular or Molecular Interactions [MoA]
Display_Name: Receptor Interactions
NUI: N0000000085
RxNorm_CUI: 988560
UMLS_CUI: C1372999
code: C348
imported from: NDF-RT.owl

Adrenergic Antagonists [MoA]
type: Class
subclass of: Adrenergic Receptor Interactions [MoA]
Display_Name: Adrenergic Antagonists
MeSH_DUI: D018674
MeSH_Name: Adrenergic Antagonists
NUI: N0000000092
RxNorm_CUI: 993129
UMLS_CUI: C2757018
code: C362
imported from: NDF-RT.owl

Cholinergic Muscarinic Receptor Interactions [MoA]
type: Class
subclass of: G-Protein-linked Receptor Interactions [MoA]
subclass of: Cholinergic Interactions [MoA]
Display_Name: Cholinergic Muscarinic Receptor Interactions
NUI: N0000000097
RxNorm_CUI: 986244
UMLS_CUI: C1373009
code: C372
imported from: NDF-RT.owl

Adrenergic alpha-Antagonists [MoA]
type: Class
subclass of: Adrenergic Antagonists [MoA]
type: NamedIndividual
Display_Name: Adrenergic alpha-Antagonists
MeSH_DUI: D000317
MeSH_Name: Adrenergic alpha-Antagonists
NUI: N0000000099
RxNorm_CUI: 1023426
Synonym: Alpha-adrenergic Blocker
UMLS_CUI: C2756989
code: C376
imported from: NDF-RT.owl

Norepinephrine Uptake Inhibitors [MoA]
type: Class
subclass of: Norepinephrine Transporter Interactions [MoA]
type: NamedIndividual
Display_Name: Norepinephrine Uptake Inhibitors
MeSH_DUI: D018759
MeSH_Name: Adrenergic Uptake Inhibitors
NUI: N0000000102
RxNorm_CUI: 989028
UMLS_CUI: C2757023
code: C382
imported from: NDF-RT.owl

Neurotransmitter Transporter Interactions [MoA]
type: Class
subclass of: Active Transporter Interactions [MoA]
Display_Name: Neurotransmitter Transporter Interactions
NUI: N0000000105
RxNorm_CUI: 985066
UMLS_CUI: C1373006
code: C388
imported from: NDF-RT.owl

Serotonin Uptake Inhibitors [MoA]
type: Class
subclass of: Serotonin Transporter Interactions [MoA]
Display_Name: Serotonin Uptake Inhibitors
MeSH_DUI: D017367
MeSH_Name: Serotonin Uptake Inhibitors
NUI: N0000000109
RxNorm_CUI: 992711
UMLS_CUI: C2757053
code: C396
imported from: NDF-RT.owl

Cholinergic Muscarinic Antagonists [MoA]
type: Class
subclass of: Cholinergic Muscarinic Receptor Interactions [MoA]
subclass of: Cholinergic Antagonists [MoA]
Display_Name: Cholinergic Muscarinic Antagonists
NUI: N0000000125
RxNorm_CUI: 984609
UMLS_CUI: C1373102
code: C428
imported from: NDF-RT.owl

Serotonin Antagonists [MoA]
type: Class
subclass of: Serotonin Receptor Interactions [MoA]
type: NamedIndividual
Display_Name: Serotonin Antagonists
MeSH_DUI: D012702
MeSH_Name: Serotonin Antagonists
NUI: N0000000130
RxNorm_CUI: 993156
UMLS_CUI: C2757052
code: C438
imported from: NDF-RT.owl

Enzyme Inhibitors [MoA]
type: Class
subclass of: Enzyme Interactions [MoA]
type: NamedIndividual
Display_Name: Enzyme Inhibitors
MeSH_DUI: D004791
MeSH_Name: Enzyme Inhibitors
NUI: N0000000133
RxNorm_CUI: 1032544
UMLS_CUI: C2756995
code: C444
imported from: NDF-RT.owl

Lipoxygenase Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: Lipoxygenase Inhibitors
MeSH_DUI: D016859
MeSH_Name: Lipoxygenase Inhibitors
NUI: N0000000134
RxNorm_CUI: 1031400
UMLS_CUI: C2757064
code: C446
imported from: NDF-RT.owl

Immunologic Adjuvants [MoA]
type: Class
subclass of: Biological Response Modifiers [MoA]
Display_Name: Immunologic Adjuvants
MeSH_DUI: D000276
MeSH_Name: Adjuvants, Immunologic
NUI: N0000000135
RxNorm_CUI: 989878
Synonym: Adjuvants, Immunologic
UMLS_CUI: C1383096
code: C448
imported from: NDF-RT.owl

Hormone Receptor Agonists [MoA]
type: Class
subclass of: Hormone Receptor Interactions [MoA]
Display_Name: Hormone Receptor Agonists
NUI: N0000000149
RxNorm_CUI: 985200
UMLS_CUI: C1373095
code: C476
imported from: NDF-RT.owl

Protein Synthesis Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: Protein Synthesis Inhibitors
MeSH_DUI: D011500
MeSH_Name: Protein Synthesis Inhibitors
NUI: N0000000150
RxNorm_CUI: 993158
UMLS_CUI: C2757051
code: C478
imported from: NDF-RT.owl

G-Protein-linked Receptor Interactions [MoA]
type: Class
subclass of: Receptor Interactions [MoA]
Display_Name: G-Protein-linked Receptor Interactions
NUI: N0000000152
RxNorm_CUI: 984725
Synonym: G-Protein-linked Receptor-Effector Interactions
UMLS_CUI: C2916797
code: C482
imported from: NDF-RT.owl

Adrenergic Receptor Interactions [MoA]
type: Class
subclass of: G-Protein-linked Receptor Interactions [MoA]
Display_Name: Adrenergic Receptor Interactions
NUI: N0000000153
RxNorm_CUI: 987972
UMLS_CUI: C1373072
code: C484
imported from: NDF-RT.owl

Uncouplers [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: Uncouplers
NUI: N0000000155
RxNorm_CUI: 986674
UMLS_CUI: C1373071
code: C488
imported from: NDF-RT.owl

Chloride Channel Interactions [MoA]
type: Class
subclass of: Ion Channel Interactions [MoA]
Display_Name: Chloride Channel Interactions
NUI: N0000000156
RxNorm_CUI: 987326
UMLS_CUI: C1373070
code: C490
imported from: NDF-RT.owl

Glucocorticoid Receptor Agonists [MoA]
type: Class
subclass of: Corticosteroid Hormone Receptor Agonists [MoA]
Display_Name: Glucocorticoid Receptor Agonists
NUI: N0000000159
RxNorm_CUI: 989879
UMLS_CUI: C1373068
code: C496
imported from: NDF-RT.owl

Enzyme Interactions [MoA]
type: Class
subclass of: Cellular or Molecular Interactions [MoA]
Display_Name: Enzyme Interactions
NUI: N0000000163
RxNorm_CUI: 988200
UMLS_CUI: C1373066
code: C504
imported from: NDF-RT.owl

Serotonin Transporter Interactions [MoA]
type: Class
subclass of: Neurotransmitter Transporter Interactions [MoA]
Display_Name: Serotonin Transporter Interactions
NUI: N0000000167
RxNorm_CUI: 987204
UMLS_CUI: C1373063
code: C512
imported from: NDF-RT.owl

Selective Estrogen Receptor Modulators [MoA]
type: Class
subclass of: Steroid Receptor Modulators [MoA]
Display_Name: Selective Estrogen Receptor Modulators
MeSH_DUI: D020845
MeSH_Name: Selective Estrogen Receptor Modulators
NUI: N0000000168
RxNorm_CUI: 993164
UMLS_CUI: C2757056
code: C514
imported from: NDF-RT.owl

Steroid Receptor Modulators [MoA]
type: Class
subclass of: Hormone Receptor Modulators [MoA]
Display_Name: Steroid Receptor Modulators
NUI: N0000000172
RxNorm_CUI: 987671
UMLS_CUI: C1373061
code: C522
imported from: NDF-RT.owl

Steroid Hormone Receptor Agonists [MoA]
type: Class
subclass of: Hormone Receptor Agonists [MoA]
Display_Name: Steroid Hormone Receptor Agonists
NUI: N0000000182
RxNorm_CUI: 990907
UMLS_CUI: C1373054
code: C542
imported from: NDF-RT.owl

Monoamine Oxidase Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
type: NamedIndividual
Display_Name: Monoamine Oxidase Inhibitors
MeSH_DUI: D008996
MeSH_Name: Monoamine Oxidase Inhibitors
NUI: N0000000184
RxNorm_CUI: 992698
Synonym: MAOI
UMLS_CUI: C2756978
code: C546
imported from: NDF-RT.owl

Progestational Hormone Receptor Agonists [MoA]
type: Class
subclass of: Sex Hormone Receptor Agonists [MoA]
Display_Name: Progestational Hormone Receptor Agonists
NUI: N0000000185
RxNorm_CUI: 986818
UMLS_CUI: C1373052
code: C548
imported from: NDF-RT.owl

Histamine H1 Receptor Antagonists [MoA]
type: Class
subclass of: Histamine Receptor Antagonists [MoA]
Display_Name: Histamine H1 Receptor Antagonists
MeSH_DUI: D006634
MeSH_Name: Histamine H1 Antagonists
NUI: N0000000190
RxNorm_CUI: 992695
Synonym: H1 Receptor Antagonists
Synonym: H1 Receptor Blockers
Synonym: Histamine H1 Antagonists
Synonym: Histamine H1 Blockers
UMLS_CUI: C2757048
code: C558
imported from: NDF-RT.owl

Ion Channel Interactions [MoA]
type: Class
subclass of: Receptor Interactions [MoA]
type: NamedIndividual
Display_Name: Ion Channel Interactions
NUI: N0000000193
RxNorm_CUI: 988382
UMLS_CUI: C1373047
code: C564
imported from: NDF-RT.owl

Serotonin Receptor Interactions [MoA]
type: Class
subclass of: G-Protein-linked Receptor Interactions [MoA]
Display_Name: Serotonin Receptor Interactions
NUI: N0000000198
RxNorm_CUI: 988082
UMLS_CUI: C1373043
code: C574
imported from: NDF-RT.owl

Dopamine Receptor Interactions [MoA]
type: Class
subclass of: G-Protein-linked Receptor Interactions [MoA]
type: NamedIndividual
Display_Name: Dopamine Receptor Interactions
NUI: N0000000203
RxNorm_CUI: 985948
UMLS_CUI: C1373039
code: C584
imported from: NDF-RT.owl

Histamine Receptor Antagonists [MoA]
type: Class
subclass of: Histamine Receptor Interactions [MoA]
Display_Name: Histamine Receptor Antagonists
MeSH_DUI: D006633
MeSH_Name: Histamine Antagonists
NUI: N0000000207
RxNorm_CUI: 989667
Synonym: Histamine Antagonists
UMLS_CUI: C1383092
code: C592
imported from: NDF-RT.owl

Sex Hormone Receptor Agonists [MoA]
type: Class
subclass of: Steroid Hormone Receptor Agonists [MoA]
Display_Name: Sex Hormone Receptor Agonists
NUI: N0000000214
RxNorm_CUI: 990080
UMLS_CUI: C1373033
code: C606
imported from: NDF-RT.owl

Histamine Receptor Interactions [MoA]
type: Class
subclass of: G-Protein-linked Receptor Interactions [MoA]
Display_Name: Histamine Receptor Interactions
NUI: N0000000216
RxNorm_CUI: 989394
UMLS_CUI: C1373031
code: C610
imported from: NDF-RT.owl

Cellular or Molecular Interactions [MoA]
type: Class
subclass of: process
type: NamedIndividual
Display_Name: Cellular or Molecular Interactions
NUI: N0000000223
RxNorm_CUI: 986459
UMLS_CUI: C1373094
code: C624
imported from: NDF-RT.owl

Dopamine Antagonists [MoA]
type: Class
subclass of: Dopamine Receptor Interactions [MoA]
Display_Name: Dopamine Antagonists
MeSH_DUI: D018492
MeSH_Name: Dopamine Antagonists
NUI: N0000000230
RxNorm_CUI: 1032050
UMLS_CUI: C2757008
code: C638
imported from: NDF-RT.owl

Nucleic Acid Synthesis Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
type: NamedIndividual
Display_Name: Nucleic Acid Synthesis Inhibitors
MeSH_DUI: D019384
MeSH_Name: Nucleic Acid Synthesis Inhibitors
NUI: N0000000233
RxNorm_CUI: 993166
UMLS_CUI: C2757009
code: C644
imported from: NDF-RT.owl

Norepinephrine Transporter Interactions [MoA]
type: Class
subclass of: Neurotransmitter Transporter Interactions [MoA]
Display_Name: Norepinephrine Transporter Interactions
NUI: N0000000234
RxNorm_CUI: 988817
UMLS_CUI: C2267223
code: C646
imported from: NDF-RT.owl

Na-K ATPases Interactions [MoA]
type: Class
subclass of: Small Ion Transport Pump Interactions [MoA]
type: NamedIndividual
Display_Name: Na-K ATPases Interactions
NUI: N0000000238
RxNorm_CUI: 987976
UMLS_CUI: C1373085
code: C654
imported from: NDF-RT.owl

Transcription Factor Activity [MoA]
type: Class
subclass of: Receptor Interactions [MoA]
Display_Name: Transcription Factor Activity
NUI: N0000000242
RxNorm_CUI: 1028825
UMLS_CUI: C1148759
code: C662
imported from: NDF-RT.owl

HIV Protease Inhibitors [MoA]
type: Class
subclass of: Protease Inhibitors [MoA]
Display_Name: HIV Protease Inhibitors
MeSH_DUI: D017320
MeSH_Name: HIV Protease Inhibitors
NUI: N0000000246
RxNorm_CUI: 993149
Synonym: Human Immunodeficiency Virus Protease Inhibitors
UMLS_CUI: C2756991
code: C670
imported from: NDF-RT.owl

Biological Response Modifiers [MoA]
type: Class
subclass of: Immunologic Factors [MoA]
Display_Name: Biological Response Modifiers
MeSH_DUI: D015545
MeSH_Name: Biological Response Modifiers
NUI: N0000000247
RxNorm_CUI: 993132
UMLS_CUI: C2757019
code: C672
imported from: NDF-RT.owl

Immunologic and Biological Factors [MoA]
type: Class
subclass of: Cellular or Molecular Interactions [MoA]
Display_Name: Immunologic and Biological Factors
MeSH_DUI: D007151
MeSH_Name: Immunologic and Biological Factors
NUI: N0000000254
RxNorm_CUI: 1032698
UMLS_CUI: C0021048
code: C686
imported from: NDF-RT.owl

Hormone Receptor Modulators [MoA]
type: Class
subclass of: Hormone Receptor Interactions [MoA]
Display_Name: Hormone Receptor Modulators
NUI: N0000000255
RxNorm_CUI: 989214
UMLS_CUI: C1373075
code: C688
imported from: NDF-RT.owl

Hormone Receptor Interactions [MoA]
type: Class
subclass of: Transcription Factor Activity [MoA]
Display_Name: Hormone Receptor Interactions
NUI: N0000000257
RxNorm_CUI: 986361
UMLS_CUI: C1373074
code: C692
imported from: NDF-RT.owl

Congenital Abnormalities [Disease/Finding]
type: Class
subclass of: Congenital, Hereditary, and Neonatal Diseases and Abnormalities [Disease/Finding]
type: NamedIndividual
Display_Name: Congenital Abnormalities
MeSH_CUI: M0000013
MeSH_DUI: D000013
MeSH_Definition: Malformations of organs or body parts during development in utero.
MeSH_Name: Congenital Abnormalities
NUI: N0000000264
RxNorm_CUI: 1021840
SNOMED_CID: 276654001
SNOMED_CID: 276655000
SNOMED_CID: 276720006
Synonym: Abnormalities, Congenital
Synonym: Birth Defects
Synonym: Congenital Defects
Synonym: Defects, Congenital
Synonym: Deformities
UMLS_CUI: C0000768
code: C706
imported from: NDF-RT.owl

Abnormalities, Drug-Induced [Disease/Finding]
type: Class
subclass of: Congenital Abnormalities [Disease/Finding]
Display_Name: Abnormalities, Drug-Induced
MeSH_CUI: M0000014
MeSH_DUI: D000014
MeSH_Definition: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
MeSH_Name: Abnormalities, Drug-Induced
NUI: N0000000265
RxNorm_CUI: 989962
Synonym: Drug-Induced Abnormalities
UMLS_CUI: C0000771
code: C708
imported from: NDF-RT.owl

Abortion, Spontaneous [Disease/Finding]
type: Class
subclass of: Pregnancy Complications [Disease/Finding]
type: NamedIndividual
Display_Name: Abortion, Spontaneous
MeSH_CUI: M0000024
MeSH_DUI: D000022
MeSH_Definition: Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
MeSH_Name: Abortion, Spontaneous
NUI: N0000000268
RxNorm_CUI: 1026142
SNOMED_CID: 17369002
SNOMED_CID: 198631006
Synonym: Miscarriage
Synonym: Spontaneous Abortion
UMLS_CUI: C0000786
code: C714
imported from: NDF-RT.owl

Acne Vulgaris [Disease/Finding]
type: Class
subclass of: Sebaceous Gland Diseases [Disease/Finding]
subclass of: Acneiform Eruptions [Disease/Finding]
type: NamedIndividual
Display_Name: Acne Vulgaris
MeSH_CUI: M0000231
MeSH_DUI: D000152
MeSH_Definition: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
MeSH_Name: Acne Vulgaris
NUI: N0000000288
RxNorm_CUI: 1024380
SNOMED_CID: 88616000
Synonym: Acne
UMLS_CUI: C0001144
code: C754
imported from: NDF-RT.owl

Acquired Immunodeficiency Syndrome [Disease/Finding]
type: Class
subclass of: Slow Virus Diseases [Disease/Finding]
subclass of: HIV Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Acquired Immunodeficiency Syndrome
MeSH_CUI: M0000245
MeSH_DUI: D000163
MeSH_Definition: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
MeSH_Name: Acquired Immunodeficiency Syndrome
NUI: N0000000291
RxNorm_CUI: 1022762
SNOMED_CID: 62479008
Synonym: AIDS
Synonym: Acquired Immune Deficiency Syndrome
Synonym: Acquired Immuno-Deficiency Syndrome
Synonym: Immunodeficiency Syndrome, Acquired
Synonym: Immunologic Deficiency Syndrome, Acquired
UMLS_CUI: C0001175
code: C760
imported from: NDF-RT.owl

Actinomycetales Infections [Disease/Finding]
type: Class
subclass of: Gram-Positive Bacterial Infections [Disease/Finding]
Display_Name: Actinomycetales Infections
MeSH_CUI: M0000289
MeSH_DUI: D000193
MeSH_Definition: Infections with bacteria of the order ACTINOMYCETALES.
MeSH_Name: Actinomycetales Infections
NUI: N0000000299
RxNorm_CUI: 1024017
Synonym: Actinomycete Infections
Synonym: Infections, Actinomycetales
Synonym: Infections, Actinomycete
UMLS_CUI: C0001255
code: C776
imported from: NDF-RT.owl

Adenocarcinoma [Disease/Finding]
type: Class
subclass of: Carcinoma [Disease/Finding]
Display_Name: Adenocarcinoma
MeSH_CUI: M0000355
MeSH_DUI: D000230
MeSH_Definition: A malignant epithelial tumor with a glandular organization.
MeSH_Name: Adenocarcinoma
NUI: N0000000306
RxNorm_CUI: 1023834
SNOMED_CID: 35917007
Synonym: Adenoma, Malignant
UMLS_CUI: C0001418
code: C790
imported from: NDF-RT.owl

Adenoviridae Infections [Disease/Finding]
type: Class
subclass of: DNA Virus Infections [Disease/Finding]
Display_Name: Adenoviridae Infections
MeSH_CUI: M0000404
MeSH_DUI: D000257
MeSH_Definition: Virus diseases caused by the ADENOVIRIDAE.
MeSH_Name: Adenoviridae Infections
NUI: N0000000314
RxNorm_CUI: 1025703
SNOMED_CID: 25225006
Synonym: Adenovirus Infections
Synonym: Infections, Adenoviridae
Synonym: Infections, Adenovirus
UMLS_CUI: C0001486
code: C806
imported from: NDF-RT.owl

Adenovirus Infections, Human [Disease/Finding]
type: Class
subclass of: Adenoviridae Infections [Disease/Finding]
Display_Name: Adenovirus Infections, Human
MeSH_CUI: M0000405
MeSH_DUI: D000258
MeSH_Definition: Respiratory and conjunctival infections caused by 33 identified serotypes of human adenoviruses.
MeSH_Name: Adenovirus Infections, Human
NUI: N0000000315
RxNorm_CUI: 1022278
Synonym: Human Adenovirus Infections
Synonym: Infections, Human Adenovirus
UMLS_CUI: C0001487
code: C808
imported from: NDF-RT.owl

Amebiasis [Disease/Finding]
type: Class
subclass of: Protozoan Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Amebiasis
MeSH_CUI: M0000878
MeSH_DUI: D000562
MeSH_Definition: Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.
MeSH_Name: Amebiasis
NUI: N0000000365
RxNorm_CUI: 1023982
SNOMED_CID: 105637008
SNOMED_CID: 111910009
SNOMED_CID: 388759003
Synonym: Amoebiasis
UMLS_CUI: C0002438
code: C908
imported from: NDF-RT.owl

Amenorrhea [Disease/Finding]
type: Class
subclass of: Menstruation Disturbances [Disease/Finding]
type: NamedIndividual
Display_Name: Amenorrhea
MeSH_CUI: M0000887
MeSH_DUI: D000568
MeSH_Definition: Absence of menstruation.
MeSH_Name: Amenorrhea
NUI: N0000000368
RxNorm_CUI: 1024010
SNOMED_CID: 14302001
UMLS_CUI: C0002453
code: C914
imported from: NDF-RT.owl

Amino Acid Metabolism, Inborn Errors [Disease/Finding]
type: Class
subclass of: Metabolism, Inborn Errors [Disease/Finding]
Display_Name: Amino Acid Metabolism, Inborn Errors
MeSH_CUI: M0000918
MeSH_DUI: D000592
MeSH_Definition: Disorders affecting amino acid metabolism. The majority of these disorders are inherited and present in the neonatal period with metabolic disturbances (e.g., ACIDOSIS) and neurologic manifestations. They are present at birth, although they may not become symptomatic until later in life.
MeSH_Name: Amino Acid Metabolism, Inborn Errors
NUI: N0000000369
RxNorm_CUI: 1022859
SNOMED_CID: 190680002
SNOMED_CID: 42930003
SNOMED_CID: 44779003
Synonym: Amino Acid Metabolism Disorders, Inborn
Synonym: Amino Acid Metabolism, Inborn Error
Synonym: Amino Acidopathies, Congenital
Synonym: Amino Acidopathies, Inborn
Synonym: Congenital Amino Acidopathies
Synonym: Inborn Errors, Amino Acid Metabolism
UMLS_CUI: C0002514
code: C916
imported from: NDF-RT.owl

Amyloidosis [Disease/Finding]
type: Class
subclass of: Proteostasis Deficiencies [Disease/Finding]
type: NamedIndividual
Display_Name: Amyloidosis
MeSH_CUI: M0001053
MeSH_DUI: D000686
MeSH_Definition: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
MeSH_Name: Amyloidosis
NUI: N0000000375
RxNorm_CUI: 1024175
SNOMED_CID: 17602002
UMLS_CUI: C0002726
code: C928
imported from: NDF-RT.owl

Anemia [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Anemia
MeSH_CUI: M0001119
MeSH_DUI: D000740
MeSH_Definition: A reduction in the number of circulating erythrocytes or in the quantity of hemoglobin.
MeSH_Name: Anemia
NUI: N0000000384
RxNorm_CUI: 1024481
SNOMED_CID: 267531008
SNOMED_CID: 271737000
UMLS_CUI: C0002871
code: C946
imported from: NDF-RT.owl

Anxiety Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Anxiety Disorders
MeSH_CUI: M0001533
MeSH_DUI: D001008
MeSH_Definition: Persistent and disabling ANXIETY.
MeSH_Name: Anxiety Disorders
NUI: N0000000435
RxNorm_CUI: 1023219
SNOMED_CID: 197480006
UMLS_CUI: C0003469
code: C1048
imported from: NDF-RT.owl

Aortic Stenosis, Subvalvular [Disease/Finding]
type: Class
subclass of: Aortic Valve Stenosis [Disease/Finding]
Display_Name: Aortic Stenosis, Subvalvular
MeSH_CUI: M0001552
MeSH_DUI: D001020
MeSH_Definition: A pathological constriction occurring in the region below the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
MeSH_Name: Aortic Stenosis, Subvalvular
NUI: N0000000442
RxNorm_CUI: 1025918
Synonym: Aortic Subvalvular Stenosis
Synonym: Subvalvular Aortic Stenosis
UMLS_CUI: C0003500
code: C1062
imported from: NDF-RT.owl

Aortic Valve Stenosis [Disease/Finding]
type: Class
subclass of: Heart Valve Diseases [Disease/Finding]
subclass of: Ventricular Outflow Obstruction [Disease/Finding]
Display_Name: Aortic Valve Stenosis
MeSH_CUI: M0001557
MeSH_DUI: D001024
MeSH_Definition: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
MeSH_Name: Aortic Valve Stenosis
NUI: N0000000445
RxNorm_CUI: 1021926
SNOMED_CID: 60573004
Synonym: Aortic Stenosis
UMLS_CUI: C0003507
code: C1068
imported from: NDF-RT.owl

Arbovirus Infections [Disease/Finding]
type: Class
subclass of: DOID 934
Display_Name: Arbovirus Infections
MeSH_CUI: M0001658
MeSH_DUI: D001102
MeSH_Definition: Infections caused by arthropod-borne viruses, general or unspecified.
MeSH_Name: Arbovirus Infections
NUI: N0000000462
RxNorm_CUI: 1023709
SNOMED_CID: 40610006
UMLS_CUI: C0003723
code: C1102
imported from: NDF-RT.owl

Arrhythmias, Cardiac [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Arrhythmias, Cardiac
MeSH_CUI: M0001715
MeSH_DUI: D001145
MeSH_Definition: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
MeSH_Name: Arrhythmias, Cardiac
NUI: N0000000469
RxNorm_CUI: 1023395
SNOMED_CID: 195107004
Synonym: Arrhythmia
Synonym: Arrythmia
Synonym: Cardiac Arrhythmia
Synonym: Cardiac Arrhythmias
Synonym: Cardiac Dysrhythmia
UMLS_CUI: C0003811
code: C1116
imported from: NDF-RT.owl

Arthritis [Disease/Finding]
type: Class
subclass of: Joint Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Arthritis
MeSH_CUI: M0001741
MeSH_DUI: D001168
MeSH_Name: Arthritis
NUI: N0000000478
RxNorm_CUI: 1023652
SNOMED_CID: 3723001
UMLS_CUI: C0003864
code: C1134
imported from: NDF-RT.owl

Arthritis, Rheumatoid [Disease/Finding]
type: Class
subclass of: Arthritis [Disease/Finding]
subclass of: Autoimmune Diseases [Disease/Finding]
subclass of: Rheumatic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Arthritis, Rheumatoid
MeSH_CUI: M0001750
MeSH_DUI: D001172
MeSH_Definition: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
MeSH_Name: Arthritis, Rheumatoid
NUI: N0000000482
RxNorm_CUI: 1023050
SNOMED_CID: 69896004
Synonym: Rheumatoid Arthritis
UMLS_CUI: C0003873
code: C1142
imported from: NDF-RT.owl

Ascariasis [Disease/Finding]
type: Class
subclass of: Ascaridida Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Ascariasis
MeSH_CUI: M0001785
MeSH_DUI: D001196
MeSH_Definition: Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.
MeSH_Name: Ascariasis
NUI: N0000000488
RxNorm_CUI: 1022405
SNOMED_CID: 2435008
UMLS_CUI: C0003950
code: C1154
imported from: NDF-RT.owl

Atrial Fibrillation [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
type: NamedIndividual
Display_Name: Atrial Fibrillation
MeSH_CUI: M0001926
MeSH_DUI: D001281
MeSH_Definition: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
MeSH_Name: Atrial Fibrillation
NUI: N0000000507
RxNorm_CUI: 1023706
SNOMED_CID: 49436004
Synonym: Auricular Fibrillation
UMLS_CUI: C0004238
code: C1192
imported from: NDF-RT.owl

Atrial Flutter [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
type: NamedIndividual
Display_Name: Atrial Flutter
MeSH_CUI: M0001927
MeSH_DUI: D001282
MeSH_Definition: Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).
MeSH_Name: Atrial Flutter
NUI: N0000000508
RxNorm_CUI: 985206
SNOMED_CID: 5370000
Synonym: Auricular Flutter
UMLS_CUI: C0004239
code: C1194
imported from: NDF-RT.owl

Autoimmune Diseases [Disease/Finding]
type: Class
subclass of: Immune System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Autoimmune Diseases
MeSH_CUI: M0001989
MeSH_DUI: D001327
MeSH_Definition: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
MeSH_Name: Autoimmune Diseases
NUI: N0000000514
RxNorm_CUI: 1026092
SNOMED_CID: 85828009
UMLS_CUI: C0004364
code: C1206
imported from: NDF-RT.owl

Bacterial Infections and Mycoses [Disease/Finding]
type: Class
subclass of: IDO_0000436
Display_Name: Bacterial Infections and Mycoses
MeSH_CUI: M0002125
MeSH_DUI: D001423
MeSH_Definition: Infections caused by bacteria and fungi, general, specified, or unspecified.
MeSH_Name: Bacterial Infections and Mycoses
NUI: N0000000523
RxNorm_CUI: 986958
UMLS_CUI: C0004615
code: C1224
imported from: NDF-RT.owl

Bacterial Infections [Disease/Finding]
type: Class
subclass of: Bacterial Infections and Mycoses [Disease/Finding]
type: NamedIndividual
Display_Name: Bacterial Infections
MeSH_CUI: M0002126
MeSH_DUI: D001424
MeSH_Definition: Infections by bacteria, general or unspecified.
MeSH_Name: Bacterial Infections
NUI: N0000000524
RxNorm_CUI: 1022614
SNOMED_CID: 186335000
SNOMED_CID: 301811001
SNOMED_CID: 87628006
Synonym: Bacterial Infection
Synonym: Infection, Bacterial
Synonym: Infections, Bacterial
UMLS_CUI: C0004623
code: C1226
imported from: NDF-RT.owl

Basal Ganglia Diseases [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
Display_Name: Basal Ganglia Diseases
MeSH_CUI: M0002198
MeSH_DUI: D001480
MeSH_Definition: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
MeSH_Name: Basal Ganglia Diseases
NUI: N0000000536
RxNorm_CUI: 1030459
SNOMED_CID: 70835005
Synonym: Basal Ganglia Disorders
UMLS_CUI: C0004782
code: C1250
imported from: NDF-RT.owl

Mental Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders and Manifestations [Disease/Finding]
type: NamedIndividual
Display_Name: Mental Disorders
MeSH_CUI: M0002289
MeSH_DUI: D001523
MeSH_Definition: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
MeSH_Name: Mental Disorders
NUI: N0000000538
RxNorm_CUI: 1022308
SNOMED_CID: 74732009
UMLS_CUI: C0004936
code: C1254
imported from: NDF-RT.owl

Urinary Bladder Diseases [Disease/Finding]
type: Class
subclass of: Urologic Diseases [Disease/Finding]
Display_Name: Urinary Bladder Diseases
MeSH_CUI: M0002630
MeSH_DUI: D001745
MeSH_Definition: Pathological processes of the URINARY BLADDER.
MeSH_Name: Urinary Bladder Diseases
NUI: N0000000560
RxNorm_CUI: 1022750
SNOMED_CID: 42643001
Synonym: Bladder Diseases
UMLS_CUI: C0005686
code: C1298
imported from: NDF-RT.owl

Urinary Bladder Neck Obstruction [Disease/Finding]
type: Class
subclass of: Urinary Bladder Diseases [Disease/Finding]
subclass of: Urethral Obstruction [Disease/Finding]
type: NamedIndividual
Display_Name: Urinary Bladder Neck Obstruction
MeSH_CUI: M0002634
MeSH_DUI: D001748
MeSH_Definition: Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.
MeSH_Name: Urinary Bladder Neck Obstruction
NUI: N0000000563
RxNorm_CUI: 1023806
SNOMED_CID: 399072004
Synonym: Bladder Neck Obstruction
Synonym: Bladder Outlet Obstruction
UMLS_CUI: C0005694
code: C1304
imported from: NDF-RT.owl

Blast Crisis [Disease/Finding]
type: Class
subclass of: Cell Transformation, Neoplastic [Disease/Finding]
subclass of: Leukemia, Myelogenous, Chronic, BCR-ABL Positive [Disease/Finding]
type: NamedIndividual
Display_Name: Blast Crisis
MeSH_CUI: M0002638
MeSH_DUI: D001752
MeSH_Definition: An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
MeSH_Name: Blast Crisis
NUI: N0000000566
RxNorm_CUI: 1024400
SNOMED_CID: 413656006
Synonym: Blast Phase
UMLS_CUI: C0005699
code: C1310
imported from: NDF-RT.owl

Blood Coagulation Disorders [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Blood Coagulation Disorders
MeSH_CUI: M0002683
MeSH_DUI: D001778
MeSH_Definition: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.
MeSH_Name: Blood Coagulation Disorders
NUI: N0000000575
RxNorm_CUI: 1022276
SNOMED_CID: 362970003
SNOMED_CID: 64779008
Synonym: Coagulation Disorders, Blood
Synonym: Disorders, Blood Coagulation
UMLS_CUI: C0005779
code: C1328
imported from: NDF-RT.owl

Blood Platelet Disorders [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Blood Platelet Disorders
MeSH_CUI: M0002703
MeSH_DUI: D001791
MeSH_Definition: Disorders caused by abnormalities in platelet count or function.
MeSH_Name: Blood Platelet Disorders
NUI: N0000000577
RxNorm_CUI: 1025348
SNOMED_CID: 22716005
Synonym: Thrombocytopathy
UMLS_CUI: C0005818
code: C1332
imported from: NDF-RT.owl

Blood Protein Disorders [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
Display_Name: Blood Protein Disorders
MeSH_CUI: M0002708
MeSH_DUI: D001796
MeSH_Name: Blood Protein Disorders
NUI: N0000000578
RxNorm_CUI: 1027678
UMLS_CUI: C0005830
code: C1334
imported from: NDF-RT.owl

Bone Marrow Diseases [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
Display_Name: Bone Marrow Diseases
MeSH_CUI: M0002788
MeSH_DUI: D001855
MeSH_Name: Bone Marrow Diseases
NUI: N0000000589
RxNorm_CUI: 1023913
SNOMED_CID: 127035006
UMLS_CUI: C0005956
code: C1356
imported from: NDF-RT.owl

Brain Damage, Chronic [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Brain Damage, Chronic
MeSH_CUI: M0002872
MeSH_DUI: D001925
MeSH_Definition: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
MeSH_Name: Brain Damage, Chronic
NUI: N0000000603
RxNorm_CUI: 1024348
SNOMED_CID: 78689005
Synonym: Chronic Encephalopathy
Synonym: Encephalopathy, Chronic
UMLS_CUI: C0006109
code: C1384
imported from: NDF-RT.owl

Brain Diseases [Disease/Finding]
type: Class
subclass of: Central Nervous System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Brain Diseases
MeSH_CUI: M0002874
MeSH_DUI: D001927
MeSH_Definition: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
MeSH_Name: Brain Diseases
NUI: N0000000605
RxNorm_CUI: 986258
SNOMED_CID: 81308009
Synonym: Brain Disorders
Synonym: CNS Disorders, Intracranial
Synonym: Central Nervous System Disorders, Intracranial
Synonym: Central Nervous System Intracranial Disorders
Synonym: Encephalon Diseases
Synonym: Intracranial CNS Disorders
Synonym: Intracranial Central Nervous System Disorders
UMLS_CUI: C0006111
code: C1388
imported from: NDF-RT.owl

Brain Diseases, Metabolic [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
subclass of: Metabolic Diseases [Disease/Finding]
Display_Name: Brain Diseases, Metabolic
MeSH_CUI: M0002875
MeSH_DUI: D001928
MeSH_Definition: Acquired or inborn metabolic diseases that produce brain dysfunction or damage. These include primary (i.e., disorders intrinsic to the brain) and secondary (i.e., extracranial) metabolic conditions that adversely affect cerebral function.
MeSH_Name: Brain Diseases, Metabolic
NUI: N0000000606
RxNorm_CUI: 1024852
SNOMED_CID: 50122000
Synonym: Brain Disorders, Metabolic
Synonym: Brain Syndrome, Metabolic
Synonym: Encephalopathies, Metabolic
Synonym: Metabolic Brain Diseases
Synonym: Metabolic Brain Syndrome
Synonym: Metabolic Brain Syndromes
Synonym: Metabolic Disorders, Brain
Synonym: Metabolic Encephalopathies
UMLS_CUI: C0006112
code: C1390
imported from: NDF-RT.owl

Brain Neoplasms [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
subclass of: Central Nervous System Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: Brain Neoplasms
MeSH_CUI: M0002885
MeSH_DUI: D001932
MeSH_Definition: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
MeSH_Name: Brain Neoplasms
NUI: N0000000609
RxNorm_CUI: 1025641
SNOMED_CID: 126952004
SNOMED_CID: 189537005
Synonym: Brain Tumors
Synonym: Neoplasms, Brain
UMLS_CUI: C0006118
code: C1396
imported from: NDF-RT.owl

Breast Diseases [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Breast Diseases
MeSH_CUI: M0002906
MeSH_DUI: D001941
MeSH_Definition: Pathological processes of the BREAST.
MeSH_Name: Breast Diseases
NUI: N0000000611
RxNorm_CUI: 1025046
SNOMED_CID: 79604008
UMLS_CUI: C0006145
code: C1400
imported from: NDF-RT.owl

Breast Neoplasms [Disease/Finding]
type: Class
subclass of: Breast Diseases [Disease/Finding]
subclass of: Neoplasms by Site [Disease/Finding]
type: NamedIndividual
Display_Name: Breast Neoplasms
MeSH_CUI: M0002910
MeSH_DUI: D001943
MeSH_Definition: Tumors or cancer of the human BREAST.
MeSH_Name: Breast Neoplasms
NUI: N0000000612
RxNorm_CUI: 1023282
SNOMED_CID: 126926005
Synonym: Breast Tumors
Synonym: Neoplasms, Breast
Synonym: Tumors, Breast
UMLS_CUI: C1458155
code: C1402
imported from: NDF-RT.owl

Candidiasis [Disease/Finding]
type: Class
subclass of: Mycoses [Disease/Finding]
Display_Name: Candidiasis
MeSH_CUI: M0003258
MeSH_DUI: D002177
MeSH_Definition: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
MeSH_Name: Candidiasis
NUI: N0000000650
RxNorm_CUI: 1022538
SNOMED_CID: 78048006
Synonym: Moniliasis
UMLS_CUI: C0006840
code: C1478
imported from: NDF-RT.owl

Candidiasis, Vulvovaginal [Disease/Finding]
type: Class
subclass of: Candidiasis [Disease/Finding]
subclass of: Vulvovaginitis [Disease/Finding]
type: NamedIndividual
Display_Name: Candidiasis, Vulvovaginal
MeSH_CUI: M0003262
MeSH_DUI: D002181
MeSH_Definition: Infection of the VULVA and VAGINA with a fungus of the genus CANDIDA.
MeSH_Name: Candidiasis, Vulvovaginal
NUI: N0000000654
RxNorm_CUI: 1024776
SNOMED_CID: 72605008
Synonym: Moniliasis, Vulvovaginal
UMLS_CUI: C0700345
code: C1486
imported from: NDF-RT.owl

Carcinoma [Disease/Finding]
type: Class
subclass of: Neoplasms, Glandular and Epithelial [Disease/Finding]
Display_Name: Carcinoma
MeSH_CUI: M0003424
MeSH_DUI: D002277
MeSH_Definition: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
MeSH_Name: Carcinoma
NUI: N0000000664
RxNorm_CUI: 1024578
SNOMED_CID: 68453008
Synonym: Epithelial Neoplasms, Malignant
Synonym: Epithelial Tumors, Malignant
Synonym: Epithelioma
Synonym: Malignant Epithelial Neoplasms
Synonym: Neoplasms, Malignant Epithelial
UMLS_CUI: C0007097
code: C1506
imported from: NDF-RT.owl

Carcinoma, Renal Cell [Disease/Finding]
type: Class
subclass of: Adenocarcinoma [Disease/Finding]
subclass of: Kidney Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: Carcinoma, Renal Cell
MeSH_CUI: M0003442
MeSH_DUI: D002292
MeSH_Definition: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
MeSH_Name: Carcinoma, Renal Cell
NUI: N0000000678
RxNorm_CUI: 1025619
SNOMED_CID: 188251003
Synonym: Adenocarcinoma, Renal Cell
Synonym: Nephroid Carcinoma
Synonym: Renal Cell Cancer
Synonym: Renal Cell Carcinoma
UMLS_CUI: C0007134
code: C1534
imported from: NDF-RT.owl

Cardiac Output, Low [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
subclass of: Signs and Symptoms [Disease/Finding]
type: NamedIndividual
Display_Name: Cardiac Output, Low
MeSH_CUI: M0003453
MeSH_DUI: D002303
MeSH_Definition: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
MeSH_Name: Cardiac Output, Low
NUI: N0000000683
RxNorm_CUI: 1024618
SNOMED_CID: 86318000
Synonym: Low Cardiac Output
UMLS_CUI: C0007166
code: C1544
imported from: NDF-RT.owl

Cardiomyopathy, Hypertrophic [Disease/Finding]
type: Class
subclass of: Aortic Stenosis, Subvalvular [Disease/Finding]
subclass of: Cardiomyopathies [Disease/Finding]
type: NamedIndividual
Display_Name: Cardiomyopathy, Hypertrophic
MeSH_CUI: M0003464
MeSH_DUI: D002312
MeSH_Definition: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
MeSH_Name: Cardiomyopathy, Hypertrophic
NUI: N0000000687
RxNorm_CUI: 1024263
SNOMED_CID: 233873004
SNOMED_CID: 45227007
Synonym: Cardiomyopathy, Hypertrophic Obstructive
UMLS_CUI: C0007194
code: C1552
imported from: NDF-RT.owl

Cardiovascular Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Cardiovascular Diseases
MeSH_CUI: M0003473
MeSH_DUI: D002318
MeSH_Definition: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
MeSH_Name: Cardiovascular Diseases
NUI: N0000000689
RxNorm_CUI: 1022075
SNOMED_CID: 105980002
SNOMED_CID: 49601007
UMLS_CUI: C0007222
code: C1556
imported from: NDF-RT.owl

Cell Transformation, Neoplastic [Disease/Finding]
type: Class
subclass of: Neoplastic Processes [Disease/Finding]
Display_Name: Cell Transformation, Neoplastic
MeSH_CUI: M0003771
MeSH_DUI: D002471
MeSH_Definition: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
MeSH_Name: Cell Transformation, Neoplastic
NUI: N0000000705
RxNorm_CUI: 990924
Synonym: Neoplastic Cell Transformation
Synonym: Neoplastic Transformation, Cell
Synonym: Transformation, Neoplastic Cell
UMLS_CUI: C0007621
code: C1588
imported from: NDF-RT.owl

Central Nervous System Diseases [Disease/Finding]
type: Class
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Central Nervous System Diseases
MeSH_CUI: M0003805
MeSH_DUI: D002493
MeSH_Definition: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
MeSH_Name: Central Nervous System Diseases
NUI: N0000000709
RxNorm_CUI: 1023588
SNOMED_CID: 23853001
Synonym: CNS Diseases
Synonym: Central Nervous System Disorders
UMLS_CUI: C0007682
code: C1596
imported from: NDF-RT.owl

Central Nervous System Infections [Disease/Finding]
type: Class
subclass of: Bacterial Infections and Mycoses [Disease/Finding]
subclass of: Central Nervous System Diseases [Disease/Finding]
Display_Name: Central Nervous System Infections
MeSH_CUI: M0003806
MeSH_DUI: D002494
MeSH_Definition: Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.
MeSH_Name: Central Nervous System Infections
NUI: N0000000710
RxNorm_CUI: 1026115
SNOMED_CID: 128117002
Synonym: Central Nervous System Infection
Synonym: Infections, Central Nervous System
UMLS_CUI: C0007684
code: C1598
imported from: NDF-RT.owl

Cerebral Hemorrhage [Disease/Finding]
type: Class
subclass of: Intracranial Hemorrhages [Disease/Finding]
type: NamedIndividual
Display_Name: Cerebral Hemorrhage
MeSH_CUI: M0003884
MeSH_DUI: D002543
MeSH_Definition: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
MeSH_Name: Cerebral Hemorrhage
NUI: N0000000721
RxNorm_CUI: 1103691
SNOMED_CID: 1508000
SNOMED_CID: 274100004
SNOMED_CID: 73020009
Synonym: Brain Hemorrhage, Cerebral
Synonym: Cerebral Parenchymal Hemorrhage
Synonym: Hemorrhage, Cerebral
Synonym: Hemorrhage, Cerebrum
Synonym: Intracerebral Hemorrhage
UMLS_CUI: C2937358
code: C1620
imported from: NDF-RT.owl

Cerebrovascular Disorders [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
subclass of: Vascular Diseases [Disease/Finding]
Display_Name: Cerebrovascular Disorders
MeSH_CUI: M0003914
MeSH_DUI: D002561
MeSH_Definition: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES; or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
MeSH_Name: Cerebrovascular Disorders
NUI: N0000000730
RxNorm_CUI: 1022010
SNOMED_CID: 62914000
Synonym: Brain Vascular Disorders
Synonym: Intracranial Vascular Disorders
Synonym: Vascular Diseases, Intracranial
UMLS_CUI: C0007820
code: C1638
imported from: NDF-RT.owl

Chlamydia Infections [Disease/Finding]
type: Class
subclass of: Chlamydiaceae Infections [Disease/Finding]
subclass of: Sexually Transmitted Diseases, Bacterial [Disease/Finding]
type: NamedIndividual
Display_Name: Chlamydia Infections
MeSH_CUI: M0004107
MeSH_DUI: D002690
MeSH_Definition: Infections with bacteria of the genus CHLAMYDIA.
MeSH_Name: Chlamydia Infections
NUI: N0000000754
RxNorm_CUI: 1023626
SNOMED_CID: 105629000
Synonym: Infections, Chlamydia
UMLS_CUI: C0008149
code: C1686
imported from: NDF-RT.owl

Chlamydiaceae Infections [Disease/Finding]
type: Class
subclass of: Gram-Negative Bacterial Infections [Disease/Finding]
Display_Name: Chlamydiaceae Infections
MeSH_CUI: M0004111
MeSH_DUI: D002694
MeSH_Definition: Infections with bacteria of the family CHLAMYDIACEAE.
MeSH_Name: Chlamydiaceae Infections
NUI: N0000000755
RxNorm_CUI: 987383
UMLS_CUI: C0008153
code: C1688
imported from: NDF-RT.owl

Clostridium Infections [Disease/Finding]
type: Class
subclass of: Gram-Positive Bacterial Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Clostridium Infections
MeSH_CUI: M0004637
MeSH_DUI: D003015
MeSH_Definition: Infections with bacteria of the genus CLOSTRIDIUM.
MeSH_Name: Clostridium Infections
NUI: N0000000796
RxNorm_CUI: 989684
SNOMED_CID: 56688005
Synonym: Infections, Clostridium
UMLS_CUI: C0009062
code: C1770
imported from: NDF-RT.owl

Coccidiosis [Disease/Finding]
type: Class
subclass of: Protozoan Infections [Disease/Finding]
Display_Name: Coccidiosis
MeSH_CUI: M0004678
MeSH_DUI: D003048
MeSH_Definition: Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA.
MeSH_Name: Coccidiosis
NUI: N0000000801
RxNorm_CUI: 1023852
SNOMED_CID: 62005008
UMLS_CUI: C0009187
code: C1780
imported from: NDF-RT.owl

Colitis [Disease/Finding]
type: Class
subclass of: Colonic Diseases [Disease/Finding]
subclass of: Gastroenteritis [Disease/Finding]
type: NamedIndividual
Display_Name: Colitis
MeSH_CUI: M0004770
MeSH_DUI: D003092
MeSH_Definition: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
MeSH_Name: Colitis
NUI: N0000000806
RxNorm_CUI: 1024342
SNOMED_CID: 64226004
UMLS_CUI: C0009319
code: C1790
imported from: NDF-RT.owl

Colitis, Ulcerative [Disease/Finding]
type: Class
subclass of: Colitis [Disease/Finding]
subclass of: Inflammatory Bowel Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Colitis, Ulcerative
MeSH_CUI: M0004771
MeSH_DUI: D003093
MeSH_Definition: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
MeSH_Name: Colitis, Ulcerative
NUI: N0000000807
RxNorm_CUI: 1025158
SNOMED_CID: 64766004
Synonym: Ulcerative Colitis
UMLS_CUI: C0009324
code: C1792
imported from: NDF-RT.owl

Colonic Diseases [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Colonic Diseases
MeSH_CUI: M0004814
MeSH_DUI: D003108
MeSH_Definition: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
MeSH_Name: Colonic Diseases
NUI: N0000000811
RxNorm_CUI: 1025915
SNOMED_CID: 128524007
UMLS_CUI: C0009373
code: C1800
imported from: NDF-RT.owl

Colonic Diseases, Functional [Disease/Finding]
type: Class
subclass of: Colonic Diseases [Disease/Finding]
Display_Name: Colonic Diseases, Functional
MeSH_CUI: M0004815
MeSH_DUI: D003109
MeSH_Definition: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
MeSH_Name: Colonic Diseases, Functional
NUI: N0000000812
RxNorm_CUI: 1026889
Synonym: Functional Colonic Diseases
UMLS_CUI: C0009374
code: C1802
imported from: NDF-RT.owl

Coma [Disease/Finding]
type: Class
subclass of: Unconsciousness [Disease/Finding]
type: NamedIndividual
Display_Name: Coma
MeSH_CUI: M0004841
MeSH_DUI: D003128
MeSH_Definition: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
MeSH_Name: Coma
NUI: N0000000819
RxNorm_CUI: 988251
SNOMED_CID: 371632003
Synonym: Comatose
UMLS_CUI: C0009421
code: C1816
imported from: NDF-RT.owl

Conjunctival Diseases [Disease/Finding]
type: Class
subclass of: Eye Diseases [Disease/Finding]
Display_Name: Conjunctival Diseases
MeSH_CUI: M0005013
MeSH_DUI: D003229
MeSH_Name: Conjunctival Diseases
NUI: N0000000831
RxNorm_CUI: 1024252
SNOMED_CID: 59698003
UMLS_CUI: C0009759
code: C1840
imported from: NDF-RT.owl

Conjunctivitis [Disease/Finding]
type: Class
subclass of: Conjunctival Diseases [Disease/Finding]
Display_Name: Conjunctivitis
MeSH_CUI: M0005015
MeSH_DUI: D003231
MeSH_Name: Conjunctivitis
NUI: N0000000833
RxNorm_CUI: 1026151
SNOMED_CID: 193875009
SNOMED_CID: 9826008
UMLS_CUI: C0009763
code: C1844
imported from: NDF-RT.owl

Conjunctivitis, Allergic [Disease/Finding]
type: Class
subclass of: Conjunctivitis [Disease/Finding]
subclass of: Hypersensitivity, Immediate [Disease/Finding]
type: NamedIndividual
Display_Name: Conjunctivitis, Allergic
MeSH_CUI: M0005017
MeSH_DUI: D003233
MeSH_Definition: Conjunctivitis due to hypersensitivity to various allergens.
MeSH_Name: Conjunctivitis, Allergic
NUI: N0000000835
RxNorm_CUI: 984750
SNOMED_CID: 231854006
Synonym: Allergic Conjunctivitis
Synonym: Conjunctivitis, Atopic
UMLS_CUI: C0009766
code: C1848
imported from: NDF-RT.owl

Connective Tissue Diseases [Disease/Finding]
type: Class
subclass of: Skin and Connective Tissue Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Connective Tissue Diseases
MeSH_CUI: M0005027
MeSH_DUI: D003240
MeSH_Definition: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.
MeSH_Name: Connective Tissue Diseases
NUI: N0000000839
RxNorm_CUI: 986518
SNOMED_CID: 105969002
UMLS_CUI: C0009782
code: C1856
imported from: NDF-RT.owl

Consciousness Disorders [Disease/Finding]
type: Class
subclass of: Neurobehavioral Manifestations [Disease/Finding]
subclass of: Delirium, Dementia, Amnestic, Cognitive Disorders [Disease/Finding]
Display_Name: Consciousness Disorders
MeSH_CUI: M0005031
MeSH_DUI: D003244
MeSH_Definition: Organic mental disorders in which there is impairment of the ability to maintain awareness of self and environment and to respond to environmental stimuli. Dysfunction of the cerebral hemispheres or brain stem RETICULAR FORMATION may result in this condition.
MeSH_Name: Consciousness Disorders
NUI: N0000000840
RxNorm_CUI: 1031236
UMLS_CUI: C0009792
code: C1858
imported from: NDF-RT.owl

Constipation [Disease/Finding]
type: Class
subclass of: Signs and Symptoms, Digestive [Disease/Finding]
type: NamedIndividual
Display_Name: Constipation
MeSH_CUI: M0005043
MeSH_DUI: D003248
MeSH_Definition: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
MeSH_Name: Constipation
NUI: N0000000841
RxNorm_CUI: 1022104
SNOMED_CID: 14760008
UMLS_CUI: C0009806
code: C1860
imported from: NDF-RT.owl

Cryoglobulinemia [Disease/Finding]
type: Class
subclass of: Paraproteinemias [Disease/Finding]
subclass of: Hemostatic Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Cryoglobulinemia
MeSH_CUI: M0005376
MeSH_DUI: D003449
MeSH_Definition: A condition characterized by the presence of abnormal quantities of CRYOGLOBULINS in the blood. Upon cold exposure, these abnormal proteins precipitate into the microvasculature leading to restricted blood flow in the exposed areas.
MeSH_Name: Cryoglobulinemia
NUI: N0000000879
RxNorm_CUI: 1027021
SNOMED_CID: 30911005
UMLS_CUI: C0010403
code: C1936
imported from: NDF-RT.owl

Cryptosporidiosis [Disease/Finding]
type: Class
subclass of: Coccidiosis [Disease/Finding]
subclass of: Intestinal Diseases, Parasitic [Disease/Finding]
subclass of: Protozoan Infections, Animal [Disease/Finding]
type: NamedIndividual
Display_Name: Cryptosporidiosis
MeSH_CUI: M0005385
MeSH_DUI: D003457
MeSH_Definition: Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.
MeSH_Name: Cryptosporidiosis
NUI: N0000000882
RxNorm_CUI: 1026025
SNOMED_CID: 240370009
SNOMED_CID: 58777003
UMLS_CUI: C0010418
code: C1942
imported from: NDF-RT.owl

Deglutition Disorders [Disease/Finding]
type: Class
subclass of: Esophageal Diseases [Disease/Finding]
subclass of: Pharyngeal Diseases [Disease/Finding]
Display_Name: Deglutition Disorders
MeSH_CUI: M0005756
MeSH_DUI: D003680
MeSH_Definition: Difficulty in SWALLOWING which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the PHARYNX and UPPER ESOPHAGEAL SPHINCTER; and esophageal dysphagia due to malfunction of the ESOPHAGUS.
MeSH_Name: Deglutition Disorders
NUI: N0000000910
RxNorm_CUI: 1023938
SNOMED_CID: 40739000
Synonym: Dysphagia
Synonym: Swallowing Disorders
UMLS_CUI: C0011168
code: C1998
imported from: NDF-RT.owl

Hepatitis D [Disease/Finding]
type: Class
subclass of: Hepatitis, Viral, Human [Disease/Finding]
subclass of: RNA Virus Infections [Disease/Finding]
Display_Name: Hepatitis D
MeSH_CUI: M0005790
MeSH_DUI: D003699
MeSH_Definition: INFLAMMATION of the LIVER in humans caused by HEPATITIS DELTA VIRUS, a defective RNA virus that can only infect HEPATITIS B patients. For its viral coating, hepatitis delta virus requires the HEPATITIS B SURFACE ANTIGENS produced by these patients. Hepatitis D can occur either concomitantly with (coinfection) or subsequent to (superinfection) hepatitis B infection. Similar to hepatitis B, it is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
MeSH_Name: Hepatitis D
NUI: N0000000913
RxNorm_CUI: 1023265
Synonym: Delta Hepatitis
Synonym: Delta Infection
Synonym: Hepatitis, Delta
Synonym: Infection, Delta
UMLS_CUI: C0011226
code: C2004
imported from: NDF-RT.owl

Demyelinating Diseases [Disease/Finding]
type: Class
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Demyelinating Diseases
MeSH_CUI: M0005825
MeSH_DUI: D003711
MeSH_Definition: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
MeSH_Name: Demyelinating Diseases
NUI: N0000000915
RxNorm_CUI: 1026682
Synonym: Demyelinating Disorders
UMLS_CUI: C0011303
code: C2008
imported from: NDF-RT.owl

Depressive Disorder [Disease/Finding]
type: Class
subclass of: Mood Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Depressive Disorder
MeSH_CUI: M0006033
MeSH_DUI: D003866
MeSH_Definition: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
MeSH_Name: Depressive Disorder
NUI: N0000000938
RxNorm_CUI: 1026289
SNOMED_CID: 35489007
Synonym: Neurosis, Depressive
UMLS_CUI: C0011581
code: C2054
imported from: NDF-RT.owl

Diarrhea [Disease/Finding]
type: Class
subclass of: Signs and Symptoms, Digestive [Disease/Finding]
type: NamedIndividual
Display_Name: Diarrhea
MeSH_CUI: M0006212
MeSH_DUI: D003967
MeSH_Definition: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
MeSH_Name: Diarrhea
NUI: N0000000963
RxNorm_CUI: 1022243
SNOMED_CID: 267060006
SNOMED_CID: 398032003
SNOMED_CID: 62315008
UMLS_CUI: C0011991
code: C2104
imported from: NDF-RT.owl

Digestive System Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Digestive System Diseases
MeSH_CUI: M0006374
MeSH_DUI: D004066
MeSH_Definition: Diseases in any part of the GASTROINTESTINAL TRACT or the accessory organs (LIVER; BILIARY TRACT; PANCREAS).
MeSH_Name: Digestive System Diseases
NUI: N0000000973
RxNorm_CUI: 1023342
SNOMED_CID: 53619000
UMLS_CUI: C0012242
code: C2124
imported from: NDF-RT.owl

Digestive System Neoplasms [Disease/Finding]
type: Class
subclass of: Digestive System Diseases [Disease/Finding]
subclass of: Neoplasms by Site [Disease/Finding]
Display_Name: Digestive System Neoplasms
MeSH_CUI: M0006375
MeSH_DUI: D004067
MeSH_Definition: Tumors or cancer of the DIGESTIVE SYSTEM.
MeSH_Name: Digestive System Neoplasms
NUI: N0000000974
RxNorm_CUI: 1027801
SNOMED_CID: 128348002
SNOMED_CID: 128415001
SNOMED_CID: 189527000
Synonym: Neoplasms, Digestive System
UMLS_CUI: C0012243
code: C2126
imported from: NDF-RT.owl

DNA Virus Infections [Disease/Finding]
type: Class
subclass of: DOID 934
Display_Name: DNA Virus Infections
MeSH_CUI: M0006675
MeSH_DUI: D004266
MeSH_Name: DNA Virus Infections
NUI: N0000000993
RxNorm_CUI: 1027612
Synonym: Infections, DNA Virus
UMLS_CUI: C0012922
code: C2164
imported from: NDF-RT.owl

Drug Hypersensitivity [Disease/Finding]
type: Class
subclass of: Hypersensitivity [Disease/Finding]
type: NamedIndividual
Display_Name: Drug Hypersensitivity
MeSH_CUI: M0006829
MeSH_DUI: D004342
MeSH_Definition: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
MeSH_Name: Drug Hypersensitivity
NUI: N0000000999
RxNorm_CUI: 1024684
SNOMED_CID: 416093006
SNOMED_CID: 416098002
Synonym: Allergy, Drug
Synonym: Drug Allergy
Synonym: Hypersensitivity, Drug
UMLS_CUI: C0013182
code: C2176
imported from: NDF-RT.owl

Drug Toxicity [Disease/Finding]
type: Class
subclass of: Poisoning [Disease/Finding]
type: NamedIndividual
Display_Name: Drug Toxicity
MeSH_CUI: M0006855
MeSH_DUI: D004362
MeSH_Definition: Manifestations of the adverse effects of drugs administered therapeutically or in the course of diagnostic techniques. It does not include accidental or intentional poisoning for which specific headings are available.
MeSH_Name: Drug Toxicity
NUI: N0000001000
RxNorm_CUI: 1022029
SNOMED_CID: 7895008
Synonym: Toxicity, Drug
UMLS_CUI: C0013221
code: C2178
imported from: NDF-RT.owl

Duodenal Diseases [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Duodenal Diseases
MeSH_CUI: M0006881
MeSH_DUI: D004378
MeSH_Definition: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).
MeSH_Name: Duodenal Diseases
NUI: N0000001005
RxNorm_CUI: 1022796
SNOMED_CID: 52182008
UMLS_CUI: C0013289
code: C2188
imported from: NDF-RT.owl

Dysentery [Disease/Finding]
type: Class
subclass of: Gastroenteritis [Disease/Finding]
subclass of: Intestinal Diseases [Disease/Finding]
Display_Name: Dysentery
MeSH_CUI: M0006913
MeSH_DUI: D004403
MeSH_Definition: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.
MeSH_Name: Dysentery
NUI: N0000001016
RxNorm_CUI: 1022956
SNOMED_CID: 111939009
SNOMED_CID: 19213003
SNOMED_CID: 236076004
Synonym: Infectious Diarrheal Disease
UMLS_CUI: C0013369
code: C2210
imported from: NDF-RT.owl

Dysentery, Bacillary [Disease/Finding]
type: Class
subclass of: Dysentery [Disease/Finding]
subclass of: Enterobacteriaceae Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Dysentery, Bacillary
MeSH_CUI: M0006916
MeSH_DUI: D004405
MeSH_Definition: DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest).
MeSH_Name: Dysentery, Bacillary
NUI: N0000001018
RxNorm_CUI: 1027736
SNOMED_CID: 274081004
UMLS_CUI: C1527298
code: C2214
imported from: NDF-RT.owl

Ear Diseases [Disease/Finding]
type: Class
subclass of: Otorhinolaryngologic Diseases [Disease/Finding]
Display_Name: Ear Diseases
MeSH_CUI: M0006941
MeSH_DUI: D004427
MeSH_Definition: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
MeSH_Name: Ear Diseases
NUI: N0000001036
RxNorm_CUI: 986705
SNOMED_CID: 25906001
Synonym: Otologic Diseases
Synonym: Otological Diseases
UMLS_CUI: C0013447
code: C2250
imported from: NDF-RT.owl

Ectoparasitic Infestations [Disease/Finding]
type: Class
subclass of: Skin Diseases, Parasitic [Disease/Finding]
Display_Name: Ectoparasitic Infestations
MeSH_CUI: M0007037
MeSH_DUI: D004478
MeSH_Definition: Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.
MeSH_Name: Ectoparasitic Infestations
NUI: N0000001051
RxNorm_CUI: 1029036
UMLS_CUI: C0013578
code: C2280
imported from: NDF-RT.owl

Elephantiasis [Disease/Finding]
type: Class
subclass of: Lymphedema [Disease/Finding]
type: NamedIndividual
Display_Name: Elephantiasis
MeSH_CUI: M0007229
MeSH_DUI: D004604
MeSH_Definition: Hypertrophy and thickening of the tissues from any cause. Elephantiasis caused by filarial infection is ELEPHANTIASIS, FILARIAL. (From Dorland, 27th ed)
MeSH_Name: Elephantiasis
NUI: N0000001062
RxNorm_CUI: 1029275
SNOMED_CID: 240820001
UMLS_CUI: C0013882
code: C2302
imported from: NDF-RT.owl

Encephalitis [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
subclass of: Central Nervous System Viral Diseases [Disease/Finding]
Display_Name: Encephalitis
MeSH_CUI: M0007337
MeSH_DUI: D004660
MeSH_Definition: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
MeSH_Name: Encephalitis
NUI: N0000001076
RxNorm_CUI: 1022474
SNOMED_CID: 45170000
Synonym: Brain Inflammation
Synonym: Inflammation, Brain
UMLS_CUI: C0014038
code: C2330
imported from: NDF-RT.owl

Encephalitis, Arbovirus [Disease/Finding]
type: Class
subclass of: Arbovirus Infections [Disease/Finding]
subclass of: RNA Virus Infections [Disease/Finding]
subclass of: Encephalitis, Viral [Disease/Finding]
Display_Name: Encephalitis, Arbovirus
MeSH_CUI: M0007356
MeSH_DUI: D004671
MeSH_Definition: Infections of the brain caused by arthropod-borne viruses (i.e., arboviruses) primarily from the families TOGAVIRIDAE; FLAVIVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; and RHABDOVIRIDAE. Life cycles of these viruses are characterized by ZOONOSES, with birds and lower mammals serving as intermediate hosts. The virus is transmitted to humans by the bite of mosquitoes (CULICIDAE) or TICKS. Clinical manifestations include fever, headache, alterations of mentation, focal neurologic deficits, and COMA. (From Clin Microbiol Rev 1994 Jan;7(1):89-116; Walton, Brain's Diseases of the Nervous System, 10th ed, p321)
MeSH_Name: Encephalitis, Arbovirus
NUI: N0000001078
RxNorm_CUI: 1021779
SNOMED_CID: 186498004
SNOMED_CID: 192687008
SNOMED_CID: 285756005
Synonym: Arthropod-Borne Encephalitis
Synonym: Arthropod-Borne Viral Encephalitis
Synonym: Encephalitis, Arthropod-Borne
Synonym: Encephalitis, Epidemic
Synonym: Epidemic Encephalitis
Synonym: Viral Encephalitis, Arthropod-Borne
UMLS_CUI: C0014055
code: C2334
imported from: NDF-RT.owl

Endocarditis [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
Display_Name: Endocarditis
MeSH_CUI: M0007392
MeSH_DUI: D004696
MeSH_Definition: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
MeSH_Name: Endocarditis
NUI: N0000001096
RxNorm_CUI: 1027251
SNOMED_CID: 56819008
UMLS_CUI: C0014118
code: C2370
imported from: NDF-RT.owl

Endocarditis, Bacterial [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
subclass of: Endocarditis [Disease/Finding]
subclass of: Cardiovascular Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Endocarditis, Bacterial
MeSH_CUI: M0007393
MeSH_DUI: D004697
MeSH_Definition: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
MeSH_Name: Endocarditis, Bacterial
NUI: N0000001097
RxNorm_CUI: 1021809
SNOMED_CID: 301183007
Synonym: Bacterial Endocarditides
Synonym: Bacterial Endocarditis
Synonym: Endocarditides, Bacterial
UMLS_CUI: C0014121
code: C2372
imported from: NDF-RT.owl

Endocrine System Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Endocrine System Diseases
MeSH_CUI: M0007396
MeSH_DUI: D004700
MeSH_Definition: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
MeSH_Name: Endocrine System Diseases
NUI: N0000001099
RxNorm_CUI: 1022080
SNOMED_CID: 362969004
Synonym: Diseases of Endocrine System
Synonym: Endocrine Diseases
UMLS_CUI: C0014130
code: C2376
imported from: NDF-RT.owl

Endocrine Gland Neoplasms [Disease/Finding]
type: Class
subclass of: Endocrine System Diseases [Disease/Finding]
subclass of: Neoplasms by Site [Disease/Finding]
Display_Name: Endocrine Gland Neoplasms
MeSH_CUI: M0007397
MeSH_DUI: D004701
MeSH_Definition: Tumors or cancer of the ENDOCRINE GLANDS.
MeSH_Name: Endocrine Gland Neoplasms
NUI: N0000001100
RxNorm_CUI: 1022324
SNOMED_CID: 387922007
SNOMED_CID: 387927001
Synonym: Neoplasms, Endocrine Gland
UMLS_CUI: C0014132
code: C2378
imported from: NDF-RT.owl

Endometriosis [Disease/Finding]
type: Class
subclass of: Genital Diseases, Female [Disease/Finding]
type: NamedIndividual
Display_Name: Endometriosis
MeSH_CUI: M0007413
MeSH_DUI: D004715
MeSH_Definition: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
MeSH_Name: Endometriosis
NUI: N0000001102
RxNorm_CUI: 1024249
SNOMED_CID: 129103003
UMLS_CUI: C0014175
code: C2382
imported from: NDF-RT.owl

Enterobacteriaceae Infections [Disease/Finding]
type: Class
subclass of: Gram-Negative Bacterial Infections [Disease/Finding]
Display_Name: Enterobacteriaceae Infections
MeSH_CUI: M0007472
MeSH_DUI: D004756
MeSH_Definition: Infections with bacteria of the family ENTEROBACTERIACEAE.
MeSH_Name: Enterobacteriaceae Infections
NUI: N0000001108
RxNorm_CUI: 1024436
Synonym: Enterobacterial Infections
Synonym: Infections, Enterobacteriaceae
Synonym: Infections, Enterobacterial
UMLS_CUI: C0014347
code: C2394
imported from: NDF-RT.owl

Enterocolitis [Disease/Finding]
type: Class
subclass of: Gastroenteritis [Disease/Finding]
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Enterocolitis
MeSH_CUI: M0007478
MeSH_DUI: D004760
MeSH_Definition: Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.
MeSH_Name: Enterocolitis
NUI: N0000001109
RxNorm_CUI: 1025705
SNOMED_CID: 43752006
UMLS_CUI: C0014356
code: C2396
imported from: NDF-RT.owl

Enterocolitis, Pseudomembranous [Disease/Finding]
type: Class
subclass of: Clostridium Infections [Disease/Finding]
subclass of: Enterocolitis [Disease/Finding]
type: NamedIndividual
Display_Name: Enterocolitis, Pseudomembranous
MeSH_CUI: M0007479
MeSH_DUI: D004761
MeSH_Definition: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
MeSH_Name: Enterocolitis, Pseudomembranous
NUI: N0000001110
RxNorm_CUI: 1025680
SNOMED_CID: 397683000
Synonym: Pseudomembranous Enterocolitis
UMLS_CUI: C0014358
code: C2398
imported from: NDF-RT.owl

Eosinophilia [Disease/Finding]
type: Class
subclass of: Leukocyte Disorders [Disease/Finding]
Display_Name: Eosinophilia
MeSH_CUI: M0007532
MeSH_DUI: D004802
MeSH_Definition: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
MeSH_Name: Eosinophilia
NUI: N0000001115
RxNorm_CUI: 1021800
SNOMED_CID: 191363000
UMLS_CUI: C0014457
code: C2408
imported from: NDF-RT.owl

Epilepsy [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Epilepsy
MeSH_CUI: M0007564
MeSH_DUI: D004827
MeSH_Definition: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
MeSH_Name: Epilepsy
NUI: N0000001126
RxNorm_CUI: 1021750
SNOMED_CID: 128613002
SNOMED_CID: 84757009
Synonym: Epileptic Seizures
Synonym: Seizure Disorder
Synonym: Seizures, Epileptic
UMLS_CUI: C0014544
code: C2430
imported from: NDF-RT.owl

Esophageal Achalasia [Disease/Finding]
type: Class
subclass of: Esophageal Motility Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Esophageal Achalasia
MeSH_CUI: M0007740
MeSH_DUI: D004931
MeSH_Definition: A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus).
MeSH_Name: Esophageal Achalasia
NUI: N0000001155
RxNorm_CUI: 1023001
SNOMED_CID: 235630008
SNOMED_CID: 45564002
Synonym: Achalasia
Synonym: Achalasia, Esophageal
Synonym: Cardiospasm
UMLS_CUI: C0014848
code: C2488
imported from: NDF-RT.owl

Esophageal Diseases [Disease/Finding]
type: Class
subclass of: Gastrointestinal Diseases [Disease/Finding]
Display_Name: Esophageal Diseases
MeSH_CUI: M0007747
MeSH_DUI: D004935
MeSH_Definition: Pathological processes in the ESOPHAGUS.
MeSH_Name: Esophageal Diseases
NUI: N0000001159
RxNorm_CUI: 990942
SNOMED_CID: 37657006
UMLS_CUI: C0014852
code: C2496
imported from: NDF-RT.owl

Eye Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Eye Diseases
MeSH_CUI: M0008088
MeSH_DUI: D005128
MeSH_Name: Eye Diseases
NUI: N0000001181
RxNorm_CUI: 1023594
SNOMED_CID: 194183009
UMLS_CUI: C0015397
code: C2540
imported from: NDF-RT.owl

Facial Dermatoses [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Facial Dermatoses
MeSH_CUI: M0008112
MeSH_DUI: D005148
MeSH_Name: Facial Dermatoses
NUI: N0000001190
RxNorm_CUI: 1028247
Synonym: Facial Dermatosis
UMLS_CUI: C0015456
code: C2558
imported from: NDF-RT.owl

Fascioloidiasis [Disease/Finding]
type: Class
subclass of: Helminthiasis, Animal [Disease/Finding]
subclass of: Trematode Infections [Disease/Finding]
Display_Name: Fascioloidiasis
MeSH_CUI: M0008246
MeSH_DUI: D005213
MeSH_Definition: Infection of cattle and other herbivores with the giant liver fluke Fascioloides magna. It is characterized by extensive destruction of the liver parenchyma.
MeSH_Name: Fascioloidiasis
NUI: N0000001214
RxNorm_CUI: 1026508
UMLS_CUI: C0015655
code: C2606
imported from: NDF-RT.owl

Fatty Liver [Disease/Finding]
type: Class
subclass of: Liver Diseases [Disease/Finding]
Display_Name: Fatty Liver
MeSH_CUI: M0008275
MeSH_DUI: D005234
MeSH_Definition: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
MeSH_Name: Fatty Liver
NUI: N0000001217
RxNorm_CUI: 1022768
SNOMED_CID: 197321007
SNOMED_CID: 371330000
UMLS_CUI: C0015695
code: C2612
imported from: NDF-RT.owl

Female Urogenital Diseases and Pregnancy Complications [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Female Urogenital Diseases and Pregnancy Complications
MeSH_CUI: M0008309
MeSH_DUI: D005261
MeSH_Definition: Pathological processes of the female URINARY TRACT, the reproductive system (GENITALIA, FEMALE), and disorders related to PREGNANCY.
MeSH_Name: Female Urogenital Diseases and Pregnancy Complications
NUI: N0000001224
RxNorm_CUI: 985609
UMLS_CUI: C1720765
code: C2626
imported from: NDF-RT.owl

Filariasis [Disease/Finding]
type: Class
subclass of: Spirurida Infections [Disease/Finding]
Display_Name: Filariasis
MeSH_CUI: M0008468
MeSH_DUI: D005368
MeSH_Definition: Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
MeSH_Name: Filariasis
NUI: N0000001254
RxNorm_CUI: 1023733
SNOMED_CID: 105706003
Synonym: Filarioidea Infections
Synonym: Infections, Filarioidea
UMLS_CUI: C0016085
code: C2686
imported from: NDF-RT.owl

Gastroenteritis [Disease/Finding]
type: Class
subclass of: Gastrointestinal Diseases [Disease/Finding]
Display_Name: Gastroenteritis
MeSH_CUI: M0009018
MeSH_DUI: D005759
MeSH_Definition: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
MeSH_Name: Gastroenteritis
NUI: N0000001317
RxNorm_CUI: 1024672
SNOMED_CID: 25374005
UMLS_CUI: C0017160
code: C2812
imported from: NDF-RT.owl

Gastrointestinal Diseases [Disease/Finding]
type: Class
subclass of: Digestive System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Gastrointestinal Diseases
MeSH_CUI: M0009033
MeSH_DUI: D005767
MeSH_Definition: Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
MeSH_Name: Gastrointestinal Diseases
NUI: N0000001320
RxNorm_CUI: 1022118
SNOMED_CID: 119292006
UMLS_CUI: C0017178
code: C2818
imported from: NDF-RT.owl

Gastrointestinal Neoplasms [Disease/Finding]
type: Class
subclass of: Digestive System Neoplasms [Disease/Finding]
subclass of: Gastrointestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Gastrointestinal Neoplasms
MeSH_CUI: M0009038
MeSH_DUI: D005770
MeSH_Definition: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
MeSH_Name: Gastrointestinal Neoplasms
NUI: N0000001321
RxNorm_CUI: 1025588
SNOMED_CID: 126768004
Synonym: Neoplasms, Gastrointestinal
UMLS_CUI: C0017185
code: C2820
imported from: NDF-RT.owl

Genital Diseases, Female [Disease/Finding]
type: Class
subclass of: Female Urogenital Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Genital Diseases, Female
MeSH_CUI: M0009154
MeSH_DUI: D005831
MeSH_Definition: Pathological processes involving the female reproductive tract (GENITALIA, FEMALE).
MeSH_Name: Genital Diseases, Female
NUI: N0000001323
RxNorm_CUI: 1026095
SNOMED_CID: 244938009
SNOMED_CID: 310789003
Synonym: Female Genital Diseases
Synonym: Gynecologic Diseases
UMLS_CUI: C0017411
code: C2824
imported from: NDF-RT.owl

Genital Diseases, Male [Disease/Finding]
type: Class
subclass of: Male Urogenital Diseases [Disease/Finding]
Display_Name: Genital Diseases, Male
MeSH_CUI: M0009155
MeSH_DUI: D005832
MeSH_Definition: Pathological processes involving the male reproductive tract (GENITALIA, MALE).
MeSH_Name: Genital Diseases, Male
NUI: N0000001324
RxNorm_CUI: 1021837
SNOMED_CID: 64557000
Synonym: Male Genital Diseases
UMLS_CUI: C0017412
code: C2826
imported from: NDF-RT.owl

Genital Neoplasms, Female [Disease/Finding]
type: Class
subclass of: Urogenital Neoplasms [Disease/Finding]
Display_Name: Genital Neoplasms, Female
MeSH_CUI: M0009156
MeSH_DUI: D005833
MeSH_Definition: Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
MeSH_Name: Genital Neoplasms, Female
NUI: N0000001325
RxNorm_CUI: 1024023
SNOMED_CID: 126907002
Synonym: Female Genital Neoplasms
Synonym: Gynecologic Neoplasms
Synonym: Neoplasms, Female Genital
Synonym: Neoplasms, Gynecologic
UMLS_CUI: C0017416
code: C2828
imported from: NDF-RT.owl

Giardiasis [Disease/Finding]
type: Class
subclass of: Intestinal Diseases, Parasitic [Disease/Finding]
subclass of: Protozoan Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Giardiasis
MeSH_CUI: M0009224
MeSH_DUI: D005873
MeSH_Definition: An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA LAMBLIA. It is spread via contaminated food and water and by direct person-to-person contact.
MeSH_Name: Giardiasis
NUI: N0000001331
RxNorm_CUI: 988685
SNOMED_CID: 10679007
SNOMED_CID: 58265007
Synonym: Lambliasis
UMLS_CUI: C0017536
code: C2840
imported from: NDF-RT.owl

Glomerulonephritis [Disease/Finding]
type: Class
subclass of: Nephritis [Disease/Finding]
Display_Name: Glomerulonephritis
MeSH_CUI: M0009300
MeSH_DUI: D005921
MeSH_Definition: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.
MeSH_Name: Glomerulonephritis
NUI: N0000001351
RxNorm_CUI: 1021985
SNOMED_CID: 236391006
SNOMED_CID: 36171008
UMLS_CUI: C0017658
code: C2880
imported from: NDF-RT.owl

Glomerulosclerosis, Focal Segmental [Disease/Finding]
type: Class
subclass of: Glomerulonephritis [Disease/Finding]
type: NamedIndividual
Display_Name: Glomerulosclerosis, Focal Segmental
MeSH_CUI: M0009302
MeSH_DUI: D005923
MeSH_Definition: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
MeSH_Name: Glomerulosclerosis, Focal Segmental
NUI: N0000001353
RxNorm_CUI: 1026699
SNOMED_CID: 25821008
Synonym: Focal Segmental Glomerulosclerosis
Synonym: Glomerulonephritis, Focal Sclerosing
Synonym: Glomerulosclerosis, Focal
UMLS_CUI: C0017668
code: C2884
imported from: NDF-RT.owl

Gonadal Disorders [Disease/Finding]
type: Class
subclass of: Endocrine System Diseases [Disease/Finding]
Display_Name: Gonadal Disorders
MeSH_CUI: M0009536
MeSH_DUI: D006058
MeSH_Definition: Pathological processes of the OVARIES or the TESTES.
MeSH_Name: Gonadal Disorders
NUI: N0000001376
RxNorm_CUI: 986338
UMLS_CUI: C0018050
code: C2930
imported from: NDF-RT.owl

Graft vs Host Disease [Disease/Finding]
type: Class
subclass of: Immune System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Graft vs Host Disease
MeSH_CUI: M0009578
MeSH_DUI: D006086
MeSH_Definition: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
MeSH_Name: Graft vs Host Disease
NUI: N0000001384
RxNorm_CUI: 1024721
SNOMED_CID: 234646005
Synonym: Graft-Versus-Host Disease
Synonym: Graft-vs-Host Disease
Synonym: Homologous Wasting Disease
Synonym: Runt Disease
UMLS_CUI: C0018133
code: C2946
imported from: NDF-RT.owl

Gynecomastia [Disease/Finding]
type: Class
subclass of: Breast Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Gynecomastia
MeSH_CUI: M0009717
MeSH_DUI: D006177
MeSH_Definition: Enlargement of the BREAST in the males, caused by an excess of ESTROGENS. Physiological gynecomastia is normally observed in NEWBORNS; ADOLESCENT; and AGING males.
MeSH_Name: Gynecomastia
NUI: N0000001396
RxNorm_CUI: 1022299
SNOMED_CID: 4754008
Synonym: Male Breast Enlargement
UMLS_CUI: C0018418
code: C2970
imported from: NDF-RT.owl

Haemophilus Infections [Disease/Finding]
type: Class
subclass of: Pasteurellaceae Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Haemophilus Infections
MeSH_CUI: M0009740
MeSH_DUI: D006192
MeSH_Definition: Infections with bacteria of the genus HAEMOPHILUS.
MeSH_Name: Haemophilus Infections
NUI: N0000001398
RxNorm_CUI: 1021899
SNOMED_CID: 41659003
Synonym: Hemophilus Infections
Synonym: Infections, Haemophilus
Synonym: Infections, Hemophilus
UMLS_CUI: C0018482
code: C2974
imported from: NDF-RT.owl

Heart Block [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
type: NamedIndividual
Display_Name: Heart Block
MeSH_CUI: M0009945
MeSH_DUI: D006327
MeSH_Definition: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
MeSH_Name: Heart Block
NUI: N0000001430
RxNorm_CUI: 1023276
SNOMED_CID: 233916004
UMLS_CUI: C0018794
code: C3038
imported from: NDF-RT.owl

Heart Defects, Congenital [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
subclass of: Cardiovascular Abnormalities [Disease/Finding]
type: NamedIndividual
Display_Name: Heart Defects, Congenital
MeSH_CUI: M0009950
MeSH_DUI: D006330
MeSH_Definition: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
MeSH_Name: Heart Defects, Congenital
NUI: N0000001431
RxNorm_CUI: 1022077
SNOMED_CID: 204413006
Synonym: Abnormality, Heart
Synonym: Congenital Heart Defect
Synonym: Congenital Heart Defects
Synonym: Defects, Congenital Heart
Synonym: Heart Abnormalities
Synonym: Heart Defect, Congenital
UMLS_CUI: C0018798
code: C3040
imported from: NDF-RT.owl

Heart Diseases [Disease/Finding]
type: Class
subclass of: Cardiovascular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Heart Diseases
MeSH_CUI: M0009951
MeSH_DUI: D006331
MeSH_Definition: Pathological conditions involving the HEART including its structural and functional abnormalities.
MeSH_Name: Heart Diseases
NUI: N0000001432
RxNorm_CUI: 1022072
SNOMED_CID: 56265001
Synonym: Cardiac Diseases
UMLS_CUI: C0018799
code: C3042
imported from: NDF-RT.owl

Heart Failure [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Heart Failure
MeSH_CUI: M0009953
MeSH_DUI: D006333
MeSH_Definition: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
MeSH_Name: Heart Failure
NUI: N0000001434
RxNorm_CUI: 1024953
SNOMED_CID: 42343007
Synonym: Cardiac Failure
UMLS_CUI: C0018802
code: C3046
imported from: NDF-RT.owl

Heart Valve Diseases [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
Display_Name: Heart Valve Diseases
MeSH_CUI: M0009972
MeSH_DUI: D006349
MeSH_Definition: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
MeSH_Name: Heart Valve Diseases
NUI: N0000001443
RxNorm_CUI: 989613
SNOMED_CID: 368009
Synonym: Valvular Heart Diseases
UMLS_CUI: C0018824
code: C3064
imported from: NDF-RT.owl

Helminthiasis [Disease/Finding]
type: Class
subclass of: Parasitic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Helminthiasis
MeSH_CUI: M0010007
MeSH_DUI: D006373
MeSH_Definition: Infestation with parasitic worms of the helminth class.
MeSH_Name: Helminthiasis
NUI: N0000001448
RxNorm_CUI: 1021865
SNOMED_CID: 27601005
UMLS_CUI: C0018889
code: C3074
imported from: NDF-RT.owl

Helminthiasis, Animal [Disease/Finding]
type: Class
subclass of: Helminthiasis [Disease/Finding]
subclass of: Parasitic Diseases, Animal [Disease/Finding]
Display_Name: Helminthiasis, Animal
MeSH_CUI: M0010009
MeSH_DUI: D006374
MeSH_Definition: Infestation of animals with parasitic worms of the helminth class. The infestation may be experimental or veterinary.
MeSH_Name: Helminthiasis, Animal
NUI: N0000001449
RxNorm_CUI: 1028354
UMLS_CUI: C0018891
code: C3076
imported from: NDF-RT.owl

Hemangioma [Disease/Finding]
type: Class
subclass of: Neoplasms, Vascular Tissue [Disease/Finding]
type: NamedIndividual
Display_Name: Hemangioma
MeSH_CUI: M0010031
MeSH_DUI: D006391
MeSH_Definition: A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
MeSH_Name: Hemangioma
NUI: N0000001451
RxNorm_CUI: 987582
SNOMED_CID: 189194008
SNOMED_CID: 400210000
UMLS_CUI: C0018916
code: C3080
imported from: NDF-RT.owl

Hematologic Diseases [Disease/Finding]
type: Class
subclass of: Hemic and Lymphatic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Hematologic Diseases
MeSH_CUI: M0010044
MeSH_DUI: D006402
MeSH_Definition: Disorders of the blood and blood forming tissues.
MeSH_Name: Hematologic Diseases
NUI: N0000001459
RxNorm_CUI: 1021953
SNOMED_CID: 191402006
SNOMED_CID: 267573000
Synonym: Blood Diseases
Synonym: Hematological Diseases
UMLS_CUI: C0018939
code: C3096
imported from: NDF-RT.owl

Hemic and Lymphatic Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Hemic and Lymphatic Diseases
MeSH_CUI: M0010072
MeSH_DUI: D006425
MeSH_Definition: Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHROCYTE AGGREGATION, INTRAVASCULAR) and chemical components (e.g., BLOOD PROTEIN DISORDERS); lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes.
MeSH_Name: Hemic and Lymphatic Diseases
NUI: N0000001466
RxNorm_CUI: 1026878
UMLS_CUI: C0018981
code: C3110
imported from: NDF-RT.owl

Hemoglobinopathies [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
subclass of: Genetic Diseases, Inborn [Disease/Finding]
type: NamedIndividual
Display_Name: Hemoglobinopathies
MeSH_CUI: M0010129
MeSH_DUI: D006453
MeSH_Definition: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
MeSH_Name: Hemoglobinopathies
NUI: N0000001472
RxNorm_CUI: 1023547
SNOMED_CID: 80141007
UMLS_CUI: C0019045
code: C3122
imported from: NDF-RT.owl

Hemorrhage [Disease/Finding]
type: Class
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Hemorrhage
MeSH_CUI: M0010152
MeSH_DUI: D006470
MeSH_Definition: Bleeding or escape of blood from a vessel.
MeSH_Name: Hemorrhage
NUI: N0000001481
RxNorm_CUI: 1023287
SNOMED_CID: 195511004
Synonym: Bleeding
UMLS_CUI: C0019080
code: C3140
imported from: NDF-RT.owl

Hemorrhagic Disorders [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Hemorrhagic Disorders
MeSH_CUI: M0010157
MeSH_DUI: D006474
MeSH_Definition: Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a structural flaw in the blood vessels (HEMOSTATIC DISORDERS).
MeSH_Name: Hemorrhagic Disorders
NUI: N0000001485
RxNorm_CUI: 1023732
SNOMED_CID: 191331006
Synonym: Hemorrhagic Diathesis
UMLS_CUI: C0019087
code: C3148
imported from: NDF-RT.owl

Hepatitis [Disease/Finding]
type: Class
subclass of: Liver Diseases [Disease/Finding]
Display_Name: Hepatitis
MeSH_CUI: M0010205
MeSH_DUI: D006505
MeSH_Definition: INFLAMMATION of the LIVER.
MeSH_Name: Hepatitis
NUI: N0000001499
RxNorm_CUI: 989819
SNOMED_CID: 128241005
SNOMED_CID: 197351001
UMLS_CUI: C0019158
code: C3176
imported from: NDF-RT.owl

Hepatitis, Chronic [Disease/Finding]
type: Class
subclass of: Hepatitis [Disease/Finding]
Display_Name: Hepatitis, Chronic
MeSH_CUI: M0010227
MeSH_DUI: D006521
MeSH_Definition: INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors.
MeSH_Name: Hepatitis, Chronic
NUI: N0000001504
RxNorm_CUI: 989540
SNOMED_CID: 197286002
SNOMED_CID: 197288001
SNOMED_CID: 76783007
Synonym: Chronic Hepatitis
UMLS_CUI: C0019189
code: C3186
imported from: NDF-RT.owl

Hepatitis, Viral, Human [Disease/Finding]
type: Class
subclass of: Hepatitis [Disease/Finding]
subclass of: DOID 934
Display_Name: Hepatitis, Viral, Human
MeSH_CUI: M0010233
MeSH_DUI: D006525
MeSH_Definition: INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).
MeSH_Name: Hepatitis, Viral, Human
NUI: N0000001508
RxNorm_CUI: 990781
UMLS_CUI: C0019195
code: C3194
imported from: NDF-RT.owl

Hepatitis C [Disease/Finding]
type: Class
subclass of: Hepatitis, Viral, Human [Disease/Finding]
subclass of: Flaviviridae Infections [Disease/Finding]
Display_Name: Hepatitis C
MeSH_CUI: M0010234
MeSH_DUI: D006526
MeSH_Definition: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
MeSH_Name: Hepatitis C
NUI: N0000001509
RxNorm_CUI: 1024879
SNOMED_CID: 186634008
SNOMED_CID: 50711007
Synonym: Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
Synonym: PT-NANBH
Synonym: Parenterally-Transmitted Non-A, Non-B Hepatitis
UMLS_CUI: C0019196
code: C3196
imported from: NDF-RT.owl

Carcinoma, Hepatocellular [Disease/Finding]
type: Class
subclass of: Adenocarcinoma [Disease/Finding]
subclass of: Liver Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: Carcinoma, Hepatocellular
MeSH_CUI: M0010236
MeSH_DUI: D006528
MeSH_Definition: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
MeSH_Name: Carcinoma, Hepatocellular
NUI: N0000001511
RxNorm_CUI: 1021881
SNOMED_CID: 109841003
SNOMED_CID: 187769009
Synonym: Hepatocellular Cancer
Synonym: Hepatocellular Carcinoma
Synonym: Hepatoma
Synonym: Liver Cancer, Adult
Synonym: Liver Cell Carcinoma, Adult
UMLS_CUI: C2239176
code: C3200
imported from: NDF-RT.owl

Herpes Labialis [Disease/Finding]
type: Class
subclass of: Herpes Simplex [Disease/Finding]
subclass of: Lip Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Herpes Labialis
MeSH_CUI: M0010278
MeSH_DUI: D006560
MeSH_Definition: Herpes simplex, caused by type 1 virus, primarily spread by oral secretions and usually occurring as a concomitant of fever. It may also develop in the absence of fever or prior illness. It commonly involves the facial region, especially the lips and the nares. (Dorland, 27th ed.)
MeSH_Name: Herpes Labialis
NUI: N0000001529
RxNorm_CUI: 1021986
SNOMED_CID: 1475003
Synonym: Cold Sore
Synonym: Fever Blister
Synonym: Herpes Simplex, Labial
UMLS_CUI: C0019345
code: C3236
imported from: NDF-RT.owl

Herpes Simplex [Disease/Finding]
type: Class
subclass of: Herpesviridae Infections [Disease/Finding]
subclass of: Skin Diseases, Viral [Disease/Finding]
Display_Name: Herpes Simplex
MeSH_CUI: M0010279
MeSH_DUI: D006561
MeSH_Definition: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
MeSH_Name: Herpes Simplex
NUI: N0000001530
RxNorm_CUI: 1023866
SNOMED_CID: 88594005
UMLS_CUI: C0019348
code: C3238
imported from: NDF-RT.owl

Herpesviridae Infections [Disease/Finding]
type: Class
subclass of: DNA Virus Infections [Disease/Finding]
Display_Name: Herpesviridae Infections
MeSH_CUI: M0010285
MeSH_DUI: D006566
MeSH_Definition: Virus diseases caused by the HERPESVIRIDAE.
MeSH_Name: Herpesviridae Infections
NUI: N0000001533
RxNorm_CUI: 1024733
SNOMED_CID: 23513009
Synonym: Herpesvirus Infections
Synonym: Infections, Herpesviridae
Synonym: Infections, Herpesvirus
UMLS_CUI: C0019372
code: C3244
imported from: NDF-RT.owl

Hiccup [Disease/Finding]
type: Class
subclass of: Signs and Symptoms, Digestive [Disease/Finding]
type: NamedIndividual
Display_Name: Hiccup
MeSH_CUI: M0010343
MeSH_DUI: D006606
MeSH_Definition: A spasm of the diaphragm that causes a sudden inhalation followed by rapid closure of the glottis which produces a sound.
MeSH_Name: Hiccup
NUI: N0000001534
RxNorm_CUI: 1021801
SNOMED_CID: 65958008
Synonym: Hiccough
UMLS_CUI: C0019521
code: C3246
imported from: NDF-RT.owl

Hypersensitivity [Disease/Finding]
type: Class
subclass of: Immune System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Hypersensitivity
MeSH_CUI: M0010851
MeSH_DUI: D006967
MeSH_Definition: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
MeSH_Name: Hypersensitivity
NUI: N0000001610
RxNorm_CUI: 1022134
SNOMED_CID: 106190000
SNOMED_CID: 127072000
SNOMED_CID: 269284003
Synonym: Allergy
UMLS_CUI: C0020517
code: C3398
imported from: NDF-RT.owl

Hypersensitivity, Immediate [Disease/Finding]
type: Class
subclass of: Hypersensitivity [Disease/Finding]
type: NamedIndividual
Display_Name: Hypersensitivity, Immediate
MeSH_CUI: M0010854
MeSH_DUI: D006969
MeSH_Definition: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
MeSH_Name: Hypersensitivity, Immediate
NUI: N0000001612
RxNorm_CUI: 1023968
SNOMED_CID: 20671006
Synonym: Atopic Hypersensitivity
Synonym: Hypersensitivity, Atopic
Synonym: Hypersensitivity, Type I
Synonym: IgE-Mediated Hypersensitivity
Synonym: Type I Hypersensitivity
UMLS_CUI: C0020523
code: C3402
imported from: NDF-RT.owl

Hypertension [Disease/Finding]
type: Class
subclass of: Vascular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Hypertension
MeSH_CUI: M0010859
MeSH_DUI: D006973
MeSH_Definition: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
MeSH_Name: Hypertension
NUI: N0000001616
RxNorm_CUI: 1023354
SNOMED_CID: 38341003
Synonym: Blood Pressure, High
UMLS_CUI: C0020538
code: C3410
imported from: NDF-RT.owl

Hypotension [Disease/Finding]
type: Class
subclass of: Vascular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Hypotension
MeSH_CUI: M0010927
MeSH_DUI: D007022
MeSH_Definition: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
MeSH_Name: Hypotension
NUI: N0000001649
RxNorm_CUI: 1022536
SNOMED_CID: 45007003
Synonym: Blood Pressure, Low
Synonym: Hypotension, Vascular
Synonym: Low Blood Pressure
Synonym: Vascular Hypotension
UMLS_CUI: C0020649
code: C3476
imported from: NDF-RT.owl

Ileal Diseases [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
Display_Name: Ileal Diseases
MeSH_CUI: M0011023
MeSH_DUI: D007077
MeSH_Definition: Pathological development in the ILEUM including the ILEOCECAL VALVE.
MeSH_Name: Ileal Diseases
NUI: N0000001660
RxNorm_CUI: 1025763
UMLS_CUI: C0020875
code: C3498
imported from: NDF-RT.owl

Ileal Neoplasms [Disease/Finding]
type: Class
subclass of: Ileal Diseases [Disease/Finding]
subclass of: Intestinal Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: Ileal Neoplasms
MeSH_CUI: M0011024
MeSH_DUI: D007078
MeSH_Definition: Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).
MeSH_Name: Ileal Neoplasms
NUI: N0000001661
RxNorm_CUI: 1026955
SNOMED_CID: 126835002
UMLS_CUI: C0020876
code: C3500
imported from: NDF-RT.owl

Immunologic Deficiency Syndromes [Disease/Finding]
type: Class
subclass of: Immune System Diseases [Disease/Finding]
Display_Name: Immunologic Deficiency Syndromes
MeSH_CUI: M0011155
MeSH_DUI: D007153
MeSH_Definition: Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral.
MeSH_Name: Immunologic Deficiency Syndromes
NUI: N0000001667
RxNorm_CUI: 1022772
SNOMED_CID: 191005003
SNOMED_CID: 234532001
Synonym: Deficiency Syndrome, Immunologic
Synonym: Deficiency Syndromes, Immunologic
Synonym: Immunologic Deficiency Syndrome
Synonym: Immunological Deficiency Syndromes
UMLS_CUI: C0021051
code: C3512
imported from: NDF-RT.owl

Immune System Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Immune System Diseases
MeSH_CUI: M0011156
MeSH_DUI: D007154
MeSH_Definition: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.
MeSH_Name: Immune System Diseases
NUI: N0000001668
RxNorm_CUI: 1022843
SNOMED_CID: 41266007
Synonym: Diseases of Immune System
Synonym: Immune Diseases
Synonym: Immune Disorders
Synonym: Immunologic Diseases
Synonym: Immunological Diseases
UMLS_CUI: C0021053
code: C3514
imported from: NDF-RT.owl

Immunoproliferative Disorders [Disease/Finding]
type: Class
subclass of: Immune System Diseases [Disease/Finding]
Display_Name: Immunoproliferative Disorders
MeSH_CUI: M0011164
MeSH_DUI: D007160
MeSH_Definition: Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins.
MeSH_Name: Immunoproliferative Disorders
NUI: N0000001669
RxNorm_CUI: 1028023
SNOMED_CID: 127071007
UMLS_CUI: C0021070
code: C3516
imported from: NDF-RT.owl

Infection [Disease/Finding]
type: Class
subclass of: Bacterial Infections and Mycoses [Disease/Finding]
type: NamedIndividual
Display_Name: Infection
MeSH_CUI: M0011294
MeSH_DUI: D007239
MeSH_Definition: Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
MeSH_Name: Infection
NUI: N0000001681
RxNorm_CUI: 1022093
SNOMED_CID: 40733004
UMLS_CUI: C0021311
code: C3540
imported from: NDF-RT.owl

Inflammation [Disease/Finding]
type: Class
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Inflammation
MeSH_CUI: M0011307
MeSH_DUI: D007249
MeSH_Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
MeSH_Name: Inflammation
NUI: N0000001687
RxNorm_CUI: 987778
SNOMED_CID: 23583003
UMLS_CUI: C0021368
code: C3552
imported from: NDF-RT.owl

Intestinal Diseases [Disease/Finding]
type: Class
subclass of: Gastrointestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Intestinal Diseases
MeSH_CUI: M0011569
MeSH_DUI: D007410
MeSH_Definition: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
MeSH_Name: Intestinal Diseases
NUI: N0000001698
RxNorm_CUI: 1023320
SNOMED_CID: 85919009
UMLS_CUI: C0021831
code: C3574
imported from: NDF-RT.owl

Intestinal Diseases, Parasitic [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
subclass of: Parasitic Diseases [Disease/Finding]
Display_Name: Intestinal Diseases, Parasitic
MeSH_CUI: M0011570
MeSH_DUI: D007411
MeSH_Definition: Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
MeSH_Name: Intestinal Diseases, Parasitic
NUI: N0000001699
RxNorm_CUI: 1021992
SNOMED_CID: 87282003
Synonym: Parasitic Intestinal Diseases
UMLS_CUI: C0021832
code: C3576
imported from: NDF-RT.owl

Intestinal Neoplasms [Disease/Finding]
type: Class
subclass of: Gastrointestinal Neoplasms [Disease/Finding]
subclass of: Intestinal Diseases [Disease/Finding]
Display_Name: Intestinal Neoplasms
MeSH_CUI: M0011574
MeSH_DUI: D007414
MeSH_Definition: Tumors or cancer of the INTESTINES.
MeSH_Name: Intestinal Neoplasms
NUI: N0000001701
RxNorm_CUI: 1023921
SNOMED_CID: 126769007
Synonym: Intestines Neoplasms
Synonym: Neoplasms, Intestinal
UMLS_CUI: C0021841
code: C3580
imported from: NDF-RT.owl

Intestinal Obstruction [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Intestinal Obstruction
MeSH_CUI: M0011575
MeSH_DUI: D007415
MeSH_Definition: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.
MeSH_Name: Intestinal Obstruction
NUI: N0000001702
RxNorm_CUI: 1023737
SNOMED_CID: 81060008
UMLS_CUI: C0021843
code: C3582
imported from: NDF-RT.owl

Joint Diseases [Disease/Finding]
type: Class
subclass of: Musculoskeletal Diseases [Disease/Finding]
Display_Name: Joint Diseases
MeSH_CUI: M0011860
MeSH_DUI: D007592
MeSH_Name: Joint Diseases
NUI: N0000001727
RxNorm_CUI: 1022553
SNOMED_CID: 399269003
UMLS_CUI: C0022408
code: C3632
imported from: NDF-RT.owl

Kidney Diseases [Disease/Finding]
type: Class
subclass of: Urologic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Kidney Diseases
MeSH_CUI: M0012014
MeSH_DUI: D007674
MeSH_Definition: Pathological processes of the KIDNEY or its component tissues.
MeSH_Name: Kidney Diseases
NUI: N0000001748
RxNorm_CUI: 1022215
SNOMED_CID: 90708001
UMLS_CUI: C0022658
code: C3674
imported from: NDF-RT.owl

Kidney Neoplasms [Disease/Finding]
type: Class
subclass of: Kidney Diseases [Disease/Finding]
subclass of: Urologic Neoplasms [Disease/Finding]
Display_Name: Kidney Neoplasms
MeSH_CUI: M0012021
MeSH_DUI: D007680
MeSH_Definition: Tumors or cancers of the KIDNEY.
MeSH_Name: Kidney Neoplasms
NUI: N0000001751
RxNorm_CUI: 1026062
SNOMED_CID: 126880001
Synonym: Neoplasms, Kidney
Synonym: Renal Neoplasms
UMLS_CUI: C0022665
code: C3680
imported from: NDF-RT.owl

Labyrinth Diseases [Disease/Finding]
type: Class
subclass of: Ear Diseases [Disease/Finding]
Display_Name: Labyrinth Diseases
MeSH_CUI: M0012125
MeSH_DUI: D007759
MeSH_Definition: Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).
MeSH_Name: Labyrinth Diseases
NUI: N0000001772
RxNorm_CUI: 1025984
SNOMED_CID: 20425006
Synonym: Inner Ear Disease
UMLS_CUI: C0022890
code: C3722
imported from: NDF-RT.owl

Leukemia [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Leukemia
MeSH_CUI: M0012382
MeSH_DUI: D007938
MeSH_Definition: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
MeSH_Name: Leukemia
NUI: N0000001815
RxNorm_CUI: 1021987
SNOMED_CID: 188762002
SNOMED_CID: 93143009
UMLS_CUI: C0023418
code: C3808
imported from: NDF-RT.owl

Leukemia, Hairy Cell [Disease/Finding]
type: Class
subclass of: Leukemia [Disease/Finding]
subclass of: Lymphoproliferative Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Leukemia, Hairy Cell
MeSH_CUI: M0012387
MeSH_DUI: D007943
MeSH_Definition: A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
MeSH_Name: Leukemia, Hairy Cell
NUI: N0000001820
RxNorm_CUI: 1022561
SNOMED_CID: 118613001
SNOMED_CID: 188644003
Synonym: Hairy Cell Leukemia
Synonym: Leukemic Reticuloendotheliosis
Synonym: Reticuloendotheliosis, Leukemic
UMLS_CUI: C0023443
code: C3818
imported from: NDF-RT.owl

Leukemia, Myeloid [Disease/Finding]
type: Class
subclass of: Leukemia [Disease/Finding]
Display_Name: Leukemia, Myeloid
MeSH_CUI: M0012396
MeSH_DUI: D007951
MeSH_Definition: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
MeSH_Name: Leukemia, Myeloid
NUI: N0000001826
RxNorm_CUI: 1023661
SNOMED_CID: 188732008
Synonym: Granulocytic Leukemia
Synonym: Leukemia, Granulocytic
Synonym: Leukemia, Myelocytic
Synonym: Leukemia, Myelogenous
Synonym: Myelocytic Leukemia
Synonym: Myelogenous Leukemia
Synonym: Myeloid Leukemia
UMLS_CUI: C0023470
code: C3830
imported from: NDF-RT.owl

Leukocyte Disorders [Disease/Finding]
type: Class
subclass of: Hematologic Diseases [Disease/Finding]
Display_Name: Leukocyte Disorders
MeSH_CUI: M0012409
MeSH_DUI: D007960
MeSH_Definition: Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells.
MeSH_Name: Leukocyte Disorders
NUI: N0000001831
RxNorm_CUI: 1025909
SNOMED_CID: 54097007
UMLS_CUI: C0023510
code: C3840
imported from: NDF-RT.owl

Lip Diseases [Disease/Finding]
type: Class
subclass of: Mouth Diseases [Disease/Finding]
Display_Name: Lip Diseases
MeSH_CUI: M0012537
MeSH_DUI: D008047
MeSH_Name: Lip Diseases
NUI: N0000001846
RxNorm_CUI: 1022975
SNOMED_CID: 90678009
UMLS_CUI: C0023760
code: C3870
imported from: NDF-RT.owl

Liver Diseases [Disease/Finding]
type: Class
subclass of: Digestive System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Liver Diseases
MeSH_CUI: M0012644
MeSH_DUI: D008107
MeSH_Definition: Pathological processes of the LIVER.
MeSH_Name: Liver Diseases
NUI: N0000001866
RxNorm_CUI: 1024220
SNOMED_CID: 235856003
UMLS_CUI: C0023895
code: C3910
imported from: NDF-RT.owl

Liver Neoplasms [Disease/Finding]
type: Class
subclass of: Digestive System Neoplasms [Disease/Finding]
subclass of: Liver Diseases [Disease/Finding]
Display_Name: Liver Neoplasms
MeSH_CUI: M0012652
MeSH_DUI: D008113
MeSH_Definition: Tumors or cancer of the LIVER.
MeSH_Name: Liver Neoplasms
NUI: N0000001869
RxNorm_CUI: 1025382
SNOMED_CID: 126851005
Synonym: Hepatic Neoplasms
Synonym: Neoplasms, Hepatic
Synonym: Neoplasms, Liver
UMLS_CUI: C0023903
code: C3916
imported from: NDF-RT.owl

Lung Diseases [Disease/Finding]
type: Class
subclass of: Respiratory Tract Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Lung Diseases
MeSH_CUI: M0012744
MeSH_DUI: D008171
MeSH_Definition: Pathological processes involving any part of the LUNG.
MeSH_Name: Lung Diseases
NUI: N0000001879
RxNorm_CUI: 1021971
SNOMED_CID: 19829001
Synonym: Disease, Pulmonary
Synonym: Diseases, Pulmonary
Synonym: Pulmonary Disease
Synonym: Pulmonary Diseases
UMLS_CUI: C0024115
code: C3936
imported from: NDF-RT.owl

Lupus Erythematosus, Cutaneous [Disease/Finding]
type: Class
subclass of: Connective Tissue Diseases [Disease/Finding]
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Lupus Erythematosus, Cutaneous
MeSH_CUI: M0012754
MeSH_DUI: D008178
MeSH_Definition: A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= LUPUS ERYTHEMATOSUS, SYSTEMIC with skin lesions), subacute, and chronic (= LUPUS ERYTHEMATOSUS, DISCOID).
MeSH_Name: Lupus Erythematosus, Cutaneous
NUI: N0000001885
RxNorm_CUI: 1027393
SNOMED_CID: 7119001
UMLS_CUI: C0024137
code: C3948
imported from: NDF-RT.owl

Lupus Erythematosus, Discoid [Disease/Finding]
type: Class
subclass of: Lupus Erythematosus, Cutaneous [Disease/Finding]
type: NamedIndividual
Display_Name: Lupus Erythematosus, Discoid
MeSH_CUI: M0012756
MeSH_DUI: D008179
MeSH_Definition: A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
MeSH_Name: Lupus Erythematosus, Discoid
NUI: N0000001886
RxNorm_CUI: 1022154
SNOMED_CID: 200938002
SNOMED_CID: 238927000
Synonym: Lupus Erythematosus, Chronic Cutaneous
Synonym: Lupus Erythematosus, Cutaneous, Chronic
UMLS_CUI: C0024138
code: C3950
imported from: NDF-RT.owl

Lupus Erythematosus, Systemic [Disease/Finding]
type: Class
subclass of: Autoimmune Diseases [Disease/Finding]
subclass of: Connective Tissue Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Lupus Erythematosus, Systemic
MeSH_CUI: M0012757
MeSH_DUI: D008180
MeSH_Definition: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
MeSH_Name: Lupus Erythematosus, Systemic
NUI: N0000001887
RxNorm_CUI: 1023595
SNOMED_CID: 55464009
Synonym: Lupus Erythematosus Disseminatus
Synonym: Systemic Lupus Erythematosus
UMLS_CUI: C0024141
code: C3952
imported from: NDF-RT.owl

Lymphatic Diseases [Disease/Finding]
type: Class
subclass of: Hemic and Lymphatic Diseases [Disease/Finding]
Display_Name: Lymphatic Diseases
MeSH_CUI: M0012792
MeSH_DUI: D008206
MeSH_Definition: Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.
MeSH_Name: Lymphatic Diseases
NUI: N0000001898
RxNorm_CUI: 1024043
SNOMED_CID: 111590001
SNOMED_CID: 234087005
SNOMED_CID: 362971004
UMLS_CUI: C0024228
code: C3974
imported from: NDF-RT.owl

Lymphedema [Disease/Finding]
type: Class
subclass of: Lymphatic Diseases [Disease/Finding]
Display_Name: Lymphedema
MeSH_CUI: M0012800
MeSH_DUI: D008209
MeSH_Definition: Edema due to obstruction of lymph vessels or disorders of the lymph nodes.
MeSH_Name: Lymphedema
NUI: N0000001900
RxNorm_CUI: 1023978
SNOMED_CID: 234097001
UMLS_CUI: C0024236
code: C3978
imported from: NDF-RT.owl

Lymphoma [Disease/Finding]
type: Class
subclass of: Lymphoproliferative Disorders [Disease/Finding]
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Lymphoma
MeSH_CUI: M0012817
MeSH_DUI: D008223
MeSH_Definition: A general term for various neoplastic diseases of the lymphoid tissue.
MeSH_Name: Lymphoma
NUI: N0000001905
RxNorm_CUI: 1024259
SNOMED_CID: 118600007
Synonym: Germinoblastoma
Synonym: Lymphoma, Malignant
Synonym: Reticulolymphosarcoma
Synonym: Sarcoma, Germinoblastic
UMLS_CUI: C0024299
code: C3988
imported from: NDF-RT.owl

Lymphoma, Non-Hodgkin [Disease/Finding]
type: Class
subclass of: Lymphoma [Disease/Finding]
Display_Name: Lymphoma, Non-Hodgkin
MeSH_CUI: M0012822
MeSH_DUI: D008228
MeSH_Definition: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
MeSH_Name: Lymphoma, Non-Hodgkin
NUI: N0000001910
RxNorm_CUI: 1024301
SNOMED_CID: 118601006
Synonym: Diffuse Small Cleaved-Cell Lymphoma
Synonym: Lymphoma, Atypical Diffuse Small Lymphoid
Synonym: Lymphoma, Non-Hodgkin's
Synonym: Lymphoma, Non-Hodgkins
Synonym: Lymphoma, Nonhodgkin's
Synonym: Lymphoma, Nonhodgkins
Synonym: Lymphoma, Small Cleaved Cell, Diffuse
Synonym: Lymphoma, Small Cleaved-Cell, Diffuse
Synonym: Non-Hodgkin Lymphoma
Synonym: Non-Hodgkin's Lymphoma
Synonym: Small Cleaved-Cell Lymphoma, Diffuse
UMLS_CUI: C0024305
code: C3998
imported from: NDF-RT.owl

Lymphoproliferative Disorders [Disease/Finding]
type: Class
subclass of: Immunoproliferative Disorders [Disease/Finding]
subclass of: Lymphatic Diseases [Disease/Finding]
Display_Name: Lymphoproliferative Disorders
MeSH_CUI: M0012826
MeSH_DUI: D008232
MeSH_Definition: Disorders characterized by proliferation of lymphoid tissue, general or unspecified.
MeSH_Name: Lymphoproliferative Disorders
NUI: N0000001914
RxNorm_CUI: 987016
SNOMED_CID: 277466009
Synonym: Duncan's Syndrome
UMLS_CUI: C0024314
code: C4006
imported from: NDF-RT.owl

Macular Degeneration [Disease/Finding]
type: Class
subclass of: Retinal Degeneration [Disease/Finding]
type: NamedIndividual
Display_Name: Macular Degeneration
MeSH_CUI: M0012875
MeSH_DUI: D008268
MeSH_Definition: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
MeSH_Name: Macular Degeneration
NUI: N0000001918
RxNorm_CUI: 987866
SNOMED_CID: 302891003
Synonym: Age-Related Macular Degeneration
Synonym: Age-Related Maculopathies
Synonym: Age-Related Maculopathy
Synonym: Macular Dystrophy
Synonym: Maculopathies, Age-Related
Synonym: Maculopathy, Age-Related
UMLS_CUI: C0242383
code: C4014
imported from: NDF-RT.owl

Malaria [Disease/Finding]
type: Class
subclass of: Protozoan Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Malaria
MeSH_CUI: M0012910
MeSH_DUI: D008288
MeSH_Definition: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
MeSH_Name: Malaria
NUI: N0000001924
RxNorm_CUI: 1025176
SNOMED_CID: 105649009
SNOMED_CID: 186797008
SNOMED_CID: 61462000
Synonym: Infections, Plasmodium
Synonym: Marsh Fever
Synonym: Paludism
Synonym: Plasmodium Infections
Synonym: Remittent Fever
UMLS_CUI: C0024530
code: C4026
imported from: NDF-RT.owl

Malaria, Avian [Disease/Finding]
type: Class
subclass of: Malaria [Disease/Finding]
type: NamedIndividual
Display_Name: Malaria, Avian
MeSH_CUI: M0012911
MeSH_DUI: D008289
MeSH_Definition: Any of a group of infections of fowl caused by protozoa of the genera PLASMODIUM, Leucocytozoon, and Haemoproteus. The life cycles of these parasites and the disease produced bears strong resemblance to those observed in human malaria.
MeSH_Name: Malaria, Avian
NUI: N0000001925
RxNorm_CUI: 1024199
SNOMED_CID: 1498006
UMLS_CUI: C0024533
code: C4028
imported from: NDF-RT.owl

Mansonelliasis [Disease/Finding]
type: Class
subclass of: Filariasis [Disease/Finding]
type: NamedIndividual
Display_Name: Mansonelliasis
MeSH_CUI: M0013012
MeSH_DUI: D008368
MeSH_Definition: Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.
MeSH_Name: Mansonelliasis
NUI: N0000001941
RxNorm_CUI: 1025658
SNOMED_CID: 240849009
Synonym: Mansonellosis
UMLS_CUI: C0024759
code: C4060
imported from: NDF-RT.owl

Melanoma [Disease/Finding]
type: Class
subclass of: Nevi and Melanomas [Disease/Finding]
subclass of: Neuroendocrine Tumors [Disease/Finding]
type: NamedIndividual
Display_Name: Melanoma
MeSH_CUI: M0013309
MeSH_DUI: D008545
MeSH_Definition: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
MeSH_Name: Melanoma
NUI: N0000001969
RxNorm_CUI: 1023577
SNOMED_CID: 372244006
Synonym: Malignant Melanoma
UMLS_CUI: C0025202
code: C4116
imported from: NDF-RT.owl

Menstruation Disturbances [Disease/Finding]
type: Class
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Menstruation Disturbances
MeSH_CUI: M0013402
MeSH_DUI: D008599
MeSH_Definition: Variations of menstruation which may be indicative of disease.
MeSH_Name: Menstruation Disturbances
NUI: N0000001994
RxNorm_CUI: 1021753
SNOMED_CID: 386804004
Synonym: Menstruation Disorders
UMLS_CUI: C0025345
code: C4166
imported from: NDF-RT.owl

Metabolic Diseases [Disease/Finding]
type: Class
subclass of: Nutritional and Metabolic Diseases [Disease/Finding]
Display_Name: Metabolic Diseases
MeSH_CUI: M0013493
MeSH_DUI: D008659
MeSH_Definition: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
MeSH_Name: Metabolic Diseases
NUI: N0000002004
RxNorm_CUI: 1022778
SNOMED_CID: 30390004
SNOMED_CID: 75934005
Synonym: Diseases, Metabolic
Synonym: Thesaurismosis
UMLS_CUI: C0025517
code: C4186
imported from: NDF-RT.owl

Metabolism, Inborn Errors [Disease/Finding]
type: Class
subclass of: Metabolic Diseases [Disease/Finding]
subclass of: Genetic Diseases, Inborn [Disease/Finding]
Display_Name: Metabolism, Inborn Errors
MeSH_CUI: M0013496
MeSH_DUI: D008661
MeSH_Definition: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
MeSH_Name: Metabolism, Inborn Errors
NUI: N0000002005
RxNorm_CUI: 1024978
SNOMED_CID: 86095007
Synonym: Inborn Errors of Metabolism
Synonym: Metabolism Errors, Inborn
UMLS_CUI: C0025521
code: C4188
imported from: NDF-RT.owl

Mite Infestations [Disease/Finding]
type: Class
subclass of: Ectoparasitic Infestations [Disease/Finding]
Display_Name: Mite Infestations
MeSH_CUI: M0013932
MeSH_DUI: D008924
MeSH_Definition: Infestations with arthropods of the subclass ACARI, superorder Acariformes.
MeSH_Name: Mite Infestations
NUI: N0000002018
RxNorm_CUI: 1022195
SNOMED_CID: 187214007
SNOMED_CID: 240885009
Synonym: Acariasis
UMLS_CUI: C0026229
code: C4214
imported from: NDF-RT.owl

Motion Sickness [Disease/Finding]
type: Class
subclass of: Signs and Symptoms [Disease/Finding]
type: NamedIndividual
Display_Name: Motion Sickness
MeSH_CUI: M0014105
MeSH_DUI: D009041
MeSH_Definition: Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting and dizziness.
MeSH_Name: Motion Sickness
NUI: N0000002031
RxNorm_CUI: 1022871
SNOMED_CID: 269278001
SNOMED_CID: 37031009
UMLS_CUI: C0026603
code: C4240
imported from: NDF-RT.owl

Stomatognathic Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Stomatognathic Diseases
MeSH_CUI: M0014128
MeSH_DUI: D009057
MeSH_Definition: General or unspecified diseases of the stomatognathic system, comprising the mouth, teeth, jaws, and pharynx.
MeSH_Name: Stomatognathic Diseases
NUI: N0000002034
RxNorm_CUI: 1027350
Synonym: Mouth and Tooth Diseases
UMLS_CUI: C0038368
code: C4246
imported from: NDF-RT.owl

Mouth Diseases [Disease/Finding]
type: Class
subclass of: Stomatognathic Diseases [Disease/Finding]
Display_Name: Mouth Diseases
MeSH_CUI: M0014130
MeSH_DUI: D009059
MeSH_Name: Mouth Diseases
NUI: N0000002036
RxNorm_CUI: 1027441
SNOMED_CID: 118938008
UMLS_CUI: C0026636
code: C4250
imported from: NDF-RT.owl

Movement Disorders [Disease/Finding]
type: Class
subclass of: Central Nervous System Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Movement Disorders
MeSH_CUI: M0014141
MeSH_DUI: D009069
MeSH_Definition: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
MeSH_Name: Movement Disorders
NUI: N0000002039
RxNorm_CUI: 1024614
SNOMED_CID: 60342002
Synonym: Dyskinesia Syndromes
Synonym: Movement Disorder Syndromes
UMLS_CUI: C0026650
code: C4256
imported from: NDF-RT.owl

Multiple Myeloma [Disease/Finding]
type: Class
subclass of: Lymphoproliferative Disorders [Disease/Finding]
subclass of: Paraproteinemias [Disease/Finding]
subclass of: Hemostatic Disorders [Disease/Finding]
subclass of: Neoplasms, Plasma Cell [Disease/Finding]
type: NamedIndividual
Display_Name: Multiple Myeloma
MeSH_CUI: M0014195
MeSH_DUI: D009101
MeSH_Definition: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
MeSH_Name: Multiple Myeloma
NUI: N0000002050
RxNorm_CUI: 1022141
SNOMED_CID: 109989006
Synonym: Kahler Disease
Synonym: Myeloma, Plasma-Cell
Synonym: Myeloma-Multiple
Synonym: Myelomatosis
Synonym: Plasma Cell Myeloma
UMLS_CUI: C0026764
code: C4278
imported from: NDF-RT.owl

Multiple Sclerosis [Disease/Finding]
type: Class
subclass of: Demyelinating Autoimmune Diseases, CNS [Disease/Finding]
type: NamedIndividual
Display_Name: Multiple Sclerosis
MeSH_CUI: M0014197
MeSH_DUI: D009103
MeSH_Definition: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
MeSH_Name: Multiple Sclerosis
NUI: N0000002052
RxNorm_CUI: 1024685
SNOMED_CID: 192928003
SNOMED_CID: 24700007
Synonym: MS (Multiple Sclerosis)
Synonym: Sclerosis, Disseminated
UMLS_CUI: C0026769
code: C4282
imported from: NDF-RT.owl

Musculoskeletal Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Musculoskeletal Diseases
MeSH_CUI: M0014259
MeSH_DUI: D009140
MeSH_Definition: Diseases of the muscles and their associated ligaments and other connective tissue and of the bones and cartilage viewed collectively.
MeSH_Name: Musculoskeletal Diseases
NUI: N0000002067
RxNorm_CUI: 1022076
SNOMED_CID: 928000
UMLS_CUI: C0026857
code: C4312
imported from: NDF-RT.owl

Myasthenia Gravis [Disease/Finding]
type: Class
subclass of: Autoimmune Diseases of the Nervous System [Disease/Finding]
subclass of: Neuromuscular Junction Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Myasthenia Gravis
MeSH_CUI: M0014279
MeSH_DUI: D009157
MeSH_Definition: A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
MeSH_Name: Myasthenia Gravis
NUI: N0000002070
RxNorm_CUI: 1024161
SNOMED_CID: 91637004
UMLS_CUI: C0026896
code: C4318
imported from: NDF-RT.owl

Mycobacterium Infections [Disease/Finding]
type: Class
subclass of: Actinomycetales Infections [Disease/Finding]
Display_Name: Mycobacterium Infections
MeSH_CUI: M0014287
MeSH_DUI: D009164
MeSH_Definition: Infections with bacteria of the genus MYCOBACTERIUM.
MeSH_Name: Mycobacterium Infections
NUI: N0000002071
RxNorm_CUI: 1022908
SNOMED_CID: 88415009
Synonym: Infections, Mycobacterium
UMLS_CUI: C0026918
code: C4320
imported from: NDF-RT.owl

Mycobacterium Infections, Atypical [Disease/Finding]
type: Class
subclass of: Mycobacterium Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Mycobacterium Infections, Atypical
MeSH_CUI: M0014288
MeSH_DUI: D009165
MeSH_Definition: Infections with so called atypical mycobacteria (tuberculoid bacilli): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae.
MeSH_Name: Mycobacterium Infections, Atypical
NUI: N0000002072
RxNorm_CUI: 1026349
SNOMED_CID: 111811007
SNOMED_CID: 111812000
Synonym: Atypical Mycobacterium Infections
Synonym: Infections, Atypical Mycobacterium
Synonym: Infections, Tuberculoid
Synonym: Tuberculoid Infections
UMLS_CUI: C0026919
code: C4322
imported from: NDF-RT.owl

Mycoplasma Infections [Disease/Finding]
type: Class
subclass of: Mycoplasmatales Infections [Disease/Finding]
Display_Name: Mycoplasma Infections
MeSH_CUI: M0014307
MeSH_DUI: D009175
MeSH_Definition: Infections with species of the genus MYCOPLASMA.
MeSH_Name: Mycoplasma Infections
NUI: N0000002073
RxNorm_CUI: 1023539
SNOMED_CID: 186462007
SNOMED_CID: 186464008
Synonym: Infections, Mycoplasma
UMLS_CUI: C0026936
code: C4324
imported from: NDF-RT.owl

Mycoplasmatales Infections [Disease/Finding]
type: Class
subclass of: Gram-Negative Bacterial Infections [Disease/Finding]
Display_Name: Mycoplasmatales Infections
MeSH_CUI: M0014312
MeSH_DUI: D009180
MeSH_Definition: Infections with bacteria of the order MYCOPLASMATALES.
MeSH_Name: Mycoplasmatales Infections
NUI: N0000002074
RxNorm_CUI: 1030047
Synonym: Infections, Mycoplasmatales
UMLS_CUI: C0026945
code: C4326
imported from: NDF-RT.owl

Mycoses [Disease/Finding]
type: Class
subclass of: Bacterial Infections and Mycoses [Disease/Finding]
Display_Name: Mycoses
MeSH_CUI: M0014313
MeSH_DUI: D009181
MeSH_Name: Mycoses
NUI: N0000002075
RxNorm_CUI: 1024676
SNOMED_CID: 3218000
Synonym: Fungus Diseases
UMLS_CUI: C0026946
code: C4328
imported from: NDF-RT.owl

Mycosis Fungoides [Disease/Finding]
type: Class
subclass of: Lymphoma, T-Cell, Cutaneous [Disease/Finding]
type: NamedIndividual
Display_Name: Mycosis Fungoides
MeSH_CUI: M0014314
MeSH_DUI: D009182
MeSH_Definition: A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected.
MeSH_Name: Mycosis Fungoides
NUI: N0000002076
RxNorm_CUI: 1024347
SNOMED_CID: 118618005
SNOMED_CID: 188618003
UMLS_CUI: C0026948
code: C4330
imported from: NDF-RT.owl

Myeloproliferative Disorders [Disease/Finding]
type: Class
subclass of: Bone Marrow Diseases [Disease/Finding]
Display_Name: Myeloproliferative Disorders
MeSH_CUI: M0014332
MeSH_DUI: D009196
MeSH_Definition: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
MeSH_Name: Myeloproliferative Disorders
NUI: N0000002082
RxNorm_CUI: 1022355
SNOMED_CID: 128925001
SNOMED_CID: 414792005
SNOMED_CID: 414794006
UMLS_CUI: C0027022
code: C4342
imported from: NDF-RT.owl

Myocardial Infarction [Disease/Finding]
type: Class
subclass of: Myocardial Ischemia [Disease/Finding]
type: NamedIndividual
Display_Name: Myocardial Infarction
MeSH_CUI: M0014340
MeSH_DUI: D009203
MeSH_Definition: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
MeSH_Name: Myocardial Infarction
NUI: N0000002085
RxNorm_CUI: 1024565
SNOMED_CID: 22298006
Synonym: Myocardial Infarct
UMLS_CUI: C0027051
code: C4348
imported from: NDF-RT.owl

Nausea [Disease/Finding]
type: Class
subclass of: Signs and Symptoms, Digestive [Disease/Finding]
type: NamedIndividual
Display_Name: Nausea
MeSH_CUI: M0014528
MeSH_DUI: D009325
MeSH_Definition: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
MeSH_Name: Nausea
NUI: N0000002114
RxNorm_CUI: 1023644
SNOMED_CID: 73879007
UMLS_CUI: C0027497
code: C4406
imported from: NDF-RT.owl

Nematode Infections [Disease/Finding]
type: Class
subclass of: Helminthiasis [Disease/Finding]
Display_Name: Nematode Infections
MeSH_CUI: M0014560
MeSH_DUI: D009349
MeSH_Definition: Infections by nematodes, general or unspecified.
MeSH_Name: Nematode Infections
NUI: N0000002119
RxNorm_CUI: 990406
SNOMED_CID: 84706005
Synonym: Infections, Nematode
UMLS_CUI: C0027583
code: C4416
imported from: NDF-RT.owl

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH_CUI: M0014570
MeSH_DUI: D009358
MeSH_Definition: Diseases existing at birth and often before birth, or that develop during the first month of life (INFANT, NEWBORN, DISEASES), regardless of causation. Of these diseases, those characterized by structural deformities are termed CONGENITAL ABNORMALITIES.
MeSH_Name: Congenital, Hereditary, and Neonatal Diseases and Abnormalities
NUI: N0000002121
RxNorm_CUI: 989203
UMLS_CUI: C0027612
code: C4420
imported from: NDF-RT.owl

Neoplasms [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Neoplasms
MeSH_CUI: M0014585
MeSH_DUI: D009369
MeSH_Definition: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
MeSH_Name: Neoplasms
NUI: N0000002128
RxNorm_CUI: 1022284
SNOMED_CID: 189525008
SNOMED_CID: 189526009
SNOMED_CID: 55342001
Synonym: Tumors
UMLS_CUI: C0027651
code: C4434
imported from: NDF-RT.owl

Neoplasms by Histologic Type [Disease/Finding]
type: Class
subclass of: Neoplasms [Disease/Finding]
Display_Name: Neoplasms by Histologic Type
MeSH_CUI: M0014588
MeSH_DUI: D009370
MeSH_Definition: A collective term for the various histological types of NEOPLASMS. It is more likely to be used by searchers than by indexers and catalogers.
MeSH_Name: Neoplasms by Histologic Type
NUI: N0000002129
RxNorm_CUI: 986146
Synonym: Histological Type of Neoplasm
Synonym: Histological Types of Neoplasms
Synonym: Neoplasms by Histological Type
UMLS_CUI: C0027652
code: C4436
imported from: NDF-RT.owl

Neoplasms by Site [Disease/Finding]
type: Class
subclass of: Neoplasms [Disease/Finding]
Display_Name: Neoplasms by Site
MeSH_CUI: M0014589
MeSH_DUI: D009371
MeSH_Definition: A collective term for precoordinated organ/neoplasm headings locating neoplasms by organ, as BRAIN NEOPLASMS; DUODENAL NEOPLASMS; LIVER NEOPLASMS; etc.
MeSH_Name: Neoplasms by Site
NUI: N0000002130
RxNorm_CUI: 1026659
Synonym: Neoplasms by Sites
Synonym: Site, Neoplasm
Synonym: Sites, Neoplasm
UMLS_CUI: C0027653
code: C4438
imported from: NDF-RT.owl

Neoplasms, Germ Cell and Embryonal [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Germ Cell and Embryonal
MeSH_CUI: M0014592
MeSH_DUI: D009373
MeSH_Definition: Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
MeSH_Name: Neoplasms, Germ Cell and Embryonal
NUI: N0000002132
RxNorm_CUI: 1026873
Synonym: Germ Cell and Embryonal Neoplasms
Synonym: Germ Cell and Embryonic Neoplasms
Synonym: Neoplasms, Germ Cell and Embryonic
UMLS_CUI: C0027658
code: C4442
imported from: NDF-RT.owl

Neoplasms, Experimental [Disease/Finding]
type: Class
subclass of: Neoplasms [Disease/Finding]
Display_Name: Neoplasms, Experimental
MeSH_CUI: M0014595
MeSH_DUI: D009374
MeSH_Definition: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
MeSH_Name: Neoplasms, Experimental
NUI: N0000002133
RxNorm_CUI: 1025199
Synonym: Experimental Neoplasms
UMLS_CUI: C0027659
code: C4444
imported from: NDF-RT.owl

Neoplasms, Glandular and Epithelial [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Glandular and Epithelial
MeSH_CUI: M0014596
MeSH_DUI: D009375
MeSH_Definition: Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.
MeSH_Name: Neoplasms, Glandular and Epithelial
NUI: N0000002134
RxNorm_CUI: 1028442
Synonym: Glandular and Epithelial Neoplasms
Synonym: Neoplasms, Glandular Epithelial
UMLS_CUI: C0027660
code: C4446
imported from: NDF-RT.owl

Neoplasms, Hormone-Dependent [Disease/Finding]
type: Class
subclass of: Neoplasms [Disease/Finding]
Display_Name: Neoplasms, Hormone-Dependent
MeSH_CUI: M0014599
MeSH_DUI: D009376
MeSH_Definition: Certain tumors that 1, arise in organs that are normally dependent on specific hormones and 2, are stimulated or caused to regress by manipulation of the endocrine environment.
MeSH_Name: Neoplasms, Hormone-Dependent
NUI: N0000002135
RxNorm_CUI: 1023294
Synonym: Hormone-Dependent Neoplasms
UMLS_CUI: C0027661
code: C4448
imported from: NDF-RT.owl

Neoplasms, Nerve Tissue [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Nerve Tissue
MeSH_CUI: M0014605
MeSH_DUI: D009380
MeSH_Definition: Neoplasms composed of nerve tissue. This concept does not refer to neoplasms located in the nervous system or its component nerves.
MeSH_Name: Neoplasms, Nerve Tissue
NUI: N0000002139
RxNorm_CUI: 985772
Synonym: Neoplasms, Nervous Tissue
Synonym: Nerve Tissue Neoplasms
Synonym: Nervous Tissue Neoplasms
UMLS_CUI: C0027665
code: C4456
imported from: NDF-RT.owl

Neoplasms, Vascular Tissue [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Vascular Tissue
MeSH_CUI: M0014610
MeSH_DUI: D009383
MeSH_Definition: Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.
MeSH_Name: Neoplasms, Vascular Tissue
NUI: N0000002142
RxNorm_CUI: 1023689
Synonym: Blood Vessel Tumors
Synonym: Vascular Tissue Neoplasms
UMLS_CUI: C0282607
code: C4462
imported from: NDF-RT.owl

Neoplastic Processes [Disease/Finding]
type: Class
subclass of: Neoplasms [Disease/Finding]
subclass of: Pathologic Processes [Disease/Finding]
Display_Name: Neoplastic Processes
MeSH_CUI: M0014612
MeSH_DUI: D009385
MeSH_Definition: The pathological mechanisms and forms taken by tissue during degeneration into a neoplasm and its subsequent activity.
MeSH_Name: Neoplastic Processes
NUI: N0000002144
RxNorm_CUI: 1026939
Synonym: Processes, Neoplastic
UMLS_CUI: C0027671
code: C4466
imported from: NDF-RT.owl

Nephritis [Disease/Finding]
type: Class
subclass of: Kidney Diseases [Disease/Finding]
Display_Name: Nephritis
MeSH_CUI: M0014626
MeSH_DUI: D009393
MeSH_Definition: Inflammation of any part of the KIDNEY.
MeSH_Name: Nephritis
NUI: N0000002147
RxNorm_CUI: 1022904
SNOMED_CID: 52845002
UMLS_CUI: C0027697
code: C4472
imported from: NDF-RT.owl

Nervous System Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Nervous System Diseases
MeSH_CUI: M0014667
MeSH_DUI: D009422
MeSH_Definition: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
MeSH_Name: Nervous System Diseases
NUI: N0000002159
RxNorm_CUI: 1026444
SNOMED_CID: 118940003
Synonym: Nervous System Disorders
Synonym: Neurologic Disorders
Synonym: Neurological Disorders
UMLS_CUI: C0027765
code: C4496
imported from: NDF-RT.owl

Nervous System Neoplasms [Disease/Finding]
type: Class
subclass of: Neoplasms by Site [Disease/Finding]
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Nervous System Neoplasms
MeSH_CUI: M0014668
MeSH_DUI: D009423
MeSH_Definition: Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.
MeSH_Name: Nervous System Neoplasms
NUI: N0000002160
RxNorm_CUI: 1024871
SNOMED_CID: 126950007
Synonym: Neoplasms, Nervous System
Synonym: Nervous System Tumors
Synonym: Tumors of the Nervous System
UMLS_CUI: C0027766
code: C4498
imported from: NDF-RT.owl

Neurologic Manifestations [Disease/Finding]
type: Class
subclass of: Nervous System Diseases [Disease/Finding]
subclass of: Signs and Symptoms [Disease/Finding]
type: NamedIndividual
Display_Name: Neurologic Manifestations
MeSH_CUI: M0014716
MeSH_DUI: D009461
MeSH_Definition: Clinical signs and symptoms caused by nervous system injury or dysfunction.
MeSH_Name: Neurologic Manifestations
NUI: N0000002173
RxNorm_CUI: 1025946
Synonym: Manifestations, Neurologic
Synonym: Manifestations, Neurological
Synonym: Neurologic Manifestation
Synonym: Neurologic Signs and Symptoms
Synonym: Neurological Manifestations
UMLS_CUI: C0027854
code: C4524
imported from: NDF-RT.owl

Neuromuscular Diseases [Disease/Finding]
type: Class
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Neuromuscular Diseases
MeSH_CUI: M0014726
MeSH_DUI: D009468
MeSH_Definition: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
MeSH_Name: Neuromuscular Diseases
NUI: N0000002176
RxNorm_CUI: 1026561
SNOMED_CID: 255522009
SNOMED_CID: 257277002
UMLS_CUI: C0027868
code: C4530
imported from: NDF-RT.owl

Nose Diseases [Disease/Finding]
type: Class
subclass of: Otorhinolaryngologic Diseases [Disease/Finding]
subclass of: Respiratory Tract Diseases [Disease/Finding]
Display_Name: Nose Diseases
MeSH_CUI: M0015012
MeSH_DUI: D009668
MeSH_Definition: Disorders of the nose, general or unspecified.
MeSH_Name: Nose Diseases
NUI: N0000002194
RxNorm_CUI: 1024498
SNOMED_CID: 89488007
Synonym: Nasal Diseases
Synonym: Nasal Disorders
UMLS_CUI: C0028432
code: C4566
imported from: NDF-RT.owl

Nutritional and Metabolic Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Nutritional and Metabolic Diseases
MeSH_CUI: M0015124
MeSH_DUI: D009750
MeSH_Definition: A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (ANABOLISM) or breakdown (CATABOLISM) of endogenous substances.
MeSH_Name: Nutritional and Metabolic Diseases
NUI: N0000002197
RxNorm_CUI: 1026553
UMLS_CUI: C0028715
code: C4572
imported from: NDF-RT.owl

Obsessive-Compulsive Disorder [Disease/Finding]
type: Class
subclass of: Anxiety Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Obsessive-Compulsive Disorder
MeSH_CUI: M0015170
MeSH_DUI: D009771
MeSH_Definition: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
MeSH_Name: Obsessive-Compulsive Disorder
NUI: N0000002203
RxNorm_CUI: 1022585
SNOMED_CID: 191736004
Synonym: Anankastic Personality
Synonym: Neurosis, Obsessive-Compulsive
UMLS_CUI: C0028768
code: C4584
imported from: NDF-RT.owl

Onchocerciasis [Disease/Finding]
type: Class
subclass of: Filariasis [Disease/Finding]
subclass of: Skin Diseases, Parasitic [Disease/Finding]
type: NamedIndividual
Display_Name: Onchocerciasis
MeSH_CUI: M0015295
MeSH_DUI: D009855
MeSH_Definition: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
MeSH_Name: Onchocerciasis
NUI: N0000002218
RxNorm_CUI: 984320
SNOMED_CID: 38539003
UMLS_CUI: C0029001
code: C4614
imported from: NDF-RT.owl

Otitis [Disease/Finding]
type: Class
subclass of: Ear Diseases [Disease/Finding]
Display_Name: Otitis
MeSH_CUI: M0015561
MeSH_DUI: D010031
MeSH_Definition: Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.
MeSH_Name: Otitis
NUI: N0000002264
RxNorm_CUI: 1022127
SNOMED_CID: 43275000
Synonym: Ear Inflammation
UMLS_CUI: C0029877
code: C4706
imported from: NDF-RT.owl

Otitis Media [Disease/Finding]
type: Class
subclass of: Otitis [Disease/Finding]
type: NamedIndividual
Display_Name: Otitis Media
MeSH_CUI: M0015563
MeSH_DUI: D010033
MeSH_Definition: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
MeSH_Name: Otitis Media
NUI: N0000002266
RxNorm_CUI: 1022862
SNOMED_CID: 65363002
Synonym: Middle Ear Inflammation
UMLS_CUI: C0029882
code: C4710
imported from: NDF-RT.owl

Otorhinolaryngologic Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Otorhinolaryngologic Diseases
MeSH_CUI: M0015572
MeSH_DUI: D010038
MeSH_Definition: Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases.
MeSH_Name: Otorhinolaryngologic Diseases
NUI: N0000002269
RxNorm_CUI: 985940
Synonym: ENT Diseases
Synonym: Otolaryngologic Diseases
Synonym: Otolaryngological Diseases
Synonym: Otorhinolaryngologic Disease
Synonym: Otorhinolaryngological Disease
UMLS_CUI: C0029896
code: C4716
imported from: NDF-RT.owl

Oxyuriasis [Disease/Finding]
type: Class
subclass of: Oxyurida Infections [Disease/Finding]
Display_Name: Oxyuriasis
MeSH_CUI: M0015707
MeSH_DUI: D010123
MeSH_Definition: Infection with nematodes of the superfamily OXYUROIDEA.
MeSH_Name: Oxyuriasis
NUI: N0000002275
RxNorm_CUI: 1024080
SNOMED_CID: 266162007
UMLS_CUI: C0030100
code: C4728
imported from: NDF-RT.owl

Pain [Disease/Finding]
type: Class
subclass of: Neurologic Manifestations [Disease/Finding]
type: NamedIndividual
Display_Name: Pain
MeSH_CUI: M0015742
MeSH_DUI: D010146
MeSH_Definition: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
MeSH_Name: Pain
NUI: N0000002278
RxNorm_CUI: 1021856
SNOMED_CID: 22253000
UMLS_CUI: C0030193
code: C4734
imported from: NDF-RT.owl

Pancreatic Diseases [Disease/Finding]
type: Class
subclass of: Digestive System Diseases [Disease/Finding]
Display_Name: Pancreatic Diseases
MeSH_CUI: M0015794
MeSH_DUI: D010182
MeSH_Definition: Pathological processes of the PANCREAS.
MeSH_Name: Pancreatic Diseases
NUI: N0000002285
RxNorm_CUI: 1022020
SNOMED_CID: 3855007
UMLS_CUI: C0030286
code: C4748
imported from: NDF-RT.owl

Pancreatic Neoplasms [Disease/Finding]
type: Class
subclass of: Digestive System Neoplasms [Disease/Finding]
subclass of: Endocrine Gland Neoplasms [Disease/Finding]
subclass of: Pancreatic Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Pancreatic Neoplasms
MeSH_CUI: M0015803
MeSH_DUI: D010190
MeSH_Definition: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
MeSH_Name: Pancreatic Neoplasms
NUI: N0000002288
RxNorm_CUI: 1026434
SNOMED_CID: 126859007
Synonym: Neoplasms, Pancreatic
Synonym: Pancreas Neoplasms
UMLS_CUI: C0030297
code: C4754
imported from: NDF-RT.owl

Paraproteinemias [Disease/Finding]
type: Class
subclass of: Blood Protein Disorders [Disease/Finding]
subclass of: Immunoproliferative Disorders [Disease/Finding]
Display_Name: Paraproteinemias
MeSH_CUI: M0015905
MeSH_DUI: D010265
MeSH_Definition: A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.
MeSH_Name: Paraproteinemias
NUI: N0000002317
RxNorm_CUI: 1022681
SNOMED_CID: 190816000
Synonym: Paraimmunoglobulinemias
UMLS_CUI: C0030489
code: C4812
imported from: NDF-RT.owl

Parasitic Diseases [Disease/Finding]
type: Class
subclass of: IDO_0000436
Display_Name: Parasitic Diseases
MeSH_CUI: M0015919
MeSH_DUI: D010272
MeSH_Definition: Infections or infestations with parasitic organisms. They are often contracted through contact with an intermediate vector, but may occur as the result of direct exposure.
MeSH_Name: Parasitic Diseases
NUI: N0000002319
RxNorm_CUI: 987316
SNOMED_CID: 17322007
UMLS_CUI: C0030499
code: C4816
imported from: NDF-RT.owl

Parasitic Diseases, Animal [Disease/Finding]
type: Class
subclass of: Parasitic Diseases [Disease/Finding]
Display_Name: Parasitic Diseases, Animal
MeSH_CUI: M0015920
MeSH_DUI: D010273
MeSH_Definition: Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.
MeSH_Name: Parasitic Diseases, Animal
NUI: N0000002320
RxNorm_CUI: 1027455
UMLS_CUI: C0030500
code: C4818
imported from: NDF-RT.owl

Parkinson Disease [Disease/Finding]
type: Class
subclass of: Neurodegenerative Diseases [Disease/Finding]
subclass of: Parkinsonian Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Parkinson Disease
MeSH_CUI: M0015963
MeSH_DUI: D010300
MeSH_Definition: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
MeSH_Name: Parkinson Disease
NUI: N0000002327
RxNorm_CUI: 1022466
SNOMED_CID: 49049000
Synonym: Idiopathic Parkinson Disease
Synonym: Idiopathic Parkinson's Disease
Synonym: Lewy Body Parkinson Disease
Synonym: Lewy Body Parkinson's Disease
Synonym: Paralysis Agitans
Synonym: Parkinson Disease, Idiopathic
Synonym: Parkinson's Disease
Synonym: Parkinson's Disease, Idiopathic
Synonym: Parkinson's Disease, Lewy Body
Synonym: Primary Parkinsonism
UMLS_CUI: C0030567
code: C4832
imported from: NDF-RT.owl

Pathologic Processes [Disease/Finding]
type: Class
subclass of: Pathological Conditions, Signs and Symptoms [Disease/Finding]
type: NamedIndividual
Display_Name: Pathologic Processes
MeSH_CUI: M0016012
MeSH_DUI: D010335
MeSH_Definition: The abnormal mechanisms and forms involved in the dysfunctions of tissues and organs.
MeSH_Name: Pathologic Processes
NUI: N0000002338
RxNorm_CUI: 1025320
SNOMED_CID: 308489006
SNOMED_CID: 370135005
Synonym: Pathological Processes
Synonym: Processes, Pathologic
UMLS_CUI: C0030660
code: C4854
imported from: NDF-RT.owl

Pemphigus [Disease/Finding]
type: Class
subclass of: Autoimmune Diseases [Disease/Finding]
subclass of: Skin Diseases, Vesiculobullous [Disease/Finding]
type: NamedIndividual
Display_Name: Pemphigus
MeSH_CUI: M0016112
MeSH_DUI: D010392
MeSH_Definition: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
MeSH_Name: Pemphigus
NUI: N0000002347
RxNorm_CUI: 1025707
SNOMED_CID: 65172003
UMLS_CUI: C0030807
code: C4872
imported from: NDF-RT.owl

Peptic Ulcer [Disease/Finding]
type: Class
subclass of: Duodenal Diseases [Disease/Finding]
subclass of: Stomach Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Peptic Ulcer
MeSH_CUI: M0016211
MeSH_DUI: D010437
MeSH_Definition: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
MeSH_Name: Peptic Ulcer
NUI: N0000002351
RxNorm_CUI: 1024813
SNOMED_CID: 13200003
SNOMED_CID: 196697002
SNOMED_CID: 266437002
Synonym: Gastroduodenal Ulcer
UMLS_CUI: C0030920
code: C4880
imported from: NDF-RT.owl

Pericarditis [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Pericarditis
MeSH_CUI: M0016303
MeSH_DUI: D010493
MeSH_Definition: Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.
MeSH_Name: Pericarditis
NUI: N0000002362
RxNorm_CUI: 1025582
SNOMED_CID: 3238004
UMLS_CUI: C0031046
code: C4902
imported from: NDF-RT.owl

Pericarditis, Constrictive [Disease/Finding]
type: Class
subclass of: Pericarditis [Disease/Finding]
type: NamedIndividual
Display_Name: Pericarditis, Constrictive
MeSH_CUI: M0016304
MeSH_DUI: D010494
MeSH_Definition: Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
MeSH_Name: Pericarditis, Constrictive
NUI: N0000002363
RxNorm_CUI: 1026769
SNOMED_CID: 85598007
Synonym: Constrictive Pericarditis
UMLS_CUI: C0031048
code: C4904
imported from: NDF-RT.owl

Pharyngeal Diseases [Disease/Finding]
type: Class
subclass of: Stomatognathic Diseases [Disease/Finding]
subclass of: Otorhinolaryngologic Diseases [Disease/Finding]
Display_Name: Pharyngeal Diseases
MeSH_CUI: M0016479
MeSH_DUI: D010608
MeSH_Definition: Pathological processes involving the PHARYNX.
MeSH_Name: Pharyngeal Diseases
NUI: N0000002385
RxNorm_CUI: 1024885
SNOMED_CID: 195832000
SNOMED_CID: 75860007
Synonym: Diseases of Pharynx
Synonym: Pharynx Diseases
UMLS_CUI: C0031345
code: C4948
imported from: NDF-RT.owl

Pharyngitis [Disease/Finding]
type: Class
subclass of: Pharyngeal Diseases [Disease/Finding]
subclass of: Respiratory Tract Infections [Disease/Finding]
Display_Name: Pharyngitis
MeSH_CUI: M0016483
MeSH_DUI: D010612
MeSH_Definition: Inflammation of the throat (PHARYNX).
MeSH_Name: Pharyngitis
NUI: N0000002387
RxNorm_CUI: 1024296
SNOMED_CID: 405737000
UMLS_CUI: C0031350
code: C4952
imported from: NDF-RT.owl

Phenylketonurias [Disease/Finding]
type: Class
subclass of: Amino Acid Metabolism, Inborn Errors [Disease/Finding]
subclass of: Brain Diseases, Metabolic, Inborn [Disease/Finding]
Display_Name: Phenylketonurias
MeSH_CUI: M0016567
MeSH_DUI: D010661
MeSH_Definition: A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).
MeSH_Name: Phenylketonurias
NUI: N0000002389
RxNorm_CUI: 1023735
Synonym: Phenylketonuria
UMLS_CUI: C0031485
code: C4956
imported from: NDF-RT.owl

Phlebitis [Disease/Finding]
type: Class
subclass of: Vasculitis [Disease/Finding]
subclass of: Peripheral Vascular Diseases [Disease/Finding]
Display_Name: Phlebitis
MeSH_CUI: M0016608
MeSH_DUI: D010689
MeSH_Definition: Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).
MeSH_Name: Phlebitis
NUI: N0000002393
RxNorm_CUI: 986358
SNOMED_CID: 61599003
UMLS_CUI: C0031542
code: C4964
imported from: NDF-RT.owl

Photosensitivity Disorders [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Photosensitivity Disorders
MeSH_CUI: M0016756
MeSH_DUI: D010787
MeSH_Definition: Abnormal responses to sunlight or artificial light due to extreme reactivity of light-absorbing molecules in tissues. It refers almost exclusively to skin photosensitivity, including sunburn, reactions due to repeated prolonged exposure in the absence of photosensitizing factors, and reactions requiring photosensitizing factors such as photosensitizing agents and certain diseases. With restricted reference to skin tissue, it does not include photosensitivity of the eye to light, as in photophobia or photosensitive epilepsy.
MeSH_Name: Photosensitivity Disorders
NUI: N0000002396
RxNorm_CUI: 1026591
SNOMED_CID: 22649008
Synonym: Photodermatitis
UMLS_CUI: C0031762
code: C4970
imported from: NDF-RT.owl

Pneumonia [Disease/Finding]
type: Class
subclass of: Lung Diseases [Disease/Finding]
subclass of: Respiratory Tract Infections [Disease/Finding]
Display_Name: Pneumonia
MeSH_CUI: M0017064
MeSH_DUI: D011014
MeSH_Definition: Inflammation of any part, segment or lobe, of the lung parenchyma.
MeSH_Name: Pneumonia
NUI: N0000002432
RxNorm_CUI: 1022757
SNOMED_CID: 205237003
SNOMED_CID: 233604007
Synonym: Lung Inflammation
Synonym: Pneumonitis
Synonym: Pulmonary Inflammation
UMLS_CUI: C0032285
code: C5042
imported from: NDF-RT.owl

Pneumonia, Mycoplasma [Disease/Finding]
type: Class
subclass of: Mycoplasma Infections [Disease/Finding]
subclass of: Pneumonia, Bacterial [Disease/Finding]
type: NamedIndividual
Display_Name: Pneumonia, Mycoplasma
MeSH_CUI: M0017072
MeSH_DUI: D011019
MeSH_Definition: Interstitial pneumonia caused by extensive infection of the lungs (LUNG) and BRONCHI, particularly the lower lobes of the lungs, by MYCOPLASMA PNEUMONIAE in humans. In SHEEP, it is caused by MYCOPLASMA OVIPNEUMONIAE. In CATTLE, it may be caused by MYCOPLASMA DISPAR.
MeSH_Name: Pneumonia, Mycoplasma
NUI: N0000002436
RxNorm_CUI: 1023268
SNOMED_CID: 46970008
Synonym: Mycoplasma Pneumonia
Synonym: Pneumonia, Primary Atypical
UMLS_CUI: C0032302
code: C5050
imported from: NDF-RT.owl

Poisoning [Disease/Finding]
type: Class
subclass of: Substance-Related Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Poisoning
MeSH_CUI: M0017099
MeSH_DUI: D011041
MeSH_Definition: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.
MeSH_Name: Poisoning
NUI: N0000002447
RxNorm_CUI: 1026915
SNOMED_CID: 75478009
UMLS_CUI: C0032343
code: C5072
imported from: NDF-RT.owl

Porphyrias [Disease/Finding]
type: Class
subclass of: Metabolism, Inborn Errors [Disease/Finding]
subclass of: Skin Diseases, Metabolic [Disease/Finding]
Display_Name: Porphyrias
MeSH_CUI: M0017334
MeSH_DUI: D011164
MeSH_Definition: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
MeSH_Name: Porphyrias
NUI: N0000002464
RxNorm_CUI: 1022410
SNOMED_CID: 29094004
SNOMED_CID: 371628009
SNOMED_CID: 418470004
Synonym: Porphyria
UMLS_CUI: C0032708
code: C5106
imported from: NDF-RT.owl

Postoperative Complications [Disease/Finding]
type: Class
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Postoperative Complications
MeSH_CUI: M0017367
MeSH_DUI: D011183
MeSH_Definition: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
MeSH_Name: Postoperative Complications
NUI: N0000002467
RxNorm_CUI: 1022600
SNOMED_CID: 385486001
Synonym: Complication, Postoperative
UMLS_CUI: C0032787
code: C5112
imported from: NDF-RT.owl

Pre-Excitation Syndromes [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
Display_Name: Pre-Excitation Syndromes
MeSH_CUI: M0017444
MeSH_DUI: D011226
MeSH_Definition: A group of conditions in which HEART VENTRICLE activation by the atrial impulse is faster than the normal impulse conduction from the SINOATRIAL NODE. In these pre-excitation syndromes, atrial impulses often bypass the ATRIOVENTRICULAR NODE delay and travel via ACCESSORY CONDUCTING PATHWAYS connecting the atrium directly to the BUNDLE OF HIS.
MeSH_Name: Pre-Excitation Syndromes
NUI: N0000002474
RxNorm_CUI: 1026072
Synonym: Preexcitation Syndrome
UMLS_CUI: C0032915
code: C5126
imported from: NDF-RT.owl

Pregnancy Complications [Disease/Finding]
type: Class
subclass of: Female Urogenital Diseases and Pregnancy Complications [Disease/Finding]
type: NamedIndividual
Display_Name: Pregnancy Complications
MeSH_CUI: M0017474
MeSH_DUI: D011248
MeSH_Definition: Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
MeSH_Name: Pregnancy Complications
NUI: N0000002478
RxNorm_CUI: 1023402
SNOMED_CID: 198881004
SNOMED_CID: 90821003
Synonym: Complications, Pregnancy
UMLS_CUI: C0032962
code: C5134
imported from: NDF-RT.owl

Protozoan Infections [Disease/Finding]
type: Class
subclass of: Parasitic Diseases [Disease/Finding]
Display_Name: Protozoan Infections
MeSH_CUI: M0017926
MeSH_DUI: D011528
MeSH_Definition: Infections with unicellular organisms formerly members of the subkingdom Protozoa.
MeSH_Name: Protozoan Infections
NUI: N0000002508
RxNorm_CUI: 1021795
SNOMED_CID: 95896000
Synonym: Infections, Protozoan
UMLS_CUI: C0033740
code: C5194
imported from: NDF-RT.owl

Protozoan Infections, Animal [Disease/Finding]
type: Class
subclass of: Parasitic Diseases, Animal [Disease/Finding]
subclass of: Protozoan Infections [Disease/Finding]
Display_Name: Protozoan Infections, Animal
MeSH_CUI: M0017927
MeSH_DUI: D011529
MeSH_Definition: Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
MeSH_Name: Protozoan Infections, Animal
NUI: N0000002509
RxNorm_CUI: 1031669
UMLS_CUI: C0033741
code: C5196
imported from: NDF-RT.owl

Psoriasis [Disease/Finding]
type: Class
subclass of: Skin Diseases, Papulosquamous [Disease/Finding]
type: NamedIndividual
Display_Name: Psoriasis
MeSH_CUI: M0017975
MeSH_DUI: D011565
MeSH_Definition: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
MeSH_Name: Psoriasis
NUI: N0000002526
RxNorm_CUI: 1022582
SNOMED_CID: 200961000
SNOMED_CID: 9014002
UMLS_CUI: C0033860
code: C5230
imported from: NDF-RT.owl

Psychotic Disorders [Disease/Finding]
type: Class
subclass of: Schizophrenia and Disorders with Psychotic Features [Disease/Finding]
type: NamedIndividual
Display_Name: Psychotic Disorders
MeSH_CUI: M0018060
MeSH_DUI: D011618
MeSH_Definition: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
MeSH_Name: Psychotic Disorders
NUI: N0000002532
RxNorm_CUI: 1023496
SNOMED_CID: 69322001
Synonym: Psychoses
UMLS_CUI: C0033975
code: C5242
imported from: NDF-RT.owl

Puberty, Precocious [Disease/Finding]
type: Class
subclass of: Gonadal Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Puberty, Precocious
MeSH_CUI: M0018083
MeSH_DUI: D011629
MeSH_Definition: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
MeSH_Name: Puberty, Precocious
NUI: N0000002535
RxNorm_CUI: 1023098
SNOMED_CID: 123527003
SNOMED_CID: 400179000
Synonym: Precocious Puberty
UMLS_CUI: C0034013
code: C5248
imported from: NDF-RT.owl

Rectal Diseases [Disease/Finding]
type: Class
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Rectal Diseases
MeSH_CUI: M0018654
MeSH_DUI: D012002
MeSH_Definition: Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).
MeSH_Name: Rectal Diseases
NUI: N0000002578
RxNorm_CUI: 1024401
SNOMED_CID: 5964004
UMLS_CUI: C0034882
code: C5334
imported from: NDF-RT.owl

Respiration Disorders [Disease/Finding]
type: Class
subclass of: Respiratory Tract Diseases [Disease/Finding]
Display_Name: Respiration Disorders
MeSH_CUI: M0018879
MeSH_DUI: D012120
MeSH_Definition: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
MeSH_Name: Respiration Disorders
NUI: N0000002595
RxNorm_CUI: 1022107
SNOMED_CID: 50043002
UMLS_CUI: C0035204
code: C5368
imported from: NDF-RT.owl

Respiratory Distress Syndrome, Adult [Disease/Finding]
type: Class
subclass of: Lung Diseases [Disease/Finding]
subclass of: Respiration Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Respiratory Distress Syndrome, Adult
MeSH_CUI: M0018891
MeSH_DUI: D012128
MeSH_Definition: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
MeSH_Name: Respiratory Distress Syndrome, Adult
NUI: N0000002597
RxNorm_CUI: 990085
SNOMED_CID: 67782005
SNOMED_CID: 95437004
Synonym: ARDS, Human
Synonym: Acute Respiratory Distress Syndrome
Synonym: Adult Respiratory Distress Syndrome
Synonym: Respiratory Distress Syndrome, Acute
Synonym: Shock Lung
UMLS_CUI: C0035222
code: C5372
imported from: NDF-RT.owl

Respiratory Hypersensitivity [Disease/Finding]
type: Class
subclass of: Hypersensitivity, Immediate [Disease/Finding]
subclass of: Respiratory Tract Diseases [Disease/Finding]
Display_Name: Respiratory Hypersensitivity
MeSH_CUI: M0018896
MeSH_DUI: D012130
MeSH_Definition: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.
MeSH_Name: Respiratory Hypersensitivity
NUI: N0000002598
RxNorm_CUI: 1025923
Synonym: Hypersensitivity, Respiratory
UMLS_CUI: C0035228
code: C5374
imported from: NDF-RT.owl

Respiratory Tract Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Respiratory Tract Diseases
MeSH_CUI: M0018918
MeSH_DUI: D012140
MeSH_Name: Respiratory Tract Diseases
NUI: N0000002602
RxNorm_CUI: 1024163
UMLS_CUI: C0035242
code: C5382
imported from: NDF-RT.owl

Respiratory Tract Infections [Disease/Finding]
type: Class
subclass of: Infection [Disease/Finding]
subclass of: Respiratory Tract Diseases [Disease/Finding]
Display_Name: Respiratory Tract Infections
MeSH_CUI: M0018919
MeSH_DUI: D012141
MeSH_Definition: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
MeSH_Name: Respiratory Tract Infections
NUI: N0000002603
RxNorm_CUI: 1025855
SNOMED_CID: 275498002
Synonym: Infections, Respiratory
Synonym: Infections, Respiratory Tract
Synonym: Respiratory Infections
UMLS_CUI: C0035243
code: C5384
imported from: NDF-RT.owl

Retinal Degeneration [Disease/Finding]
type: Class
subclass of: Retinal Diseases [Disease/Finding]
Display_Name: Retinal Degeneration
MeSH_CUI: M0018942
MeSH_DUI: D012162
MeSH_Definition: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
MeSH_Name: Retinal Degeneration
NUI: N0000002607
RxNorm_CUI: 1026317
SNOMED_CID: 95695004
UMLS_CUI: C0035304
code: C5392
imported from: NDF-RT.owl

Retinal Diseases [Disease/Finding]
type: Class
subclass of: Eye Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Retinal Diseases
MeSH_CUI: M0018945
MeSH_DUI: D012164
MeSH_Name: Retinal Diseases
NUI: N0000002609
RxNorm_CUI: 1023467
SNOMED_CID: 29555009
SNOMED_CID: 399625000
UMLS_CUI: C0035309
code: C5396
imported from: NDF-RT.owl

Retroviridae Infections [Disease/Finding]
type: Class
subclass of: RNA Virus Infections [Disease/Finding]
Display_Name: Retroviridae Infections
MeSH_CUI: M0018986
MeSH_DUI: D012192
MeSH_Definition: Virus diseases caused by the RETROVIRIDAE.
MeSH_Name: Retroviridae Infections
NUI: N0000002623
RxNorm_CUI: 1025440
SNOMED_CID: 105635000
Synonym: Infections, Retroviridae
Synonym: Infections, Retrovirus
Synonym: Retrovirus Infections
UMLS_CUI: C0035369
code: C5424
imported from: NDF-RT.owl

Reye Syndrome [Disease/Finding]
type: Class
subclass of: Brain Diseases, Metabolic [Disease/Finding]
subclass of: Fatty Liver [Disease/Finding]
type: NamedIndividual
Display_Name: Reye Syndrome
MeSH_CUI: M0018992
MeSH_DUI: D012202
MeSH_Definition: A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism.
MeSH_Name: Reye Syndrome
NUI: N0000002624
RxNorm_CUI: 1026604
SNOMED_CID: 74351001
Synonym: Fatty Liver with Encephalopathy
Synonym: Reye's Syndrome
Synonym: Reye-Johnson Syndrome
UMLS_CUI: C0035400
code: C5426
imported from: NDF-RT.owl

Rheumatic Diseases [Disease/Finding]
type: Class
subclass of: Connective Tissue Diseases [Disease/Finding]
subclass of: Musculoskeletal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Rheumatic Diseases
MeSH_CUI: M0019014
MeSH_DUI: D012216
MeSH_Definition: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
MeSH_Name: Rheumatic Diseases
NUI: N0000002632
RxNorm_CUI: 1022758
SNOMED_CID: 203100003
SNOMED_CID: 396332003
Synonym: Rheumatism
UMLS_CUI: C0035435
code: C5442
imported from: NDF-RT.owl

Rhinitis [Disease/Finding]
type: Class
subclass of: Nose Diseases [Disease/Finding]
subclass of: Respiratory Tract Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Rhinitis
MeSH_CUI: M0019019
MeSH_DUI: D012220
MeSH_Definition: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
MeSH_Name: Rhinitis
NUI: N0000002634
RxNorm_CUI: 1023076
SNOMED_CID: 70076002
Synonym: Nasal Catarrh
UMLS_CUI: C0035455
code: C5446
imported from: NDF-RT.owl

Rhinitis, Allergic, Perennial [Disease/Finding]
type: Class
subclass of: Respiratory Hypersensitivity [Disease/Finding]
subclass of: Rhinitis [Disease/Finding]
type: NamedIndividual
Display_Name: Rhinitis, Allergic, Perennial
MeSH_CUI: M0019020
MeSH_DUI: D012221
MeSH_Definition: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
MeSH_Name: Rhinitis, Allergic, Perennial
NUI: N0000002635
RxNorm_CUI: 1025485
SNOMED_CID: 38103000
Synonym: Rhinitis, Allergic, Nonseasonal
UMLS_CUI: C0035457
code: C5448
imported from: NDF-RT.owl

RNA Virus Infections [Disease/Finding]
type: Class
subclass of: DOID 934
Display_Name: RNA Virus Infections
MeSH_CUI: M0019160
MeSH_DUI: D012327
MeSH_Name: RNA Virus Infections
NUI: N0000002650
RxNorm_CUI: 1027571
Synonym: Infections, RNA Virus
UMLS_CUI: C0035690
code: C5478
imported from: NDF-RT.owl

Salmonella Infections [Disease/Finding]
type: Class
subclass of: Enterobacteriaceae Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Salmonella Infections
MeSH_CUI: M0019393
MeSH_DUI: D012480
MeSH_Definition: Infections with bacteria of the genus SALMONELLA.
MeSH_Name: Salmonella Infections
NUI: N0000002666
RxNorm_CUI: 1025316
SNOMED_CID: 302231008
SNOMED_CID: 90974009
Synonym: Infections, Salmonella
Synonym: Salmonellosis
UMLS_CUI: C0036117
code: C5510
imported from: NDF-RT.owl

Sarcoma [Disease/Finding]
type: Class
subclass of: Neoplasms, Connective and Soft Tissue [Disease/Finding]
Display_Name: Sarcoma
MeSH_CUI: M0019428
MeSH_DUI: D012509
MeSH_Definition: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
MeSH_Name: Sarcoma
NUI: N0000002671
RxNorm_CUI: 1021824
SNOMED_CID: 269469005
Synonym: Sarcoma, Soft Tissue
UMLS_CUI: C1261473
code: C5520
imported from: NDF-RT.owl

Sarcoma, Kaposi [Disease/Finding]
type: Class
subclass of: Herpesviridae Infections [Disease/Finding]
subclass of: Neoplasms, Vascular Tissue [Disease/Finding]
subclass of: Sarcoma [Disease/Finding]
type: NamedIndividual
Display_Name: Sarcoma, Kaposi
MeSH_CUI: M0019437
MeSH_DUI: D012514
MeSH_Definition: A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
MeSH_Name: Sarcoma, Kaposi
NUI: N0000002676
RxNorm_CUI: 1027423
SNOMED_CID: 109385007
Synonym: Kaposi Sarcoma
Synonym: Kaposi's Sarcoma
UMLS_CUI: C0036220
code: C5530
imported from: NDF-RT.owl

Scabies [Disease/Finding]
type: Class
subclass of: Mite Infestations [Disease/Finding]
type: NamedIndividual
Display_Name: Scabies
MeSH_CUI: M0019458
MeSH_DUI: D012532
MeSH_Definition: A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
MeSH_Name: Scabies
NUI: N0000002681
RxNorm_CUI: 1022265
SNOMED_CID: 128869009
UMLS_CUI: C0036262
code: C5540
imported from: NDF-RT.owl

Schizophrenia [Disease/Finding]
type: Class
subclass of: Schizophrenia and Disorders with Psychotic Features [Disease/Finding]
type: NamedIndividual
Display_Name: Schizophrenia
MeSH_CUI: M0019489
MeSH_DUI: D012559
MeSH_Definition: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
MeSH_Name: Schizophrenia
NUI: N0000002690
RxNorm_CUI: 1022169
SNOMED_CID: 191526005
SNOMED_CID: 191528006
SNOMED_CID: 58214004
Synonym: Dementia Praecox
Synonym: Schizophrenic Disorders
UMLS_CUI: C0036341
code: C5558
imported from: NDF-RT.owl

Scleroderma, Systemic [Disease/Finding]
type: Class
subclass of: Connective Tissue Diseases [Disease/Finding]
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Scleroderma, Systemic
MeSH_CUI: M0019543
MeSH_DUI: D012595
MeSH_Definition: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
MeSH_Name: Scleroderma, Systemic
NUI: N0000002701
RxNorm_CUI: 1022426
SNOMED_CID: 89155008
Synonym: Sclerosis, Systemic
Synonym: Systemic Scleroderma
Synonym: Systemic Sclerosis
UMLS_CUI: C0036421
code: C5580
imported from: NDF-RT.owl

Sebaceous Gland Diseases [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Sebaceous Gland Diseases
MeSH_CUI: M0019581
MeSH_DUI: D012625
MeSH_Definition: Diseases of the sebaceous glands such as sebaceous hyperplasia and sebaceous cell carcinoma (SEBACEOUS GLAND NEOPLASMS).
MeSH_Name: Sebaceous Gland Diseases
NUI: N0000002710
RxNorm_CUI: 1021910
SNOMED_CID: 3441005
UMLS_CUI: C0036502
code: C5598
imported from: NDF-RT.owl

Sensation Disorders [Disease/Finding]
type: Class
subclass of: Neurologic Manifestations [Disease/Finding]
Display_Name: Sensation Disorders
MeSH_CUI: M0019651
MeSH_DUI: D012678
MeSH_Definition: Disorders of the special senses (i.e., VISION; HEARING; TASTE; and SMELL) or somatosensory system (i.e., afferent components of the PERIPHERAL NERVOUS SYSTEM).
MeSH_Name: Sensation Disorders
NUI: N0000002715
RxNorm_CUI: 1030029
UMLS_CUI: C0036659
code: C5608
imported from: NDF-RT.owl

Sexually Transmitted Diseases [Disease/Finding]
type: Class
subclass of: Genital Diseases, Female [Disease/Finding]
subclass of: Genital Diseases, Male [Disease/Finding]
subclass of: Infection [Disease/Finding]
subclass of: DOID 934
Display_Name: Sexually Transmitted Diseases
MeSH_CUI: M0019758
MeSH_DUI: D012749
MeSH_Definition: Diseases due to or propagated by sexual contact.
MeSH_Name: Sexually Transmitted Diseases
NUI: N0000002724
RxNorm_CUI: 1023328
SNOMED_CID: 8098009
Synonym: STDs
Synonym: Venereal Diseases
UMLS_CUI: C0036916
code: C5626
imported from: NDF-RT.owl

Sezary Syndrome [Disease/Finding]
type: Class
subclass of: Lymphoma, T-Cell, Cutaneous [Disease/Finding]
type: NamedIndividual
Display_Name: Sezary Syndrome
MeSH_CUI: M0019760
MeSH_DUI: D012751
MeSH_Definition: A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells).
MeSH_Name: Sezary Syndrome
NUI: N0000002725
RxNorm_CUI: 1022616
SNOMED_CID: 118611004
SNOMED_CID: 188629004
Synonym: Erythroderma, Sezary
Synonym: Sezary's Lymphoma
UMLS_CUI: C0036920
code: C5628
imported from: NDF-RT.owl

Shock [Disease/Finding]
type: Class
subclass of: Pathologic Processes [Disease/Finding]
type: NamedIndividual
Display_Name: Shock
MeSH_CUI: M0019782
MeSH_DUI: D012769
MeSH_Definition: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
MeSH_Name: Shock
NUI: N0000002728
RxNorm_CUI: 1023333
SNOMED_CID: 274729009
SNOMED_CID: 27942005
Synonym: Circulatory Collapse
Synonym: Circulatory Failure
UMLS_CUI: C0036974
code: C5634
imported from: NDF-RT.owl

Shock, Cardiogenic [Disease/Finding]
type: Class
subclass of: Myocardial Infarction [Disease/Finding]
subclass of: Shock [Disease/Finding]
type: NamedIndividual
Display_Name: Shock, Cardiogenic
MeSH_CUI: M0019783
MeSH_DUI: D012770
MeSH_Definition: Shock resulting from diminution of cardiac output in heart disease.
MeSH_Name: Shock, Cardiogenic
NUI: N0000002729
RxNorm_CUI: 1026337
SNOMED_CID: 89138009
UMLS_CUI: C0036980
code: C5636
imported from: NDF-RT.owl

Signs and Symptoms [Disease/Finding]
type: Class
subclass of: Pathological Conditions, Signs and Symptoms [Disease/Finding]
Display_Name: Signs and Symptoms
MeSH_CUI: M0019845
MeSH_DUI: D012816
MeSH_Definition: Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient.
MeSH_Name: Signs and Symptoms
NUI: N0000002748
RxNorm_CUI: 1024593
UMLS_CUI: C0037088
code: C5674
imported from: NDF-RT.owl

Signs and Symptoms, Digestive [Disease/Finding]
type: Class
subclass of: Signs and Symptoms [Disease/Finding]
Display_Name: Signs and Symptoms, Digestive
MeSH_CUI: M0019846
MeSH_DUI: D012817
MeSH_Definition: Digestive system manifestations of diseases of the gastrointestinal system or of other organs.
MeSH_Name: Signs and Symptoms, Digestive
NUI: N0000002749
RxNorm_CUI: 1029901
UMLS_CUI: C0037089
code: C5676
imported from: NDF-RT.owl

Skin Diseases [Disease/Finding]
type: Class
subclass of: Skin and Connective Tissue Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Skin Diseases
MeSH_CUI: M0019929
MeSH_DUI: D012871
MeSH_Name: Skin Diseases
NUI: N0000002761
RxNorm_CUI: 1022858
SNOMED_CID: 95320005
Synonym: Dermatoses
Synonym: Dermatosis
UMLS_CUI: C0037274
code: C5700
imported from: NDF-RT.owl

Skin Diseases, Vesiculobullous [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Skin Diseases, Vesiculobullous
MeSH_CUI: M0019930
MeSH_DUI: D012872
MeSH_Definition: Skin diseases characterized by local or general distributions of blisters. They are classified according to the site and mode of blister formation. Lesions can appear spontaneously or be precipitated by infection, trauma, or sunlight. Etiologies include immunologic and genetic factors. (From Scientific American Medicine, 1990)
MeSH_Name: Skin Diseases, Vesiculobullous
NUI: N0000002762
RxNorm_CUI: 1027633
Synonym: Vesiculobullous Dermatoses
Synonym: Vesiculobullous Skin Diseases
UMLS_CUI: C0037275
code: C5702
imported from: NDF-RT.owl

Skin Diseases, Genetic [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
subclass of: Genetic Diseases, Inborn [Disease/Finding]
Display_Name: Skin Diseases, Genetic
MeSH_CUI: M0019934
MeSH_DUI: D012873
MeSH_Definition: Diseases of the skin with a genetic component, usually the result of various inborn errors of metabolism.
MeSH_Name: Skin Diseases, Genetic
NUI: N0000002763
RxNorm_CUI: 986094
SNOMED_CID: 239001006
Synonym: Genetic Skin Diseases
UMLS_CUI: C0037277
code: C5704
imported from: NDF-RT.owl

Skin Diseases, Infectious [Disease/Finding]
type: Class
subclass of: Infection [Disease/Finding]
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Skin Diseases, Infectious
MeSH_CUI: M0019935
MeSH_DUI: D012874
MeSH_Definition: Skin diseases caused by bacteria, fungi, parasites, or viruses.
MeSH_Name: Skin Diseases, Infectious
NUI: N0000002764
RxNorm_CUI: 1025346
SNOMED_CID: 108365000
Synonym: Infectious Skin Diseases
UMLS_CUI: C0037278
code: C5706
imported from: NDF-RT.owl

Skin Diseases, Metabolic [Disease/Finding]
type: Class
subclass of: Metabolic Diseases [Disease/Finding]
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Skin Diseases, Metabolic
MeSH_CUI: M0019936
MeSH_DUI: D012875
MeSH_Definition: Diseases of the skin associated with underlying metabolic disorders.
MeSH_Name: Skin Diseases, Metabolic
NUI: N0000002765
RxNorm_CUI: 1027237
Synonym: Metabolic Skin Diseases
UMLS_CUI: C0037279
code: C5708
imported from: NDF-RT.owl

Skin Diseases, Parasitic [Disease/Finding]
type: Class
subclass of: Parasitic Diseases [Disease/Finding]
subclass of: Skin Diseases, Infectious [Disease/Finding]
Display_Name: Skin Diseases, Parasitic
MeSH_CUI: M0019937
MeSH_DUI: D012876
MeSH_Definition: Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.
MeSH_Name: Skin Diseases, Parasitic
NUI: N0000002766
RxNorm_CUI: 1023415
SNOMED_CID: 128938009
SNOMED_CID: 33042004
Synonym: Parasitic Skin Diseases
UMLS_CUI: C0037280
code: C5710
imported from: NDF-RT.owl

Skin Neoplasms [Disease/Finding]
type: Class
subclass of: Neoplasms by Site [Disease/Finding]
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Skin Neoplasms
MeSH_CUI: M0019939
MeSH_DUI: D012878
MeSH_Definition: Tumors or cancer of the SKIN.
MeSH_Name: Skin Neoplasms
NUI: N0000002768
RxNorm_CUI: 1025991
SNOMED_CID: 126488004
Synonym: Neoplasms, Skin
UMLS_CUI: C0037286
code: C5714
imported from: NDF-RT.owl

Skin Ulcer [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Skin Ulcer
MeSH_CUI: M0019944
MeSH_DUI: D012883
MeSH_Name: Skin Ulcer
NUI: N0000002769
RxNorm_CUI: 1023651
SNOMED_CID: 247454005
SNOMED_CID: 46742003
UMLS_CUI: C0037299
code: C5716
imported from: NDF-RT.owl

Slow Virus Diseases [Disease/Finding]
type: Class
subclass of: DOID 934
Display_Name: Slow Virus Diseases
MeSH_CUI: M0019974
MeSH_DUI: D012897
MeSH_Definition: Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.
MeSH_Name: Slow Virus Diseases
NUI: N0000002775
RxNorm_CUI: 1030191
UMLS_CUI: C0037341
code: C5728
imported from: NDF-RT.owl

Staphylococcal Infections [Disease/Finding]
type: Class
subclass of: Gram-Positive Bacterial Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Staphylococcal Infections
MeSH_CUI: M0020423
MeSH_DUI: D013203
MeSH_Definition: Infections with bacteria of the genus STAPHYLOCOCCUS.
MeSH_Name: Staphylococcal Infections
NUI: N0000002817
RxNorm_CUI: 1023915
SNOMED_CID: 56038003
Synonym: Infections, Staphylococcal
UMLS_CUI: C0038160
code: C5812
imported from: NDF-RT.owl

Staphylococcal Skin Infections [Disease/Finding]
type: Class
subclass of: Staphylococcal Infections [Disease/Finding]
subclass of: Skin Diseases, Bacterial [Disease/Finding]
type: NamedIndividual
Display_Name: Staphylococcal Skin Infections
MeSH_CUI: M0020427
MeSH_DUI: D013207
MeSH_Definition: Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.
MeSH_Name: Staphylococcal Skin Infections
NUI: N0000002819
RxNorm_CUI: 1022363
SNOMED_CID: 371308001
SNOMED_CID: 402938009
Synonym: Infections, Staphylococcal Skin
Synonym: Skin Diseases, Staphylococcal
Synonym: Skin Infections, Staphylococcal
Synonym: Staphylococcal Diseases, Skin
Synonym: Staphylococcal Infections, Skin
Synonym: Staphylococcal Skin Diseases
UMLS_CUI: C0038166
code: C5816
imported from: NDF-RT.owl

Stomach Diseases [Disease/Finding]
type: Class
subclass of: Gastrointestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Stomach Diseases
MeSH_CUI: M0020542
MeSH_DUI: D013272
MeSH_Definition: Pathological processes involving the STOMACH.
MeSH_Name: Stomach Diseases
NUI: N0000002826
RxNorm_CUI: 988579
SNOMED_CID: 29384001
Synonym: Gastric Diseases
UMLS_CUI: C0038354
code: C5830
imported from: NDF-RT.owl

Streptococcal Infections [Disease/Finding]
type: Class
subclass of: Gram-Positive Bacterial Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Streptococcal Infections
MeSH_CUI: M0020568
MeSH_DUI: D013290
MeSH_Definition: Infections with bacteria of the genus STREPTOCOCCUS.
MeSH_Name: Streptococcal Infections
NUI: N0000002837
RxNorm_CUI: 1022383
SNOMED_CID: 85769006
Synonym: Infections, Streptococcal
UMLS_CUI: C0038395
code: C5852
imported from: NDF-RT.owl

Strongyloidiasis [Disease/Finding]
type: Class
subclass of: Rhabditida Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Strongyloidiasis
MeSH_CUI: M0020615
MeSH_DUI: D013322
MeSH_Definition: Infection with nematodes of the genus STRONGYLOIDES. The presence of larvae may produce pneumonitis and the presence of adult worms in the intestine could lead to moderate to severe diarrhea.
MeSH_Name: Strongyloidiasis
NUI: N0000002841
RxNorm_CUI: 1024903
SNOMED_CID: 1214006
UMLS_CUI: C0038463
code: C5860
imported from: NDF-RT.owl

Pathological Conditions, Signs and Symptoms [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Pathological Conditions, Signs and Symptoms
MeSH_CUI: M0020949
MeSH_DUI: D013568
MeSH_Definition: Abnormal anatomical or physiological conditions and objective or subjective manifestations of disease, not classified as disease or syndrome.
MeSH_Name: Pathological Conditions, Signs and Symptoms
NUI: N0000002872
RxNorm_CUI: 984268
Synonym: Symptoms and General Pathology
UMLS_CUI: C0039058
code: C5922
imported from: NDF-RT.owl

Tachycardia [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
type: NamedIndividual
Display_Name: Tachycardia
MeSH_CUI: M0020996
MeSH_DUI: D013610
MeSH_Definition: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
MeSH_Name: Tachycardia
NUI: N0000002888
RxNorm_CUI: 1023558
SNOMED_CID: 3424008
SNOMED_CID: 86651002
UMLS_CUI: C0039231
code: C5954
imported from: NDF-RT.owl

Tachycardia, Supraventricular [Disease/Finding]
type: Class
subclass of: Tachycardia [Disease/Finding]
type: NamedIndividual
Display_Name: Tachycardia, Supraventricular
MeSH_CUI: M0021006
MeSH_DUI: D013617
MeSH_Definition: A generic expression for any tachycardia that originates above the BUNDLE OF HIS.
MeSH_Name: Tachycardia, Supraventricular
NUI: N0000002895
RxNorm_CUI: 1022287
SNOMED_CID: 6456007
UMLS_CUI: C0039240
code: C5968
imported from: NDF-RT.owl

Tetanus [Disease/Finding]
type: Class
subclass of: Clostridium Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Tetanus
MeSH_CUI: M0021200
MeSH_DUI: D013742
MeSH_Definition: A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
MeSH_Name: Tetanus
NUI: N0000002915
RxNorm_CUI: 1022251
SNOMED_CID: 276202003
SNOMED_CID: 76902006
UMLS_CUI: C0039614
code: C6008
imported from: NDF-RT.owl

Thrombocythemia, Essential [Disease/Finding]
type: Class
subclass of: Blood Coagulation Disorders [Disease/Finding]
subclass of: Hemorrhagic Disorders [Disease/Finding]
subclass of: Thrombocytosis [Disease/Finding]
type: NamedIndividual
Display_Name: Thrombocythemia, Essential
MeSH_CUI: M0021427
MeSH_DUI: D013920
MeSH_Definition: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
MeSH_Name: Thrombocythemia, Essential
NUI: N0000002931
RxNorm_CUI: 1022170
SNOMED_CID: 109994006
Synonym: Hemorrhagic Thrombocythemia
Synonym: Thrombocythemia, Hemorrhagic
Synonym: Thrombocythemia, Idiopathic
Synonym: Thrombocythemia, Primary
UMLS_CUI: C0040028
code: C6040
imported from: NDF-RT.owl

Thrombocytopenia [Disease/Finding]
type: Class
subclass of: Blood Platelet Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Thrombocytopenia
MeSH_CUI: M0021428
MeSH_DUI: D013921
MeSH_Definition: A subnormal level of BLOOD PLATELETS.
MeSH_Name: Thrombocytopenia
NUI: N0000002932
RxNorm_CUI: 1024914
SNOMED_CID: 302215000
Synonym: Thrombopenia
UMLS_CUI: C0040034
code: C6042
imported from: NDF-RT.owl

Thrombocytosis [Disease/Finding]
type: Class
subclass of: Blood Platelet Disorders [Disease/Finding]
subclass of: Myeloproliferative Disorders [Disease/Finding]
Display_Name: Thrombocytosis
MeSH_CUI: M0021429
MeSH_DUI: D013922
MeSH_Definition: Increased numbers of platelets in the peripheral blood. (Dorland, 27th ed)
MeSH_Name: Thrombocytosis
NUI: N0000002933
RxNorm_CUI: 1022830
SNOMED_CID: 6631009
Synonym: Thrombocythemia
UMLS_CUI: C0836924
code: C6044
imported from: NDF-RT.owl

Thromboembolism [Disease/Finding]
type: Class
subclass of: Thrombosis [Disease/Finding]
type: NamedIndividual
Display_Name: Thromboembolism
MeSH_CUI: M0021430
MeSH_DUI: D013923
MeSH_Definition: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.
MeSH_Name: Thromboembolism
NUI: N0000002934
RxNorm_CUI: 1027317
SNOMED_CID: 371039008
UMLS_CUI: C0040038
code: C6046
imported from: NDF-RT.owl

Thrombophlebitis [Disease/Finding]
type: Class
subclass of: Phlebitis [Disease/Finding]
subclass of: Venous Thrombosis [Disease/Finding]
type: NamedIndividual
Display_Name: Thrombophlebitis
MeSH_CUI: M0021432
MeSH_DUI: D013924
MeSH_Definition: Inflammation of a vein associated with a blood clot (THROMBUS).
MeSH_Name: Thrombophlebitis
NUI: N0000002935
RxNorm_CUI: 1025289
SNOMED_CID: 64156001
UMLS_CUI: C0040046
code: C6048
imported from: NDF-RT.owl

Thrombosis [Disease/Finding]
type: Class
subclass of: Embolism and Thrombosis [Disease/Finding]
type: NamedIndividual
Display_Name: Thrombosis
MeSH_CUI: M0021435
MeSH_DUI: D013927
MeSH_Definition: Formation and development of a thrombus or blood clot in the blood vessel.
MeSH_Name: Thrombosis
NUI: N0000002936
RxNorm_CUI: 1022873
SNOMED_CID: 118927008
UMLS_CUI: C0040053
code: C6050
imported from: NDF-RT.owl

Tonsillitis [Disease/Finding]
type: Class
subclass of: Pharyngitis [Disease/Finding]
type: NamedIndividual
Display_Name: Tonsillitis
MeSH_CUI: M0021666
MeSH_DUI: D014069
MeSH_Definition: Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
MeSH_Name: Tonsillitis
NUI: N0000002969
RxNorm_CUI: 1023281
SNOMED_CID: 90176007
UMLS_CUI: C0040425
code: C6116
imported from: NDF-RT.owl

Trematode Infections [Disease/Finding]
type: Class
subclass of: Helminthiasis [Disease/Finding]
Display_Name: Trematode Infections
MeSH_CUI: M0021868
MeSH_DUI: D014201
MeSH_Definition: Infections caused by infestation with worms of the class Trematoda.
MeSH_Name: Trematode Infections
NUI: N0000003004
RxNorm_CUI: 1023326
SNOMED_CID: 26089000
Synonym: Infections, Trematode
UMLS_CUI: C0040820
code: C6186
imported from: NDF-RT.owl

Trichuriasis [Disease/Finding]
type: Class
subclass of: Enoplida Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Trichuriasis
MeSH_CUI: M0021941
MeSH_DUI: D014257
MeSH_Definition: Infection with nematodes of the genus TRICHURIS, formerly called Trichocephalus.
MeSH_Name: Trichuriasis
NUI: N0000003014
RxNorm_CUI: 1023521
SNOMED_CID: 3752003
SNOMED_CID: 60570001
Synonym: Trichocephaliasis
UMLS_CUI: C0040954
code: C6206
imported from: NDF-RT.owl

Tumor Virus Infections [Disease/Finding]
type: Class
subclass of: Neoplasms, Experimental [Disease/Finding]
subclass of: DOID 934
Display_Name: Tumor Virus Infections
MeSH_CUI: M0022156
MeSH_DUI: D014412
MeSH_Definition: Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses.
MeSH_Name: Tumor Virus Infections
NUI: N0000003056
RxNorm_CUI: 988538
Synonym: Infections, Tumor Virus
UMLS_CUI: C0041374
code: C6290
imported from: NDF-RT.owl

Unconsciousness [Disease/Finding]
type: Class
subclass of: Consciousness Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Unconsciousness
MeSH_CUI: M0022251
MeSH_DUI: D014474
MeSH_Definition: Loss of the ability to maintain awareness of self and environment combined with markedly reduced responsiveness to environmental stimuli. (From Adams et al., Principles of Neurology, 6th ed, pp344-5)
MeSH_Name: Unconsciousness
NUI: N0000003064
RxNorm_CUI: 1026031
SNOMED_CID: 418107008
SNOMED_CID: 419045004
Synonym: Consciousness, Loss of
Synonym: Unconscious State
UMLS_CUI: C0041657
code: C6306
imported from: NDF-RT.owl

Urethral Diseases [Disease/Finding]
type: Class
subclass of: Urologic Diseases [Disease/Finding]
Display_Name: Urethral Diseases
MeSH_CUI: M0022332
MeSH_DUI: D014522
MeSH_Definition: Pathological processes involving the URETHRA.
MeSH_Name: Urethral Diseases
NUI: N0000003072
RxNorm_CUI: 1022102
SNOMED_CID: 4985009
UMLS_CUI: C0041969
code: C6322
imported from: NDF-RT.owl

Urethral Obstruction [Disease/Finding]
type: Class
subclass of: Urethral Diseases [Disease/Finding]
Display_Name: Urethral Obstruction
MeSH_CUI: M0022334
MeSH_DUI: D014524
MeSH_Definition: Partial or complete blockage in any part of the URETHRA that can lead to difficulty or inability to empty the URINARY BLADDER. It is characterized by an enlarged, often damaged, bladder with frequent urges to void.
MeSH_Name: Urethral Obstruction
NUI: N0000003074
RxNorm_CUI: 985086
SNOMED_CID: 95588004
UMLS_CUI: C0041972
code: C6326
imported from: NDF-RT.owl

Urethritis [Disease/Finding]
type: Class
subclass of: Urethral Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Urethritis
MeSH_CUI: M0022336
MeSH_DUI: D014526
MeSH_Definition: Inflammation involving the URETHRA. Similar to CYSTITIS, clinical symptoms range from vague discomfort to painful urination (DYSURIA), urethral discharge, or both.
MeSH_Name: Urethritis
NUI: N0000003076
RxNorm_CUI: 1025450
SNOMED_CID: 197905005
SNOMED_CID: 31822004
UMLS_CUI: C0041976
code: C6330
imported from: NDF-RT.owl

Urogenital Neoplasms [Disease/Finding]
type: Class
subclass of: Neoplasms by Site [Disease/Finding]
subclass of: Male Urogenital Diseases [Disease/Finding]
subclass of: Female Urogenital Diseases [Disease/Finding]
Display_Name: Urogenital Neoplasms
MeSH_CUI: M0022391
MeSH_DUI: D014565
MeSH_Definition: Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.
MeSH_Name: Urogenital Neoplasms
NUI: N0000003084
RxNorm_CUI: 1025116
Synonym: Genito-urinary Neoplasm
Synonym: Genitourinary Neoplasms
Synonym: Neoplasms, Genitourinary
Synonym: Neoplasms, Urogenital
UMLS_CUI: C0042065
code: C6346
imported from: NDF-RT.owl

Male Urogenital Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Male Urogenital Diseases
MeSH_CUI: M0489510
MeSH_DUI: D052801
MeSH_Definition: Pathological processes of the male URINARY TRACT and the reproductive system (GENITALIA, MALE).
MeSH_Name: Male Urogenital Diseases
NUI: N0000003085
RxNorm_CUI: 1027597
Synonym: Male Genitourinary Diseases
UMLS_CUI: C1720894
code: CMSHM0489510
imported from: NDF-RT.owl

Urologic Diseases [Disease/Finding]
type: Class
subclass of: Male Urogenital Diseases [Disease/Finding]
subclass of: Female Urogenital Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Urologic Diseases
MeSH_CUI: M0022400
MeSH_DUI: D014570
MeSH_Definition: Pathological processes of the URINARY TRACT in both males and females.
MeSH_Name: Urologic Diseases
NUI: N0000003086
RxNorm_CUI: 1022769
SNOMED_CID: 128606002
SNOMED_CID: 197951006
SNOMED_CID: 41368006
Synonym: Urinary Tract Diseases
Synonym: Urological Diseases
UMLS_CUI: C0042075
code: C6350
imported from: NDF-RT.owl

Urologic Neoplasms [Disease/Finding]
type: Class
subclass of: Urogenital Neoplasms [Disease/Finding]
Display_Name: Urologic Neoplasms
MeSH_CUI: M0022401
MeSH_DUI: D014571
MeSH_Definition: Tumors or cancer of the URINARY TRACT in either the male or the female.
MeSH_Name: Urologic Neoplasms
NUI: N0000003087
RxNorm_CUI: 1023305
SNOMED_CID: 126879004
SNOMED_CID: 254913005
Synonym: Neoplasms, Urologic
Synonym: Urinary Tract Neoplasms
Synonym: Urological Neoplasms
UMLS_CUI: C0042076
code: C6352
imported from: NDF-RT.owl

Urticaria [Disease/Finding]
type: Class
subclass of: Hypersensitivity, Immediate [Disease/Finding]
subclass of: Skin Diseases, Vascular [Disease/Finding]
type: NamedIndividual
Display_Name: Urticaria
MeSH_CUI: M0022414
MeSH_DUI: D014581
MeSH_Definition: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
MeSH_Name: Urticaria
NUI: N0000003088
RxNorm_CUI: 1023461
SNOMED_CID: 126485001
Synonym: Hives
UMLS_CUI: C0042109
code: C6354
imported from: NDF-RT.owl

Uterine Diseases [Disease/Finding]
type: Class
subclass of: Genital Diseases, Female [Disease/Finding]
type: NamedIndividual
Display_Name: Uterine Diseases
MeSH_CUI: M0022426
MeSH_DUI: D014591
MeSH_Definition: Pathological processes involving any part of the UTERUS.
MeSH_Name: Uterine Diseases
NUI: N0000003090
RxNorm_CUI: 1025904
SNOMED_CID: 12337004
UMLS_CUI: C0042131
code: C6358
imported from: NDF-RT.owl

Uterine Hemorrhage [Disease/Finding]
type: Class
subclass of: Hemorrhage [Disease/Finding]
subclass of: Uterine Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Uterine Hemorrhage
MeSH_CUI: M0022428
MeSH_DUI: D014592
MeSH_Definition: Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.
MeSH_Name: Uterine Hemorrhage
NUI: N0000003091
RxNorm_CUI: 1024627
SNOMED_CID: 38280009
Synonym: Hemorrhage, Uterine
Synonym: Uterine Bleeding
UMLS_CUI: C0042134
code: C6360
imported from: NDF-RT.owl

Uterine Neoplasms [Disease/Finding]
type: Class
subclass of: Genital Neoplasms, Female [Disease/Finding]
subclass of: Uterine Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Uterine Neoplasms
MeSH_CUI: M0022431
MeSH_DUI: D014594
MeSH_Definition: Tumors or cancer of the UTERUS.
MeSH_Name: Uterine Neoplasms
NUI: N0000003093
RxNorm_CUI: 1022983
SNOMED_CID: 126908007
Synonym: Neoplasms, Uterine
Synonym: Neoplasms, Uterus
Synonym: Uterus Neoplasms
UMLS_CUI: C0042138
code: C6364
imported from: NDF-RT.owl

Vaginal Diseases [Disease/Finding]
type: Class
subclass of: Genital Diseases, Female [Disease/Finding]
Display_Name: Vaginal Diseases
MeSH_CUI: M0022482
MeSH_DUI: D014623
MeSH_Definition: Pathological processes of the VAGINA.
MeSH_Name: Vaginal Diseases
NUI: N0000003104
RxNorm_CUI: 1026314
SNOMED_CID: 25658005
UMLS_CUI: C0042251
code: C6386
imported from: NDF-RT.owl

Vaginitis [Disease/Finding]
type: Class
subclass of: Vaginal Diseases [Disease/Finding]
Display_Name: Vaginitis
MeSH_CUI: M0022488
MeSH_DUI: D014627
MeSH_Definition: Inflammation of the vagina characterized by pain and a purulent discharge.
MeSH_Name: Vaginitis
NUI: N0000003107
RxNorm_CUI: 1021851
SNOMED_CID: 198213001
SNOMED_CID: 30800001
UMLS_CUI: C0042267
code: C6392
imported from: NDF-RT.owl

Vascular Diseases [Disease/Finding]
type: Class
subclass of: Cardiovascular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Vascular Diseases
MeSH_CUI: M0022535
MeSH_DUI: D014652
MeSH_Definition: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
MeSH_Name: Vascular Diseases
NUI: N0000003111
RxNorm_CUI: 1024109
SNOMED_CID: 27550009
UMLS_CUI: C0042373
code: C6400
imported from: NDF-RT.owl

Vasculitis [Disease/Finding]
type: Class
subclass of: Vascular Diseases [Disease/Finding]
Display_Name: Vasculitis
MeSH_CUI: M0022540
MeSH_DUI: D014657
MeSH_Definition: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.
MeSH_Name: Vasculitis
NUI: N0000003113
RxNorm_CUI: 1026759
SNOMED_CID: 31996006
Synonym: Angiitis
UMLS_CUI: C0042384
code: C6404
imported from: NDF-RT.owl

Ventricular Fibrillation [Disease/Finding]
type: Class
subclass of: Arrhythmias, Cardiac [Disease/Finding]
type: NamedIndividual
Display_Name: Ventricular Fibrillation
MeSH_CUI: M0022595
MeSH_DUI: D014693
MeSH_Definition: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
MeSH_Name: Ventricular Fibrillation
NUI: N0000003118
RxNorm_CUI: 1024218
SNOMED_CID: 71908006
UMLS_CUI: C0042510
code: C6414
imported from: NDF-RT.owl

Ventricular Outflow Obstruction [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
Display_Name: Ventricular Outflow Obstruction
MeSH_CUI: M0022598
MeSH_DUI: D014694
MeSH_Definition: Occlusion of the outflow tract in either the LEFT VENTRICLE or the RIGHT VENTRICLE of the heart. This may result from CONGENITAL HEART DEFECTS, predisposing heart diseases, complications of surgery, or HEART NEOPLASMS.
MeSH_Name: Ventricular Outflow Obstruction
NUI: N0000003119
RxNorm_CUI: 1028258
UMLS_CUI: C0042512
code: C6416
imported from: NDF-RT.owl

Vertigo [Disease/Finding]
type: Class
subclass of: Neurologic Manifestations [Disease/Finding]
subclass of: Vestibular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Vertigo
MeSH_CUI: M0022633
MeSH_DUI: D014717
MeSH_Definition: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)
MeSH_Name: Vertigo
NUI: N0000003121
RxNorm_CUI: 1023692
SNOMED_CID: 271792009
Synonym: Spinning Sensation
Synonym: Vertigo, Subjective
UMLS_CUI: C0042571
code: C6420
imported from: NDF-RT.owl

Vision Disorders [Disease/Finding]
type: Class
subclass of: Eye Diseases [Disease/Finding]
subclass of: Sensation Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Vision Disorders
MeSH_CUI: M0022771
MeSH_DUI: D014786
MeSH_Definition: Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from EYE DISEASES; OPTIC NERVE DISEASES; VISUAL PATHWAY diseases; OCCIPITAL LOBE diseases; OCULAR MOTILITY DISORDERS; and other conditions. Visual disability refers to inability of the individual to perform specific visual tasks, such as reading, writing, orientation, or traveling unaided. (From Newell, Ophthalmology: Principles and Concepts, 7th ed, p132)
MeSH_Name: Vision Disorders
NUI: N0000003130
RxNorm_CUI: 1023787
SNOMED_CID: 128127008
SNOMED_CID: 95677002
UMLS_CUI: C0042790
code: C6438
imported from: NDF-RT.owl

Vomiting [Disease/Finding]
type: Class
subclass of: Signs and Symptoms, Digestive [Disease/Finding]
type: NamedIndividual
Display_Name: Vomiting
MeSH_CUI: M0022844
MeSH_DUI: D014839
MeSH_Definition: The forcible expulsion of the contents of the STOMACH through the MOUTH.
MeSH_Name: Vomiting
NUI: N0000003141
RxNorm_CUI: 1025810
SNOMED_CID: 15387003
Synonym: Emesis
UMLS_CUI: C0042963
code: C6460
imported from: NDF-RT.owl

Vulvar Diseases [Disease/Finding]
type: Class
subclass of: Genital Diseases, Female [Disease/Finding]
Display_Name: Vulvar Diseases
MeSH_CUI: M0022856
MeSH_DUI: D014845
MeSH_Definition: Pathological processes of the VULVA.
MeSH_Name: Vulvar Diseases
NUI: N0000003145
RxNorm_CUI: 1024723
SNOMED_CID: 5089007
UMLS_CUI: C0042994
code: C6468
imported from: NDF-RT.owl

Vulvitis [Disease/Finding]
type: Class
subclass of: Vulvar Diseases [Disease/Finding]
Display_Name: Vulvitis
MeSH_CUI: M0022858
MeSH_DUI: D014847
MeSH_Definition: Inflammation of the VULVA. It is characterized by PRURITUS and painful urination.
MeSH_Name: Vulvitis
NUI: N0000003147
RxNorm_CUI: 1023099
SNOMED_CID: 266586003
SNOMED_CID: 63144007
UMLS_CUI: C0042996
code: C6472
imported from: NDF-RT.owl

Vulvovaginitis [Disease/Finding]
type: Class
subclass of: Vaginitis [Disease/Finding]
subclass of: Vulvitis [Disease/Finding]
Display_Name: Vulvovaginitis
MeSH_CUI: M0022859
MeSH_DUI: D014848
MeSH_Definition: Inflammation of the VULVA and the VAGINA, characterized by discharge, burning, and PRURITUS.
MeSH_Name: Vulvovaginitis
NUI: N0000003148
RxNorm_CUI: 1025805
SNOMED_CID: 198215008
SNOMED_CID: 53277000
UMLS_CUI: C0042998
code: C6474
imported from: NDF-RT.owl

Warts [Disease/Finding]
type: Class
subclass of: Skin Diseases, Viral [Disease/Finding]
subclass of: Papillomavirus Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Warts
MeSH_CUI: M0022875
MeSH_DUI: D014860
MeSH_Definition: Benign epidermal proliferations or tumors; some are viral in origin.
MeSH_Name: Warts
NUI: N0000003152
RxNorm_CUI: 1022255
SNOMED_CID: 57019003
Synonym: Verruca
UMLS_CUI: C0043037
code: C6482
imported from: NDF-RT.owl

West Nile Fever [Disease/Finding]
type: Class
subclass of: Encephalitis, Arbovirus [Disease/Finding]
subclass of: Flavivirus Infections [Disease/Finding]
Display_Name: West Nile Fever
MeSH_CUI: M0022928
MeSH_DUI: D014901
MeSH_Definition: A mosquito-borne viral illness caused by the WEST NILE VIRUS, a FLAVIVIRUS and endemic to regions of Africa, Asia, and Europe. Common clinical features include HEADACHE; FEVER; maculopapular rash; gastrointestinal symptoms; and lymphadenopathy. MENINGITIS; ENCEPHALITIS; and MYELITIS may also occur. The disease may occasionally be fatal or leave survivors with residual neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13; Lancet 1998 Sep 5;352(9130):767-71)
MeSH_Name: West Nile Fever
NUI: N0000003161
RxNorm_CUI: 1024531
UMLS_CUI: C0043124
code: C6500
imported from: NDF-RT.owl

Wolff-Parkinson-White Syndrome [Disease/Finding]
type: Class
subclass of: Heart Defects, Congenital [Disease/Finding]
subclass of: Pre-Excitation Syndromes [Disease/Finding]
type: NamedIndividual
Display_Name: Wolff-Parkinson-White Syndrome
MeSH_CUI: M0022990
MeSH_DUI: D014927
MeSH_Definition: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
MeSH_Name: Wolff-Parkinson-White Syndrome
NUI: N0000003166
RxNorm_CUI: 1023880
SNOMED_CID: 74390002
Synonym: Anomalous Ventricular Excitation Syndrome
Synonym: Auriculoventricular Accessory Pathway Syndrome
Synonym: False Bundle-Branch Block Syndrome
Synonym: WPW Syndrome
Synonym: Wolf-Parkinson-White Syndrome
UMLS_CUI: C0043202
code: C6510
imported from: NDF-RT.owl

Esophageal Motility Disorders [Disease/Finding]
type: Class
subclass of: Deglutition Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Esophageal Motility Disorders
MeSH_CUI: M0023297
MeSH_DUI: D015154
MeSH_Definition: Disorders affecting the motor function of the UPPER ESOPHAGEAL SPHINCTER; LOWER ESOPHAGEAL SPHINCTER; the ESOPHAGUS body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (GASTROESOPHAGEAL REFLUX). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus).
MeSH_Name: Esophageal Motility Disorders
NUI: N0000003189
RxNorm_CUI: 1022716
SNOMED_CID: 266434009
Synonym: Esophageal Dysmotility
UMLS_CUI: C0014858
code: C6556
imported from: NDF-RT.owl

Colorectal Neoplasms [Disease/Finding]
type: Class
subclass of: Colonic Diseases [Disease/Finding]
subclass of: Intestinal Neoplasms [Disease/Finding]
subclass of: Rectal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Colorectal Neoplasms
MeSH_CUI: M0023329
MeSH_DUI: D015179
MeSH_Definition: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
MeSH_Name: Colorectal Neoplasms
NUI: N0000003198
RxNorm_CUI: 1022247
SNOMED_CID: 126837005
Synonym: Colorectal Tumors
Synonym: Neoplasms, Colorectal
UMLS_CUI: C0009404
code: C6574
imported from: NDF-RT.owl

Inflammatory Bowel Diseases [Disease/Finding]
type: Class
subclass of: Gastroenteritis [Disease/Finding]
subclass of: Intestinal Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Inflammatory Bowel Diseases
MeSH_CUI: M0023374
MeSH_DUI: D015212
MeSH_Definition: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
MeSH_Name: Inflammatory Bowel Diseases
NUI: N0000003206
RxNorm_CUI: 1023128
SNOMED_CID: 24526004
Synonym: Bowel Diseases, Inflammatory
UMLS_CUI: C0021390
code: C6590
imported from: NDF-RT.owl

Sexually Transmitted Diseases, Viral [Disease/Finding]
type: Class
subclass of: Sexually Transmitted Diseases [Disease/Finding]
Display_Name: Sexually Transmitted Diseases, Viral
MeSH_CUI: M0023402
MeSH_DUI: D015229
MeSH_Definition: Viral diseases which are transmitted or propagated by sexual conduct.
MeSH_Name: Sexually Transmitted Diseases, Viral
NUI: N0000003211
RxNorm_CUI: 1027279
Synonym: Sexually Transmitted Disease, Viral
Synonym: Venereal Diseases, Viral
Synonym: Viral Sexually Transmitted Disease
Synonym: Viral Sexually Transmitted Diseases
Synonym: Viral Venereal Diseases
UMLS_CUI: C0036918
code: C6600
imported from: NDF-RT.owl

Sexually Transmitted Diseases, Bacterial [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
subclass of: Sexually Transmitted Diseases [Disease/Finding]
Display_Name: Sexually Transmitted Diseases, Bacterial
MeSH_CUI: M0023404
MeSH_DUI: D015231
MeSH_Definition: Bacterial diseases transmitted or propagated by sexual conduct.
MeSH_Name: Sexually Transmitted Diseases, Bacterial
NUI: N0000003212
RxNorm_CUI: 1027541
Synonym: Bacterial Sexually Transmitted Disease
Synonym: Bacterial Sexually Transmitted Diseases
Synonym: Bacterial Venereal Diseases
Synonym: Sexually Transmitted Disease, Bacterial
Synonym: Venereal Diseases, Bacterial
UMLS_CUI: C0036917
code: C6602
imported from: NDF-RT.owl

Leukemia, Myelogenous, Chronic, BCR-ABL Positive [Disease/Finding]
type: Class
subclass of: Leukemia, Myeloid [Disease/Finding]
subclass of: Myeloproliferative Disorders [Disease/Finding]
Display_Name: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
MeSH_CUI: M0023821
MeSH_DUI: D015464
MeSH_Definition: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
MeSH_Name: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
NUI: N0000003261
RxNorm_CUI: 1021752
SNOMED_CID: 92818009
Synonym: Granulocytic Leukemia, Chronic
Synonym: Leukemia, Granulocytic, Chronic
Synonym: Leukemia, Myelocytic, Chronic
Synonym: Leukemia, Myelogenous, Chronic
Synonym: Leukemia, Myelogenous, Ph1 Positive
Synonym: Leukemia, Myelogenous, Ph1-Positive
Synonym: Leukemia, Myeloid, Chronic
Synonym: Leukemia, Myeloid, Ph1 Positive
Synonym: Leukemia, Myeloid, Ph1-Positive
Synonym: Leukemia, Myeloid, Philadelphia Positive
Synonym: Leukemia, Myeloid, Philadelphia-Positive
Synonym: Myelocytic Leukemia, Chronic
Synonym: Myelogenous Leukemia, Chronic
Synonym: Myelogenous Leukemia, Ph1-Positive
Synonym: Myeloid Leukemia, Chronic
Synonym: Myeloid Leukemia, Ph1-Positive
Synonym: Myeloid Leukemia, Philadelphia-Positive
UMLS_CUI: C0023473
code: C6700
imported from: NDF-RT.owl

Leukemia, Myeloid, Accelerated Phase [Disease/Finding]
type: Class
subclass of: Leukemia, Myelogenous, Chronic, BCR-ABL Positive [Disease/Finding]
type: NamedIndividual
Display_Name: Leukemia, Myeloid, Accelerated Phase
MeSH_CUI: M0023822
MeSH_DUI: D015465
MeSH_Definition: The phase of chronic myeloid leukemia following the chronic phase (LEUKEMIA, MYELOID, CHRONIC-PHASE), where there are increased systemic symptoms, worsening cytopenias, and refractory LEUKOCYTOSIS.
MeSH_Name: Leukemia, Myeloid, Accelerated Phase
NUI: N0000003262
RxNorm_CUI: 989240
SNOMED_CID: 413389003
Synonym: Leukemia, Myelogenous, Aggressive Phase
Synonym: Leukemia, Myelogenous, Aggressive-Phase
Synonym: Leukemia, Myeloid, Accelerated-Phase
Synonym: Leukemia, Myeloid, Aggressive-Phase
Synonym: Myelogenous Leukemia, Chronic, Aggressive Phase
Synonym: Myelogenous Leukemia, Chronic, Aggressive-Phase
Synonym: Myeloid Leukemia, Chronic, Accelerated Phase
Synonym: Myeloid Leukemia, Chronic, Accelerated-Phase
Synonym: Myeloid Leukemia, Chronic, Aggressive Phase
Synonym: Myeloid Leukemia, Chronic, Aggressive-Phase
UMLS_CUI: C0023472
code: C6702
imported from: NDF-RT.owl

HIV Infections [Disease/Finding]
type: Class
subclass of: Immunologic Deficiency Syndromes [Disease/Finding]
subclass of: Sexually Transmitted Diseases, Viral [Disease/Finding]
subclass of: Lentivirus Infections [Disease/Finding]
Display_Name: HIV Infections
MeSH_CUI: M0023997
MeSH_DUI: D015658
MeSH_Definition: Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
MeSH_Name: HIV Infections
NUI: N0000003302
RxNorm_CUI: 1022756
SNOMED_CID: 86406008
Synonym: HTLV-III Infections
Synonym: HTLV-III-LAV Infections
Synonym: T-Lymphotropic Virus Type III Infections, Human
UMLS_CUI: C0019693
code: C6782
imported from: NDF-RT.owl

Vestibular Diseases [Disease/Finding]
type: Class
subclass of: Labyrinth Diseases [Disease/Finding]
Display_Name: Vestibular Diseases
MeSH_CUI: M0024253
MeSH_DUI: D015837
MeSH_Definition: Pathological processes of the VESTIBULAR LABYRINTH which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.
MeSH_Name: Vestibular Diseases
NUI: N0000003336
RxNorm_CUI: 1026474
SNOMED_CID: 20425006
UMLS_CUI: C0042594
code: C6850
imported from: NDF-RT.owl

Lentivirus Infections [Disease/Finding]
type: Class
subclass of: Retroviridae Infections [Disease/Finding]
Display_Name: Lentivirus Infections
MeSH_CUI: M0024697
MeSH_DUI: D016180
MeSH_Definition: Virus diseases caused by the Lentivirus genus. They are multi-organ diseases characterized by long incubation periods and persistent infection.
MeSH_Name: Lentivirus Infections
NUI: N0000003384
RxNorm_CUI: 1024090
SNOMED_CID: 24907000
Synonym: Infections, Lentivirus
UMLS_CUI: C0079680
code: C6946
imported from: NDF-RT.owl

Lymphoma, T-Cell [Disease/Finding]
type: Class
subclass of: Lymphoma, Non-Hodgkin [Disease/Finding]
Display_Name: Lymphoma, T-Cell
MeSH_CUI: M0025079
MeSH_DUI: D016399
MeSH_Definition: A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.
MeSH_Name: Lymphoma, T-Cell
NUI: N0000003398
RxNorm_CUI: 1023910
SNOMED_CID: 109978004
Synonym: T-Cell Lymphoma
UMLS_CUI: C0079772
code: C6974
imported from: NDF-RT.owl

Lymphoma, T-Cell, Cutaneous [Disease/Finding]
type: Class
subclass of: Lymphoma, T-Cell [Disease/Finding]
Display_Name: Lymphoma, T-Cell, Cutaneous
MeSH_CUI: M0025093
MeSH_DUI: D016410
MeSH_Definition: A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders.
MeSH_Name: Lymphoma, T-Cell, Cutaneous
NUI: N0000003409
RxNorm_CUI: 1025184
SNOMED_CID: 400122007
Synonym: Cutaneous T-Cell Lymphoma
Synonym: Lymphoma, T Cell, Cutaneous
Synonym: T-Cell Lymphoma, Cutaneous
UMLS_CUI: C0079773
code: C6996
imported from: NDF-RT.owl

Peripheral Vascular Diseases [Disease/Finding]
type: Class
subclass of: Vascular Diseases [Disease/Finding]
Display_Name: Peripheral Vascular Diseases
MeSH_CUI: M0025176
MeSH_DUI: D016491
MeSH_Definition: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.
MeSH_Name: Peripheral Vascular Diseases
NUI: N0000003422
RxNorm_CUI: 1022504
SNOMED_CID: 400047006
Synonym: Diseases, Peripheral Vascular
Synonym: Peripheral Angiopathies
Synonym: Vascular Diseases, Peripheral
UMLS_CUI: C0085096
code: C7022
imported from: NDF-RT.owl

Central Nervous System Neoplasms [Disease/Finding]
type: Class
subclass of: Nervous System Neoplasms [Disease/Finding]
Display_Name: Central Nervous System Neoplasms
MeSH_CUI: M0025244
MeSH_DUI: D016543
MeSH_Definition: Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.
MeSH_Name: Central Nervous System Neoplasms
NUI: N0000003434
RxNorm_CUI: 1025007
SNOMED_CID: 126951006
Synonym: Central Nervous System Tumors
Synonym: Neoplasms, Central Nervous System
Synonym: Tumors, Central Nervous System
UMLS_CUI: C0085136
code: C7046
imported from: NDF-RT.owl

Panic Disorder [Disease/Finding]
type: Class
subclass of: Anxiety Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Panic Disorder
MeSH_CUI: M0025297
MeSH_DUI: D016584
MeSH_Definition: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
MeSH_Name: Panic Disorder
NUI: N0000003442
RxNorm_CUI: 1022562
SNOMED_CID: 371631005
UMLS_CUI: C0030319
code: C7062
imported from: NDF-RT.owl

Embolism and Thrombosis [Disease/Finding]
type: Class
subclass of: Vascular Diseases [Disease/Finding]
Display_Name: Embolism and Thrombosis
MeSH_CUI: M0025559
MeSH_DUI: D016769
MeSH_Definition: A collective term for pathological conditions which are caused by the formation of a blood clot (THROMBUS) in a blood vessel, or by blocking of a blood vessel with an EMBOLUS, undissolved materials in the blood stream.
MeSH_Name: Embolism and Thrombosis
NUI: N0000003473
RxNorm_CUI: 1031715
SNOMED_CID: 195440003
UMLS_CUI: C0085307
code: C7124
imported from: NDF-RT.owl

Malaria, Falciparum [Disease/Finding]
type: Class
subclass of: Malaria [Disease/Finding]
type: NamedIndividual
Display_Name: Malaria, Falciparum
MeSH_CUI: M0025570
MeSH_DUI: D016778
MeSH_Definition: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
MeSH_Name: Malaria, Falciparum
NUI: N0000003481
RxNorm_CUI: 1023574
SNOMED_CID: 62676009
Synonym: Plasmodium falciparum Malaria
UMLS_CUI: C0024535
code: C7140
imported from: NDF-RT.owl

Malaria, Vivax [Disease/Finding]
type: Class
subclass of: Malaria [Disease/Finding]
type: NamedIndividual
Display_Name: Malaria, Vivax
MeSH_CUI: M0025572
MeSH_DUI: D016780
MeSH_Definition: Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.
MeSH_Name: Malaria, Vivax
NUI: N0000003483
RxNorm_CUI: 1022708
SNOMED_CID: 27052006
Synonym: Plasmodium vivax Malaria
UMLS_CUI: C0024537
code: C7144
imported from: NDF-RT.owl

Neisseriaceae Infections [Disease/Finding]
type: Class
subclass of: Gram-Negative Bacterial Infections [Disease/Finding]
Display_Name: Neisseriaceae Infections
MeSH_CUI: M0025673
MeSH_DUI: D016870
MeSH_Definition: Infections with bacteria of the family NEISSERIACEAE.
MeSH_Name: Neisseriaceae Infections
NUI: N0000003493
RxNorm_CUI: 1025935
Synonym: Infections, Neisseriaceae
UMLS_CUI: C0085396
code: C7164
imported from: NDF-RT.owl

Pasteurellaceae Infections [Disease/Finding]
type: Class
subclass of: Gram-Negative Bacterial Infections [Disease/Finding]
Display_Name: Pasteurellaceae Infections
MeSH_CUI: M0025674
MeSH_DUI: D016871
MeSH_Definition: Infections with bacteria of the family PASTEURELLACEAE.
MeSH_Name: Pasteurellaceae Infections
NUI: N0000003494
RxNorm_CUI: 985866
Synonym: Infections, Pasteurellaceae
UMLS_CUI: C0085397
code: C7166
imported from: NDF-RT.owl

Gram-Negative Bacterial Infections [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
Display_Name: Gram-Negative Bacterial Infections
MeSH_CUI: M0025725
MeSH_DUI: D016905
MeSH_Definition: Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.
MeSH_Name: Gram-Negative Bacterial Infections
NUI: N0000003506
RxNorm_CUI: 1023284
Synonym: Bacterial Infections, Gram-Negative
Synonym: Infections, Gram-Negative Bacterial
UMLS_CUI: C0085423
code: C7190
imported from: NDF-RT.owl

Gram-Positive Bacterial Infections [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
Display_Name: Gram-Positive Bacterial Infections
MeSH_CUI: M0025728
MeSH_DUI: D016908
MeSH_Definition: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
MeSH_Name: Gram-Positive Bacterial Infections
NUI: N0000003507
RxNorm_CUI: 1022700
Synonym: Bacterial Infections, Gram-Positive
Synonym: Infections, Gram-Positive Bacterial
UMLS_CUI: C0085426
code: C7192
imported from: NDF-RT.owl

Porphyrias, Hepatic [Disease/Finding]
type: Class
subclass of: Liver Diseases [Disease/Finding]
subclass of: Porphyrias [Disease/Finding]
subclass of: Skin Diseases, Genetic [Disease/Finding]
Display_Name: Porphyrias, Hepatic
MeSH_CUI: M0025973
MeSH_DUI: D017094
MeSH_Definition: A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
MeSH_Name: Porphyrias, Hepatic
NUI: N0000003528
RxNorm_CUI: 1024983
SNOMED_CID: 55056006
Synonym: Hepatic Porphyria
Synonym: Porphyria, Hepatic
UMLS_CUI: C0162533
code: C7234
imported from: NDF-RT.owl

Kidney Failure [Disease/Finding]
type: Class
subclass of: Renal Insufficiency [Disease/Finding]
type: NamedIndividual
Display_Name: Kidney Failure
MeSH_CUI: M0025974
MeSH_DUI: D051437
MeSH_Definition: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
MeSH_Name: Kidney Failure
NUI: N0000003529
RxNorm_CUI: 1022860
SNOMED_CID: 266553002
SNOMED_CID: 42399005
Synonym: Renal Failure
UMLS_CUI: C0035078
code: C7236
imported from: NDF-RT.owl

Porphyria, Acute Intermittent [Disease/Finding]
type: Class
subclass of: Porphyrias, Hepatic [Disease/Finding]
type: NamedIndividual
Display_Name: Porphyria, Acute Intermittent
MeSH_CUI: M0026010
MeSH_DUI: D017118
MeSH_Definition: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
MeSH_Name: Porphyria, Acute Intermittent
NUI: N0000003536
RxNorm_CUI: 1023116
SNOMED_CID: 234422006
Synonym: Acute Porphyria
UMLS_CUI: C0162565
code: C7250
imported from: NDF-RT.owl

Porphyria Cutanea Tarda [Disease/Finding]
type: Class
subclass of: Porphyrias, Hepatic [Disease/Finding]
type: NamedIndividual
Display_Name: Porphyria Cutanea Tarda
MeSH_CUI: M0026011
MeSH_DUI: D017119
MeSH_Definition: An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
MeSH_Name: Porphyria Cutanea Tarda
NUI: N0000003537
RxNorm_CUI: 1025616
SNOMED_CID: 61860000
UMLS_CUI: C0162566
code: C7252
imported from: NDF-RT.owl

Tachycardia, Ventricular [Disease/Finding]
type: Class
subclass of: Tachycardia [Disease/Finding]
type: NamedIndividual
Display_Name: Tachycardia, Ventricular
MeSH_CUI: M0026083
MeSH_DUI: D017180
MeSH_Definition: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
MeSH_Name: Tachycardia, Ventricular
NUI: N0000003541
RxNorm_CUI: 1023929
SNOMED_CID: 25569003
Synonym: Ventricular Tachycardia
UMLS_CUI: C0042514
code: C7260
imported from: NDF-RT.owl

Adenophorea Infections [Disease/Finding]
type: Class
subclass of: Nematode Infections [Disease/Finding]
Display_Name: Adenophorea Infections
MeSH_CUI: M0026092
MeSH_DUI: D017188
MeSH_Definition: Infections with nematodes of the subclass ADENOPHOREA.
MeSH_Name: Adenophorea Infections
NUI: N0000003542
RxNorm_CUI: 1023621
Synonym: Aphasmidia Infections
Synonym: Infections, Adenophorea
Synonym: Infections, Aphasmidia
UMLS_CUI: C0162623
code: C7262
imported from: NDF-RT.owl

Enoplida Infections [Disease/Finding]
type: Class
subclass of: Adenophorea Infections [Disease/Finding]
Display_Name: Enoplida Infections
MeSH_CUI: M0026094
MeSH_DUI: D017189
MeSH_Definition: Infections with nematodes of the order ENOPLIDA.
MeSH_Name: Enoplida Infections
NUI: N0000003543
RxNorm_CUI: 1022471
Synonym: Infections, Enoplida
UMLS_CUI: C0162624
code: C7264
imported from: NDF-RT.owl

Secernentea Infections [Disease/Finding]
type: Class
subclass of: Nematode Infections [Disease/Finding]
Display_Name: Secernentea Infections
MeSH_CUI: M0026095
MeSH_DUI: D017190
MeSH_Definition: Infections with nematodes of the subclass SECERNENTEA.
MeSH_Name: Secernentea Infections
NUI: N0000003544
RxNorm_CUI: 1026460
Synonym: Infections, Phasmidia
Synonym: Infections, Secernentea
Synonym: Phasmidia Infections
UMLS_CUI: C0162625
code: C7266
imported from: NDF-RT.owl

Ascaridida Infections [Disease/Finding]
type: Class
subclass of: Secernentea Infections [Disease/Finding]
Display_Name: Ascaridida Infections
MeSH_CUI: M0026096
MeSH_DUI: D017191
MeSH_Definition: Infections with nematodes of the order ASCARIDIDA.
MeSH_Name: Ascaridida Infections
NUI: N0000003545
RxNorm_CUI: 1028907
Synonym: Infections, Ascaridida
UMLS_CUI: C0162626
code: C7268
imported from: NDF-RT.owl

Skin Diseases, Bacterial [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
subclass of: Skin Diseases, Infectious [Disease/Finding]
Display_Name: Skin Diseases, Bacterial
MeSH_CUI: M0026097
MeSH_DUI: D017192
MeSH_Definition: Skin diseases caused by bacteria.
MeSH_Name: Skin Diseases, Bacterial
NUI: N0000003546
RxNorm_CUI: 984383
SNOMED_CID: 128936008
Synonym: Bacterial Skin Diseases
UMLS_CUI: C0162627
code: C7270
imported from: NDF-RT.owl

Skin Diseases, Viral [Disease/Finding]
type: Class
subclass of: Skin Diseases, Infectious [Disease/Finding]
subclass of: DOID 934
Display_Name: Skin Diseases, Viral
MeSH_CUI: M0026098
MeSH_DUI: D017193
MeSH_Definition: Skin diseases caused by viruses.
MeSH_Name: Skin Diseases, Viral
NUI: N0000003547
RxNorm_CUI: 1029386
SNOMED_CID: 128937004
Synonym: Viral Skin Diseases
UMLS_CUI: C0162628
code: C7272
imported from: NDF-RT.owl

Oxyurida Infections [Disease/Finding]
type: Class
subclass of: Secernentea Infections [Disease/Finding]
Display_Name: Oxyurida Infections
MeSH_CUI: M0026099
MeSH_DUI: D017194
MeSH_Definition: Infections with nematodes of the order OXYURIDA.
MeSH_Name: Oxyurida Infections
NUI: N0000003548
RxNorm_CUI: 986714
Synonym: Infections, Oxyurida
UMLS_CUI: C0162629
code: C7274
imported from: NDF-RT.owl

Rhabditida Infections [Disease/Finding]
type: Class
subclass of: Secernentea Infections [Disease/Finding]
Display_Name: Rhabditida Infections
MeSH_CUI: M0026101
MeSH_DUI: D017196
MeSH_Definition: Infections with nematodes of the order RHABDITIDA.
MeSH_Name: Rhabditida Infections
NUI: N0000003549
RxNorm_CUI: 1025888
Synonym: Infections, Rhabditida
UMLS_CUI: C0162631
code: C7276
imported from: NDF-RT.owl

Myocardial Ischemia [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
subclass of: Vascular Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Myocardial Ischemia
MeSH_CUI: M0026104
MeSH_DUI: D017202
MeSH_Definition: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
MeSH_Name: Myocardial Ischemia
NUI: N0000003550
RxNorm_CUI: 1022046
SNOMED_CID: 414545008
SNOMED_CID: 414795007
Synonym: Heart Disease, Ischemic
Synonym: Ischemia, Myocardial
Synonym: Ischemic Heart Disease
UMLS_CUI: C0151744
code: C7278
imported from: NDF-RT.owl

Spirurida Infections [Disease/Finding]
type: Class
subclass of: Secernentea Infections [Disease/Finding]
Display_Name: Spirurida Infections
MeSH_CUI: M0026109
MeSH_DUI: D017205
MeSH_Definition: Infections with nematodes of the order SPIRURIDA.
MeSH_Name: Spirurida Infections
NUI: N0000003552
RxNorm_CUI: 1021997
Synonym: Infections, Spirurida
UMLS_CUI: C0162636
code: C7282
imported from: NDF-RT.owl

Enterobiasis [Disease/Finding]
type: Class
subclass of: Oxyuriasis [Disease/Finding]
type: NamedIndividual
Display_Name: Enterobiasis
MeSH_CUI: M0026142
MeSH_DUI: D017229
MeSH_Definition: Infection with nematodes of the genus ENTEROBIUS; E. vermicularis, the pinworm of man, causes a crawling sensation and pruritus. This condition results in scratching the area, occasionally causing scarification.
MeSH_Name: Enterobiasis
NUI: N0000003557
RxNorm_CUI: 1023562
SNOMED_CID: 266162007
SNOMED_CID: 360419005
Synonym: Enterobius vermicularis Infection
Synonym: Infection, Enterobius vermicularis
Synonym: Infection, Oxyuris vermicularis
Synonym: Oxyuris vermicularis Infection
UMLS_CUI: C0086227
code: C7292
imported from: NDF-RT.owl

Skin and Connective Tissue Diseases [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Skin and Connective Tissue Diseases
MeSH_CUI: M0026454
MeSH_DUI: D017437
MeSH_Definition: A collective term for diseases of the skin and its appendages and of connective tissue.
MeSH_Name: Skin and Connective Tissue Diseases
NUI: N0000003573
RxNorm_CUI: 1027511
UMLS_CUI: C0175166
code: C7324
imported from: NDF-RT.owl

Skin Diseases, Papulosquamous [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
Display_Name: Skin Diseases, Papulosquamous
MeSH_CUI: M0026467
MeSH_DUI: D017444
MeSH_Definition: A group of dermatoses with distinct morphologic features. The primary lesion is most commonly a papule, usually erythematous, with a variable degree of scaling on the surface. Plaques form through the coalescing of primary lesions.
MeSH_Name: Skin Diseases, Papulosquamous
NUI: N0000003577
RxNorm_CUI: 1024350
SNOMED_CID: 22585003
Synonym: Papulosquamous Disorders
Synonym: Papulosquamous Skin Diseases
UMLS_CUI: C0162818
code: C7332
imported from: NDF-RT.owl

Skin Diseases, Vascular [Disease/Finding]
type: Class
subclass of: Skin Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Skin Diseases, Vascular
MeSH_CUI: M0026469
MeSH_DUI: D017445
MeSH_Definition: Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area.
MeSH_Name: Skin Diseases, Vascular
NUI: N0000003578
RxNorm_CUI: 1024271
SNOMED_CID: 11263005
Synonym: Vascular Skin Diseases
UMLS_CUI: C0162819
code: C7334
imported from: NDF-RT.owl

Acneiform Eruptions [Disease/Finding]
type: Class
subclass of: Facial Dermatoses [Disease/Finding]
Display_Name: Acneiform Eruptions
MeSH_CUI: M0026528
MeSH_DUI: D017486
MeSH_Definition: Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575)
MeSH_Name: Acneiform Eruptions
NUI: N0000003583
RxNorm_CUI: 1027471
SNOMED_CID: 402644006
UMLS_CUI: C0175167
code: C7344
imported from: NDF-RT.owl

Neuroectodermal Tumors [Disease/Finding]
type: Class
subclass of: Neoplasms, Germ Cell and Embryonal [Disease/Finding]
subclass of: Neoplasms, Nerve Tissue [Disease/Finding]
Display_Name: Neuroectodermal Tumors
MeSH_CUI: M0026668
MeSH_DUI: D017599
MeSH_Definition: Malignant neoplasms arising in the neuroectoderm, the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems, including some glial cells.
MeSH_Name: Neuroectodermal Tumors
NUI: N0000003613
RxNorm_CUI: 1022212
SNOMED_CID: 253096008
SNOMED_CID: 73676002
UMLS_CUI: C0206093
code: C7404
imported from: NDF-RT.owl

Hypereosinophilic Syndrome [Disease/Finding]
type: Class
subclass of: Eosinophilia [Disease/Finding]
type: NamedIndividual
Display_Name: Hypereosinophilic Syndrome
MeSH_CUI: M0026741
MeSH_DUI: D017681
MeSH_Definition: A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.
MeSH_Name: Hypereosinophilic Syndrome
NUI: N0000003620
RxNorm_CUI: 1024984
SNOMED_CID: 128835008
UMLS_CUI: C1540912
code: C7418
imported from: NDF-RT.owl

Flavivirus Infections [Disease/Finding]
type: Class
subclass of: Flaviviridae Infections [Disease/Finding]
Display_Name: Flavivirus Infections
MeSH_CUI: M0027404
MeSH_DUI: D018177
MeSH_Definition: Infections with viruses of the genus FLAVIVIRUS, family FLAVIVIRIDAE.
MeSH_Name: Flavivirus Infections
NUI: N0000003657
RxNorm_CUI: 1027981
Synonym: Infections, Flavivirus
UMLS_CUI: C0206608
code: C7492
imported from: NDF-RT.owl

Flaviviridae Infections [Disease/Finding]
type: Class
subclass of: RNA Virus Infections [Disease/Finding]
Display_Name: Flaviviridae Infections
MeSH_CUI: M0027405
MeSH_DUI: D018178
MeSH_Definition: Infections with viruses of the family FLAVIVIRIDAE.
MeSH_Name: Flaviviridae Infections
NUI: N0000003658
RxNorm_CUI: 1027902
Synonym: Infections, Flaviviridae
UMLS_CUI: C0206609
code: C7494
imported from: NDF-RT.owl

Paramyxoviridae Infections [Disease/Finding]
type: Class
subclass of: Mononegavirales Infections [Disease/Finding]
Display_Name: Paramyxoviridae Infections
MeSH_CUI: M0027412
MeSH_DUI: D018184
MeSH_Definition: Infections with viruses of the family PARAMYXOVIRIDAE. This includes MORBILLIVIRUS INFECTIONS; RESPIROVIRUS INFECTIONS; PNEUMOVIRUS INFECTIONS; HENIPAVIRUS INFECTIONS; AVULAVIRUS INFECTIONS; and RUBULAVIRUS INFECTIONS.
MeSH_Name: Paramyxoviridae Infections
NUI: N0000003660
RxNorm_CUI: 1028342
Synonym: Infections, Paramyxoviridae
UMLS_CUI: C0206613
code: C7498
imported from: NDF-RT.owl

Pneumovirus Infections [Disease/Finding]
type: Class
subclass of: Paramyxoviridae Infections [Disease/Finding]
Display_Name: Pneumovirus Infections
MeSH_CUI: M0027415
MeSH_DUI: D018186
MeSH_Definition: Infections with viruses of the genus PNEUMOVIRUS, family PARAMYXOVIRIDAE. This includes RESPIRATORY SYNCYTIAL VIRUS INFECTIONS, an important cause of respiratory disease in humans.
MeSH_Name: Pneumovirus Infections
NUI: N0000003662
RxNorm_CUI: 1023009
Synonym: Infections, Pneumovirus
UMLS_CUI: C0206615
code: C7502
imported from: NDF-RT.owl

Neoplasms, Connective and Soft Tissue [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Connective and Soft Tissue
MeSH_CUI: M0027433
MeSH_DUI: D018204
MeSH_Definition: Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.
MeSH_Name: Neoplasms, Connective and Soft Tissue
NUI: N0000003678
RxNorm_CUI: 1028165
Synonym: Connective and Soft Tissue Neoplasms
UMLS_CUI: C0206765
code: C7534
imported from: NDF-RT.owl

Neoplasms, Ductal, Lobular, and Medullary [Disease/Finding]
type: Class
subclass of: Neoplasms, Glandular and Epithelial [Disease/Finding]
Display_Name: Neoplasms, Ductal, Lobular, and Medullary
MeSH_CUI: M0027533
MeSH_DUI: D018299
MeSH_Definition: Neoplasms, usually carcinoma, located within the center of an organ or within small lobes, and in the case of the breast, intraductally. The emphasis of the name is on the location of the neoplastic tissue rather than on its histological type. Most cancers of this type are located in the breast.
MeSH_Name: Neoplasms, Ductal, Lobular, and Medullary
NUI: N0000003763
RxNorm_CUI: 1023140
SNOMED_CID: 189704005
Synonym: Ductal, Lobular, and Medullary Neoplasms
UMLS_CUI: C0206768
code: C7704
imported from: NDF-RT.owl

Nevi and Melanomas [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Nevi and Melanomas
MeSH_CUI: M0027561
MeSH_DUI: D018326
MeSH_Definition: A collective term for the various types of nevi and melanomas.
MeSH_Name: Nevi and Melanomas
NUI: N0000003787
RxNorm_CUI: 1027690
SNOMED_CID: 189747005
Synonym: Melanomas and Nevi
UMLS_CUI: C0206769
code: C7752
imported from: NDF-RT.owl

Respiratory Syncytial Virus Infections [Disease/Finding]
type: Class
subclass of: Pneumovirus Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Respiratory Syncytial Virus Infections
MeSH_CUI: M0027589
MeSH_DUI: D018357
MeSH_Definition: Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.
MeSH_Name: Respiratory Syncytial Virus Infections
NUI: N0000003803
RxNorm_CUI: 986730
SNOMED_CID: 55735004
Synonym: Infections, Respiratory Syncytial Virus
UMLS_CUI: C0035235
code: C7784
imported from: NDF-RT.owl

Neuroendocrine Tumors [Disease/Finding]
type: Class
subclass of: Neuroectodermal Tumors [Disease/Finding]
type: NamedIndividual
Display_Name: Neuroendocrine Tumors
MeSH_CUI: M0027590
MeSH_DUI: D018358
MeSH_Definition: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
MeSH_Name: Neuroendocrine Tumors
NUI: N0000003804
RxNorm_CUI: 1024535
SNOMED_CID: 255046005
UMLS_CUI: C0206754
code: C7786
imported from: NDF-RT.owl

Cardiovascular Abnormalities [Disease/Finding]
type: Class
subclass of: Congenital Abnormalities [Disease/Finding]
subclass of: Cardiovascular Diseases [Disease/Finding]
Display_Name: Cardiovascular Abnormalities
MeSH_CUI: M0027602
MeSH_DUI: D018376
MeSH_Definition: Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
MeSH_Name: Cardiovascular Abnormalities
NUI: N0000003808
RxNorm_CUI: 1026475
SNOMED_CID: 9904008
Synonym: Abnormalities, Cardiovascular
UMLS_CUI: C0243050
code: C7794
imported from: NDF-RT.owl

Pneumonia, Bacterial [Disease/Finding]
type: Class
subclass of: Bacterial Infections [Disease/Finding]
subclass of: Pneumonia [Disease/Finding]
Display_Name: Pneumonia, Bacterial
MeSH_CUI: M0027639
MeSH_DUI: D018410
MeSH_Definition: Inflammation of the lung parenchyma that is caused by bacterial infections.
MeSH_Name: Pneumonia, Bacterial
NUI: N0000003812
RxNorm_CUI: 1025309
SNOMED_CID: 53084003
Synonym: Bacterial Pneumonia
UMLS_CUI: C0004626
code: C7802
imported from: NDF-RT.owl

Mononegavirales Infections [Disease/Finding]
type: Class
subclass of: RNA Virus Infections [Disease/Finding]
Display_Name: Mononegavirales Infections
MeSH_CUI: M0028015
MeSH_DUI: D018701
MeSH_Definition: Infections with viruses of the order MONONEGAVIRALES. The concept includes FILOVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; and RHABDOVIRIDAE INFECTIONS.
MeSH_Name: Mononegavirales Infections
NUI: N0000003845
RxNorm_CUI: 1023194
Synonym: Infections, Mononegavirales
UMLS_CUI: C0242916
code: C7868
imported from: NDF-RT.owl

Encephalitis, Viral [Disease/Finding]
type: Class
subclass of: Encephalitis [Disease/Finding]
Display_Name: Encephalitis, Viral
MeSH_CUI: M0028131
MeSH_DUI: D018792
MeSH_Definition: Inflammation of brain parenchymal tissue as a result of viral infection. Encephalitis may occur as primary or secondary manifestation of TOGAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; BUNYAVIRIDAE INFECTIONS; PICORNAVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RETROVIRIDAE INFECTIONS; and ARENAVIRIDAE INFECTIONS.
MeSH_Name: Encephalitis, Viral
NUI: N0000003858
RxNorm_CUI: 1025326
SNOMED_CID: 34476008
Synonym: Encephalomyelitis, Infectious, Viral
Synonym: Infectious Encephalomyelitis, Viral
Synonym: Viral Encephalitis
UMLS_CUI: C0243010
code: C7894
imported from: NDF-RT.owl

Neurodegenerative Diseases [Disease/Finding]
type: Class
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Neurodegenerative Diseases
MeSH_CUI: M0029135
MeSH_DUI: D019636
MeSH_Definition: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
MeSH_Name: Neurodegenerative Diseases
NUI: N0000003949
RxNorm_CUI: 1022112
Synonym: Degenerative Diseases, Nervous System
Synonym: Degenerative Diseases, Neurologic
Synonym: Degenerative Neurologic Diseases
Synonym: Degenerative Neurologic Disorders
Synonym: Nervous System Degenerative Diseases
Synonym: Neurodegenerative Disorders
Synonym: Neurologic Degenerative Conditions
Synonym: Neurologic Degenerative Diseases
Synonym: Neurologic Diseases, Degenerative
UMLS_CUI: C0524851
code: C8076
imported from: NDF-RT.owl

Hepatitis, Autoimmune [Disease/Finding]
type: Class
subclass of: Autoimmune Diseases [Disease/Finding]
subclass of: Hepatitis, Chronic [Disease/Finding]
type: NamedIndividual
Display_Name: Hepatitis, Autoimmune
MeSH_CUI: M0029243
MeSH_DUI: D019693
MeSH_Definition: A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES.
MeSH_Name: Hepatitis, Autoimmune
NUI: N0000003952
RxNorm_CUI: 1021796
SNOMED_CID: 408335007
Synonym: Autoimmune Chronic Hepatitis
Synonym: Autoimmune Hepatitis
UMLS_CUI: C0241910
code: C8082
imported from: NDF-RT.owl

Hepatitis C, Chronic [Disease/Finding]
type: Class
subclass of: Hepatitis, Chronic [Disease/Finding]
subclass of: Hepatitis C [Disease/Finding]
type: NamedIndividual
Display_Name: Hepatitis C, Chronic
MeSH_CUI: M0029252
MeSH_DUI: D019698
MeSH_Definition: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.
MeSH_Name: Hepatitis C, Chronic
NUI: N0000003954
RxNorm_CUI: 1025809
SNOMED_CID: 128302006
Synonym: Chronic Hepatitis C
UMLS_CUI: C0524910
code: C8086
imported from: NDF-RT.owl

Mental Disorders Diagnosed in Childhood [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
Display_Name: Mental Disorders Diagnosed in Childhood
MeSH_CUI: M0029626
MeSH_DUI: D019952
MeSH_Definition: Those psychiatric disorders usually first diagnosed in infancy, childhood, or adolescence. These disorders can also be first diagnosed during other life stages.
MeSH_Name: Mental Disorders Diagnosed in Childhood
NUI: N0000003966
RxNorm_CUI: 987008
Synonym: Disorders Usually Diagnosed in Infancy, Childhood or Adolescence
UMLS_CUI: C0525040
code: C8110
imported from: NDF-RT.owl

Neurobehavioral Manifestations [Disease/Finding]
type: Class
subclass of: Mental Disorders and Manifestations [Disease/Finding]
subclass of: Neurologic Manifestations [Disease/Finding]
Display_Name: Neurobehavioral Manifestations
MeSH_CUI: M0333801
MeSH_DUI: D019954
MeSH_Definition: Signs and symptoms of higher cortical dysfunction caused by organic conditions. These include certain behavioral alterations and impairments of skills involved in the acquisition, processing, and utilization of knowledge or information.
MeSH_Name: Neurobehavioral Manifestations
NUI: N0000003967
RxNorm_CUI: 1025867
Synonym: Cognitive Manifestations
Synonym: Cognitive Symptoms
Synonym: Neurobehavioral Signs and Symptoms
Synonym: Signs and Symptoms, Neurobehavioral
UMLS_CUI: C0525041
code: C8112
imported from: NDF-RT.owl

Attention Deficit and Disruptive Behavior Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders Diagnosed in Childhood [Disease/Finding]
type: NamedIndividual
Display_Name: Attention Deficit and Disruptive Behavior Disorders
MeSH_CUI: M0029636
MeSH_DUI: D019958
MeSH_Name: Attention Deficit and Disruptive Behavior Disorders
NUI: N0000003971
RxNorm_CUI: 1031543
UMLS_CUI: C0236964
code: C8120
imported from: NDF-RT.owl

Mood Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: Mood Disorders
MeSH_CUI: M0029642
MeSH_DUI: D019964
MeSH_Definition: Those disorders that have a disturbance in mood as their predominant feature.
MeSH_Name: Mood Disorders
NUI: N0000003975
RxNorm_CUI: 1022464
SNOMED_CID: 46206005
Synonym: Affective Disorders
UMLS_CUI: C0525045
code: C8128
imported from: NDF-RT.owl

Delirium, Dementia, Amnestic, Cognitive Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
Display_Name: Delirium, Dementia, Amnestic, Cognitive Disorders
MeSH_CUI: M0029645
MeSH_DUI: D019965
MeSH_Definition: Cognitive disorders including delirium, dementia, and other cognitive disorders. These may be the result of substance use, trauma, or other causes.
MeSH_Name: Delirium, Dementia, Amnestic, Cognitive Disorders
NUI: N0000003976
RxNorm_CUI: 1022574
SNOMED_CID: 106014008
SNOMED_CID: 111479008
Synonym: Mental Disorders, Organic
Synonym: Organic Mental Disorders
UMLS_CUI: C0029227
code: C8130
imported from: NDF-RT.owl

Substance-Related Disorders [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
Display_Name: Substance-Related Disorders
MeSH_CUI: M0029657
MeSH_DUI: D019966
MeSH_Definition: Disorders related to substance abuse, the side effects of a medication, or toxin exposure.
MeSH_Name: Substance-Related Disorders
NUI: N0000003977
RxNorm_CUI: 1027904
UMLS_CUI: C0236969
code: C8132
imported from: NDF-RT.owl

Schizophrenia and Disorders with Psychotic Features [Disease/Finding]
type: Class
subclass of: Mental Disorders [Disease/Finding]
Display_Name: Schizophrenia and Disorders with Psychotic Features
MeSH_CUI: M0029660
MeSH_DUI: D019967
MeSH_Definition: Marked disorders of thought (delusions, hallucinations, or other thought disorder accompanied by disordered affect or behavior), and deterioration from a previous level of functioning.
MeSH_Name: Schizophrenia and Disorders with Psychotic Features
NUI: N0000003978
RxNorm_CUI: 984843
UMLS_CUI: C0525046
code: C8134
imported from: NDF-RT.owl

Epstein-Barr Virus Infections [Disease/Finding]
type: Class
subclass of: Herpesviridae Infections [Disease/Finding]
subclass of: Tumor Virus Infections [Disease/Finding]
type: NamedIndividual
Display_Name: Epstein-Barr Virus Infections
MeSH_CUI: M0029738
MeSH_DUI: D020031
MeSH_Definition: Infection with human herpesvirus 4 (HERPESVIRUS 4, HUMAN); which may facilitate the development of various lymphoproliferative disorders. These include BURKITT LYMPHOMA (African type), INFECTIOUS MONONUCLEOSIS, and oral hairy leukoplakia (LEUKOPLAKIA, HAIRY).
MeSH_Name: Epstein-Barr Virus Infections
NUI: N0000003987
RxNorm_CUI: 1024384
SNOMED_CID: 402121009
Synonym: EBV Infections
Synonym: Herpesvirus 4 Infections, Human
Synonym: Human Herpes Virus 4 Infections
Synonym: Human Herpesvirus 4 Infections
Synonym: Infections, EBV
Synonym: Infections, Epstein-Barr Virus
UMLS_CUI: C0149678
code: C8152
imported from: NDF-RT.owl

Hemostatic Disorders [Disease/Finding]
type: Class
subclass of: Hemorrhagic Disorders [Disease/Finding]
subclass of: Vascular Diseases [Disease/Finding]
Display_Name: Hemostatic Disorders
MeSH_CUI: M0029879
MeSH_DUI: D020141
MeSH_Definition: Pathological processes involving the integrity of blood circulation. Hemostasis depends on the integrity of BLOOD VESSELS, blood fluidity, and BLOOD COAGULATION. Majority of the hemostatic disorders are caused by disruption of the normal interaction between the VASCULAR ENDOTHELIUM, the plasma proteins (including BLOOD COAGULATION FACTORS), and PLATELETS.
MeSH_Name: Hemostatic Disorders
NUI: N0000003999
RxNorm_CUI: 1023569
SNOMED_CID: 21112004
Synonym: Hemostatic Disorders, Vascular
Synonym: Vascular Hemostatic Disorders
UMLS_CUI: C0600502
code: C8176
imported from: NDF-RT.owl

Venous Thrombosis [Disease/Finding]
type: Class
subclass of: Thrombosis [Disease/Finding]
type: NamedIndividual
Display_Name: Venous Thrombosis
MeSH_CUI: M0029908
MeSH_DUI: D020246
MeSH_Definition: The formation or presence of a blood clot (THROMBUS) within a vein.
MeSH_Name: Venous Thrombosis
NUI: N0000004074
RxNorm_CUI: 1023173
SNOMED_CID: 111293003
SNOMED_CID: 18266009
Synonym: Phlebothrombosis
Synonym: Thrombosis, Venous
UMLS_CUI: C0042487
code: C8326
imported from: NDF-RT.owl

Autoimmune Diseases of the Nervous System [Disease/Finding]
type: Class
subclass of: Autoimmune Diseases [Disease/Finding]
subclass of: Nervous System Diseases [Disease/Finding]
Display_Name: Autoimmune Diseases of the Nervous System
MeSH_CUI: M0328129
MeSH_DUI: D020274
MeSH_Definition: Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).
MeSH_Name: Autoimmune Diseases of the Nervous System
NUI: N0000004092
RxNorm_CUI: 1025977
Synonym: Autoimmune Diseases, Nervous System
Synonym: Autoimmune Diseases, Neurologic
Synonym: Autoimmune Disorders of the Nervous System
Synonym: Autoimmune Disorders, Nervous System
Synonym: Autoimmune Nervous System Diseases
Synonym: Nervous System Autoimmune Diseases
Synonym: Neurologic Autoimmune Diseases
UMLS_CUI: C0751871
code: C8362
imported from: NDF-RT.owl

Demyelinating Autoimmune Diseases, CNS [Disease/Finding]
type: Class
subclass of: Demyelinating Diseases [Disease/Finding]
subclass of: Autoimmune Diseases of the Nervous System [Disease/Finding]
subclass of: Leukoencephalopathies [Disease/Finding]
Display_Name: Demyelinating Autoimmune Diseases, CNS
MeSH_CUI: M0328372
MeSH_DUI: D020278
MeSH_Definition: Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.
MeSH_Name: Demyelinating Autoimmune Diseases, CNS
NUI: N0000004095
RxNorm_CUI: 989466
Synonym: Autoimmune Demyelinating Diseases, CNS
Synonym: Autoimmune Demyelinating Diseases, Central Nervous System
Synonym: Autoimmune Demyelinating Disorders, CNS
Synonym: CNS Autoimmune Demyelinating Disorders
Synonym: CNS Demyelinating Autoimmune Diseases
Synonym: Demyelinating Autoimmune Diseases, Central Nervous System
Synonym: Demyelinating Autoimmune Disorders, CNS
Synonym: Demyelinating Disease, Autoimmune, CNS
UMLS_CUI: C0751873
code: C8368
imported from: NDF-RT.owl

Intracranial Hemorrhages [Disease/Finding]
type: Class
subclass of: Cerebrovascular Disorders [Disease/Finding]
subclass of: Hemorrhage [Disease/Finding]
type: NamedIndividual
Display_Name: Intracranial Hemorrhages
MeSH_CUI: M0328611
MeSH_DUI: D020300
MeSH_Definition: Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
MeSH_Name: Intracranial Hemorrhages
NUI: N0000004102
RxNorm_CUI: 1026294
SNOMED_CID: 1386000
Synonym: Hemorrhage, Intracranial
UMLS_CUI: C0151699
code: C8382
imported from: NDF-RT.owl

Neuromuscular Junction Diseases [Disease/Finding]
type: Class
subclass of: Neuromuscular Diseases [Disease/Finding]
Display_Name: Neuromuscular Junction Diseases
MeSH_CUI: M0328288
MeSH_DUI: D020511
MeSH_Definition: Conditions characterized by impaired transmission of impulses at the NEUROMUSCULAR JUNCTION. This may result from disorders that affect receptor function, pre- or postsynaptic membrane function, or ACETYLCHOLINESTERASE activity. The majority of diseases in this category are associated with autoimmune, toxic, or inherited conditions.
MeSH_Name: Neuromuscular Junction Diseases
NUI: N0000004153
RxNorm_CUI: 984412
SNOMED_CID: 128213006
Synonym: Neuromuscular Junction Disorders
Synonym: Neuromuscular Transmission Disorders
UMLS_CUI: C0751950
code: C8484
imported from: NDF-RT.owl

Parkinsonian Disorders [Disease/Finding]
type: Class
subclass of: Basal Ganglia Diseases [Disease/Finding]
subclass of: Movement Disorders [Disease/Finding]
Display_Name: Parkinsonian Disorders
MeSH_CUI: M0328250
MeSH_DUI: D020734
MeSH_Definition: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
MeSH_Name: Parkinsonian Disorders
NUI: N0000004168
RxNorm_CUI: 987649
SNOMED_CID: 32798002
Synonym: Parkinsonian Diseases
Synonym: Parkinsonian Syndrome
Synonym: Parkinsonian Syndromes
Synonym: Parkinsonism
UMLS_CUI: C0242422
code: C8514
imported from: NDF-RT.owl

Brain Diseases, Metabolic, Inborn [Disease/Finding]
type: Class
subclass of: Brain Diseases, Metabolic [Disease/Finding]
subclass of: Metabolism, Inborn Errors [Disease/Finding]
Display_Name: Brain Diseases, Metabolic, Inborn
MeSH_CUI: M0328165
MeSH_DUI: D020739
MeSH_Definition: Brain disorders resulting from inborn metabolic errors, primarily from enzymatic defects which lead to substrate accumulation, product reduction, or increase in toxic metabolites through alternate pathways. The majority of these conditions are familial, however spontaneous mutation may also occur in utero.
MeSH_Name: Brain Diseases, Metabolic, Inborn
NUI: N0000004169
RxNorm_CUI: 1022797
Synonym: Brain Syndrome, Metabolic, Inborn
Synonym: Encephalopathies, Metabolic, Inborn
Synonym: Inborn Errors of Metabolism, Brain
Synonym: Inborn Metabolic Brain Diseases
Synonym: Inborn Metabolic Brain Disorders
Synonym: Inborn Metabolic Disorders, Brain
Synonym: Metabolic Brain Diseases, Inborn
Synonym: Metabolic Brain Syndrome, Inborn
Synonym: Metabolic Diseases, Inborn, Brain
UMLS_CUI: C0752109
code: C8516
imported from: NDF-RT.owl

Central Nervous System Viral Diseases [Disease/Finding]
type: Class
subclass of: Central Nervous System Infections [Disease/Finding]
subclass of: DOID 934
Display_Name: Central Nervous System Viral Diseases
MeSH_CUI: M0328064
MeSH_DUI: D020805
MeSH_Definition: Viral infections of the brain, spinal cord, meninges, or perimeningeal spaces.
MeSH_Name: Central Nervous System Viral Diseases
NUI: N0000004195
RxNorm_CUI: 1025144
SNOMED_CID: 302810003
Synonym: Central Nervous System Viral Infections
Synonym: Infections, CNS, Viral
Synonym: Infections, Viral CNS
Synonym: Viral Diseases, Central Nervous System
Synonym: Viral Infections, Central Nervous System
UMLS_CUI: C0348165
code: C8568
imported from: NDF-RT.owl

Dyskinesias [Disease/Finding]
type: Class
subclass of: Movement Disorders [Disease/Finding]
subclass of: Neurologic Manifestations [Disease/Finding]
type: NamedIndividual
Display_Name: Dyskinesias
MeSH_CUI: M0014140
MeSH_DUI: D020820
MeSH_Definition: Abnormal involuntary movements which primarily affect the extremities, trunk, or jaw that occur as a manifestation of an underlying disease process. Conditions which feature recurrent or persistent episodes of dyskinesia as a primary manifestation of disease may be referred to as dyskinesia syndromes (see MOVEMENT DISORDERS). Dyskinesias are also a relatively common manifestation of BASAL GANGLIA DISEASES.
MeSH_Name: Dyskinesias
NUI: N0000004204
RxNorm_CUI: 1021897
SNOMED_CID: 9748009
Synonym: Abnormal Movements
UMLS_CUI: C0013384
code: C8586
imported from: NDF-RT.owl

Urological Manifestations [Disease/Finding]
type: Class
subclass of: Signs and Symptoms [Disease/Finding]
Display_Name: Urological Manifestations
MeSH_CUI: M0328644
MeSH_DUI: D020924
MeSH_Definition: Clinical disturbances of the urinary system.
MeSH_Name: Urological Manifestations
NUI: N0000004224
RxNorm_CUI: 988624
UMLS_CUI: C0752303
code: C8626
imported from: NDF-RT.owl

Carcinoma, Pancreatic Ductal [Disease/Finding]
type: Class
subclass of: Pancreatic Neoplasms [Disease/Finding]
subclass of: Carcinoma, Ductal [Disease/Finding]
Display_Name: Carcinoma, Pancreatic Ductal
MeSH_CUI: M0352972
MeSH_DUI: D021441
MeSH_Definition: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
MeSH_Name: Carcinoma, Pancreatic Ductal
NUI: N0000004241
RxNorm_CUI: 985550
Synonym: Carcinoma, Ductal, Pancreatic
Synonym: Duct-Cell Carcinoma of the Pancreas
Synonym: Duct-Cell Carcinoma, Pancreas
Synonym: Ductal Carcinoma of the Pancreas
Synonym: Pancreatic Duct Cell Carcinoma
Synonym: Pancreatic Ductal Carcinoma
UMLS_CUI: C0887833
code: C8660
imported from: NDF-RT.owl

mycophenolate mofetil [Chemical/Ingredient]
type: Class
subclass of: Mycophenolic Acid [Chemical/Ingredient]
Display_Name: mycophenolate mofetil
MeSH_CUI: M0174120
MeSH_DUI: C063008
MeSH_Name: mycophenolate mofetil
NUI: N0000005137
RxNorm_CUI: 68149
RxNorm_Name: mycophenolate mofetil
Synonym: mycophenolic acid morpholinoethyl ester
UMLS_CUI: C0209368
code: C17504
imported from: NDF-RT.owl

Methylprednisolone [Chemical/Ingredient]
type: Class
subclass of: Prednisolone [Chemical/Ingredient]
Display_Name: Methylprednisolone
MeSH_CUI: M0013662
MeSH_DUI: D008775
MeSH_Definition: A PREDNISOLONE derivative with similar anti-inflammatory action.
MeSH_Name: Methylprednisolone
NUI: N0000005719
RxNorm_CUI: 6902
RxNorm_Name: Methylprednisolone
Synonym: 6-Methylprednisolone
Synonym: Metipred
Synonym: Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6alpha,11beta)-
UMLS_CUI: C0025815
code: C21782
imported from: NDF-RT.owl

Carbohydrates [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Carbohydrates
MeSH_CUI: M0003360
MeSH_DUI: D002241
MeSH_Definition: The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.
MeSH_Name: Carbohydrates
NUI: N0000005723
RxNorm_CUI: 2028
UMLS_CUI: C0007004
code: C21790
imported from: NDF-RT.owl

Amiodarone [Chemical/Ingredient]
type: Class
subclass of: Benzofurans [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Amiodarone
MeSH_CUI: M0000973
MeSH_DUI: D000638
MeSH_Definition: An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance.
MeSH_Name: Amiodarone
NUI: N0000005761
RxNorm_CUI: 703
RxNorm_Name: Amiodarone
Synonym: Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-
UMLS_CUI: C0002598
code: C21866
imported from: NDF-RT.owl

Proteins [Chemical/Ingredient]
type: Class
subclass of: Amino Acids, Peptides, and Proteins [Chemical/Ingredient]
Display_Name: Proteins
MeSH_CUI: M0017890
MeSH_DUI: D011506
MeSH_Definition: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
MeSH_Name: Proteins
NUI: N0000005817
RxNorm_CUI: 8859
RxNorm_Name: Proteins
UMLS_CUI: C0033684
code: C21978
imported from: NDF-RT.owl

Amodiaquine [Chemical/Ingredient]
type: Class
subclass of: Aminoquinolines [Chemical/Ingredient]
Display_Name: Amodiaquine
MeSH_CUI: M0001005
MeSH_DUI: D000655
MeSH_Definition: A 4-aminoquinoline compound with anti-inflammatory properties.
MeSH_Name: Amodiaquine
NUI: N0000005832
RxNorm_CUI: 720
RxNorm_Name: Amodiaquine
Synonym: Amodiachin
Synonym: Amodiaquin
Synonym: Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-
UMLS_CUI: C0002641
code: C22008
imported from: NDF-RT.owl

Simvastatin [Chemical/Ingredient]
type: Class
subclass of: Lovastatin [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Simvastatin
MeSH_CUI: M0029425
MeSH_DUI: D019821
MeSH_Definition: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
MeSH_Name: Simvastatin
NUI: N0000005842
RxNorm_CUI: 36567
RxNorm_Name: Simvastatin
Synonym: Synvinolin
UMLS_CUI: C0074554
code: C22028
imported from: NDF-RT.owl

Phenazopyridine [Chemical/Ingredient]
type: Class
subclass of: Aminopyridines [Chemical/Ingredient]
Display_Name: Phenazopyridine
MeSH_CUI: M0016493
MeSH_DUI: D010621
MeSH_Definition: A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
MeSH_Name: Phenazopyridine
NUI: N0000005854
RxNorm_CUI: 8120
RxNorm_Name: Phenazopyridine
Synonym: 2,6-Pyridinediamine, 3-(phenylazo)-
UMLS_CUI: C0031379
code: C22052
imported from: NDF-RT.owl

Ribavirin [Chemical/Ingredient]
type: Class
subclass of: Ribonucleosides [Chemical/Ingredient]
Display_Name: Ribavirin
MeSH_CUI: M0019062
MeSH_DUI: D012254
MeSH_Definition: A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.
MeSH_Name: Ribavirin
NUI: N0000005892
RxNorm_CUI: 9344
RxNorm_Name: Ribavirin
Synonym: 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-
Synonym: Ribovirin
Synonym: Tribavirin
UMLS_CUI: C0035525
code: C22128
imported from: NDF-RT.owl

Digitoxin [Chemical/Ingredient]
type: Class
subclass of: Digitalis Glycosides [Chemical/Ingredient]
Display_Name: Digitoxin
MeSH_CUI: M0006383
MeSH_DUI: D004074
MeSH_Definition: A cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
MeSH_Name: Digitoxin
NUI: N0000005895
RxNorm_CUI: 3403
RxNorm_Name: Digitoxin
Synonym: Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-14-hydroxy-, (3beta,5beta)-
UMLS_CUI: C0012258
code: C22134
imported from: NDF-RT.owl

Digoxin [Chemical/Ingredient]
type: Class
subclass of: Digitalis Glycosides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Digoxin
MeSH_CUI: M0006386
MeSH_DUI: D004077
MeSH_Definition: A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
MeSH_Name: Digoxin
NUI: N0000005903
RxNorm_CUI: 3407
RxNorm_Name: Digoxin
Synonym: Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
UMLS_CUI: C0012265
code: C22150
imported from: NDF-RT.owl

Progesterone [Chemical/Ingredient]
type: Class
subclass of: Pregnenediones [Chemical/Ingredient]
subclass of: Corpus Luteum Hormones [Chemical/Ingredient]
subclass of: Progesterone Congeners [Chemical/Ingredient]
Display_Name: Progesterone
MeSH_CUI: M0017672
MeSH_DUI: D011374
MeSH_Definition: The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
MeSH_Name: Progesterone
NUI: N0000005934
RxNorm_CUI: 8727
RxNorm_Name: Progesterone
Synonym: Pregn-4-ene-3,20-dione
Synonym: Pregnenedione
UMLS_CUI: C0033308
code: C22212
imported from: NDF-RT.owl

Dihydroergotamine [Chemical/Ingredient]
type: Class
subclass of: Ergotamines [Chemical/Ingredient]
Display_Name: Dihydroergotamine
MeSH_CUI: M0006401
MeSH_DUI: D004087
MeSH_Definition: A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of MIGRAINE DISORDERS.
MeSH_Name: Dihydroergotamine
NUI: N0000005941
RxNorm_CUI: 3418
RxNorm_Name: Dihydroergotamine
Synonym: Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,10alpha)-
UMLS_CUI: C0012291
code: C22226
imported from: NDF-RT.owl

Triazolam [Chemical/Ingredient]
type: Class
subclass of: Benzodiazepines [Chemical/Ingredient]
Display_Name: Triazolam
MeSH_CUI: M0021910
MeSH_DUI: D014229
MeSH_Definition: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.
MeSH_Name: Triazolam
NUI: N0000006001
RxNorm_CUI: 10767
RxNorm_Name: Triazolam
Synonym: 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-(2-chlorophenyl)-1-methyl-
UMLS_CUI: C0040879
code: C22346
imported from: NDF-RT.owl

Promethazine [Chemical/Ingredient]
type: Class
subclass of: Phenothiazines [Chemical/Ingredient]
subclass of: Propylamines [Chemical/Ingredient]
Display_Name: Promethazine
MeSH_CUI: M0017706
MeSH_DUI: D011398
MeSH_Definition: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
MeSH_Name: Promethazine
NUI: N0000006007
RxNorm_CUI: 8745
RxNorm_Name: Promethazine
Synonym: 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-
Synonym: Proazamine
Synonym: Prometazin
UMLS_CUI: C0033405
code: C22358
imported from: NDF-RT.owl

6-Mercaptopurine [Chemical/Ingredient]
type: Class
subclass of: Sulfhydryl Compounds [Chemical/Ingredient]
subclass of: Purines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: 6-Mercaptopurine
MeSH_CUI: M0023263
MeSH_DUI: D015122
MeSH_Definition: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
MeSH_Name: 6-Mercaptopurine
NUI: N0000006010
RxNorm_CUI: 103
RxNorm_Name: mercaptopurine
Synonym: 1,7-Dihydro-6H-purine-6-thione
Synonym: 6-Thiohypoxanthine
Synonym: 6-Thiopurine
Synonym: 6H-Purine-6-thione, 1,7-dihydro-
Synonym: Mercaptopurine
UMLS_CUI: C0000618
code: C22364
imported from: NDF-RT.owl

Rimantadine [Chemical/Ingredient]
type: Class
subclass of: Adamantane [Chemical/Ingredient]
Display_Name: Rimantadine
MeSH_CUI: M0019119
MeSH_DUI: D012299
MeSH_Definition: An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
MeSH_Name: Rimantadine
NUI: N0000006040
RxNorm_CUI: 9386
RxNorm_Name: Rimantadine
Synonym: Remantadine
Synonym: Riamantadine
Synonym: Tricyclo(3.3.1.13,7)decane-1-methanamine, alpha-methyl-
UMLS_CUI: C0035629
code: C22424
imported from: NDF-RT.owl

Nelfinavir [Chemical/Ingredient]
type: Class
subclass of: Isoquinolines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Nelfinavir
MeSH_CUI: M0029531
MeSH_DUI: D019888
MeSH_Definition: A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
MeSH_Name: Nelfinavir
NUI: N0000006047
RxNorm_CUI: 134527
RxNorm_Name: Nelfinavir
UMLS_CUI: C0525005
code: C22438
imported from: NDF-RT.owl

Pimozide [Chemical/Ingredient]
type: Class
subclass of: Benzimidazoles [Chemical/Ingredient]
Display_Name: Pimozide
MeSH_CUI: M0016871
MeSH_DUI: D010868
MeSH_Definition: A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
MeSH_Name: Pimozide
NUI: N0000006115
RxNorm_CUI: 8331
RxNorm_Name: Pimozide
Synonym: 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
UMLS_CUI: C0031935
code: C22574
imported from: NDF-RT.owl

Triflupromazine [Chemical/Ingredient]
type: Class
subclass of: Phenothiazines [Chemical/Ingredient]
Display_Name: Triflupromazine
MeSH_CUI: M0021962
MeSH_DUI: D014273
MeSH_Definition: A phenothiazine used as an antipsychotic agent and as an antiemetic.
MeSH_Name: Triflupromazine
NUI: N0000006126
RxNorm_CUI: 10805
RxNorm_Name: Triflupromazine
Synonym: 10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-
Synonym: Fluopromazine
Synonym: Trifluopromazine
UMLS_CUI: C0040989
code: C22596
imported from: NDF-RT.owl

Emetine [Chemical/Ingredient]
type: Class
subclass of: Alkaloids [Chemical/Ingredient]
subclass of: Isoquinolines [Chemical/Ingredient]
Display_Name: Emetine
MeSH_CUI: M0007281
MeSH_DUI: D004640
MeSH_Definition: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
MeSH_Name: Emetine
NUI: N0000006145
RxNorm_CUI: 3820
RxNorm_Name: Emetine
Synonym: Emetan, 6',7',10,11-tetramethoxy-
Synonym: Ipecine
Synonym: Methylcephaeline
UMLS_CUI: C0013974
code: C22634
imported from: NDF-RT.owl

Lipids [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
Display_Name: Lipids
MeSH_CUI: M0012553
MeSH_DUI: D008055
MeSH_Definition: A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Lipids
NUI: N0000006185
RxNorm_CUI: 6411
UMLS_CUI: C0023779
code: C22714
imported from: NDF-RT.owl

interferon beta-1b [Chemical/Ingredient]
type: Class
subclass of: Interferon-beta [Chemical/Ingredient]
Display_Name: interferon beta-1b
MeSH_CUI: M0129586
MeSH_DUI: C044327
MeSH_Name: interferon beta-1b
NUI: N0000006215
RxNorm_CUI: 72257
RxNorm_Name: interferon beta-1b
Synonym: IFN-beta ser
Synonym: Ser(17) IFN-beta
Synonym: beta-IFN-1b
Synonym: interferon beta, Ser(17)-
Synonym: interferon beta, serine(17)-
Synonym: serine(17) interferon beta
UMLS_CUI: C0244713
code: C22776
imported from: NDF-RT.owl

Toremifene [Chemical/Ingredient]
type: Class
subclass of: Tamoxifen [Chemical/Ingredient]
Display_Name: Toremifene
MeSH_CUI: M0026287
MeSH_DUI: D017312
MeSH_Definition: A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.
MeSH_Name: Toremifene
NUI: N0000006270
RxNorm_CUI: 38409
RxNorm_Name: Toremifene
Synonym: Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
UMLS_CUI: C0076836
code: C22886
imported from: NDF-RT.owl

Interferon Alfa-2a [Chemical/Ingredient]
type: Class
subclass of: Interferon-alpha [Chemical/Ingredient]
subclass of: Interferon Type I, Recombinant [Chemical/Ingredient]
Display_Name: Interferon Alfa-2a
MeSH_CUI: M0023693
MeSH_DUI: D015380
MeSH_Definition: A recombinant alfa interferon consisting of 165 amino acids with lysine at position 23 and histidine at position 34. It is used extensively as an antiviral and antineoplastic agent.
MeSH_Name: Interferon Alfa-2a
NUI: N0000006291
RxNorm_CUI: 5879
RxNorm_Name: Interferon Alfa-2a
Synonym: Recombinant Interferon Alfa-2a
Synonym: Recombinant Interferon alpha-2a
UMLS_CUI: C0021734
code: C22928
imported from: NDF-RT.owl

Ergotamine [Chemical/Ingredient]
type: Class
subclass of: Ergotamines [Chemical/Ingredient]
Display_Name: Ergotamine
MeSH_CUI: M0007662
MeSH_DUI: D004878
MeSH_Definition: A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS.
MeSH_Name: Ergotamine
NUI: N0000006354
RxNorm_CUI: 4025
RxNorm_Name: Ergotamine
Synonym: Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-
UMLS_CUI: C0014710
code: C23056
imported from: NDF-RT.owl

Ivermectin [Chemical/Ingredient]
type: Class
subclass of: Macrolides [Chemical/Ingredient]
Display_Name: Ivermectin
MeSH_CUI: M0011815
MeSH_DUI: D007559
MeSH_Definition: A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
MeSH_Name: Ivermectin
NUI: N0000006374
RxNorm_CUI: 6069
RxNorm_Name: Ivermectin
UMLS_CUI: C0022322
code: C23096
imported from: NDF-RT.owl

famciclovir [Chemical/Ingredient]
type: Class
subclass of: 2-Aminopurine [Chemical/Ingredient]
Display_Name: famciclovir
MeSH_CUI: M0168276
MeSH_DUI: C060590
MeSH_Name: famciclovir
NUI: N0000006388
RxNorm_CUI: 68099
RxNorm_Name: famciclovir
Synonym: 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine
UMLS_CUI: C0209227
code: C23124
imported from: NDF-RT.owl

Warfarin [Chemical/Ingredient]
type: Class
subclass of: 4-Hydroxycoumarins [Chemical/Ingredient]
Display_Name: Warfarin
MeSH_CUI: M0022871
MeSH_DUI: D014859
MeSH_Definition: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
MeSH_Name: Warfarin
NUI: N0000006403
RxNorm_CUI: 11289
RxNorm_Name: Warfarin
Synonym: 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-
Synonym: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
UMLS_CUI: C0043031
code: C23154
imported from: NDF-RT.owl

Bepridil [Chemical/Ingredient]
type: Class
subclass of: Pyrrolidines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Bepridil
MeSH_CUI: M0024153
MeSH_DUI: D015764
MeSH_Definition: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
MeSH_Name: Bepridil
NUI: N0000006461
RxNorm_CUI: 1436
RxNorm_Name: Bepridil
Synonym: 1-Pyrrolidineethanamine, beta-((2-methylpropoxy)methyl)-N-phenyl-N-(phenylmethyl)-
UMLS_CUI: C0005116
code: C23270
imported from: NDF-RT.owl

Mefloquine [Chemical/Ingredient]
type: Class
subclass of: Quinolines [Chemical/Ingredient]
Display_Name: Mefloquine
MeSH_CUI: M0024162
MeSH_DUI: D015767
MeSH_Definition: A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects.
MeSH_Name: Mefloquine
NUI: N0000006467
RxNorm_CUI: 6694
RxNorm_Name: Mefloquine
Synonym: 4-Quinolinemethanol, alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-, (R*,S*)-(+-)-
Synonym: Mephloquine
UMLS_CUI: C0025153
code: C23282
imported from: NDF-RT.owl

Niclosamide [Chemical/Ingredient]
type: Class
subclass of: Salicylanilides [Chemical/Ingredient]
Display_Name: Niclosamide
MeSH_CUI: M0014827
MeSH_DUI: D009534
MeSH_Definition: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
MeSH_Name: Niclosamide
NUI: N0000006489
RxNorm_CUI: 7402
RxNorm_Name: Niclosamide
Synonym: Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-
UMLS_CUI: C0028017
code: C23326
imported from: NDF-RT.owl

gemcitabine [Chemical/Ingredient]
type: Class
subclass of: Deoxycytidine [Chemical/Ingredient]
Display_Name: gemcitabine
MeSH_CUI: M0158478
MeSH_DUI: C056507
MeSH_Name: gemcitabine
NUI: N0000006563
RxNorm_CUI: 12574
RxNorm_Name: gemcitabine
Synonym: 2',2'-DFDC
Synonym: 2',2'-difluoro-2'-deoxycytidine
Synonym: 2',2'-difluorodeoxycytidine
Synonym: 2'-deoxy-2'-difluorocytidine
Synonym: dFdCyd
UMLS_CUI: C0045093
code: C23474
imported from: NDF-RT.owl

Hydroxychloroquine [Chemical/Ingredient]
type: Class
subclass of: Chloroquine [Chemical/Ingredient]
Display_Name: Hydroxychloroquine
MeSH_CUI: M0010751
MeSH_DUI: D006886
MeSH_Definition: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
MeSH_Name: Hydroxychloroquine
NUI: N0000006573
RxNorm_CUI: 5521
RxNorm_Name: Hydroxychloroquine
Synonym: Hydroxychlorochin
Synonym: Oxychlorochin
Synonym: Oxychloroquine
Synonym: ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-
UMLS_CUI: C0020336
code: C23494
imported from: NDF-RT.owl

Cisapride [Chemical/Ingredient]
type: Class
subclass of: Benzamides [Chemical/Ingredient]
subclass of: Piperidines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cisapride
MeSH_CUI: M0029858
MeSH_DUI: D020117
MeSH_Definition: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
MeSH_Name: Cisapride
NUI: N0000006590
RxNorm_CUI: 35255
RxNorm_Name: Cisapride
Synonym: Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy -4-piperidinyl)-2-methoxy-, cis-
UMLS_CUI: C0072916
code: C23528
imported from: NDF-RT.owl

terconazole [Chemical/Ingredient]
type: Class
subclass of: Triazoles [Chemical/Ingredient]
Display_Name: terconazole
MeSH_CUI: M0114183
MeSH_DUI: C037815
MeSH_Name: terconazole
NUI: N0000006622
RxNorm_CUI: 37806
RxNorm_Name: terconazole
Synonym: 1-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-(1-methylethyl)piperazine
UMLS_CUI: C0076115
code: C23592
imported from: NDF-RT.owl

Reserpine [Chemical/Ingredient]
type: Class
subclass of: Yohimbine [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Reserpine
MeSH_CUI: M0018861
MeSH_DUI: D012110
MeSH_Definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
MeSH_Name: Reserpine
NUI: N0000006632
RxNorm_CUI: 9260
RxNorm_Name: Reserpine
Synonym: Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
UMLS_CUI: C0035179
code: C23612
imported from: NDF-RT.owl

Prednisolone [Chemical/Ingredient]
type: Class
subclass of: Pregnadienetriols [Chemical/Ingredient]
Display_Name: Prednisolone
MeSH_CUI: M0017460
MeSH_DUI: D011239
MeSH_Definition: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
MeSH_Name: Prednisolone
NUI: N0000006669
RxNorm_CUI: 8638
RxNorm_Name: prednisolone
Synonym: Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-
UMLS_CUI: C0032950
code: C23686
imported from: NDF-RT.owl

Propafenone [Chemical/Ingredient]
type: Class
subclass of: Propiophenones [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Propafenone
MeSH_CUI: M0017736
MeSH_DUI: D011405
MeSH_Definition: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
MeSH_Name: Propafenone
NUI: N0000006692
RxNorm_CUI: 8754
RxNorm_Name: Propafenone
Synonym: 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-
UMLS_CUI: C0033429
code: C23732
imported from: NDF-RT.owl

Midazolam [Chemical/Ingredient]
type: Class
subclass of: Benzodiazepines [Chemical/Ingredient]
Display_Name: Midazolam
MeSH_CUI: M0013843
MeSH_DUI: D008874
MeSH_Definition: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
MeSH_Name: Midazolam
NUI: N0000006704
RxNorm_CUI: 6960
RxNorm_Name: Midazolam
Synonym: 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-
UMLS_CUI: C0026056
code: C23756
imported from: NDF-RT.owl

Interferon-alpha [Chemical/Ingredient]
type: Class
subclass of: Interferon Type I [Chemical/Ingredient]
Display_Name: Interferon-alpha
MeSH_CUI: M0025711
MeSH_DUI: D016898
MeSH_Definition: One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
MeSH_Name: Interferon-alpha
NUI: N0000006710
RxNorm_CUI: 541
RxNorm_Name: Interferon-alpha
Synonym: Interferon Alfa
Synonym: Interferon, Leukocyte
Synonym: Interferon, Lymphoblast
Synonym: Interferon, Lymphoblastoid
Synonym: Interferon, alpha
Synonym: alpha-Interferon
UMLS_CUI: C0002199
code: C23768
imported from: NDF-RT.owl

Azithromycin [Chemical/Ingredient]
type: Class
subclass of: Erythromycin [Chemical/Ingredient]
Display_Name: Azithromycin
MeSH_CUI: M0027129
MeSH_DUI: D017963
MeSH_Definition: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
MeSH_Name: Azithromycin
NUI: N0000006752
RxNorm_CUI: 18631
RxNorm_Name: Azithromycin
Synonym: 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, (2R-(2R*,3S*,4R*,5R*,8R
Synonym: Azythromycin
UMLS_CUI: C0052796
code: C23854
imported from: NDF-RT.owl

Yohimbine [Chemical/Ingredient]
type: Class
subclass of: Secologanin Tryptamine Alkaloids [Chemical/Ingredient]
Display_Name: Yohimbine
MeSH_CUI: M0023104
MeSH_DUI: D015016
MeSH_Definition: A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic in the treatment of ERECTILE DYSFUNCTION.
MeSH_Name: Yohimbine
NUI: N0000006817
RxNorm_CUI: 220982
RxNorm_Name: Yohimbe Preparation
Synonym: Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)-
UMLS_CUI: C0724441
code: C23984
imported from: NDF-RT.owl

Fatty Acids [Chemical/Ingredient]
type: Class
subclass of: Lipids [Chemical/Ingredient]
Display_Name: Fatty Acids
MeSH_CUI: M0008265
MeSH_DUI: D005227
MeSH_Definition: Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Fatty Acids
NUI: N0000006847
RxNorm_CUI: 4297
UMLS_CUI: C0015684
code: C24044
imported from: NDF-RT.owl

Chlorpromazine [Chemical/Ingredient]
type: Class
subclass of: Phenothiazines [Chemical/Ingredient]
Display_Name: Chlorpromazine
MeSH_CUI: M0004198
MeSH_DUI: D002746
MeSH_Definition: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
MeSH_Name: Chlorpromazine
NUI: N0000006947
RxNorm_CUI: 2403
RxNorm_Name: Chlorpromazine
Synonym: 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-
UMLS_CUI: C0008286
code: C24244
imported from: NDF-RT.owl

Flecainide [Chemical/Ingredient]
type: Class
subclass of: Piperidines [Chemical/Ingredient]
Display_Name: Flecainide
MeSH_CUI: M0008556
MeSH_DUI: D005424
MeSH_Definition: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial arrhythmias and tachycardias. Paradoxically, however, in myocardial infarct patients with either symptomatic or asymptomatic arrhythmia, flecainide exacerbates the arrhythmia and is not recommended for use in these patients.
MeSH_Name: Flecainide
NUI: N0000006966
RxNorm_CUI: 4441
RxNorm_Name: Flecainide
Synonym: Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-
UMLS_CUI: C0016229
code: C24282
imported from: NDF-RT.owl

Cetylpyridinium [Chemical/Ingredient]
type: Class
subclass of: Pyridinium Compounds [Chemical/Ingredient]
Display_Name: Cetylpyridinium
MeSH_CUI: M0003973
MeSH_DUI: D002594
MeSH_Definition: Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.
MeSH_Name: Cetylpyridinium
NUI: N0000006978
RxNorm_CUI: 2286
RxNorm_Name: Cetylpyridinium
Synonym: Cetylpyridium
Synonym: Hexadecylpyridinium
Synonym: Pyridinium, 1-hexadecyl-
UMLS_CUI: C0007906
code: C24306
imported from: NDF-RT.owl

Tamoxifen [Chemical/Ingredient]
type: Class
subclass of: Stilbenes [Chemical/Ingredient]
Display_Name: Tamoxifen
MeSH_CUI: M0021024
MeSH_DUI: D013629
MeSH_Definition: One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
MeSH_Name: Tamoxifen
NUI: N0000007041
RxNorm_CUI: 10324
RxNorm_Name: Tamoxifen
Synonym: Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
UMLS_CUI: C0039286
code: C24432
imported from: NDF-RT.owl

Loperamide [Chemical/Ingredient]
type: Class
subclass of: Piperidines [Chemical/Ingredient]
Display_Name: Loperamide
MeSH_CUI: M0012692
MeSH_DUI: D008139
MeSH_Definition: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
MeSH_Name: Loperamide
NUI: N0000007084
RxNorm_CUI: 6468
RxNorm_Name: Loperamide
Synonym: 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-
UMLS_CUI: C0023992
code: C24520
imported from: NDF-RT.owl

Lovastatin [Chemical/Ingredient]
type: Class
subclass of: Naphthalenes [Chemical/Ingredient]
Display_Name: Lovastatin
MeSH_CUI: M0012707
MeSH_DUI: D008148
MeSH_Definition: A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
MeSH_Name: Lovastatin
NUI: N0000007106
RxNorm_CUI: 6472
RxNorm_Name: Lovastatin
Synonym: 6-Methylcompactin
Synonym: Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-
Synonym: Mevinolin
Synonym: Monacolin K
UMLS_CUI: C0024027
code: C24564
imported from: NDF-RT.owl

Fluphenazine [Chemical/Ingredient]
type: Class
subclass of: Phenothiazines [Chemical/Ingredient]
Display_Name: Fluphenazine
MeSH_CUI: M0008641
MeSH_DUI: D005476
MeSH_Definition: A phenothiazine used in the treatment of PSYCHOSES. Its properties and uses are generally similar to those of CHLORPROMAZINE.
MeSH_Name: Fluphenazine
NUI: N0000007109
RxNorm_CUI: 4496
RxNorm_Name: Fluphenazine
Synonym: 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-
Synonym: Flufenazin
UMLS_CUI: C0016368
code: C24570
imported from: NDF-RT.owl

Erythromycin [Chemical/Ingredient]
type: Class
subclass of: Macrolides [Chemical/Ingredient]
Display_Name: Erythromycin
MeSH_CUI: M0007715
MeSH_DUI: D004917
MeSH_Definition: A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
MeSH_Name: Erythromycin
NUI: N0000007133
RxNorm_CUI: 4053
RxNorm_Name: Erythromycin
Synonym: Erythromycin A
UMLS_CUI: C0014806
code: C24618
imported from: NDF-RT.owl

Thiethylperazine [Chemical/Ingredient]
type: Class
subclass of: Phenothiazines [Chemical/Ingredient]
subclass of: Piperazines [Chemical/Ingredient]
Display_Name: Thiethylperazine
MeSH_CUI: M0021336
MeSH_DUI: D013847
MeSH_Definition: A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
MeSH_Name: Thiethylperazine
NUI: N0000007176
RxNorm_CUI: 10471
RxNorm_Name: Thiethylperazine
Synonym: 10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-
Synonym: Novartis Brand of Thiethlperazine
UMLS_CUI: C0039865
code: C24704
imported from: NDF-RT.owl

Clomipramine [Chemical/Ingredient]
type: Class
subclass of: Dibenzazepines [Chemical/Ingredient]
Display_Name: Clomipramine
MeSH_CUI: M0004598
MeSH_DUI: D002997
MeSH_Definition: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
MeSH_Name: Clomipramine
NUI: N0000007182
RxNorm_CUI: 2597
RxNorm_Name: Clomipramine
Synonym: 5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-
Synonym: Chlomipramine
Synonym: Chlorimipramine
UMLS_CUI: C0009010
code: C24716
imported from: NDF-RT.owl

Hexachlorophene [Chemical/Ingredient]
type: Class
subclass of: Chlorophenols [Chemical/Ingredient]
Display_Name: Hexachlorophene
MeSH_CUI: M0010306
MeSH_DUI: D006582
MeSH_Definition: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
MeSH_Name: Hexachlorophene
NUI: N0000007260
RxNorm_CUI: 5293
RxNorm_Name: Hexachlorophene
Synonym: Hexachlorophane
Synonym: Phenol, 2,2'-methylenebis(3,4,6-trichloro)-
UMLS_CUI: C0019435
code: C24872
imported from: NDF-RT.owl

penciclovir [Chemical/Ingredient]
type: Class
subclass of: Acyclovir [Chemical/Ingredient]
Display_Name: penciclovir
MeSH_CUI: M0151646
MeSH_DUI: C053539
MeSH_Name: penciclovir
NUI: N0000007265
RxNorm_CUI: 59839
RxNorm_Name: penciclovir
Synonym: 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine
UMLS_CUI: C0164815
code: C24882
imported from: NDF-RT.owl

Acyclovir [Chemical/Ingredient]
type: Class
subclass of: Guanine [Chemical/Ingredient]
Display_Name: Acyclovir
MeSH_CUI: M0000326
MeSH_DUI: D000212
MeSH_Definition: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.
MeSH_Name: Acyclovir
NUI: N0000007269
RxNorm_CUI: 281
RxNorm_Name: Acyclovir
Synonym: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-
Synonym: 9-((2-Hydroxyethoxy)methyl)guanine
Synonym: Aciclovir
Synonym: Acycloguanosine
UMLS_CUI: C0001367
code: C24890
imported from: NDF-RT.owl

Thiothixene [Chemical/Ingredient]
type: Class
subclass of: Thioxanthenes [Chemical/Ingredient]
Display_Name: Thiothixene
MeSH_CUI: M0021384
MeSH_DUI: D013888
MeSH_Definition: A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
MeSH_Name: Thiothixene
NUI: N0000007308
RxNorm_CUI: 10510
RxNorm_Name: Thiothixene
Synonym: 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-
Synonym: Tiotixene
UMLS_CUI: C0039955
code: C24968
imported from: NDF-RT.owl

Adenine [Chemical/Ingredient]
type: Class
subclass of: Purines [Chemical/Ingredient]
Display_Name: Adenine
MeSH_CUI: M0000347
MeSH_DUI: D000225
MeSH_Definition: A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
MeSH_Name: Adenine
NUI: N0000007309
RxNorm_CUI: 290
RxNorm_Name: Adenine
Synonym: 1H-Purin-6-amine
Synonym: Vitamin B 4
UMLS_CUI: C0001407
code: C24970
imported from: NDF-RT.owl

Cyclosporine [Chemical/Ingredient]
type: Class
subclass of: Cyclosporins [Chemical/Ingredient]
Display_Name: Cyclosporine
MeSH_CUI: M0025279
MeSH_DUI: D016572
MeSH_Definition: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
MeSH_Name: Cyclosporine
NUI: N0000007346
RxNorm_CUI: 3008
RxNorm_Name: Cyclosporine
Synonym: Ciclosporin
Synonym: Cyclosporin
Synonym: Cyclosporin A
Synonym: Cyclosporine A
UMLS_CUI: C0010592
code: C25044
imported from: NDF-RT.owl

Astemizole [Chemical/Ingredient]
type: Class
subclass of: Benzimidazoles [Chemical/Ingredient]
Display_Name: Astemizole
MeSH_CUI: M0025303
MeSH_DUI: D016589
MeSH_Definition: A long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. The drug is well tolerated and has no anticholinergic side effects.
MeSH_Name: Astemizole
NUI: N0000007383
RxNorm_CUI: 42328
RxNorm_Name: Astemizole
Synonym: 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-
UMLS_CUI: C0085170
code: C25118
imported from: NDF-RT.owl

Terfenadine [Chemical/Ingredient]
type: Class
subclass of: Benzhydryl Compounds [Chemical/Ingredient]
subclass of: Piperidines [Chemical/Ingredient]
Display_Name: Terfenadine
MeSH_CUI: M0025307
MeSH_DUI: D016593
MeSH_Definition: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
MeSH_Name: Terfenadine
NUI: N0000007398
RxNorm_CUI: 42330
RxNorm_Name: Terfenadine
Synonym: 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-
Synonym: Terfenidine
Synonym: alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
UMLS_CUI: C0085173
code: C25148
imported from: NDF-RT.owl

Ritonavir [Chemical/Ingredient]
type: Class
subclass of: Thiazoles [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Ritonavir
MeSH_CUI: M0028918
MeSH_DUI: D019438
MeSH_Definition: An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV.
MeSH_Name: Ritonavir
NUI: N0000007423
RxNorm_CUI: 85762
RxNorm_Name: Ritonavir
UMLS_CUI: C0292818
code: C25198
imported from: NDF-RT.owl

Methylergonovine [Chemical/Ingredient]
type: Class
subclass of: Ergonovine [Chemical/Ingredient]
Display_Name: Methylergonovine
MeSH_CUI: M0013636
MeSH_DUI: D008755
MeSH_Definition: A homolog of ERGONOVINE containing one more CH2 group. (Merck Index, 11th ed)
MeSH_Name: Methylergonovine
NUI: N0000007462
RxNorm_CUI: 6883
RxNorm_Name: Methylergonovine
Synonym: Ergoline-8-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-6-methyl-, (8beta(S))-
Synonym: Methylergobasin
Synonym: Methylergometrin
Synonym: Methylergometrine
UMLS_CUI: C0025760
code: C25276
imported from: NDF-RT.owl

Carbolines [Chemical/Ingredient]
type: Class
subclass of: Pyridines [Chemical/Ingredient]
subclass of: Indoles [Chemical/Ingredient]
subclass of: Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Carbolines
MeSH_CUI: M0003364
MeSH_DUI: D002243
MeSH_Definition: A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.
MeSH_Name: Carbolines
NUI: N0000007499
RxNorm_CUI: 2030
Synonym: Pyrido(4,3-b)Indoles
UMLS_CUI: C0007007
code: C25354
imported from: NDF-RT.owl

Alkaloids [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Alkaloids
MeSH_CUI: M0000713
MeSH_DUI: D000470
MeSH_Definition: Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Alkaloids
NUI: N0000007503
RxNorm_CUI: 496
UMLS_CUI: C0002062
code: C25362
imported from: NDF-RT.owl

Anilides [Chemical/Ingredient]
type: Class
subclass of: Amides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Anilides
MeSH_CUI: M0001214
MeSH_DUI: D000813
MeSH_Name: Anilides
NUI: N0000007515
RxNorm_CUI: 842
UMLS_CUI: C0003035
code: C25386
imported from: NDF-RT.owl

Benzamides [Chemical/Ingredient]
type: Class
subclass of: Amides [Chemical/Ingredient]
subclass of: Benzoic Acids [Chemical/Ingredient]
Display_Name: Benzamides
MeSH_CUI: M0002327
MeSH_DUI: D001549
MeSH_Definition: BENZOIC ACID amides.
MeSH_Name: Benzamides
NUI: N0000007520
RxNorm_CUI: 1381
UMLS_CUI: C0005029
code: C25396
imported from: NDF-RT.owl

Benzazepines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Benzazepines
MeSH_CUI: M0002330
MeSH_DUI: D001552
MeSH_Definition: Compounds with BENZENE fused to AZEPINES.
MeSH_Name: Benzazepines
NUI: N0000007524
RxNorm_CUI: 1384
UMLS_CUI: C0005034
code: C25404
imported from: NDF-RT.owl

Benzene Derivatives [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Aromatic [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Benzene Derivatives
MeSH_CUI: M0002333
MeSH_DUI: D001555
MeSH_Name: Benzene Derivatives
NUI: N0000007525
RxNorm_CUI: 1387
UMLS_CUI: C0005037
code: C25406
imported from: NDF-RT.owl

Benzhydryl Compounds [Chemical/Ingredient]
type: Class
subclass of: Benzene Derivatives [Chemical/Ingredient]
Display_Name: Benzhydryl Compounds
MeSH_CUI: M0002345
MeSH_DUI: D001559
MeSH_Definition: Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.
MeSH_Name: Benzhydryl Compounds
NUI: N0000007528
RxNorm_CUI: 1392
Synonym: Diphenylmethyl Compounds
UMLS_CUI: C0005046
code: C25412
imported from: NDF-RT.owl

Macrolides [Chemical/Ingredient]
type: Class
subclass of: Lactones [Chemical/Ingredient]
subclass of: Glycosides [Chemical/Ingredient]
subclass of: Macrocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Macrolides
MeSH_CUI: M0028311
MeSH_DUI: D018942
MeSH_Definition: A group of macrocyclic compounds formed by chain extension of multiple PROPIONATES and cyclized into a large (typically 12, 14, 16) membered lactone. They are often glycosylated. Many of them are ANTIBIOTICS.
MeSH_Name: Macrolides
NUI: N0000007529
RxNorm_CUI: 586370
UMLS_CUI: C0282563
code: C25414
imported from: NDF-RT.owl

Spiro Compounds [Chemical/Ingredient]
type: Class
subclass of: Polycyclic Hydrocarbons, Aromatic [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Spiro Compounds
MeSH_CUI: M0020345
MeSH_DUI: D013141
MeSH_Definition: A group of compounds consisting in part of two rings sharing one carbon atom in common.
MeSH_Name: Spiro Compounds
NUI: N0000007532
RxNorm_CUI: 9993
UMLS_CUI: C0037968
code: C25420
imported from: NDF-RT.owl

Digitalis Glycosides [Chemical/Ingredient]
type: Class
subclass of: Cardenolides [Chemical/Ingredient]
Display_Name: Digitalis Glycosides
MeSH_CUI: M0006379
MeSH_DUI: D004071
MeSH_Definition: Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
MeSH_Name: Digitalis Glycosides
NUI: N0000007534
RxNorm_CUI: 3400
UMLS_CUI: C0012253
code: C25424
imported from: NDF-RT.owl

Benzimidazoles [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Benzimidazoles
MeSH_CUI: M0002348
MeSH_DUI: D001562
MeSH_Definition: Compounds with a BENZENE fused to IMIDAZOLES.
MeSH_Name: Benzimidazoles
NUI: N0000007536
RxNorm_CUI: 1396
UMLS_CUI: C0005050
code: C25428
imported from: NDF-RT.owl

Phenols [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
Display_Name: Phenols
MeSH_CUI: M0016520
MeSH_DUI: D010636
MeSH_Name: Phenols
NUI: N0000007540
RxNorm_CUI: 8140
Synonym: Carbol
UMLS_CUI: C0031428
code: C25436
imported from: NDF-RT.owl

Benzodiazepines [Chemical/Ingredient]
type: Class
subclass of: Benzazepines [Chemical/Ingredient]
Display_Name: Benzodiazepines
MeSH_CUI: M0002356
MeSH_DUI: D001569
MeSH_Definition: A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
MeSH_Name: Benzodiazepines
NUI: N0000007542
RxNorm_CUI: 1402
Synonym: Benzodiazepine
Synonym: Benzodiazepine Compounds
UMLS_CUI: C0005064
code: C25440
imported from: NDF-RT.owl

Cardenolides [Chemical/Ingredient]
type: Class
subclass of: Cardiac Glycosides [Chemical/Ingredient]
Display_Name: Cardenolides
MeSH_CUI: M0003448
MeSH_DUI: D002298
MeSH_Definition: C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
MeSH_Name: Cardenolides
NUI: N0000007543
RxNorm_CUI: 2078
UMLS_CUI: C0007143
code: C25442
imported from: NDF-RT.owl

Phenothiazines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]
subclass of: Sulfur Compounds [Chemical/Ingredient]
Display_Name: Phenothiazines
MeSH_CUI: M0016525
MeSH_DUI: D010640
MeSH_Definition: Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.
MeSH_Name: Phenothiazines
NUI: N0000007544
RxNorm_CUI: 8146
UMLS_CUI: C0031436
code: C25444
imported from: NDF-RT.owl

Benzofurans [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Benzofurans
MeSH_CUI: M0002359
MeSH_DUI: D001572
MeSH_Definition: Compounds that contain a BENZENE ring fused to a furan ring.
MeSH_Name: Benzofurans
NUI: N0000007548
RxNorm_CUI: 1405
Synonym: Coumarones
UMLS_CUI: C0005068
code: C25452
imported from: NDF-RT.owl

Benzopyrans [Chemical/Ingredient]
type: Class
subclass of: Pyrans [Chemical/Ingredient]
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Benzopyrans
MeSH_CUI: M0002367
MeSH_DUI: D001578
MeSH_Definition: Compounds with a core of fused benzo-pyran rings.
MeSH_Name: Benzopyrans
NUI: N0000007553
RxNorm_CUI: 1411
Synonym: Chromenes
UMLS_CUI: C0005078
code: C25462
imported from: NDF-RT.owl

Benztropine [Chemical/Ingredient]
type: Class
subclass of: Tropanes [Chemical/Ingredient]
Display_Name: Benztropine
MeSH_CUI: M0002383
MeSH_DUI: D001590
MeSH_Definition: A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.
MeSH_Name: Benztropine
NUI: N0000007558
RxNorm_CUI: 1424
RxNorm_Name: Benztropine
Synonym: 8-Azabicyclo(3.2.1)octane, 3-(diphenylmethoxy)-8-methyl-, endo-
Synonym: Benzatropine
UMLS_CUI: C0005098
code: C25472
imported from: NDF-RT.owl

Triazoles [Chemical/Ingredient]
type: Class
subclass of: Azoles [Chemical/Ingredient]
Display_Name: Triazoles
MeSH_CUI: M0021911
MeSH_DUI: D014230
MeSH_Name: Triazoles
NUI: N0000007567
RxNorm_CUI: 10768
UMLS_CUI: C0040880
code: C25490
imported from: NDF-RT.owl

Pyrazoles [Chemical/Ingredient]
type: Class
subclass of: Azoles [Chemical/Ingredient]
Display_Name: Pyrazoles
MeSH_CUI: M0018226
MeSH_DUI: D011720
MeSH_Definition: Azoles of two nitrogens at the 1,2 positions, next to each other, in contrast with IMIDAZOLES in which they are at the 1,3 positions.
MeSH_Name: Pyrazoles
NUI: N0000007569
RxNorm_CUI: 8989
UMLS_CUI: C0034242
code: C25494
imported from: NDF-RT.owl

Pyridines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Pyridines
MeSH_CUI: M0018233
MeSH_DUI: D011725
MeSH_Definition: Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
MeSH_Name: Pyridines
NUI: N0000007570
RxNorm_CUI: 8995
UMLS_CUI: C0034255
code: C25496
imported from: NDF-RT.owl

Pyridinium Compounds [Chemical/Ingredient]
type: Class
subclass of: Pyridines [Chemical/Ingredient]
Display_Name: Pyridinium Compounds
MeSH_CUI: M0018234
MeSH_DUI: D011726
MeSH_Name: Pyridinium Compounds
NUI: N0000007571
RxNorm_CUI: 8996
UMLS_CUI: C0034256
code: C25498
imported from: NDF-RT.owl

Salicylamides [Chemical/Ingredient]
type: Class
subclass of: Amides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Salicylamides
MeSH_CUI: M0019360
MeSH_DUI: D012457
MeSH_Definition: Amides of salicylic acid.
MeSH_Name: Salicylamides
NUI: N0000007577
RxNorm_CUI: 9519
UMLS_CUI: C0036072
code: C25510
imported from: NDF-RT.owl

Salicylanilides [Chemical/Ingredient]
type: Class
subclass of: Anilides [Chemical/Ingredient]
subclass of: Salicylamides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Salicylanilides
MeSH_CUI: M0019361
MeSH_DUI: D012458
MeSH_Definition: 2-Hydroxy-N-phenylbenzamides. N-phenyl substituted salicylamides. Derivatives have been used as fungicides, anti-mildew agents and topical antifungal agents. In concentrated form may cause irritation of skin and mucous membranes.
MeSH_Name: Salicylanilides
NUI: N0000007578
RxNorm_CUI: 9521
Synonym: N-Phenylsalicylamides
UMLS_CUI: C0036074
code: C25512
imported from: NDF-RT.owl

Pyrimidines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
Display_Name: Pyrimidines
MeSH_CUI: M0018260
MeSH_DUI: D011743
MeSH_Definition: A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
MeSH_Name: Pyrimidines
NUI: N0000007587
RxNorm_CUI: 9015
UMLS_CUI: C0034289
code: C25530
imported from: NDF-RT.owl

Pyrimidinones [Chemical/Ingredient]
type: Class
subclass of: Pyrimidines [Chemical/Ingredient]
Display_Name: Pyrimidinones
MeSH_CUI: M0018261
MeSH_DUI: D011744
MeSH_Name: Pyrimidinones
NUI: N0000007588
RxNorm_CUI: 9016
UMLS_CUI: C0034290
code: C25532
imported from: NDF-RT.owl

Pyrrolidines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Pyrrolidines
MeSH_CUI: M0018277
MeSH_DUI: D011759
MeSH_Name: Pyrrolidines
NUI: N0000007593
RxNorm_CUI: 9034
UMLS_CUI: C0034326
code: C25542
imported from: NDF-RT.owl

Interferon Type I, Recombinant [Chemical/Ingredient]
type: Class
subclass of: Interferon Type I [Chemical/Ingredient]
subclass of: Recombinant Proteins [Chemical/Ingredient]
Display_Name: Interferon Type I, Recombinant
MeSH_CUI: M0023692
MeSH_DUI: D015379
MeSH_Definition: A type I interferon with antiviral and antineoplastic activity produced by recombinant DNA technology. It can be a mixture of alpha and beta interferons.
MeSH_Name: Interferon Type I, Recombinant
NUI: N0000007612
RxNorm_CUI: 5878
UMLS_CUI: C0021733
code: C25584
imported from: NDF-RT.owl

Interferon Type I [Chemical/Ingredient]
type: Class
subclass of: Interferons [Chemical/Ingredient]
Display_Name: Interferon Type I
MeSH_CUI: M0011489
MeSH_DUI: D007370
MeSH_Definition: Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA).
MeSH_Name: Interferon Type I
NUI: N0000007614
RxNorm_CUI: 5884
Synonym: Interferons Type I
Synonym: Type I Interferon
Synonym: Type I Interferons
UMLS_CUI: C0021743
code: C25588
imported from: NDF-RT.owl

Ergolines [Chemical/Ingredient]
type: Class
subclass of: Ergot Alkaloids [Chemical/Ingredient]
subclass of: Heterocyclic Compounds with 4 or More Rings [Chemical/Ingredient]
Display_Name: Ergolines
MeSH_CUI: M0007652
MeSH_DUI: D004873
MeSH_Definition: A series of structurally-related alkaloids that contain the ergoline backbone structure.
MeSH_Name: Ergolines
NUI: N0000007618
RxNorm_CUI: 4020
UMLS_CUI: C0014699
code: C25596
imported from: NDF-RT.owl

Ergonovine [Chemical/Ingredient]
type: Class
subclass of: Ergolines [Chemical/Ingredient]
Display_Name: Ergonovine
MeSH_CUI: M0007653
MeSH_DUI: D004874
MeSH_Definition: An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
MeSH_Name: Ergonovine
NUI: N0000007619
RxNorm_CUI: 4021
RxNorm_Name: Ergonovine
Synonym: Ergobasin
Synonym: Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, (8beta(S))-
Synonym: Ergometrin
Synonym: Ergometrine
UMLS_CUI: C0014704
code: C25598
imported from: NDF-RT.owl

Ergot Alkaloids [Chemical/Ingredient]
type: Class
subclass of: Alkaloids [Chemical/Ingredient]
Display_Name: Ergot Alkaloids
MeSH_CUI: M0007656
MeSH_DUI: D004876
MeSH_Definition: Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include compounds that are structurally related to ergoline (ERGOLINES) and ergotamine (ERGOTAMINES). Many of the ergot alkaloids act as alpha-adrenergic antagonists.
MeSH_Name: Ergot Alkaloids
NUI: N0000007620
RxNorm_CUI: 4023
RxNorm_Name: Ergot Alkaloids
Synonym: Clavine Alkaloids
Synonym: Ergots
UMLS_CUI: C0014707
code: C25600
imported from: NDF-RT.owl

Ergotamines [Chemical/Ingredient]
type: Class
subclass of: Ergot Alkaloids [Chemical/Ingredient]
subclass of: Heterocyclic Compounds with 4 or More Rings [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Ergotamines
MeSH_CUI: M0007665
MeSH_DUI: D004879
MeSH_Definition: A series of structurally-related alkaloids containing the ergotaman backbone structure.
MeSH_Name: Ergotamines
NUI: N0000007621
RxNorm_CUI: 4026
UMLS_CUI: C0014711
code: C25602
imported from: NDF-RT.owl

Mycophenolic Acid [Chemical/Ingredient]
type: Class
subclass of: Caproates [Chemical/Ingredient]
Display_Name: Mycophenolic Acid
MeSH_CUI: M0014304
MeSH_DUI: D009173
MeSH_Definition: An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)
MeSH_Name: Mycophenolic Acid
NUI: N0000007622
RxNorm_CUI: 7145
RxNorm_Name: Mycophenolic Acid
Synonym: -Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
UMLS_CUI: C0026933
code: C25604
imported from: NDF-RT.owl

Acids, Acyclic [Chemical/Ingredient]
type: Class
subclass of: Carboxylic Acids [Chemical/Ingredient]
Display_Name: Acids, Acyclic
MeSH_CUI: M0000221
MeSH_DUI: D000144
MeSH_Definition: Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures.
MeSH_Name: Acids, Acyclic
NUI: N0000007627
RxNorm_CUI: 231
Synonym: Acyclic Acids
UMLS_CUI: C0001129
code: C25614
imported from: NDF-RT.owl

Acids, Carbocyclic [Chemical/Ingredient]
type: Class
subclass of: Carboxylic Acids [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Acids, Carbocyclic
MeSH_CUI: M0000223
MeSH_DUI: D000146
MeSH_Definition: Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon.
MeSH_Name: Acids, Carbocyclic
NUI: N0000007628
RxNorm_CUI: 233
Synonym: Carbocyclic Acids
UMLS_CUI: C0001131
code: C25616
imported from: NDF-RT.owl

Lactones [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Lactones
MeSH_CUI: M0012175
MeSH_DUI: D007783
MeSH_Definition: Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
MeSH_Name: Lactones
NUI: N0000007646
RxNorm_CUI: 6209
UMLS_CUI: C0022947
code: C25652
imported from: NDF-RT.owl

Interferon-beta [Chemical/Ingredient]
type: Class
subclass of: Interferon Type I [Chemical/Ingredient]
Display_Name: Interferon-beta
MeSH_CUI: M0025715
MeSH_DUI: D016899
MeSH_Definition: One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity.
MeSH_Name: Interferon-beta
NUI: N0000007668
RxNorm_CUI: 4381
RxNorm_Name: Interferon-beta
Synonym: Interferon, Fibroblast
Synonym: Interferon, beta
Synonym: beta-Interferon
UMLS_CUI: C0015980
code: C25696
imported from: NDF-RT.owl

Organic Chemicals [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Organic Chemicals
MeSH_CUI: M0015401
MeSH_DUI: D009930
MeSH_Definition: A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.
MeSH_Name: Organic Chemicals
NUI: N0000007676
RxNorm_CUI: 7692
UMLS_CUI: C0029224
code: C25712
imported from: NDF-RT.owl

Propiophenones [Chemical/Ingredient]
type: Class
subclass of: Ketones [Chemical/Ingredient]
Display_Name: Propiophenones
MeSH_CUI: M0017764
MeSH_DUI: D011427
MeSH_Name: Propiophenones
NUI: N0000007679
RxNorm_CUI: 8780
UMLS_CUI: C0033483
code: C25718
imported from: NDF-RT.owl

Amides [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Amides
MeSH_CUI: M0000897
MeSH_DUI: D000577
MeSH_Definition: Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Amides
NUI: N0000007681
RxNorm_CUI: 633
UMLS_CUI: C0002482
code: C25722
imported from: NDF-RT.owl

Propylamines [Chemical/Ingredient]
type: Class
subclass of: Amines [Chemical/Ingredient]
Display_Name: Propylamines
MeSH_CUI: M0017781
MeSH_DUI: D011437
MeSH_Name: Propylamines
NUI: N0000007691
RxNorm_CUI: 8790
UMLS_CUI: C0033504
code: C25742
imported from: NDF-RT.owl

Benzoic Acids [Chemical/Ingredient]
type: Class
subclass of: Acids, Carbocyclic [Chemical/Ingredient]
Display_Name: Benzoic Acids
MeSH_CUI: M0029896
MeSH_DUI: D020185
MeSH_Definition: Acids, salts, and derivatives of BENZOIC ACID.
MeSH_Name: Benzoic Acids
NUI: N0000007692
RxNorm_CUI: 155099
UMLS_CUI: C0600423
code: C25744
imported from: NDF-RT.owl

Steroids [Chemical/Ingredient]
type: Class
subclass of: Polycyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Steroids
MeSH_CUI: M0020527
MeSH_DUI: D013256
MeSH_Definition: A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
MeSH_Name: Steroids
NUI: N0000007720
RxNorm_CUI: 10072
UMLS_CUI: C0038317
code: C25800
imported from: NDF-RT.owl

Quinidine [Chemical/Ingredient]
type: Class
subclass of: Quinolines [Chemical/Ingredient]
subclass of: Quinuclidines [Chemical/Ingredient]
subclass of: Cinchona Alkaloids [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Quinidine
MeSH_CUI: M0018341
MeSH_DUI: D011802
MeSH_Definition: An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
MeSH_Name: Quinidine
NUI: N0000007728
RxNorm_CUI: 9068
RxNorm_Name: Quinidine
Synonym: Chinidin
Synonym: Cinchonan-9-ol, 6'-methoxy-, (9S)-
UMLS_CUI: C0034414
code: C25816
imported from: NDF-RT.owl

Quinolines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Quinolines
MeSH_CUI: M0018350
MeSH_DUI: D011804
MeSH_Name: Quinolines
NUI: N0000007731
RxNorm_CUI: 9077
UMLS_CUI: C0034424
code: C25822
imported from: NDF-RT.owl

Chlorophenols [Chemical/Ingredient]
type: Class
subclass of: Phenols [Chemical/Ingredient]
subclass of: Chlorobenzenes [Chemical/Ingredient]
Display_Name: Chlorophenols
MeSH_CUI: M0004174
MeSH_DUI: D002733
MeSH_Definition: Phenols substituted with one or more chlorine atoms in any position.
MeSH_Name: Chlorophenols
NUI: N0000007732
RxNorm_CUI: 2387
Synonym: Hydroxychlorobenzenes
UMLS_CUI: C0008257
code: C25824
imported from: NDF-RT.owl

Stilbenes [Chemical/Ingredient]
type: Class
subclass of: Benzylidene Compounds [Chemical/Ingredient]
Display_Name: Stilbenes
MeSH_CUI: M0020537
MeSH_DUI: D013267
MeSH_Definition: Organic compounds that contain 1,2-diphenylethylene as a functional group.
MeSH_Name: Stilbenes
NUI: N0000007736
RxNorm_CUI: 10081
UMLS_CUI: C0038333
code: C25832
imported from: NDF-RT.owl

Chloroquine [Chemical/Ingredient]
type: Class
subclass of: Aminoquinolines [Chemical/Ingredient]
Display_Name: Chloroquine
MeSH_CUI: M0004182
MeSH_DUI: D002738
MeSH_Definition: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
MeSH_Name: Chloroquine
NUI: N0000007737
RxNorm_CUI: 2393
RxNorm_Name: Chloroquine
Synonym: 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-
Synonym: Chingamin
Synonym: Chlorochin
Synonym: Khingamin
UMLS_CUI: C0008269
code: C25834
imported from: NDF-RT.owl

Quinuclidines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, Bridged-Ring [Chemical/Ingredient]
Display_Name: Quinuclidines
MeSH_CUI: M0018359
MeSH_DUI: D011812
MeSH_Name: Quinuclidines
NUI: N0000007740
RxNorm_CUI: 9086
UMLS_CUI: C0034439
code: C25840
imported from: NDF-RT.owl

Tropanes [Chemical/Ingredient]
type: Class
subclass of: Alkaloids [Chemical/Ingredient]
subclass of: Azabicyclo Compounds [Chemical/Ingredient]
Display_Name: Tropanes
MeSH_CUI: M0022031
MeSH_DUI: D014326
MeSH_Definition: N-methyl-8-azabicyclo[3.2.1]octanes best known for the ones found in PLANTS.
MeSH_Name: Tropanes
NUI: N0000007744
RxNorm_CUI: 10866
UMLS_CUI: C0041177
code: C25848
imported from: NDF-RT.owl

2-Aminopurine [Chemical/Ingredient]
type: Class
subclass of: Adenine [Chemical/Ingredient]
Display_Name: 2-Aminopurine
MeSH_CUI: M0023189
MeSH_DUI: D015075
MeSH_Definition: A purine that is an isomer of ADENINE (6-aminopurine).
MeSH_Name: 2-Aminopurine
NUI: N0000007749
RxNorm_CUI: 37
Synonym: 1H-Purin-2-amine
UMLS_CUI: C0000263
code: C25858
imported from: NDF-RT.owl

Deoxycytidine [Chemical/Ingredient]
type: Class
subclass of: Deoxyribonucleosides [Chemical/Ingredient]
subclass of: Cytidine [Chemical/Ingredient]
Display_Name: Deoxycytidine
MeSH_CUI: M0005997
MeSH_DUI: D003841
MeSH_Name: Deoxycytidine
NUI: N0000007762
RxNorm_CUI: 3195
Synonym: CDR
Synonym: Cytidine, 2'-deoxy-
Synonym: Cytosine Deoxyribonucleoside
Synonym: Cytosine Deoxyriboside
UMLS_CUI: C0011485
code: C25884
imported from: NDF-RT.owl

Deoxyribonucleosides [Chemical/Ingredient]
type: Class
subclass of: Nucleosides [Chemical/Ingredient]
Display_Name: Deoxyribonucleosides
MeSH_CUI: M0006016
MeSH_DUI: D003853
MeSH_Definition: A purine or pyrimidine base bonded to DEOXYRIBOSE.
MeSH_Name: Deoxyribonucleosides
NUI: N0000007768
RxNorm_CUI: 3215
UMLS_CUI: C0011528
code: C25896
imported from: NDF-RT.owl

Imidazoles [Chemical/Ingredient]
type: Class
subclass of: Azoles [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Imidazoles
MeSH_CUI: M0011048
MeSH_DUI: D007093
MeSH_Definition: Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
MeSH_Name: Imidazoles
NUI: N0000007769
RxNorm_CUI: 5684
UMLS_CUI: C0020924
code: C25898
imported from: NDF-RT.owl

Furans [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Furans
MeSH_CUI: M0008898
MeSH_DUI: D005663
MeSH_Definition: Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.
MeSH_Name: Furans
NUI: N0000007775
RxNorm_CUI: 4600
UMLS_CUI: C0016850
code: C25910
imported from: NDF-RT.owl

Adamantane [Chemical/Ingredient]
type: Class
subclass of: Cycloparaffins [Chemical/Ingredient]
subclass of: Bridged Compounds [Chemical/Ingredient]
Display_Name: Adamantane
MeSH_CUI: M0000336
MeSH_DUI: D000218
MeSH_Definition: A tricyclo bridged hydrocarbon.
MeSH_Name: Adamantane
NUI: N0000007793
RxNorm_CUI: 287
Synonym: Diamantane
Synonym: Tricyclo(3.3.1.1(3,7))decane
UMLS_CUI: C0001392
code: C25946
imported from: NDF-RT.owl

Naphthalenes [Chemical/Ingredient]
type: Class
subclass of: Polycyclic Hydrocarbons, Aromatic [Chemical/Ingredient]
Display_Name: Naphthalenes
MeSH_CUI: M0014459
MeSH_DUI: D009281
MeSH_Definition: Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
MeSH_Name: Naphthalenes
NUI: N0000007809
RxNorm_CUI: 7251
UMLS_CUI: C0027378
code: C25978
imported from: NDF-RT.owl

Bicyclo Compounds, Heterocyclic [Chemical/Ingredient]
type: Class
subclass of: Bicyclo Compounds [Chemical/Ingredient]
subclass of: Heterocyclic Compounds, Bridged-Ring [Chemical/Ingredient]
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Bicyclo Compounds, Heterocyclic
MeSH_CUI: M0028488
MeSH_DUI: D019086
MeSH_Definition: A class of saturated compounds consisting of two rings only, having two or more atoms in common, containing at least one hetero atom, and that take the name of an open chain hydrocarbon containing the same total number of atoms. (From Riguady et al., Nomenclature of Organic Chemistry, 1979, p31)
MeSH_Name: Bicyclo Compounds, Heterocyclic
NUI: N0000007813
RxNorm_CUI: 82186
Synonym: Bicyclic Heterocyclic Compounds
Synonym: Heterocyclic Bicyclo Compounds
Synonym: Heterocyclic Cpds, Bicyclic
UMLS_CUI: C0282650
code: C25986
imported from: NDF-RT.owl

Amino Acids, Peptides, and Proteins [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Amino Acids, Peptides, and Proteins
MeSH_CUI: M0000928
MeSH_DUI: D000602
MeSH_Definition: Amino acids and chains of amino acids connected by peptide linkages.
MeSH_Name: Amino Acids, Peptides, and Proteins
NUI: N0000007833
RxNorm_CUI: 664
UMLS_CUI: C0002526
code: C26026
imported from: NDF-RT.owl

Aminopyridines [Chemical/Ingredient]
type: Class
subclass of: Pyridines [Chemical/Ingredient]
subclass of: Amines [Chemical/Ingredient]
Display_Name: Aminopyridines
MeSH_CUI: M0000964
MeSH_DUI: D000631
MeSH_Definition: Pyridines substituted in any position with an amino group. May be hydrogenated, but must retain at least one double bond.
MeSH_Name: Aminopyridines
NUI: N0000007862
RxNorm_CUI: 694
UMLS_CUI: C0002585
code: C26084
imported from: NDF-RT.owl

Aminoquinolines [Chemical/Ingredient]
type: Class
subclass of: Quinolines [Chemical/Ingredient]
Display_Name: Aminoquinolines
MeSH_CUI: M0000967
MeSH_DUI: D000634
MeSH_Definition: Quinolines substituted in any position by one or more amino groups.
MeSH_Name: Aminoquinolines
NUI: N0000007864
RxNorm_CUI: 697
UMLS_CUI: C0002588
code: C26088
imported from: NDF-RT.owl

Peptides [Chemical/Ingredient]
type: Class
subclass of: Amino Acids, Peptides, and Proteins [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Peptides
MeSH_CUI: M0016238
MeSH_DUI: D010455
MeSH_Definition: Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
MeSH_Name: Peptides
NUI: N0000007874
RxNorm_CUI: 8036
UMLS_CUI: C0030956
code: C26108
imported from: NDF-RT.owl

Peptides, Cyclic [Chemical/Ingredient]
type: Class
subclass of: Peptides [Chemical/Ingredient]
subclass of: Macrocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Peptides, Cyclic
MeSH_CUI: M0016239
MeSH_DUI: D010456
MeSH_Definition: Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).
MeSH_Name: Peptides, Cyclic
NUI: N0000007875
RxNorm_CUI: 8037
Synonym: Cyclic Peptides
UMLS_CUI: C0030957
code: C26110
imported from: NDF-RT.owl

Glycopeptides [Chemical/Ingredient]
type: Class
subclass of: Peptides [Chemical/Ingredient]
subclass of: Glycoconjugates [Chemical/Ingredient]
Display_Name: Glycopeptides
MeSH_CUI: M0009481
MeSH_DUI: D006020
MeSH_Definition: Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight.
MeSH_Name: Glycopeptides
NUI: N0000007889
RxNorm_CUI: 4944
UMLS_CUI: C0017953
code: C26138
imported from: NDF-RT.owl

Ribonucleosides [Chemical/Ingredient]
type: Class
subclass of: Nucleosides [Chemical/Ingredient]
Display_Name: Ribonucleosides
MeSH_CUI: M0019074
MeSH_DUI: D012263
MeSH_Definition: Nucleosides in which the purine or pyrimidine base is combined with ribose. (Dorland, 28th ed)
MeSH_Name: Ribonucleosides
NUI: N0000007894
RxNorm_CUI: 9356
UMLS_CUI: C0035546
code: C26148
imported from: NDF-RT.owl

Cycloparaffins [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Alicyclic [Chemical/Ingredient]
subclass of: Macrocyclic Compounds [Chemical/Ingredient]
Display_Name: Cycloparaffins
MeSH_CUI: M0005477
MeSH_DUI: D003516
MeSH_Definition: Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)
MeSH_Name: Cycloparaffins
NUI: N0000007896
RxNorm_CUI: 2997
Synonym: Cyclic Olefins
Synonym: Cycloalkanes
UMLS_CUI: C0010578
code: C26152
imported from: NDF-RT.owl

Glycosides [Chemical/Ingredient]
type: Class
subclass of: Carbohydrates [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Glycosides
MeSH_CUI: M0009500
MeSH_DUI: D006027
MeSH_Definition: Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
MeSH_Name: Glycosides
NUI: N0000007897
RxNorm_CUI: 4958
UMLS_CUI: C0017977
code: C26154
imported from: NDF-RT.owl

Cyclosporins [Chemical/Ingredient]
type: Class
subclass of: Peptides, Cyclic [Chemical/Ingredient]
Display_Name: Cyclosporins
MeSH_CUI: M0005493
MeSH_DUI: D003524
MeSH_Definition: A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
MeSH_Name: Cyclosporins
NUI: N0000007903
RxNorm_CUI: 3009
Synonym: Cyclosporines
UMLS_CUI: C0010594
code: C26166
imported from: NDF-RT.owl

4-Hydroxycoumarins [Chemical/Ingredient]
type: Class
subclass of: Coumarins [Chemical/Ingredient]
Display_Name: 4-Hydroxycoumarins
MeSH_CUI: M0023241
MeSH_DUI: D015110
MeSH_Definition: Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants.
MeSH_Name: 4-Hydroxycoumarins
NUI: N0000007905
RxNorm_CUI: 82
UMLS_CUI: C0000506
code: C26170
imported from: NDF-RT.owl

Cytidine [Chemical/Ingredient]
type: Class
subclass of: Ribonucleosides [Chemical/Ingredient]
subclass of: Pyrimidine Nucleosides [Chemical/Ingredient]
Display_Name: Cytidine
MeSH_CUI: M0005567
MeSH_DUI: D003562
MeSH_Definition: A pyrimidine nucleoside that is composed of the base CYTOSINE linked to the five-carbon sugar D-RIBOSE.
MeSH_Name: Cytidine
NUI: N0000007916
RxNorm_CUI: 3042
Synonym: Cytosine Ribonucleoside
Synonym: Cytosine Riboside
UMLS_CUI: C0010715
code: C26194
imported from: NDF-RT.owl

Piperazines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
Display_Name: Piperazines
MeSH_CUI: M0016884
MeSH_DUI: D010879
MeSH_Name: Piperazines
NUI: N0000007927
RxNorm_CUI: 8341
UMLS_CUI: C0031958
code: C26216
imported from: NDF-RT.owl

Piperidines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Piperidines
MeSH_CUI: M0016885
MeSH_DUI: D010880
MeSH_Definition: A family of hexahydropyridines.
MeSH_Name: Piperidines
NUI: N0000007929
RxNorm_CUI: 8343
UMLS_CUI: C0031960
code: C26220
imported from: NDF-RT.owl

Piperidones [Chemical/Ingredient]
type: Class
subclass of: Piperidines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Piperidones
MeSH_CUI: M0016886
MeSH_DUI: D010881
MeSH_Name: Piperidones
NUI: N0000007930
RxNorm_CUI: 8344
UMLS_CUI: C0031961
code: C26222
imported from: NDF-RT.owl

Recombinant Proteins [Chemical/Ingredient]
type: Class
subclass of: Proteins [Chemical/Ingredient]
Display_Name: Recombinant Proteins
MeSH_CUI: M0018641
MeSH_DUI: D011994
MeSH_Definition: Proteins prepared by recombinant DNA technology.
MeSH_Name: Recombinant Proteins
NUI: N0000007956
RxNorm_CUI: 9218
Synonym: Biosynthetic Proteins
Synonym: Proteins, Biosynthetic
UMLS_CUI: C0034861
code: C26276
imported from: NDF-RT.owl

Isoquinolines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
Display_Name: Isoquinolines
MeSH_CUI: M0011785
MeSH_DUI: D007546
MeSH_Definition: A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
MeSH_Name: Isoquinolines
NUI: N0000007960
RxNorm_CUI: 6056
UMLS_CUI: C0022248
code: C26284
imported from: NDF-RT.owl

Dibenzazepines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]
Display_Name: Dibenzazepines
MeSH_CUI: M0006249
MeSH_DUI: D003984
MeSH_Definition: Compounds with two BENZENE rings fused to AZEPINES.
MeSH_Name: Dibenzazepines
NUI: N0000007962
RxNorm_CUI: 3331
UMLS_CUI: C0012029
code: C26288
imported from: NDF-RT.owl

Hydrazines [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
Display_Name: Hydrazines
MeSH_CUI: M0010683
MeSH_DUI: D006834
MeSH_Name: Hydrazines
NUI: N0000007972
RxNorm_CUI: 5473
UMLS_CUI: C0020233
code: C26308
imported from: NDF-RT.owl

Hydrocarbons [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Hydrocarbons
MeSH_CUI: M0010687
MeSH_DUI: D006838
MeSH_Name: Hydrocarbons
NUI: N0000007973
RxNorm_CUI: 5476
UMLS_CUI: C0020242
code: C26310
imported from: NDF-RT.owl

Hydrocarbons, Chlorinated [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Halogenated [Chemical/Ingredient]
Display_Name: Hydrocarbons, Chlorinated
MeSH_CUI: M0010693
MeSH_DUI: D006843
MeSH_Definition: Hydrocarbon compounds with one or more of the hydrogens replaced by CHLORINE.
MeSH_Name: Hydrocarbons, Chlorinated
NUI: N0000007975
RxNorm_CUI: 5481
Synonym: Chlorinated Hydrocarbons
Synonym: Chlorine Compounds, Organic
Synonym: Organochlorine Compounds
UMLS_CUI: C0020247
code: C26314
imported from: NDF-RT.owl

Hydrocarbons, Halogenated [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons [Chemical/Ingredient]
Display_Name: Hydrocarbons, Halogenated
MeSH_CUI: M0010696
MeSH_DUI: D006846
MeSH_Name: Hydrocarbons, Halogenated
NUI: N0000007977
RxNorm_CUI: 5484
Synonym: Halogenated Hydrocarbons
UMLS_CUI: C0020250
code: C26318
imported from: NDF-RT.owl

Pregnadienes [Chemical/Ingredient]
type: Class
subclass of: Pregnanes [Chemical/Ingredient]
Display_Name: Pregnadienes
MeSH_CUI: M0017468
MeSH_DUI: D011245
MeSH_Definition: Pregnane derivatives containing two double bonds anywhere within the ring structures.
MeSH_Name: Pregnadienes
NUI: N0000008001
RxNorm_CUI: 8642
UMLS_CUI: C0032959
code: C26366
imported from: NDF-RT.owl

Pregnadienetriols [Chemical/Ingredient]
type: Class
subclass of: Pregnadienes [Chemical/Ingredient]
Display_Name: Pregnadienetriols
MeSH_CUI: M0017469
MeSH_DUI: D011246
MeSH_Definition: Doubly unsaturated pregnane derivatives substituted with three hydroxy groups anywhere within the ring structure or side chains.
MeSH_Name: Pregnadienetriols
NUI: N0000008002
RxNorm_CUI: 8643
Synonym: Trihydroxypregnadienes
UMLS_CUI: C0032960
code: C26368
imported from: NDF-RT.owl

Pregnenediones [Chemical/Ingredient]
type: Class
subclass of: Pregnenes [Chemical/Ingredient]
Display_Name: Pregnenediones
MeSH_CUI: M0017514
MeSH_DUI: D011282
MeSH_Definition: Unsaturated pregnane derivatives containing two keto groups on side chains or ring structures.
MeSH_Name: Pregnenediones
NUI: N0000008024
RxNorm_CUI: 8665
Synonym: Diketopregnenes
Synonym: Dioxopregnenes
UMLS_CUI: C0033013
code: C26412
imported from: NDF-RT.owl

Pregnenes [Chemical/Ingredient]
type: Class
subclass of: Pregnanes [Chemical/Ingredient]
Display_Name: Pregnenes
MeSH_CUI: M0017515
MeSH_DUI: D011283
MeSH_Definition: Unsaturated derivatives of PREGNANES.
MeSH_Name: Pregnenes
NUI: N0000008025
RxNorm_CUI: 8666
UMLS_CUI: C0033014
code: C26414
imported from: NDF-RT.owl

Guanine [Chemical/Ingredient]
type: Class
subclass of: Hypoxanthines [Chemical/Ingredient]
Display_Name: Guanine
MeSH_CUI: M0009679
MeSH_DUI: D006147
MeSH_Name: Guanine
NUI: N0000008039
RxNorm_CUI: 5039
Synonym: 6H-Purin-6-one, 2-amino-1,7-dihydro-
UMLS_CUI: C0018321
code: C26442
imported from: NDF-RT.owl

Sulfhydryl Compounds [Chemical/Ingredient]
type: Class
subclass of: Sulfur Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Sulfhydryl Compounds
MeSH_CUI: M0020768
MeSH_DUI: D013438
MeSH_Definition: Compounds containing the -SH radical.
MeSH_Name: Sulfhydryl Compounds
NUI: N0000008041
RxNorm_CUI: 10200
Synonym: Mercaptans
Synonym: Mercapto Compounds
Synonym: Thiols
UMLS_CUI: C0038734
code: C26446
imported from: NDF-RT.owl

Indoles [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Indoles
MeSH_CUI: M0011238
MeSH_DUI: D007211
MeSH_Definition: Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
MeSH_Name: Indoles
NUI: N0000008052
RxNorm_CUI: 5779
UMLS_CUI: C0021242
code: C26468
imported from: NDF-RT.owl

Cinchona Alkaloids [Chemical/Ingredient]
type: Class
subclass of: Alkaloids [Chemical/Ingredient]
Display_Name: Cinchona Alkaloids
MeSH_CUI: M0004487
MeSH_DUI: D002930
MeSH_Definition: Alkaloids extracted from various species of Cinchona.
MeSH_Name: Cinchona Alkaloids
NUI: N0000008058
RxNorm_CUI: 2545
UMLS_CUI: C0008792
code: C26480
imported from: NDF-RT.owl

Cinnamates [Chemical/Ingredient]
type: Class
subclass of: Acids, Carbocyclic [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cinnamates
MeSH_CUI: M0004490
MeSH_DUI: D002934
MeSH_Name: Cinnamates
NUI: N0000008060
RxNorm_CUI: 2547
UMLS_CUI: C0008801
code: C26484
imported from: NDF-RT.owl

Purines [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Purines
MeSH_CUI: M0018169
MeSH_DUI: D011687
MeSH_Definition: A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
MeSH_Name: Purines
NUI: N0000008065
RxNorm_CUI: 8952
UMLS_CUI: C0034140
code: C26494
imported from: NDF-RT.owl

Thiazoles [Chemical/Ingredient]
type: Class
subclass of: Azoles [Chemical/Ingredient]
subclass of: Sulfur Compounds [Chemical/Ingredient]
Display_Name: Thiazoles
MeSH_CUI: M0021333
MeSH_DUI: D013844
MeSH_Name: Thiazoles
NUI: N0000008087
RxNorm_CUI: 10468
UMLS_CUI: C0039859
code: C26538
imported from: NDF-RT.owl

Heterocyclic Compounds [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Heterocyclic Compounds
MeSH_CUI: M0010290
MeSH_DUI: D006571
MeSH_Definition: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Heterocyclic Compounds
NUI: N0000008095
RxNorm_CUI: 5283
UMLS_CUI: C0019398
code: C26554
imported from: NDF-RT.owl

Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Heterocyclic Compounds, 3-Ring
MeSH_CUI: M0010294
MeSH_DUI: D006575
MeSH_Definition: A class of organic compounds containing three ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic
MeSH_Name: Heterocyclic Compounds, 3-Ring
NUI: N0000008096
RxNorm_CUI: 5286
Synonym: Heterocyclic Cpds, 3 Ring
UMLS_CUI: C0019401
code: C26556
imported from: NDF-RT.owl

Hydroxyprogesterones [Chemical/Ingredient]
type: Class
subclass of: Progesterone [Chemical/Ingredient]
Display_Name: Hydroxyprogesterones
MeSH_CUI: M0010776
MeSH_DUI: D006908
MeSH_Definition: Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.
MeSH_Name: Hydroxyprogesterones
NUI: N0000008102
RxNorm_CUI: 5542
RxNorm_Name: Hydroxyprogesterone
UMLS_CUI: C0020387
code: C26568
imported from: NDF-RT.owl

Thioxanthenes [Chemical/Ingredient]
type: Class
subclass of: Xanthenes [Chemical/Ingredient]
subclass of: Sulfur Compounds [Chemical/Ingredient]
Display_Name: Thioxanthenes
MeSH_CUI: M0021388
MeSH_DUI: D013892
MeSH_Definition: Compounds with three aromatic rings in linear arrangement with a SULFUR in the center ring.
MeSH_Name: Thioxanthenes
NUI: N0000008107
RxNorm_CUI: 10516
UMLS_CUI: C0039961
code: C26578
imported from: NDF-RT.owl

Ketones [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
Display_Name: Ketones
MeSH_CUI: M0011995
MeSH_DUI: D007659
MeSH_Name: Ketones
NUI: N0000008109
RxNorm_CUI: 6141
UMLS_CUI: C0022634
code: C26582
imported from: NDF-RT.owl

Xanthenes [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]
Display_Name: Xanthenes
MeSH_CUI: M0023042
MeSH_DUI: D014966
MeSH_Definition: Compounds with three aromatic rings in linear arrangement with an OXYGEN in the center ring.
MeSH_Name: Xanthenes
NUI: N0000008115
RxNorm_CUI: 11352
UMLS_CUI: C0043313
code: C26594
imported from: NDF-RT.owl

Caproates [Chemical/Ingredient]
type: Class
subclass of: Acids, Acyclic [Chemical/Ingredient]
subclass of: Fatty Acids, Volatile [Chemical/Ingredient]
Display_Name: Caproates
MeSH_CUI: M0003305
MeSH_DUI: D002208
MeSH_Name: Caproates
NUI: N0000008121
RxNorm_CUI: 1988
Synonym: Hexanoates
UMLS_CUI: C0006924
code: C26606
imported from: NDF-RT.owl

Carboxylic Acids [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Carboxylic Acids
MeSH_CUI: M0003405
MeSH_DUI: D002264
MeSH_Definition: Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
MeSH_Name: Carboxylic Acids
NUI: N0000008137
RxNorm_CUI: 2060
UMLS_CUI: C0007066
code: C26638
imported from: NDF-RT.owl

Cardanolides [Chemical/Ingredient]
type: Class
subclass of: Steroids [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cardanolides
MeSH_CUI: M0003447
MeSH_DUI: D002297
MeSH_Definition: The aglycone constituents of CARDIAC GLYCOSIDES. The ring structure is basically a cyclopentanoperhydrophenanthrene nucleus attached to a lactone ring at the C-17 position.
MeSH_Name: Cardanolides
NUI: N0000008140
RxNorm_CUI: 2077
UMLS_CUI: C0007142
code: C26644
imported from: NDF-RT.owl

Pyrans [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
Display_Name: Pyrans
MeSH_CUI: M0018220
MeSH_DUI: D011714
MeSH_Name: Pyrans
NUI: N0000008141
RxNorm_CUI: 8983
UMLS_CUI: C0034234
code: C26646
imported from: NDF-RT.owl

Coumarins [Chemical/Ingredient]
type: Class
subclass of: Benzopyrans [Chemical/Ingredient]
Display_Name: Coumarins
MeSH_CUI: M0005258
MeSH_DUI: D003374
MeSH_Definition: Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. The various coumarins have a wide range of proposed actions and uses including as ANTICOAGULANTS, pharmaceutical aids, indicators and reagents, photoreactive substances, and ANTINEOPLASTIC AGENTS.
MeSH_Name: Coumarins
NUI: N0000008142
RxNorm_CUI: 2899
Synonym: 1,2-Benzo-Pyrones
Synonym: 1,2-Benzopyrones
Synonym: Benzopyran-2-ones
Synonym: Coumarines
UMLS_CUI: C0010207
code: C26648
imported from: NDF-RT.owl

Benzylidene Compounds [Chemical/Ingredient]
type: Class
subclass of: Benzene Derivatives [Chemical/Ingredient]
Display_Name: Benzylidene Compounds
MeSH_CUI: M0002394
MeSH_DUI: D001597
MeSH_Definition: Compounds containing the PhCH= radical.
MeSH_Name: Benzylidene Compounds
NUI: N0000008143
RxNorm_CUI: 1432
UMLS_CUI: C0005107
code: C26650
imported from: NDF-RT.owl

Pyrimidine Nucleosides [Chemical/Ingredient]
type: Class
subclass of: Pyrimidines [Chemical/Ingredient]
subclass of: Nucleosides [Chemical/Ingredient]
Display_Name: Pyrimidine Nucleosides
MeSH_CUI: M0018258
MeSH_DUI: D011741
MeSH_Definition: Pyrimidines with a RIBOSE attached that can be phosphorylated to PYRIMIDINE NUCLEOTIDES.
MeSH_Name: Pyrimidine Nucleosides
NUI: N0000008147
RxNorm_CUI: 9013
UMLS_CUI: C0034287
code: C26658
imported from: NDF-RT.owl

Bridged Compounds [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Cyclic [Chemical/Ingredient]
subclass of: Polycyclic Compounds [Chemical/Ingredient]
Display_Name: Bridged Compounds
MeSH_CUI: M0002922
MeSH_DUI: D001952
MeSH_Definition: Cyclic hydrocarbons that contain multiple rings and share one or more atoms.
MeSH_Name: Bridged Compounds
NUI: N0000008149
RxNorm_CUI: 1740
UMLS_CUI: C0006174
code: C26662
imported from: NDF-RT.owl

Interferons [Chemical/Ingredient]
type: Class
subclass of: Cytokines [Chemical/Ingredient]
Display_Name: Interferons
MeSH_CUI: M0011491
MeSH_DUI: D007372
MeSH_Definition: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
MeSH_Name: Interferons
NUI: N0000008154
RxNorm_CUI: 5886
Synonym: Interferon
UMLS_CUI: C0021747
code: C26672
imported from: NDF-RT.owl

Cardiac Glycosides [Chemical/Ingredient]
type: Class
subclass of: Glycosides [Chemical/Ingredient]
subclass of: Cardanolides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cardiac Glycosides
MeSH_CUI: M0003451
MeSH_DUI: D002301
MeSH_Definition: Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
MeSH_Name: Cardiac Glycosides
NUI: N0000008157
RxNorm_CUI: 2079
Synonym: Cardiotonic Steroids
UMLS_CUI: C0007158
code: C26678
imported from: NDF-RT.owl

Polycyclic Hydrocarbons, Aromatic [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Aromatic [Chemical/Ingredient]
subclass of: Polycyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Polycyclic Hydrocarbons, Aromatic
MeSH_CUI: M0017164
MeSH_DUI: D011084
MeSH_Definition: A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
MeSH_Name: Polycyclic Hydrocarbons, Aromatic
NUI: N0000008164
RxNorm_CUI: 8504
Synonym: Polycyclic Aromatic Hydrocarbons
Synonym: Polynuclear Aromatic Hydrocarbons
UMLS_CUI: C0032458
code: C26692
imported from: NDF-RT.owl

Amines [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
Display_Name: Amines
MeSH_CUI: M0000913
MeSH_DUI: D000588
MeSH_Definition: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)
MeSH_Name: Amines
NUI: N0000008168
RxNorm_CUI: 823705
UMLS_CUI: C0002508
code: C26700
imported from: NDF-RT.owl

Bicyclo Compounds [Chemical/Ingredient]
type: Class
subclass of: Bridged Compounds [Chemical/Ingredient]
Display_Name: Bicyclo Compounds
MeSH_CUI: M0002469
MeSH_DUI: D001643
MeSH_Name: Bicyclo Compounds
NUI: N0000008171
RxNorm_CUI: 1530
UMLS_CUI: C0005378
code: C26706
imported from: NDF-RT.owl

Fatty Acids, Volatile [Chemical/Ingredient]
type: Class
subclass of: Fatty Acids [Chemical/Ingredient]
Display_Name: Fatty Acids, Volatile
MeSH_CUI: M0008273
MeSH_DUI: D005232
MeSH_Definition: Short-chain fatty acids of up to six carbon atoms in length. They are the major end products of microbial fermentation in the ruminant digestive tract and have also been implicated in the causation of neurological diseases in humans.
MeSH_Name: Fatty Acids, Volatile
NUI: N0000008176
RxNorm_CUI: 4303
Synonym: Fatty Acids, Short-Chain
UMLS_CUI: C0015691
code: C26716
imported from: NDF-RT.owl

Chlorobenzenes [Chemical/Ingredient]
type: Class
subclass of: Benzene Derivatives [Chemical/Ingredient]
subclass of: Hydrocarbons, Chlorinated [Chemical/Ingredient]
Display_Name: Chlorobenzenes
MeSH_CUI: M0004161
MeSH_DUI: D002722
MeSH_Name: Chlorobenzenes
NUI: N0000008177
RxNorm_CUI: 2376
UMLS_CUI: C0008230
code: C26718
imported from: NDF-RT.owl

Hypoxanthines [Chemical/Ingredient]
type: Class
subclass of: Purinones [Chemical/Ingredient]
Display_Name: Hypoxanthines
MeSH_CUI: M0010953
MeSH_DUI: D007042
MeSH_Definition: Purine bases related to hypoxanthine, an intermediate product of uric acid synthesis and a breakdown product of adenine catabolism.
MeSH_Name: Hypoxanthines
NUI: N0000008183
RxNorm_CUI: 5625
UMLS_CUI: C0020691
code: C26730
imported from: NDF-RT.owl

Glycoconjugates [Chemical/Ingredient]
type: Class
subclass of: Carbohydrates [Chemical/Ingredient]
Display_Name: Glycoconjugates
MeSH_CUI: M0009456
MeSH_DUI: D006001
MeSH_Definition: Carbohydrates covalently linked to a nonsugar moiety (lipids or proteins). The major glycoconjugates are glycoproteins, glycopeptides, peptidoglycans, glycolipids, and lipopolysaccharides. (From Biochemical Nomenclature and Related Documents, 2d ed; From Principles of Biochemistry, 2d ed)
MeSH_Name: Glycoconjugates
NUI: N0000008215
RxNorm_CUI: 4924
UMLS_CUI: C0017906
code: C26794
imported from: NDF-RT.owl

Azoles [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Azoles
MeSH_CUI: M0002083
MeSH_DUI: D001393
MeSH_Definition: Five membered rings containing a NITROGEN atom.
MeSH_Name: Azoles
NUI: N0000008217
RxNorm_CUI: 1269
UMLS_CUI: C0004504
code: C26798
imported from: NDF-RT.owl

Hydrocarbons, Alicyclic [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Cyclic [Chemical/Ingredient]
Display_Name: Hydrocarbons, Alicyclic
MeSH_CUI: M0010689
MeSH_DUI: D006840
MeSH_Definition: Organic compounds composed exclusively of carbon and hydrogen. Three or more carbon atoms are arranged in a cyclic structure and they possess aliphatic properties.
MeSH_Name: Hydrocarbons, Alicyclic
NUI: N0000008228
RxNorm_CUI: 5478
Synonym: Alicyclic Hydrocarbons
UMLS_CUI: C0020244
code: C26820
imported from: NDF-RT.owl

Hydrocarbons, Aromatic [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons, Cyclic [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Hydrocarbons, Aromatic
MeSH_CUI: M0010690
MeSH_DUI: D006841
MeSH_Definition: Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
MeSH_Name: Hydrocarbons, Aromatic
NUI: N0000008229
RxNorm_CUI: 5479
Synonym: Aromatic Hydrocarbons
UMLS_CUI: C0020245
code: C26822
imported from: NDF-RT.owl

Nucleosides [Chemical/Ingredient]
type: Class
subclass of: Glycosides [Chemical/Ingredient]
subclass of: Nucleic Acids, Nucleotides, and Nucleosides [Chemical/Ingredient]
Display_Name: Nucleosides
MeSH_CUI: M0015066
MeSH_DUI: D009705
MeSH_Definition: Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
MeSH_Name: Nucleosides
NUI: N0000008235
RxNorm_CUI: 7578
UMLS_CUI: C0028621
code: C26834
imported from: NDF-RT.owl

Pregnanes [Chemical/Ingredient]
type: Class
subclass of: Steroids [Chemical/Ingredient]
Display_Name: Pregnanes
MeSH_CUI: M0017507
MeSH_DUI: D011278
MeSH_Definition: Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms generally excreted in the urine.
MeSH_Name: Pregnanes
NUI: N0000008242
RxNorm_CUI: 8661
UMLS_CUI: C0033006
code: C26848
imported from: NDF-RT.owl

Sulfur Compounds [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
subclass of: Inorganic Chemicals [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Sulfur Compounds
MeSH_CUI: M0020800
MeSH_DUI: D013457
MeSH_Definition: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.
MeSH_Name: Sulfur Compounds
NUI: N0000008249
RxNorm_CUI: 10225
UMLS_CUI: C0038776
code: C26862
imported from: NDF-RT.owl

Purinones [Chemical/Ingredient]
type: Class
subclass of: Purines [Chemical/Ingredient]
Display_Name: Purinones
MeSH_CUI: M0018170
MeSH_DUI: D011688
MeSH_Name: Purinones
NUI: N0000008251
RxNorm_CUI: 8953
Synonym: Oxopurines
UMLS_CUI: C0034142
code: C26866
imported from: NDF-RT.owl

Inorganic Chemicals [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Inorganic Chemicals
MeSH_CUI: M0011365
MeSH_DUI: D007287
MeSH_Definition: A broad class of substances encompassing all those that do not include carbon and its derivatives as their principal elements. However, carbides, carbonates, cyanides, cyanates, and carbon disulfide are included in this class.
MeSH_Name: Inorganic Chemicals
NUI: N0000008257
RxNorm_CUI: 5824
UMLS_CUI: C0021521
code: C26878
imported from: NDF-RT.owl

Heterocyclic Compounds, Bridged-Ring [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
Display_Name: Heterocyclic Compounds, Bridged-Ring
MeSH_CUI: M0010291
MeSH_DUI: D006572
MeSH_Definition: A class of organic compounds which contain two rings that share a pair of bridgehead carbon atoms.
MeSH_Name: Heterocyclic Compounds, Bridged-Ring
NUI: N0000008258
RxNorm_CUI: 5288
Synonym: Bridged-Ring Heterocyclic Compounds
UMLS_CUI: C0019403
code: C26880
imported from: NDF-RT.owl

Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Heterocyclic Compounds, 1-Ring
MeSH_CUI: M0010292
MeSH_DUI: D006573
MeSH_Definition: A class of organic compounds containing a ring structure made up of more than one kind of atom, usually carbon plus another atom. The ring structure can be aromatic or nonaromatic.
MeSH_Name: Heterocyclic Compounds, 1-Ring
NUI: N0000008259
RxNorm_CUI: 5284
Synonym: Heterocyclic Cpds, 1-Ring
UMLS_CUI: C0019399
code: C26882
imported from: NDF-RT.owl

Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Heterocyclic Compounds, 2-Ring
MeSH_CUI: M0010293
MeSH_DUI: D006574
MeSH_Definition: A class of organic compounds containing two ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic.
MeSH_Name: Heterocyclic Compounds, 2-Ring
NUI: N0000008260
RxNorm_CUI: 5285
UMLS_CUI: C0019400
code: C26884
imported from: NDF-RT.owl

Heterocyclic Compounds with 4 or More Rings [Chemical/Ingredient]
type: Class
subclass of: Heterocyclic Compounds [Chemical/Ingredient]
Display_Name: Heterocyclic Compounds with 4 or More Rings
MeSH_CUI: M0010295
MeSH_DUI: D006576
MeSH_Definition: A class of organic compounds containing four or more ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic.
MeSH_Name: Heterocyclic Compounds with 4 or More Rings
NUI: N0000008261
RxNorm_CUI: 5287
Synonym: Heterocyclic Cpds, 4 or More Rings
UMLS_CUI: C0019402
code: C26886
imported from: NDF-RT.owl

Hydrocarbons, Cyclic [Chemical/Ingredient]
type: Class
subclass of: Hydrocarbons [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Hydrocarbons, Cyclic
MeSH_CUI: M0010694
MeSH_DUI: D006844
MeSH_Definition: Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.
MeSH_Name: Hydrocarbons, Cyclic
NUI: N0000008280
RxNorm_CUI: 5482
Synonym: Cyclic Hydrocarbons
UMLS_CUI: C0020248
code: C26926
imported from: NDF-RT.owl

Nucleic Acids, Nucleotides, and Nucleosides [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
Display_Name: Nucleic Acids, Nucleotides, and Nucleosides
MeSH_CUI: M0015067
MeSH_DUI: D009706
MeSH_Definition: Complex compounds of high molecular weight occurring in living cells. These are basically of two types, ribonucleic (RNA) and deoxyribonucleic (DNA) acids, both of which consist of nucleotides (nucleoside phosphates linked together by phosphate bridges).
MeSH_Name: Nucleic Acids, Nucleotides, and Nucleosides
NUI: N0000008282
RxNorm_CUI: 7579
UMLS_CUI: C0028622
code: C26930
imported from: NDF-RT.owl

Acetylcholine Activity Alteration [PE]
type: Class
subclass of: Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Display_Name: Acetylcholine Activity Alteration
NUI: N0000008290
RxNorm_CUI: 988978
UMLS_CUI: C1371273
code: C26946
imported from: NDF-RT.owl

Adrenal Cortical Activity Alteration [PE]
type: Class
subclass of: Endocrine Activity Alteration [PE]
Display_Name: Adrenal Cortical Activity Alteration
NUI: N0000008291
RxNorm_CUI: 985815
UMLS_CUI: C1371274
code: C26948
imported from: NDF-RT.owl

Breast Function Alteration [PE]
type: Class
subclass of: Female Reproductive System Activity Alteration [PE]
Display_Name: Breast Function Alteration
NUI: N0000008316
RxNorm_CUI: 990630
UMLS_CUI: C1371304
code: C26998
imported from: NDF-RT.owl

Breast Glandular Development Alteration [PE]
type: Class
subclass of: Breast Function Alteration [PE]
Display_Name: Breast Glandular Development Alteration
NUI: N0000008317
RxNorm_CUI: 989277
UMLS_CUI: C1371303
code: C27000
imported from: NDF-RT.owl

Carbohydrate Metabolism Alteration [PE]
type: Class
subclass of: Metabolic Activity Alteration [PE]
Display_Name: Carbohydrate Metabolism Alteration
NUI: N0000008327
RxNorm_CUI: 1033881
UMLS_CUI: C1371294
code: C27020
imported from: NDF-RT.owl

Cardiac Contractility Alteration [PE]
type: Class
subclass of: Cardiovascular Activity Alteration [PE]
Display_Name: Cardiac Contractility Alteration
NUI: N0000008328
RxNorm_CUI: 986415
UMLS_CUI: C1371293
code: C27022
imported from: NDF-RT.owl

Cardiac Rate Alteration [PE]
type: Class
subclass of: Cardiovascular Activity Alteration [PE]
Display_Name: Cardiac Rate Alteration
NUI: N0000008329
RxNorm_CUI: 985479
UMLS_CUI: C2825066
code: C27024
imported from: NDF-RT.owl

Cardiac Rhythm Alteration [PE]
type: Class
subclass of: Cardiovascular Activity Alteration [PE]
Display_Name: Cardiac Rhythm Alteration
NUI: N0000008330
RxNorm_CUI: 988420
UMLS_CUI: C1371292
code: C27026
imported from: NDF-RT.owl

Cardiovascular Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Cardiovascular Activity Alteration
NUI: N0000008331
RxNorm_CUI: 988145
UMLS_CUI: C1371291
code: C27028
imported from: NDF-RT.owl

Cell Membrane Alteration [PE]
type: Class
subclass of: Cellular Structure Alteration [PE]
Display_Name: Cell Membrane Alteration
NUI: N0000008334
RxNorm_CUI: 1031394
UMLS_CUI: C0544958
code: C27034
imported from: NDF-RT.owl

Cellular Activity Alteration [PE]
type: Class
subclass of: Generalized Systemic Effects [PE]
Display_Name: Cellular Activity Alteration
NUI: N0000008337
RxNorm_CUI: 985006
UMLS_CUI: C1371483
code: C27040
imported from: NDF-RT.owl

Cellular Cycle Alteration [PE]
type: Class
subclass of: Cellular Activity Alteration [PE]
Display_Name: Cellular Cycle Alteration
NUI: N0000008339
RxNorm_CUI: 990947
UMLS_CUI: C1371481
code: C27044
imported from: NDF-RT.owl

Cellular Degradation/Digestion Alteration [PE]
type: Class
subclass of: Cellular Activity Alteration [PE]
Display_Name: Cellular Degradation/Digestion Alteration
NUI: N0000008341
RxNorm_CUI: 990545
UMLS_CUI: C1371479
code: C27048
imported from: NDF-RT.owl

Cellular Growth Phase Alteration [PE]
type: Class
subclass of: Cellular Cycle Alteration [PE]
Display_Name: Cellular Growth Phase Alteration
NUI: N0000008343
RxNorm_CUI: 987428
UMLS_CUI: C1371477
code: C27052
imported from: NDF-RT.owl

Cellular Growth Phase Arrest [PE]
type: Class
subclass of: Cellular Growth Phase Reduction [PE]
Display_Name: Cellular Growth Phase Arrest
NUI: N0000008344
RxNorm_CUI: 986074
UMLS_CUI: C1371476
code: C27054
imported from: NDF-RT.owl

Cellular Motion Alteration [PE]
type: Class
subclass of: Cellular Activity Alteration [PE]
Display_Name: Cellular Motion Alteration
NUI: N0000008345
RxNorm_CUI: 988013
UMLS_CUI: C1371475
code: C27056
imported from: NDF-RT.owl

Cellular Structure Alteration [PE]
type: Class
subclass of: Cellular Activity Alteration [PE]
Display_Name: Cellular Structure Alteration
NUI: N0000008346
RxNorm_CUI: 990421
UMLS_CUI: C1371474
code: C27058
imported from: NDF-RT.owl

Cellular Synthetic Activity Alteration [PE]
type: Class
subclass of: Cellular Cycle Alteration [PE]
Display_Name: Cellular Synthetic Activity Alteration
NUI: N0000008347
RxNorm_CUI: 989470
UMLS_CUI: C1371473
code: C27060
imported from: NDF-RT.owl

Cellular Transport Alteration [PE]
type: Class
subclass of: Cellular Activity Alteration [PE]
Display_Name: Cellular Transport Alteration
NUI: N0000008350
RxNorm_CUI: 985278
UMLS_CUI: C1371312
code: C27066
imported from: NDF-RT.owl

Conduction System Depolarization [PE]
type: Class
subclass of: Cardiac Rhythm Alteration [PE]
type: NamedIndividual
Display_Name: Conduction System Depolarization
NUI: N0000008369
RxNorm_CUI: 985660
UMLS_CUI: C1371319
code: C27104
imported from: NDF-RT.owl

Connective Tissue Alteration [PE]
type: Class
subclass of: Musculoskeletal Activity Alteration [PE]
Display_Name: Connective Tissue Alteration
NUI: N0000008373
RxNorm_CUI: 987429
UMLS_CUI: C1371315
code: C27112
imported from: NDF-RT.owl

DNA Integrity Alteration [PE]
type: Class
subclass of: Nucleic Acid Replication Alteration [PE]
Display_Name: DNA Integrity Alteration
NUI: N0000008379
RxNorm_CUI: 984969
UMLS_CUI: C1371459
code: C27124
imported from: NDF-RT.owl

DNA Replication Alteration [PE]
type: Class
subclass of: Nucleic Acid Replication Alteration [PE]
Display_Name: DNA Replication Alteration
NUI: N0000008380
RxNorm_CUI: 985410
UMLS_CUI: C1371458
code: C27126
imported from: NDF-RT.owl

Decreased Acetylcholine Activity [PE]
type: Class
subclass of: Acetylcholine Activity Alteration [PE]
Display_Name: Decreased Acetylcholine Activity
NUI: N0000008383
RxNorm_CUI: 985411
UMLS_CUI: C1371330
code: C27132
imported from: NDF-RT.owl

Decreased Autonomic Nervous System Acetylcholine Activity [PE]
type: Class
subclass of: Decreased Peripheral Nervous System Acetylcholine Activity [PE]
Display_Name: Decreased Autonomic Nervous System Acetylcholine Activity
NUI: N0000008394
RxNorm_CUI: 985008
UMLS_CUI: C1371453
code: C27154
imported from: NDF-RT.owl

Decreased Autonomic Nervous System Norepinephrine Activity [PE]
type: Class
subclass of: Decreased Peripheral Nervous System Norepinephrine Activity [PE]
Display_Name: Decreased Autonomic Nervous System Norepinephrine Activity
NUI: N0000008412
RxNorm_CUI: 989573
UMLS_CUI: C2267191
code: C27190
imported from: NDF-RT.owl

Decreased Cell Membrane Integrity [PE]
type: Class
subclass of: Cell Membrane Alteration [PE]
Display_Name: Decreased Cell Membrane Integrity
NUI: N0000008476
RxNorm_CUI: 989770
UMLS_CUI: C1371353
code: C27318
imported from: NDF-RT.owl

Decreased Central Nervous System Dopamine Activity [PE]
type: Class
subclass of: Decreased Dopamine Activity [PE]
Display_Name: Decreased Central Nervous System Dopamine Activity
NUI: N0000008487
RxNorm_CUI: 990956
UMLS_CUI: C1371342
code: C27340
imported from: NDF-RT.owl

Decreased Central Nervous System Norepinephrine Activity [PE]
type: Class
subclass of: Decreased Norepinephrine Activity [PE]
Display_Name: Decreased Central Nervous System Norepinephrine Activity
NUI: N0000008500
RxNorm_CUI: 990153
UMLS_CUI: C2267194
code: C27366
imported from: NDF-RT.owl

Decreased Central Nervous System Organized Electrical Activity [PE]
type: Class
subclass of: Decreased Organized Electrical Activity [PE]
Display_Name: Decreased Central Nervous System Organized Electrical Activity
NUI: N0000008501
RxNorm_CUI: 987431
UMLS_CUI: C1371428
code: C27368
imported from: NDF-RT.owl

Decreased Cytokine Activity [PE]
type: Class
subclass of: Decreased Immunologically Active Molecule Activity [PE]
Display_Name: Decreased Cytokine Activity
NUI: N0000008571
RxNorm_CUI: 989703
UMLS_CUI: C1371548
code: C27508
imported from: NDF-RT.owl

Decreased Cytokine Production [PE]
type: Class
subclass of: Decreased Immunologically Active Molecule Production [PE]
Display_Name: Decreased Cytokine Production
NUI: N0000008573
RxNorm_CUI: 984977
UMLS_CUI: C1371550
code: C27512
imported from: NDF-RT.owl

Decreased DNA Integrity [PE]
type: Class
subclass of: DNA Integrity Alteration [PE]
Display_Name: Decreased DNA Integrity
NUI: N0000008576
RxNorm_CUI: 990547
UMLS_CUI: C1371553
code: C27518
imported from: NDF-RT.owl

Decreased DNA Replication [PE]
type: Class
subclass of: DNA Replication Alteration [PE]
Display_Name: Decreased DNA Replication
NUI: N0000008577
RxNorm_CUI: 989476
UMLS_CUI: C1371554
code: C27520
imported from: NDF-RT.owl

Decreased Disorganized Electrical Activity [PE]
type: Class
subclass of: Disorganized Electrical Activity Alteration [PE]
type: NamedIndividual
Display_Name: Decreased Disorganized Electrical Activity
NUI: N0000008578
RxNorm_CUI: 986372
UMLS_CUI: C1371555
code: C27522
imported from: NDF-RT.owl

Decreased Dopamine Activity [PE]
type: Class
subclass of: Dopamine Activity Alteration [PE]
Display_Name: Decreased Dopamine Activity
NUI: N0000008588
RxNorm_CUI: 988292
UMLS_CUI: C1371565
code: C27542
imported from: NDF-RT.owl

Decreased Eicosanoid Activity [PE]
type: Class
subclass of: Decreased Lipid Derived Immunologically Active Molecule Activity [PE]
Display_Name: Decreased Eicosanoid Activity
NUI: N0000008590
RxNorm_CUI: 984625
UMLS_CUI: C1371567
code: C27546
imported from: NDF-RT.owl

Decreased Endocytosis [PE]
type: Class
subclass of: Endocytosis Alteration [PE]
Display_Name: Decreased Endocytosis
NUI: N0000008596
RxNorm_CUI: 985823
UMLS_CUI: C1371573
code: C27558
imported from: NDF-RT.owl

Decreased GI Motility [PE]
type: Class
subclass of: GI Motility Alteration [PE]
Display_Name: Decreased GI Motility
NUI: N0000008635
RxNorm_CUI: 984546
UMLS_CUI: C1371645
code: C27636
imported from: NDF-RT.owl

Decreased Glucocorticoid Secretion [PE]
type: Class
subclass of: Adrenal Cortical Activity Alteration [PE]
Display_Name: Decreased Glucocorticoid Secretion
NUI: N0000008645
RxNorm_CUI: 988098
UMLS_CUI: C1371655
code: C27656
imported from: NDF-RT.owl

Decreased Hematopoiesis [PE]
type: Class
subclass of: Hematopoiesis Alteration [PE]
Display_Name: Decreased Hematopoiesis
NUI: N0000008656
RxNorm_CUI: 989826
UMLS_CUI: C2825067
code: C27678
imported from: NDF-RT.owl

Decreased Histamine Activity [PE]
type: Class
subclass of: Decreased Immunologically Active Biogenic Amine Activity [PE]
subclass of: Histamine Activity Alteration [PE]
Display_Name: Decreased Histamine Activity
NUI: N0000008657
RxNorm_CUI: 990635
UMLS_CUI: C1371666
code: C27680
imported from: NDF-RT.owl

Decreased Immunologically Active Biogenic Amine Activity [PE]
type: Class
subclass of: Decreased Immunologically Active Molecule Activity [PE]
Display_Name: Decreased Immunologically Active Biogenic Amine Activity
NUI: N0000008660
RxNorm_CUI: 986941
UMLS_CUI: C1371669
code: C27686
imported from: NDF-RT.owl

Decreased Immunologically Active Biogenic Amine Degradation [PE]
type: Class
subclass of: Decreased Immunologically Active Molecule Degradation [PE]
Display_Name: Decreased Immunologically Active Biogenic Amine Degradation
NUI: N0000008661
RxNorm_CUI: 986196
UMLS_CUI: C1371670
code: C27688
imported from: NDF-RT.owl

Decreased Immunologically Active Molecule Activity [PE]
type: Class
subclass of: Immunologically Active Molecule Activity Alteration [PE]
subclass of: Decreased Immunologic Activity [PE]
Display_Name: Decreased Immunologically Active Molecule Activity
NUI: N0000008663
RxNorm_CUI: 988758
UMLS_CUI: C1371672
code: C27692
imported from: NDF-RT.owl

Decreased Immunologically Active Molecule Degradation [PE]
type: Class
subclass of: Immunologically Active Molecule Degradation Alteration [PE]
subclass of: Decreased Immunologic Activity [PE]
Display_Name: Decreased Immunologically Active Molecule Degradation
NUI: N0000008664
RxNorm_CUI: 986197
UMLS_CUI: C1371673
code: C27694
imported from: NDF-RT.owl

Decreased Immunologically Active Molecule Production [PE]
type: Class
subclass of: Immunologically Active Molecule Production Alteration [PE]
subclass of: Decreased Immunologic Activity [PE]
Display_Name: Decreased Immunologically Active Molecule Production
NUI: N0000008665
RxNorm_CUI: 987036
UMLS_CUI: C1371674
code: C27696
imported from: NDF-RT.owl

Decreased Leukotriene Activity [PE]
type: Class
subclass of: Decreased Eicosanoid Activity [PE]
Display_Name: Decreased Leukotriene Activity
NUI: N0000008681
RxNorm_CUI: 987436
UMLS_CUI: C1371689
code: C27728
imported from: NDF-RT.owl

Decreased Lipid Derived Immunologically Active Molecule Activity [PE]
type: Class
subclass of: Decreased Immunologically Active Molecule Activity [PE]
Display_Name: Decreased Lipid Derived Immunologically Active Molecule Activity
NUI: N0000008684
RxNorm_CUI: 988099
UMLS_CUI: C1371692
code: C27734
imported from: NDF-RT.owl

Decreased Lymphocyte Cell Production [PE]
type: Class
subclass of: Decreased Hematopoiesis [PE]
Display_Name: Decreased Lymphocyte Cell Production
NUI: N0000008699
RxNorm_CUI: 990429
UMLS_CUI: C1371707
code: C27764
imported from: NDF-RT.owl

Decreased Metabolic Rate [PE]
type: Class
subclass of: Metabolic Rate Alteration [PE]
Display_Name: Decreased Metabolic Rate
NUI: N0000008707
RxNorm_CUI: 989776
UMLS_CUI: C1371715
code: C27780
imported from: NDF-RT.owl

Decreased Norepinephrine Activity [PE]
type: Class
subclass of: Norepinephrine Activity Alteration [PE]
type: NamedIndividual
Display_Name: Decreased Norepinephrine Activity
NUI: N0000008764
RxNorm_CUI: 989127
UMLS_CUI: C2267200
code: C27894
imported from: NDF-RT.owl

Decreased Organized Electrical Activity [PE]
type: Class
subclass of: Organized Electrical Activity Alteration [PE]
Display_Name: Decreased Organized Electrical Activity
NUI: N0000008768
RxNorm_CUI: 987290
UMLS_CUI: C1371776
code: C27902
imported from: NDF-RT.owl

Decreased Ovarian Estrogen Secretion [PE]
type: Class
subclass of: Ovarian Endocrine Activity Alteration [PE]
Display_Name: Decreased Ovarian Estrogen Secretion
NUI: N0000008769
RxNorm_CUI: 985018
UMLS_CUI: C1371777
code: C27904
imported from: NDF-RT.owl

Decreased Parasympathetic Acetylcholine Activity [PE]
type: Class
subclass of: Decreased Autonomic Nervous System Acetylcholine Activity [PE]
subclass of: Decreased Parasympathetic Activity [PE]
Display_Name: Decreased Parasympathetic Acetylcholine Activity
NUI: N0000008779
RxNorm_CUI: 985834
UMLS_CUI: C1371787
code: C27924
imported from: NDF-RT.owl

Decreased Peripheral Nervous System Acetylcholine Activity [PE]
type: Class
subclass of: Decreased Acetylcholine Activity [PE]
Display_Name: Decreased Peripheral Nervous System Acetylcholine Activity
NUI: N0000008802
RxNorm_CUI: 985671
UMLS_CUI: C1371810
code: C27970
imported from: NDF-RT.owl

Decreased Peripheral Nervous System Norepinephrine Activity [PE]
type: Class
subclass of: Decreased Norepinephrine Activity [PE]
Display_Name: Decreased Peripheral Nervous System Norepinephrine Activity
NUI: N0000008820
RxNorm_CUI: 987038
UMLS_CUI: C2267202
code: C28006
imported from: NDF-RT.owl

Decreased Prostaglandin Activity [PE]
type: Class
subclass of: Decreased Eicosanoid Activity [PE]
Display_Name: Decreased Prostaglandin Activity
NUI: N0000008834
RxNorm_CUI: 984465
UMLS_CUI: C1371841
code: C28034
imported from: NDF-RT.owl

Decreased Protein Synthesis [PE]
type: Class
subclass of: Striated Muscle Anabolism Alteration [PE]
subclass of: Translation Alteration [PE]
Display_Name: Decreased Protein Synthesis
NUI: N0000008841
RxNorm_CUI: 987293
UMLS_CUI: C1371848
code: C28048
imported from: NDF-RT.owl

Decreased RNA Replication [PE]
type: Class
subclass of: RNA Replication Alteration [PE]
Display_Name: Decreased RNA Replication
NUI: N0000008853
RxNorm_CUI: 985312
UMLS_CUI: C1371860
code: C28072
imported from: NDF-RT.owl

Decreased Respiratory Secretions [PE]
type: Class
subclass of: Respiratory Secretion Alteration [PE]
type: NamedIndividual
Display_Name: Decreased Respiratory Secretions
NUI: N0000008868
RxNorm_CUI: 985021
UMLS_CUI: C1371875
code: C28102
imported from: NDF-RT.owl

Decreased Serotonin Activity [PE]
type: Class
subclass of: Decreased Immunologically Active Biogenic Amine Activity [PE]
subclass of: Serotonin Activity Alteration [PE]
Display_Name: Decreased Serotonin Activity
NUI: N0000008893
RxNorm_CUI: 990122
UMLS_CUI: C1371900
code: C28152
imported from: NDF-RT.owl

Decreased Serotonin Degradation [PE]
type: Class
subclass of: Decreased Immunologically Active Biogenic Amine Degradation [PE]
Display_Name: Decreased Serotonin Degradation
NUI: N0000008894
RxNorm_CUI: 989582
UMLS_CUI: C1371901
code: C28154
imported from: NDF-RT.owl

Decreased Sympathetic Norepinephrine Activity [PE]
type: Class
subclass of: Decreased Autonomic Nervous System Norepinephrine Activity [PE]
subclass of: Decreased Sympathetic Activity [PE]
type: NamedIndividual
Display_Name: Decreased Sympathetic Norepinephrine Activity
NUI: N0000008992
RxNorm_CUI: 986379
UMLS_CUI: C2267207
code: C28350
imported from: NDF-RT.owl

Decreased T Lymphocyte Production [PE]
type: Class
subclass of: Decreased Lymphocyte Cell Production [PE]
Display_Name: Decreased T Lymphocyte Production
NUI: N0000008998
RxNorm_CUI: 986572
UMLS_CUI: C1372004
code: C28362
imported from: NDF-RT.owl

Decreased Thromboxane Activity [PE]
type: Class
subclass of: Decreased Eicosanoid Activity [PE]
Display_Name: Decreased Thromboxane Activity
NUI: N0000009004
RxNorm_CUI: 986734
UMLS_CUI: C1372010
code: C28374
imported from: NDF-RT.owl

Decreased Uterine Smooth Muscle Contraction or Tone [PE]
type: Class
subclass of: Uterine Smooth Muscle Contraction or Tone [PE]
Display_Name: Decreased Uterine Smooth Muscle Contraction or Tone
NUI: N0000009014
RxNorm_CUI: 987238
UMLS_CUI: C1372020
code: C28394
imported from: NDF-RT.owl

Digestive/GI System Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Digestive/GI System Activity Alteration
NUI: N0000009022
RxNorm_CUI: 990045
UMLS_CUI: C1372028
code: C28410
imported from: NDF-RT.owl

Disorganized Electrical Activity Alteration [PE]
type: Class
subclass of: Electrical Activity Alteration [PE]
Display_Name: Disorganized Electrical Activity Alteration
NUI: N0000009024
RxNorm_CUI: 987926
UMLS_CUI: C1372030
code: C28414
imported from: NDF-RT.owl

Dopamine Activity Alteration [PE]
type: Class
subclass of: Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Display_Name: Dopamine Activity Alteration
NUI: N0000009025
RxNorm_CUI: 986437
UMLS_CUI: C1372031
code: C28416
imported from: NDF-RT.owl

Electrical Activity Alteration [PE]
type: Class
subclass of: Nervous System Activity Alteration [PE]
type: NamedIndividual
Display_Name: Electrical Activity Alteration
NUI: N0000009027
RxNorm_CUI: 985119
UMLS_CUI: C1372033
code: C28420
imported from: NDF-RT.owl

Emesis Suppression [PE]
type: Class
subclass of: Decreased GI Motility [PE]
subclass of: Central Nervous System Depression [PE]
Display_Name: Emesis Suppression
NUI: N0000009034
RxNorm_CUI: 987062
UMLS_CUI: C1372039
code: C28434
imported from: NDF-RT.owl

Endocrine Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Endocrine Activity Alteration
NUI: N0000009036
RxNorm_CUI: 990694
UMLS_CUI: C1372041
code: C28438
imported from: NDF-RT.owl

Endocytosis Alteration [PE]
type: Class
subclass of: Cellular Transport Alteration [PE]
Display_Name: Endocytosis Alteration
NUI: N0000009037
RxNorm_CUI: 990695
UMLS_CUI: C1372042
code: C28440
imported from: NDF-RT.owl

Female Reproductive System Activity Alteration [PE]
type: Class
subclass of: Reproductive System Activity Alteration [PE]
Display_Name: Female Reproductive System Activity Alteration
NUI: N0000009044
RxNorm_CUI: 985744
UMLS_CUI: C1372049
code: C28454
imported from: NDF-RT.owl

GI Motility Alteration [PE]
type: Class
subclass of: Digestive/GI System Activity Alteration [PE]
Display_Name: GI Motility Alteration
NUI: N0000009048
RxNorm_CUI: 990046
UMLS_CUI: C1372053
code: C28462
imported from: NDF-RT.owl

Generalized Systemic Effects [PE]
type: Class
subclass of: Physiological Effects [PE]
Display_Name: Generalized Systemic Effects
NUI: N0000009057
RxNorm_CUI: 990172
UMLS_CUI: C1372062
code: C28480
imported from: NDF-RT.owl

Hematologic Activity Alteration [PE]
type: Class
subclass of: Hemic/Lymphatic Activity Alteration [PE]
Display_Name: Hematologic Activity Alteration
NUI: N0000009065
RxNorm_CUI: 986633
UMLS_CUI: C1372069
code: C28496
imported from: NDF-RT.owl

Hematological Cell Destruction Alteration [PE]
type: Class
subclass of: Hematological Cell Quantity Alteration [PE]
Display_Name: Hematological Cell Destruction Alteration
NUI: N0000009066
RxNorm_CUI: 987239
UMLS_CUI: C1372070
code: C28498
imported from: NDF-RT.owl

Hematological Cell Quantity Alteration [PE]
type: Class
subclass of: Hematologic Activity Alteration [PE]
Display_Name: Hematological Cell Quantity Alteration
NUI: N0000009067
RxNorm_CUI: 989409
UMLS_CUI: C1372071
code: C28500
imported from: NDF-RT.owl

Hematopoiesis Alteration [PE]
type: Class
subclass of: Hematological Cell Quantity Alteration [PE]
Display_Name: Hematopoiesis Alteration
NUI: N0000009068
RxNorm_CUI: 988943
UMLS_CUI: C1372072
code: C28502
imported from: NDF-RT.owl

Hemic/Lymphatic Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Hemic/Lymphatic Activity Alteration
NUI: N0000009069
RxNorm_CUI: 990696
UMLS_CUI: C1372073
code: C28504
imported from: NDF-RT.owl

Histamine Activity Alteration [PE]
type: Class
subclass of: Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Display_Name: Histamine Activity Alteration
NUI: N0000009071
RxNorm_CUI: 989587
UMLS_CUI: C1372075
code: C28508
imported from: NDF-RT.owl

Hypothalamic Endocrine Activity Alteration [PE]
type: Class
subclass of: Endocrine Activity Alteration [PE]
Display_Name: Hypothalamic Endocrine Activity Alteration
NUI: N0000009072
RxNorm_CUI: 989001
UMLS_CUI: C1372076
code: C28510
imported from: NDF-RT.owl

Immunologic Activity Alteration [PE]
type: Class
subclass of: Generalized Systemic Effects [PE]
Display_Name: Immunologic Activity Alteration
NUI: N0000009073
RxNorm_CUI: 990814
UMLS_CUI: C1372077
code: C28512
imported from: NDF-RT.owl

Immunologically Active Molecule Activity Alteration [PE]
type: Class
subclass of: Immunologic Activity Alteration [PE]
Display_Name: Immunologically Active Molecule Activity Alteration
NUI: N0000009074
RxNorm_CUI: 985286
UMLS_CUI: C1372078
code: C28514
imported from: NDF-RT.owl

Immunologically Active Molecule Degradation Alteration [PE]
type: Class
subclass of: Immunologic Activity Alteration [PE]
Display_Name: Immunologically Active Molecule Degradation Alteration
NUI: N0000009075
RxNorm_CUI: 989847
UMLS_CUI: C1372079
code: C28516
imported from: NDF-RT.owl

Immunologically Active Molecule Production Alteration [PE]
type: Class
subclass of: Immunologic Activity Alteration [PE]
Display_Name: Immunologically Active Molecule Production Alteration
NUI: N0000009076
RxNorm_CUI: 989133
UMLS_CUI: C1372080
code: C28518
imported from: NDF-RT.owl

Increased Central Nervous System Norepinephrine Activity [PE]
type: Class
subclass of: Increased Norepinephrine Activity [PE]
Display_Name: Increased Central Nervous System Norepinephrine Activity
NUI: N0000009196
RxNorm_CUI: 990469
UMLS_CUI: C1372200
code: C28758
imported from: NDF-RT.owl

Increased Cytokine Activity [PE]
type: Class
subclass of: Increased Immunologically Active Molecule Activity [PE]
Display_Name: Increased Cytokine Activity
NUI: N0000009267
RxNorm_CUI: 984447
UMLS_CUI: C1372271
code: C28900
imported from: NDF-RT.owl

Increased Hematological Cell Destruction [PE]
type: Class
subclass of: Hematological Cell Destruction Alteration [PE]
Display_Name: Increased Hematological Cell Destruction
NUI: N0000009349
RxNorm_CUI: 985291
UMLS_CUI: C1372350
code: C29064
imported from: NDF-RT.owl

Increased Immunologically Active Molecule Activity [PE]
type: Class
subclass of: Immunologically Active Molecule Activity Alteration [PE]
subclass of: Increased Immunologic Activity [PE]
Display_Name: Increased Immunologically Active Molecule Activity
NUI: N0000009357
RxNorm_CUI: 989011
UMLS_CUI: C1372357
code: C29080
imported from: NDF-RT.owl

Increased Lymphocyte Cell Destruction [PE]
type: Class
subclass of: Increased Hematological Cell Destruction [PE]
Display_Name: Increased Lymphocyte Cell Destruction
NUI: N0000009390
RxNorm_CUI: 985905
UMLS_CUI: C1372389
code: C29146
imported from: NDF-RT.owl

Increased Norepinephrine Activity [PE]
type: Class
subclass of: Norepinephrine Activity Alteration [PE]
Display_Name: Increased Norepinephrine Activity
NUI: N0000009456
RxNorm_CUI: 985294
UMLS_CUI: C1372455
code: C29278
imported from: NDF-RT.owl

Increased T Lymphocyte Destruction [PE]
type: Class
subclass of: Increased Lymphocyte Cell Destruction [PE]
Display_Name: Increased T Lymphocyte Destruction
NUI: N0000009689
RxNorm_CUI: 990657
UMLS_CUI: C1372687
code: C29744
imported from: NDF-RT.owl

Inhibit Ovarian Follicular Phase [PE]
type: Class
subclass of: Ovarian Follicular Phase Alteration [PE]
Display_Name: Inhibit Ovarian Follicular Phase
NUI: N0000009715
RxNorm_CUI: 985705
UMLS_CUI: C1372713
code: C29796
imported from: NDF-RT.owl

Inhibit Ovulation [PE]
type: Class
subclass of: Ovulation Alteration [PE]
Display_Name: Inhibit Ovulation
NUI: N0000009717
RxNorm_CUI: 986227
UMLS_CUI: C0542129
code: C29800
imported from: NDF-RT.owl

Large Intestine Fluid/Electrolyte Absorption Alteration [PE]
type: Class
subclass of: Large Intestine Fluid/Electrolyte Alteration [PE]
Display_Name: Large Intestine Fluid/Electrolyte Absorption Alteration
NUI: N0000009736
RxNorm_CUI: 986030
UMLS_CUI: C1372733
code: C29838
imported from: NDF-RT.owl

Large Intestine Fluid/Electrolyte Alteration [PE]
type: Class
subclass of: Digestive/GI System Activity Alteration [PE]
Display_Name: Large Intestine Fluid/Electrolyte Alteration
NUI: N0000009737
RxNorm_CUI: 988364
UMLS_CUI: C1372734
code: C29840
imported from: NDF-RT.owl

Lipid Metabolism Alteration [PE]
type: Class
subclass of: Metabolic Activity Alteration [PE]
type: NamedIndividual
Display_Name: Lipid Metabolism Alteration
NUI: N0000009739
RxNorm_CUI: 987514
UMLS_CUI: C0548934
code: C29844
imported from: NDF-RT.owl

Lysosomal Function Alteration [PE]
type: Class
subclass of: Cellular Degradation/Digestion Alteration [PE]
Display_Name: Lysosomal Function Alteration
NUI: N0000009741
RxNorm_CUI: 988749
UMLS_CUI: C1372737
code: C29848
imported from: NDF-RT.owl

Metabolic Activity Alteration [PE]
type: Class
subclass of: Generalized Systemic Effects [PE]
Display_Name: Metabolic Activity Alteration
NUI: N0000009748
RxNorm_CUI: 990190
UMLS_CUI: C1372744
code: C29862
imported from: NDF-RT.owl

Metabolic Rate Alteration [PE]
type: Class
subclass of: Metabolic Activity Alteration [PE]
Display_Name: Metabolic Rate Alteration
NUI: N0000009749
RxNorm_CUI: 986653
UMLS_CUI: C1372745
code: C29864
imported from: NDF-RT.owl

Musculoskeletal Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Musculoskeletal Activity Alteration
NUI: N0000009755
RxNorm_CUI: 985711
UMLS_CUI: C1372751
code: C29876
imported from: NDF-RT.owl

Negative Chronotropy [PE]
type: Class
subclass of: Cardiac Rate Alteration [PE]
type: NamedIndividual
Display_Name: Negative Chronotropy
NUI: N0000009756
RxNorm_CUI: 986396
UMLS_CUI: C1372752
code: C29878
imported from: NDF-RT.owl

Nervous System Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
type: NamedIndividual
Display_Name: Nervous System Activity Alteration
NUI: N0000009759
RxNorm_CUI: 987311
UMLS_CUI: C2916815
code: C29884
imported from: NDF-RT.owl

Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
type: Class
subclass of: Nervous System Activity Alteration [PE]
Display_Name: Neurotransmitter & Neuromuscular Transmitter Activity Alteration
NUI: N0000009761
RxNorm_CUI: 989639
UMLS_CUI: C1372757
code: C29888
imported from: NDF-RT.owl

Nodal Depolarization [PE]
type: Class
subclass of: Cardiac Rhythm Alteration [PE]
type: NamedIndividual
Display_Name: Nodal Depolarization
NUI: N0000009763
RxNorm_CUI: 987463
UMLS_CUI: C1372759
code: C29892
imported from: NDF-RT.owl

Norepinephrine Activity Alteration [PE]
type: Class
subclass of: Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Display_Name: Norepinephrine Activity Alteration
NUI: N0000009765
RxNorm_CUI: 985713
UMLS_CUI: C1372761
code: C29896
imported from: NDF-RT.owl

Nucleic Acid Replication Alteration [PE]
type: Class
subclass of: Cellular Synthetic Activity Alteration [PE]
Display_Name: Nucleic Acid Replication Alteration
NUI: N0000009766
RxNorm_CUI: 989424
UMLS_CUI: C1372762
code: C29898
imported from: NDF-RT.owl

Ocular Smooth Muscle Activity Alteration [PE]
type: Class
subclass of: Special Sensory Systems Activity Alteration [PE]
Display_Name: Ocular Smooth Muscle Activity Alteration
NUI: N0000009768
RxNorm_CUI: 988502
UMLS_CUI: C1372764
code: C29902
imported from: NDF-RT.owl

Organ System Specific Effects [PE]
type: Class
subclass of: Physiological Effects [PE]
Display_Name: Organ System Specific Effects
NUI: N0000009770
RxNorm_CUI: 985923
UMLS_CUI: C1372766
code: C29906
imported from: NDF-RT.owl

Organized Electrical Activity Alteration [PE]
type: Class
subclass of: Electrical Activity Alteration [PE]
Display_Name: Organized Electrical Activity Alteration
NUI: N0000009774
RxNorm_CUI: 988792
UMLS_CUI: C1372770
code: C29914
imported from: NDF-RT.owl

Ovarian Endocrine Activity Alteration [PE]
type: Class
subclass of: Endocrine Activity Alteration [PE]
Display_Name: Ovarian Endocrine Activity Alteration
NUI: N0000009777
RxNorm_CUI: 985043
UMLS_CUI: C1372773
code: C29920
imported from: NDF-RT.owl

Ovarian Follicular Phase Alteration [PE]
type: Class
subclass of: Ovarian Function Alteration [PE]
Display_Name: Ovarian Follicular Phase Alteration
NUI: N0000009778
RxNorm_CUI: 986186
UMLS_CUI: C1372774
code: C29922
imported from: NDF-RT.owl

Ovarian Function Alteration [PE]
type: Class
subclass of: Female Reproductive System Activity Alteration [PE]
Display_Name: Ovarian Function Alteration
NUI: N0000009779
RxNorm_CUI: 986398
UMLS_CUI: C1372775
code: C29924
imported from: NDF-RT.owl

Ovulation Alteration [PE]
type: Class
subclass of: Ovarian Function Alteration [PE]
Display_Name: Ovulation Alteration
NUI: N0000009781
RxNorm_CUI: 990274
UMLS_CUI: C1372777
code: C29928
imported from: NDF-RT.owl

Physiological Effects [PE]
type: Class
subclass of: process
type: NamedIndividual
Display_Name: Physiological Effects
NUI: N0000009802
RxNorm_CUI: 984490
UMLS_CUI: C1372798
code: C29970
imported from: NDF-RT.owl

Positive Chronotropy [PE]
type: Class
subclass of: Cardiac Rate Alteration [PE]
type: NamedIndividual
Display_Name: Positive Chronotropy
NUI: N0000009808
RxNorm_CUI: 987259
UMLS_CUI: C1372804
code: C29982
imported from: NDF-RT.owl

Positive Inotropy [PE]
type: Class
subclass of: Cardiac Contractility Alteration [PE]
type: NamedIndividual
Display_Name: Positive Inotropy
NUI: N0000009809
RxNorm_CUI: 989869
UMLS_CUI: C1372805
code: C29984
imported from: NDF-RT.owl

Pupillary Dilation [PE]
type: Class
subclass of: Ocular Smooth Muscle Activity Alteration [PE]
Display_Name: Pupillary Dilation
NUI: N0000009820
RxNorm_CUI: 989596
UMLS_CUI: C1383072
code: C30006
imported from: NDF-RT.owl

RNA Replication Alteration [PE]
type: Class
subclass of: Nucleic Acid Replication Alteration [PE]
Display_Name: RNA Replication Alteration
NUI: N0000009822
RxNorm_CUI: 985505
UMLS_CUI: C1372853
code: C30010
imported from: NDF-RT.owl

Renal/Urological Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
type: NamedIndividual
Display_Name: Renal/Urological Activity Alteration
NUI: N0000009832
RxNorm_CUI: 988191
UMLS_CUI: C1372863
code: C30030
imported from: NDF-RT.owl

Reproductive System Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Reproductive System Activity Alteration
NUI: N0000009833
RxNorm_CUI: 990488
UMLS_CUI: C1372864
code: C30032
imported from: NDF-RT.owl

Respiratory Secretion Alteration [PE]
type: Class
subclass of: Respiratory/Pulmonary Activity Alteration [PE]
Display_Name: Respiratory Secretion Alteration
NUI: N0000009836
RxNorm_CUI: 984707
UMLS_CUI: C1372867
code: C30038
imported from: NDF-RT.owl

Respiratory/Pulmonary Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Respiratory/Pulmonary Activity Alteration
NUI: N0000009839
RxNorm_CUI: 987910
UMLS_CUI: C1372870
code: C30044
imported from: NDF-RT.owl

Saliva Production Alteration [PE]
type: Class
subclass of: Digestive/GI System Activity Alteration [PE]
Display_Name: Saliva Production Alteration
NUI: N0000009841
RxNorm_CUI: 986450
UMLS_CUI: C1372872
code: C30048
imported from: NDF-RT.owl

Salivation Inhibition [PE]
type: Class
subclass of: Saliva Production Alteration [PE]
Display_Name: Salivation Inhibition
NUI: N0000009842
RxNorm_CUI: 989642
UMLS_CUI: C1372873
code: C30050
imported from: NDF-RT.owl

Serotonin Activity Alteration [PE]
type: Class
subclass of: Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Display_Name: Serotonin Activity Alteration
NUI: N0000009844
RxNorm_CUI: 986797
UMLS_CUI: C1372875
code: C30054
imported from: NDF-RT.owl

Small Intestine Fluid/Electrolyte Absorption Alteration [PE]
type: Class
subclass of: Small Intestine Fluid/Electrolyte Alteration [PE]
Display_Name: Small Intestine Fluid/Electrolyte Absorption Alteration
NUI: N0000009845
RxNorm_CUI: 985050
UMLS_CUI: C1372876
code: C30056
imported from: NDF-RT.owl

Small Intestine Fluid/Electrolyte Alteration [PE]
type: Class
subclass of: Digestive/GI System Activity Alteration [PE]
Display_Name: Small Intestine Fluid/Electrolyte Alteration
NUI: N0000009846
RxNorm_CUI: 988322
UMLS_CUI: C1372877
code: C30058
imported from: NDF-RT.owl

Special Sensory Systems Activity Alteration [PE]
type: Class
subclass of: Organ System Specific Effects [PE]
Display_Name: Special Sensory Systems Activity Alteration
NUI: N0000009851
RxNorm_CUI: 990845
UMLS_CUI: C1372882
code: C30068
imported from: NDF-RT.owl

Stimulate Breast Glandular Development [PE]
type: Class
subclass of: Breast Glandular Development Alteration [PE]
Display_Name: Stimulate Breast Glandular Development
NUI: N0000009857
RxNorm_CUI: 985051
UMLS_CUI: C1372888
code: C30080
imported from: NDF-RT.owl

Stimulate Ovulation [PE]
type: Class
subclass of: Ovulation Alteration [PE]
Display_Name: Stimulate Ovulation
NUI: N0000009863
RxNorm_CUI: 988583
UMLS_CUI: C1372894
code: C30092
imported from: NDF-RT.owl

Stimulate Uterine Secretory Phase [PE]
type: Class
subclass of: Uterine Secretory Phase Alteration [PE]
Display_Name: Stimulate Uterine Secretory Phase
NUI: N0000009867
RxNorm_CUI: 986656
UMLS_CUI: C1372898
code: C30100
imported from: NDF-RT.owl

Stimulation Large Intestine Fluid/Electrolyte Absorption [PE]
type: Class
subclass of: Large Intestine Fluid/Electrolyte Absorption Alteration [PE]
Display_Name: Stimulation Large Intestine Fluid/Electrolyte Absorption
NUI: N0000009870
RxNorm_CUI: 988965
UMLS_CUI: C1372901
code: C30106
imported from: NDF-RT.owl

Stimulation Small Intestine Fluid/Electrolyte Absorption [PE]
type: Class
subclass of: Small Intestine Fluid/Electrolyte Absorption Alteration [PE]
Display_Name: Stimulation Small Intestine Fluid/Electrolyte Absorption
NUI: N0000009874
RxNorm_CUI: 989426
UMLS_CUI: C1372905
code: C30114
imported from: NDF-RT.owl

Striated Muscle Metabolic Alteration [PE]
type: Class
subclass of: Musculoskeletal Activity Alteration [PE]
Display_Name: Striated Muscle Metabolic Alteration
NUI: N0000009876
RxNorm_CUI: 984454
UMLS_CUI: C2916793
code: C30118
imported from: NDF-RT.owl

Striated Muscle Anabolism Alteration [PE]
type: Class
subclass of: Striated Muscle Metabolic Alteration [PE]
Display_Name: Striated Muscle Anabolism Alteration
NUI: N0000009877
RxNorm_CUI: 989427
UMLS_CUI: C1372908
code: C30120
imported from: NDF-RT.owl

Translation Alteration [PE]
type: Class
subclass of: Cellular Synthetic Activity Alteration [PE]
Display_Name: Translation Alteration
NUI: N0000009894
RxNorm_CUI: 984492
UMLS_CUI: C1372925
code: C30154
imported from: NDF-RT.owl

Uterine Function Alteration [PE]
type: Class
subclass of: Female Reproductive System Activity Alteration [PE]
Display_Name: Uterine Function Alteration
NUI: N0000009897
RxNorm_CUI: 1030550
UMLS_CUI: C1372928
code: C30160
imported from: NDF-RT.owl

Uterine Secretory Phase Alteration [PE]
type: Class
subclass of: Uterine Function Alteration [PE]
Display_Name: Uterine Secretory Phase Alteration
NUI: N0000009900
RxNorm_CUI: 988125
UMLS_CUI: C1372931
code: C30166
imported from: NDF-RT.owl

Uterine Smooth Muscle Contraction or Tone [PE]
type: Class
subclass of: Uterine Function Alteration [PE]
subclass of: Smooth Muscle Tone Alteration [PE]
Display_Name: Uterine Smooth Muscle Contraction or Tone
NUI: N0000009901
RxNorm_CUI: 989645
UMLS_CUI: C1372932
code: C30168
imported from: NDF-RT.owl

Unknown Cellular or Molecular Interaction [MoA]
type: Class
subclass of: Cellular or Molecular Interactions [MoA]
type: NamedIndividual
Display_Name: Unknown Cellular or Molecular Interaction
NUI: N0000009915
RxNorm_CUI: 990716
UMLS_CUI: C1373108
code: C30196
imported from: NDF-RT.owl

Decreased Cellular Migration [PE]
type: Class
subclass of: Cellular Motion Alteration [PE]
Display_Name: Decreased Cellular Migration
NUI: N0000009928
RxNorm_CUI: 989196
UMLS_CUI: C1372848
code: C30224
imported from: NDF-RT.owl

nitazoxanide [Chemical/Ingredient]
type: Class
subclass of: Thiazoles [Chemical/Ingredient]
Display_Name: nitazoxanide
MeSH_CUI: M0123653
MeSH_DUI: C041747
MeSH_Name: nitazoxanide
NUI: N0000010148
RxNorm_CUI: 31819
RxNorm_Name: nitazoxanide
Synonym: 2-(Acetolyloxy)-N-(5-nitro-2-thiazolyl)benzamide
UMLS_CUI: C0068788
code: C31486
imported from: NDF-RT.owl

Pregnancy [Disease/Finding]
type: Class
subclass of: Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Pregnancy
NUI: N0000010195
RxNorm_CUI: 1022794
SNOMED_CID: 289908002
UMLS_CUI: C0032961
code: C31746
imported from: NDF-RT.owl

Physiologic States [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Physiologic States
NUI: N0000010197
RxNorm_CUI: 989040
UMLS_CUI: C2916830
code: C31750
imported from: NDF-RT.owl

Demographic States [Disease/Finding]
type: Class
subclass of: Diseases, Manifestations or Physiologic States [Disease/Finding]
Display_Name: Demographic States
NUI: N0000010198
RxNorm_CUI: 985726
UMLS_CUI: C2916805
code: C31754
imported from: NDF-RT.owl

Age Categories [Disease/Finding]
type: Class
subclass of: Demographic States [Disease/Finding]
Display_Name: Age Categories
NUI: N0000010202
RxNorm_CUI: 989345
UMLS_CUI: C2916832
code: C31762
imported from: NDF-RT.owl

Infant [Disease/Finding]
type: Class
subclass of: Age Categories [Disease/Finding]
type: NamedIndividual
Display_Name: Infant
NUI: N0000010203
RxNorm_CUI: 1023674
SNOMED_CID: 133931009
UMLS_CUI: C0021270
code: C31764
imported from: NDF-RT.owl

Child [Disease/Finding]
type: Class
subclass of: Age Categories [Disease/Finding]
type: NamedIndividual
Display_Name: Child
NUI: N0000010205
RxNorm_CUI: 1025000
SNOMED_CID: 410601007
UMLS_CUI: C0008059
code: C31768
imported from: NDF-RT.owl

Young Child [Disease/Finding]
type: Class
subclass of: Child [Disease/Finding]
type: NamedIndividual
Display_Name: Young Child
NUI: N0000010207
RxNorm_CUI: 1029003
SNOMED_CID: 74489007
UMLS_CUI: C0728836
code: C31772
imported from: NDF-RT.owl

Lactation [Disease/Finding]
type: Class
subclass of: Physiologic States [Disease/Finding]
type: NamedIndividual
Display_Name: Lactation
NUI: N0000010216
RxNorm_CUI: 1025167
SNOMED_CID: 169741004
UMLS_CUI: C0022925
code: C31790
imported from: NDF-RT.owl

Decreased Polymorphonuclear Leukocyte Migration [PE]
type: Class
subclass of: Decreased Cellular Migration [PE]
Display_Name: Decreased Polymorphonuclear Leukocyte Migration
NUI: N0000010246
RxNorm_CUI: 990417
UMLS_CUI: C1371595
code: C31850
imported from: NDF-RT.owl

Decreased Fibroblast Migration [PE]
type: Class
subclass of: Decreased Cellular Migration [PE]
Display_Name: Decreased Fibroblast Migration
NUI: N0000010248
RxNorm_CUI: 987533
UMLS_CUI: C1371593
code: C31854
imported from: NDF-RT.owl

Vascular Permeability Alteration [PE]
type: Class
subclass of: Vascular Alterations [PE]
Display_Name: Vascular Permeability Alteration
NUI: N0000010250
RxNorm_CUI: 1025930
UMLS_CUI: C1371588
code: C31858
imported from: NDF-RT.owl

Decreased Vascular Permeability [PE]
type: Class
subclass of: Vascular Permeability Alteration [PE]
Display_Name: Decreased Vascular Permeability
NUI: N0000010252
RxNorm_CUI: 984932
UMLS_CUI: C2825069
code: C31862
imported from: NDF-RT.owl

Decreased Capillary Permeability [PE]
type: Class
subclass of: Decreased Vascular Permeability [PE]
Display_Name: Decreased Capillary Permeability
NUI: N0000010253
RxNorm_CUI: 985585
UMLS_CUI: C0232378
code: C31864
imported from: NDF-RT.owl

Smooth Muscle Tone Alteration [PE]
type: Class
subclass of: Musculoskeletal Activity Alteration [PE]
subclass of: Autonomic Nervous System Activity Alteration [PE]
Display_Name: Smooth Muscle Tone Alteration
NUI: N0000010268
RxNorm_CUI: 985732
UMLS_CUI: C1371604
code: C31894
imported from: NDF-RT.owl

imatinib [Chemical/Ingredient]
type: Class
subclass of: Pyrimidines [Chemical/Ingredient]
subclass of: Piperazines [Chemical/Ingredient]
Display_Name: imatinib
MeSH_CUI: M0424454
MeSH_DUI: C097613
MeSH_Name: imatinib
NUI: N0000010347
RxNorm_CUI: 282388
RxNorm_Name: imatinib
UMLS_CUI: C0935989
code: C53878
imported from: NDF-RT.owl

Drug Products by Generic Ingredient Combinations
type: Class
subclass of: Pharmaceutical Preparations
type: NamedIndividual
Display_Name: Drug Products by Generic Ingredient Combinations
NUI: N0000010582
RxNorm_CUI: 987399
UMLS_CUI: C2267084
code: C288626
imported from: NDF-RT.owl

A [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: A [Preparations]
NUI: N0000010583
RxNorm_CUI: 989498
UMLS_CUI: C2267085
code: C288627
imported from: NDF-RT.owl

B [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: B [Preparations]
NUI: N0000010584
RxNorm_CUI: 987472
UMLS_CUI: C2267086
code: C288628
imported from: NDF-RT.owl

C [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: C [Preparations]
NUI: N0000010585
RxNorm_CUI: 987820
UMLS_CUI: C2267087
code: C288629
imported from: NDF-RT.owl

D [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: D [Preparations]
NUI: N0000010586
RxNorm_CUI: 990856
UMLS_CUI: C2267088
code: C288630
imported from: NDF-RT.owl

E [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: E [Preparations]
NUI: N0000010587
RxNorm_CUI: 984666
UMLS_CUI: C2267089
code: C288631
imported from: NDF-RT.owl

F [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: F [Preparations]
NUI: N0000010588
RxNorm_CUI: 986610
UMLS_CUI: C2267090
code: C288632
imported from: NDF-RT.owl

G [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: G [Preparations]
NUI: N0000010589
RxNorm_CUI: 986405
UMLS_CUI: C2267091
code: C288633
imported from: NDF-RT.owl

H [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: H [Preparations]
NUI: N0000010590
RxNorm_CUI: 985945
UMLS_CUI: C2741642
code: C288634
imported from: NDF-RT.owl

I [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: I [Preparations]
NUI: N0000010591
RxNorm_CUI: 987875
UMLS_CUI: C2267092
code: C288635
imported from: NDF-RT.owl

L [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: L [Preparations]
NUI: N0000010594
RxNorm_CUI: 984195
UMLS_CUI: C2267094
code: C288638
imported from: NDF-RT.owl

M [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: M [Preparations]
NUI: N0000010595
RxNorm_CUI: 989499
UMLS_CUI: C2267095
code: C288639
imported from: NDF-RT.owl

N [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: N [Preparations]
NUI: N0000010596
RxNorm_CUI: 984993
UMLS_CUI: C2267096
code: C288640
imported from: NDF-RT.owl

P [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: P [Preparations]
NUI: N0000010598
RxNorm_CUI: 987400
UMLS_CUI: C2267098
code: C288642
imported from: NDF-RT.owl

R [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: R [Preparations]
NUI: N0000010600
RxNorm_CUI: 987269
UMLS_CUI: C2267100
code: C288644
imported from: NDF-RT.owl

T [Preparations]
type: Class
subclass of: Drug Products by Generic Ingredient Combinations
type: NamedIndividual
Display_Name: T [Preparations]
NUI: N0000010602
RxNorm_CUI: 989806
UMLS_CUI: C2267102
code: C288646
imported from: NDF-RT.owl

Papillomavirus Infections [Disease/Finding]
type: Class
subclass of: DNA Virus Infections [Disease/Finding]
subclass of: Tumor Virus Infections [Disease/Finding]
Display_Name: Papillomavirus Infections
MeSH_CUI: M0387084
MeSH_DUI: D030361
MeSH_Definition: Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
MeSH_Name: Papillomavirus Infections
NUI: N0000011003
RxNorm_CUI: 1027658
UMLS_CUI: C0950124
code: C291356
imported from: NDF-RT.owl

Carcinoma, Ductal [Disease/Finding]
type: Class
subclass of: Adenocarcinoma [Disease/Finding]
subclass of: Neoplasms, Ductal, Lobular, and Medullary [Disease/Finding]
Display_Name: Carcinoma, Ductal
MeSH_CUI: M0445446
MeSH_DUI: D044584
MeSH_Definition: Malignant neoplasms involving the ductal systems of any of a number of organs, such as the MAMMARY GLANDS, the PANCREAS, the PROSTATE, or the LACRIMAL GLAND.
MeSH_Name: Carcinoma, Ductal
NUI: N0000011087
RxNorm_CUI: 1025416
SNOMED_CID: 82711006
Synonym: Ductal Carcinoma
UMLS_CUI: C1176475
code: C291440
imported from: NDF-RT.owl

Genetic Diseases, Inborn [Disease/Finding]
type: Class
subclass of: Congenital, Hereditary, and Neonatal Diseases and Abnormalities [Disease/Finding]
Display_Name: Genetic Diseases, Inborn
MeSH_CUI: M0385531
MeSH_DUI: D030342
MeSH_Definition: Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero.
MeSH_Name: Genetic Diseases, Inborn
NUI: N0000011105
RxNorm_CUI: 1025368
Synonym: Inborn Genetic Diseases
UMLS_CUI: C0950123
code: C291458
imported from: NDF-RT.owl

Cardiomyopathies [Disease/Finding]
type: Class
subclass of: Heart Diseases [Disease/Finding]
type: NamedIndividual
Display_Name: Cardiomyopathies
MeSH_CUI: M0014337
MeSH_DUI: D009202
MeSH_Definition: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
MeSH_Name: Cardiomyopathies
NUI: N0000011137
RxNorm_CUI: 1025008
SNOMED_CID: 57809008
SNOMED_CID: 85898001
Synonym: Myocardial Diseases
Synonym: Myocardiopathies
UMLS_CUI: C0878544
code: C291490
imported from: NDF-RT.owl

Hormones [Chemical/Ingredient]
type: Class
subclass of: Hormones, Hormone Substitutes, and Hormone Antagonists [Chemical/Ingredient]
Display_Name: Hormones
MeSH_CUI: M0010538
MeSH_DUI: D006728
MeSH_Definition: Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
MeSH_Name: Hormones
NUI: N0000011172
RxNorm_CUI: 5436
Synonym: Hormone
UMLS_CUI: C0019932
code: C291528
imported from: NDF-RT.owl

Hormones, Hormone Substitutes, and Hormone Antagonists [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
Display_Name: Hormones, Hormone Substitutes, and Hormone Antagonists
MeSH_CUI: M0010540
MeSH_DUI: D006730
MeSH_Definition: A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists.
MeSH_Name: Hormones, Hormone Substitutes, and Hormone Antagonists
NUI: N0000011173
RxNorm_CUI: 5438
Synonym: Hormones, Substitutes, Antagonists
UMLS_CUI: C0019934
code: C291529
imported from: NDF-RT.owl

Secologanin Tryptamine Alkaloids [Chemical/Ingredient]
type: Class
subclass of: Indole Alkaloids [Chemical/Ingredient]
Display_Name: Secologanin Tryptamine Alkaloids
MeSH_CUI: M0456000
MeSH_DUI: D046948
MeSH_Definition: Compounds formed by condensation of secologanin with tryptamine resulting in a tetrahydro-beta-carboline which is processed further to a number of bioactive compounds. These are especially found in plants of the APOCYNACEAE; LOGANIACEAE; and RUBIACEAE families.
MeSH_Name: Secologanin Tryptamine Alkaloids
NUI: N0000011187
RxNorm_CUI: 469968
Synonym: Monoterpenoid Indole Alkaloids
Synonym: Secologanin Indole Alkaloids
Synonym: Terpenoid Indole Alkaloids
UMLS_CUI: C1449663
code: C291543
imported from: NDF-RT.owl

Indole Alkaloids [Chemical/Ingredient]
type: Class
subclass of: Alkaloids [Chemical/Ingredient]
subclass of: Indoles [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Indole Alkaloids
MeSH_CUI: M0377033
MeSH_DUI: D026121
MeSH_Definition: Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)
MeSH_Name: Indole Alkaloids
NUI: N0000011188
RxNorm_CUI: 287953
UMLS_CUI: C0949738
code: C291544
imported from: NDF-RT.owl

Biological Factors [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
Display_Name: Biological Factors
MeSH_CUI: M0002530
MeSH_DUI: D001685
MeSH_Definition: Endogenously-synthesized compounds that may influence biological phenomena or represent quantifiable biomarkers. Biological factors are a variety of extracellular substances that are not otherwise classified under ENZYMES; HORMONES or HORMONE ANTAGONISTS
MeSH_Name: Biological Factors
NUI: N0000011290
RxNorm_CUI: 1570
Synonym: Biologic Factors
Synonym: Biological Factor
Synonym: Factor, Biologic
Synonym: Factor, Biological
Synonym: Factors, Biological
UMLS_CUI: C0005515
code: C291646
imported from: NDF-RT.owl

Cytokines [Chemical/Ingredient]
type: Class
subclass of: Intercellular Signaling Peptides and Proteins [Chemical/Ingredient]
Display_Name: Cytokines
MeSH_CUI: M0024747
MeSH_DUI: D016207
MeSH_Definition: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
MeSH_Name: Cytokines
NUI: N0000011291
RxNorm_CUI: 40065
UMLS_CUI: C0079189
code: C291647
imported from: NDF-RT.owl

Corpus Luteum Hormones [Chemical/Ingredient]
type: Class
subclass of: Gonadal Hormones [Chemical/Ingredient]
Display_Name: Corpus Luteum Hormones
MeSH_CUI: M0005208
MeSH_DUI: D003339
MeSH_Name: Corpus Luteum Hormones
NUI: N0000011299
RxNorm_CUI: 2871
UMLS_CUI: C0010094
code: C291655
imported from: NDF-RT.owl

Gonadal Hormones [Chemical/Ingredient]
type: Class
subclass of: Hormones [Chemical/Ingredient]
Display_Name: Gonadal Hormones
MeSH_CUI: M0441053
MeSH_DUI: D042341
MeSH_Definition: Hormones produced by the GONADS, including both steroid and peptide hormones. The major steroid hormones include ESTRADIOL and PROGESTERONE from the OVARY, and TESTOSTERONE from the TESTIS. The major peptide hormones include ACTIVINS and INHIBINS.
MeSH_Name: Gonadal Hormones
NUI: N0000011300
RxNorm_CUI: 90006
UMLS_CUI: C0301819
code: C291656
imported from: NDF-RT.owl

Progesterone Congeners [Chemical/Ingredient]
type: Class
subclass of: Gonadal Steroid Hormones [Chemical/Ingredient]
Display_Name: Progesterone Congeners
MeSH_CUI: M0447349
MeSH_DUI: D045167
MeSH_Definition: Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.
MeSH_Name: Progesterone Congeners
NUI: N0000011301
RxNorm_CUI: 382321
UMLS_CUI: C1257993
code: C291657
imported from: NDF-RT.owl

Gonadal Steroid Hormones [Chemical/Ingredient]
type: Class
subclass of: Gonadal Hormones [Chemical/Ingredient]
Display_Name: Gonadal Steroid Hormones
MeSH_CUI: M0019744
MeSH_DUI: D012739
MeSH_Definition: Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE.
MeSH_Name: Gonadal Steroid Hormones
NUI: N0000011302
RxNorm_CUI: 9730
Synonym: Sex Hormones
Synonym: Sex Steroid Hormones
UMLS_CUI: C0036884
code: C291658
imported from: NDF-RT.owl

Aza Compounds [Chemical/Ingredient]
type: Class
subclass of: Organic Chemicals [Chemical/Ingredient]
Display_Name: Aza Compounds
MeSH_CUI: M0002056
MeSH_DUI: D001372
MeSH_Name: Aza Compounds
NUI: N0000011324
RxNorm_CUI: 1249
UMLS_CUI: C0004471
code: C291680
imported from: NDF-RT.owl

Macrocyclic Compounds [Chemical/Ingredient]
type: Class
subclass of: Polycyclic Compounds [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Macrocyclic Compounds
MeSH_CUI: M0456185
MeSH_DUI: D047028
MeSH_Definition: Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
MeSH_Name: Macrocyclic Compounds
NUI: N0000011330
RxNorm_CUI: 469970
Synonym: Macrocycle Compounds
UMLS_CUI: C1449665
code: C291686
imported from: NDF-RT.owl

Polycyclic Compounds [Chemical/Ingredient]
type: Class
subclass of: Chemical Ingredients [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Polycyclic Compounds
MeSH_CUI: M0017162
MeSH_DUI: D011083
MeSH_Definition: Compounds consisting of two or more fused ring structures.
MeSH_Name: Polycyclic Compounds
NUI: N0000011331
RxNorm_CUI: 8502
UMLS_CUI: C0032456
code: C291687
imported from: NDF-RT.owl

Intercellular Signaling Peptides and Proteins [Chemical/Ingredient]
type: Class
subclass of: Proteins [Chemical/Ingredient]
subclass of: Peptides [Chemical/Ingredient]
subclass of: Biological Factors [Chemical/Ingredient]
Display_Name: Intercellular Signaling Peptides and Proteins
MeSH_CUI: M0409590
MeSH_DUI: D036341
MeSH_Definition: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
MeSH_Name: Intercellular Signaling Peptides and Proteins
NUI: N0000011384
RxNorm_CUI: 337799
UMLS_CUI: C1136108
code: C291740
imported from: NDF-RT.owl

Receptor Tyrosine Kinase Inhibitors [MoA]
type: Class
subclass of: Tyrosine Kinase Inhibitors [MoA]
Display_Name: Receptor Tyrosine Kinase Inhibitors
NUI: N0000020000
RxNorm_CUI: 987029
UMLS_CUI: C2267115
code: C300385
imported from: NDF-RT.owl

Tyrosine Kinase Inhibitors [MoA]
type: Class
subclass of: Protein Kinase Inhibitors [MoA]
Display_Name: Tyrosine Kinase Inhibitors
NUI: N0000020001
RxNorm_CUI: 1028392
UMLS_CUI: C2757011
code: C300386
imported from: NDF-RT.owl

Vascular Alterations [PE]
type: Class
subclass of: Cardiovascular Activity Alteration [PE]
Display_Name: Vascular Alterations
NUI: N0000020002
RxNorm_CUI: 984378
UMLS_CUI: C2267116
code: C300387
imported from: NDF-RT.owl

Bcr-Abl Tyrosine Kinase Inhibitors [MoA]
type: Class
subclass of: Receptor Tyrosine Kinase Inhibitors [MoA]
Display_Name: Bcr-Abl Tyrosine Kinase Inhibitors
NUI: N0000020009
RxNorm_CUI: 984994
Synonym: Bcr-Abl Tyrosine Kinase Inhibitor
UMLS_CUI: C2267122
code: C300394
imported from: NDF-RT.owl

Cellular Growth Phase Reduction [PE]
type: Class
subclass of: Cellular Growth Phase Alteration [PE]
Display_Name: Cellular Growth Phase Reduction
NUI: N0000020013
RxNorm_CUI: 986120
UMLS_CUI: C2267126
code: C300398
imported from: NDF-RT.owl

14-alpha Demethylase Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: 14-alpha Demethylase Inhibitors
NUI: N0000020025
RxNorm_CUI: 989952
UMLS_CUI: C2267137
code: C300411
imported from: NDF-RT.owl

INTERFERON ALFA-2A
type: Class
subclass of: I [Preparations]
subclass of: Class
  intersection of: Restriction
    on property: CI_with
    some values from: Acquired Immunodeficiency Syndrome [Disease/Finding]
  intersection of: Restriction
    on property: CI_with
    some values from: Sarcoma, Kaposi [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Autoimmune Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Interferon Alfa-2a [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Biological Response Modifiers [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Cellular Growth Phase Arrest [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Cytokine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Brain Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Carcinoma, Renal Cell [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Cryoglobulinemia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hepatitis D [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hemangioma [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Carcinoma, Hepatocellular [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Ileal Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Leukemia, Hairy Cell [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Macular Degeneration [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Melanoma [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Multiple Myeloma [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Mycosis Fungoides [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Sarcoma, Kaposi [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Sezary Syndrome [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Skin Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Skin Ulcer [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Thrombocythemia, Essential [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Thrombocytopenia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Warts [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Colorectal Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hypereosinophilic Syndrome [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hepatitis C, Chronic [Disease/Finding]
type: NamedIndividual
Display_Name: INTERFERON ALFA-2A
Level: Ingredient
NUI: N0000020127
RxNorm_CUI: 5879
RxNorm_Name: Interferon Alfa-2a
Status: Active
UMLS_CUI: C0021734
VANDF_Record: <VANDF_Record>50.6^183^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>183</VA_IEN>
VUID: 4022121
code: C15918
imported from: NDF-RT.owl

RIMANTADINE
type: Class
subclass of: R [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Rimantadine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Ion Channel Interactions [MoA]
type: NamedIndividual
Display_Name: RIMANTADINE
Level: Ingredient
NUI: N0000021902
RxNorm_CUI: 9386
RxNorm_Name: Rimantadine
Status: Active
UMLS_CUI: C0035629
VANDF_Record: <VANDF_Record>50.6^3161^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3161</VA_IEN>
VUID: 4023897
code: C19566
imported from: NDF-RT.owl

INTERFERON BETA-1B
type: Class
subclass of: I [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: interferon beta-1b [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Biological Response Modifiers [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Cellular Growth Phase Arrest [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Immunologically Active Molecule Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Multiple Sclerosis [Disease/Finding]
type: NamedIndividual
Display_Name: INTERFERON BETA-1B
Level: Ingredient
NUI: N0000021905
RxNorm_CUI: 72257
RxNorm_Name: interferon beta-1b
Status: Active
UMLS_CUI: C0244713
VANDF_Record: <VANDF_Record>50.6^3172^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3172</VA_IEN>
VUID: 4023900
code: C15946
imported from: NDF-RT.owl

GEMCITABINE
type: Class
subclass of: G [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: gemcitabine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Integrity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Carcinoma, Pancreatic Ductal [Disease/Finding]
type: NamedIndividual
Display_Name: GEMCITABINE
Level: Ingredient
NUI: N0000022036
RxNorm_CUI: 12574
RxNorm_Name: gemcitabine
Status: Active
UMLS_CUI: C0045093
VANDF_Record: <VANDF_Record>50.6^3358^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3358</VA_IEN>
VUID: 4024031
code: C15022
imported from: NDF-RT.owl

NELFINAVIR
type: Class
subclass of: N [Preparations]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Simvastatin [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Triazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Cisapride [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Midazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Astemizole [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Ergotamines [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Quinidine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Phenylketonurias [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Nelfinavir [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: HIV Protease Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Acquired Immunodeficiency Syndrome [Disease/Finding]
type: NamedIndividual
Display_Name: NELFINAVIR
Level: Ingredient
NUI: N0000022055
RxNorm_CUI: 134527
RxNorm_Name: Nelfinavir
Status: Active
UMLS_CUI: C0525005
VANDF_Record: <VANDF_Record>50.6^3394^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3394</VA_IEN>
VUID: 4024050
code: C17618
imported from: NDF-RT.owl

TOREMIFENE
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Toremifene [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Selective Estrogen Receptor Modulators [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Replication [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Ovarian Estrogen Secretion [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Neoplasms, Hormone-Dependent [Disease/Finding]
type: NamedIndividual
Display_Name: TOREMIFENE
Level: Ingredient
NUI: N0000022107
RxNorm_CUI: 38409
RxNorm_Name: Toremifene
Status: Active
UMLS_CUI: C0076836
VANDF_Record: <VANDF_Record>50.6^3476^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3476</VA_IEN>
VUID: 4024102
code: C21018
imported from: NDF-RT.owl

GEMCITABINE HYDROCHLORIDE
type: Class
subclass of: GEMCITABINE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: gemcitabine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Integrity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Carcinoma, Pancreatic Ductal [Disease/Finding]
type: NamedIndividual
Display_Name: GEMCITABINE HYDROCHLORIDE
FDA_UNII: U347PV74IL
Level: Ingredient
NUI: N0000022977
RxNorm_CUI: 236234
RxNorm_Name: Gemcitabine hydrochloride
Status: Active
UMLS_CUI: C0771488
VANDF_Record: <VANDF_Record>50.416^3642^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3642</VA_IEN>
VUID: 4020975
code: C15024
imported from: NDF-RT.owl

DIGITOXIN
type: Class
subclass of: DIGITALIS
subclass of: Restriction
  on property: CI_with
  some values from: Amyloidosis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Cardiomyopathy, Hypertrophic [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Heart Block [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pericarditis, Constrictive [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Ventricular Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Tachycardia, Ventricular [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Digitoxin [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Na-K ATPases Interactions [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Conduction System Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Negative Chronotropy [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Nodal Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Positive Inotropy [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Flutter [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Cardiac Output, Low [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Shock, Cardiogenic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tachycardia, Supraventricular [Disease/Finding]
type: NamedIndividual
Display_Name: DIGITOXIN
FDA_UNII: E90NZP2L9U
Level: Ingredient
NUI: N0000145817
RxNorm_CUI: 3403
RxNorm_Name: Digitoxin
Status: Active
UMLS_CUI: C0012258
VANDF_Record: <VANDF_Record>50.416^20^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>20</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^9^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>9</VA_IEN>
VUID: 4017429
code: C13764
imported from: NDF-RT.owl

RESERPINE
type: Class
subclass of: R [Preparations]
subclass of: Restriction
  on property: CI_PE
  some values from: Electrical Activity Alteration [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Colitis, Ulcerative [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Depressive Disorder [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Hypotension [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Peptic Ulcer [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Reserpine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Norepinephrine Uptake Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Sympathetic Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Blood Pressure [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Hypertension [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Dyskinesias [Disease/Finding]
type: NamedIndividual
Display_Name: RESERPINE
FDA_UNII: 8B1QWR724A
Level: Ingredient
NUI: N0000145891
RxNorm_CUI: 9260
RxNorm_Name: Reserpine
Status: Active
UMLS_CUI: C0035179
VANDF_Record: <VANDF_Record>50.416^98^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>98</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^57^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>57</VA_IEN>
VUID: 4017506
code: C19522
imported from: NDF-RT.owl

HYDROXYPROGESTERONE CAPROATE
type: Class
subclass of: HYDROXYPROGESTERONE
subclass of: Restriction
  on property: CI_with
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Cerebral Hemorrhage [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Thromboembolism [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Thrombophlebitis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: 17-alpha-hydroxy-progesterone caproate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Progestational Hormone Receptor Agonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Uterine Smooth Muscle Contraction or Tone [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Inhibit Ovarian Follicular Phase [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Inhibit Ovulation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Breast Glandular Development [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Uterine Secretory Phase [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Abortion, Spontaneous [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Amenorrhea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Endometriosis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Uterine Hemorrhage [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Uterine Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: HYDROXYPROGESTERONE CAPROATE
FDA_UNII: 276F2O42F5
Level: Ingredient
NUI: N0000145993
RxNorm_CUI: 12488
RxNorm_Name: hydroxyprogesterone caproate (USP)
Status: Active
UMLS_CUI: C0044971
VANDF_Record: <VANDF_Record>50.416^207^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>207</VA_IEN>
VUID: 4017613
code: C15582
imported from: NDF-RT.owl

FLUPHENAZINE HYDROCHLORIDE
type: Class
subclass of: FLUPHENAZINE
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Blood Coagulation Disorders [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Brain Damage, Chronic [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Fluphenazine Hydrochloride [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
type: NamedIndividual
Display_Name: FLUPHENAZINE HYDROCHLORIDE
FDA_UNII: ZOU145W1XL
Level: Ingredient
NUI: N0000146092
RxNorm_CUI: 203207
RxNorm_Name: Fluphenazine Hydrochloride
Status: Active
UMLS_CUI: C0700567
VANDF_Record: <VANDF_Record>50.416^318^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>318</VA_IEN>
VUID: 4017723
code: C14814
imported from: NDF-RT.owl

TRIFLUPROMAZINE HYDROCHLORIDE
type: Class
subclass of: TRIFLUPROMAZINE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Reye Syndrome [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Triflupromazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Adrenergic alpha-Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Serotonin Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Serotonin Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Hiccup [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: TRIFLUPROMAZINE HYDROCHLORIDE
FDA_UNII: 9E75N4A5HM
Level: Ingredient
NUI: N0000146110
RxNorm_CUI: 91125
RxNorm_Name: Triflupromazine hydrochloride
Status: Active
UMLS_CUI: C0304376
VANDF_Record: <VANDF_Record>50.416^339^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>339</VA_IEN>
VUID: 4017744
code: C21136
imported from: NDF-RT.owl

BENZTROPINE MESYLATE
type: Class
subclass of: BENZTROPINE
subclass of: Restriction
  on property: CI_with
  some values from: Urinary Bladder Neck Obstruction [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Esophageal Achalasia [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Intestinal Obstruction [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Myasthenia Gravis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Peptic Ulcer [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Young Child [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Benzatropine Methanesulfonate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Cholinergic Muscarinic Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Receptor Interactions [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Histamine Receptor Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Parasympathetic Acetylcholine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Respiratory Secretions [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Dopamine Activity Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Positive Chronotropy [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Pupillary Dilation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Salivation Inhibition [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Abnormalities, Drug-Induced [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Parkinson Disease [Disease/Finding]
type: NamedIndividual
Display_Name: BENZTROPINE MESYLATE
FDA_UNII: WMJ8TL7510
Level: Ingredient
NUI: N0000146182
RxNorm_CUI: 18927
RxNorm_Name: benztropine mesylate
Status: Active
UMLS_CUI: C0053156
VANDF_Record: <VANDF_Record>50.416^419^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>419</VA_IEN>
VUID: 4017824
code: C11662
imported from: NDF-RT.owl

PROMETHAZINE HYDROCHLORIDE
type: Class
subclass of: PROMETHAZINE
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Disorganized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Promethazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Histamine H1 Receptor Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Histamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Motion Sickness [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Postoperative Complications [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Rhinitis, Allergic, Perennial [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: PROMETHAZINE HYDROCHLORIDE
FDA_UNII: R61ZEH7I1I
Level: Ingredient
NUI: N0000146203
RxNorm_CUI: 142445
RxNorm_Name: Promethazine Hydrochloride
Status: Active
UMLS_CUI: C0546876
VANDF_Record: <VANDF_Record>50.416^441^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>441</VA_IEN>
VUID: 4017846
code: C19210
imported from: NDF-RT.owl

CHLORPROMAZINE HYDROCHLORIDE
type: Class
subclass of: CHLORPROMAZINE
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Chlorpromazine Hydrochloride [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Adrenergic alpha-Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Anxiety Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hiccup [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tetanus [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Porphyria, Acute Intermittent [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Attention Deficit and Disruptive Behavior Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: CHLORPROMAZINE HYDROCHLORIDE
FDA_UNII: 9WP59609J6
Level: Ingredient
NUI: N0000146213
RxNorm_CUI: 104728
RxNorm_Name: Chlorpromazine hydrochloride
Status: Active
UMLS_CUI: C0355077
VANDF_Record: <VANDF_Record>50.416^455^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>455</VA_IEN>
VUID: 4017860
code: C12754
imported from: NDF-RT.owl

CHLORPROMAZINE
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Chlorpromazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Adrenergic alpha-Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Anxiety Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hiccup [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tetanus [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Porphyria, Acute Intermittent [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Attention Deficit and Disruptive Behavior Disorders [Disease/Finding]
type: NamedIndividual
Display_Name: CHLORPROMAZINE
FDA_UNII: U42B7VYA4P
Level: Ingredient
NUI: N0000146214
RxNorm_CUI: 2403
RxNorm_Name: Chlorpromazine
Status: Active
UMLS_CUI: C0008286
VANDF_Record: <VANDF_Record>50.416^456^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>456</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^216^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>216</VA_IEN>
VUID: 4017861
code: C12752
imported from: NDF-RT.owl

DIGOXIN
type: Class
subclass of: DIGITALIS
subclass of: Class
  intersection of: Restriction
    on property: CI_with
    some values from: Atrial Fibrillation [Disease/Finding]
  intersection of: Restriction
    on property: CI_with
    some values from: Wolff-Parkinson-White Syndrome [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Amyloidosis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Cardiomyopathy, Hypertrophic [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Heart Block [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pericarditis, Constrictive [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Ventricular Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Tachycardia, Ventricular [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Digoxin [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Na-K ATPases Interactions [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Conduction System Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Negative Chronotropy [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Nodal Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Positive Inotropy [PE]
subclass of: Restriction
  on property: has_PK
  some values from: Renal Excretion [PK]
subclass of: Restriction
  on property: may_prevent
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Flutter [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Cardiac Output, Low [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Shock, Cardiogenic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tachycardia, Supraventricular [Disease/Finding]
subclass of: Restriction
  on property: site_of_metabolism
  some values from: Intestinal Metabolism [PK]
type: NamedIndividual
Display_Name: DIGOXIN
FDA_UNII: 73K4184T59
Level: Ingredient
NUI: N0000146388
RxNorm_CUI: 3407
RxNorm_Name: Digoxin
Status: Active
UMLS_CUI: C0012265
VANDF_Record: <VANDF_Record>50.416^644^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>644</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^372^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>372</VA_IEN>
VUID: 4018047
code: C13772
imported from: NDF-RT.owl

METHYLPREDNISOLONE
type: Class
subclass of: M [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Skin Diseases, Infectious [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Infant [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Methylprednisolone [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Lipoxygenase Inhibitors [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Glucocorticoid Receptor Agonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Carbohydrate Metabolism Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Glucocorticoid Secretion [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Leukotriene Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Prostaglandin Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Protein Synthesis [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Thromboxane Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Lipid Metabolism Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Lysosomal Function Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Polymorphonuclear Leukocyte Migration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Fibroblast Migration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Capillary Permeability [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Autoimmune Diseases [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hematologic Diseases [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Inflammation [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Neurologic Manifestations [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Respiratory Distress Syndrome, Adult [Disease/Finding]
type: NamedIndividual
Display_Name: METHYLPREDNISOLONE
FDA_UNII: X4W7ZR7023
Level: Ingredient
NUI: N0000146409
RxNorm_CUI: 6902
RxNorm_Name: Methylprednisolone
Status: Active
UMLS_CUI: C0025815
VANDF_Record: <VANDF_Record>50.416^665^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>665</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^394^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>394</VA_IEN>
VUID: 4018068
code: C17198
imported from: NDF-RT.owl

CHLOROQUINE PHOSPHATE
type: Class
subclass of: CHLOROQUINE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Psoriasis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Retinal Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Vision Disorders [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: chloroquine diphosphate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Metabolic Rate [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Prostaglandin Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Nucleic Acid Replication Alteration [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Malaria [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Amebiasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Lupus Erythematosus, Discoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Avian [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pemphigus [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Scleroderma, Systemic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Falciparum [Disease/Finding]
type: NamedIndividual
Display_Name: CHLOROQUINE PHOSPHATE
FDA_UNII: 6E17K3343P
Level: Ingredient
NUI: N0000146559
RxNorm_CUI: 20863
RxNorm_Name: chloroquine phosphate
Status: Active
UMLS_CUI: C0055447
VANDF_Record: <VANDF_Record>50.416^826^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>826</VA_IEN>
VUID: 4018228
code: C12714
imported from: NDF-RT.owl

HEXACHLOROPHENE
type: Class
subclass of: H [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Hexachlorophene [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Cell Membrane Integrity [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Staphylococcal Skin Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Acne Vulgaris [Disease/Finding]
type: NamedIndividual
Display_Name: HEXACHLOROPHENE
FDA_UNII: IWW5FV6NK2
Level: Ingredient
NUI: N0000146582
RxNorm_CUI: 5293
RxNorm_Name: Hexachlorophene
Status: Active
UMLS_CUI: C0019435
VANDF_Record: <VANDF_Record>50.416^850^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>850</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^557^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>557</VA_IEN>
VUID: 4018252
code: C15398
imported from: NDF-RT.owl

HYDROXYCHLOROQUINE SULFATE
type: Class
subclass of: HYDROXYCHLOROQUINE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Vision Disorders [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Hydroxychloroquine Sulfate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Physiochemical Activity [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Endocytosis [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Lupus Erythematosus, Systemic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Photosensitivity Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Porphyria Cutanea Tarda [Disease/Finding]
type: NamedIndividual
Display_Name: HYDROXYCHLOROQUINE SULFATE
FDA_UNII: 8Q2869CNVH
Level: Ingredient
NUI: N0000146583
RxNorm_CUI: 153972
RxNorm_Name: Hydroxychloroquine Sulfate
Status: Active
UMLS_CUI: C0596007
VANDF_Record: <VANDF_Record>50.416^851^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>851</VA_IEN>
VUID: 4018253
code: C15570
imported from: NDF-RT.owl

NICLOSAMIDE
type: Class
subclass of: N [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Niclosamide [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Metabolic Rate [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Helminthiasis [Disease/Finding]
type: NamedIndividual
Display_Name: NICLOSAMIDE
FDA_UNII: 8KK8CQ2K8G
Level: Ingredient
NUI: N0000146594
RxNorm_CUI: 7402
RxNorm_Name: Niclosamide
Status: Active
UMLS_CUI: C0028017
VANDF_Record: <VANDF_Record>50.416^862^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>862</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^573^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>573</VA_IEN>
VUID: 4018264
code: C17666
imported from: NDF-RT.owl

TAMOXIFEN CITRATE
type: Class
subclass of: TAMOXIFEN
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Warfarin [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Tamoxifen Citrate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Selective Estrogen Receptor Modulators [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Replication [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Ovarian Estrogen Secretion [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Ovulation [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Gynecomastia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pancreatic Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Puberty, Precocious [Disease/Finding]
type: NamedIndividual
Display_Name: TAMOXIFEN CITRATE
FDA_UNII: 7FRV7310N6
Level: Ingredient
NUI: N0000146786
RxNorm_CUI: 40137
RxNorm_Name: Tamoxifen Citrate
Status: Active
UMLS_CUI: C0079589
VANDF_Record: <VANDF_Record>50.416^1060^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1060</VA_IEN>
VUID: 4018462
code: C20578
imported from: NDF-RT.owl

CYCLOSPORINE
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: CI_MoA
  some values from: Immunologic Adjuvants [MoA]
subclass of: Restriction
  on property: CI_with
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Hypertension [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Neoplastic Processes [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Psoriasis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Kidney Failure [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Lactation [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Cyclosporine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Cytokine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Cytokine Production [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased T Lymphocyte Production [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Glomerulosclerosis, Focal Segmental [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Lupus Erythematosus, Systemic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Myasthenia Gravis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psoriasis [Disease/Finding]
type: NamedIndividual
Display_Name: CYCLOSPORINE
FDA_UNII: 83HN0GTJ6D
Level: Ingredient
NUI: N0000147064
RxNorm_CUI: 3008
RxNorm_Name: Cyclosporine
Status: Active
UMLS_CUI: C0010592
VANDF_Record: <VANDF_Record>50.416^1363^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1363</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1100^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1100</VA_IEN>
VUID: 4018761
code: C13348
imported from: NDF-RT.owl

DIGITALIS
type: Class
subclass of: D [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Amyloidosis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Cardiomyopathy, Hypertrophic [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Heart Block [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pericarditis, Constrictive [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Ventricular Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Tachycardia, Ventricular [Disease/Finding]
subclass of: Restriction
  on property: has_MoA
  some values from: Na-K ATPases Interactions [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Conduction System Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Negative Chronotropy [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Nodal Depolarization [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Positive Inotropy [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Fibrillation [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Atrial Flutter [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Cardiac Output, Low [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Heart Failure [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Shock, Cardiogenic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tachycardia, Supraventricular [Disease/Finding]
type: NamedIndividual
Display_Name: DIGITALIS
FDA_UNII: F1T8QT9U8B
Level: Ingredient
NUI: N0000147198
RxNorm_CUI: 91235
RxNorm_Name: Digitalis preparation
Status: Active
UMLS_CUI: C0304520
VANDF_Record: <VANDF_Record>50.416^1508^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1508</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1303^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1303</VA_IEN>
VUID: 4018904
code: C13756
imported from: NDF-RT.owl

THIETHYLPERAZINE MALEATE
type: Class
subclass of: THIETHYLPERAZINE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Thiethylperazine Malate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Central Nervous System Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Central Nervous System Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Emesis Suppression [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vertigo [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: THIETHYLPERAZINE MALEATE
FDA_UNII: RUK64CF26E
Level: Ingredient
NUI: N0000147331
RxNorm_CUI: 71529
RxNorm_Name: Thiethylperazine Malate
Status: Active
UMLS_CUI: C0242518
VANDF_Record: <VANDF_Record>50.416^1670^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1670</VA_IEN>
VUID: 4019064
code: C20802
imported from: NDF-RT.owl

CETYLPYRIDINIUM CHLORIDE
type: Class
subclass of: CETYLPYRIDINIUM
subclass of: Restriction
  on property: has_Ingredient
  some values from: Cetylpyridinium Chloride [Chemical/Ingredient]
type: NamedIndividual
Display_Name: CETYLPYRIDINIUM CHLORIDE
FDA_UNII: D9OM4SK49P
Level: Ingredient
NUI: N0000147354
RxNorm_CUI: 2287
RxNorm_Name: Cetylpyridinium Chloride
Status: Active
UMLS_CUI: C0007907
VANDF_Record: <VANDF_Record>50.416^1702^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1702</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^2211^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>2211</VA_IEN>
VUID: 4019096
code: C12610
imported from: NDF-RT.owl

RIBAVIRIN
type: Class
subclass of: R [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Anemia [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Heart Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Hemoglobinopathies [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Kidney Failure [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Hepatitis, Autoimmune [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Ribavirin [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Replication [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased RNA Replication [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Adenovirus Infections, Human [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: West Nile Fever [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Respiratory Syncytial Virus Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Hepatitis C, Chronic [Disease/Finding]
type: NamedIndividual
Display_Name: RIBAVIRIN
FDA_UNII: 49717AWG6K
Level: Ingredient
NUI: N0000147496
RxNorm_CUI: 9344
RxNorm_Name: Ribavirin
Status: Active
UMLS_CUI: C0035525
VANDF_Record: <VANDF_Record>50.416^1910^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1910</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1909^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1909</VA_IEN>
VUID: 4019299
code: C19534
imported from: NDF-RT.owl

ASTEMIZOLE
type: Class
subclass of: A [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Astemizole [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Histamine H1 Receptor Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Histamine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Conjunctivitis, Allergic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Rhinitis, Allergic, Perennial [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Urticaria [Disease/Finding]
type: NamedIndividual
Display_Name: ASTEMIZOLE
Level: Ingredient
NUI: N0000147536
RxNorm_CUI: 42328
RxNorm_Name: Astemizole
Status: Active
UMLS_CUI: C0085170
VANDF_Record: <VANDF_Record>50.416^1992^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>1992</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1989^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1989</VA_IEN>
VUID: 4019379
code: C11390
imported from: NDF-RT.owl

CLOMIPRAMINE HYDROCHLORIDE
type: Class
subclass of: CLOMIPRAMINE
subclass of: Restriction
  on property: CI_MoA
  some values from: Monoamine Oxidase Inhibitors [MoA]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Myocardial Infarction [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Clomipramine Hydrochloride [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Norepinephrine Uptake Inhibitors [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Serotonin Uptake Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Serotonin Degradation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Central Nervous System Norepinephrine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Depressive Disorder [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Obsessive-Compulsive Disorder [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Panic Disorder [Disease/Finding]
subclass of: Restriction
  on property: site_of_metabolism
  some values from: Hepatic Metabolism [PK]
type: NamedIndividual
Display_Name: CLOMIPRAMINE HYDROCHLORIDE
FDA_UNII: 2LXW0L6GWJ
Level: Ingredient
NUI: N0000147612
RxNorm_CUI: 81984
RxNorm_Name: Clomipramine Hydrochloride
Status: Active
UMLS_CUI: C0282107
VANDF_Record: <VANDF_Record>50.416^2106^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2106</VA_IEN>
VUID: 4019492
code: C12984
imported from: NDF-RT.owl

TERCONAZOLE
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: terconazole [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: 14-alpha Demethylase Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Cell Membrane Integrity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Candidiasis, Vulvovaginal [Disease/Finding]
type: NamedIndividual
Display_Name: TERCONAZOLE
FDA_UNII: 0KJ2VE664U
Level: Ingredient
NUI: N0000147638
RxNorm_CUI: 37806
RxNorm_Name: terconazole
Status: Active
UMLS_CUI: C0076115
VANDF_Record: <VANDF_Record>50.416^2136^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2136</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^2169^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>2169</VA_IEN>
VUID: 4019521
code: C20680
imported from: NDF-RT.owl

AMODIAQUINE
type: Class
subclass of: A [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Amodiaquine [Chemical/Ingredient]
type: NamedIndividual
Display_Name: AMODIAQUINE
FDA_UNII: 220236ED28
Level: Ingredient
NUI: N0000147704
RxNorm_CUI: 720
RxNorm_Name: Amodiaquine
Status: Active
UMLS_CUI: C0002641
VANDF_Record: <VANDF_Record>50.416^2229^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2229</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1852^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1852</VA_IEN>
VUID: 4019610
code: C11084
imported from: NDF-RT.owl

BENZTROPINE
type: Class
subclass of: B [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Urinary Bladder Neck Obstruction [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Esophageal Achalasia [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Intestinal Obstruction [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Myasthenia Gravis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Peptic Ulcer [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Young Child [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Benztropine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Cholinergic Muscarinic Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Receptor Interactions [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Histamine Receptor Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Parasympathetic Acetylcholine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Respiratory Secretions [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Dopamine Activity Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Positive Chronotropy [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Pupillary Dilation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Salivation Inhibition [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Abnormalities, Drug-Induced [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Parkinson Disease [Disease/Finding]
type: NamedIndividual
Display_Name: BENZTROPINE
FDA_UNII: 1NHL2J4X8K
Level: Ingredient
NUI: N0000147723
RxNorm_CUI: 1424
RxNorm_Name: Benztropine
Status: Active
UMLS_CUI: C0005098
VANDF_Record: <VANDF_Record>50.416^2249^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2249</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^190^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>190</VA_IEN>
VUID: 4019630
code: C11660
imported from: NDF-RT.owl

CETYLPYRIDINIUM
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Cetylpyridinium [Chemical/Ingredient]
type: NamedIndividual
Display_Name: CETYLPYRIDINIUM
Level: Ingredient
NUI: N0000147763
RxNorm_CUI: 2286
RxNorm_Name: Cetylpyridinium
Status: Active
UMLS_CUI: C0007906
VANDF_Record: <VANDF_Record>50.416^2290^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2290</VA_IEN>
VUID: 4019671
code: C12608
imported from: NDF-RT.owl

CHLOROQUINE
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Psoriasis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Retinal Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Vision Disorders [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Chloroquine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Metabolic Rate [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Prostaglandin Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Nucleic Acid Replication Alteration [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Malaria [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Amebiasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Lupus Erythematosus, Discoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Avian [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pemphigus [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Scleroderma, Systemic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Falciparum [Disease/Finding]
type: NamedIndividual
Display_Name: CHLOROQUINE
FDA_UNII: 886U3H6UFF
Level: Ingredient
NUI: N0000147767
RxNorm_CUI: 2393
RxNorm_Name: Chloroquine
Status: Active
UMLS_CUI: C0008269
VANDF_Record: <VANDF_Record>50.416^2294^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2294</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^529^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>529</VA_IEN>
VUID: 4019675
code: C12708
imported from: NDF-RT.owl

CLOMIPRAMINE
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: CI_MoA
  some values from: Monoamine Oxidase Inhibitors [MoA]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Myocardial Infarction [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Clomipramine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Norepinephrine Uptake Inhibitors [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Serotonin Uptake Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Serotonin Degradation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Central Nervous System Norepinephrine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Depressive Disorder [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Obsessive-Compulsive Disorder [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Panic Disorder [Disease/Finding]
subclass of: Restriction
  on property: site_of_metabolism
  some values from: Hepatic Metabolism [PK]
type: NamedIndividual
Display_Name: CLOMIPRAMINE
FDA_UNII: NUV44L116D
Level: Ingredient
NUI: N0000147779
RxNorm_CUI: 2597
RxNorm_Name: Clomipramine
Status: Active
UMLS_CUI: C0009010
VANDF_Record: <VANDF_Record>50.416^2306^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2306</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^2137^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>2137</VA_IEN>
VUID: 4019687
code: C12982
imported from: NDF-RT.owl

EMETINE
type: Class
subclass of: E [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Emetine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: may_treat
  some values from: Amebiasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Fascioloidiasis [Disease/Finding]
type: NamedIndividual
Display_Name: EMETINE
FDA_UNII: X8D5EPO80M
Level: Ingredient
NUI: N0000147834
RxNorm_CUI: 3820
RxNorm_Name: Emetine
Status: Active
UMLS_CUI: C0013974
VANDF_Record: <VANDF_Record>50.416^2362^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2362</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^31^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>31</VA_IEN>
VUID: 4019743
code: C14188
imported from: NDF-RT.owl

FLUPHENAZINE
type: Class
subclass of: F [Preparations]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Blood Coagulation Disorders [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Brain Damage, Chronic [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Fluphenazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
type: NamedIndividual
Display_Name: FLUPHENAZINE
FDA_UNII: S79426A41Z
Level: Ingredient
NUI: N0000147853
RxNorm_CUI: 4496
RxNorm_Name: Fluphenazine
Status: Active
UMLS_CUI: C0016368
VANDF_Record: <VANDF_Record>50.416^2382^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2382</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^115^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>115</VA_IEN>
VUID: 4019762
code: C14804
imported from: NDF-RT.owl

HYDROXYCHLOROQUINE
type: Class
subclass of: H [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Vision Disorders [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Hydroxychloroquine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Physiochemical Activity [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Enzyme Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Endocytosis [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Arthritis, Rheumatoid [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Lupus Erythematosus, Systemic [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Photosensitivity Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Porphyria Cutanea Tarda [Disease/Finding]
type: NamedIndividual
Display_Name: HYDROXYCHLOROQUINE
FDA_UNII: 4QWG6N8QKH
Level: Ingredient
NUI: N0000147871
RxNorm_CUI: 5521
RxNorm_Name: Hydroxychloroquine
Status: Active
UMLS_CUI: C0020336
VANDF_Record: <VANDF_Record>50.416^2403^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2403</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^558^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>558</VA_IEN>
VUID: 4019780
code: C15568
imported from: NDF-RT.owl

HYDROXYPROGESTERONE
type: Class
subclass of: H [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Cerebral Hemorrhage [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Thromboembolism [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Thrombophlebitis [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Hydroxyprogesterones [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Progestational Hormone Receptor Agonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Uterine Smooth Muscle Contraction or Tone [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Inhibit Ovarian Follicular Phase [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Inhibit Ovulation [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Breast Glandular Development [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Uterine Secretory Phase [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Abortion, Spontaneous [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Amenorrhea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Endometriosis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Uterine Hemorrhage [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Uterine Neoplasms [Disease/Finding]
type: NamedIndividual
Display_Name: HYDROXYPROGESTERONE
Level: Ingredient
NUI: N0000147872
RxNorm_CUI: 5542
RxNorm_Name: Hydroxyprogesterone
Status: Active
UMLS_CUI: C0020387
VANDF_Record: <VANDF_Record>50.416^2404^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2404</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^100^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>100</VA_IEN>
VUID: 4019781
code: C15578
imported from: NDF-RT.owl

LOPERAMIDE
type: Class
subclass of: L [Preparations]
subclass of: Class
  union of: Class
    intersection of: Restriction
      on property: CI_with
      some values from: Diarrhea [Disease/Finding]
    intersection of: Restriction
      on property: CI_with
      some values from: Hemorrhage [Disease/Finding]
  union of: Class
    intersection of: Restriction
      on property: CI_with
      some values from: Diarrhea [Disease/Finding]
    intersection of: Restriction
      on property: CI_with
      some values from: Salmonella Infections [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Constipation [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Enterocolitis, Pseudomembranous [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Loperamide [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased GI Motility [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulation Large Intestine Fluid/Electrolyte Absorption [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulation Small Intestine Fluid/Electrolyte Absorption [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Colonic Diseases, Functional [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Diarrhea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Dysentery, Bacillary [Disease/Finding]
type: NamedIndividual
Display_Name: LOPERAMIDE
FDA_UNII: 6X9OC3H4II
Level: Ingredient
NUI: N0000147893
RxNorm_CUI: 6468
RxNorm_Name: Loperamide
Status: Active
UMLS_CUI: C0023992
VANDF_Record: <VANDF_Record>50.416^2427^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2427</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1766^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1766</VA_IEN>
VUID: 4019804
code: C16610
imported from: NDF-RT.owl

MEFLOQUINE
type: Class
subclass of: M [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Epilepsy [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Mefloquine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: may_prevent
  some values from: Malaria, Falciparum [Disease/Finding]
subclass of: Restriction
  on property: may_prevent
  some values from: Malaria, Vivax [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Falciparum [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Malaria, Vivax [Disease/Finding]
type: NamedIndividual
Display_Name: MEFLOQUINE
FDA_UNII: TML814419R
Level: Ingredient
NUI: N0000147900
RxNorm_CUI: 6694
RxNorm_Name: Mefloquine
Status: Active
UMLS_CUI: C0025153
VANDF_Record: <VANDF_Record>50.416^2434^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2434</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^2143^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>2143</VA_IEN>
VUID: 4019811
code: C16862
imported from: NDF-RT.owl

PHENAZOPYRIDINE
type: Class
subclass of: P [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Kidney Diseases [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Phenazopyridine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Unknown Cellular or Molecular Interaction [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Renal/Urological Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Urological Manifestations [Disease/Finding]
type: NamedIndividual
Display_Name: PHENAZOPYRIDINE
FDA_UNII: K2J09EMJ52
Level: Ingredient
NUI: N0000147969
RxNorm_CUI: 8120
RxNorm_Name: Phenazopyridine
Status: Active
UMLS_CUI: C0031379
VANDF_Record: <VANDF_Record>50.416^2509^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2509</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1218^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1218</VA_IEN>
VUID: 4019884
code: C18490
imported from: NDF-RT.owl

PROMETHAZINE
type: Class
subclass of: P [Preparations]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Disorganized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Promethazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Histamine H1 Receptor Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Histamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Motion Sickness [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Postoperative Complications [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Rhinitis, Allergic, Perennial [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: PROMETHAZINE
FDA_UNII: FF28EJQ494
Level: Ingredient
NUI: N0000147995
RxNorm_CUI: 8745
RxNorm_Name: Promethazine
Status: Active
UMLS_CUI: C0033405
VANDF_Record: <VANDF_Record>50.416^2535^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2535</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^214^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>214</VA_IEN>
VUID: 4019910
code: C19204
imported from: NDF-RT.owl

TAMOXIFEN
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Warfarin [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Tamoxifen [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Selective Estrogen Receptor Modulators [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Replication [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Ovarian Estrogen Secretion [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Stimulate Ovulation [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Gynecomastia [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pancreatic Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Puberty, Precocious [Disease/Finding]
type: NamedIndividual
Display_Name: TAMOXIFEN
FDA_UNII: 094ZI81Y45
Level: Ingredient
NUI: N0000148024
RxNorm_CUI: 10324
RxNorm_Name: Tamoxifen
Status: Active
UMLS_CUI: C0039286
VANDF_Record: <VANDF_Record>50.416^2565^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2565</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^772^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>772</VA_IEN>
VUID: 4019939
code: C20576
imported from: NDF-RT.owl

THIETHYLPERAZINE
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Thiethylperazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Central Nervous System Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Central Nervous System Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Emesis Suppression [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Hypothalamic Endocrine Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vertigo [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: THIETHYLPERAZINE
FDA_UNII: 8ETK1WAF6R
Level: Ingredient
NUI: N0000148028
RxNorm_CUI: 10471
RxNorm_Name: Thiethylperazine
Status: Active
UMLS_CUI: C0039865
VANDF_Record: <VANDF_Record>50.416^2569^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2569</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^1562^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>1562</VA_IEN>
VUID: 4019943
code: C20800
imported from: NDF-RT.owl

THIOTHIXENE
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_PE
  some values from: Decreased Central Nervous System Organized Electrical Activity [PE]
subclass of: Restriction
  on property: CI_with
  some values from: Blood Coagulation Disorders [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Coma [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Thiothixene [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Adrenergic alpha-Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Schizophrenia [Disease/Finding]
type: NamedIndividual
Display_Name: THIOTHIXENE
FDA_UNII: 7318FJ13YJ
Level: Ingredient
NUI: N0000148032
RxNorm_CUI: 10510
RxNorm_Name: Thiothixene
Status: Active
UMLS_CUI: C0039955
VANDF_Record: <VANDF_Record>50.416^2573^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2573</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^825^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>825</VA_IEN>
VUID: 4019947
code: C20832
imported from: NDF-RT.owl

TRIFLUPROMAZINE
type: Class
subclass of: T [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Reye Syndrome [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Triflupromazine [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Adrenergic alpha-Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Serotonin Antagonists [MoA]
subclass of: Restriction
  on property: has_MoA
  some values from: Dopamine Antagonists [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Dopamine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Norepinephrine Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Serotonin Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Hiccup [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Nausea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pain [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psychotic Disorders [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Vomiting [Disease/Finding]
type: NamedIndividual
Display_Name: TRIFLUPROMAZINE
FDA_UNII: RO16TQF95Y
Level: Ingredient
NUI: N0000148043
RxNorm_CUI: 10805
RxNorm_Name: Triflupromazine
Status: Active
UMLS_CUI: C0040989
VANDF_Record: <VANDF_Record>50.416^2584^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2584</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^133^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>133</VA_IEN>
VUID: 4019958
code: C21134
imported from: NDF-RT.owl

AZITHROMYCIN
type: Class
subclass of: A [Preparations]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Pimozide [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Liver Diseases [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Azithromycin [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Protein Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Protein Synthesis [PE]
subclass of: Restriction
  on property: has_PK
  some values from: Hepatic Excretion [PK]
subclass of: Restriction
  on property: may_prevent
  some values from: Endocarditis, Bacterial [Disease/Finding]
subclass of: Restriction
  on property: may_prevent
  some values from: Mycobacterium Infections, Atypical [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Chlamydia Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Haemophilus Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Mycobacterium Infections, Atypical [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Otitis Media [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Pneumonia, Mycoplasma [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Skin Diseases, Infectious [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Staphylococcal Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Streptococcal Infections [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Tonsillitis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Urethritis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Neisseriaceae Infections [Disease/Finding]
type: NamedIndividual
Display_Name: AZITHROMYCIN
FDA_UNII: F94OW58Y8V
Level: Ingredient
NUI: N0000148074
RxNorm_CUI: 18631
RxNorm_Name: Azithromycin
Status: Active
UMLS_CUI: C0052796
VANDF_Record: <VANDF_Record>50.416^2648^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>2648</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^2712^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>2712</VA_IEN>
VUID: 4020019
code: C11448
imported from: NDF-RT.owl

MYCOPHENOLATE MOFETIL
type: Class
subclass of: MYCOPHENOLATE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Lactation [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: mycophenolate mofetil [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Lymphocyte Cell Production [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psoriasis [Disease/Finding]
type: NamedIndividual
Display_Name: MYCOPHENOLATE MOFETIL
FDA_UNII: 9242ECW6R0
Level: Ingredient
NUI: N0000148406
RxNorm_CUI: 68149
RxNorm_Name: mycophenolate mofetil
Status: Active
UMLS_CUI: C0209368
VANDF_Record: <VANDF_Record>50.416^3581^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3581</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3295^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3295</VA_IEN>
VUID: 4020921
code: C17502
imported from: NDF-RT.owl

RITONAVIR
type: Class
subclass of: R [Preparations]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Amiodarone [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Simvastatin [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Dihydroergotamine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Triazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Pimozide [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Ergotamine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Bepridil [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Cisapride [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Propafenone [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Midazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Flecainide [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Astemizole [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Terfenadine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Methylergonovine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Quinidine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Ritonavir [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: HIV Protease Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Acquired Immunodeficiency Syndrome [Disease/Finding]
type: NamedIndividual
Display_Name: RITONAVIR
FDA_UNII: O3J8G9O825
Level: Ingredient
NUI: N0000148436
RxNorm_CUI: 85762
RxNorm_Name: Ritonavir
Status: Active
UMLS_CUI: C0292818
VANDF_Record: <VANDF_Record>50.416^3629^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3629</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3349^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3349</VA_IEN>
VUID: 4020963
code: C19590
imported from: NDF-RT.owl

PENCICLOVIR
type: Class
subclass of: P [Preparations]
subclass of: Class
  intersection of: Restriction
    on property: CI_ChemClass
    some values from: famciclovir [Chemical/Ingredient]
  intersection of: Restriction
    on property: CI_with
    some values from: Drug Toxicity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: penciclovir [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Nucleic Acid Replication Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Herpes Labialis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Epstein-Barr Virus Infections [Disease/Finding]
type: NamedIndividual
Display_Name: PENCICLOVIR
FDA_UNII: 359HUE8FJC
Level: Ingredient
NUI: N0000148462
RxNorm_CUI: 59839
RxNorm_Name: penciclovir
Status: Active
UMLS_CUI: C0164815
VANDF_Record: <VANDF_Record>50.416^3659^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3659</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3378^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3378</VA_IEN>
VUID: 4020992
code: C18312
imported from: NDF-RT.owl

NELFINAVIR MESYLATE
type: Class
subclass of: NELFINAVIR
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Simvastatin [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Triazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Cisapride [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Midazolam [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Astemizole [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Ergotamines [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_ChemClass
  some values from: Quinidine [Chemical/Ingredient]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Phenylketonurias [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Nelfinavir Mesylate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: HIV Protease Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Acquired Immunodeficiency Syndrome [Disease/Finding]
type: NamedIndividual
Display_Name: NELFINAVIR MESYLATE
FDA_UNII: 98D603VP8V
Level: Ingredient
NUI: N0000148479
RxNorm_CUI: 266565
RxNorm_Name: Nelfinavir Mesylate
Status: Active
UMLS_CUI: C0886530
VANDF_Record: <VANDF_Record>50.416^3677^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3677</VA_IEN>
VUID: 4021010
code: C17620
imported from: NDF-RT.owl

IVERMECTIN
type: Class
subclass of: I [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Ivermectin [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Chloride Channel Interactions [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Nervous System Activity Alteration [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Ascariasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Elephantiasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Mansonelliasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Onchocerciasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Scabies [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Strongyloidiasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Trichuriasis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Enterobiasis [Disease/Finding]
type: NamedIndividual
Display_Name: IVERMECTIN
FDA_UNII: 8883YP2R6D
Level: Ingredient
NUI: N0000148510
RxNorm_CUI: 6069
RxNorm_Name: Ivermectin
Status: Active
UMLS_CUI: C0022322
VANDF_Record: <VANDF_Record>50.416^3714^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3714</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3436^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3436</VA_IEN>
VUID: 4021046
code: C16206
imported from: NDF-RT.owl

TOREMIFENE CITRATE
type: Class
subclass of: TOREMIFENE
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: Toremifene Citrate [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Selective Estrogen Receptor Modulators [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased DNA Replication [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Ovarian Estrogen Secretion [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Breast Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Neoplasms, Hormone-Dependent [Disease/Finding]
type: NamedIndividual
Display_Name: TOREMIFENE CITRATE
FDA_UNII: 2498Y783QT
Level: Ingredient
NUI: N0000148546
RxNorm_CUI: 49953
RxNorm_Name: Toremifene Citrate
Status: Active
UMLS_CUI: C0117339
VANDF_Record: <VANDF_Record>50.416^3756^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3756</VA_IEN>
VUID: 4021088
code: C21020
imported from: NDF-RT.owl

LOPINAVIR
type: Class
subclass of: L [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: lopinavir [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: HIV Protease Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Increased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Acquired Immunodeficiency Syndrome [Disease/Finding]
subclass of: Restriction
  on property: has role
  some values from: CIDO_0000257
type: NamedIndividual
Display_Name: LOPINAVIR
FDA_UNII: 2494G1JF75
Level: Ingredient
NUI: N0000148672
RxNorm_CUI: 195088
RxNorm_Name: lopinavir
Status: Active
UMLS_CUI: C0674432
VANDF_Record: <VANDF_Record>50.416^3900^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3900</VA_IEN>
VUID: 4021228
code: C16616
imported from: NDF-RT.owl

IMATINIB
type: Class
subclass of: I [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: imatinib [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Bcr-Abl Tyrosine Kinase Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Increased T Lymphocyte Destruction [PE]
type: NamedIndividual
Display_Name: IMATINIB
FDA_UNII: BKJ8M8G5HI
Level: Ingredient
NUI: N0000148698
RxNorm_CUI: 282388
RxNorm_Name: imatinib
Status: Active
UMLS_CUI: C0935989
VANDF_Record: <VANDF_Record>50.416^3929^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3929</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3696^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3696</VA_IEN>
VUID: 4021257
code: C53876
imported from: NDF-RT.owl

IMATINIB MESYLATE
type: Class
subclass of: IMATINIB
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Pregnancy [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: imatinib [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Bcr-Abl Tyrosine Kinase Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Connective Tissue Alteration [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Increased T Lymphocyte Destruction [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Blast Crisis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Gastrointestinal Neoplasms [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Leukemia, Myeloid, Accelerated Phase [Disease/Finding]
type: NamedIndividual
Display_Name: IMATINIB MESYLATE
FDA_UNII: 8A1O1M485B
Level: Ingredient
NUI: N0000148699
RxNorm_CUI: 284924
RxNorm_Name: Imatinib mesylate
Status: Active
UMLS_CUI: C0939537
VANDF_Record: <VANDF_Record>50.416^3930^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>3930</VA_IEN>
VUID: 4021258
code: C53880
imported from: NDF-RT.owl

NITAZOXANIDE
type: Class
subclass of: N [Preparations]
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: nitazoxanide [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Uncouplers [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Metabolic Rate [PE]
subclass of: Restriction
  on property: may_treat
  some values from: Cryptosporidiosis [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Diarrhea [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Giardiasis [Disease/Finding]
type: NamedIndividual
Display_Name: NITAZOXANIDE
FDA_UNII: SOA12P041N
Level: Ingredient
NUI: N0000148784
RxNorm_CUI: 31819
RxNorm_Name: nitazoxanide
Status: Active
UMLS_CUI: C0068788
VANDF_Record: <VANDF_Record>50.416^4039^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4039</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3842^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3842</VA_IEN>
VUID: 4021365
code: C31484
imported from: NDF-RT.owl

MYCOPHENOLIC ACID
type: Class
subclass of: MYCOPHENOLATE MOFETIL
subclass of: Restriction
  on property: CI_with
  some values from: Drug Hypersensitivity [Disease/Finding]
subclass of: Restriction
  on property: CI_with
  some values from: Lactation [Disease/Finding]
subclass of: Restriction
  on property: has_Ingredient
  some values from: mycophenolate mofetil [Chemical/Ingredient]
subclass of: Restriction
  on property: has_MoA
  some values from: Nucleic Acid Synthesis Inhibitors [MoA]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Immunologically Active Molecule Activity [PE]
subclass of: Restriction
  on property: has_PE
  some values from: Decreased Lymphocyte Cell Production [PE]
subclass of: Restriction
  on property: may_prevent
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Graft vs Host Disease [Disease/Finding]
subclass of: Restriction
  on property: may_treat
  some values from: Psoriasis [Disease/Finding]
type: NamedIndividual
Display_Name: MYCOPHENOLIC ACID
FDA_UNII: HU9DX48N0T
Level: Ingredient
NUI: N0000148832
RxNorm_CUI: 7145
RxNorm_Name: Mycophenolic Acid
Status: Active
UMLS_CUI: C0026933
VANDF_Record: <VANDF_Record>50.416^4095^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4095</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^3937^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>3937</VA_IEN>
VUID: 4021418
code: C273300
imported from: NDF-RT.owl

Triparanol [Chemical/Ingredient]
type: Class
subclass of: Benzene Derivatives [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Triparanol
MeSH_CUI: M0022011
MeSH_DUI: D014308
MeSH_Definition: Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
MeSH_Name: Triparanol
NUI: N0000166394
RxNorm_CUI: 10846
Synonym: Benzeneethanol, 4-chloro-alpha-(4-(2-(diethylamino)ethoxy)phenyl)-alpha-(4-methylphenyl)-
UMLS_CUI: C0041088
code: C7757245273072
imported from: NDF-RT.owl

Cinanserin [Chemical/Ingredient]
type: Class
subclass of: Cinnamates [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cinanserin
MeSH_CUI: M0004484
MeSH_DUI: D002928
MeSH_Definition: A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.
MeSH_Name: Cinanserin
NUI: N0000166641
RxNorm_CUI: 2543
Synonym: 2-Propenamide, N-(2-((3-(dimethylamino)propyl)thio)phenyl)-3-phenyl-
UMLS_CUI: C0008788
code: C7757801986565
imported from: NDF-RT.owl

Oxyclozanide [Chemical/Ingredient]
type: Class
subclass of: Salicylanilides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Oxyclozanide
MeSH_CUI: M0015663
MeSH_DUI: D010097
MeSH_Definition: Anthelmintic used in grazing animals for fasciola and cestode infestations.
MeSH_Name: Oxyclozanide
NUI: N0000166893
RxNorm_CUI: 7802
Synonym: Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-
Synonym: Oxiclozanidum
UMLS_CUI: C0030046
code: C7758280989622
imported from: NDF-RT.owl

Nocodazole [Chemical/Ingredient]
type: Class
subclass of: Benzimidazoles [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Nocodazole
MeSH_CUI: M0024123
MeSH_DUI: D015739
MeSH_Definition: Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
MeSH_Name: Nocodazole
NUI: N0000166936
RxNorm_CUI: 7497
Synonym: Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester
Synonym: Oncodazole
UMLS_CUI: C0028247
code: C7758479301978
imported from: NDF-RT.owl

Monensin [Chemical/Ingredient]
type: Class
subclass of: Furans [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Monensin
MeSH_CUI: M0014007
MeSH_DUI: D008985
MeSH_Definition: An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
MeSH_Name: Monensin
NUI: N0000167131
RxNorm_CUI: 7026
UMLS_CUI: C0026408
code: C7758754814648
imported from: NDF-RT.owl

Anisomycin [Chemical/Ingredient]
type: Class
subclass of: Pyrrolidines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Anisomycin
MeSH_CUI: M0001251
MeSH_DUI: D000841
MeSH_Definition: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
MeSH_Name: Anisomycin
NUI: N0000167149
RxNorm_CUI: 857
Synonym: 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2alpha,3alpha,4beta))-
UMLS_CUI: C0003082
code: C7758765830014
imported from: NDF-RT.owl

Cycloheximide [Chemical/Ingredient]
type: Class
subclass of: Piperidones [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Cycloheximide
MeSH_CUI: M0005473
MeSH_DUI: D003513
MeSH_Definition: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
MeSH_Name: Cycloheximide
NUI: N0000167211
RxNorm_CUI: 2993
Synonym: 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-
Synonym: Cicloheximide
UMLS_CUI: C0010572
code: C7758827087800
imported from: NDF-RT.owl

Harmine [Chemical/Ingredient]
type: Class
subclass of: Carbolines [Chemical/Ingredient]
subclass of: Indole Alkaloids [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Harmine
MeSH_CUI: M0009805
MeSH_DUI: D006247
MeSH_Definition: Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic Parkinson disease in the 1920's.
MeSH_Name: Harmine
NUI: N0000167259
RxNorm_CUI: 5101
Synonym: 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-
Synonym: Banisterine
Synonym: Leucoharmine
Synonym: Telepathine
Synonym: Yageine
UMLS_CUI: C0018605
code: C7758364911462
imported from: NDF-RT.owl

Fluspirilene [Chemical/Ingredient]
type: Class
subclass of: Spiro Compounds [Chemical/Ingredient]
subclass of: Imidazoles [Chemical/Ingredient]
subclass of: Piperidines [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Fluspirilene
MeSH_CUI: M0008650
MeSH_DUI: D005484
MeSH_Definition: A long-acting injectable antipsychotic agent used for chronic schizophrenia.
MeSH_Name: Fluspirilene
NUI: N0000167366
RxNorm_CUI: 4507
RxNorm_Name: Fluspirilene
Synonym: 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(4-fluorophenyl)butyl)-1-phenyl-
Synonym: Spirodiflamine
UMLS_CUI: C0016383
code: C7758700772025
imported from: NDF-RT.owl

Bufanolides [Chemical/Ingredient]
type: Class
subclass of: Cardiac Glycosides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Bufanolides
MeSH_CUI: M0003002
MeSH_DUI: D002018
MeSH_Definition: Cyclopentanophenanthrenes with a 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. They are found in BUFONIDAE and often possess cardiotonic properties.
MeSH_Name: Bufanolides
NUI: N0000167413
RxNorm_CUI: 1795
UMLS_CUI: C0006350
code: C7759104670845
imported from: NDF-RT.owl

Oligomycins [Chemical/Ingredient]
type: Class
subclass of: Macrolides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Oligomycins
MeSH_CUI: M0015277
MeSH_DUI: D009840
MeSH_Definition: A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
MeSH_Name: Oligomycins
NUI: N0000168432
RxNorm_CUI: 7636
Synonym: Oligomycin
UMLS_CUI: C0028951
code: C7758210287620
imported from: NDF-RT.owl

Proscillaridin [Chemical/Ingredient]
type: Class
subclass of: Bufanolides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Proscillaridin
MeSH_CUI: M0017785
MeSH_DUI: D011442
MeSH_Definition: A cardiotonic glycoside isolated from Scilla maritima var. alba (Squill).
MeSH_Name: Proscillaridin
NUI: N0000168447
RxNorm_CUI: 8795
RxNorm_Name: Proscillaridin
Synonym: Bufa-4,20,22-trienolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-14-hydroxy-, (3beta)-
Synonym: Desglucotransvaaline
Synonym: Proscillaridin A
Synonym: Proscillaridine
Synonym: Scillarenin Rhamnoside
UMLS_CUI: C0033513
code: C7759106809664
imported from: NDF-RT.owl

Teicoplanin [Chemical/Ingredient]
type: Class
subclass of: Glycopeptides [Chemical/Ingredient]
Display_Name: Teicoplanin
MeSH_CUI: M0026325
MeSH_DUI: D017334
MeSH_Definition: Glycopeptide antibiotic complex from Actinoplanes teichomyceticus active against gram-positive bacteria. It consists of five major components each with a different fatty acid moiety.
MeSH_Name: Teicoplanin
NUI: N0000170298
RxNorm_CUI: 57021
RxNorm_Name: Teicoplanin
Synonym: Teichomycin
UMLS_CUI: C0145106
code: C7761627916676
imported from: NDF-RT.owl

Depsipeptides [Chemical/Ingredient]
type: Class
subclass of: Peptides, Cyclic [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Depsipeptides
MeSH_CUI: M0458175
MeSH_DUI: D047630
MeSH_Definition: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.
MeSH_Name: Depsipeptides
NUI: N0000170351
RxNorm_CUI: 253508
UMLS_CUI: C0796678
code: C7759071624466
imported from: NDF-RT.owl

Valinomycin [Chemical/Ingredient]
type: Class
subclass of: Depsipeptides [Chemical/Ingredient]
type: NamedIndividual
Display_Name: Valinomycin
MeSH_CUI: M0022498
MeSH_DUI: D014634
MeSH_Definition: A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
MeSH_Name: Valinomycin
NUI: N0000170352
RxNorm_CUI: 11116
UMLS_CUI: C0042287
code: C7759071830917
imported from: NDF-RT.owl

Renal Insufficiency [Disease/Finding]
type: Class
subclass of: Kidney Diseases [Disease/Finding]
Display_Name: Renal Insufficiency
MeSH_CUI: M0480487
MeSH_DUI: D051437
MeSH_Definition: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
MeSH_Name: Renal Insufficiency
NUI: N0000171642
RxNorm_CUI: 1026620
Synonym: Kidney Insufficiency
UMLS_CUI: C1565489
code: C7769506319378
imported from: NDF-RT.owl

ANIDULAFUNGIN
type: Class
subclass of: A [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: anidulafungin [Chemical/Ingredient]
type: NamedIndividual
Display_Name: ANIDULAFUNGIN
FDA_UNII: 9HLM53094I
Level: Ingredient
NUI: N0000171752
RxNorm_CUI: 341018
RxNorm_Name: anidulafungin
Status: Active
UMLS_CUI: C1142738
VANDF_Record: <VANDF_Record>50.416^4274^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4274</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4117^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4117</VA_IEN>
VUID: 4025092
code: C23260279896467
imported from: NDF-RT.owl

DALBAVANCIN
type: Class
subclass of: D [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: dalbavancin [Chemical/Ingredient]
type: NamedIndividual
Display_Name: DALBAVANCIN
Level: Ingredient
NUI: N0000171775
RxNorm_CUI: 354674
Status: Active
UMLS_CUI: C1172636
VANDF_Record: <VANDF_Record>50.416^4301^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4301</VA_IEN>
VUID: 4025243
code: C23283814211303
imported from: NDF-RT.owl

Protein Kinase Inhibitors [MoA]
type: Class
subclass of: Kinase Inhibitors [MoA]
Display_Name: Protein Kinase Inhibitors
NUI: N0000175076
RxNorm_CUI: 993161
UMLS_CUI: C2757016
code: C634438
imported from: NDF-RT.owl

Kinase Inhibitors [MoA]
type: Class
subclass of: Enzyme Inhibitors [MoA]
Display_Name: Kinase Inhibitors
NUI: N0000175082
RxNorm_CUI: 1025684
UMLS_CUI: C1152564
code: C634444
imported from: NDF-RT.owl

anidulafungin [Chemical/Ingredient]
type: Class
subclass of: Echinocandins [Chemical/Ingredient]
Display_Name: anidulafungin
MeSH_CUI: M0436249
MeSH_DUI: C102786
MeSH_Name: anidulafungin
NUI: N0000175344
RxNorm_CUI: 341018
RxNorm_Name: anidulafungin
UMLS_CUI: C1142738
code: C25703935168855
imported from: NDF-RT.owl

Cholinergic Interactions [MoA]
type: Class
subclass of: Receptor Interactions [MoA]
Display_Name: Cholinergic Interactions
NUI: N0000175368
RxNorm_CUI: 987379
UMLS_CUI: C2266879
code: C634751
imported from: NDF-RT.owl

Cholinergic Antagonists [MoA]
type: Class
subclass of: Cholinergic Interactions [MoA]
Display_Name: Cholinergic Antagonists
NUI: N0000175370
RxNorm_CUI: 1030384
UMLS_CUI: C2757022
code: C634753
imported from: NDF-RT.owl

Corticosteroid Hormone Receptor Agonists [MoA]
type: Class
subclass of: Steroid Hormone Receptor Agonists [MoA]
Display_Name: Corticosteroid Hormone Receptor Agonists
NUI: N0000175450
RxNorm_CUI: 988660
UMLS_CUI: C2266939
code: C634830
imported from: NDF-RT.owl

Decreased Immunologic Activity [PE]
type: Class
subclass of: Immunologic Activity Alteration [PE]
Display_Name: Decreased Immunologic Activity
NUI: N0000175550
RxNorm_CUI: 989722
Synonym: Immune Suppression
Synonym: Immune System Suppression
Synonym: Immunologic Suppression
Synonym: Immunosuppression
UMLS_CUI: C1373218
code: C634943
imported from: NDF-RT.owl

Increased Immunologic Activity [PE]
type: Class
subclass of: Immunologic Activity Alteration [PE]
Display_Name: Increased Immunologic Activity
NUI: N0000175551
RxNorm_CUI: 990348
Synonym: Immune Stimulation
Synonym: Immune System Stimulation
Synonym: Immunologic Stimulation
Synonym: Immunostimulation
UMLS_CUI: C2267003
code: C634944
imported from: NDF-RT.owl

Autonomic Nervous System Activity Alteration [PE]
type: Class
subclass of: Peripheral Nervous System Activity Alteration [PE]
Display_Name: Autonomic Nervous System Activity Alteration
NUI: N0000175642
RxNorm_CUI: 990764
UMLS_CUI: C2267060
code: C635035
imported from: NDF-RT.owl

Parasympathetic Activity Alteration [PE]
type: Class
subclass of: Autonomic Nervous System Activity Alteration [PE]
Display_Name: Parasympathetic Activity Alteration
NUI: N0000175646
RxNorm_CUI: 986849
UMLS_CUI: C2267064
code: C635039
imported from: NDF-RT.owl

Sympathetic Activity Alteration [PE]
type: Class
subclass of: Autonomic Nervous System Activity Alteration [PE]
Display_Name: Sympathetic Activity Alteration
NUI: N0000175647
RxNorm_CUI: 987557
UMLS_CUI: C2267065
code: C635040
imported from: NDF-RT.owl

Decreased Parasympathetic Activity [PE]
type: Class
subclass of: Parasympathetic Activity Alteration [PE]
Display_Name: Decreased Parasympathetic Activity
NUI: N0000175648
RxNorm_CUI: 984223
Synonym: Parasympatholytic Activity
UMLS_CUI: C2267066
code: C635041
imported from: NDF-RT.owl

Decreased Sympathetic Activity [PE]
type: Class
subclass of: Sympathetic Activity Alteration [PE]
Display_Name: Decreased Sympathetic Activity
NUI: N0000175650
RxNorm_CUI: 986974
Synonym: Sympatholytic Activity
UMLS_CUI: C2267068
code: C635043
imported from: NDF-RT.owl

Central Nervous System Activity Alteration [PE]
type: Class
subclass of: Nervous System Activity Alteration [PE]
Display_Name: Central Nervous System Activity Alteration
NUI: N0000175724
RxNorm_CUI: 991694
UMLS_CUI: C2917136
code: C635130
imported from: NDF-RT.owl

Peripheral Nervous System Activity Alteration [PE]
type: Class
subclass of: Nervous System Activity Alteration [PE]
Display_Name: Peripheral Nervous System Activity Alteration
NUI: N0000175725
RxNorm_CUI: 992027
UMLS_CUI: C2917266
code: C635131
imported from: NDF-RT.owl

Central Nervous System Depression [PE]
type: Class
subclass of: Central Nervous System Activity Alteration [PE]
Display_Name: Central Nervous System Depression
NUI: N0000175728
RxNorm_CUI: 991695
UMLS_CUI: C2917137
code: C635134
imported from: NDF-RT.owl

DASATINIB
type: Class
subclass of: D [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: dasatinib [Chemical/Ingredient]
type: NamedIndividual
Display_Name: DASATINIB
FDA_UNII: RBZ1571X5H
Level: Ingredient
NUI: N0000176043
RxNorm_CUI: 475342
RxNorm_Name: dasatinib
Status: Active
UMLS_CUI: C1455147
VANDF_Record: <VANDF_Record>50.416^4401^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4401</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4184^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4184</VA_IEN>
VUID: 4025488
code: C50.416.4401
imported from: NDF-RT.owl

MYCOPHENOLATE
type: Class
subclass of: M [Preparations]
type: NamedIndividual
Display_Name: MYCOPHENOLATE
Level: Ingredient
NUI: N0000176078
RxNorm_CUI: 265323
RxNorm_Name: MYCOPHENOLATE
Status: Active
UMLS_CUI: C0883242
VANDF_Record: <VANDF_Record>50.416^4438^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4438</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4198^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4198</VA_IEN>
VUID: 4025608
code: C50.416.4438
imported from: NDF-RT.owl

NILOTINIB
type: Class
subclass of: N [Preparations]
type: NamedIndividual
Display_Name: NILOTINIB
FDA_UNII: F41401512X
Level: Ingredient
NUI: N0000176124
RxNorm_CUI: 662281
RxNorm_Name: nilotinib
Status: Active
UMLS_CUI: C1721377
VANDF_Record: <VANDF_Record>50.416^4485^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4485</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4315^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4315</VA_IEN>
VUID: 4026964
code: C50.416.4485
imported from: NDF-RT.owl

CICLESONIDE
type: Class
subclass of: C [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: ciclesonide [Chemical/Ingredient]
type: NamedIndividual
Display_Name: CICLESONIDE
FDA_UNII: S59502J185
Level: Ingredient
NUI: N0000176150
RxNorm_CUI: 274964
RxNorm_Name: ciclesonide
Status: Active
UMLS_CUI: C0907850
VANDF_Record: <VANDF_Record>50.416^4511^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4511</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4361^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4361</VA_IEN>
VUID: 4027427
code: C50.416.4511
imported from: NDF-RT.owl

ELTROMBOPAG
type: Class
subclass of: E [Preparations]
subclass of: Restriction
  on property: has_Ingredient
  some values from: eltrombopag [Chemical/Ingredient]
type: NamedIndividual
Display_Name: ELTROMBOPAG
Level: Ingredient
NUI: N0000177933
RxNorm_CUI: 711942
RxNorm_Name: eltrombopag
Status: Active
UMLS_CUI: C1831905
VANDF_Record: <VANDF_Record>50.416^4547^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4547</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4405^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4405</VA_IEN>
VUID: 4028105
code: C50.416.4547
imported from: NDF-RT.owl

EVEROLIMUS
type: Class
subclass of: E [Preparations]
type: NamedIndividual
Display_Name: EVEROLIMUS
Level: Ingredient
NUI: N0000178379
RxNorm_CUI: 141704
RxNorm_Name: everolimus
Status: Active
UMLS_CUI: C0541315
VANDF_Record: <VANDF_Record>50.416^4578^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4578</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4453^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4453</VA_IEN>
VUID: 4028636
code: C50.416.4578
imported from: NDF-RT.owl

Blood Pressure Alteration [PE]
type: Class
subclass of: Cardiovascular Activity Alteration [PE]
Display_Name: Blood Pressure Alteration
NUI: N0000178476
RxNorm_CUI: 991626
UMLS_CUI: C2917124
code: C637932
imported from: NDF-RT.owl

Decreased Blood Pressure [PE]
type: Class
subclass of: Blood Pressure Alteration [PE]
type: NamedIndividual
Display_Name: Decreased Blood Pressure
NUI: N0000178477
RxNorm_CUI: 991700
UMLS_CUI: C2917141
code: C637933
imported from: NDF-RT.owl

Echinocandins [Chemical/Ingredient]
type: Class
subclass of: Peptides, Cyclic [Chemical/Ingredient]
Display_Name: Echinocandins
MeSH_CUI: M0507131
MeSH_DUI: D054714
MeSH_Definition: Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
MeSH_Name: Echinocandins
NUI: N0000178715
RxNorm_CUI: 386841
UMLS_CUI: C1268551
code: CMSHM0507131
imported from: NDF-RT.owl

Azabicyclo Compounds [Chemical/Ingredient]
type: Class
subclass of: Bicyclo Compounds, Heterocyclic [Chemical/Ingredient]
subclass of: Aza Compounds [Chemical/Ingredient]
Display_Name: Azabicyclo Compounds
MeSH_CUI: M0499252
MeSH_DUI: D053961
MeSH_Definition: Bicyclic bridged compounds that contain a nitrogen which has three bonds. The nomenclature indicates the number of atoms in each path around the rings, such as [2.2.2] for three equal length paths. Some members are TROPANES and BETA LACTAMS.
MeSH_Name: Azabicyclo Compounds
NUI: N0000178749
RxNorm_CUI: 737880
UMLS_CUI: C1955840
code: CMSHM0499252
imported from: NDF-RT.owl

Cetylpyridinium Chloride [Chemical/Ingredient]
type: Class
subclass of: Cetylpyridinium [Chemical/Ingredient]
Display_Name: Cetylpyridinium Chloride
MeSH_CUI: M0003974
MeSH_DUI: D002594
MeSH_Name: Cetylpyridinium Chloride
NUI: N0000178899
RxNorm_CUI: 2287
RxNorm_Name: Cetylpyridinium Chloride
UMLS_CUI: C0007907
code: CMSHM0003974
imported from: NDF-RT.owl

17-alpha-hydroxy-progesterone caproate [Chemical/Ingredient]
type: Class
subclass of: Hydroxyprogesterones [Chemical/Ingredient]
Display_Name: 17-alpha-hydroxy-progesterone caproate
MeSH_CUI: M0074009
MeSH_DUI: C020365
MeSH_Name: 17-alpha-hydroxy-progesterone caproate
NUI: N0000179012
RxNorm_CUI: 12488
RxNorm_Name: hydroxyprogesterone caproate (USP)
Synonym: 17 alpha-hydroxyprogesterone caproate
Synonym: 17 alpha-hydroxyprogesterone capronate
Synonym: 17 alpha-oxyprogesterone capronate
Synonym: 17-((1-oxohexyl)oxy)pregn-4-ene-3,20-dione
Synonym: 17-hydroxyprogesterone capronate
Synonym: hydroxyprogesterone caproate
Synonym: hydroxyprogesterone hexanoate
Synonym: oxyprogesterone caproate
UMLS_CUI: C0044971
code: CMSHM0074009
imported from: NDF-RT.owl

Benzatropine Methanesulfonate [Chemical/Ingredient]
type: Class
subclass of: Benztropine [Chemical/Ingredient]
Display_Name: Benzatropine Methanesulfonate
MeSH_CUI: M0045522
MeSH_DUI: D001590
MeSH_Name: Benzatropine Methanesulfonate
NUI: N0000179048
RxNorm_CUI: 18927
RxNorm_Name: benztropine mesylate
Synonym: Benzatropine Mesylate
Synonym: Benztropine Mesylate
UMLS_CUI: C0053156
code: CMSHM0045522
imported from: NDF-RT.owl

chloroquine diphosphate [Chemical/Ingredient]
type: Class
subclass of: Chloroquine [Chemical/Ingredient]
Display_Name: chloroquine diphosphate
MeSH_CUI: M0081184
MeSH_DUI: C023676
MeSH_Name: chloroquine diphosphate
NUI: N0000179079
RxNorm_CUI: 20863
RxNorm_Name: chloroquine phosphate
Synonym: N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, phosphate (1:2)
Synonym: arechin
Synonym: chingamin phosphate
Synonym: chloroquine phosphate
Synonym: delagil
Synonym: khingamin phosphate
Synonym: unspecified phosphate of chloroquine diphosphate
UMLS_CUI: C0055447
code: CMSHM0081184
imported from: NDF-RT.owl

Tamoxifen Citrate [Chemical/Ingredient]
type: Class
subclass of: Tamoxifen [Chemical/Ingredient]
Display_Name: Tamoxifen Citrate
MeSH_CUI: M0373246
MeSH_DUI: D013629
MeSH_Name: Tamoxifen Citrate
NUI: N0000179289
RxNorm_CUI: 40137
RxNorm_Name: Tamoxifen Citrate
UMLS_CUI: C0079589
code: CMSHM0373246
imported from: NDF-RT.owl

Toremifene Citrate [Chemical/Ingredient]
type: Class
subclass of: Toremifene [Chemical/Ingredient]
Display_Name: Toremifene Citrate
MeSH_CUI: M0026288
MeSH_DUI: D017312
MeSH_Name: Toremifene Citrate
NUI: N0000179327
RxNorm_CUI: 49953
RxNorm_Name: Toremifene Citrate
Synonym: Toremifene Citrate (1:1)
UMLS_CUI: C0117339
code: CMSHM0026288
imported from: NDF-RT.owl

Thiethylperazine Malate [Chemical/Ingredient]
type: Class
subclass of: Thiethylperazine [Chemical/Ingredient]
Display_Name: Thiethylperazine Malate
MeSH_CUI: M0021337
MeSH_DUI: D013847
MeSH_Name: Thiethylperazine Malate
NUI: N0000179374
RxNorm_CUI: 71529
RxNorm_Name: Thiethylperazine Malate
UMLS_CUI: C0242518
code: CMSHM0021337
imported from: NDF-RT.owl

Clomipramine Hydrochloride [Chemical/Ingredient]
type: Class
subclass of: Clomipramine [Chemical/Ingredient]
Display_Name: Clomipramine Hydrochloride
MeSH_CUI: M0004600
MeSH_DUI: D002997
MeSH_Name: Clomipramine Hydrochloride
NUI: N0000179401
RxNorm_CUI: 81984
RxNorm_Name: Clomipramine Hydrochloride
UMLS_CUI: C0282107
code: CMSHM0004600
imported from: NDF-RT.owl

Chlorpromazine Hydrochloride [Chemical/Ingredient]
type: Class
subclass of: Chlorpromazine [Chemical/Ingredient]
Display_Name: Chlorpromazine Hydrochloride
MeSH_CUI: M0363614
MeSH_DUI: D002746
MeSH_Name: Chlorpromazine Hydrochloride
NUI: N0000179496
RxNorm_CUI: 104728
RxNorm_Name: Chlorpromazine hydrochloride
UMLS_CUI: C0355077
code: CMSHM0363614
imported from: NDF-RT.owl

Hydroxychloroquine Sulfate [Chemical/Ingredient]
type: Class
subclass of: Hydroxychloroquine [Chemical/Ingredient]
Display_Name: Hydroxychloroquine Sulfate
MeSH_CUI: M0330264
MeSH_DUI: D006886
MeSH_Name: Hydroxychloroquine Sulfate
NUI: N0000179552
RxNorm_CUI: 153972
RxNorm_Name: Hydroxychloroquine Sulfate
Synonym: Hydroxychloroquine Sulfate (1:1) Salt
UMLS_CUI: C0596007
code: CMSHM0330264
imported from: NDF-RT.owl

lopinavir [Chemical/Ingredient]
type: Class
subclass of: Pyrimidinones [Chemical/Ingredient]
Display_Name: lopinavir
MeSH_CUI: M0406972
MeSH_DUI: C112035
MeSH_Name: lopinavir
NUI: N0000179581
RxNorm_CUI: 195088
RxNorm_Name: lopinavir
Synonym: N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
UMLS_CUI: C0674432
code: CMSHM0406972
imported from: NDF-RT.owl

Fluphenazine Hydrochloride [Chemical/Ingredient]
type: Class
subclass of: Fluphenazine [Chemical/Ingredient]
Display_Name: Fluphenazine Hydrochloride
MeSH_CUI: M0354107
MeSH_DUI: D005476
MeSH_Name: Fluphenazine Hydrochloride
NUI: N0000179649
RxNorm_CUI: 203207
RxNorm_Name: Fluphenazine Hydrochloride
UMLS_CUI: C0700567
code: CMSHM0354107
imported from: NDF-RT.owl

Nelfinavir Mesylate [Chemical/Ingredient]
type: Class
subclass of: Nelfinavir [Chemical/Ingredient]
Display_Name: Nelfinavir Mesylate
MeSH_CUI: M0329047
MeSH_DUI: D019888
MeSH_Name: Nelfinavir Mesylate
NUI: N0000179715
RxNorm_CUI: 266565
RxNorm_Name: Nelfinavir Mesylate
Synonym: Nelfinavir Monomethane Sulfonate
UMLS_CUI: C0886530
code: CMSHM0329047
imported from: NDF-RT.owl

ciclesonide [Chemical/Ingredient]
type: Class
subclass of: Pregnenediones [Chemical/Ingredient]
Display_Name: ciclesonide
MeSH_CUI: M0332803
MeSH_DUI: C120481
MeSH_Name: ciclesonide
NUI: N0000179737
RxNorm_CUI: 274964
RxNorm_Name: ciclesonide
Synonym: (R)-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate
UMLS_CUI: C0907850
code: CMSHM0332803
imported from: NDF-RT.owl

dalbavancin [Chemical/Ingredient]
type: Class
subclass of: Teicoplanin [Chemical/Ingredient]
Display_Name: dalbavancin
MeSH_CUI: M0443425
MeSH_DUI: C469289
MeSH_Name: dalbavancin
NUI: N0000179772
RxNorm_CUI: 354674
UMLS_CUI: C1172636
code: CMSHM0443425
imported from: NDF-RT.owl

dasatinib [Chemical/Ingredient]
type: Class
subclass of: Pyrimidines [Chemical/Ingredient]
subclass of: Thiazoles [Chemical/Ingredient]
Display_Name: dasatinib
MeSH_CUI: M0470497
MeSH_DUI: C488369
MeSH_Name: dasatinib
NUI: N0000179780
RxNorm_CUI: 475342
RxNorm_Name: dasatinib
Synonym: N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide
UMLS_CUI: C1455147
code: CMSHM0470497
imported from: NDF-RT.owl

eltrombopag [Chemical/Ingredient]
type: Class
subclass of: Pyrazoles [Chemical/Ingredient]
subclass of: Benzoic Acids [Chemical/Ingredient]
subclass of: Hydrazines [Chemical/Ingredient]
Display_Name: eltrombopag
MeSH_CUI: M0511065
MeSH_DUI: C520809
MeSH_Name: eltrombopag
NUI: N0000179799
RxNorm_CUI: 711942
RxNorm_Name: eltrombopag
UMLS_CUI: C1831905
code: CMSHM0511065
imported from: NDF-RT.owl

BAICALIN
type: Class
subclass of: B [Preparations]
type: NamedIndividual
Display_Name: BAICALIN
Level: Ingredient
NUI: N0000179808
RxNorm_CUI: 18737
Status: Active
UMLS_CUI: C0052929
VANDF_Record: <VANDF_Record>50.416^4615^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4615</VA_IEN>
VUID: 4028922
code: C50.416^4615^
imported from: NDF-RT.owl

TELAVANCIN
type: Class
subclass of: T [Preparations]
type: NamedIndividual
Display_Name: TELAVANCIN
Level: Ingredient
NUI: N0000180310
RxNorm_CUI: 473837
RxNorm_Name: telavancin
Status: Active
UMLS_CUI: C1453642
VANDF_Record: <VANDF_Record>50.416^4662^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4662</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4531^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4531</VA_IEN>
VUID: 4029465
code: C50.416^4662^
imported from: NDF-RT.owl

TOCILIZUMAB
type: Class
subclass of: T [Preparations]
type: NamedIndividual
Display_Name: TOCILIZUMAB
Level: Ingredient
NUI: N0000180629
RxNorm_CUI: 612865
RxNorm_Name: tocilizumab
Status: Active
UMLS_CUI: C1609165
VANDF_Record: <VANDF_Record>50.416^4670^</VANDF_Record><VA_File>50.416</VA_File><VA_IEN>4670</VA_IEN>
VANDF_Record: <VANDF_Record>50.6^4548^</VANDF_Record><VA_File>50.6</VA_File><VA_IEN>4548</VA_IEN>
VUID: 4029705
code: C50.416^4670^
imported from: NDF-RT.owl

Leukoencephalopathies [Disease/Finding]
type: Class
subclass of: Brain Diseases [Disease/Finding]
Display_Name: Leukoencephalopathies
MeSH_CUI: M0529130
MeSH_DUI: D056784
MeSH_Definition: Any of various diseases affecting the white matter of the central nervous system.
MeSH_Name: Leukoencephalopathies
NUI: N0000181110
RxNorm_CUI: 1023470
Synonym: Leukoencephalopathy
Synonym: White Matter Diseases
UMLS_CUI: C0270612
code: CMSHM0529130
imported from: NDF-RT.owl

Cardiovascular Infections [Disease/Finding]
type: Class
subclass of: Cardiovascular Diseases [Disease/Finding]
subclass of: Infection [Disease/Finding]
Display_Name: Cardiovascular Infections
MeSH_CUI: M0496690
MeSH_DUI: D053821
MeSH_Definition: Pathological conditions of the CARDIOVASCULAR SYSTEM caused by infections.
MeSH_Name: Cardiovascular Infections
NUI: N0000181166
RxNorm_CUI: 1021827
Synonym: Infections, Cardiovascular
UMLS_CUI: C0596270
code: CMSHM0496690
imported from: NDF-RT.owl

Female Urogenital Diseases [Disease/Finding]
type: Class
subclass of: Female Urogenital Diseases and Pregnancy Complications [Disease/Finding]
Display_Name: Female Urogenital Diseases
MeSH_CUI: M0489295
MeSH_DUI: D052776
MeSH_Definition: Pathological processes of the female URINARY TRACT and the reproductive system (GENITALIA, FEMALE).
MeSH_Name: Female Urogenital Diseases
NUI: N0000181236
RxNorm_CUI: 1024696
Synonym: Female Genitourinary Diseases
UMLS_CUI: C1720887
code: CMSHM0489295
imported from: NDF-RT.owl

Neoplasms, Plasma Cell [Disease/Finding]
type: Class
subclass of: Neoplasms by Histologic Type [Disease/Finding]
Display_Name: Neoplasms, Plasma Cell
MeSH_CUI: M0502872
MeSH_DUI: D054219
MeSH_Definition: Neoplasms associated with a proliferation of a single clone of PLASMA CELLS and characterized by the secretion of PARAPROTEINS.
MeSH_Name: Neoplasms, Plasma Cell
NUI: N0000181264
RxNorm_CUI: 1005768
Synonym: Plasma Cell Neoplasms
UMLS_CUI: C1959632
code: CMSHM0502872
imported from: NDF-RT.owl

Proteostasis Deficiencies [Disease/Finding]
type: Class
subclass of: Metabolic Diseases [Disease/Finding]
Display_Name: Proteostasis Deficiencies
MeSH_CUI: M0534903
MeSH_DUI: D057165
MeSH_Definition: Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins.
MeSH_Name: Proteostasis Deficiencies
NUI: N0000181302
RxNorm_CUI: 1002154
Synonym: Proteostasis Dysfunctions
UMLS_CUI: C2718000
code: CMSHM0534903
imported from: NDF-RT.owl

epidemic model
type: Class
subclass of: disease transmission model
definition: A disease transmission model whose concretization is realized as a simulation of infectious disease epidemic or infectious disease pandemic.
definition editor: William Hogan and Michael Wagner
imported from: apollo sv.owl
elucidation: An algorithm the concretizations of which models the transmission of transmissible disease.

infectious disease control objective specification
type: Class
subclass of: IAO_0000005
definition: An objective specification that is realized by processes that are able or likely to stop the spread of a disease in a population.
imported from: apollo sv.owl
elucidation: an objective of achieving satisfactory control of epidemic spread through a population
comment: typically, the process endpoint is achievement of R0 < 1

infectious disease control strategy
type: Class
equivalent class: Class
  intersection of: IAO_0000104
  intersection of: Restriction
    on property: has part
    some values from: infectious disease control objective specification
subclass of: IAO_0000104
definition: A plan specification whose objective specification is an infectious disease control objective specification.
imported from: apollo sv.owl
elucidation: A plan with the goal of preventing or mitigating the effects of infections in a population due to one or more pathogens.
Unique Apollo Label: InfectiousDiseaseControlMeasure
comment: The essential goal of an infectious disease control strategy is to protect the susceptible organisms in a population.

school closure control strategy
type: Class
subclass of: place closure control strategy
definition: A place closure control strategy whose action specification is realized in a school closure process.
imported from: apollo sv.owl
elucidation: A control measure in which schools are closed in an attempt to reduce transmission of disease.
Unique Apollo Label: SchoolClosureControlStrategy

disease transmission model
type: Class
subclass of: IAO_0000064
definition: An algorithm that models the progress of a transmissible disease in a population.
imported from: apollo sv.owl
elucidation: An algorithm that models the progress of a transmissible disease in a population.
Unique Apollo Label: disease transmission model

transmission coefficient
type: Class
subclass of: OBI_0001554
definition: An information content entity that represents the rate that an infection moves from infected individuals to susceptible individuals in a population.
imported from: apollo sv.owl
elucidation: An information content entity that represents the rate that an infection moves from infected individuals to susceptible individuals in a population.
Unique Apollo Label: beta

place closure control strategy
type: Class
subclass of: infectious disease control strategy
definition: an infectious disease control strategy that has an action specification that is realized in closing facilities where organisms congregate during times when the facilities normally would be open.
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An infectious disease control strategy that attempts to prevent infection of susceptible host organisms in a population by preventing potentially infectious contacts (for a particular pathogen) among the organisms in the population.
Unique Apollo Label: PlaceClosureControlMeasure

case isolation control strategy
type: Class
subclass of: infectious disease control strategy
definition: an infectious disease control strategy that has an action specification that is realized in isolating organsims who are infectious.
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An infectious disease control strategy that isolates infected and/or infectious individuals in a population from most or all potentially infectious contacts with susceptible individuals.
Unique Apollo Label: CaseQuarantineControlMeasure

close individual places independently strategy
type: Class
subclass of: place closure control strategy
definition: A place-closure control strategy that decides on a case-by-case basis whether to close places of a certain type, as opposed to blanket policy that closes all places of a certain type at the same time.
imported from: apollo sv.owl
elucidation: A place-closure control strategy that decides on a case-by-case basis whether to close places of a certain type, as opposed to blanket policy that closes all places of a certain type at the same time.
Unique Apollo Label: closeIndividualPlacesIndependently

agent-based disease transmission model
type: Class
subclass of: disease transmission model
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A disease transmission model that explicitly represents each individual in the population and simulates the acquisition of disease by individuals who do not already have it at simulator time zero.

compartmental disease transmission model
type: Class
subclass of: disease transmission model
imported from: apollo sv.owl
elucidation: A disease transmission model that represents populations of susceptible and infected individuals (but not these individuals directly themselves) and simulates movement of individuals from one such population (a.k.a. compartment) to another.

voluntary household quarantine control strategy
type: Class
subclass of: infectious disease control strategy
definition: An infectious disease control strategy whereby the household members of infectious indivduals voluntarily stay at home to avoid further potentially infectious contacts.
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An infectious disease control strategy whereby the household members of infectious indivduals voluntarily stay at home to avoid further potentially infectious contacts.
Unique Apollo Label: VoluntaryHouseholdQuarantineControlMeasure

quarantine control strategy
type: Class
subclass of: infectious disease control strategy
editor preferred label: quarantine control strategy
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An infectious disease control strategy whereby organisms who have had contact with infectious organisms but are not symptomatic or otherwise known to be infectious are prevented from having contact with other susceptible organisms.

leakage rate of Wolbachia infection in mosquito population infected with Wolbachia
type: Class
subclass of: OBI_0001554
definition: The rate at which offspring of the Wolbachia-infected female mosquito subpopulation (of the overall mosquito population) are not infected with Wolbachia.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: The rate at which offspring of the Wolbachia-infected female mosquito subpopulation (of the overall mosquito population) are not infected with Wolbachia.
Unique Apollo Label: wolbachiaEffectOnLeakageRate

transmission rate of pathogen to human from Wolbachia-infected mosquito bites
type: Class
subclass of: OBI_0001554
definition: The rate at which bites of mosquitoes infected with both Wolbachia and a particular pathogen such as dengue result in an infection in a susceptible human host.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: The rate at which bites of mosquitoes infected with both Wolbachia and a particular pathogen such as dengue result in an infection in a susceptible human host.
Unique Apollo Label: wolbachiaEffectOnVectorialCapacity

migration speed
type: Class
subclass of: OBI_0001554
definition: A rate measurement datum of that divides the total distance traveled during some migration process by the duration of the temporal interval occupied by that process.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A rate measurement datum of that divides the total distance traveled during some migration process by the duration of the temporal interval occupied by that process.
Unique Apollo Label: migrationSpeed

movement speed
type: Class
subclass of: OBI_0001554
definition: A rate measurement datum that specifies the ratio of distance travelled during a movement process to the duration of the time interval occupied by the process.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A rate measurement datum that specifies the ratio of distance travelled during a movement process to the duration of the time interval occupied by the process.
Unique Apollo Label: speedOfMovement

mortality rate
type: Class
subclass of: OBI_0001554
definition: A rate measurement datum that specifies the percentage of organisms within a population that have died over a given time interval.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A rate measurement datum that specifies the percentage of organisms within a population that have died over a given time interval.
Unique Apollo Label: mortalityRate

age-dependent fecundity reduction
type: Class
subclass of: OBI_0001554
definition: A rate measurement datum that measures the percentage decrease per unit time (typically per day) in the number of offspring to which a female mosquito passes an infection with a particular pathogen (e.g., Wolbachia).
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A rate measurement datum that measures the percentage decrease per unit time (typically per day) in the number of offspring to which a female mosquito passes an infection with a particular pathogen (e.g., Wolbachia).
Unique Apollo Label: ageDependentFecundityReduction

travel-related infectious disease control strategy
type: Class
subclass of: infectious disease control strategy
editor preferred label: infectious disease control strategy to prevent infection acquisition by individuals traveling from one ecosystem to another ecosystem
definition: An infectious disease control strategy that has an objective specification of preventing infection acquisition by organisms traveling from one ecosystem to another ecosystem.
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An infectious disease control strategy that has an objective specification of preventing infection acquisition by organisms traveling from one ecosystem to another ecosystem.

contact isolation control measure
type: Class
subclass of: case isolation control strategy
definition: A case isolation control measure that has an action specification that is realized in preventing one or more infectious organisms from having physical contact with other organisms.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A case isolation control measure that has an action specification that is realized in preventing one or more infectious organisms from having physical contact with other organisms.
Unique Apollo Label: ContactIsolationControlMeasure

rate of hydrological precipitation
type: Class
subclass of: OBI_0001554
definition: A rate measurement datum that is the result of the measurement of the volume of water produced by some hydrological precipitation process at a particular geographical region divided by the number of temporal intervals of equal duration over which the precipitation occurred.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl

scale-free network model
type: Class
subclass of: IAO_0000064
definition: An algorithm that models some scale-free network.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl

disease surveillance objective specification
type: Class
subclass of: IAO_0000005
editor preferred label: disease surveillance objective specification
definition: An objective specification whose endpoint is human awareness of the level of a particular disease in a particular population of a given biological taxon during some time interval.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: An objective specification whose endpoint is human awareness of the level of a particular disease in a particular population of a given biological taxon during some time interval.

Susceptible-Infected-Susceptible model
type: Class
subclass of: compartmental disease transmission model
definition: A compartmental disease transmission model that represents some infection in ecosystem in which there is only a susceptible population and an infectious population, such that individuals who aren't infectious are susceptible.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A compartmental disease transmission model that represents some infection in ecosystem in which there is only a susceptible population and an infectious population, such that individuals who aren't infectious are susceptible.

Susceptible-Infected-Resistant model
type: Class
subclass of: compartmental disease transmission model
definition: A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, infectious individuals, and recovered individuals, such that recovered individuals are immune to future infection.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, infectious individuals, and recovered individuals, such that recovered individuals are immune to future infection.

Susceptible-Exposed-Infectious-Recovered model
type: Class
subclass of: compartmental disease transmission model
definition: A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, exposed individuals, infectious individuals, and immune inviduals, such that exposed individuals are infected but cannot transmit the pathogen.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, exposed individuals, infectious individuals, and immune inviduals, such that exposed individuals are infected but cannot transmit the pathogen.

metapopulation disease transmission model
type: Class
subclass of: disease transmission model
definition: A disease transmission model that is about two or more collections of organisms of a particular biological taxon in separate geographical locations and some geographical migration of organisms between them.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A disease transmission model that is about two or more collections of organisms of a particular biological taxon in separate geographical locations and some geographical migration of organisms between them.

two-strain Susceptible-Infectious-Resistant model
type: Class
subclass of: Susceptible-Infected-Resistant model
definition: A Susceptible-Infected-Resistant model that represents exactly two infections in ecosystem by exactly two pathogens.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl
elucidation: A Susceptible-Infected-Resistant model that represents exactly two infections in ecosystem by exactly two pathogens.

infectious disease forecast objective specification
type: Class
subclass of: IAO_0000005
definition: An objective specification that is realized by the estimation of one or more predicted data items that are about 1) some infection in ecosystem and 2) potential changes to its number of participants (e.g., individuals within a host population, individuals within a vector population) relative to a particular temporal region; and is part of some infectious disease forecasting software.
definition editor: Matthew Diller
definition editor: William R. Hogan
imported from: apollo sv.owl

entity
type: Class
subclass of: Thing
BFO OWL specification label: entity
BFO CLIF specification label: Entity
editor preferred label: entity
example of usage: Julius Caesar
example of usage: Verdi’s Requiem
example of usage: the Second World War
example of usage: your body mass index
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
imported from: apollo sv.owl
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: iao.owl
imported from: ico.owl
imported from: ido.owl
imported from: mondo.owl
imported from: oae.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: vo.owl
elucidation: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

continuant
type: Class
subclass of: entity
BFO OWL specification label: continuant
BFO CLIF specification label: Continuant
editor preferred label: continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
imported from: apollo sv.owl
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: iao.owl
imported from: ido.owl
imported from: oae.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: pato.owl
imported from: ro.owl
imported from: vo.owl
elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has associated axiom(nl): if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has associated axiom(nl): if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has associated axiom(nl): if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has associated axiom(fol): (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has associated axiom(fol): (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

occurrent
type: Class
subclass of: entity
BFO OWL specification label: occurrent
BFO CLIF specification label: Occurrent
editor preferred label: occurrent
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
editor note: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
editor note: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
imported from: apollo sv.owl
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: iao.owl
imported from: ico.owl
imported from: ido.owl
imported from: oae.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: ro.owl
imported from: vo.owl
elucidation: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has associated axiom(nl): Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has associated axiom(nl): b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has associated axiom(fol): (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has associated axiom(fol): (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]

independent continuant
type: Class
subclass of: continuant
BFO OWL specification label: ic
BFO CLIF specification label: IndependentContinuant
example of usage: a chair
example of usage: a heart
example of usage: a leg
example of usage: a molecule
example of usage: a spatial region
example of usage: an atom
example of usage: an orchestra.
example of usage: an organism
example of usage: the bottom right portion of a human torso
example of usage: the interior of your mouth
definition: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: iao.owl
imported from: ido.owl
imported from: oae.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: ro.owl
imported from: vo.owl
has associated axiom(nl): For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has associated axiom(nl): For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has associated axiom(fol): (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has associated axiom(fol): (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has associated axiom(fol): (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.

spatial region
type: Class
subclass of: immaterial entity
BFO OWL specification label: s-region
BFO CLIF specification label: SpatialRegion
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl
elucidation: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has associated axiom(nl): All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has associated axiom(fol): (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has associated axiom(fol): (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]

temporal region
type: Class
subclass of: occurrent
BFO OWL specification label: t-region
BFO CLIF specification label: TemporalRegion
editor note: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: opmi.owl
elucidation: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has associated axiom(nl): All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
has associated axiom(nl): Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
has associated axiom(fol): (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has associated axiom(fol): (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
has associated axiom(fol): (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]

spatiotemporal region
type: Class
subclass of: occurrent
BFO OWL specification label: st-region
BFO CLIF specification label: SpatiotemporalRegion
example of usage: the spatiotemporal region occupied by a human life
example of usage: the spatiotemporal region occupied by a process of cellular meiosis.
example of usage: the spatiotemporal region occupied by the development of a cancer tumor
imported from: ogg.owl
elucidation: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has associated axiom(nl): All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has associated axiom(nl): Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has associated axiom(nl): Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has associated axiom(nl): Every spatiotemporal region occupies_spatiotemporal_region itself.
has associated axiom(nl): Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
has associated axiom(fol): (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has associated axiom(fol): (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
has associated axiom(fol): (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]

process
type: Class
subclass of: occurrent
BFO OWL specification label: process
BFO CLIF specification label: Process
editor preferred label: process
example of usage: a process of cell-division, \ a beating of the heart
example of usage: a process of meiosis
example of usage: a process of sleeping
example of usage: the course of a disease
example of usage: the flight of a bird
example of usage: the life of an organism
example of usage: your process of aging.
definition: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: iao.owl
imported from: ico.owl
imported from: ido.owl
imported from: oae.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: ro.owl
imported from: vo.owl
has associated axiom(fol): (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.

disposition
type: Class
subclass of: realizable entity
BFO OWL specification label: disposition
BFO CLIF specification label: Disposition
editor preferred label: disposition
example of usage: an atom of element X has the disposition to decay to an atom of element Y
example of usage: certain people have a predisposition to colon cancer
example of usage: children are innately disposed to categorize objects in certain ways.
example of usage: the cell wall is disposed to filter chemicals in endocitosis and exocitosis
example of usage: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type [89
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
imported from: dron.owl
imported from: ido.owl
imported from: obcs.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl
elucidation: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has associated axiom(nl): If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has associated axiom(fol): (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has associated axiom(fol): (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]

realizable entity
type: Class
subclass of: specifically dependent continuant
BFO OWL specification label: realizable
BFO CLIF specification label: RealizableEntity
editor preferred label: realizable entity
example of usage: the disposition of this piece of metal to conduct electricity.
example of usage: the disposition of your blood to coagulate
example of usage: the function of your reproductive organs
example of usage: the role of being a doctor
example of usage: the role of this boundary to delineate where Utah and Colorado meet
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
imported from: apollo sv.owl
imported from: dron.owl
imported from: envo.owl
imported from: ido.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: vo.owl
elucidation: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has associated axiom(nl): All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has associated axiom(fol): (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has associated axiom(fol): (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]

quality
type: Class
subclass of: specifically dependent continuant
BFO OWL specification label: quality
BFO CLIF specification label: Quality
editor preferred label: quality
example of usage: the ambient temperature of this portion of air
example of usage: the color of a tomato
example of usage: the length of the circumference of your waist
example of usage: the mass of this piece of gold.
example of usage: the shape of your nose
example of usage: the shape of your nostril
imported from: dron.owl
imported from: envo.owl
imported from: obi.owl
imported from: ogg.owl
imported from: pato.owl
imported from: vo.owl
elucidation: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has associated axiom(nl): If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has associated axiom(fol): (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has associated axiom(fol): (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]

specifically dependent continuant
type: Class
subclass of: continuant
BFO OWL specification label: sdc
BFO CLIF specification label: SpecificallyDependentContinuant
editor preferred label: specifically dependent continuant
example of usage: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
example of usage: of one-sided specifically dependent continuants: the mass of this tomato
example of usage: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
example of usage: the disposition of this fish to decay
example of usage: the function of this heart: to pump blood
example of usage: the mutual dependence of proton donors and acceptors in chemical reactions [79
example of usage: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
example of usage: the pink color of a medium rare piece of grilled filet mignon at its center
example of usage: the role of being a doctor
example of usage: the shape of this hole.
example of usage: the smell of this portion of mozzarella
definition: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
definition: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
editor note: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
imported from: apollo sv.owl
imported from: bfo.owl
imported from: dron.owl
imported from: envo.owl
imported from: ido.owl
imported from: oae.owl
imported from: obcs.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: ogms.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: pato.owl
imported from: ro.owl
imported from: vo.owl
has associated axiom(fol): (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
has associated axiom(fol): (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.

role
type: Class
subclass of: realizable entity
BFO OWL specification label: role
BFO CLIF specification label: Role
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: the priest role
example of usage: the role of a boundary to demarcate two neighboring administrative territories
example of usage: the role of a building in serving as a military target
example of usage: the role of a stone in marking a property boundary
example of usage: the role of subject in a clinical trial
example of usage: the student role
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
imported from: dron.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: vo.owl
elucidation: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has associated axiom(fol): (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]

fiat object
type: Class
subclass of: material entity
imported from: envo.owl
label: fiat object part

object aggregate
type: Class
subclass of: material entity
BFO OWL specification label: object-aggregate
BFO CLIF specification label: ObjectAggregate
example of usage: a collection of cells in a blood biobank.
example of usage: a swarm of bees is an aggregate of members who are linked together through natural bonds
example of usage: a symphony orchestra
example of usage: an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)
example of usage: defined by fiat: the aggregate of members of an organization
example of usage: defined through physical attachment: the aggregate of atoms in a lump of granite
example of usage: defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container
example of usage: defined via attributive delimitations such as: the patients in this hospital
example of usage: the aggregate of bearings in a constant velocity axle joint
example of usage: the aggregate of blood cells in your body
example of usage: the nitrogen atoms in the atmosphere
example of usage: the restaurants in Palo Alto
example of usage: your collection of Meissen ceramic plates.
editor note: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
editor note: BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).
definition source: ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
imported from: dron.owl
elucidation: b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
has associated axiom(fol): (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]

three-dimensional spatial region
type: Class
subclass of: spatial region
BFO OWL specification label: 3d-s-region
BFO CLIF specification label: ThreeDimensionalSpatialRegion
example of usage: a cube-shaped region of space
example of usage: a sphere-shaped region of space,
imported from: ogg.owl
elucidation: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
has associated axiom(fol): (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]

site
type: Class
subclass of: independent continuant
subclass of: immaterial entity
BFO OWL specification label: site
BFO CLIF specification label: Site
example of usage: Manhattan Canyon)
example of usage: a hole in the interior of a portion of cheese
example of usage: a rabbit hole
example of usage: an air traffic control region defined in the airspace above an airport
example of usage: the Grand Canyon
example of usage: the Piazza San Marco
example of usage: the cockpit of an aircraft
example of usage: the hold of a ship
example of usage: the interior of a kangaroo pouch
example of usage: the interior of the trunk of your car
example of usage: the interior of your bedroom
example of usage: the interior of your office
example of usage: the interior of your refrigerator
example of usage: the lumen of your gut
example of usage: your left nostril (a fiat part – the opening – of your left nasal cavity)
imported from: envo.owl
imported from: iao.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: vo.owl
elucidation: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
has associated axiom(fol): (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]

object
type: Class
subclass of: material entity
BFO OWL specification label: object
BFO CLIF specification label: Object
example of usage: atom
example of usage: cell
example of usage: cells and organisms
example of usage: engineered artifacts
example of usage: grain of sand
example of usage: molecule
example of usage: organelle
example of usage: organism
example of usage: planet
example of usage: solid portions of matter
example of usage: star
editor note: BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.
editor note: BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).
editor note: BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47
editor note: BFO 2 Reference: an object is a maximal causally unified material entity
editor note: BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74
imported from: dron.owl
imported from: envo.owl
elucidation: b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])

generically dependent continuant
type: Class
subclass of: continuant
BFO OWL specification label: gdc
BFO CLIF specification label: GenericallyDependentContinuant
editor preferred label: generically dependent continuant
example of usage: The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
example of usage: the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
example of usage: the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
definition: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
definition: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
imported from: dron.owl
imported from: envo.owl
imported from: obcs.owl
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl
has associated axiom(fol): (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
comment: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.

function
type: Class
subclass of: disposition
subclass of: realizable entity
BFO OWL specification label: function
BFO CLIF specification label: Function
example of usage: the function of a hammer to drive in nails
example of usage: the function of a heart pacemaker to regulate the beating of a heart through electricity
example of usage: the function of amylase in saliva to break down starch into sugar
editor note: BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.
imported from: dron.owl
imported from: obi.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: vo.owl
elucidation: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has associated axiom(fol): (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]

process boundary
type: Class
subclass of: occurrent
BFO OWL specification label: p-boundary
BFO CLIF specification label: ProcessBoundary
example of usage: the boundary between the 2nd and 3rd year of your life.
definition: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
imported from: ogg.owl
has associated axiom(nl): Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
has associated axiom(fol): (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has associated axiom(fol): (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]

one-dimensional temporal region
type: Class
subclass of: temporal region
BFO OWL specification label: 1d-t-region
BFO CLIF specification label: OneDimensionalTemporalRegion
example of usage: the temporal region during which a process occurs.
editor note: BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).
imported from: obi.owl
imported from: obib.owl
imported from: opmi.owl
elucidation: A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])
has associated axiom(fol): (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001]

material entity
type: Class
subclass of: independent continuant
BFO OWL specification label: material
BFO CLIF specification label: MaterialEntity
editor preferred label: material entity
example of usage: a flame
example of usage: a forest fire
example of usage: a human being
example of usage: a hurricane
example of usage: a photon
example of usage: a puff of smoke
example of usage: a sea wave
example of usage: a tornado
example of usage: an aggregate of human beings.
example of usage: an energy wave
example of usage: an epidemic
example of usage: the undetached arm of a human being
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
imported from: bfo.owl
imported from: cl.owl
imported from: dron.owl
imported from: envo.owl
imported from: ido.owl
imported from: oae.owl
imported from: obi.owl
imported from: obib.owl
imported from: ogg.owl
imported from: omrse.owl
imported from: opmi.owl
imported from: uberon.owl
imported from: vo.owl
elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has associated axiom(nl): Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has associated axiom(nl): every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has associated axiom(fol): (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

immaterial entity
type: Class
subclass of: independent continuant
BFO OWL specification label: immaterial
BFO CLIF specification label: ImmaterialEntity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10
imported from: obi.owl
imported from: ogg.owl
imported from: vo.owl

process profile
type: Class
subclass of: process
BFO OWL specification label: process-profile
BFO CLIF specification label: ProcessProfile
example of usage: On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels
example of usage: One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.
example of usage: The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.
definition: b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
imported from: obi.owl
elucidation: b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])
has associated axiom(fol): (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005]
has associated axiom(fol): (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002]

zero-dimensional temporal region
type: Class
subclass of: temporal region
BFO OWL specification label: 0d-t-region
BFO CLIF specification label: ZeroDimensionalTemporalRegion
example of usage: a temporal region that is occupied by a process boundary
example of usage: right now
example of usage: the moment at which a child is born
example of usage: the moment at which a finger is detached in an industrial accident
example of usage: the moment of death.
alternative term: temporal instant.
imported from: obi.owl
imported from: ogg.owl
imported from: opmi.owl
elucidation: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
has associated axiom(fol): (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]

aloxistatin
type: Class
subclass of: ethyl ester
subclass of: L-leucine derivative
subclass of: monocarboxylic acid amide
subclass of: epoxide
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64932
definition: An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylbutyl)-L-leucinamide.
definition source: PMID: 32142651
imported from: chebi.owl
charge: 0
formula: C17H30N2O5
inchi: InChI=1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1
inchikey: SRVFFFJZQVENJC-IHRRRGAJSA-N
mass: 342.431
monoisotopicmass: 342.21547
database_cross_reference: Beilstein:5354546
database_cross_reference: CAS:88321-09-9
database_cross_reference: PMID:26388830
database_cross_reference: Reaxys:5354546
has exact synonym: ethyl (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylate
has_obo_namespace: chebi_ontology
has_related_synonym: E 64d
has_related_synonym: E-64d
has_related_synonym: E64d
has_related_synonym: Ethyl (+)-(2S,3S)-2,3-epoxy-N-((S)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate
has_related_synonym: Loxistatin
has_related_synonym: aloxistatin
has_related_synonym: aloxistatina
has_related_synonym: aloxistatine
has_related_synonym: aloxistatinum
id: CHEBI:101381
in subset: 3 STAR

electron
type: Class
subclass of: CHEBI_36338
definition: Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
imported from: chebi.owl
charge: -1
mass: 0.000548579903
monoisotopicmass: 0.0
database_cross_reference: KEGG:C05359
database_cross_reference: PMID:21614077
database_cross_reference: Wikipedia:Electron
has exact synonym: electron
has_obo_namespace: chebi_ontology
has_related_synonym: Elektron
has_related_synonym: beta
has_related_synonym: beta(-)
has_related_synonym: beta-particle
has_related_synonym: e
has_related_synonym: e(-)
has_related_synonym: e-
has_related_synonym: negatron
id: CHEBI:10545
in subset: 3 STAR

N-[4-[[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-trioxo-1,3-diazinan-5-ylidene]methylamino]phenyl]acetamide
type: Class
subclass of: anilide
subclass of: acetamides
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000009022
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 10878288
imported from: chebi.owl
charge: 0
formula: C23H24N4O6
inchi: InChI=1S/C23H24N4O6/c1-14(28)25-17-7-5-16(6-8-17)24-13-18-21(29)26-23(31)27(22(18)30)11-10-15-4-9-19(32-2)20(12-15)33-3/h4-9,12-13,24H,10-11H2,1-3H3,(H,25,28)(H,26,29,31)
inchikey: YIYRLFJOQLGDMQ-UHFFFAOYSA-N
mass: 452.461
monoisotopicmass: 452.16958
database_cross_reference: LINCS:LSM-16879
has_obo_namespace: chebi_ontology
id: CHEBI:105516
in subset: 2 STAR

(3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one
type: Class
subclass of: biphenyls
subclass of: Restriction
  on property: chemical has protein target as agonist
  some values from: PR_000011650
subclass of: Restriction
  on property: chemical has protein target as agonist
  some values from: PR_000032038
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48705
definition source: Reference: PMID: 12213263
imported from: chebi.owl
charge: 0
formula: C30H31FN2O
inchi: InChI=1S/C30H31FN2O/c1-20-8-7-11-26-28(20)30(34)33(19-21-9-5-4-6-10-21)29(26)25-17-14-23(18-27(25)31)22-12-15-24(16-13-22)32(2)3/h4-7,9-18,20,26,28-29H,8,19H2,1-3H3/t20-,26+,28+,29+/m1/s1
inchikey: OGOYFYBJGOZDCJ-SZOMIKIBSA-N
mass: 454.579
monoisotopicmass: 454.24204
database_cross_reference: LINCS:LSM-18786
has_obo_namespace: chebi_ontology
id: CHEBI:107432
in subset: 2 STAR

1,3-dimethyl-8-(4-phenyl-1-piperazinyl)-7H-purine-2,6-dione
type: Class
subclass of: piperazines
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: GO_0006412
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 29526098
imported from: chebi.owl
charge: 0
formula: C17H20N6O2
inchi: InChI=1S/C17H20N6O2/c1-20-14-13(15(24)21(2)17(20)25)18-16(19-14)23-10-8-22(9-11-23)12-6-4-3-5-7-12/h3-7H,8-11H2,1-2H3,(H,18,19)
inchikey: CYQZBNXFVGWVOS-UHFFFAOYSA-N
mass: 340.380
monoisotopicmass: 340.16477
database_cross_reference: LINCS:LSM-19603
has_obo_namespace: chebi_ontology
id: CHEBI:108226
in subset: 2 STAR

2-fluoro-N-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-phenyl-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-2-yl]methyl]-N-methylbenzamide
type: Class
subclass of: CHEBI_38193
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 31969702
imported from: chebi.owl
charge: 0
formula: C28H30FN3O4
inchi: InChI=1S/C28H30FN3O4/c1-18-15-32(19(2)17-33)28(35)23-13-21(20-9-5-4-6-10-20)14-30-26(23)36-25(18)16-31(3)27(34)22-11-7-8-12-24(22)29/h4-14,18-19,25,33H,15-17H2,1-3H3/t18-,19+,25+/m0/s1
inchikey: LKWROLXNVKNHNW-OSWQYVSFSA-N
mass: 491.555
monoisotopicmass: 491.22203
database_cross_reference: LINCS:LSM-21396
has_obo_namespace: chebi_ontology
id: CHEBI:109969
in subset: 2 STAR

(S)-carnitine
type: Class
subclass of: carnitine
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_51453
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-carnitine
definition: The (S)-enantiomer of carnitine.
imported from: chebi.owl
charge: 0
formula: C7H15NO3
inchi: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m0/s1
inchikey: PHIQHXFUZVPYII-LURJTMIESA-N
mass: 161.19894
monoisotopicmass: 161.10519
smiles: C[N+](C)(C)C[C@@H](O)CC([O-])=O
database_cross_reference: Beilstein:4292316
database_cross_reference: CAS:541-14-0
database_cross_reference: KEGG:C15025
has exact synonym: (3S)-3-hydroxy-4-(trimethylammonio)butanoate
has exact synonym: (S)-Carnitine
has exact synonym: (S)-carnitine
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-Carnitine
has_related_synonym: Carnitine D-form
has_related_synonym: D-(3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide, inner salt
has_related_synonym: D-Carnitine
has_related_synonym: d-Carnitine
id: CHEBI:11060
in subset: 3 STAR

EC 2.1.1.8 (histamine N-methyltransferase) inhibitor
type: Class
subclass of: CHEBI_76871
definition: An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8).
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: EC 2.1.1.8 (histamine N-methyltransferase) inhibitors
has_related_synonym: EC 2.1.1.8 inhibitor
has_related_synonym: EC 2.1.1.8 inhibitors
has_related_synonym: S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitor
has_related_synonym: S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitors
has_related_synonym: S-adenosylmethionine-histamine N-methyltransferase inhibitor
has_related_synonym: S-adenosylmethionine-histamine N-methyltransferase inhibitors
has_related_synonym: histamine 1-methyltransferase inhibitor
has_related_synonym: histamine 1-methyltransferase inhibitors
has_related_synonym: histamine methyltransferase inhibitor
has_related_synonym: histamine methyltransferase inhibitors
has_related_synonym: histamine-methylating enzyme inhibitor
has_related_synonym: histamine-methylating enzyme inhibitors
has_related_synonym: imidazolemethyltransferase inhibitor
has_related_synonym: imidazolemethyltransferase inhibitors
id: CHEBI:110725
in subset: 3 STAR

thymoquinone
type: Class
subclass of: 1,4-benzoquinones
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: antidepressant
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_60809
subclass of: Restriction
  on property: has role
  some values from: CHEBI_67079
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77307
definition: A member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity.
imported from: chebi.owl
charge: 0
formula: C10H12O2
inchi: InChI=1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3
inchikey: KEQHJBNSCLWCAE-UHFFFAOYSA-N
mass: 164.204
monoisotopicmass: 164.08373
smiles: CC(C)C1=CC(=O)C(C)=CC1=O
database_cross_reference: CAS:490-91-5
database_cross_reference: FooDB:FDB013274
database_cross_reference: HMDB:HMDB0034732
database_cross_reference: KNApSAcK:C00010876
database_cross_reference: LINCS:LSM-24947
database_cross_reference: PDBeChem:IMW
database_cross_reference: PMID:23135290
database_cross_reference: PMID:29519737
database_cross_reference: PMID:30422744
database_cross_reference: PMID:32074066
database_cross_reference: PMID:32133061
database_cross_reference: PMID:32560283
database_cross_reference: PMID:32588453
database_cross_reference: PMID:32596711
database_cross_reference: PMID:32608003
database_cross_reference: PMID:32610056
database_cross_reference: PMID:32618005
database_cross_reference: PMID:32620860
database_cross_reference: PMID:32637881
database_cross_reference: PMID:32652915
database_cross_reference: PMID:32767958
database_cross_reference: PMID:32774669
database_cross_reference: PMID:32774804
database_cross_reference: PMID:32793594
database_cross_reference: PMID:32843585
database_cross_reference: PMID:32860490
database_cross_reference: PMID:32867015
database_cross_reference: PMID:32901987
database_cross_reference: PMID:32920292
database_cross_reference: Reaxys:1939047
database_cross_reference: Wikipedia:Thymoquinone
has exact synonym: 2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione
has_obo_namespace: chebi_ontology
has_related_synonym: 2-isopropyl-5-methyl-1,4-benzoquinone
has_related_synonym: 2-isopropyl-5-methyl-p-benzoquinone
has_related_synonym: 2-methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione
has_related_synonym: 5-isopropyl-2-methyl-2,5-cyclohexadiene-1,4-dione
has_related_synonym: TQ
has_related_synonym: p-cymene-2,5-dione
has_related_synonym: p-mentha-3,6-diene-2,5-dione
has_related_synonym: thymoquinon
id: CHEBI:113532
in subset: 3 STAR

4-amino-3-hydroxybutanoate
type: Class
subclass of: CHEBI_36059
subclass of: CHEBI_71666
subclass of: Restriction
  on property: has functional parent
  some values from: butyrate
subclass of: Restriction
  on property: is conjugate base of
  some values from: gamma-amino-beta-hydroxybutyric acid
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_57630
definition: The conjugate base of gamma-amino-beta-hydroxybutyric acid arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C4H8NO3
inchi: InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)/p-1
inchikey: YQGDEPYYFWUPGO-UHFFFAOYSA-M
mass: 118.11126
monoisotopicmass: 118.05097
smiles: NCC(O)CC([O-])=O
database_cross_reference: CAS:352-21-6
database_cross_reference: KEGG:C03678
has exact synonym: 4-Amino-3-hydroxybutanoate
has_obo_namespace: chebi_ontology
id: CHEBI:11955
in subset: 3 STAR

2-amino-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile
type: Class
subclass of: CHEBI_51683
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 24391744
imported from: chebi.owl
charge: 0
formula: C20H22N2O5
inchi: InChI=1S/C20H22N2O5/c1-10-5-13(23)19-17(6-10)27-20(22)12(9-21)18(19)11-7-15(25-3)16(26-4)8-14(11)24-2/h7-8,10,18H,5-6,22H2,1-4H3
inchikey: SQVQEPYBUYDLRQ-UHFFFAOYSA-N
mass: 370.400
monoisotopicmass: 370.15287
smiles: CC1CC2=C(C(C(=C(O2)N)C#N)C3=CC(=C(C=C3OC)OC)OC)C(=O)C1
database_cross_reference: LINCS:LSM-32699
has_obo_namespace: chebi_ontology
id: CHEBI:121256
in subset: 2 STAR

5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl ester
type: Class
subclass of: piperazines
subclass of: pyridines
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000017273
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 26565666
imported from: chebi.owl
charge: 0
formula: C24H23N5O2
inchi: InChI=1S/C24H23N5O2/c1-2-31-24(30)20-16-19(17-25)23(27-22(20)18-8-4-3-5-9-18)29-14-12-28(13-15-29)21-10-6-7-11-26-21/h3-11,16H,2,12-15H2,1H3
inchikey: JZKXGDVUHZCZAG-UHFFFAOYSA-N
mass: 413.473
monoisotopicmass: 413.18518
smiles: CCOC(=O)C1=C(N=C(C(=C1)C#N)N2CCN(CC2)C3=CC=CC=N3)C4=CC=CC=C4
database_cross_reference: LINCS:LSM-33271
has_obo_namespace: chebi_ontology
id: CHEBI:121828
in subset: 2 STAR

N2-[2-(4-methylphenyl)-5-phenyl-3-pyrazolyl]benzene-1,2-diamine
type: Class
subclass of: pyrazoles
subclass of: CHEBI_36820
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000017273
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 21383145
imported from: chebi.owl
charge: 0
formula: C22H20N4
inchi: InChI=1S/C22H20N4/c1-16-11-13-18(14-12-16)26-22(24-20-10-6-5-9-19(20)23)15-21(25-26)17-7-3-2-4-8-17/h2-15,24H,23H2,1H3
inchikey: PMUPQNIDIMQBFR-UHFFFAOYSA-N
mass: 340.422
monoisotopicmass: 340.16880
database_cross_reference: LINCS:LSM-34585
has_obo_namespace: chebi_ontology
id: CHEBI:123143
in subset: 2 STAR

4-guanidinobenzoic acid
type: Class
subclass of: benzoic acids
subclass of: guanidines
definition: Benzoic acid substituted at the para position by a guanidino group.
imported from: chebi.owl
charge: 0
formula: C8H9N3O2
inchi: InChI=1S/C8H9N3O2/c9-8(10)11-6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)(H4,9,10,11)
inchikey: SXTSBZBQQRIYCU-UHFFFAOYSA-N
mass: 179.17600
monoisotopicmass: 179.06948
smiles: NC(=N)Nc1ccc(cc1)C(O)=O
has_alternative_id: CHEBI:42695
database_cross_reference: Beilstein:2369015
database_cross_reference: CAS:16060-65-4
database_cross_reference: DrugBank:DB02459
database_cross_reference: PDBeChem:GBS
database_cross_reference: PMID:10848923
database_cross_reference: PMID:1144503
database_cross_reference: PMID:28166217
database_cross_reference: Patent:JP2004284982
database_cross_reference: Reaxys:2369015
has exact synonym: 4-carbamimidamidobenzoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: 4-Guanidino-benzoic acid
has_related_synonym: p-guanidinobenzoic acid
id: CHEBI:125204
in subset: 3 STAR

amodiaquine(1+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: amodiaquine
definition: An organic cation obtained by protonation of the tertiary amino group of amodiaquine; major species at pH 7.3.
imported from: chebi.owl
charge: +1
formula: C20H23ClN3O
inchi: InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)/p+1
inchikey: OVCDSSHSILBFBN-UHFFFAOYSA-O
mass: 356.870
monoisotopicmass: 356.15242
database_cross_reference: PMID:26427316
has_obo_namespace: chebi_ontology
has_related_synonym: amodiaquine
has_related_synonym: amodiaquine cation
id: CHEBI:131327
in subset: 3 STAR

N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+)
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_47495
definition: An organic cation obtained by protonation of the isoquinoline and secondary amino functions of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide.
imported from: chebi.owl
charge: +2
formula: C20H22BrN3O2S
inchikey: ZKZXNDJNWUTGDK-UHFFFAOYSA-P
mass: 448.380
monoisotopicmass: 447.06051
smiles: [H]C(C[NH2+]CCNS(=O)(=O)C1=CC=CC2=C1C=C[NH+]=C2)=C([H])C1=CC=C(Br)C=C1
has_obo_namespace: chebi_ontology
id: CHEBI:131489
in subset: 3 STAR

Mycoplasma genitalium metabolite
type: Class
subclass of: CHEBI_76969
definition: Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Mycoplasma genitalium metabolites
id: CHEBI:131604
in subset: 3 STAR

dicarboxylic acid monoester(1-)
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_36244
definition: A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:131605
in subset: 3 STAR

dicarboxylic acids and O-substituted derivatives
type: Class
subclass of: CHEBI_36586
definition: A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acids and derivatives
id: CHEBI:131927
in subset: 3 STAR

1,4-benzoquinones
type: Class
subclass of: benzoquinones
subclass of: p-quinones
definition: Any member of the class of benzoquinones that is 1,4-benzoquinone or its C-substituted derivatives.
imported from: chebi.owl
charge: 0
formula: C6O2R4
mass: 104.063
monoisotopicmass: 103.98983
smiles: O=C1C(*)=C(*)C(=O)C(*)=C1*
has_obo_namespace: chebi_ontology
has_related_synonym: a quinone
has_related_synonym: p-benzoquinones
has_related_synonym: para-benzoquinones
id: CHEBI:132124
in subset: 3 STAR

anilide
type: Class
subclass of: benzenes
subclass of: CHEBI_62733
subclass of: Restriction
  on property: has functional parent
  some values from: aniline
definition: Any aromatic amide obtained by acylation of aniline.
imported from: chebi.owl
charge: 0
formula: C7H6NOR
mass: 120.12860
monoisotopicmass: 120.04494
smiles: [*]C(=O)Nc1ccccc1
database_cross_reference: KEGG:C01402
database_cross_reference: PMID:23535982
database_cross_reference: PMID:23968552
database_cross_reference: PMID:24273122
database_cross_reference: PMID:6205897
has_obo_namespace: chebi_ontology
has_related_synonym: N-phenyl amide
has_related_synonym: N-phenyl amides
has_related_synonym: an anilide
id: CHEBI:13248
in subset: 3 STAR

fangchinoline
type: Class
subclass of: bisbenzylisoquinoline alkaloid
subclass of: aromatic ether
subclass of: CHEBI_51026
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63726
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64947
subclass of: Restriction
  on property: has role
  some values from: CHEBI_67079
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
definition: A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity.
imported from: chebi.owl
charge: 0
formula: C37H40N2O6
inchi: InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1
inchikey: IIQSJHUEZBTSAT-VMPREFPWSA-N
mass: 608.725
monoisotopicmass: 608.28864
database_cross_reference: CAS:436-77-1
database_cross_reference: PMID:18161288
database_cross_reference: PMID:19428795
database_cross_reference: PMID:19764054
database_cross_reference: PMID:20030508
database_cross_reference: PMID:20208355
database_cross_reference: PMID:21418191
database_cross_reference: PMID:22130369
database_cross_reference: PMID:22720080
database_cross_reference: PMID:23112944
database_cross_reference: PMID:23401195
database_cross_reference: PMID:23452799
database_cross_reference: PMID:23596478
database_cross_reference: PMID:24568493
database_cross_reference: PMID:24856768
database_cross_reference: PMID:25539072
database_cross_reference: PMID:25645647
database_cross_reference: PMID:25754692
database_cross_reference: PMID:25872479
database_cross_reference: PMID:26408176
database_cross_reference: PMID:26512898
database_cross_reference: PMID:26893655
database_cross_reference: Reaxys:78975
database_cross_reference: Wikipedia:Fangchinoline
has exact synonym: (1beta)-6,6',12-trimethoxy-2,2'-dimethylberbaman-7-ol
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-fangchinoline
has_related_synonym: (+)-limacine
has_related_synonym: (1beta)-2,2'-dimethyl-6,6',12-trimethoxyberbaman-7-ol
has_related_synonym: 7-O-demethyltetrandrine
id: CHEBI:132893
in subset: 3 STAR

ibuprofen(1-)
type: Class
subclass of: CHEBI_35757
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI 5855
definition: A monocarboxylic acid anion that is the conjugate base of ibuprofen, obtained by deprotonation of the carboxy group; major species at pH 7.3.
imported from: chebi.owl
charge: -1
formula: C13H17O2
inchi: InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/p-1
inchikey: HEFNNWSXXWATRW-UHFFFAOYSA-M
mass: 205.273
monoisotopicmass: 205.12340
smiles: C=1C=C(C=CC1C(C(=O)[O-])C)CC(C)C
database_cross_reference: Reaxys:4784081
has exact synonym: 2-[4-(2-methylpropyl)phenyl]propanoate
has_obo_namespace: chebi_ontology
has_related_synonym: ibuprofen
has_related_synonym: ibuprofen anion
id: CHEBI:132922
in subset: 3 STAR

aspartate
type: Class
subclass of: alpha-amino-acid anion
subclass of: dicarboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: aspartic acid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:132943
in subset: 1 STAR

octadec-9-enoate
type: Class
subclass of: CHEBI_78049
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_36021
definition: An octadecenoate in which the double bond is at C-9.
imported from: chebi.owl
charge: -1
formula: C18H33O2
inchi: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/p-1
inchikey: ZQPPMHVWECSIRJ-UHFFFAOYSA-M
mass: 281.454
monoisotopicmass: 281.24860
smiles: C(=CCCCCCCCC)CCCCCCCC(=O)[O-]
has exact synonym: octadec-9-enoate
has_obo_namespace: chebi_ontology
has_related_synonym: 9-octadecenoate
has_related_synonym: C18:1, n-9(1-)
has_related_synonym: Delta(9)-octadecenoate
id: CHEBI:132944
in subset: 3 STAR

elbasvir
type: Class
subclass of: carbamate ester
subclass of: imidazoles
subclass of: CHEBI_36820
subclass of: CHEBI_38163
subclass of: CHEBI_46766
subclass of: CHEBI_84129
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
subclass of: Restriction
  on property: has role
  some values from: CHEBI_62868
subclass of: Restriction
  on property: has role
  some values from: CHEBI_85185
definition: A complex organic heterotetracyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with grazoprevir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults.
imported from: chebi.owl
charge: 0
formula: C49H55N9O7
inchi: InChI=1S/C49H55N9O7/c1-27(2)41(54-48(61)63-5)45(59)56-20-10-14-37(56)43-50-25-34(52-43)30-17-19-36-32(22-30)23-39-33-18-16-31(24-40(33)65-47(58(36)39)29-12-8-7-9-13-29)35-26-51-44(53-35)38-15-11-21-57(38)46(60)42(28(3)4)55-49(62)64-6/h7-9,12-13,16-19,22-28,37-38,41-42,47H,10-11,14-15,20-21H2,1-6H3,(H,50,52)(H,51,53)(H,54,61)(H,55,62)/t37-,38-,41-,42-,47-/m0/s1
inchikey: BVAZQCUMNICBAQ-PZHYSIFUSA-N
mass: 882.019
monoisotopicmass: 881.42245
database_cross_reference: CAS:1370468-36-2
database_cross_reference: Drug_Central:5080
database_cross_reference: KEGG:D10625
database_cross_reference: PMID:24127258
database_cross_reference: PMID:25467591
database_cross_reference: PMID:26303801
database_cross_reference: PMID:26371152
database_cross_reference: PMID:26456905
database_cross_reference: PMID:26532861
database_cross_reference: PMID:26818134
database_cross_reference: PMID:26849059
database_cross_reference: PMID:26926625
database_cross_reference: PMID:26927874
database_cross_reference: PMID:26933896
database_cross_reference: PMID:26938699
database_cross_reference: PMID:26943930
database_cross_reference: PMID:27091555
database_cross_reference: PMID:27403342
database_cross_reference: PMID:27418810
database_cross_reference: PMID:27440554
database_cross_reference: Reaxys:22434581
database_cross_reference: Wikipedia:Elbasvir
has exact synonym: methyl {(2S)-1-[(2S)-2-{4-[(6S)-3-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}pyrrolidin-2-yl]-1H-imidazol-4-yl}-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazin-10-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate
has_obo_namespace: chebi_ontology
has_related_synonym: MK 8742
has_related_synonym: MK-8742
has_related_synonym: MK8742
has_related_synonym: elbasvir
id: CHEBI:132967
in subset: 3 STAR

radiosensitizing agent
type: Class
subclass of: drug
definition: A drug that makes increases the sensitivity of tumour cells to radiation therapy.
imported from: chebi.owl
database_cross_reference: PMID:12520460
database_cross_reference: Wikipedia:Radiosensitizer
has_obo_namespace: chebi_ontology
has_related_synonym: radiosensitiser
has_related_synonym: radiosensitisers
has_related_synonym: radiosensitising agent
has_related_synonym: radiosensitising agents
has_related_synonym: radiosensitizer
has_related_synonym: radiosensitizers
has_related_synonym: radiosensitizing agents
id: CHEBI:132992
in subset: 3 STAR

bisbenzylisoquinoline alkaloid
type: Class
subclass of: benzylisoquinoline alkaloid
definition: A type of benzylisoquinoline alkaloid whose structures are built up of two benzylisoquinoline units linked by ether bridges. Various structural patterns resulting from additional bridging between the two units by direct carbon-carbon bridging or by methylenedioxy groups are common.
imported from: chebi.owl
database_cross_reference: PMID:1955879
database_cross_reference: PMID:2191354
database_cross_reference: PMID:3323421
has_obo_namespace: chebi_ontology
has_related_synonym: bis(benzylisoquinoline) alkaloid
has_related_synonym: bis(benzylisoquinoline) alkaloids
has_related_synonym: bis-benzylisoquinoline alkaloid
has_related_synonym: bis-benzylisoquinoline alkaloids
has_related_synonym: bisbenzylisoquinoline alkaloids
id: CHEBI:133004
in subset: 3 STAR

L-lysine zwitterion
type: Class
subclass of: CHEBI_59869
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-lysinium(1+)
subclass of: Restriction
  on property: is tautomer of
  some values from: L-lysine
definition: An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-lysine; major species at pH 7.3.
imported from: chebi.owl
charge: 0
formula: C6H14N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1
inchikey: KDXKERNSBIXSRK-YFKPBYRVSA-N
mass: 146.188
monoisotopicmass: 146.10553
smiles: [O-]C([C@H](CCCCN)[NH3+])=O
has exact synonym: (2S)-6-amino-2-azaniumylhexanoate
has_obo_namespace: chebi_ontology
has_related_synonym: L-lysine
has_related_synonym: Lys
has_related_synonym: lysine zwitterion
id: CHEBI:133538
in subset: 3 STAR

N-acylethanolamine 18:1
type: Class
subclass of: CHEBI_85282
definition: An N-acylethanolamine in which the acyl group contains 18 carbons and 1 double bond.
imported from: chebi.owl
charge: 0
formula: C20H37NO2
mass: 323.514
monoisotopicmass: 323.28243
smiles: N(C(*)=O)CCO
has_obo_namespace: chebi_ontology
has_related_synonym: NAE 18:1
id: CHEBI:134158
in subset: 3 STAR

volatile organic compound
type: Class
subclass of: CHEBI_72695
definition: Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa.
imported from: chebi.owl
database_cross_reference: Wikipedia:Volatile_organic_compound
has_obo_namespace: chebi_ontology
has_related_synonym: VOC
has_related_synonym: VOCs
has_related_synonym: volatile organic compounds
id: CHEBI:134179
in subset: 3 STAR

alkanesulfonate oxoanion
type: Class
subclass of: organosulfonate oxoanion
definition: An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups.
imported from: chebi.owl
charge: -1
formula: CH2O3SR
mass: 94.091
monoisotopicmass: 93.97246
smiles: C(S([O-])(=O)=O)*
has_alternative_id: CHEBI:22318
database_cross_reference: MetaCyc:Alkanesulfonates
has_obo_namespace: chebi_ontology
has_related_synonym: alkanesulfonate oxoanions
has_related_synonym: alkanesulfonates
has_related_synonym: an alkanesulfonate
id: CHEBI:134249
in subset: 3 STAR

favipiravir
type: Class
subclass of: primary carboxamide
subclass of: CHEBI_37143
subclass of: CHEBI_71633
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR Q809M3
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
definition: A member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan.
definition source: PMID: 32020029
definition source: https://www.drugbank.ca/drugs/DB12466
imported from: chebi.owl
charge: 0
formula: C5H4FN3O2
inchi: InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
inchikey: ZCGNOVWYSGBHAU-UHFFFAOYSA-N
mass: 157.104
monoisotopicmass: 157.02875
smiles: NC(=O)C1=NC(F)=CN=C1O
database_cross_reference: CAS:259793-96-9
database_cross_reference: Chemspider:431002
database_cross_reference: DrugBank:DB12466
database_cross_reference: Drug_Central:4887
database_cross_reference: KEGG:D09537
database_cross_reference: PMCID:PMC7971419
database_cross_reference: PMID:28105854
database_cross_reference: PMID:28324644
database_cross_reference: PMID:28465146
database_cross_reference: PMID:28769016
database_cross_reference: PMID:29289664
database_cross_reference: PMID:29289666
database_cross_reference: PMID:29369776
database_cross_reference: PMID:29765101
database_cross_reference: PMID:29936152
database_cross_reference: PMID:29982696
database_cross_reference: PMID:30715325
database_cross_reference: PMID:30951731
database_cross_reference: PMID:31195019
database_cross_reference: PMID:31507197
database_cross_reference: PMID:31673977
database_cross_reference: PMID:32174453
database_cross_reference: PMID:32553844
database_cross_reference: PMID:32645335
database_cross_reference: PMID:32834770
database_cross_reference: PMID:32836314
database_cross_reference: PMID:32863356
database_cross_reference: PMID:33108587
database_cross_reference: PMID:33232871
database_cross_reference: PMID:33268271
database_cross_reference: PMID:33418497
database_cross_reference: PMID:33451007
database_cross_reference: PMID:33457366
database_cross_reference: PMID:33478340
database_cross_reference: PMID:33494498
database_cross_reference: PMID:33526596
database_cross_reference: PMID:33649117
database_cross_reference: PMID:33859168
database_cross_reference: Reaxys:9697246
database_cross_reference: Wikipedia:Favipiravir
has exact synonym: 6-fluoro-3-hydroxypyrazine-2-carboxamide
has_obo_namespace: chebi_ontology
has_related_synonym: 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
has_related_synonym: Areplivir
has_related_synonym: Avifavir
has_related_synonym: Avigan
has_related_synonym: Favilavir
has_related_synonym: Favipira
has_related_synonym: T 705
has_related_synonym: T-705
has_related_synonym: T705
has_related_synonym: fapilavir
has_related_synonym: favipiravir
has_related_synonym: favipiravirum
id: CHEBI:134722
in subset: 3 STAR

umifenovir
type: Class
subclass of: CHEBI_46867
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: capable of negatively regulating
  some values from: CIDO_0000187
definition source: PMID: 32373347
imported from: chebi.owl
charge: 0
formula: C22H25BrN2O3S
inchikey: KCFYEAOKVJSACF-UHFFFAOYSA-N
mass: 477.416
monoisotopicmass: 476.07693
database_cross_reference: CAS:131707-25-0
database_cross_reference: Drug_Central:4868
has_obo_namespace: chebi_ontology
has_related_synonym: arbidol
has_related_synonym: arbidole
id: CHEBI:134730
in subset: 2 STAR

chlorphenoxamine
type: Class
subclass of: CHEBI_51614
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C18H22ClNO
inchi: InChI=1S/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3
inchikey: KKHPNPMTPORSQE-UHFFFAOYSA-N
mass: 303.827
monoisotopicmass: 303.13899
database_cross_reference: CAS:77-38-3
database_cross_reference: Drug_Central:617
database_cross_reference: HMDB:HMDB0240223
has_obo_namespace: chebi_ontology
has_related_synonym: chlorphenoxamine hydrochloride
id: CHEBI:135288
in subset: 2 STAR

nafamostat
type: Class
subclass of: benzoic acids
subclass of: guanidines
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P00734
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P00742
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P00748
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P05362
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P06870
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P07477
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: PMID: 28855003; PMID: 30711575; PMID: 27550352
definition source: Reference: PMID: 32470470
definition source: https://www.drugbank.ca/drugs/DB12598
imported from: chebi.owl
charge: 0
formula: C19H17N5O2
inchi: InChI=1S/C19H17N5O2/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23/h1-10H,(H3,20,21)(H4,22,23,24)
inchikey: MQQNFDZXWVTQEH-UHFFFAOYSA-N
mass: 347.371
monoisotopicmass: 347.13822
database_cross_reference: CAS:81525-10-2
database_cross_reference: Drug_Central:1867
has_obo_namespace: chebi_ontology
has_related_synonym: FUT-175
has_related_synonym: nafamostat HCl
has_related_synonym: nafamostat dihydrochloride
has_related_synonym: nafamostat hydrochloride
has_related_synonym: nafamostat mesilate
has_related_synonym: nafamostat mesylate
has_related_synonym: nafamstat
has_related_synonym: ronastat
id: CHEBI:135466
in subset: 2 STAR

camostat
type: Class
subclass of: tertiary carboxamide
subclass of: guanidines
subclass of: carboxylic ester
subclass of: CHEBI_36054
subclass of: CHEBI_51307
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P07477
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: capable of inhibiting activity of
  some values from: PR O15393
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: antihypertensive agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48675
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64926
subclass of: Restriction
  on property: has role
  some values from: CHEBI_67079
subclass of: Restriction
  on property: has role
  some values from: inhibitor
subclass of: Restriction
  on property: has functional parent
  some values from: 4-guanidinobenzoic acid
subclass of: Restriction
  on property: is conjugate base of
  some values from: camostat(1+)
definition: A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
definition source: PMID: 28855003; PMID: 25666761
definition source: PMID: 32142651
definition source: Reference: PMID: 22496216
definition source: https://www.drugbank.ca/drugs/DB13729
imported from: chebi.owl
charge: 0
formula: C20H22N4O5
inchi: InChI=1S/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)
inchikey: XASIMHXSUQUHLV-UHFFFAOYSA-N
mass: 398.419
monoisotopicmass: 398.15902
database_cross_reference: CAS:59721-28-7
database_cross_reference: Chemspider:2440
database_cross_reference: DrugBank:DB13729
database_cross_reference: Drug_Central:471
database_cross_reference: KEGG:D07606
database_cross_reference: PMCID:PMC7809394
database_cross_reference: PMID:23412700
database_cross_reference: PMID:26166259
database_cross_reference: PMID:26887332
database_cross_reference: PMID:33176395
database_cross_reference: PMID:33225308
database_cross_reference: PMID:33505639
database_cross_reference: PMID:33564221
database_cross_reference: PMID:33676899
database_cross_reference: PMID:7341342
database_cross_reference: Wikipedia:Camostat
has exact synonym: 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
has_obo_namespace: chebi_ontology
has_related_synonym: 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
has_related_synonym: N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
has_related_synonym: camostat
has_related_synonym: camostatum
id: CHEBI:135632
in subset: 3 STAR

triparanol
type: Class
subclass of: stilbenoid
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
definition source: PMID: 30893774; PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C27H32ClNO2
inchi: InChI=1S/C27H32ClNO2/c1-4-29(5-2)18-19-31-26-16-12-24(13-17-26)27(30,23-10-6-21(3)7-11-23)20-22-8-14-25(28)15-9-22/h6-17,30H,4-5,18-20H2,1-3H3
inchikey: SYHDSBBKRLVLFF-UHFFFAOYSA-N
mass: 438.002
monoisotopicmass: 437.21216
database_cross_reference: CAS:78-41-1
database_cross_reference: Drug_Central:2761
has_obo_namespace: chebi_ontology
has_related_synonym: clotrox
has_related_synonym: metasclene
has_related_synonym: metasqualene
has_related_synonym: trianel
has_related_synonym: triparin
has_related_synonym: tropalin
id: CHEBI:135714
in subset: 2 STAR

bazedoxifene
type: Class
subclass of: CHEBI_48559
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR Q92731
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P03372
subclass of: Restriction
  on property: chemical has protein target as agonist
  some values from: PR P03372
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
definition source: PMID: 32366720
definition source: https://www.drugbank.ca/drugs/DB06401
imported from: chebi.owl
charge: 0
formula: C30H34N2O3
inchi: InChI=1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
inchikey: UCJGJABZCDBEDK-UHFFFAOYSA-N
mass: 470.604
monoisotopicmass: 470.25694
database_cross_reference: CAS:198481-32-2
database_cross_reference: Drug_Central:4334
has_obo_namespace: chebi_ontology
has_related_synonym: TSE-424
has_related_synonym: TSE424
has_related_synonym: bazedoxifene acetate
has_related_synonym: conbriza
id: CHEBI:135947
in subset: 2 STAR

glycol
type: Class
subclass of: diol
definition: A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
imported from: chebi.owl
has exact synonym: glycols
has_obo_namespace: chebi_ontology
has_related_synonym: Glykol
id: CHEBI:13643
in subset: 3 STAR

aci-nitro compound
type: Class
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has functional parent
  some values from: oxime
subclass of: Restriction
  on property: is tautomer of
  some values from: C-nitro compound
definition: Organonitrogen compounds that have the general structure R(1)(R(2))C=N(O)OH (R(1),R(2) = H, organyl). They are tautomers of C-nitro compounds.
imported from: chebi.owl
charge: 0
formula: CHNO2R2
mass: 59.024
monoisotopicmass: 59.00073
smiles: C(*)(=[N+](O)[O-])*
has_obo_namespace: chebi_ontology
has_related_synonym: aci-nitro compounds
has_related_synonym: oxime N-oxide
has_related_synonym: oxime N-oxides
id: CHEBI:136622
in subset: 3 STAR

3-oxo-Delta(4)-steroid group
type: Class
subclass of: organic group
definition: An organic group derived from any 3-oxo-Delta(4)-steroid.
imported from: chebi.owl
charge: 0
formula: C6H6O
mass: 94.111
monoisotopicmass: 94.04186
smiles: C1=C(C*)*C(CC1=O)*
has_obo_namespace: chebi_ontology
has_related_synonym: a 3-oxo-Delta4-steroid group
id: CHEBI:136849
in subset: 3 STAR

pro-agent
type: Class
subclass of: application
definition: A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent.
imported from: chebi.owl
database_cross_reference: PMID:26449612
has_obo_namespace: chebi_ontology
has_related_synonym: pro-agents
has_related_synonym: proagent
has_related_synonym: proagents
id: CHEBI:136859
in subset: 3 STAR

5beta steroid
type: Class
subclass of: steroid
definition: Any steroid that has beta-configuration at position 5.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: 5beta steroids
has_related_synonym: 5beta-steroid
has_related_synonym: 5beta-steroids
id: CHEBI:136889
in subset: 3 STAR

JQ1
type: Class
subclass of: tert-butyl ester
subclass of: carboxylic ester
subclass of: CHEBI_36683
subclass of: CHEBI_84232
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: bromodomain-containing protein 4 inhibitor
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48422
subclass of: Restriction
  on property: has role
  some values from: CHEBI_67079
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77307
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties.
definition source: Reference: PMID: 24391744
imported from: chebi.owl
charge: 0
formula: C23H25ClN4O2S
inchikey: DNVXATUJJDPFDM-KRWDZBQOSA-N
mass: 456.990
monoisotopicmass: 456.13867
has_alternative_id: CHEBI:95080
database_cross_reference: CAS:1268524-70-4
database_cross_reference: LINCS:LSM-6332
database_cross_reference: PDBeChem:JQ1
database_cross_reference: PMID:20871596
database_cross_reference: PMID:23911322
database_cross_reference: PMID:26206333
database_cross_reference: PMID:26733615
database_cross_reference: PMID:26791045
database_cross_reference: PMID:26830473
database_cross_reference: PMID:26908627
database_cross_reference: PMID:27117003
database_cross_reference: PMID:27292261
database_cross_reference: PMID:27440272
database_cross_reference: PMID:27443262
database_cross_reference: PMID:27528027
database_cross_reference: PMID:27531767
database_cross_reference: PMID:27539364
database_cross_reference: PMID:27572308
database_cross_reference: PMID:27573714
database_cross_reference: PMID:27758824
database_cross_reference: PMID:27764802
database_cross_reference: PMID:27864418
database_cross_reference: PMID:28026145
database_cross_reference: PMID:28059436
database_cross_reference: PMID:28063381
database_cross_reference: PMID:28100400
database_cross_reference: PMID:28103888
database_cross_reference: PMID:28105454
database_cross_reference: PMID:28107481
database_cross_reference: PMID:28118076
database_cross_reference: PMID:28134933
database_cross_reference: PMID:28143717
database_cross_reference: PMID:28248992
database_cross_reference: PMID:28254412
database_cross_reference: PMID:28270499
database_cross_reference: PMID:28275007
database_cross_reference: PMID:28322577
database_cross_reference: PMID:28356707
database_cross_reference: PMID:28368473
database_cross_reference: PMID:28418907
database_cross_reference: PMID:28467486
database_cross_reference: PMID:28484091
database_cross_reference: PMID:28490802
database_cross_reference: PMID:28504695
database_cross_reference: PMID:28515341
database_cross_reference: Reaxys:21994154
database_cross_reference: Wikipedia:JQ1
has exact synonym: JQ1
has exact synonym: tert-butyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-JQ1
has_related_synonym: (S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate
has_related_synonym: (S)-JQ1
has_related_synonym: JQ1 Compound
has_related_synonym: TEN-010
id: CHEBI:137113
in subset: 3 STAR

bromodomain-containing protein 4 inhibitor
type: Class
subclass of: inhibitor
subclass of: CHEBI_52206
definition: Any inhibitor of bromodomain-containing protein 4 (BRD4).
imported from: chebi.owl
database_cross_reference: Wikipedia:BRD4
has_obo_namespace: chebi_ontology
has_related_synonym: BRD4 inhibitor
has_related_synonym: BRD4 inhibitors
has_related_synonym: bromodomain-containing protein 4 inhibitors
id: CHEBI:137114
in subset: 3 STAR

alkylamine
type: Class
subclass of: primary amine
subclass of: Restriction
  on property: is conjugate base of
  some values from: alkylaminium
definition: Any primary amine in which the substituent attached to nitrogen is an alkyl group.
imported from: chebi.owl
charge: 0
formula: H2NR
mass: 16.023
monoisotopicmass: 16.01872
smiles: N[*]
has_alternative_id: CHEBI:2587
database_cross_reference: KEGG:C01664
has exact synonym: Alkylamine
has_obo_namespace: chebi_ontology
id: CHEBI:13759
in subset: 3 STAR

tertiary ammonium ion
type: Class
subclass of: organic cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_50996
definition: An organic cation obtained by protonation of the amino group of any tertiary amino compound.
imported from: chebi.owl
charge: +1
formula: HNR3
mass: 15.015
monoisotopicmass: 15.01090
smiles: [NH+](*)(*)*
has_obo_namespace: chebi_ontology
has_related_synonym: a tertiary amine
has_related_synonym: tertiary amine(1+)
has_related_synonym: tertiary ammonium ions
id: CHEBI:137982
in subset: 3 STAR

endocrine disruptor
type: Class
subclass of: CHEBI_51061
definition: Any compound that can disrupt the functions of the endocrine (hormone) system
imported from: chebi.owl
database_cross_reference: PMID:27929035
database_cross_reference: PMID:28356401
database_cross_reference: PMID:28526231
database_cross_reference: Wikipedia:Endocrine_disruptor
has_obo_namespace: chebi_ontology
has_related_synonym: endocrine disrupting chemical
has_related_synonym: endocrine disrupting chemicals
has_related_synonym: endocrine disrupting compound
has_related_synonym: endocrine disrupting compounds
has_related_synonym: endocrine disruptors
has_related_synonym: endocrine-disrupting chemical
has_related_synonym: endocrine-disrupting chemicals
has_related_synonym: hormonally active agent
has_related_synonym: hormonally active agents
id: CHEBI:138015
in subset: 3 STAR

ATPase motor cytoplasmic dynein inhibitor
type: Class
subclass of: inhibitor
subclass of: CHEBI_52206
definition: Any inhibitor of ATPase motor cytoplasmic dynein.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ATPase motor cytoplasmic dynein inhibitors
id: CHEBI:138090
in subset: 3 STAR

inorganic acid
type: Class
subclass of: CHEBI_39141
definition: A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
imported from: chebi.owl
database_cross_reference: Wikipedia:Mineral_acid
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic acids
has_related_synonym: mineral acid
has_related_synonym: mineral acids
id: CHEBI:138103
in subset: 3 STAR

gas molecular entity
type: Class
subclass of: main group molecular entity
definition: Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
imported from: chebi.owl
database_cross_reference: Wikipedia:https://en.wikipedia.org/wiki/Gas
has_obo_namespace: chebi_ontology
has_related_synonym: gas molecular entities
has_related_synonym: gaseous molecular entities
has_related_synonym: gaseous molecular entity
id: CHEBI:138675
in subset: 3 STAR

autophagy inducer
type: Class
subclass of: CHEBI_52206
definition: Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: autophagocytosis inducer
has_related_synonym: autophagocytosis inducers
has_related_synonym: autophagy inducers
id: CHEBI:138880
in subset: 3 STAR

carbamate
type: Class
subclass of: CHEBI_37022
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbamic acid
imported from: chebi.owl
charge: -1
formula: CH2NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-M
mass: 60.03212
monoisotopicmass: 60.00910
smiles: NC([O-])=O
database_cross_reference: Beilstein:3903503
database_cross_reference: CAS:302-11-4
database_cross_reference: Gmelin:239604
has exact synonym: carbamate
has_obo_namespace: chebi_ontology
has_related_synonym: Carbamat
has_related_synonym: Karbamat
has_related_synonym: carbamate ion
has_related_synonym: carbamic acid, ion(1-)
id: CHEBI:13941
in subset: 3 STAR

EC 4.1.1.17 (ornithine decarboxylase) inhibitor
type: Class
subclass of: CHEBI_76906
definition: An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17).
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: EC 4.1.1.17 (ornithine decarboxylase) inhibitors
has_related_synonym: EC 4.1.1.17 inhibitor
has_related_synonym: EC 4.1.1.17 inhibitors
has_related_synonym: L-ornithine carboxy-lyase (putrescine-forming) inhibitor
has_related_synonym: L-ornithine carboxy-lyase (putrescine-forming) inhibitors
has_related_synonym: L-ornithine carboxy-lyase inhibitor
has_related_synonym: L-ornithine carboxy-lyase inhibitors
has_related_synonym: ODC inhibitor
has_related_synonym: ODC inhibitors
has_related_synonym: SpeC inhibitor
has_related_synonym: SpeC inhibitors
id: CHEBI:139556
in subset: 3 STAR

alpha-hydroxy ketone
type: Class
subclass of: alcohol
subclass of: CHEBI_52396
definition: An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety.
imported from: chebi.owl
database_cross_reference: PMID:15326516
database_cross_reference: PMID:19908854
database_cross_reference: PMID:20382022
database_cross_reference: PMID:23295224
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-hydroxy ketones
has_related_synonym: alpha-hydroxy-ketone
has_related_synonym: alpha-hydroxy-ketones
has_related_synonym: alpha-hydroxyketone
has_related_synonym: alpha-hydroxyketones
id: CHEBI:139588
in subset: 3 STAR

primary alpha-hydroxy ketone
type: Class
subclass of: alpha-hydroxy ketone
subclass of: primary alcohol
definition: An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group.
imported from: chebi.owl
charge: 0
formula: C2H3O2R
mass: 59.044
monoisotopicmass: 59.01330
smiles: *C(C(O)([H])[H])=O
has_obo_namespace: chebi_ontology
has_related_synonym: primary alpha-hydroxy ketones
has_related_synonym: primary alpha-hydroxy-ketone
has_related_synonym: primary alpha-hydroxy-ketones
has_related_synonym: primary alpha-hydroxyketone
has_related_synonym: primary alpha-hydroxyketones
id: CHEBI:139590
in subset: 3 STAR

tertiary alpha-hydroxy ketone
type: Class
subclass of: alpha-hydroxy ketone
subclass of: tertiary alcohol
definition: An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups.
imported from: chebi.owl
charge: 0
formula: C2HO2R3
mass: 57.028
monoisotopicmass: 56.99765
smiles: C(C(=O)*)(O)(*)*
has_obo_namespace: chebi_ontology
has_related_synonym: tertiary alpha-hydroxy ketones
has_related_synonym: tertiary alpha-hydroxy-ketone
has_related_synonym: tertiary alpha-hydroxy-ketones
has_related_synonym: tertiary alpha-hydroxyketone
has_related_synonym: tertiary alpha-hydroxyketones
id: CHEBI:139592
in subset: 3 STAR

primary carboxamide
type: Class
subclass of: CHEBI_37622
definition: A carboxamide resulting from the formal condensation of a carboxylic acid with ammonia; formula RC(=O)NH2.
imported from: chebi.owl
charge: 0
formula: CH2NOR
mass: 44.033
monoisotopicmass: 44.01364
smiles: N(C(*)=O)([H])[H]
has_obo_namespace: chebi_ontology
has_related_synonym: primary carboxamides
id: CHEBI:140324
in subset: 3 STAR

secondary carboxamide
type: Class
subclass of: CHEBI_37622
definition: A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).
imported from: chebi.owl
charge: 0
formula: CHNOR2
mass: 43.025
monoisotopicmass: 43.00581
smiles: N(C(*)=O)(*)[H]
has_obo_namespace: chebi_ontology
has_related_synonym: secondary carboxamides
id: CHEBI:140325
in subset: 3 STAR

tertiary carboxamide
type: Class
subclass of: CHEBI_37622
definition: A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2).
imported from: chebi.owl
charge: 0
formula: CNOR3
mass: 42.017
monoisotopicmass: 41.99799
smiles: N(C(*)=O)(*)*
has_obo_namespace: chebi_ontology
has_related_synonym: tertiary carboxamides
id: CHEBI:140326
in subset: 3 STAR

(2S)-flavan-4-one
type: Class
subclass of: flavanones
definition: Any flavanone in which the chiral centre at position 2 has S-configuration.
imported from: chebi.owl
charge: 0
formula: C15H3O2R9
mass: 215.184
monoisotopicmass: 215.01330
database_cross_reference: MetaCyc:2S-Flavanones
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-flavan-4-ones
has_related_synonym: (2S)-flavanone
has_related_synonym: (2S)-flavanones
has_related_synonym: a (2S)-flavan-4-one
id: CHEBI:140377
in subset: 3 STAR

tert-butyl ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_45895
definition: A carboxylic ester resulting from the formal condensation of a carboxylic acid with tert-butanol.
imported from: chebi.owl
charge: 0
formula: C5H9O2R
mass: 101.124
monoisotopicmass: 101.06025
smiles: C(OC(C)(C)C)(*)=O
has_obo_namespace: chebi_ontology
has_related_synonym: 1,1-dimethylethyl ester
has_related_synonym: 1,1-dimethylethyl esters
has_related_synonym: t-butyl ester
has_related_synonym: t-butyl esters
has_related_synonym: tert-butyl esters
id: CHEBI:140402
in subset: 3 STAR

onalespib
type: Class
subclass of: tertiary carboxamide
subclass of: benzamides
subclass of: isoindoles
subclass of: resorcinols
subclass of: CHEBI_46845
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000008801
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63962
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor.
definition source: Reference: PMID: 33330614
imported from: chebi.owl
charge: 0
formula: C24H31N3O3
inchi: InChI=1S/C24H31N3O3/c1-16(2)20-11-21(23(29)12-22(20)28)24(30)27-14-18-5-4-17(10-19(18)15-27)13-26-8-6-25(3)7-9-26/h4-5,10-12,16,28-29H,6-9,13-15H2,1-3H3
inchikey: IFRGXKKQHBVPCQ-UHFFFAOYSA-N
mass: 409.522
monoisotopicmass: 409.23654
database_cross_reference: CAS:912999-49-6
database_cross_reference: DrugBank:DB06306
database_cross_reference: KEGG:D10719
database_cross_reference: PDBeChem:XJX
database_cross_reference: PMCID:PMC4638428
database_cross_reference: PMID:20662534
database_cross_reference: PMID:21538821
database_cross_reference: PMID:22181674
database_cross_reference: PMID:22714264
database_cross_reference: PMID:23186098
database_cross_reference: PMID:24156782
database_cross_reference: PMID:25336693
database_cross_reference: PMID:25349308
database_cross_reference: PMID:26082332
database_cross_reference: PMID:26248657
database_cross_reference: PMID:26452257
database_cross_reference: PMID:26627081
database_cross_reference: PMID:27156227
database_cross_reference: PMID:27197266
database_cross_reference: PMID:27321499
database_cross_reference: PMID:27673365
database_cross_reference: PMID:28679777
database_cross_reference: PMID:31638190
database_cross_reference: Reaxys:18536397
has exact synonym: (2,4-dihydroxy-5-isopropylphenyl){5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydro-2H-isoindol-2-yl}methanone
has_obo_namespace: chebi_ontology
has_related_synonym: (2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone
has_related_synonym: AT 13387
has_related_synonym: AT-13387
has_related_synonym: AT13387
has_related_synonym: onalespib
has_related_synonym: onalespibum
id: CHEBI:140592
in subset: 3 STAR

fatty acid 4:0
type: Class
subclass of: short-chain fatty acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_78115
definition: Any saturated fatty acid containing 4 carbons.
imported from: chebi.owl
charge: 0
formula: CHO2R
mass: 45.017
monoisotopicmass: 44.99765
smiles: *C(O)=O
has_obo_namespace: chebi_ontology
id: CHEBI:140601
in subset: 3 STAR

L-tyrosinal(1+)
type: Class
subclass of: CHEBI_65296
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_46209
definition: A primary ammonium ion resulting from the protonation of the amino group of L-tyrosinal.
imported from: chebi.owl
charge: +1
formula: C9H12NO2
inchi: InChI=1S/C9H11NO2/c10-8(6-11)5-7-1-3-9(12)4-2-7/h1-4,6,8,12H,5,10H2/p+1/t8-/m0/s1
inchikey: DXGAIOIQACHYRK-QMMMGPOBSA-O
mass: 166.197
monoisotopicmass: 166.08626
smiles: O=C[C@@H]([NH3+])CC=1C=CC(=CC1)O
database_cross_reference: MetaCyc:CPD-21526
database_cross_reference: PMID:23281040
has exact synonym: (2S)-1-(4-hydroxyphenyl)-3-oxopropan-2-aminium
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-1-(p-hydroxyphenyl)-3-oxopropan-2-aminium
has_related_synonym: L-tyrosinal
id: CHEBI:141668
in subset: 3 STAR

hexahydronaphthalenes
type: Class
subclass of: CHEBI_36785
definition: Any carbobycyclic compound that is an hexahydronaphthalene or a compound obtained from an hexahydronaphthalene by formal substitution of one or more hydrogens.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:142348
in subset: 3 STAR

oxime anion
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: oxime
definition: A organic ion resulting from the deprotonation of the hydroxy group of any oxime.
imported from: chebi.owl
charge: -1
formula: CNO
mass: 42.017
monoisotopicmass: 41.99799
smiles: C(*)(=N[O-])*
has exact synonym: oxime anion
has_obo_namespace: chebi_ontology
has_related_synonym: oximate
has_related_synonym: oximates
has_related_synonym: oxime anions
id: CHEBI:142513
in subset: 3 STAR

ML240
type: Class
subclass of: benzimidazoles
subclass of: aromatic amine
subclass of: aromatic ether
subclass of: CHEBI_38530
subclass of: CHEBI_50994
subclass of: CHEBI_50995
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000017273
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A member of the class of quinazolines that is quinazoline which is substituted at positions 2, 5 and 8 by 2-amino-1H-benzimidazol-1-yl, benzylnitrilo and methoxy groups, respectively. It is a ATP-competetive inhibitor of AAA ATPase p97, also known as valosin-containing protein (VCP).
definition source: Reference: PMID: 23316025
imported from: chebi.owl
charge: 0
formula: C23H20N6O
inchi: InChI=1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
inchikey: NHAMBLRUUJAFOY-UHFFFAOYSA-N
mass: 396.445
monoisotopicmass: 396.16986
database_cross_reference: CAS:1346527-98-7
database_cross_reference: PMID:23316025
database_cross_reference: PMID:24878061
database_cross_reference: PMID:25377500
has exact synonym: 2-(2-amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine
has exact synonym: ML240
has_obo_namespace: chebi_ontology
has_related_synonym: 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine
has_related_synonym: 2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine
has_related_synonym: ML 240
has_related_synonym: ML-240
id: CHEBI:143014
in subset: 3 STAR

D-leucine zwitterion
type: Class
subclass of: CHEBI_59871
subclass of: Restriction
  on property: is tautomer of
  some values from: D-leucine
definition: A D-alpha-amino acid zwitterion arising from the transfer of a proton from the carboxy to the amino group of D-leucine; major species at pH 7.3.
imported from: chebi.owl
charge: 0
formula: C6H13NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1
inchikey: ROHFNLRQFUQHCH-RXMQYKEDSA-N
mass: 131.173
monoisotopicmass: 131.09463
smiles: [O-]C([C@@H](CC(C)C)[NH3+])=O
database_cross_reference: MetaCyc:CPD-12150
database_cross_reference: PMID:24419381
has exact synonym: (2R)-2-azaniumyl-4-methylpentanoate
has_obo_namespace: chebi_ontology
has_related_synonym: D-leu
has_related_synonym: D-leucine
id: CHEBI:143079
in subset: 3 STAR

glutamate(1-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glutamate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: glutamic acid
definition: An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group
imported from: chebi.owl
charge: -1
formula: C5H8NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1
inchikey: WHUUTDBJXJRKMK-UHFFFAOYSA-M
mass: 146.12136
monoisotopicmass: 146.04588
smiles: [NH3+]C(CCC([O-])=O)C([O-])=O
database_cross_reference: Gmelin:327908
has exact synonym: glutamate(1-)
has exact synonym: hydrogen glutamate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-ammoniopentanedioate
has_related_synonym: glutamate
has_related_synonym: glutamic acid monoanion
id: CHEBI:14321
in subset: 3 STAR

C-terminal amino acid residue(1-)
type: Class
subclass of: alpha-amino-acid residue anion
imported from: chebi.owl
charge: -1
formula: C2H2NO2R
mass: 72.043
monoisotopicmass: 72.00855
smiles: [O-]C(C(N*)*)=O
has_obo_namespace: chebi_ontology
has_related_synonym: C-terminal amino acid residue
has_related_synonym: amino acid carboxylate group(1-)
id: CHEBI:143819
in subset: 2 STAR

gilteritinib
type: Class
subclass of: primary carboxamide
subclass of: monomethoxybenzene
subclass of: piperidines
subclass of: aromatic amine
subclass of: CHEBI_38314
subclass of: CHEBI_46920
subclass of: CHEBI_46942
subclass of: CHEBI_50995
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P30530
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P36888
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q9UM73
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_62434
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
definition: A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation.
definition source: PMID: 32366720
definition source: https://www.drugbank.ca/drugs/DB12141
imported from: chebi.owl
charge: 0
formula: C29H44N8O3
inchi: InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34)
inchikey: GYQYAJJFPNQOOW-UHFFFAOYSA-N
mass: 552.724
monoisotopicmass: 552.35364
database_cross_reference: CAS:1254053-43-4
database_cross_reference: DrugBank:DB12141
database_cross_reference: KEGG:D10709
database_cross_reference: PMCID:PMC6817455
database_cross_reference: PMID:26279055
database_cross_reference: PMID:27908881
database_cross_reference: PMID:28516360
database_cross_reference: PMID:28645776
database_cross_reference: PMID:29498296
database_cross_reference: PMID:30039554
database_cross_reference: PMID:30514344
database_cross_reference: PMID:30721452
database_cross_reference: PMID:30936061
database_cross_reference: PMID:31069015
database_cross_reference: PMID:31122910
database_cross_reference: PMID:31203997
database_cross_reference: PMID:31320594
database_cross_reference: PMID:31454267
database_cross_reference: PMID:31469903
database_cross_reference: PMID:31528345
database_cross_reference: PMID:31665578
database_cross_reference: PMID:31692922
database_cross_reference: Wikipedia:Gilteritinib
has exact synonym: 6-ethyl-3-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide
has_obo_namespace: chebi_ontology
has_related_synonym: 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)-2-pyrazinecarboxamide
has_related_synonym: 6-ethyl-3-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-[(oxan-4-yl)amino]pyrazine-2-carboxamide
has_related_synonym: ASP 2215
has_related_synonym: ASP-2215
has_related_synonym: ASP2215
has_related_synonym: Xospata
has_related_synonym: gilteritinib
has_related_synonym: gilteritinibum
id: CHEBI:145372
in subset: 3 STAR

donepezil (1+)
type: Class
subclass of: CHEBI_48633
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_53289
definition: A piperidinium ion resulting from the protonation of amino group of donepezil.
imported from: chebi.owl
charge: +1
formula: C24H30NO3
inchi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/p+1
inchikey: ADEBPBSSDYVVLD-UHFFFAOYSA-O
mass: 380.507
monoisotopicmass: 380.22202
smiles: C1(=C(C=C2C(=C1)CC(C2=O)(CC3CC[NH+](CC3)CC4=CC=CC=C4)[H])OC)OC
has exact synonym: 1-benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium
has_obo_namespace: chebi_ontology
id: CHEBI:145498
in subset: 3 STAR

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
type: Class
subclass of: indanones
subclass of: piperidines
subclass of: aromatic ether
definition: A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
imported from: chebi.owl
charge: 0
formula: C24H29NO3
inchi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
inchikey: ADEBPBSSDYVVLD-UHFFFAOYSA-N
mass: 379.500
monoisotopicmass: 379.21474
has exact synonym: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
has_obo_namespace: chebi_ontology
id: CHEBI:145499
in subset: 3 STAR

(R)-donepezil(1+)
type: Class
subclass of: CHEBI_48633
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_53292
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-donepezil(1+)
definition: A piperidinium ion resulting from the protonation of the amino group of (R)-donepezil.
imported from: chebi.owl
charge: +1
formula: C24H30NO3
inchi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/p+1/t20-/m1/s1
inchikey: ADEBPBSSDYVVLD-HXUWFJFHSA-O
mass: 380.507
monoisotopicmass: 380.22202
smiles: C1(=C(C=C2C(=C1)C[C@](C2=O)(CC3CC[NH+](CC3)CC4=CC=CC=C4)[H])OC)OC
has exact synonym: (2R)-1-benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium
has_obo_namespace: chebi_ontology
id: CHEBI:145502
in subset: 3 STAR

(S)-donepezil(1+)
type: Class
subclass of: CHEBI_48633
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_53290
subclass of: Restriction
  on property: is enantiomer of
  some values from: (R)-donepezil(1+)
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:145503
in subset: 1 STAR

macrolide lactam
type: Class
subclass of: lactam
subclass of: macrolide
definition: A macrolide in which the macrocyclic lactone ring includes an amide group.
imported from: chebi.owl
database_cross_reference: PMID:11678663
database_cross_reference: PMID:12227772
database_cross_reference: PMID:15248618
database_cross_reference: PMID:17378533
database_cross_reference: PMID:31226284
has_obo_namespace: chebi_ontology
has_related_synonym: macrolide lactams
id: CHEBI:145565
in subset: 3 STAR

digoxin(1-)
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI 4551
definition: An organic anion that is the conjugate base of digoxin resulting from the deprotonation of furanone moiety; major species at pH 7.3.
imported from: chebi.owl
charge: -1
formula: C41H63O14
inchi: InChI=1S/C41H63O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,18-21,23-31,33-38,42-45,47-48H,6-11,13-17H2,1-5H3/q-1/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
inchikey: MOAVUYWYFFCBNM-PUGKRICDSA-N
mass: 779.942
monoisotopicmass: 779.42233
database_cross_reference: PMID:31994361
database_cross_reference: PMID:32272101
database_cross_reference: PMID:32464466
database_cross_reference: PMID:32488807
database_cross_reference: PMID:32546555
database_cross_reference: PMID:32603789
has exact synonym: 12beta,14-dihydroxy-17beta-(5-oxo-2,5-dihydrofuran-2-id-3-yl)-5beta,14beta-androstan-3beta-yl 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranoside
has_obo_namespace: chebi_ontology
has_related_synonym: digoxin
has_related_synonym: digoxin anion
id: CHEBI:145795
in subset: 3 STAR

digitoxin(1-)
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: digitoxin
definition: An organic anion that is the conjugate base of digitoxin resulting from the deprotonation of furanone moiety; major species at pH 7.3.
imported from: chebi.owl
charge: -1
formula: C41H63O13
inchi: InChI=1S/C41H63O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,19-22,24-31,33-38,42-44,46-47H,6-13,15-18H2,1-5H3/q-1/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
inchikey: YQICPRLGRXWDHI-XUDUSOBPSA-N
mass: 763.943
monoisotopicmass: 763.42742
has_obo_namespace: chebi_ontology
has_related_synonym: digitoxin
has_related_synonym: digitoxin anion
id: CHEBI:145796
in subset: 3 STAR

ouabain(1-)
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_472805
definition: An organic anion that is the conjugate base of ouabain resulting from the deprotonation of the furanone moiety; major species at pH 7.3.
imported from: chebi.owl
charge: -1
formula: C29H43O12
inchi: InChI=1S/C29H43O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,11,13,15-19,21-25,30-32,34-38H,3-6,8-10,12H2,1-2H3/q-1/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1
inchikey: MPLJNVZJPLASQC-HBYQJFLCSA-N
mass: 583.652
monoisotopicmass: 583.27600
database_cross_reference: PMID:31075189
database_cross_reference: PMID:31087249
database_cross_reference: PMID:31170971
database_cross_reference: PMID:32326025
database_cross_reference: PMID:32368275
database_cross_reference: PMID:32488807
database_cross_reference: PMID:32651756
has exact synonym: 1beta,5,11alpha,14,19-pentahydroxy-17beta-(5-oxo-2,5-dihydrofuran-2-id-3-yl)-5beta,14beta-androstan-3beta-yl 6-deoxy-alpha-L-mannopyranoside
has_obo_namespace: chebi_ontology
has_related_synonym: ouabain
has_related_synonym: ouabain anion
id: CHEBI:145798
in subset: 3 STAR

(S)-2-methylbutanoate
type: Class
subclass of: CHEBI_58951
subclass of: CHEBI_58956
subclass of: CHEBI_83976
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_38655
definition: A branched-chain saturated fatty acid anion resulting from the deprotonation of the carboxy group of (S)-2-methylbutanoic acid. The major species at pH 7.3.
imported from: chebi.owl
charge: -1
formula: C5H9O2
inchi: InChI=1S/C5H10O2/c1-3-4(2)5(6)7/h4H,3H2,1-2H3,(H,6,7)/p-1/t4-/m0/s1
inchikey: WLAMNBDJUVNPJU-BYPYZUCNSA-M
mass: 101.126
monoisotopicmass: 101.06080
smiles: [O-]C([C@H](CC)C)=O
database_cross_reference: PMID:16819884
has exact synonym: (2S)-2-methylbutanoate
has exact synonym: (S)-2-methylbutanoate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-methylbutyrate
has_related_synonym: (2S)-2-methylbutyric acid anion
has_related_synonym: (S)-2-methylbutyrate
has_related_synonym: (S)-alpha-methylbutyrate
id: CHEBI:145932
in subset: 3 STAR

antiatherosclerotic agent
type: Class
subclass of: cardiovascular drug
definition: A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
imported from: chebi.owl
has exact synonym: antiatherosclerotic agent
has_obo_namespace: chebi_ontology
has_related_synonym: anti-atherosclerotic agent
has_related_synonym: anti-atherosclerotic agents
has_related_synonym: anti-atherosclerotic drug
has_related_synonym: anti-atherosclerotic drugs
has_related_synonym: antiatherosclerotic agents
has_related_synonym: antiatherosclerotic drug
has_related_synonym: antiatherosclerotic drugs
id: CHEBI:145947
in subset: 3 STAR

remdesivir
type: Class
subclass of: nitrile
subclass of: phosphoramidate ester
subclass of: carboxylic ester
subclass of: aromatic amine
subclass of: CHEBI_37086
subclass of: CHEBI_88341
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P0C6X7
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q05318
subclass of: Restriction
  on property: chemical inhibits in vivo replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vivo replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50266
subclass of: Restriction
  on property: has role
  some values from: CIDO_0000073
subclass of: Restriction
  on property: has functional parent
  some values from: GS-441524
definition: A carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults.
definition source: PMID: 30849247; PMID: 32251768; PMID: 21297106
definition source: PMID: 30849247; PMID: 32251768; PMID: 21297106; PMID: 28659436; PMID: 32054787
definition source: https://en.wikipedia.org/wiki/Remdesivir
definition source: https://pubchem.ncbi.nlm.nih.gov/compound/121304016
definition source: https://www.drugbank.ca/drugs/DB14761
imported from: chebi.owl
charge: 0
formula: C27H35N6O8P
inchi: InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1
inchikey: RWWYLEGWBNMMLJ-YSOARWBDSA-N
mass: 602.585
monoisotopicmass: 602.22540
database_cross_reference: CAS:1809249-37-3
database_cross_reference: DrugBank:DB14761
database_cross_reference: KEGG:D11472
database_cross_reference: PMCID:PMC5630887
database_cross_reference: PMID:26934220
database_cross_reference: PMID:28124907
database_cross_reference: PMID:28262699
database_cross_reference: PMID:28659436
database_cross_reference: PMID:29511076
database_cross_reference: PMID:30275474
database_cross_reference: PMID:30987343
database_cross_reference: PMID:31142680
database_cross_reference: PMID:31233808
database_cross_reference: PMID:31924756
database_cross_reference: PMID:32020029
database_cross_reference: PMID:32054787
database_cross_reference: PMID:32094225
database_cross_reference: PMID:32145386
database_cross_reference: PMID:32147516
database_cross_reference: PMID:32152082
database_cross_reference: PubChem CID: 121304016
database_cross_reference: Wikipedia:Remdesivir
has exact synonym: 2-ethylbutyl N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alaninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-{(2R,3S,4R,5R)-[5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]phenoxy-(S)-phosphorylamino}propionic acid 2-ethyl-butyl ester
has_related_synonym: 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate
has_related_synonym: GS 5734
has_related_synonym: GS-5734
has_related_synonym: GS5734
has_related_synonym: remdesivir
has_related_synonym: remdesivirum
id: CHEBI:145994
in subset: 3 STAR

cinanserin
type: Class
subclass of: secondary carboxamide
subclass of: cinnamamides
subclass of: aryl sulfide
subclass of: CHEBI_50996
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: is conjugate base of
  some values from: cinanserin(1+)
definition: An aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication.
definition source: PMID: 16837072
imported from: chebi.owl
charge: 0
formula: C20H24N2OS
inchi: InChI=1S/C20H24N2OS/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23)/b14-13+
inchikey: RSUVYMGADVXGOU-BUHFOSPRSA-N
mass: 340.490
monoisotopicmass: 340.16093
smiles: C=1(C=CC=CC1NC(=O)/C=C/C=2C=CC=CC2)SCCCN(C)C
database_cross_reference: CAS:1166-34-3
database_cross_reference: PMID:1178659
database_cross_reference: PMID:1301238
database_cross_reference: PMID:142996
database_cross_reference: PMID:15890949
database_cross_reference: PMID:18827378
database_cross_reference: PMID:23131569
database_cross_reference: PMID:23523219
database_cross_reference: PMID:24971515
database_cross_reference: PMID:26851778
database_cross_reference: PMID:30417783
database_cross_reference: PMID:3237811
database_cross_reference: PMID:4254977
database_cross_reference: PMID:4725521
database_cross_reference: PMID:4776363
database_cross_reference: PMID:4929084
database_cross_reference: PMID:4939050
database_cross_reference: PMID:4946100
database_cross_reference: PMID:5348442
database_cross_reference: PMID:5409554
database_cross_reference: PMID:7667390
database_cross_reference: Wikipedia:Cinanserin
has exact synonym: (2E)-N-(2-{[3-(dimethylamino)propyl]sulfanyl}phenyl)-3-phenylprop-2-enamide
has_obo_namespace: chebi_ontology
has_related_synonym: cinanserin
has_related_synonym: cinanserina
has_related_synonym: cinanserine
has_related_synonym: cinanserinum
id: CHEBI:145999
in subset: 3 STAR

emetine dihydrochloride hydrate
type: Class
subclass of: hydrate
subclass of: CHEBI_36807
subclass of: Restriction
  on property: has part
  some values from: emetine dihydrochloride
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: emetic
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35820
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38068
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48001
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88230
definition: A hydrate that is the monohydrate of the dihydrochloride salt of emetine.
definition source: PMID: 24841273; PMID: 29557770
imported from: chebi.owl
charge: 0
formula: C29H40N2O4.H2O.ClH.ClH
inchi: InChI=1S/C29H40N2O4.2ClH.H2O/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;;;/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3;2*1H;1H2/t18-,21-,24+,25-;;;/m0.../s1
inchikey: IZTPMTAWOCEKKM-VXMYZLRESA-N
mass: 571.580
monoisotopicmass: 570.26273
database_cross_reference: CAS:7083-71-8
database_cross_reference: PMID:24107123
database_cross_reference: PMID:28257497
database_cross_reference: Reaxys:5216794
has exact synonym: (2S)-6',7',10,11-tetramethoxyemetan dihydrochloride--water (1/1)
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-6',7',10,11-tetramethoxyemetan dihydrochloride hydrate
has_related_synonym: (2S)-6',7',10,11-tetramethoxyemetan-2',5-diium dichloride--water (1/1)
has_related_synonym: emetine dihydrochloride monohydrate
has_related_synonym: emetine hydrochloride hydrate
id: CHEBI:146000
in subset: 3 STAR

levomethorphan
type: Class
subclass of: 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
subclass of: Restriction
  on property: has role
  some values from: opioid analgesic
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50266
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI 6444
subclass of: Restriction
  on property: is enantiomer of
  some values from: CHEBI 4470
definition: A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the stereocenters at positions 4a, 10 and 10a have R-configuration. It is a prodrug of levorphanol and a strong narcotic analgesic, and listed as a schedule II controlled substance.
imported from: chebi.owl
charge: 0
formula: C18H25NO
inchi: InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m0/s1
inchikey: MKXZASYAUGDDCJ-CGTJXYLNSA-N
mass: 271.404
monoisotopicmass: 271.19361
database_cross_reference: CAS:125-70-2
database_cross_reference: PMID:16870378
database_cross_reference: PMID:26226106
database_cross_reference: PMID:28867701
database_cross_reference: PMID:29131506
database_cross_reference: Wikipedia:Levomethorphan
has exact synonym: (4aR,10R,10aR)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
has exact synonym: 3-methoxy-17-methylmorphinan
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-3-methoxy-17-methylmorphinan
has_related_synonym: (-)-3-methoxy-N-methylmorphinan
has_related_synonym: L-3-methoxy-17-methylmorphinan
has_related_synonym: L-methorphan
has_related_synonym: levomethorphan
has_related_synonym: levomethorphane
has_related_synonym: levomethorphanum
has_related_synonym: levometorfano
id: CHEBI:146176
in subset: 3 STAR

6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
type: Class
subclass of: morphinane alkaloid
subclass of: aromatic ether
subclass of: CHEBI_38163
subclass of: CHEBI_83818
definition: An organic heterotetracyclic compound that is 1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene which is substituted by a methoxy group at position 6 and a methyl group at position 11.
imported from: chebi.owl
charge: 0
formula: C18H25NO
inchi: InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3
inchikey: MKXZASYAUGDDCJ-UHFFFAOYSA-N
mass: 271.404
monoisotopicmass: 271.19361
has exact synonym: 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0(1,10).0(2,7)]heptadeca-2(7),3,5-triene
has exact synonym: 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
has_obo_namespace: chebi_ontology
id: CHEBI:146178
in subset: 3 STAR

oneirogen
type: Class
subclass of: psychotropic drug
definition: Any substance that produces or enhances dream-like states of consciousness.
imported from: chebi.owl
database_cross_reference: Wikipedia:Oneirogen
has_obo_namespace: chebi_ontology
has_related_synonym: oneirogens
id: CHEBI:146270
in subset: 3 STAR

GS-441524
type: Class
subclass of: nitrile
subclass of: aromatic amine
subclass of: CHEBI_37086
subclass of: CHEBI_88341
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49103
definition: A C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV.
imported from: chebi.owl
charge: 0
formula: C12H13N5O4
inchi: InChI=1S/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/m1/s1
inchikey: BRDWIEOJOWJCLU-LTGWCKQJSA-N
mass: 291.267
monoisotopicmass: 291.09675
smiles: [C@]1(O[C@@H]([C@H]([C@H]1O)O)CO)(C#N)C=2N3N=CN=C(C3=CC2)N
database_cross_reference: CAS:1191237-69-0
database_cross_reference: PMID:22446091
database_cross_reference: PMID:28124907
database_cross_reference: PMID:29778200
database_cross_reference: PMID:30755068
has exact synonym: (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
has_obo_namespace: chebi_ontology
has_related_synonym: EVO 984
has_related_synonym: EVO-984
has_related_synonym: EVO984
has_related_synonym: GS 441524
has_related_synonym: GS441524
id: CHEBI:147281
in subset: 3 STAR

cinanserin(1+)
type: Class
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cinanserin
definition: An ammonium ion derivative that is the conjugate acid of cinanserin, obtained by the protonation of the tertiary amino group. It is the major microspecies at pH 7.3.
imported from: chebi.owl
charge: +1
formula: C20H25N2OS
inchi: InChI=1S/C20H24N2OS/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23)/p+1/b14-13+
inchikey: RSUVYMGADVXGOU-BUHFOSPRSA-O
mass: 341.490
monoisotopicmass: 341.16821
smiles: C=1(C=CC=CC1NC(=O)/C=C/C=2C=CC=CC2)SCCC[NH+](C)C
has exact synonym: N,N-dimethyl-3-[(2-{[(2E)-3-phenylprop-2-enoyl]amino}phenyl)sulfanyl]propan-1-aminium
has_obo_namespace: chebi_ontology
id: CHEBI:147283
in subset: 3 STAR

EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
type: Class
subclass of: CHEBI_76796
definition: An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
imported from: chebi.owl
database_cross_reference: Wikipedia:C30_Endopeptidase
has_obo_namespace: chebi_ontology
has_related_synonym: 3C-like protease inhibitor
has_related_synonym: 3C-like protease inhibitors
has_related_synonym: 3cLpro inhibitor
has_related_synonym: 3cLpro inhibitors
has_related_synonym: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors
has_related_synonym: EC 3.4.22.69 inhibitor
has_related_synonym: EC 3.4.22.69 inhibitors
has_related_synonym: Mpro inhibitor
has_related_synonym: Mpro inhibitors
has_related_synonym: SARS 3C-like protease inhibitor
has_related_synonym: SARS 3C-like protease inhibitors
has_related_synonym: SARS coronavirus 3CL protease inhibitor
has_related_synonym: SARS coronavirus 3CL protease inhibitors
has_related_synonym: SARS coronavirus main peptidase inhibitor
has_related_synonym: SARS coronavirus main peptidase inhibitors
has_related_synonym: SARS coronavirus main protease inhibitor
has_related_synonym: SARS coronavirus main protease inhibitors
has_related_synonym: SARS coronavirus main proteinase inhibitor
has_related_synonym: SARS coronavirus main proteinase inhibitors
has_related_synonym: SARS-CoV 3CLpro enzyme inhibitor
has_related_synonym: SARS-CoV 3CLpro enzyme inhibitors
has_related_synonym: SARS-CoV Mpro inhibitor
has_related_synonym: SARS-CoV Mpro inhibitors
has_related_synonym: SARS-CoV main protease inhibitor
has_related_synonym: SARS-CoV main protease inhibitors
has_related_synonym: coronavirus 3C-like protease inhibitor
has_related_synonym: coronavirus 3C-like protease inhibitors
has_related_synonym: severe acute respiratory syndrome coronavirus main protease inhibitor
has_related_synonym: severe acute respiratory syndrome coronavirus main protease inhibitors
id: CHEBI:147285
in subset: 3 STAR

SG85
type: Class
subclass of: secondary carboxamide
subclass of: ethyl ester
subclass of: ether
subclass of: CHEBI_51702
subclass of: CHEBI_74223
subclass of: CHEBI_84135
subclass of: CHEBI_84144
subclass of: CHEBI_90628
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of N-[(benzyloxy)carbonyl]-O-tert-butyl-L-serine with the primary amino group of ethyl (2E,4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-(L-phenylalanylamino)pent-2-enoate. It is a potent enterovirus 3C protease inhibitor with EC50 of 180 nM against enterovirus 71 (EV71) and 60 nM against human rhinovirus 14 in a live virus-cell-based assay.
definition source: PMID: 25039866; PMID: 27344959
imported from: chebi.owl
charge: 0
formula: C35H46N4O8
inchi: InChI=1S/C35H46N4O8/c1-5-45-30(40)17-16-27(21-26-18-19-36-31(26)41)37-32(42)28(20-24-12-8-6-9-13-24)38-33(43)29(23-47-35(2,3)4)39-34(44)46-22-25-14-10-7-11-15-25/h6-17,26-29H,5,18-23H2,1-4H3,(H,36,41)(H,37,42)(H,38,43)(H,39,44)/b17-16+/t26-,27+,28-,29-/m0/s1
inchikey: CTAXDRJNQQBEIB-VCJIVHKYSA-N
mass: 650.773
monoisotopicmass: 650.33156
database_cross_reference: CAS:1575662-24-6
database_cross_reference: PMID:23388726
database_cross_reference: PMID:25039866
database_cross_reference: PMID:25199773
database_cross_reference: PMID:26055377
database_cross_reference: PMID:27668727
has exact synonym: N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2S,3E)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-phenylalaninamide
has_obo_namespace: chebi_ontology
has_related_synonym: SG 85
has_related_synonym: SG-85
id: CHEBI:147346
in subset: 3 STAR

angiotensin (1-9) dizwitterion
type: Class
subclass of: CHEBI_60466
subclass of: Restriction
  on property: has role
  some values from: antihypertensive agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77307
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_86264
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_80128
definition: A peptide zwitterion that is the dizwitterionic form of angiotensin (1-9) having both carboxy groups deprotonated and the aspartyl amino group and arginine side-chain protonated. It is the major species at pH 7.3.
imported from: chebi.owl
charge: 0
formula: C56H78N16O13
inchi: InChI=1S/C56H78N16O13/c1-5-31(4)46(71-50(79)40(22-33-15-17-36(73)18-16-33)67-52(81)45(30(2)3)70-48(77)38(13-9-19-62-56(58)59)65-47(76)37(57)25-44(74)75)53(82)68-41(23-34-26-60-28-63-34)54(83)72-20-10-14-43(72)51(80)66-39(21-32-11-7-6-8-12-32)49(78)69-42(55(84)85)24-35-27-61-29-64-35/h6-8,11-12,15-18,26-31,37-43,45-46,73H,5,9-10,13-14,19-25,57H2,1-4H3,(H,60,63)(H,61,64)(H,65,76)(H,66,80)(H,67,81)(H,68,82)(H,69,78)(H,70,77)(H,71,79)(H,74,75)(H,84,85)(H4,58,59,62)/t31-,37-,38-,39-,40-,41-,42-,43-,45-,46-/m0/s1
inchikey: LJXGOQOPNPFXFT-JWRYNVNRSA-N
mass: 1183.339
monoisotopicmass: 1182.59343
database_cross_reference: PMID:10969042
database_cross_reference: PMID:24593683
database_cross_reference: PMID:30179588
database_cross_reference: PMID:32152556
has exact synonym: N(5)-[amino(iminio)methyl]-N(2)-[(2S)-2-azaniumyl-3-carboxylatopropanoyl]-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-N-[(1S)-1-carboxylato-2-(1H-imidazol-4-yl)ethyl]-L-phenylalaninamide
has exact synonym: angiotensin (1-9) dizwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His
has_related_synonym: angiotensin-(1-9)
has_related_synonym: angiotensin-(1-9) dizwitterion
id: CHEBI:147351
in subset: 3 STAR

chloroquine(2+)
type: Class
subclass of: tertiary ammonium ion
subclass of: CHEBI_52837
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI 3638
definition: A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3.
imported from: chebi.owl
charge: +2
formula: C18H28ClN3
inchi: InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)/p+2
inchikey: WHTVZRBIWZFKQO-UHFFFAOYSA-P
mass: 321.890
monoisotopicmass: 321.19608
smiles: [NH+]1=CC=C(C=2C1=CC(Cl)=CC2)NC(CCC[NH+](CC)CC)C
database_cross_reference: PMID:25693996
has exact synonym: 7-chloro-4-{[5-(diethylazaniumyl)pentan-2-yl]amino}quinolinium
has_obo_namespace: chebi_ontology
has_related_synonym: chloroquine dication
has_related_synonym: di-protonated chloroquine
id: CHEBI:149484
in subset: 3 STAR

emetine(2+)
type: Class
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI 4781
definition: An ammonium ion derivative obtained from protonation of the nitrogens of emetine. It is the major species at pH 7.3.
imported from: chebi.owl
charge: +2
formula: C29H42N2O4
inchi: InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/p+2/t18-,21-,24+,25-/m0/s1
inchikey: AUVVAXYIELKVAI-CKBKHPSWSA-P
mass: 482.664
monoisotopicmass: 482.31336
database_cross_reference: MetaCyc:CPD-14817
database_cross_reference: PMID:5985282
has exact synonym: (2S)-6',7',10,11-tetramethoxyemetan-2',5-diium
has_obo_namespace: chebi_ontology
has_related_synonym: emetine dication
id: CHEBI:149548
in subset: 3 STAR

emetine dihydrochloride
type: Class
subclass of: CHEBI_36807
subclass of: Restriction
  on property: has part
  some values from: emetine(2+)
subclass of: Restriction
  on property: has role
  some values from: emetic
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35820
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38068
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48001
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88230
definition: The dihydrochloride salt of emetine.
imported from: chebi.owl
charge: 0
formula: C29H40N2O4.ClH.ClH
inchi: InChI=1S/C29H40N2O4.2ClH/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;;/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3;2*1H/t18-,21-,24+,25-;;/m0../s1
inchikey: JROGBPMEKVAPEH-GXGBFOEMSA-N
mass: 553.570
monoisotopicmass: 552.25216
database_cross_reference: CAS:316-42-7
database_cross_reference: KEGG:D03985
database_cross_reference: PMID:11294031
database_cross_reference: PMID:13904259
database_cross_reference: PMID:14266439
database_cross_reference: PMID:14852643
database_cross_reference: PMID:24045224
database_cross_reference: PMID:24107123
database_cross_reference: PMID:28257497
database_cross_reference: PMID:31964796
database_cross_reference: PMID:3668005
database_cross_reference: PMID:4042936
database_cross_reference: PMID:4204205
database_cross_reference: PMID:4245434
database_cross_reference: PMID:4399461
database_cross_reference: PMID:4705155
database_cross_reference: PMID:4929936
database_cross_reference: PMID:5495495
database_cross_reference: PMID:5538625
database_cross_reference: PMID:5642979
database_cross_reference: PMID:5862615
database_cross_reference: PMID:5957731
database_cross_reference: PMID:616384
database_cross_reference: PMID:8789394
database_cross_reference: PMID:891868
database_cross_reference: PMID:9388036
database_cross_reference: PMID:94222
has exact synonym: (2S)-6',7',10,11-tetramethoxyemetan dihydrochloride
has_obo_namespace: chebi_ontology
has_related_synonym: emetine HCl
has_related_synonym: emetine dihydrochloride anhydrous
has_related_synonym: emetine hydrochloride
id: CHEBI:149551
in subset: 3 STAR

emetic
type: Class
subclass of: drug
definition: Any agent that induces nausea and vomiting.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: emetics
id: CHEBI:149552
in subset: 3 STAR

anticoronaviral agent
type: Class
subclass of: antiviral agent
definition: Any antiviral agent which inhibits the activity of coronaviruses.
imported from: chebi.owl
database_cross_reference: Wikipedia:Coronavirus
has exact synonym: anticoronaviral agent
has_obo_namespace: chebi_ontology
has_related_synonym: anti-coronaviral agent
has_related_synonym: anti-coronaviral agents
has_related_synonym: anti-coronavirus agent
has_related_synonym: anti-coronavirus agents
has_related_synonym: anticoronaviral agents
has_related_synonym: anticoronaviral drug
has_related_synonym: anticoronaviral drugs
has_related_synonym: anticoronavirus agent
has_related_synonym: anticoronavirus agents
has_related_synonym: anticoronviral agent
has_related_synonym: anticoronviral agents
id: CHEBI:149553
in subset: 3 STAR

hydroxychloroquine(2+)
type: Class
subclass of: tertiary ammonium ion
subclass of: CHEBI_52837
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI 5801
definition: A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug hydroxychloroquine. It is the major species at pH 7.3.
imported from: chebi.owl
charge: +2
formula: C18H28ClN3O
inchi: InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2
inchikey: XXSMGPRMXLTPCZ-UHFFFAOYSA-P
mass: 337.890
monoisotopicmass: 337.19099
smiles: C=12C(NC(CCC[NH+](CCO)CC)C)=CC=[NH+]C1C=C(C=C2)Cl
database_cross_reference: PMID:25693996
has exact synonym: 7-chloro-4-({5-[ethyl(2-hydroxyethyl)azaniumyl]pentan-2-yl}amino)quinolinium
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxychloroquine dication
id: CHEBI:149564
in subset: 3 STAR

sulfide(2-)
type: Class
subclass of: CHEBI_79388
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrosulfide
definition: A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide.
imported from: chebi.owl
charge: -2
formula: S
inchi: InChI=1S/S/q-2
inchikey: UCKMPCXJQFINFW-UHFFFAOYSA-N
mass: 32.06600
monoisotopicmass: 31.97317
smiles: [S--]
database_cross_reference: CAS:18496-25-8
database_cross_reference: UM-BBD_compID:c0569
has exact synonym: sulfanediide
has exact synonym: sulfide(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: S(2-)
has_related_synonym: Sulfide
has_related_synonym: sulphide
id: CHEBI:15138
in subset: 3 STAR

acceptor
type: Class
subclass of: CHEBI_51086
definition: A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
imported from: chebi.owl
has_alternative_id: CHEBI:13699
has_alternative_id: CHEBI:2377
database_cross_reference: KEGG:C00028
database_cross_reference: KEGG:C16722
has exact synonym: Acceptor
has_obo_namespace: chebi_ontology
has_related_synonym: A
has_related_synonym: Akzeptor
has_related_synonym: Hydrogen-acceptor
has_related_synonym: Oxidized donor
has_related_synonym: accepteur
id: CHEBI:15339
in subset: 3 STAR

cysteine
type: Class
subclass of: polar amino acid
subclass of: sulfur-containing amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50326
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: cysteinium
subclass of: Restriction
  on property: is tautomer of
  some values from: cysteine zwitterion
definition: A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
inchikey: XUJNEKJLAYXESH-UHFFFAOYSA-N
mass: 121.15922
monoisotopicmass: 121.01975
smiles: NC(CS)C(O)=O
has_alternative_id: CHEBI:14061
has_alternative_id: CHEBI:23508
has_alternative_id: CHEBI:4050
database_cross_reference: Beilstein:1721406
database_cross_reference: CAS:3374-22-9
database_cross_reference: Gmelin:2933
database_cross_reference: KEGG:C00736
database_cross_reference: KNApSAcK:C00001351
database_cross_reference: KNApSAcK:C00007323
database_cross_reference: PMID:17439666
database_cross_reference: PMID:25181601
database_cross_reference: Reaxys:1721406
database_cross_reference: Wikipedia:Cysteine
has exact synonym: Cysteine
has exact synonym: cysteine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-3-mercaptopropionic acid
has_related_synonym: 2-amino-3-mercaptopropanoic acid
has_related_synonym: 2-amino-3-sulfanylpropanoic acid
has_related_synonym: C
has_related_synonym: Cys
has_related_synonym: Cystein
has_related_synonym: Hcys
has_related_synonym: Zystein
has_related_synonym: cisteina
id: CHEBI:15356
in subset: 3 STAR

acetic acid
type: Class
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48356
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64049
subclass of: Restriction
  on property: has role
  some values from: CHEBI_65256
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: acetate
definition: A simple monocarboxylic acid containing two carbons.
imported from: chebi.owl
charge: 0
formula: C2H4O2
inchi: InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
inchikey: QTBSBXVTEAMEQO-UHFFFAOYSA-N
mass: 60.05200
monoisotopicmass: 60.02113
smiles: CC(O)=O
has_alternative_id: CHEBI:22169
has_alternative_id: CHEBI:2387
has_alternative_id: CHEBI:40486
database_cross_reference: Beilstein:506007
database_cross_reference: CAS:64-19-7
database_cross_reference: Drug_Central:4211
database_cross_reference: Gmelin:1380
database_cross_reference: HMDB:HMDB0000042
database_cross_reference: KEGG:C00033
database_cross_reference: KEGG:D00010
database_cross_reference: KNApSAcK:C00001176
database_cross_reference: LIPID_MAPS_instance:LMFA01010002
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PDBeChem:ACY
database_cross_reference: PMID:12005138
database_cross_reference: PMID:15107950
database_cross_reference: PMID:16630552
database_cross_reference: PMID:16774200
database_cross_reference: PMID:17190852
database_cross_reference: PMID:19416101
database_cross_reference: PMID:19469536
database_cross_reference: PMID:22153255
database_cross_reference: PMID:22173419
database_cross_reference: PPDB:1333
database_cross_reference: Reaxys:506007
database_cross_reference: Wikipedia:Acetic_acid
has exact synonym: ACETIC ACID
has exact synonym: Acetic acid
has exact synonym: acetic acid
has_obo_namespace: chebi_ontology
has_related_synonym: AcOH
has_related_synonym: CH3-COOH
has_related_synonym: CH3CO2H
has_related_synonym: E 260
has_related_synonym: E-260
has_related_synonym: E260
has_related_synonym: Essigsaeure
has_related_synonym: Ethanoic acid
has_related_synonym: Ethylic acid
has_related_synonym: HOAc
has_related_synonym: INS No. 260
has_related_synonym: MeCO2H
has_related_synonym: MeCOOH
has_related_synonym: Methanecarboxylic acid
has_related_synonym: acide acetique
has_related_synonym: ethoic acid
id: CHEBI:15366
in subset: 3 STAR

water
type: Class
subclass of: oxygen hydride
subclass of: CHEBI_37176
subclass of: CHEBI_52625
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48360
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76413
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydroxide
subclass of: Restriction
  on property: is conjugate base of
  some values from: oxonium
definition: An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms.
imported from: chebi.owl
charge: 0
formula: H2O
inchi: InChI=1S/H2O/h1H2
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-N
mass: 18.01530
monoisotopicmass: 18.01056
smiles: [H]O[H]
has_alternative_id: CHEBI:10743
has_alternative_id: CHEBI:13352
has_alternative_id: CHEBI:27313
has_alternative_id: CHEBI:42043
has_alternative_id: CHEBI:42857
has_alternative_id: CHEBI:43228
has_alternative_id: CHEBI:44292
has_alternative_id: CHEBI:44701
has_alternative_id: CHEBI:44819
has_alternative_id: CHEBI:5585
database_cross_reference: Beilstein:3587155
database_cross_reference: CAS:7732-18-5
database_cross_reference: Gmelin:117
database_cross_reference: HMDB:HMDB0002111
database_cross_reference: KEGG:C00001
database_cross_reference: KEGG:D00001
database_cross_reference: MetaCyc:WATER
database_cross_reference: MolBase:1
database_cross_reference: PDBeChem:HOH
database_cross_reference: Reaxys:3587155
database_cross_reference: Wikipedia:Water
has exact synonym: WATER
has exact synonym: Water
has exact synonym: oxidane
has exact synonym: water
has_obo_namespace: chebi_ontology
has_related_synonym: BOUND WATER
has_related_synonym: H2O
has_related_synonym: HOH
has_related_synonym: Wasser
has_related_synonym: [OH2]
has_related_synonym: acqua
has_related_synonym: agua
has_related_synonym: aqua
has_related_synonym: dihydridooxygen
has_related_synonym: dihydrogen oxide
has_related_synonym: eau
has_related_synonym: hydrogen hydroxide
id: CHEBI:15377
in subset: 3 STAR

glycine
type: Class
subclass of: serine family amino acid
subclass of: alpha-amino acid
subclass of: CHEBI_83813
definition: The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain.
imported from: chebi.owl
charge: 0
formula: C2H5NO2
inchi: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
inchikey: DHMQDGOQFOQNFH-UHFFFAOYSA-N
mass: 75.06664
monoisotopicmass: 75.03203
smiles: NCC(O)=O
has_alternative_id: CHEBI:10792
has_alternative_id: CHEBI:14344
has_alternative_id: CHEBI:24368
has_alternative_id: CHEBI:42964
has_alternative_id: CHEBI:5460
database_cross_reference: Beilstein:635782
database_cross_reference: CAS:56-40-6
database_cross_reference: DrugBank:DB00145
database_cross_reference: Drug_Central:1319
database_cross_reference: ECMDB:ECMDB00123
database_cross_reference: Gmelin:1808
database_cross_reference: HMDB:HMDB0000123
database_cross_reference: KEGG:C00037
database_cross_reference: KEGG:D00011
database_cross_reference: KNApSAcK:C00001361
database_cross_reference: MetaCyc:GLY
database_cross_reference: PDBeChem:GLY
database_cross_reference: PMID:10930630
database_cross_reference: PMID:11019925
database_cross_reference: PMID:11174716
database_cross_reference: PMID:11542461
database_cross_reference: PMID:11806864
database_cross_reference: PMID:12631515
database_cross_reference: PMID:12754315
database_cross_reference: PMID:12770151
database_cross_reference: PMID:12921899
database_cross_reference: PMID:15331688
database_cross_reference: PMID:15388434
database_cross_reference: PMID:15710237
database_cross_reference: PMID:16105183
database_cross_reference: PMID:16151895
database_cross_reference: PMID:16214212
database_cross_reference: PMID:16417482
database_cross_reference: PMID:16444815
database_cross_reference: PMID:16664855
database_cross_reference: PMID:16901953
database_cross_reference: PMID:16918424
database_cross_reference: PMID:16986325
database_cross_reference: PMID:16998855
database_cross_reference: PMID:17154252
database_cross_reference: PMID:17383967
database_cross_reference: PMID:17582620
database_cross_reference: PMID:17970719
database_cross_reference: PMID:18079355
database_cross_reference: PMID:18396796
database_cross_reference: PMID:18440992
database_cross_reference: PMID:18593588
database_cross_reference: PMID:18816054
database_cross_reference: PMID:18840508
database_cross_reference: PMID:19028609
database_cross_reference: PMID:19120667
database_cross_reference: PMID:19449910
database_cross_reference: PMID:19526731
database_cross_reference: PMID:19544666
database_cross_reference: PMID:19738917
database_cross_reference: PMID:19916621
database_cross_reference: PMID:19924257
database_cross_reference: PMID:21751272
database_cross_reference: PMID:22044190
database_cross_reference: PMID:22079563
database_cross_reference: PMID:22234938
database_cross_reference: PMID:22264337
database_cross_reference: PMID:22293292
database_cross_reference: PMID:22401276
database_cross_reference: PMID:22434786
database_cross_reference: Reaxys:635782
database_cross_reference: Wikipedia:Glycine

L-leucine
type: Class
subclass of: L-alpha-amino acid
subclass of: leucine
subclass of: pyruvate family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-leucinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-leucinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-leucine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57427
definition: The L-enantiomer of leucine.
imported from: chebi.owl
charge: 0
formula: C6H13NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
inchikey: ROHFNLRQFUQHCH-YFKPBYRVSA-N
mass: 131.17296
monoisotopicmass: 131.09463
smiles: CC(C)C[C@H](N)C(O)=O
has_alternative_id: CHEBI:10866
has_alternative_id: CHEBI:13131
has_alternative_id: CHEBI:21348
has_alternative_id: CHEBI:43646
has_alternative_id: CHEBI:43695
has_alternative_id: CHEBI:43733
has_alternative_id: CHEBI:43814
has_alternative_id: CHEBI:6260
database_cross_reference: Beilstein:1721722
database_cross_reference: CAS:61-90-5
database_cross_reference: DrugBank:DB00149
database_cross_reference: Drug_Central:1557
database_cross_reference: ECMDB:ECMDB00687
database_cross_reference: Gmelin:50204
database_cross_reference: HMDB:HMDB0000687
database_cross_reference: KEGG:C00123
database_cross_reference: KEGG:D00030
database_cross_reference: KNApSAcK:C00001377
database_cross_reference: MetaCyc:LEU
database_cross_reference: PDBeChem:LEU_LFOH
database_cross_reference: PMID:17609475
database_cross_reference: PMID:22735334
database_cross_reference: PMID:24206068
database_cross_reference: PMID:24333966
database_cross_reference: PMID:8798704
database_cross_reference: Reaxys:1721722
database_cross_reference: Wikipedia:Leucine
database_cross_reference: YMDB:YMDB00387
has exact synonym: L-Leucine
has exact synonym: L-leucine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-4-methylpentanoic acid
has_related_synonym: (2S)-alpha-2-Amino-4-methylvaleric acid
has_related_synonym: (2S)-alpha-Leucine
has_related_synonym: (S)-(+)-leucine
has_related_synonym: (S)-leucine
has_related_synonym: 2-Amino-4-methylvaleric acid
has_related_synonym: L
has_related_synonym: L-Leucin
has_related_synonym: L-Leuzin
has_related_synonym: LEUCINE
has_related_synonym: Leu
id: CHEBI:15603
in subset: 3 STAR

5-formyltetrahydrofolic acid
type: Class
subclass of: formyltetrahydrofolic acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: inhibitor
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_65340
definition: A formyltetrahydrofolic acid in which the formyl group is located at position 5.
definition source: Reference: PMID: 26885694
imported from: chebi.owl
charge: 0
formula: C20H23N7O7
inchi: InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1
inchikey: VVIAGPKUTFNRDU-ABLWVSNPSA-N
mass: 473.43930
monoisotopicmass: 473.16590
has_alternative_id: CHEBI:12127
has_alternative_id: CHEBI:18607
has_alternative_id: CHEBI:2057
database_cross_reference: CAS:58-05-9
database_cross_reference: DrugBank:DB03256
database_cross_reference: Drug_Central:1232
database_cross_reference: KEGG:C03479
database_cross_reference: KEGG:D07986
database_cross_reference: LINCS:LSM-5146
database_cross_reference: Reaxys:101688
database_cross_reference: Wikipedia:Folinic_acid
has exact synonym: N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
has_related_synonym: 10-Formyl-7,8-dihydrofolic acid
has_related_synonym: 5-Formyl-5,6,7,8-tetrahydrofolic acid
has_related_synonym: 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
has_related_synonym: 5-Formyltetrahydrofolate
has_related_synonym: Acide folinique
has_related_synonym: Folinic acid
has_related_synonym: L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
has_related_synonym: Leucovorin
has_related_synonym: Leucovorinum
has_related_synonym: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
has_related_synonym: N5-Formyl-5,6,7,8-tetrahydrofolic acid
has_related_synonym: N5-Formyltetrahydrofolic acid
has_related_synonym: folinate
id: CHEBI:15640
in subset: 3 STAR

L-alpha-amino acid
type: Class
subclass of: alpha-amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_59814
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_59869
definition: Any alpha-amino acid having L-configuration at the alpha-carbon.
imported from: chebi.owl
charge: 0
formula: C2H4NO2R
mass: 74.05870
monoisotopicmass: 74.02420
smiles: N[C@@H]([*])C(O)=O
has_alternative_id: CHEBI:13072
has_alternative_id: CHEBI:13243
has_alternative_id: CHEBI:13797
has_alternative_id: CHEBI:21224
has_alternative_id: CHEBI:6175
database_cross_reference: KEGG:C00151
has exact synonym: L-alpha-amino acid
has exact synonym: L-alpha-amino acids
has_obo_namespace: chebi_ontology
has_related_synonym: L-2-Amino acid
has_related_synonym: L-Amino acid
has_related_synonym: L-alpha-amino acids
id: CHEBI:15705
in subset: 3 STAR

primary alcohol
type: Class
subclass of: alcohol
definition: A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
imported from: chebi.owl
charge: 0
formula: CH3OR
mass: 31.034
monoisotopicmass: 31.01839
smiles: *C(O)([H])[H]
has_alternative_id: CHEBI:13676
has_alternative_id: CHEBI:14887
has_alternative_id: CHEBI:26262
has_alternative_id: CHEBI:57489
has_alternative_id: CHEBI:8406
database_cross_reference: KEGG:C00226
has exact synonym: Primary alcohol
has_obo_namespace: chebi_ontology
has_related_synonym: 1-Alcohol
has_related_synonym: a primary alcohol
has_related_synonym: primary alcohols
id: CHEBI:15734
in subset: 3 STAR

staurosporine
type: Class
subclass of: CHEBI_37697
subclass of: CHEBI_38165
subclass of: Restriction
  on property: has role
  some values from: geroprotector
subclass of: Restriction
  on property: has role
  some values from: CHEBI_37700
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_57491
imported from: chebi.owl
charge: 0
formula: C28H26N4O3
inchi: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
inchikey: HKSZLNNOFSGOKW-FYTWVXJKSA-N
mass: 466.541
monoisotopicmass: 466.20049
has_alternative_id: CHEBI:15106
has_alternative_id: CHEBI:45788
has_alternative_id: CHEBI:9252
database_cross_reference: CAS:62996-74-1
database_cross_reference: DrugBank:DB02010
database_cross_reference: KEGG:C02079
database_cross_reference: KNApSAcK:C00018127
database_cross_reference: LINCS:LSM-1103
database_cross_reference: PDBeChem:STU
database_cross_reference: PMID:15613975
database_cross_reference: PMID:15682296
database_cross_reference: PMID:18478334
database_cross_reference: PMID:22363408
database_cross_reference: PMID:32800439
database_cross_reference: PMID:34428735
database_cross_reference: Wikipedia:Staurosporine
has exact synonym: (5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
has exact synonym: Staurosporine
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-Staurosporine
has_related_synonym: AM-2282
has_related_synonym: STS
has_related_synonym: Staurosporin
has_related_synonym: antibiotic AM 2282
id: CHEBI:15738
in subset: 3 STAR

formate
type: Class
subclass of: CHEBI_35757
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: formic acid
definition: A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects.
imported from: chebi.owl
charge: -1
formula: CHO2
inchi: InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1
inchikey: BDAGIHXWWSANSR-UHFFFAOYSA-M
mass: 45.01744
monoisotopicmass: 44.99820
smiles: [H]C([O-])=O
has_alternative_id: CHEBI:14276
has_alternative_id: CHEBI:24081
database_cross_reference: Beilstein:1901205
database_cross_reference: CAS:71-47-6
database_cross_reference: Gmelin:1006
database_cross_reference: HMDB:HMDB0000142
database_cross_reference: KEGG:C00058
database_cross_reference: MetaCyc:FORMATE
database_cross_reference: PMID:17190852
database_cross_reference: PMID:3946945
database_cross_reference: Reaxys:1901205
database_cross_reference: UM-BBD_compID:c0106
database_cross_reference: Wikipedia:Formate
has exact synonym: formate
has_obo_namespace: chebi_ontology
has_related_synonym: HCO2 anion
has_related_synonym: aminate
has_related_synonym: formiate
has_related_synonym: formic acid, ion(1-)
has_related_synonym: formylate
has_related_synonym: hydrogen carboxylate
has_related_synonym: methanoate
id: CHEBI:15740
in subset: 3 STAR

N-acyl-D-amino acid
type: Class
subclass of: CHEBI_51569
subclass of: CHEBI_83812
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_59876
subclass of: Restriction
  on property: is enantiomer of
  some values from: N-acyl-L-amino acid
definition: Any N-acyl-amino acid in which the amino acid moiety has D configuration.
imported from: chebi.owl
charge: 0
formula: C3H3NO3R2
mass: 101.06080
monoisotopicmass: 101.01129
smiles: OC(=O)[C@@H]([*])NC([*])=O
has_alternative_id: CHEBI:12474
has_alternative_id: CHEBI:21631
has_alternative_id: CHEBI:7224
has_obo_namespace: chebi_ontology
id: CHEBI:15778
in subset: 3 STAR

N-(long-chain-acyl)ethanolamine
type: Class
subclass of: N-(fatty acyl)-ethanolamine
definition: Any N-acylethanolamine in which the acyl group has a chain length of C12 or greater.
imported from: chebi.owl
charge: 0
formula: C3H6NO2R
mass: 88.085
monoisotopicmass: 88.03985
smiles: OCCNC([*])=O
has_alternative_id: CHEBI:12537
has_alternative_id: CHEBI:21485
has_alternative_id: CHEBI:7099
has_obo_namespace: chebi_ontology
has_related_synonym: N-(long-chain fatty acyl)ethanolamine
id: CHEBI:15897
in subset: 3 STAR

long-chain fatty acid
type: Class
subclass of: fatty acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_57560
definition: A fatty acid with a chain length ranging from C13 to C22.
imported from: chebi.owl
charge: 0
formula: CHO2R
mass: 45.017
monoisotopicmass: 44.99765
smiles: OC([*])=O
has_alternative_id: CHEBI:13655
has_alternative_id: CHEBI:14529
has_alternative_id: CHEBI:25075
has_alternative_id: CHEBI:6528
database_cross_reference: KEGG:C00638
has exact synonym: Long-chain fatty acid
has_obo_namespace: chebi_ontology
has_related_synonym: Higher fatty acid
has_related_synonym: LCFA
has_related_synonym: LCFAs
has_related_synonym: long-chain fatty acids
id: CHEBI:15904
in subset: 3 STAR

glycyrrhizinic acid
type: Class
subclass of: glucosiduronic acid
subclass of: pentacyclic triterpenoid
subclass of: tricarboxylic acid
subclass of: CHEBI_51689
subclass of: CHEBI_61778
subclass of: Restriction
  on property: has role
  some values from: CHEBI_65232
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glycyrrhizinate(3-)
definition: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.
imported from: chebi.owl
charge: 0
formula: C42H62O16
inchi: InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
inchikey: LPLVUJXQOOQHMX-QWBHMCJMSA-N
mass: 822.93210
monoisotopicmass: 822.40379
has_alternative_id: CHEBI:24418
has_alternative_id: CHEBI:5508
database_cross_reference: Beilstein:77922
database_cross_reference: CAS:1405-86-3
database_cross_reference: Drug_Central:1325
database_cross_reference: HMDB:HMDB0029843
database_cross_reference: KEGG:C02284
database_cross_reference: LIPID_MAPS_instance:LMPR0106150013
database_cross_reference: MetaCyc:GLYCYRRHIZINATE
database_cross_reference: PMID:11282481
database_cross_reference: PMID:15013279
database_cross_reference: PMID:24497916
database_cross_reference: Reaxys:77922
database_cross_reference: Wikipedia:Glycyrrhizin
has exact synonym: 30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosiduronic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
has_related_synonym: Glycyrrhizic acid
has_related_synonym: Glycyrrhizin
has_related_synonym: glycyrrhizic acid
id: CHEBI:15939
in subset: 3 STAR

O-acetylcarnitinium
type: Class
subclass of: quaternary ammonium ion
subclass of: Restriction
  on property: has role
  some values from: inhibitor
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_39547
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_73024
definition source: Reference: PMID: 30074795
imported from: chebi.owl
charge: +1
formula: C9H18NO4
inchi: InChI=1S/C9H17NO4/c1-7(11)14-8(5-9(12)13)6-10(2,3)4/h8H,5-6H2,1-4H3/p+1/t8-/m1/s1
inchikey: RDHQFKQIGNGIED-MRVPVSSYSA-O
mass: 204.24356
monoisotopicmass: 204.12303
smiles: CC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
has_alternative_id: CHEBI:12711
has_alternative_id: CHEBI:21936
has_alternative_id: CHEBI:7669
database_cross_reference: KEGG:C02571
has exact synonym: (2R)-2-(acetyloxy)-3-carboxy-N,N,N-trimethylpropan-1-aminium
has_obo_namespace: chebi_ontology
has_related_synonym: O-Acetyl-L-carnitine
has_related_synonym: O-Acetylcarnitine
id: CHEBI:15960
in subset: 3 STAR

D-glutamic acid
type: Class
subclass of: D-alpha-amino acid
subclass of: glutamic acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-glutamate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-glutamic acid
definition: An optically active form of glutamic acid having D-configuration.
imported from: chebi.owl
charge: 0
formula: C5H9NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
inchikey: WHUUTDBJXJRKMK-GSVOUGTGSA-N
mass: 147.12930
monoisotopicmass: 147.05316
smiles: N[C@H](CCC(O)=O)C(O)=O
has_alternative_id: CHEBI:21023
has_alternative_id: CHEBI:4183
database_cross_reference: Beilstein:1723800
database_cross_reference: CAS:6893-26-1
database_cross_reference: DrugBank:DB02517
database_cross_reference: Gmelin:201189
database_cross_reference: HMDB:HMDB0003339
database_cross_reference: KEGG:C00217
database_cross_reference: KNApSAcK:C00019577
database_cross_reference: MetaCyc:D-GLT
database_cross_reference: PDBeChem:DGL
database_cross_reference: Reaxys:1723800
has exact synonym: (2R)-2-aminopentanedioic acid
has exact synonym: D-Glutamic acid
has exact synonym: D-glutamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (R)-2-aminopentanedioic acid
has_related_synonym: D-2-Aminoglutaric acid
has_related_synonym: D-Glutaminic acid
has_related_synonym: D-Glutaminsaeure
has_related_synonym: DGL
has_related_synonym: glutamic acid D-form
id: CHEBI:15966
in subset: 3 STAR

ethanolamine
type: Class
subclass of: primary alcohol
subclass of: ethanolamines
subclass of: primary amine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_57603
definition: A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.
imported from: chebi.owl
charge: 0
formula: C2H7NO
inchi: InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
inchikey: HZAXFHJVJLSVMW-UHFFFAOYSA-N
mass: 61.08312
monoisotopicmass: 61.05276
smiles: NCCO
has_alternative_id: CHEBI:14223
has_alternative_id: CHEBI:23979
has_alternative_id: CHEBI:272066
has_alternative_id: CHEBI:42323
has_alternative_id: CHEBI:4880
database_cross_reference: Beilstein:505944
database_cross_reference: CAS:141-43-5
database_cross_reference: DrugBank:DB03994
database_cross_reference: Gmelin:1650
database_cross_reference: HMDB:HMDB0000149
database_cross_reference: KEGG:C00189
database_cross_reference: KEGG:D05074
database_cross_reference: KNApSAcK:C00007279
database_cross_reference: PDBeChem:ETA
database_cross_reference: PMID:10930630
database_cross_reference: PMID:12834252
database_cross_reference: PMID:15149650
database_cross_reference: PMID:24023812
database_cross_reference: PMID:3654008
database_cross_reference: PMID:6196640
database_cross_reference: PMID:6708049
database_cross_reference: Reaxys:505944
database_cross_reference: UM-BBD_compID:c0594
database_cross_reference: Wikipedia:Ethanolamine
has exact synonym: 2-aminoethanol
has exact synonym: Ethanolamine
has_obo_namespace: chebi_ontology
has_related_synonym: 1-amino-2-hydroxyethane
has_related_synonym: 2-Amino-ethanol
has_related_synonym: 2-Hydroxyethylamine
has_related_synonym: 2-amino-1-ethanol
has_related_synonym: 2-aminoethan-1-ol
has_related_synonym: 2-aminoethyl alcohol
has_related_synonym: Aethanolamin
has_related_synonym: Aminoethanol
has_related_synonym: ETA
has_related_synonym: Hea
has_related_synonym: MEA
has_related_synonym: MONOETHANOLAMINE
has_related_synonym: beta-aminoethanol
has_related_synonym: beta-aminoethyl alcohol
has_related_synonym: beta-ethanolamine
has_related_synonym: beta-hydroxyethylamine
has_related_synonym: colamine
has_related_synonym: glycinol
has_related_synonym: monoethanolamine
id: CHEBI:16000
in subset: 3 STAR

L-glutamic acid
type: Class
subclass of: L-alpha-amino acid
subclass of: glutamic acid
subclass of: glutamine family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: ferroptosis inducer
subclass of: Restriction
  on property: has role
  some values from: neurotransmitter
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-glutamate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-glutamic acid
definition: An optically active form of glutamic acid having L-configuration.
imported from: chebi.owl
charge: 0
formula: C5H9NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
inchikey: WHUUTDBJXJRKMK-VKHMYHEASA-N
mass: 147.12930
monoisotopicmass: 147.05316
smiles: N[C@@H](CCC(O)=O)C(O)=O
has_alternative_id: CHEBI:21304
has_alternative_id: CHEBI:42825
has_alternative_id: CHEBI:6224
database_cross_reference: BPDB:2297
database_cross_reference: Beilstein:1723801
database_cross_reference: CAS:56-86-0
database_cross_reference: DrugBank:DB00142
database_cross_reference: Drug_Central:1310
database_cross_reference: Gmelin:3502
database_cross_reference: HMDB:HMDB0000148
database_cross_reference: KEGG:C00025
database_cross_reference: KEGG:D00007
database_cross_reference: KNApSAcK:C00001358
database_cross_reference: LINCS:LSM-36375
database_cross_reference: MetaCyc:GLT
database_cross_reference: PDBeChem:GLU_LFOH
database_cross_reference: PMID:15739367
database_cross_reference: PMID:15930465
database_cross_reference: PMID:16719819
database_cross_reference: PMID:16892196
database_cross_reference: PMID:19581495
database_cross_reference: PMID:22219301
database_cross_reference: PMID:22735334
database_cross_reference: Reaxys:1723801
database_cross_reference: Wikipedia:L-Glutamic_Acid
has exact synonym: (2S)-2-aminopentanedioic acid
has exact synonym: L-Glutamic acid
has exact synonym: L-glutamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (S)-2-aminopentanedioic acid
has_related_synonym: (S)-glutamic acid
has_related_synonym: E
has_related_synonym: GLUTAMIC ACID
has_related_synonym: Glu
has_related_synonym: Glutamate
has_related_synonym: L-Glu
has_related_synonym: L-Glutaminic acid
has_related_synonym: L-Glutaminsaeure
has_related_synonym: acide glutamique
has_related_synonym: acido glutamico
has_related_synonym: acidum glutamicum
has_related_synonym: glutamic acid
id: CHEBI:16015
in subset: 3 STAR

cytosine
type: Class
subclass of: pyrimidine nucleobase
subclass of: CHEBI_38337
subclass of: CHEBI_38338
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
definition: An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4.
imported from: chebi.owl
charge: 0
formula: C4H5N3O
inchi: InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
inchikey: OPTASPLRGRRNAP-UHFFFAOYSA-N
mass: 111.10212
monoisotopicmass: 111.04326
smiles: Nc1cc[nH]c(=O)n1
has_alternative_id: CHEBI:14066
has_alternative_id: CHEBI:23531
has_alternative_id: CHEBI:4072
has_alternative_id: CHEBI:41732
database_cross_reference: Beilstein:2637
database_cross_reference: CAS:71-30-7
database_cross_reference: Gmelin:82472
database_cross_reference: HMDB:HMDB0000630
database_cross_reference: KEGG:C00380
database_cross_reference: KNApSAcK:C00001498
database_cross_reference: MetaCyc:CYTOSINE
database_cross_reference: PDBeChem:CYT
database_cross_reference: PMID:14253484
database_cross_reference: PMID:22770225
database_cross_reference: PMID:7877593
database_cross_reference: Reaxys:2637
database_cross_reference: Wikipedia:Cytosine
has exact synonym: 4-aminopyrimidin-2(1H)-one
has exact synonym: Cytosine
has exact synonym: cytosine
has_obo_namespace: chebi_ontology
has_related_synonym: 4-amino-2(1H)-pyrimidinone
has_related_synonym: 4-amino-2-hydroxypyrimidine
has_related_synonym: C
has_related_synonym: Cyt
has_related_synonym: Cytosin
has_related_synonym: Zytosin
id: CHEBI:16040
in subset: 3 STAR

halide anion
type: Class
subclass of: monoatomic monoanion
subclass of: CHEBI_79389
definition: A monoatomic monoanion resulting from the addition of an electron to any halogen atom.
imported from: chebi.owl
charge: -1
formula: X
mass: 0.0
monoisotopicmass: 0.0
smiles: [*-]
has_alternative_id: CHEBI:14384
has_alternative_id: CHEBI:5605
database_cross_reference: KEGG:C00462
has exact synonym: halide ions
has_obo_namespace: chebi_ontology
has_related_synonym: HX
has_related_synonym: Halide
has_related_synonym: a halide anion
has_related_synonym: halide anions
has_related_synonym: halide(1-)
has_related_synonym: halides
has_related_synonym: halogen anion
id: CHEBI:16042
in subset: 3 STAR

gamma-amino-beta-hydroxybutyric acid
type: Class
subclass of: gamma-amino acid
subclass of: CHEBI_35969
subclass of: Restriction
  on property: has functional parent
  some values from: butyric acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: 4-amino-3-hydroxybutanoate
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57630
definition: A gamma-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent.
imported from: chebi.owl
charge: 0
formula: C4H9NO3
inchi: InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)
inchikey: YQGDEPYYFWUPGO-UHFFFAOYSA-N
mass: 119.11920
monoisotopicmass: 119.05824
smiles: NCC(O)CC(O)=O
has_alternative_id: CHEBI:1780
has_alternative_id: CHEBI:20311
database_cross_reference: Beilstein:1721708
database_cross_reference: Beilstein:1752568
database_cross_reference: CAS:352-21-6
database_cross_reference: Drug_Central:1263
database_cross_reference: KEGG:C03678
database_cross_reference: KEGG:D00174
has exact synonym: 4-amino-3-hydroxybutanoic acid
has exact synonym: gamma-Amino-beta-hydroxybutyric acid
has_obo_namespace: chebi_ontology
has_related_synonym: 3-hydroxy-GABA
has_related_synonym: 4-Amino-3-hydroxybutanoic acid
has_related_synonym: 4-amino-3-hydroxybutyric acid
has_related_synonym: GABOB
id: CHEBI:16080
in subset: 3 STAR

ammonia
type: Class
subclass of: gas molecular entity
subclass of: azane
subclass of: CHEBI_37176
definition: An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
imported from: chebi.owl
charge: 0
formula: H3N
inchi: InChI=1S/H3N/h1H3
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-N
mass: 17.03056
monoisotopicmass: 17.02655
smiles: [H]N([H])[H]
has_alternative_id: CHEBI:13405
has_alternative_id: CHEBI:13406
has_alternative_id: CHEBI:13407
has_alternative_id: CHEBI:13771
has_alternative_id: CHEBI:22533
has_alternative_id: CHEBI:44269
has_alternative_id: CHEBI:44284
has_alternative_id: CHEBI:44404
has_alternative_id: CHEBI:7434
database_cross_reference: Beilstein:3587154
database_cross_reference: CAS:7664-41-7
database_cross_reference: Drug_Central:4625
database_cross_reference: Gmelin:79
database_cross_reference: HMDB:HMDB0000051
database_cross_reference: KEGG:C00014
database_cross_reference: KEGG:D02916
database_cross_reference: KNApSAcK:C00007267
database_cross_reference: MetaCyc:AMMONIA
database_cross_reference: MolBase:930
database_cross_reference: PDBeChem:NH3
database_cross_reference: PMID:110589
database_cross_reference: PMID:11139349
database_cross_reference: PMID:11540049
database_cross_reference: PMID:11746427
database_cross_reference: PMID:11783653
database_cross_reference: PMID:13753780
database_cross_reference: PMID:14663195
database_cross_reference: PMID:15092448
database_cross_reference: PMID:15094021
database_cross_reference: PMID:15554424
database_cross_reference: PMID:15969015
database_cross_reference: PMID:16008360
database_cross_reference: PMID:16050680
database_cross_reference: PMID:16348008
database_cross_reference: PMID:16349403
database_cross_reference: PMID:16614889
database_cross_reference: PMID:16664306
database_cross_reference: PMID:16842901
database_cross_reference: PMID:17025297
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17569513
database_cross_reference: PMID:17737668
database_cross_reference: PMID:18670398
database_cross_reference: PMID:22002069
database_cross_reference: PMID:22081570
database_cross_reference: PMID:22088435
database_cross_reference: PMID:22100291
database_cross_reference: PMID:22130175
database_cross_reference: PMID:22150211
database_cross_reference: PMID:22240068
database_cross_reference: PMID:22290316
database_cross_reference: PMID:22342082
database_cross_reference: PMID:22385337
database_cross_reference: PMID:22443779
database_cross_reference: PMID:22560242
database_cross_reference: Reaxys:3587154
database_cross_reference: Wikipedia:Ammonia
has exact synonym: AMMONIA
has exact synonym: Ammonia
has exact synonym: ammonia
has exact synonym: azane
has_obo_namespace: chebi_ontology
has_related_synonym: Ammoniak
has_related_synonym: NH3
has_related_synonym: R-717
has_related_synonym: [NH3]
has_related_synonym: ammoniac

hydrogen sulfide
type: Class
subclass of: gas molecular entity
subclass of: hydracid
subclass of: sulfur hydride
subclass of: CHEBI_37176
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: toxin
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50902
subclass of: Restriction
  on property: has role
  some values from: CHEBI_62488
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrosulfide
subclass of: Restriction
  on property: is conjugate base of
  some values from: sulfonium
definition: A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
imported from: chebi.owl
charge: 0
formula: H2S
inchi: InChI=1S/H2S/h1H2
inchikey: RWSOTUBLDIXVET-UHFFFAOYSA-N
mass: 34.08188
monoisotopicmass: 33.98772
smiles: [H]S[H]
has_alternative_id: CHEBI:13356
has_alternative_id: CHEBI:14414
has_alternative_id: CHEBI:24639
has_alternative_id: CHEBI:43058
has_alternative_id: CHEBI:45489
has_alternative_id: CHEBI:5787
database_cross_reference: Beilstein:3535004
database_cross_reference: CAS:7783-06-4
database_cross_reference: Drug_Central:4260
database_cross_reference: Gmelin:303
database_cross_reference: KEGG:C00283
database_cross_reference: KNApSAcK:C00007266
database_cross_reference: MolBase:1709
database_cross_reference: PDBeChem:H2S
database_cross_reference: PMID:11788560
database_cross_reference: PMID:14654297
database_cross_reference: PMID:15003943
database_cross_reference: PMID:15607739
database_cross_reference: PMID:16446402
database_cross_reference: PMID:18098324
database_cross_reference: PMID:18524810
database_cross_reference: PMID:18948540
database_cross_reference: PMID:19695225
database_cross_reference: PMID:22004989
database_cross_reference: PMID:22378060
database_cross_reference: PMID:22448627
database_cross_reference: PMID:22473176
database_cross_reference: PMID:22486842
database_cross_reference: PMID:22520971
database_cross_reference: PMID:22787557
database_cross_reference: UM-BBD_compID:c0239
database_cross_reference: Wikipedia:Hydrogen_sulfide
has exact synonym: Hydrogen sulfide
has exact synonym: dihydridosulfur
has exact synonym: dihydrogen(sulfide)
has exact synonym: hydrogen sulfide
has exact synonym: sulfane
has_obo_namespace: chebi_ontology
has_related_synonym: H2S
has_related_synonym: HYDROSULFURIC ACID
has_related_synonym: Hydrogen-sulfide
has_related_synonym: Schwefelwasserstoff
has_related_synonym: Sulfide
has_related_synonym: [SH2]
has_related_synonym: acide sulfhydrique
has_related_synonym: dihydrogen monosulfide
has_related_synonym: dihydrogen sulfide
has_related_synonym: hydrogen monosulfide
has_related_synonym: hydrogen sulphide
has_related_synonym: hydrogene sulfure
has_related_synonym: sulfure d'hydrogene
id: CHEBI:16136
in subset: 3 STAR

benzoate
type: Class
subclass of: benzoates
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76967
subclass of: Restriction
  on property: is conjugate base of
  some values from: benzoic acid
definition: The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1.
imported from: chebi.owl
charge: -1
formula: C7H5O2
inchi: InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)/p-1
inchikey: WPYMKLBDIGXBTP-UHFFFAOYSA-M
mass: 121.11340
monoisotopicmass: 121.02950
smiles: [O-]C(=O)c1ccccc1
has_alternative_id: CHEBI:13879
has_alternative_id: CHEBI:22717
database_cross_reference: Beilstein:1862486
database_cross_reference: CAS:766-76-7
database_cross_reference: Gmelin:2945
database_cross_reference: HMDB:HMDB0001870
database_cross_reference: KEGG:C00180
database_cross_reference: MetaCyc:BENZOATE
database_cross_reference: Reaxys:1862486
database_cross_reference: UM-BBD_compID:c0121
has exact synonym: benzoate
has_obo_namespace: chebi_ontology
has_related_synonym: Benzenecarboxylate
has_related_synonym: Benzeneformate
has_related_synonym: Benzenemethanoate
has_related_synonym: Phenylcarboxylate
has_related_synonym: Phenylformate
has_related_synonym: benzoate anion
has_related_synonym: benzoic acid, ion(1-)
id: CHEBI:16150
in subset: 3 STAR

methane
type: Class
subclass of: gas molecular entity
subclass of: alkane
subclass of: CHEBI_37176
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: fossil fuel
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76413
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methanide
definition: A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).
imported from: chebi.owl
charge: 0
formula: CH4
inchi: InChI=1S/CH4/h1H4
inchikey: VNWKTOKETHGBQD-UHFFFAOYSA-N
mass: 16.04246
monoisotopicmass: 16.03130
smiles: [H]C([H])([H])[H]
has_alternative_id: CHEBI:14585
has_alternative_id: CHEBI:25220
has_alternative_id: CHEBI:6811
database_cross_reference: Beilstein:1718732
database_cross_reference: CAS:74-82-8
database_cross_reference: Gmelin:59
database_cross_reference: HMDB:HMDB0002714
database_cross_reference: KEGG:C01438
database_cross_reference: MetaCyc:CH4
database_cross_reference: PMID:17791569
database_cross_reference: PMID:23104415
database_cross_reference: PMID:23353606
database_cross_reference: PMID:23376302
database_cross_reference: PMID:23397538
database_cross_reference: PMID:23718889
database_cross_reference: PMID:23739479
database_cross_reference: PMID:23742231
database_cross_reference: PMID:23756351
database_cross_reference: PMID:24132456
database_cross_reference: PMID:24161402
database_cross_reference: PMID:24259373
database_cross_reference: Patent:FR994032
database_cross_reference: Patent:US2583090
database_cross_reference: Reaxys:1718732
database_cross_reference: UM-BBD_compID:c0095
database_cross_reference: Wikipedia:Methane
has exact synonym: Methane
has exact synonym: methane
has exact synonym: tetrahydridocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: CH4
has_related_synonym: Methan
has_related_synonym: marsh gas
has_related_synonym: metano
has_related_synonym: methyl hydride
id: CHEBI:16183
in subset: 3 STAR

oleic acid
type: Class
subclass of: CHEBI_36021
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: CHEBI_46787
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78444
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83038
subclass of: Restriction
  on property: has parent hydride
  some values from: CHEBI_37604
subclass of: Restriction
  on property: is conjugate acid of
  some values from: oleate
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
imported from: chebi.owl
charge: 0
formula: C18H34O2
inchi: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
inchikey: ZQPPMHVWECSIRJ-KTKRTIGZSA-N
mass: 282.46140
monoisotopicmass: 282.25588
smiles: CCCCCCCC\C=C/CCCCCCCC(O)=O
has_alternative_id: CHEBI:104361
has_alternative_id: CHEBI:25664
has_alternative_id: CHEBI:44741
has_alternative_id: CHEBI:7741
database_cross_reference: Beilstein:1726542
database_cross_reference: CAS:112-80-1
database_cross_reference: DrugBank:DB04224
database_cross_reference: Drug_Central:3400
database_cross_reference: ECMDB:ECMDB21348
database_cross_reference: Gmelin:109551
database_cross_reference: Gmelin:57556
database_cross_reference: HMDB:HMDB0000207
database_cross_reference: KEGG:C00712
database_cross_reference: KEGG:D02315
database_cross_reference: KNApSAcK:C00001232
database_cross_reference: LIPID_MAPS_instance:LMFA01030002
database_cross_reference: PDBeChem:OLA
database_cross_reference: PMID:11304127
database_cross_reference: PMID:15325315
database_cross_reference: PMID:15723125
database_cross_reference: PMID:18772370
database_cross_reference: PMID:19761868
database_cross_reference: PMID:23844805
database_cross_reference: PMID:24819471
database_cross_reference: PMID:25584012
database_cross_reference: PMID:25794012
database_cross_reference: PMID:5332408
database_cross_reference: PMID:6205897
database_cross_reference: Reaxys:1726542
database_cross_reference: Wikipedia:Oleic_acid
has exact synonym: (9Z)-octadec-9-enoic acid
has exact synonym: OLEIC ACID
has exact synonym: Oleic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (9Z)-Octadecenoic acid
has_related_synonym: (Z)-Octadec-9-enoic acid
has_related_synonym: 18:1 n-9
has_related_synonym: 18:1Delta9cis
has_related_synonym: C18:1 n-9
has_related_synonym: FA 18:1
has_related_synonym: Octadec-9-enoic acid
has_related_synonym: Oelsaeure
has_related_synonym: Oleate
has_related_synonym: cis-9-octadecenoic acid
has_related_synonym: cis-Delta(9)-octadecenoic acid
has_related_synonym: cis-oleic acid
id: CHEBI:16196
in subset: 3 STAR

urea
type: Class
subclass of: monocarboxylic acid amide
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: fertilizer
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64577
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: has functional parent
  some values from: carbonic acid
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_48376
definition: A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O).
imported from: chebi.owl
charge: 0
formula: CH4N2O
inchi: InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
inchikey: XSQUKJJJFZCRTK-UHFFFAOYSA-N
mass: 60.05534
monoisotopicmass: 60.03236
smiles: NC(N)=O
has_alternative_id: CHEBI:15292
has_alternative_id: CHEBI:27218
has_alternative_id: CHEBI:46379
has_alternative_id: CHEBI:9888
database_cross_reference: Beilstein:635724
database_cross_reference: CAS:57-13-6
database_cross_reference: DrugBank:DB03904
database_cross_reference: Drug_Central:4264
database_cross_reference: ECMDB:ECMDB04172
database_cross_reference: Gmelin:1378
database_cross_reference: HMDB:HMDB0000294
database_cross_reference: KEGG:C00086
database_cross_reference: KEGG:D00023
database_cross_reference: KNApSAcK:C00007314
database_cross_reference: MetaCyc:UREA
database_cross_reference: PDBeChem:URE
database_cross_reference: PMID:18037357
database_cross_reference: PMID:22770225
database_cross_reference: PPDB:1728
database_cross_reference: Reaxys:635724
database_cross_reference: UM-BBD_compID:c0165
database_cross_reference: Wikipedia:Urea
database_cross_reference: YMDB:YMDB00003
has exact synonym: UREA
has exact synonym: Urea
has exact synonym: urea
has_obo_namespace: chebi_ontology
has_related_synonym: 1728
has_related_synonym: Carbamide
has_related_synonym: E927b
has_related_synonym: H2NC(O)NH2
has_related_synonym: Harnstoff
has_related_synonym: Karbamid
has_related_synonym: carbamide
has_related_synonym: carbonyldiamide
has_related_synonym: ur
has_related_synonym: uree
id: CHEBI:16199
in subset: 3 STAR

hydroxide
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: is conjugate base of
  some values from: water
imported from: chebi.owl
charge: -1
formula: HO
inchi: InChI=1S/H2O/h1H2/p-1
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-M
mass: 17.00734
monoisotopicmass: 17.00329
smiles: [O-][H]
has_alternative_id: CHEBI:13365
has_alternative_id: CHEBI:13419
has_alternative_id: CHEBI:44641
has_alternative_id: CHEBI:5594
database_cross_reference: CAS:14280-30-9
database_cross_reference: Gmelin:24714
database_cross_reference: KEGG:C01328
database_cross_reference: PDBeChem:OH
has exact synonym: hydridooxygenate(1-)
has exact synonym: hydroxide
has exact synonym: oxidanide
has_obo_namespace: chebi_ontology
has_related_synonym: HO-
has_related_synonym: HYDROXIDE ION
has_related_synonym: Hydroxide ion
has_related_synonym: OH(-)
has_related_synonym: OH-
id: CHEBI:16234
in subset: 3 STAR

guanine
type: Class
subclass of: 2-aminopurines
subclass of: oxopurine
subclass of: purine nucleobase
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: has parent hydride
  some values from: 9H-purine
definition: A 2-aminopurine carrying a 6-oxo substituent.
imported from: chebi.owl
charge: 0
formula: C5H5N5O
inchi: InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
inchikey: UYTPUPDQBNUYGX-UHFFFAOYSA-N
mass: 151.126
monoisotopicmass: 151.04941
smiles: C12=C(N=C(NC1=O)N)NC=N2
has_alternative_id: CHEBI:14371
has_alternative_id: CHEBI:14372
has_alternative_id: CHEBI:24443
has_alternative_id: CHEBI:42948
has_alternative_id: CHEBI:5563
database_cross_reference: Beilstein:147911
database_cross_reference: CAS:73-40-5
database_cross_reference: DrugBank:DB02377
database_cross_reference: Gmelin:431879
database_cross_reference: HMDB:HMDB0000132
database_cross_reference: KEGG:C00242
database_cross_reference: KNApSAcK:C00001501
database_cross_reference: MetaCyc:GUANINE
database_cross_reference: PDBeChem:GUN
database_cross_reference: PMID:22770225
database_cross_reference: PMID:8070089
database_cross_reference: Reaxys:147911
database_cross_reference: Wikipedia:Guanine
has exact synonym: 2-amino-1,9-dihydro-6H-purin-6-one
has exact synonym: GUANINE
has exact synonym: Guanine
has exact synonym: guanine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-6-hydroxypurine
has_related_synonym: 2-amino-6-oxopurine
has_related_synonym: G
has_related_synonym: Gua
id: CHEBI:16235
in subset: 3 STAR

ethanol
type: Class
subclass of: volatile organic compound
subclass of: primary alcohol
subclass of: ethanols
subclass of: CHEBI_50584
definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
imported from: chebi.owl
charge: 0
formula: C2H6O
inchi: InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
inchikey: LFQSCWFLJHTTHZ-UHFFFAOYSA-N
mass: 46.06844
monoisotopicmass: 46.04186
smiles: CCO
has_alternative_id: CHEBI:14222
has_alternative_id: CHEBI:23978
has_alternative_id: CHEBI:30878
has_alternative_id: CHEBI:30880
has_alternative_id: CHEBI:42377
has_alternative_id: CHEBI:44594
has_alternative_id: CHEBI:4879
database_cross_reference: Beilstein:1718733
database_cross_reference: CAS:64-17-5
database_cross_reference: DrugBank:DB00898
database_cross_reference: Drug_Central:1076
database_cross_reference: Gmelin:787
database_cross_reference: HMDB:HMDB0000108
database_cross_reference: KEGG:C00469
database_cross_reference: KEGG:D00068
database_cross_reference: KEGG:D06542
database_cross_reference: KNApSAcK:C00019560
database_cross_reference: MetaCyc:ETOH
database_cross_reference: MolBase:858
database_cross_reference: MolBase:859
database_cross_reference: PDBeChem:EOH
database_cross_reference: PMID:11046114
database_cross_reference: PMID:11090978
database_cross_reference: PMID:11198720
database_cross_reference: PMID:11200745
database_cross_reference: PMID:11262320
database_cross_reference: PMID:11303910
database_cross_reference: PMID:11333032
database_cross_reference: PMID:11505026
database_cross_reference: PMID:11590970
database_cross_reference: PMID:11728426
database_cross_reference: PMID:11750186
database_cross_reference: PMID:11754521
database_cross_reference: PMID:11810019
database_cross_reference: PMID:11826039
database_cross_reference: PMID:11981228
database_cross_reference: PMID:12824058
database_cross_reference: PMID:12829422
database_cross_reference: PMID:12888778
database_cross_reference: PMID:12946583
database_cross_reference: PMID:14674846
database_cross_reference: PMID:15019421
database_cross_reference: PMID:15239123
database_cross_reference: PMID:15285839
database_cross_reference: PMID:15464411
database_cross_reference: PMID:15465973
database_cross_reference: PMID:15749123
database_cross_reference: PMID:15900217
database_cross_reference: PMID:15902919
database_cross_reference: PMID:16084479
database_cross_reference: PMID:16133132
database_cross_reference: PMID:16352430
database_cross_reference: PMID:16390872
database_cross_reference: PMID:16737463
database_cross_reference: PMID:16891664
database_cross_reference: PMID:16934862
database_cross_reference: PMID:17043811
database_cross_reference: PMID:17190852
database_cross_reference: PMID:17663926
database_cross_reference: PMID:17687877
database_cross_reference: PMID:18095657
database_cross_reference: PMID:18249266
database_cross_reference: PMID:18320157
database_cross_reference: PMID:18347649
database_cross_reference: PMID:18408978
database_cross_reference: PMID:18411066

quercetin
type: Class
subclass of: pentahydroxyflavone
subclass of: CHEBI_52267
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000014432
subclass of: Restriction
  on property: has role
  some values from: geroprotector
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_37699
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38161
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48578
subclass of: Restriction
  on property: has role
  some values from: CHEBI_70770
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76989
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77020
subclass of: Restriction
  on property: has role
  some values from: inhibitor
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_57694
definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
definition source: Reference: PMID: 26648539
imported from: chebi.owl
charge: 0
formula: C15H10O7
inchi: InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
inchikey: REFJWTPEDVJJIY-UHFFFAOYSA-N
mass: 302.238
monoisotopicmass: 302.04265
has_alternative_id: CHEBI:11704
has_alternative_id: CHEBI:14991
has_alternative_id: CHEBI:26472
has_alternative_id: CHEBI:45280
has_alternative_id: CHEBI:8696
database_cross_reference: Beilstein:317313
database_cross_reference: CAS:117-39-5
database_cross_reference: DrugBank:DB04216
database_cross_reference: Drug_Central:3514
database_cross_reference: FooDB:FDB011904
database_cross_reference: Gmelin:579210
database_cross_reference: HMDB:HMDB0005794
database_cross_reference: KEGG:C00389
database_cross_reference: KNApSAcK:C00004631
database_cross_reference: LINCS:LSM-4199
database_cross_reference: LIPID_MAPS_instance:LMPK12110004
database_cross_reference: MetaCyc:CPD-520
database_cross_reference: PDBeChem:QUE
database_cross_reference: PMID:16226777
database_cross_reference: PMID:17015250
database_cross_reference: PMID:17135030
database_cross_reference: PMID:17426744
database_cross_reference: PMID:18096136
database_cross_reference: PMID:18484521
database_cross_reference: PMID:18549926
database_cross_reference: PMID:18564899
database_cross_reference: PMID:18579649
database_cross_reference: PMID:18785622
database_cross_reference: PMID:19043800
database_cross_reference: PMID:19461927
database_cross_reference: PMID:22920589
database_cross_reference: PMID:23342112
database_cross_reference: PMID:23359794
database_cross_reference: PMID:27565033
database_cross_reference: PMID:27589790
database_cross_reference: PMID:27591927
database_cross_reference: PMID:27704720
database_cross_reference: Patent:KR20120121684
database_cross_reference: Patent:US2013012577
database_cross_reference: Reaxys:317313
database_cross_reference: Wikipedia:Quercetin
has exact synonym: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
has exact synonym: Quercetin
has_obo_namespace: chebi_ontology
has_related_synonym: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
has_related_synonym: 3,3',4',5,7-pentahydroxyflavone
has_related_synonym: 3,5,7,3',4'-PENTAHYDROXYFLAVONE
has_related_synonym: 3,5,7,3',4'-Pentahydroxyflavone
has_related_synonym: sophoretin
has_related_synonym: xanthaurine
id: CHEBI:16243
in subset: 3 STAR

D-proline
type: Class
subclass of: D-alpha-amino acid
subclass of: proline
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-prolinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-prolinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-proline
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57726
definition: The D-enantiomer of proline.
imported from: chebi.owl
charge: 0
formula: C5H9NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
inchikey: ONIBWKKTOPOVIA-SCSAIBSYSA-N
mass: 115.13050
monoisotopicmass: 115.06333
smiles: OC(=O)[C@H]1CCCN1
has_alternative_id: CHEBI:13008
has_alternative_id: CHEBI:21070
has_alternative_id: CHEBI:42012
has_alternative_id: CHEBI:42129
has_alternative_id: CHEBI:42213
has_alternative_id: CHEBI:4226
has_alternative_id: CHEBI:45156
database_cross_reference: Beilstein:80811
database_cross_reference: CAS:344-25-2
database_cross_reference: DrugBank:DB02853
database_cross_reference: Gmelin:833984
database_cross_reference: HMDB:HMDB0003411
database_cross_reference: KEGG:C00763
database_cross_reference: MetaCyc:D-PROLINE
database_cross_reference: PDBeChem:DPR
database_cross_reference: PMID:19023642
database_cross_reference: PMID:20023020
database_cross_reference: PMID:20959625
database_cross_reference: PMID:21374575
database_cross_reference: PMID:21563681
database_cross_reference: PMID:22475019
database_cross_reference: PMID:22479580
database_cross_reference: Reaxys:80811
database_cross_reference: Wikipedia:D-proline
has exact synonym: D-PROLINE
has exact synonym: D-Proline
has exact synonym: D-proline
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-pyrrolidine-2-carboxylic acid
has_related_synonym: (R)-2-Carboxypyrrolidine
has_related_synonym: (R)-pyrrolidine-2-carboxylic acid
has_related_synonym: D-Prolin
has_related_synonym: DPR
id: CHEBI:16313
in subset: 3 STAR

(R)-carnitine
type: Class
subclass of: carnitine
subclass of: Restriction
  on property: has role
  some values from: water-soluble vitamin (role)
subclass of: Restriction
  on property: has role
  some values from: antilipemic drug
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_66980
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_39547
subclass of: Restriction
  on property: is enantiomer of
  some values from: (S)-carnitine
definition: The (R)-enantiomer of carnitine.
imported from: chebi.owl
charge: 0
formula: C7H15NO3
inchi: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
inchikey: PHIQHXFUZVPYII-ZCFIWIBFSA-N
mass: 161.19894
monoisotopicmass: 161.10519
smiles: C[N+](C)(C)C[C@H](O)CC([O-])=O
has_alternative_id: CHEBI:13091
has_alternative_id: CHEBI:21256
has_alternative_id: CHEBI:6202
database_cross_reference: Beilstein:4292315
database_cross_reference: Beilstein:5732837
database_cross_reference: CAS:541-15-1
database_cross_reference: DrugBank:DB00583
database_cross_reference: Drug_Central:513
database_cross_reference: Gmelin:1782973
database_cross_reference: HMDB:HMDB0000062
database_cross_reference: KEGG:C00318
database_cross_reference: KEGG:D02176
database_cross_reference: MetaCyc:CARNITINE
database_cross_reference: PDBeChem:152
has exact synonym: (3R)-3-hydroxy-4-(trimethylammonio)butanoate
has exact synonym: (R)-Carnitine
has exact synonym: (R)-carnitine
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-Carnitine
has_related_synonym: (-)-L-Carnitine
has_related_synonym: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt
has_related_synonym: Carnicor
has_related_synonym: Carnitene
has_related_synonym: Carnitine
has_related_synonym: Carnitor
has_related_synonym: L-Carnitine
has_related_synonym: Levocarnitine
has_related_synonym: Vitamin BT
id: CHEBI:16347
in subset: 3 STAR

D-cysteine
type: Class
subclass of: cysteine
subclass of: D-alpha-amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-cysteinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-cysteine
subclass of: Restriction
  on property: is tautomer of
  some values from: D-cysteine zwitterion
definition: An optically active form of cysteine having D-configuration.
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1
inchikey: XUJNEKJLAYXESH-UWTATZPHSA-N
mass: 121.15922
monoisotopicmass: 121.01975
smiles: N[C@H](CS)C(O)=O
has_alternative_id: CHEBI:12919
has_alternative_id: CHEBI:20921
has_alternative_id: CHEBI:4111
has_alternative_id: CHEBI:41887
database_cross_reference: Beilstein:1721407
database_cross_reference: CAS:921-01-7
database_cross_reference: DrugBank:DB03201
database_cross_reference: ECMDB:ECMDB03417
database_cross_reference: Gmelin:363236
database_cross_reference: HMDB:HMDB0003417
database_cross_reference: KEGG:C00793
database_cross_reference: KNApSAcK:C00007323
database_cross_reference: PDBeChem:DCY
database_cross_reference: PMID:13761469
database_cross_reference: PMID:23340406
database_cross_reference: PMID:24800864
database_cross_reference: Reaxys:1721407
database_cross_reference: YMDB:YMDB00913
has exact synonym: D-CYSTEINE
has exact synonym: D-Cysteine
has exact synonym: D-cysteine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-mercaptopropanoic acid
has_related_synonym: (2S)-2-amino-3-sulfanylpropanoic acid
has_related_synonym: (S)-2-amino-3-mercaptopropanoic acid
has_related_synonym: D-Amino-3-mercaptopropionic acid
has_related_synonym: D-Cystein
has_related_synonym: D-Zystein
has_related_synonym: DCY
id: CHEBI:16375
in subset: 3 STAR

organic sulfide
type: Class
subclass of: sulfide
subclass of: organosulfur compound
definition: Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers.
imported from: chebi.owl
charge: 0
formula: SR2
mass: 32.066
monoisotopicmass: 31.97207
has_alternative_id: CHEBI:13694
has_alternative_id: CHEBI:26960
has_alternative_id: CHEBI:9340
database_cross_reference: KEGG:C00297
has exact synonym: sulfides
has_obo_namespace: chebi_ontology
has_related_synonym: RSR
has_related_synonym: Sulfide
has_related_synonym: Thioether
has_related_synonym: organic sulfides
has_related_synonym: thioethers
id: CHEBI:16385
in subset: 3 STAR

D-threonine
type: Class
subclass of: D-alpha-amino acid
subclass of: threonine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-threoninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-threoninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-threonine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57757
definition: An optically active form of threonine having D-configuration.
imported from: chebi.owl
charge: 0
formula: C4H9NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m0/s1
inchikey: AYFVYJQAPQTCCC-STHAYSLISA-N
mass: 119.11920
monoisotopicmass: 119.05824
smiles: C[C@H](O)[C@@H](N)C(O)=O
has_alternative_id: CHEBI:13027
has_alternative_id: CHEBI:21107
has_alternative_id: CHEBI:42146
has_alternative_id: CHEBI:42196
has_alternative_id: CHEBI:42224
has_alternative_id: CHEBI:4254
has_alternative_id: CHEBI:45935
has_alternative_id: CHEBI:45990
database_cross_reference: Beilstein:1721643
database_cross_reference: Beilstein:4656043
database_cross_reference: CAS:632-20-2
database_cross_reference: DrugBank:DB03700
database_cross_reference: ECMDB:ECMDB21519
database_cross_reference: Gmelin:874136
database_cross_reference: HMDB:HMDB0013775
database_cross_reference: KEGG:C00820
database_cross_reference: PDBeChem:DTH
database_cross_reference: PMID:15375647
database_cross_reference: PMID:17081141
database_cross_reference: PMID:22176976
database_cross_reference: Reaxys:1721643
database_cross_reference: YMDB:YMDB00802
has exact synonym: D-THREONINE
has exact synonym: D-Threonine
has exact synonym: D-threonine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R,3S)-2-amino-3-hydroxybutanoic acid
has_related_synonym: D-2-Amino-3-hydroxybutyric acid
has_related_synonym: D-Threonin
has_related_synonym: DTH
id: CHEBI:16398
in subset: 3 STAR

L-valine
type: Class
subclass of: L-alpha-amino acid
subclass of: pyruvate family amino acid
subclass of: valine
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-valinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-valinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-valine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57762
definition: The L-enantiomer of valine.
imported from: chebi.owl
charge: 0
formula: C5H11NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
inchikey: KZSNJWFQEVHDMF-BYPYZUCNSA-N
mass: 117.14638
monoisotopicmass: 117.07898
smiles: CC(C)[C@H](N)C(O)=O
has_alternative_id: CHEBI:13186
has_alternative_id: CHEBI:21417
has_alternative_id: CHEBI:46282
has_alternative_id: CHEBI:46376
has_alternative_id: CHEBI:46418
has_alternative_id: CHEBI:46484
has_alternative_id: CHEBI:6321
database_cross_reference: Beilstein:1721136
database_cross_reference: CAS:72-18-4
database_cross_reference: DrugBank:DB00161
database_cross_reference: Drug_Central:4128
database_cross_reference: Gmelin:2827
database_cross_reference: HMDB:HMDB0000883
database_cross_reference: KEGG:C00183
database_cross_reference: KEGG:D00039
database_cross_reference: KNApSAcK:C00001398
database_cross_reference: MetaCyc:VAL
database_cross_reference: PDBeChem:VAL
database_cross_reference: PMID:14608070
database_cross_reference: PMID:17670823
database_cross_reference: PMID:21706252
database_cross_reference: PMID:22138982
database_cross_reference: PMID:22287678
database_cross_reference: PMID:22585822
database_cross_reference: Reaxys:1721136
database_cross_reference: Wikipedia:L-valine
has exact synonym: L-Valine
has exact synonym: L-valine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-methylbutanoic acid
has_related_synonym: (S)-valine
has_related_synonym: 2-Amino-3-methylbutyric acid
has_related_synonym: L-(+)-alpha-Aminoisovaleric acid
has_related_synonym: L-Valin
has_related_synonym: L-alpha-Amino-beta-methylbutyric acid
has_related_synonym: V
has_related_synonym: VALINE
has_related_synonym: Val
id: CHEBI:16414
in subset: 3 STAR

alanine
type: Class
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: has functional parent
  some values from: propionic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alaninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: alaninium
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_66916
definition: An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
imported from: chebi.owl
charge: 0
formula: C3H7NO2
inchi: InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)
inchikey: QNAYBMKLOCPYGJ-UHFFFAOYSA-N
mass: 89.09322
monoisotopicmass: 89.04768
smiles: CC(N)C(O)=O
has_alternative_id: CHEBI:13748
has_alternative_id: CHEBI:22277
has_alternative_id: CHEBI:2539
database_cross_reference: Beilstein:635807
database_cross_reference: CAS:302-72-7
database_cross_reference: Drug_Central:4306
database_cross_reference: Gmelin:2449
database_cross_reference: KEGG:C01401
database_cross_reference: PMID:17439666
database_cross_reference: PMID:22264337
database_cross_reference: Reaxys:635807
database_cross_reference: Wikipedia:Alanine
has exact synonym: 2-aminopropanoic acid
has exact synonym: Alanine
has exact synonym: alanine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Aminopropanoic acid
has_related_synonym: 2-Aminopropionic acid
has_related_synonym: A
has_related_synonym: ALA
has_related_synonym: Alanin
has_related_synonym: alanina
id: CHEBI:16449
in subset: 3 STAR

D-serine
type: Class
subclass of: D-alpha-amino acid
subclass of: serine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64571
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-serinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-serinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-serine
subclass of: Restriction
  on property: is tautomer of
  some values from: D-serine zwitterion
definition: The R-enantiomer of serine.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
inchikey: MTCFGRXMJLQNBG-UWTATZPHSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: N[C@H](CO)C(O)=O
has_alternative_id: CHEBI:13019
has_alternative_id: CHEBI:143888
has_alternative_id: CHEBI:21090
has_alternative_id: CHEBI:42262
has_alternative_id: CHEBI:4245
database_cross_reference: Beilstein:1721403
database_cross_reference: CAS:312-84-5
database_cross_reference: DrugBank:DB03929
database_cross_reference: ECMDB:ECMDB03406
database_cross_reference: Gmelin:1041392
database_cross_reference: HMDB:HMDB0003406
database_cross_reference: KEGG:C00740
database_cross_reference: MetaCyc:D-SERINE
database_cross_reference: PDBeChem:DSN
database_cross_reference: PMID:11864625
database_cross_reference: PMID:12850593
database_cross_reference: PMID:19212759
database_cross_reference: PMID:19217074
database_cross_reference: PMID:21295046
database_cross_reference: PMID:21914633
database_cross_reference: PMID:21956571
database_cross_reference: PMID:22117694
database_cross_reference: PMID:22128843
database_cross_reference: PMID:22266400
database_cross_reference: PMID:22280157
database_cross_reference: PMID:22362148
database_cross_reference: PMID:22369458
database_cross_reference: PMID:22445805
database_cross_reference: PMID:22465696
database_cross_reference: PMID:22486999
database_cross_reference: Reaxys:1721403
database_cross_reference: YMDB:YMDB00284
has exact synonym: D-SERINE
has exact synonym: D-Serine
has exact synonym: D-serine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-hydroxypropanoic acid
has_related_synonym: (R)-2-Amino-3-hydroxy-propionic acid
has_related_synonym: (R)-2-amino-3-hydroxypropanoic acid
has_related_synonym: D-Serin
has_related_synonym: DSN
id: CHEBI:16523
in subset: 3 STAR

L-methionine
type: Class
subclass of: L-alpha-amino acid
subclass of: methionine
subclass of: aspartate family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_74529
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-methioninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-methioninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-methionine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57844
definition: The L-enantiomer of methionine.
imported from: chebi.owl
charge: 0
formula: C5H11NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
inchikey: FFEARJCKVFRZRR-BYPYZUCNSA-N
mass: 149.21238
monoisotopicmass: 149.05105
smiles: CSCC[C@H](N)C(O)=O
has_alternative_id: CHEBI:13141
has_alternative_id: CHEBI:21360
has_alternative_id: CHEBI:43990
has_alternative_id: CHEBI:6271
database_cross_reference: CAS:63-68-3
database_cross_reference: DrugBank:DB00134
database_cross_reference: Drug_Central:3347
database_cross_reference: ECMDB:ECMDB00696
database_cross_reference: Gmelin:26935
database_cross_reference: HMDB:HMDB0000696
database_cross_reference: KEGG:C00073
database_cross_reference: KEGG:D00019
database_cross_reference: KNApSAcK:C00001379
database_cross_reference: MetaCyc:MET
database_cross_reference: PDBeChem:MET_LFOH
database_cross_reference: PMID:16575097
database_cross_reference: PMID:21683740
database_cross_reference: PMID:21946918
database_cross_reference: PMID:22200379
database_cross_reference: PMID:22370952
database_cross_reference: PMID:22448874
database_cross_reference: PMID:22517898
database_cross_reference: PMID:24126240
database_cross_reference: PMID:24939187
database_cross_reference: PMID:5764336
database_cross_reference: Reaxys:1722294
database_cross_reference: YMDB:YMDB00318
has exact synonym: L-Methionine
has exact synonym: L-methionine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-4-(methylsulfanyl)butanoic acid
has_related_synonym: (S)-2-amino-4-(methylthio)butanoic acid
has_related_synonym: (S)-2-amino-4-(methylthio)butyric acid
has_related_synonym: (S)-methionine
has_related_synonym: L-(-)-methionine
has_related_synonym: L-Methionin
has_related_synonym: L-alpha-amino-gamma-methylmercaptobutyric acid
has_related_synonym: M
has_related_synonym: METHIONINE
has_related_synonym: Met
has_related_synonym: Methionine
id: CHEBI:16643
in subset: 3 STAR

carbohydrate
type: Class
subclass of: CHEBI_78616
definition: Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
imported from: chebi.owl
has_alternative_id: CHEBI:15131
has_alternative_id: CHEBI:23008
has_alternative_id: CHEBI:9318
database_cross_reference: Wikipedia:Carbohydrate
has exact synonym: carbohydrate
has exact synonym: carbohydrates
has_obo_namespace: chebi_ontology
has_related_synonym: Kohlenhydrat
has_related_synonym: Kohlenhydrate
has_related_synonym: a carbohydrate
has_related_synonym: carbohidrato
has_related_synonym: carbohidratos
has_related_synonym: glucide
has_related_synonym: glucides
has_related_synonym: glucido
has_related_synonym: glucidos
has_related_synonym: hydrates de carbone
has_related_synonym: saccharide
has_related_synonym: saccharides
has_related_synonym: saccharidum
id: CHEBI:16646
in subset: 3 STAR

peptide
type: Class
subclass of: macromolecule
subclass of: CHEBI_37622
subclass of: CHEBI_50047
subclass of: Restriction
  on property: has part
  some values from: amino-acid residue
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_60466
editor preferred label: peptide
definition: Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid.
definition: Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
imported from: chebi.owl
imported from: dron.owl
imported from: obi.owl
charge: 0
formula: (C2H2NOR)nC2H3NOR
has_alternative_id: CHEBI:14753
has_alternative_id: CHEBI:25906
has_alternative_id: CHEBI:7990
database_cross_reference: KEGG COMPOUND:C00012
database_cross_reference: KEGG:C00012
has exact synonym: Peptide
has exact synonym: peptides
has_obo_namespace: chebi_ontology
has_related_synonym: C2H4NO2R(C2H2NOR)n
has_related_synonym: Peptid
has_related_synonym: peptido
has_related_synonym: peptidos
id: CHEBI:16670
in subset: 3 STAR

secondary fatty alcohol
type: Class
subclass of: fatty alcohol
definition: A fatty alcohol consisting of a chain of 3 to greater than 27 carbon atoms in which a hydroxy group is attached to a saturated carbon atom different from the terminal carbons. Secondary fatty alcohols may be saturated or unsaturated and may be branched or unbranched.
imported from: chebi.owl
charge: 0
formula: CH2OR2
mass: 30.026
monoisotopicmass: 30.01056
smiles: *C(O)*
has_obo_namespace: chebi_ontology
has_related_synonym: a secondary fatty alcohol
id: CHEBI:167095
in subset: 2 STAR

N-(fatty acyl)-ethanolamine
type: Class
subclass of: fatty amide
subclass of: CHEBI_52640
definition: an N-acyl-ethanolamine where the acyl group is a fatty acyl chain with composition not specified, major species at pH 7.3.
imported from: chebi.owl
charge: 0
formula: C3H6NO2R
mass: 88.085
monoisotopicmass: 88.03985
smiles: N(C(*)=O)(CCO)[H]
has_obo_namespace: chebi_ontology
has_related_synonym: an N-(fatty acyl)-ethanolamine
id: CHEBI:167098
in subset: 2 STAR

benzene
type: Class
subclass of: volatile organic compound
subclass of: benzenes
subclass of: aromatic annulene
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48355
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50903
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78298
definition: A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system.
imported from: chebi.owl
charge: 0
formula: C6H6
inchi: InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
inchikey: UHOVQNZJYSORNB-UHFFFAOYSA-N
mass: 78.11184
monoisotopicmass: 78.04695
smiles: c1ccccc1
has_alternative_id: CHEBI:13876
has_alternative_id: CHEBI:22703
has_alternative_id: CHEBI:3025
has_alternative_id: CHEBI:41187
database_cross_reference: Beilstein:969212
database_cross_reference: CAS:71-43-2
database_cross_reference: Gmelin:1671
database_cross_reference: HMDB:HMDB0001505
database_cross_reference: KEGG:C01407
database_cross_reference: PDBeChem:BNZ
database_cross_reference: PMID:11684179
database_cross_reference: PMID:11993966
database_cross_reference: PMID:12857942
database_cross_reference: PMID:14677922
database_cross_reference: PMID:15468289
database_cross_reference: PMID:15935818
database_cross_reference: PMID:16161967
database_cross_reference: PMID:17373369
database_cross_reference: PMID:18072742
database_cross_reference: PMID:18407866
database_cross_reference: PMID:18409691
database_cross_reference: PMID:18836923
database_cross_reference: PMID:19228219
database_cross_reference: PMID:21325737
database_cross_reference: PMID:23088855
database_cross_reference: PMID:23222815
database_cross_reference: PMID:23534829
database_cross_reference: PMID:6353911
database_cross_reference: PMID:8124204
database_cross_reference: Reaxys:969212
database_cross_reference: UM-BBD_compID:c0142
database_cross_reference: Wikipedia:Benzene
has exact synonym: BENZENE
has exact synonym: Benzene
has exact synonym: benzene
has_obo_namespace: chebi_ontology
has_related_synonym: Benzen
has_related_synonym: Benzine
has_related_synonym: Benzol
has_related_synonym: Bicarburet of hydrogen
has_related_synonym: Coal naphtha
has_related_synonym: Mineral naphtha
has_related_synonym: Phene
has_related_synonym: Pyrobenzol
has_related_synonym: Pyrobenzole
has_related_synonym: [6]annulene
has_related_synonym: benzole
has_related_synonym: cyclohexatriene
has_related_synonym: phenyl hydride
id: CHEBI:16716
in subset: 3 STAR

piscicide
type: Class
subclass of: pesticide
definition: A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water.
imported from: chebi.owl
database_cross_reference: Wikipedia:Piscicide
has_obo_namespace: chebi_ontology
has_related_synonym: piscicides
id: CHEBI:167183
in subset: 3 STAR

D-alpha-amino acid
type: Class
subclass of: CHEBI_83925
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_60895
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_59871
imported from: chebi.owl
charge: 0
formula: C2H4NO2R
mass: 74.05870
monoisotopicmass: 74.02420
smiles: N[C@H]([*])C(O)=O
has_alternative_id: CHEBI:12909
has_alternative_id: CHEBI:13625
has_alternative_id: CHEBI:20906
has_alternative_id: CHEBI:4097
database_cross_reference: KEGG:C00405
has exact synonym: D-alpha-amino acid
has exact synonym: D-alpha-amino acids
has_obo_namespace: chebi_ontology
has_related_synonym: D-Amino acid
has_related_synonym: D-alpha-amino acids
id: CHEBI:16733
in subset: 3 STAR

glycan
type: Class
subclass of: CHEBI_78616
definition: Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: glycans
id: CHEBI:167559
in subset: 3 STAR

methionine
type: Class
subclass of: sulfur-containing amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: has functional parent
  some values from: butyric acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methioninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: methioninium
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_64558
definition: A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.
imported from: chebi.owl
charge: 0
formula: C5H11NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
inchikey: FFEARJCKVFRZRR-UHFFFAOYSA-N
mass: 149.21238
monoisotopicmass: 149.05105
smiles: CSCCC(N)C(O)=O
has_alternative_id: CHEBI:14590
has_alternative_id: CHEBI:25229
has_alternative_id: CHEBI:6829
database_cross_reference: Beilstein:636185
database_cross_reference: CAS:59-51-8
database_cross_reference: Gmelin:3117
database_cross_reference: KEGG:C01733
database_cross_reference: KEGG:D04983
database_cross_reference: PMID:16702333
database_cross_reference: PMID:22264337
database_cross_reference: PMID:2543976
database_cross_reference: Reaxys:636185
database_cross_reference: UM-BBD_compID:c0094
database_cross_reference: Wikipedia:Methionine
has exact synonym: Methionine
has exact synonym: methionine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-4-(methylthio)butyric acid
has_related_synonym: 2-amino-4-(methylsulfanyl)butanoic acid
has_related_synonym: 2-amino-4-(methylthio)butanoic acid
has_related_synonym: DL-Methionine
has_related_synonym: Hmet
has_related_synonym: M
has_related_synonym: Met
has_related_synonym: Methionin
has_related_synonym: Racemethionine
has_related_synonym: alpha-amino-gamma-methylmercaptobutyric acid
has_related_synonym: metionina
id: CHEBI:16811
in subset: 3 STAR

mycophenolic acid
type: Class
subclass of: monocarboxylic acid
subclass of: phenols
subclass of: CHEBI_37581
subclass of: CHEBI_38831
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000009022
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P12268
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: mycotoxin
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: immunosuppressive agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_53746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76964
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78298
subclass of: Restriction
  on property: has role
  some values from: inhibitor
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_38355
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_62932
definition: A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.
definition source: PMID: 27344959
definition source: Reference: PMID: 5799033
definition source: https://www.drugbank.ca/drugs/DB01024
imported from: chebi.owl
charge: 0
formula: C17H20O6
inchi: InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
inchikey: HPNSFSBZBAHARI-RUDMXATFSA-N
mass: 320.33710
monoisotopicmass: 320.12599
smiles: COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(O)=O
has_alternative_id: CHEBI:43973
database_cross_reference: Beilstein:318158
database_cross_reference: CAS:24280-93-1
database_cross_reference: DrugBank:DB01024
database_cross_reference: Drug_Central:1860
database_cross_reference: KEGG:D05096
database_cross_reference: PDBeChem:MOA
database_cross_reference: PMID:11272311
database_cross_reference: PMID:15470161
database_cross_reference: PMID:16629948
database_cross_reference: PMID:16640327
database_cross_reference: PMID:17482154
database_cross_reference: PMID:17498396
database_cross_reference: PMID:18194117
database_cross_reference: PMID:18611107
database_cross_reference: PMID:18996104
database_cross_reference: PMID:19689217
database_cross_reference: Patent:US4753935
database_cross_reference: Reaxys:318158
database_cross_reference: Wikipedia:Mycophenolic_acid
has exact synonym: (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
has_related_synonym: Micofenolico acido
has_related_synonym: Mycophenolate
has_related_synonym: Mycophenolsaeure
has_related_synonym: acide mycophenolique
has_related_synonym: acido micofenolico
has_related_synonym: acidum mycophenolicum
has_related_synonym: mycophenolic acid
id: CHEBI:168396
in subset: 3 STAR

Ganolucidic acid A
type: Class
subclass of: CHEBI_36615
imported from: chebi.owl
charge: 0
formula: C30H44O6
inchi: InChI=1S/C30H44O6/c1-16(12-18(31)13-17(2)26(35)36)20-14-24(34)30(7)19-8-9-22-27(3,4)23(33)10-11-28(22,5)25(19)21(32)15-29(20,30)6/h16-17,20,22,24,34H,8-15H2,1-7H3,(H,35,36)/t16-,17-,20-,22+,24+,28+,29-,30-/m1/s1
inchikey: XRXBNTYHQXKSAO-WRRQQOFWSA-N
mass: 500.676
monoisotopicmass: 500.31379
database_cross_reference: CAS:98665-21-5
database_cross_reference: Chemspider:417367
has exact synonym: (2R,6R)-6-[(5R,10S,13R,14R,15S,17R)-15-hydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
has_obo_namespace: chebi_ontology
id: CHEBI:168397
in subset: 2 STAR

D-lysine
type: Class
subclass of: D-alpha-amino acid
subclass of: lysine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76946
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-lysinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-lysinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysine
definition: The D-enantiomer of the alpha-amino acid lysine.
imported from: chebi.owl
charge: 0
formula: C6H14N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m1/s1
inchikey: KDXKERNSBIXSRK-RXMQYKEDSA-N
mass: 146.18764
monoisotopicmass: 146.10553
smiles: NCCCC[C@@H](N)C(O)=O
has_alternative_id: CHEBI:12994
has_alternative_id: CHEBI:21046
has_alternative_id: CHEBI:4203
has_alternative_id: CHEBI:42062
database_cross_reference: Beilstein:1722530
database_cross_reference: CAS:923-27-3
database_cross_reference: DrugBank:DB03252
database_cross_reference: Gmelin:1926332
database_cross_reference: HMDB:HMDB0003405
database_cross_reference: KEGG:C00739
database_cross_reference: MetaCyc:CPD-219
database_cross_reference: PDBeChem:DLY
database_cross_reference: PMID:10571145
database_cross_reference: PMID:10930630
database_cross_reference: PMID:125972
database_cross_reference: PMID:15561717
database_cross_reference: PMID:15914930
database_cross_reference: PMID:16595662
database_cross_reference: PMID:17259313
database_cross_reference: PMID:22569959
database_cross_reference: PMID:23023754
database_cross_reference: PMID:23090865
database_cross_reference: PMID:2435906
database_cross_reference: PMID:2493343
database_cross_reference: PMID:2503300
database_cross_reference: PMID:2510957
database_cross_reference: PMID:4359655
database_cross_reference: PMID:4391118
database_cross_reference: PMID:4710063
database_cross_reference: PMID:5128165
database_cross_reference: PMID:6448848
database_cross_reference: PMID:7563967
database_cross_reference: PMID:77880
database_cross_reference: PMID:8063049
database_cross_reference: PMID:8234494
database_cross_reference: PMID:8405749
database_cross_reference: PMID:9163947
database_cross_reference: PMID:9430472
database_cross_reference: Reaxys:1722530
has exact synonym: (2R)-2,6-diaminohexanoic acid
has exact synonym: D-LYSINE
has exact synonym: D-Lysine
has exact synonym: D-lysine
has_obo_namespace: chebi_ontology
has_related_synonym: (R)-2,6-diaminohexanoic acid
has_related_synonym: D-2,6-Diaminohexanoic acid
has_related_synonym: D-Lysin
has_related_synonym: DLY
id: CHEBI:16855
in subset: 3 STAR

L-threonine
type: Class
subclass of: L-alpha-amino acid
subclass of: aspartate family amino acid
subclass of: threonine
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-threoninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-threoninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-threonine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57926
definition: An optically active form of threonine having L-configuration.
imported from: chebi.owl
charge: 0
formula: C4H9NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
inchikey: AYFVYJQAPQTCCC-GBXIJSLDSA-N
mass: 119.11920
monoisotopicmass: 119.05824
smiles: C[C@@H](O)[C@H](N)C(O)=O
has_alternative_id: CHEBI:13175
has_alternative_id: CHEBI:21403
has_alternative_id: CHEBI:42083
has_alternative_id: CHEBI:45843
has_alternative_id: CHEBI:45983
has_alternative_id: CHEBI:6308
database_cross_reference: Beilstein:1721646
database_cross_reference: CAS:72-19-5
database_cross_reference: DrugBank:DB00156
database_cross_reference: Drug_Central:4254
database_cross_reference: ECMDB:ECMDB00167
database_cross_reference: Gmelin:82510
database_cross_reference: HMDB:HMDB0000167
database_cross_reference: KEGG:C00188
database_cross_reference: KEGG:D00041
database_cross_reference: KNApSAcK:C00001394
database_cross_reference: PDBeChem:THR
database_cross_reference: PMID:11964235
database_cross_reference: PMID:12523390
database_cross_reference: PMID:16659349
database_cross_reference: PMID:17379183
database_cross_reference: PMID:22289691
database_cross_reference: PMID:22342587
database_cross_reference: PMID:22513921
database_cross_reference: PMID:22770225
database_cross_reference: PMID:24671569
database_cross_reference: Reaxys:1721646
database_cross_reference: UM-BBD_compID:c0413
database_cross_reference: Wikipedia:Threonine
database_cross_reference: YMDB:YMDB00214
has exact synonym: L-Threonine
has exact synonym: L-threonine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-threonine
has_related_synonym: (2S,3R)-(-)-Threonine
has_related_synonym: (2S,3R)-2-amino-3-hydroxybutanoic acid
has_related_synonym: 2-Amino-3-hydroxybutyric acid
has_related_synonym: L-(-)-Threonine
has_related_synonym: L-2-Amino-3-hydroxybutyric acid
has_related_synonym: L-Threonin
has_related_synonym: L-alpha-amino-beta-hydroxybutyric acid
has_related_synonym: T
has_related_synonym: THREONINE
has_related_synonym: Thr
id: CHEBI:16857
in subset: 3 STAR

D-methionine
type: Class
subclass of: D-alpha-amino acid
subclass of: methionine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-methioninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-methioninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-methionine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57932
definition: An optically active form of methionine having D-configuration.
imported from: chebi.owl
charge: 0
formula: C5H11NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
inchikey: FFEARJCKVFRZRR-SCSAIBSYSA-N
mass: 149.21238
monoisotopicmass: 149.05105
smiles: CSCC[C@@H](N)C(O)=O
has_alternative_id: CHEBI:13005
has_alternative_id: CHEBI:21065
has_alternative_id: CHEBI:4215
has_alternative_id: CHEBI:44071
database_cross_reference: Beilstein:1722293
database_cross_reference: CAS:348-67-4
database_cross_reference: DrugBank:DB02893
database_cross_reference: ECMDB:ECMDB21203
database_cross_reference: Gmelin:26934
database_cross_reference: KEGG:C00855
database_cross_reference: MetaCyc:CPD-218
database_cross_reference: PDBeChem:MED
database_cross_reference: PMID:15375647
database_cross_reference: PMID:20431016
database_cross_reference: PMID:20872028
database_cross_reference: PMID:21480759
database_cross_reference: PMID:21750343
database_cross_reference: PMID:21924333
database_cross_reference: PMID:22192214
database_cross_reference: PMID:22304623
database_cross_reference: PMID:318639
database_cross_reference: Reaxys:1722293
database_cross_reference: YMDB:YMDB00816
has exact synonym: D-METHIONINE
has exact synonym: D-Methionine
has exact synonym: D-methionine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-4-(methylsulfanyl)butanoic acid
has_related_synonym: (R)-2-amino-4-(methylthio)butanoic acid
has_related_synonym: (R)-methionine
has_related_synonym: D-2-Amino-4-(methylthio)butyric acid
has_related_synonym: D-Methionin
has_related_synonym: MED
id: CHEBI:16867
in subset: 3 STAR

salicylic acid
type: Class
subclass of: monohydroxybenzoic acid
subclass of: Restriction
  on property: has role
  some values from: antiinfective agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35718
subclass of: Restriction
  on property: has role
  some values from: CHEBI_37848
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50176
subclass of: Restriction
  on property: has role
  some values from: CHEBI_73181
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: salicylate
definition: A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves.
imported from: chebi.owl
charge: 0
formula: C7H6O3
inchi: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
inchikey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
mass: 138.12070
monoisotopicmass: 138.03169
smiles: OC(=O)c1ccccc1O
has_alternative_id: CHEBI:26597
has_alternative_id: CHEBI:45521
has_alternative_id: CHEBI:9006
database_cross_reference: Beilstein:774890
database_cross_reference: CAS:69-72-7
database_cross_reference: DrugBank:DB00936
database_cross_reference: Drug_Central:2416
database_cross_reference: Gmelin:3418
database_cross_reference: HMDB:HMDB0001895
database_cross_reference: KEGG:C00805
database_cross_reference: KEGG:D00097
database_cross_reference: KNApSAcK:C00000206
database_cross_reference: LINCS:LSM-4763
database_cross_reference: MetaCyc:CPD-110
database_cross_reference: PDBeChem:SAL
database_cross_reference: PMID:11016405
database_cross_reference: PMID:12865403
database_cross_reference: PMID:1650428
database_cross_reference: PMID:19400653
database_cross_reference: PMID:19816125
database_cross_reference: PMID:22770225
database_cross_reference: PMID:29079364
database_cross_reference: PMID:32807953
database_cross_reference: PMID:3425858
database_cross_reference: Reaxys:774890
database_cross_reference: Wikipedia:Salicylic_Acid
has exact synonym: 2-hydroxybenzoic acid
has exact synonym: Salicylic acid
has_obo_namespace: chebi_ontology
has_related_synonym: 2-HYDROXYBENZOIC ACID
has_related_synonym: 2-carboxyphenol
has_related_synonym: o-Hydroxybenzoic acid
has_related_synonym: o-carboxyphenol
has_related_synonym: o-hydroxybenzoic acid
id: CHEBI:16914
in subset: 3 STAR

Desacetyl-nitazoxanide
type: Class
subclass of: CHEBI_53443
definition source: Reference: PMID: 33031085
imported from: chebi.owl
charge: 0
formula: C10H7N3O4S
inchi: InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
inchikey: FDTZUTSGGSRHQF-UHFFFAOYSA-N
mass: 265.240
monoisotopicmass: 265.01573
smiles: S1C(NC(=O)C=2C(O)=CC=CC2)=NC=C1[N+]([O-])=O
database_cross_reference: CAS:173903-47-4
database_cross_reference: Chemspider:349588
database_cross_reference: HMDB:HMDB0060597
has exact synonym: 2-hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide
has_obo_namespace: chebi_ontology
id: CHEBI:169666
in subset: 2 STAR

deoxyribonucleic acid
type: Class
subclass of: nucleic acid
editor preferred label: deoxyribonucleic acid
definition: High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
imported from: chebi.owl
imported from: obi.owl

camostat(1+)
type: Class
subclass of: CHEBI_60251
subclass of: Restriction
  on property: is conjugate acid of
  some values from: camostat
definition: A guanidinium ion resulting from the protonation of the guanidyl group of camostat. Major microspecies at pH 7.3.
imported from: chebi.owl
charge: +1
formula: C20H23N4O5
inchi: InChI=1S/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)/p+1
inchikey: XASIMHXSUQUHLV-UHFFFAOYSA-O
mass: 399.426
monoisotopicmass: 399.16630
has_obo_namespace: chebi_ontology
has_related_synonym: camostat cation
id: CHEBI:169939
in subset: 3 STAR

D-phenylalanine
type: Class
subclass of: D-alpha-amino acid
subclass of: phenylalanine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-phenylalaninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-phenylalaninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-phenylalanine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_57981
definition: The D-enantiomer of phenylalanine.
imported from: chebi.owl
charge: 0
formula: C9H11NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
inchikey: COLNVLDHVKWLRT-MRVPVSSYSA-N
mass: 165.18918
monoisotopicmass: 165.07898
smiles: N[C@H](Cc1ccccc1)C(O)=O
has_alternative_id: CHEBI:13007
has_alternative_id: CHEBI:21067
has_alternative_id: CHEBI:42207
has_alternative_id: CHEBI:4224
database_cross_reference: Beilstein:2804068
database_cross_reference: CAS:673-06-3
database_cross_reference: DrugBank:DB02556
database_cross_reference: ECMDB:ECMDB20144
database_cross_reference: Gmelin:83219
database_cross_reference: KEGG:C02265
database_cross_reference: MetaCyc:CPD-216
database_cross_reference: PDBeChem:DPN
database_cross_reference: PMID:22382026
database_cross_reference: PMID:22397264
database_cross_reference: PMID:24464217
database_cross_reference: PMID:7114516
database_cross_reference: Reaxys:2804068
database_cross_reference: YMDB:YMDB00995
has exact synonym: (2R)-2-amino-3-phenylpropanoic acid
has exact synonym: D-PHENYLALANINE
has exact synonym: D-Phenylalanine
has exact synonym: D-phenylalanine
has_obo_namespace: chebi_ontology
has_related_synonym: D-Phe
has_related_synonym: D-alpha-Amino-beta-phenylpropionic acid
has_related_synonym: DPN
has_related_synonym: phenylalanine D-form
id: CHEBI:16998
in subset: 3 STAR

Nirmatrelvir
type: Class
subclass of: secondary carboxamide
subclass of: tertiary carboxamide
subclass of: azabicyclohexane
subclass of: nitrile
subclass of: CHEBI_37143
subclass of: CHEBI_46770
subclass of: CHEBI_74223
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000050274
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
definition: An azabicyclohexane that is (1R,5S)-3-azabicyclo[3.1.0]hexane substituted by {(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}aminoacyl, 3-methyl-N-(trifluoroacetyl)-L-valinamide, methyl and methyl groups at positions 2S, 3, 6 and 6, respectively. It is an inhibitor of SARS-CoV-2 main protease which is currently under clinical development for the treatment of COVID-19.
imported from: chebi.owl
charge: 0
formula: C23H32F3N5O4
inchi: InChI=1S/C23H32F3N5O4/c1-21(2,3)16(30-20(35)23(24,25)26)19(34)31-10-13-14(22(13,4)5)15(31)18(33)29-12(9-27)8-11-6-7-28-17(11)32/h11-16H,6-8,10H2,1-5H3,(H,28,32)(H,29,33)(H,30,35)/t11-,12-,13-,14-,15-,16+/m0/s1
inchikey: LIENCHBZNNMNKG-OJFNHCPVSA-N
mass: 499.535
monoisotopicmass: 499.24064
has exact synonym: (1R,2S,5S)-N-{(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
has_obo_namespace: chebi_ontology
has_related_synonym: PF 07321332
has_related_synonym: PF07321332
id: CHEBI:170007
in subset: 3 STAR
label: PF-07321332

azabicyclohexane
type: Class
subclass of: organic heterobicyclic compound
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: azabicyclohexane derivative
has_related_synonym: azabicyclohexane derivatives
has_related_synonym: azabicyclohexanes
id: CHEBI:170008
in subset: 3 STAR

EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
type: Class
subclass of: CHEBI_38234
definition: A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
imported from: chebi.owl
database_cross_reference: Wikipedia:RNA-dependent_RNA_polymerase
has_obo_namespace: chebi_ontology
has_related_synonym: 3D polymerase inhibitor
has_related_synonym: 3D polymerase inhibitors
has_related_synonym: EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitors
has_related_synonym: EC 2.7.7.48 inhibitor
has_related_synonym: EC 2.7.7.48 inhibitors
has_related_synonym: PB1 proteins inhibitor
has_related_synonym: PB1 proteins inhibitors
has_related_synonym: PB2 proteins inhibitor
has_related_synonym: PB2 proteins inhibitors
has_related_synonym: Q-beta replicase inhibitor
has_related_synonym: Q-beta replicase inhibitors
has_related_synonym: RDRP inhibitor
has_related_synonym: RDRP inhibitors
has_related_synonym: RNA nucleotidyltransferase (RNA-directed) inhibitor
has_related_synonym: RNA nucleotidyltransferase (RNA-directed) inhibitors
has_related_synonym: RNA replicase inhibitor
has_related_synonym: RNA replicase inhibitors
has_related_synonym: RNA synthetase inhibitor
has_related_synonym: RNA synthetase inhibitors
has_related_synonym: RNA transcriptase inhibitor
has_related_synonym: RNA transcriptase inhibitors
has_related_synonym: RNA-dependent RNA polymerase inhibitor
has_related_synonym: RNA-dependent RNA polymerase inhibitors
has_related_synonym: RNA-dependent RNA replicase inhibitor
has_related_synonym: RNA-dependent RNA replicase inhibitors
has_related_synonym: RNA-dependent ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: RNA-dependent ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: RNA-directed RNA polymerase inhibitor
has_related_synonym: RNA-directed RNA polymerase inhibitors
has_related_synonym: phage f2 replicase inhibitor
has_related_synonym: phage f2 replicase inhibitors
has_related_synonym: polymerase L inhibitor
has_related_synonym: polymerase L inhibitors
has_related_synonym: ribonucleic acid replicas inhibitor
has_related_synonym: ribonucleic acid replicas inhibitors
has_related_synonym: ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitor
has_related_synonym: ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitors
has_related_synonym: ribonucleic acid-dependent ribonucleic acid polymeras inhibitor
has_related_synonym: ribonucleic acid-dependent ribonucleic acid polymeras inhibitors
has_related_synonym: ribonucleic replicase inhibitor
has_related_synonym: ribonucleic replicase inhibitors
has_related_synonym: ribonucleic synthetase inhibitor
has_related_synonym: ribonucleic synthetase inhibitors
id: CHEBI:170010
in subset: 3 STAR

progesterone
type: Class
subclass of: CHEBI_36885
subclass of: CHEBI_47909
subclass of: CHEBI_64600
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR_000011650
subclass of: Restriction
  on property: chemical binds protein
  some values from: PR_000032038
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49323
subclass of: Restriction
  on property: has role
  some values from: CHEBI_59826
subclass of: Restriction
  on property: has role
  some values from: CHEBI_70709
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: protein binder
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48706
subclass of: Restriction
  on property: has parent hydride
  some values from: CHEBI 8386
definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
definition source: Reference: PMID: 21084640
imported from: chebi.owl
charge: 0
formula: C21H30O2
inchi: InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
inchikey: RJKFOVLPORLFTN-LEKSSAKUSA-N
mass: 314.46170
monoisotopicmass: 314.22458
has_alternative_id: CHEBI:14896
has_alternative_id: CHEBI:18798
has_alternative_id: CHEBI:26269
has_alternative_id: CHEBI:439
has_alternative_id: CHEBI:45786
has_alternative_id: CHEBI:8453
database_cross_reference: Beilstein:1915950
database_cross_reference: CAS:57-83-0
database_cross_reference: DrugBank:DB00396
database_cross_reference: Drug_Central:2279
database_cross_reference: Gmelin:708590
database_cross_reference: HMDB:HMDB0001830
database_cross_reference: KEGG:C00410
database_cross_reference: KEGG:D00066
database_cross_reference: MetaCyc:PROGESTERONE
database_cross_reference: PDBeChem:STR
database_cross_reference: PMID:10438974
database_cross_reference: PMID:9506942
database_cross_reference: Reaxys:1915950
database_cross_reference: Wikipedia:Progesterone
has exact synonym: PROGESTERONE
has exact synonym: Progesterone
has exact synonym: pregn-4-ene-3,20-dione
has exact synonym: progesterone
has_obo_namespace: chebi_ontology
has_related_synonym: (S)-4-Pregnene-3,20-dione
has_related_synonym: (S)-Pregn-4-en-3,20-dione
has_related_synonym: (S)-Progesterone
has_related_synonym: 17alpha-progesterone
has_related_synonym: 4-Pregnene-3,20-dione
has_related_synonym: Agolutin
has_related_synonym: Akrolutin
has_related_synonym: Crinone
has_related_synonym: Delta(4)-pregnene-3,20-dione
has_related_synonym: Gelbkoerperhormon
has_related_synonym: Progesteron
has_related_synonym: corpus luteum hormone
has_related_synonym: luteohormone
id: CHEBI:17026
in subset: 3 STAR

primary aliphatic amine
type: Class
subclass of: primary amine
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_58001
imported from: chebi.owl
charge: 0
formula: CH4NR
mass: 30.04920
monoisotopicmass: 30.03437
smiles: NC[*]
has_alternative_id: CHEBI:13431
has_alternative_id: CHEBI:8749
database_cross_reference: KEGG:C00375
has_obo_namespace: chebi_ontology
has_related_synonym: RCH2NH2
has_related_synonym: primary aliphatic amines
id: CHEBI:17062
in subset: 3 STAR

ketone
type: Class
subclass of: CHEBI_36586
definition: A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: COR2
mass: 28.010
monoisotopicmass: 27.99491
smiles: [*]C([*])=O
has_alternative_id: CHEBI:13427
has_alternative_id: CHEBI:13646
has_alternative_id: CHEBI:24974
has_alternative_id: CHEBI:6127
has_alternative_id: CHEBI:8742
database_cross_reference: KEGG COMPOUND:C00709
database_cross_reference: KEGG COMPOUND:C01450
database_cross_reference: KEGG:C01450
database_cross_reference: Wikipedia:Ketone
has exact synonym: Ketone
has exact synonym: ketones
has_obo_namespace: chebi_ontology
has_related_synonym: COR2
has_related_synonym: Keton
has_related_synonym: R-CO-R'
has_related_synonym: [*]C([*])=O
has_related_synonym: a ketone
has_related_synonym: cetone
has_related_synonym: ketones
id: CHEBI:17087
in subset: 3 STAR

phosphoramide
type: Class
subclass of: primary amide
subclass of: Restriction
  on property: has functional parent
  some values from: phosphoric acid
definition: A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2).
imported from: chebi.owl
has_alternative_id: CHEBI:14827
has_alternative_id: CHEBI:26076
has_alternative_id: CHEBI:8162
has_obo_namespace: chebi_ontology
has_related_synonym: phosphamide
has_related_synonym: phosphamides
has_related_synonym: phosphoramides
id: CHEBI:17102
in subset: 3 STAR

L-serine
type: Class
subclass of: L-alpha-amino acid
subclass of: serine
subclass of: serine family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-serinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-serinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-serine
subclass of: Restriction
  on property: is tautomer of
  some values from: L-serine zwitterion
definition: The L-enantiomer of serine.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
inchikey: MTCFGRXMJLQNBG-REOHCLBHSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: N[C@@H](CO)C(O)=O
has_alternative_id: CHEBI:13167
has_alternative_id: CHEBI:21387
has_alternative_id: CHEBI:45440
has_alternative_id: CHEBI:45451
has_alternative_id: CHEBI:45590
has_alternative_id: CHEBI:45597
has_alternative_id: CHEBI:45677
has_alternative_id: CHEBI:6301
database_cross_reference: Beilstein:1721404
database_cross_reference: CAS:56-45-1
database_cross_reference: DrugBank:DB00133
database_cross_reference: Drug_Central:4127
database_cross_reference: ECMDB:ECMDB00187
database_cross_reference: Gmelin:2570
database_cross_reference: HMDB:HMDB0000187
database_cross_reference: KEGG:C00065
database_cross_reference: KEGG:D00016
database_cross_reference: KNApSAcK:C00001393
database_cross_reference: MetaCyc:SER
database_cross_reference: PDBeChem:SER
database_cross_reference: PMID:1650428
database_cross_reference: PMID:17439666
database_cross_reference: PMID:19062365
database_cross_reference: PMID:21956576
database_cross_reference: PMID:22265470
database_cross_reference: PMID:22393170
database_cross_reference: PMID:22547037
database_cross_reference: PMID:22566084
database_cross_reference: PMID:22566694
database_cross_reference: Reaxys:1721404
database_cross_reference: Wikipedia:L-serine
database_cross_reference: YMDB:YMDB00112
has exact synonym: L-Serine
has exact synonym: L-serine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-hydroxypropanoic acid
has_related_synonym: (S)-(-)-serine
has_related_synonym: (S)-2-amino-3-hydroxypropanoic acid
has_related_synonym: (S)-alpha-Amino-beta-hydroxypropionic acid
has_related_synonym: (S)-serine
has_related_synonym: L-(-)-serine
has_related_synonym: L-2-Amino-3-hydroxypropionic acid
has_related_synonym: L-3-Hydroxy-2-aminopropionic acid
has_related_synonym: L-3-Hydroxy-alanine
has_related_synonym: L-Ser
has_related_synonym: L-Serin
has_related_synonym: S
has_related_synonym: SERINE
has_related_synonym: Ser
has_related_synonym: Serine
has_related_synonym: beta-Hydroxy-L-alanine
has_related_synonym: beta-Hydroxyalanine
id: CHEBI:17115
in subset: 3 STAR

hexanoate
type: Class
subclass of: CHEBI_58951
subclass of: CHEBI_58954
subclass of: CHEBI_78116
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: hexanoic acid
definition: A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid).
imported from: chebi.owl
charge: -1
formula: C6H11O2
inchi: InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)/p-1
inchikey: FUZZWVXGSFPDMH-UHFFFAOYSA-M
mass: 115.15034
monoisotopicmass: 115.07645
smiles: CCCCCC([O-])=O
has_alternative_id: CHEBI:14398
has_alternative_id: CHEBI:24569
database_cross_reference: Beilstein:3601453
database_cross_reference: CAS:151-33-7
database_cross_reference: ECMDB:ECMDB21229
database_cross_reference: Gmelin:326340
database_cross_reference: KEGG:C01585
database_cross_reference: MetaCyc:HEXANOATE
has exact synonym: hexanoate
has_obo_namespace: chebi_ontology
has_related_synonym: 1-hexanoate
has_related_synonym: 1-pentacarboxylate
has_related_synonym: 1-pentanecarboxylate
has_related_synonym: CH3-[CH2]4-COO(-)
has_related_synonym: butylacetate
has_related_synonym: caproate
has_related_synonym: capronate
has_related_synonym: hexoate
has_related_synonym: hexylate
has_related_synonym: n-caproate
has_related_synonym: n-hexanoate
has_related_synonym: n-hexoate
has_related_synonym: n-hexylate
has_related_synonym: nPnCO2 anion
has_related_synonym: pentanecarboxylate
has_related_synonym: pentylformate
id: CHEBI:17120
in subset: 3 STAR

carnitine
type: Class
subclass of: amino-acid betaine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has functional parent
  some values from: butyrate
subclass of: Restriction
  on property: is conjugate base of
  some values from: carnitinium
definition: An amino-acid betaine that is butanoate substituted with a hydroxy group at position C-3 and a trimethylammonium group at C-4.
imported from: chebi.owl
charge: 0
formula: C7H15NO3
inchi: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3
inchikey: PHIQHXFUZVPYII-UHFFFAOYSA-N
mass: 161.19894
monoisotopicmass: 161.10519
smiles: C[N+](C)(C)CC(O)CC([O-])=O
has_alternative_id: CHEBI:11817
has_alternative_id: CHEBI:13947
has_alternative_id: CHEBI:20047
has_alternative_id: CHEBI:23038
database_cross_reference: Beilstein:1866665
database_cross_reference: CAS:461-06-3
database_cross_reference: DrugBank:DB02648
database_cross_reference: KEGG:C00487
database_cross_reference: MetaCyc:DL-CARNITINE
database_cross_reference: PMID:22770225
database_cross_reference: PMID:23868375
database_cross_reference: Patent:US4255449
database_cross_reference: Patent:US4315944
database_cross_reference: Reaxys:1866665
database_cross_reference: Wikipedia:Carnitine
has exact synonym: 3-hydroxy-4-(trimethylammonio)butanoate
has exact synonym: carnitine
has_obo_namespace: chebi_ontology
has_related_synonym: D,L-carnitine
id: CHEBI:17126
in subset: 3 STAR

hydrogensulfite
type: Class
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfite
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_48854
imported from: chebi.owl
charge: -1
formula: HO3S
inchi: InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1
inchikey: LSNNMFCWUKXFEE-UHFFFAOYSA-M
mass: 81.07214
monoisotopicmass: 80.96519
smiles: OS([O-])=O
has_alternative_id: CHEBI:13367
has_alternative_id: CHEBI:5598
database_cross_reference: CAS:15181-46-1
database_cross_reference: Gmelin:1455
database_cross_reference: KEGG:C11481
database_cross_reference: PDBeChem:SO3
has exact synonym: hydrogen(trioxidosulfate)(1-)
has exact synonym: hydrogensulfite(1-)
has exact synonym: hydrogentrioxosulfate(1-)
has exact synonym: hydrogentrioxosulfate(IV)
has exact synonym: hydroxidodioxidosulfate(1-)
has exact synonym: monohydrogentrioxosulfate
has_obo_namespace: chebi_ontology
has_related_synonym: Bisulfite
has_related_synonym: HSO3(-)
has_related_synonym: HSO3-
has_related_synonym: Hydrogen sulfite
has_related_synonym: [SO2(OH)](-)
has_related_synonym: bisulfite
has_related_synonym: bisulphite
has_related_synonym: hydrogen sulfite(1-)
has_related_synonym: hydrosulfite anion
id: CHEBI:17137
in subset: 3 STAR

antiamoebic agent
type: Class
subclass of: antiparasitic agent
definition: An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: amebicide
has_related_synonym: amebicides
has_related_synonym: amoebicide
has_related_synonym: amoebicides
has_related_synonym: anti-amoebic agent
has_related_synonym: anti-amoebic agents
has_related_synonym: anti-amoebic drug
has_related_synonym: anti-amoebic drugs
has_related_synonym: antiamoebic
has_related_synonym: antiamoebic agents
has_related_synonym: antiamoebic drug
has_related_synonym: antiamoebic drugs
has_related_synonym: antiamoebics
id: CHEBI:171664
in subset: 3 STAR

L-asparagine
type: Class
subclass of: L-alpha-amino acid
subclass of: asparagine
subclass of: aspartate family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-asparaginate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-asparaginium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-asparagine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_58048
definition: An optically active form of asparagine having L-configuration.
imported from: chebi.owl
charge: 0
formula: C4H8N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
inchikey: DCXYFEDJOCDNAF-REOHCLBHSA-N
mass: 132.11800
monoisotopicmass: 132.05349
smiles: N[C@@H](CC(N)=O)C(O)=O
has_alternative_id: CHEBI:13083
has_alternative_id: CHEBI:21242
has_alternative_id: CHEBI:40902
has_alternative_id: CHEBI:6191
database_cross_reference: Beilstein:1723527
database_cross_reference: CAS:70-47-3
database_cross_reference: DrugBank:DB00174
database_cross_reference: Drug_Central:4126
database_cross_reference: ECMDB:ECMDB00168
database_cross_reference: FooDB:FDB000787
database_cross_reference: Gmelin:3334
database_cross_reference: HMDB:HMDB0000168
database_cross_reference: KEGG:C00152
database_cross_reference: KNApSAcK:C00001341
database_cross_reference: MetaCyc:ASN
database_cross_reference: PDBeChem:ASN
database_cross_reference: PMID:12142634
database_cross_reference: PMID:15907185
database_cross_reference: PMID:16190636
database_cross_reference: PMID:16368161
database_cross_reference: PMID:16668324
database_cross_reference: PMID:17497286
database_cross_reference: PMID:21800258
database_cross_reference: PMID:21854356
database_cross_reference: PMID:22513289
database_cross_reference: Reaxys:1723527
database_cross_reference: Wikipedia:Asparagine
database_cross_reference: YMDB:YMDB00226
has exact synonym: L-Asparagine
has exact synonym: L-asparagine
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2,4-diamino-4-oxobutanoic acid
has_related_synonym: (2S)-2-amino-3-carbamoylpropanoic acid
has_related_synonym: (S)-2-amino-3-carbamoylpropanoic acid
has_related_synonym: (S)-Asparagine
has_related_synonym: 2-Aminosuccinamic acid
has_related_synonym: ASPARAGINE
has_related_synonym: Asn
has_related_synonym: Aspartamic acid
has_related_synonym: L-2-aminosuccinamic acid
has_related_synonym: L-Asparagin
has_related_synonym: L-aspartic acid beta-amide
has_related_synonym: N
has_related_synonym: alpha-aminosuccinamic acid
id: CHEBI:17196
in subset: 3 STAR

L-proline
type: Class
subclass of: L-alpha-amino acid
subclass of: glutamine family amino acid
subclass of: proline
subclass of: CHEBI_83813
definition: Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.
imported from: chebi.owl
charge: 0
formula: C5H9NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
inchikey: ONIBWKKTOPOVIA-BYPYZUCNSA-N
mass: 115.13050
monoisotopicmass: 115.06333
smiles: OC(=O)[C@@H]1CCCN1
has_alternative_id: CHEBI:13154
has_alternative_id: CHEBI:184637
has_alternative_id: CHEBI:21373
has_alternative_id: CHEBI:42067
has_alternative_id: CHEBI:45040
has_alternative_id: CHEBI:45100
has_alternative_id: CHEBI:45159
has_alternative_id: CHEBI:6286
database_cross_reference: Beilstein:80810
database_cross_reference: CAS:147-85-3
database_cross_reference: DrugBank:DB00172
database_cross_reference: Drug_Central:4125
database_cross_reference: Gmelin:50152
database_cross_reference: HMDB:HMDB0000162
database_cross_reference: KEGG:C00148
database_cross_reference: KEGG:D00035
database_cross_reference: KNApSAcK:C00001388
database_cross_reference: MetaCyc:PRO
database_cross_reference: PDBeChem:PRO
database_cross_reference: PMID:11076505
database_cross_reference: PMID:12770004
database_cross_reference: PMID:14975886
database_cross_reference: PMID:15576824
database_cross_reference: PMID:15838615
database_cross_reference: PMID:15894682
database_cross_reference: PMID:15973048
database_cross_reference: PMID:16033917
database_cross_reference: PMID:16190672
database_cross_reference: PMID:16501220
database_cross_reference: PMID:16656443
database_cross_reference: PMID:16657874
database_cross_reference: PMID:16668324
database_cross_reference: PMID:17127472
database_cross_reference: PMID:17608428
database_cross_reference: PMID:18551589
database_cross_reference: PMID:18802692
database_cross_reference: PMID:18973300
database_cross_reference: PMID:19215998
database_cross_reference: PMID:19580280
database_cross_reference: PMID:19656302
database_cross_reference: PMID:19688381
database_cross_reference: PMID:19811425
database_cross_reference: PMID:22139509
database_cross_reference: PMID:22201772
database_cross_reference: PMID:22451406
database_cross_reference: PMID:22475019
database_cross_reference: PMID:22482728
database_cross_reference: PMID:22491679
database_cross_reference: PMID:22770225
database_cross_reference: Reaxys:80810
database_cross_reference: Wikipedia:L-proline
has exact synonym: L-Proline
has exact synonym: L-proline
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-(S)-proline
has_related_synonym: (-)-2-pyrrolidinecarboxylic acid
has_related_synonym: (-)-proline
has_related_synonym: (2S)-pyrrolidine-2-carboxylic acid
has_related_synonym: (S)-2-carboxypyrrolidine
has_related_synonym: (S)-2-pyrrolidinecarboxylic acid
has_related_synonym: (S)-pyrrolidine-2-carboxylic acid
has_related_synonym: 2-Pyrrolidinecarboxylic acid
has_related_synonym: L-(-)-proline
has_related_synonym: L-Prolin
has_related_synonym: L-alpha-pyrrolidinecarboxylic acid
has_related_synonym: L-pyrrolidine-2-carboxylic acid

7H-purine
type: Class
subclass of: purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 1H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 3H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 9H-purine
definition: The 7H-tautomer of purine.
imported from: chebi.owl
charge: 0
formula: C5H4N4
inchi: InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
inchikey: KDCGOANMDULRCW-UHFFFAOYSA-N
mass: 120.11222
monoisotopicmass: 120.04360
smiles: c1ncc2[nH]cnc2n1
has_alternative_id: CHEBI:14968
has_alternative_id: CHEBI:8639
database_cross_reference: Beilstein:3200
database_cross_reference: Gmelin:601779
database_cross_reference: HMDB:HMDB0001366
database_cross_reference: KEGG:C15587
database_cross_reference: Reaxys:3200
has exact synonym: 7H-purine
has_obo_namespace: chebi_ontology
has_related_synonym: Purine
has_related_synonym: Purine base
id: CHEBI:17258
in subset: 3 STAR

propionate
type: Class
subclass of: CHEBI_78113
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: propionic acid
definition: The conjugate base of propionic acid; a key precursor in lipid biosynthesis.
imported from: chebi.owl
charge: -1
formula: C3H5O2
inchi: InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)/p-1
inchikey: XBDQKXXYIPTUBI-UHFFFAOYSA-M
mass: 73.07060
monoisotopicmass: 73.02950
smiles: CCC([O-])=O
has_alternative_id: CHEBI:14903
has_alternative_id: CHEBI:26290
database_cross_reference: Beilstein:3587503
database_cross_reference: CAS:72-03-7
database_cross_reference: Gmelin:1820
database_cross_reference: KEGG:C00163
database_cross_reference: PMID:17951291
database_cross_reference: PMID:18375549
database_cross_reference: PMID:2647392
database_cross_reference: UM-BBD_compID:c0277
has exact synonym: propanoate
has exact synonym: propionate
has_obo_namespace: chebi_ontology
has_related_synonym: CH3-CH2-COO(-)
has_related_synonym: EtCO2 anion
has_related_synonym: carboxylatoethane
has_related_synonym: ethanecarboxylate
has_related_synonym: ethylformate
has_related_synonym: metacetonate
has_related_synonym: methylacetate
has_related_synonym: propanate
has_related_synonym: propanoate
has_related_synonym: propanoic acid, ion(1-)
has_related_synonym: pseudoacetate
id: CHEBI:17272
in subset: 3 STAR

L-phenylalanine
type: Class
subclass of: L-alpha-amino acid
subclass of: phenylalanine
subclass of: CHEBI_73690
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63332
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76967
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-phenylalaninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-phenylalaninium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-phenylalanine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_58095
definition: The L-enantiomer of phenylalanine.
imported from: chebi.owl
charge: 0
formula: C9H11NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
inchikey: COLNVLDHVKWLRT-QMMMGPOBSA-N
mass: 165.18918
monoisotopicmass: 165.07898
smiles: N[C@@H](Cc1ccccc1)C(O)=O
has_alternative_id: CHEBI:13151
has_alternative_id: CHEBI:21370
has_alternative_id: CHEBI:44851
has_alternative_id: CHEBI:44885
has_alternative_id: CHEBI:45079
has_alternative_id: CHEBI:6282
database_cross_reference: Beilstein:1910408
database_cross_reference: CAS:63-91-2
database_cross_reference: DrugBank:DB00120
database_cross_reference: Drug_Central:2144
database_cross_reference: ECMDB:ECMDB00159
database_cross_reference: Gmelin:50837
database_cross_reference: HMDB:HMDB0000159
database_cross_reference: KEGG:C00079
database_cross_reference: KEGG:D00021
database_cross_reference: KNApSAcK:C00001386
database_cross_reference: MetaCyc:PHE
database_cross_reference: PDBeChem:PHE
database_cross_reference: PMID:13945318
database_cross_reference: PMID:16893175
database_cross_reference: PMID:17784858
database_cross_reference: PMID:21203787
database_cross_reference: PMID:21956539
database_cross_reference: PMID:22081386
database_cross_reference: PMID:22112574
database_cross_reference: PMID:22143120
database_cross_reference: PMID:22209218
database_cross_reference: PMID:22494897
database_cross_reference: PMID:23836015
database_cross_reference: PMID:24464217
database_cross_reference: PMID:24733517
database_cross_reference: PMID:24966042
database_cross_reference: Reaxys:1910408
database_cross_reference: Wikipedia:Phenylalanine
database_cross_reference: YMDB:YMDB00304
has exact synonym: (2S)-2-amino-3-phenylpropanoic acid
has exact synonym: L-Phenylalanine
has exact synonym: L-phenylalanine
has_obo_namespace: chebi_ontology
has_related_synonym: (S)-2-Amino-3-phenylpropionic acid
has_related_synonym: (S)-alpha-Amino-beta-phenylpropionic acid
has_related_synonym: 3-phenyl-L-alanine
has_related_synonym: F
has_related_synonym: PHENYLALANINE
has_related_synonym: Phe
has_related_synonym: beta-phenyl-L-alanine
id: CHEBI:17295
in subset: 3 STAR

aniline
type: Class
subclass of: anilines
subclass of: CHEBI_50471
definition: A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens.
imported from: chebi.owl
charge: 0
formula: C6H7N
inchi: InChI=1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
inchikey: PAYRUJLWNCNPSJ-UHFFFAOYSA-N
mass: 93.12650
monoisotopicmass: 93.05785
smiles: Nc1ccccc1
has_alternative_id: CHEBI:13834
has_alternative_id: CHEBI:22561
has_alternative_id: CHEBI:2732
has_alternative_id: CHEBI:40796
database_cross_reference: Beilstein:605631
database_cross_reference: CAS:62-53-3
database_cross_reference: DrugBank:DB06728
database_cross_reference: Gmelin:2796
database_cross_reference: HMDB:HMDB0003012
database_cross_reference: KEGG:C00292
database_cross_reference: MetaCyc:ANILINE
database_cross_reference: PDBeChem:ANL
database_cross_reference: PMID:11304127
database_cross_reference: PMID:17135213
database_cross_reference: PMID:23821252
database_cross_reference: PMID:3779628
database_cross_reference: PMID:6205897
database_cross_reference: Reaxys:605631
database_cross_reference: Wikipedia:Aniline
has exact synonym: ANILINE
has exact synonym: Aniline
has exact synonym: aniline
has_obo_namespace: chebi_ontology
has_related_synonym: Anilin
has_related_synonym: Benzenamine
has_related_synonym: Phenylamine
has_related_synonym: aminobenzene
has_related_synonym: aminophen
has_related_synonym: benzeneamine
has_related_synonym: kyanol
id: CHEBI:17296
in subset: 3 STAR

ferroptosis inhibitor
type: Class
subclass of: inhibitor
subclass of: CHEBI_52206
definition: Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
imported from: chebi.owl
database_cross_reference: PMID:32015325
database_cross_reference: PMID:32256352
database_cross_reference: PMID:32413317
database_cross_reference: PMID:33495651
database_cross_reference: Wikipedia:Ferroptosis
has_obo_namespace: chebi_ontology
has_related_synonym: ferroptosis inhibitors
id: CHEBI:173084
in subset: 3 STAR

ferroptosis inducer
type: Class
subclass of: CHEBI_52206
definition: Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
imported from: chebi.owl
database_cross_reference: PMID:31899616
database_cross_reference: PMID:32015325
database_cross_reference: PMID:33167414
database_cross_reference: PMID:34012798
database_cross_reference: Wikipedia:Ferroptosis
has_obo_namespace: chebi_ontology
has_related_synonym: ferroptosis inducers
id: CHEBI:173085
in subset: 3 STAR

sulfite
type: Class
subclass of: sulfur oxoanion
subclass of: CHEBI_48154
subclass of: CHEBI_79388
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogensulfite
definition: A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3).
imported from: chebi.owl
charge: -2
formula: O3S
inchi: InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2
inchikey: LSNNMFCWUKXFEE-UHFFFAOYSA-L
mass: 80.06420
monoisotopicmass: 79.95791
smiles: [O-]S([O-])=O
has_alternative_id: CHEBI:15139
has_alternative_id: CHEBI:45548
database_cross_reference: CAS:14265-45-3
database_cross_reference: Gmelin:1449
database_cross_reference: PDBeChem:SO3
has exact synonym: sulfite
has exact synonym: trioxidosulfate(2-)
has exact synonym: trioxosulfate(2-)
has exact synonym: trioxosulfate(IV)
has_obo_namespace: chebi_ontology
has_related_synonym: SO3
has_related_synonym: SO3(2-)
has_related_synonym: SULFITE ION
has_related_synonym: [SO3](2-)
has_related_synonym: sulphite
id: CHEBI:17359
in subset: 3 STAR

O-acylcarnitine
type: Class
subclass of: carboxylic ester
subclass of: ammonium betaine
subclass of: Restriction
  on property: has functional parent
  some values from: carnitine
definition: Any carboxylic ester obtained by the O-acylation of carnitine.
imported from: chebi.owl
has_alternative_id: CHEBI:12712
has_alternative_id: CHEBI:7673
has_obo_namespace: chebi_ontology
id: CHEBI:17387
in subset: 3 STAR

valeric acid
type: Class
subclass of: short-chain fatty acid
subclass of: CHEBI_39418
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate acid of
  some values from: valerate
definition: A straight-chain saturated fatty acid containing five carbon atoms.
imported from: chebi.owl
charge: 0
formula: C5H10O2
inchi: InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
inchikey: NQPDZGIKBAWPEJ-UHFFFAOYSA-N
mass: 102.13170
monoisotopicmass: 102.06808
smiles: CCCCC(O)=O
has_alternative_id: CHEBI:113448
has_alternative_id: CHEBI:27263
has_alternative_id: CHEBI:27264
has_alternative_id: CHEBI:43606
has_alternative_id: CHEBI:44803
has_alternative_id: CHEBI:7980
database_cross_reference: Beilstein:969454
database_cross_reference: CAS:109-52-4
database_cross_reference: DrugBank:DB02406
database_cross_reference: Gmelin:26714
database_cross_reference: HMDB:HMDB0000892
database_cross_reference: KEGG:C00803
database_cross_reference: KNApSAcK:C00001208
database_cross_reference: LIPID_MAPS_instance:LMFA01010005
database_cross_reference: PDBeChem:LEA
database_cross_reference: PMID:20507156
database_cross_reference: PPDB:3130
database_cross_reference: Reaxys:969454
database_cross_reference: Wikipedia:Valeric_acid
has exact synonym: Valeric acid
has exact synonym: pentanoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: 1-butanecarboxylic acid
has_related_synonym: CH3-[CH2]3-COOH
has_related_synonym: PENTANOIC ACID
has_related_synonym: Pentanoate
has_related_synonym: Pentanoic acid
has_related_synonym: Valerate
has_related_synonym: Valerianic acid
has_related_synonym: Valeriansaeure
has_related_synonym: n-BuCOOH
has_related_synonym: n-Pentanoate
has_related_synonym: n-Valeric acid
has_related_synonym: n-pentanoic acid
has_related_synonym: n-valeric acid
has_related_synonym: pentoic acid
has_related_synonym: propylacetic acid
has_related_synonym: valeric acid, normal
id: CHEBI:17418
in subset: 3 STAR

aldehyde
type: Class
subclass of: CHEBI_36586
subclass of: Restriction
  on property: has part
  some values from: CHEBI_42485
definition: A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
imported from: chebi.owl
charge: 0
formula: CHOR
mass: 29.01800
monoisotopicmass: 29.00274
smiles: [H]C([*])=O
has_alternative_id: CHEBI:13432
has_alternative_id: CHEBI:13753
has_alternative_id: CHEBI:13805
has_alternative_id: CHEBI:13806
has_alternative_id: CHEBI:22291
has_alternative_id: CHEBI:2554
has_alternative_id: CHEBI:8750
database_cross_reference: KEGG:C00071
has exact synonym: Aldehyde
has exact synonym: aldehyde
has exact synonym: aldehydes
has_obo_namespace: chebi_ontology
has_related_synonym: Aldehyd
has_related_synonym: RC(=O)H
has_related_synonym: RCHO
has_related_synonym: aldehido
has_related_synonym: aldehidos
has_related_synonym: aldehydes
has_related_synonym: aldehydum
has_related_synonym: an aldehyde
id: CHEBI:17478
in subset: 3 STAR

cyanide
type: Class
subclass of: CHEBI_36828
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38500
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogen cyanide
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_36856
definition: A pseudohalide anion that is the conjugate base of hydrogen cyanide.
imported from: chebi.owl
charge: -1
formula: CN
inchi: InChI=1S/CN/c1-2/q-1
inchikey: XFXPMWWXUTWYJX-UHFFFAOYSA-N
mass: 26.01740
monoisotopicmass: 26.00362
smiles: [C-]#N
has_alternative_id: CHEBI:14038
has_alternative_id: CHEBI:3969
has_alternative_id: CHEBI:41780
database_cross_reference: Beilstein:1900509
database_cross_reference: CAS:57-12-5
database_cross_reference: Gmelin:89
database_cross_reference: HMDB:HMDB0002084
database_cross_reference: KEGG:C00177
database_cross_reference: MetaCyc:CPD-13584
database_cross_reference: PDBeChem:CYN
database_cross_reference: PMID:11386635
database_cross_reference: PMID:14871577
database_cross_reference: PMID:17554165
database_cross_reference: PMID:7839575
database_cross_reference: Reaxys:1900509
database_cross_reference: Wikipedia:Cyanide
has exact synonym: Cyanide
has exact synonym: cyanide
has exact synonym: nitridocarbonate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: CN(-)
has_related_synonym: CN-
has_related_synonym: CYANIDE ION
has_related_synonym: Prussiate
has_related_synonym: Zyanid
id: CHEBI:17514
in subset: 3 STAR

hydrogencarbonate
type: Class
subclass of: carbon oxoanion
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_41609
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbonic acid
definition: The carbon oxoanion resulting from the removal of a proton from carbonic acid.
imported from: chebi.owl
charge: -1
formula: CHO3
inchi: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
inchikey: BVKZGUZCCUSVTD-UHFFFAOYSA-M
mass: 61.01684
monoisotopicmass: 60.99312
smiles: OC([O-])=O
has_alternative_id: CHEBI:13363
has_alternative_id: CHEBI:22863
has_alternative_id: CHEBI:40961
has_alternative_id: CHEBI:5589
database_cross_reference: Beilstein:3903504
database_cross_reference: CAS:71-52-3
database_cross_reference: Gmelin:49249
database_cross_reference: HMDB:HMDB0000595
database_cross_reference: KEGG:C00288
database_cross_reference: MetaCyc:HCO3
database_cross_reference: PDBeChem:BCT
database_cross_reference: PMID:17215880
database_cross_reference: PMID:17505962
database_cross_reference: PMID:18439416
database_cross_reference: PMID:28732801
database_cross_reference: PMID:29150416
database_cross_reference: PMID:29460248
database_cross_reference: PMID:29466234
database_cross_reference: PMID:4208463
database_cross_reference: Wikipedia:Bicarbonate
has exact synonym: Hydrogencarbonate
has exact synonym: hydrogen(trioxidocarbonate)(1-)
has exact synonym: hydrogencarbonate
has exact synonym: hydrogencarbonate(1-)
has exact synonym: hydrogentrioxocarbonate(1-)
has exact synonym: hydrogentrioxocarbonate(IV)
has exact synonym: hydroxidodioxidocarbonate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: Acid carbonate
has_related_synonym: BICARBONATE ION
has_related_synonym: Bicarbonate
has_related_synonym: HCO3(-)
has_related_synonym: HCO3-
has_related_synonym: [CO2(OH)](-)
has_related_synonym: hydrogen carbonate
id: CHEBI:17544
in subset: 3 STAR

L-cysteine
type: Class
subclass of: cysteine
subclass of: L-alpha-amino acid
subclass of: serine family amino acid
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64577
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77703
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-cysteinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-cysteine
subclass of: Restriction
  on property: is tautomer of
  some values from: L-cysteine zwitterion
definition: An optically active form of cysteine having L-configuration.
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
inchikey: XUJNEKJLAYXESH-REOHCLBHSA-N
mass: 121.15800
monoisotopicmass: 121.01975
smiles: N[C@@H](CS)C(O)=O
has_alternative_id: CHEBI:13095
has_alternative_id: CHEBI:21261
has_alternative_id: CHEBI:41227
has_alternative_id: CHEBI:41700
has_alternative_id: CHEBI:41768
has_alternative_id: CHEBI:41781
has_alternative_id: CHEBI:41811
has_alternative_id: CHEBI:6207
database_cross_reference: Beilstein:1721408
database_cross_reference: CAS:52-90-4
database_cross_reference: DrugBank:DB00151
database_cross_reference: Drug_Central:769
database_cross_reference: ECMDB:ECMDB00574
database_cross_reference: Gmelin:49991
database_cross_reference: HMDB:HMDB0000574
database_cross_reference: KEGG:C00097
database_cross_reference: KEGG:D00026
database_cross_reference: KNApSAcK:C00001351
database_cross_reference: MetaCyc:CYS
database_cross_reference: PDBeChem:CYS
database_cross_reference: PMID:11732994
database_cross_reference: PMID:13761469
database_cross_reference: PMID:22735334
database_cross_reference: Reaxys:1721408
database_cross_reference: Wikipedia:Cysteine
database_cross_reference: YMDB:YMDB00046
has exact synonym: L-Cysteine
has exact synonym: L-cysteine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-mercaptopropanoic acid
has_related_synonym: (2R)-2-amino-3-sulfanylpropanoic acid
has_related_synonym: (R)-2-amino-3-mercaptopropanoic acid
has_related_synonym: C
has_related_synonym: CYSTEINE
has_related_synonym: Cys
has_related_synonym: E 920
has_related_synonym: E-920
has_related_synonym: E920
has_related_synonym: FREE CYSTEINE
has_related_synonym: L-2-Amino-3-mercaptopropionic acid
has_related_synonym: L-Cystein
has_related_synonym: L-Zystein
id: CHEBI:17561
in subset: 3 STAR

cytidine
type: Class
subclass of: cytidines
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has functional parent
  some values from: cytosine
definition: A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond.
imported from: chebi.owl
charge: 0
formula: C9H13N3O5
inchi: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
inchikey: UHDGCWIWMRVCDJ-XVFCMESISA-N
mass: 243.21674
monoisotopicmass: 243.08552
has_alternative_id: CHEBI:14063
has_alternative_id: CHEBI:23515
has_alternative_id: CHEBI:4053
has_alternative_id: CHEBI:41649
has_alternative_id: CHEBI:41686
has_alternative_id: CHEBI:41704
database_cross_reference: Beilstein:89173
database_cross_reference: CAS:65-46-3
database_cross_reference: DrugBank:DB02097
database_cross_reference: Gmelin:84763
database_cross_reference: HMDB:HMDB0000089
database_cross_reference: KEGG:C00475
database_cross_reference: KEGG:D07769
database_cross_reference: MetaCyc:CYTIDINE
database_cross_reference: PDBeChem:CTN
database_cross_reference: PMID:12591866
database_cross_reference: PMID:15621516
database_cross_reference: PMID:19194376
database_cross_reference: Reaxys:89173
database_cross_reference: Wikipedia:Cytidine
has exact synonym: Cytidine
has exact synonym: cytidine
has_obo_namespace: chebi_ontology
has_related_synonym: 1-beta-D-Ribofuranosylcytosine
has_related_synonym: 1beta-D-ribofuranosylcytosine
has_related_synonym: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE
has_related_synonym: 4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one
has_related_synonym: 4-amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone
has_related_synonym: Cyd
has_related_synonym: Cytidin
has_related_synonym: Cytosine riboside
has_related_synonym: Zytidin
has_related_synonym: cytosine-1beta-D-Ribofuranoside
id: CHEBI:17562
in subset: 3 STAR

toluene
type: Class
subclass of: volatile organic compound
subclass of: toluenes
subclass of: CHEBI_38975
definition: The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
imported from: chebi.owl
charge: 0
formula: C7H8
inchi: InChI=1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
inchikey: YXFVVABEGXRONW-UHFFFAOYSA-N
mass: 92.13842
monoisotopicmass: 92.06260
smiles: Cc1ccccc1
has_alternative_id: CHEBI:15248
has_alternative_id: CHEBI:27022
has_alternative_id: CHEBI:44023
has_alternative_id: CHEBI:9624
database_cross_reference: Beilstein:635760
database_cross_reference: CAS:108-88-3
database_cross_reference: DrugBank:DB01900
database_cross_reference: Gmelin:2456
database_cross_reference: KEGG:C01455
database_cross_reference: PDBeChem:MBN
database_cross_reference: PMID:11182169
database_cross_reference: PMID:11314682
database_cross_reference: PMID:11846266
database_cross_reference: PMID:11991009
database_cross_reference: PMID:12062755
database_cross_reference: PMID:12213539
database_cross_reference: PMID:12237258
database_cross_reference: PMID:12784113
database_cross_reference: PMID:12876426
database_cross_reference: PMID:14512097
database_cross_reference: PMID:14559343
database_cross_reference: PMID:14605898
database_cross_reference: PMID:15015825
database_cross_reference: PMID:15019953
database_cross_reference: PMID:15119846
database_cross_reference: PMID:15193425
database_cross_reference: PMID:15542760
database_cross_reference: PMID:15567510
database_cross_reference: PMID:15695158
database_cross_reference: PMID:15796064
database_cross_reference: PMID:16316648
database_cross_reference: PMID:16348226
database_cross_reference: PMID:16601996
database_cross_reference: PMID:17145141
database_cross_reference: PMID:17175136
database_cross_reference: PMID:17497535
database_cross_reference: PMID:17725881
database_cross_reference: PMID:18397809
database_cross_reference: PMID:18832024
database_cross_reference: PMID:19261054
database_cross_reference: PMID:19384711
database_cross_reference: PMID:19429395
database_cross_reference: PMID:19635754
database_cross_reference: PMID:19765629
database_cross_reference: PMID:19825861
database_cross_reference: PMID:19928203
database_cross_reference: PMID:19969016
database_cross_reference: PMID:20347282
database_cross_reference: PMID:20837561
database_cross_reference: PMID:21430649
database_cross_reference: PMID:21655021
database_cross_reference: PMID:21731073
database_cross_reference: PMID:21802510
database_cross_reference: PMID:21840036
database_cross_reference: Reaxys:635760
database_cross_reference: UM-BBD_compID:c0114
database_cross_reference: Wikipedia:Toluene
has exact synonym: TOLUENE
has exact synonym: Toluene
has exact synonym: toluene
has_obo_namespace: chebi_ontology
has_related_synonym: Toluen
has_related_synonym: Toluol
has_related_synonym: methylbenzene
has_related_synonym: phenylmethane
id: CHEBI:17578
in subset: 3 STAR

gemcitabine
type: Class
subclass of: pyrimidine 2'-deoxyribonucleoside
subclass of: CHEBI_37143
has_RxCUI: 12574
definition: A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
definition: A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. Gemcitabine is used in various carcinomas: non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
definition source: https://www.drugbank.ca/drugs/DB00441
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C9H11F2N3O4
inchi: InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1
inchikey: SDUQYLNIPVEERB-QPPQHZFASA-N
mass: 263.19810
monoisotopicmass: 263.07176
has_alternative_id: CHEBI:42752
has_alternative_id: CHEBI:5295
database_cross_reference: Beilstein:5382060
database_cross_reference: CAS:95058-81-4
database_cross_reference: ChEMBL:11356111
database_cross_reference: ChEMBL:17101674
database_cross_reference: ChEMBL:175901
database_cross_reference: ChEMBL:17602464
database_cross_reference: ChEMBL:17887663
database_cross_reference: ChEMBL:17939651
database_cross_reference: ChEMBL:18186604
database_cross_reference: ChEMBL:18257544
database_cross_reference: ChemIDplus:95058-81-4
database_cross_reference: CiteXplore:11034044
database_cross_reference: CiteXplore:11061612
database_cross_reference: CiteXplore:11088063
database_cross_reference: CiteXplore:11122828
database_cross_reference: CiteXplore:11132538
database_cross_reference: CiteXplore:11142482
database_cross_reference: CiteXplore:11221019
database_cross_reference: CiteXplore:11374818
database_cross_reference: CiteXplore:11489002
database_cross_reference: CiteXplore:11504793
database_cross_reference: CiteXplore:11510027
database_cross_reference: CiteXplore:11585734
database_cross_reference: CiteXplore:11595724
database_cross_reference: CiteXplore:11807603
database_cross_reference: CiteXplore:11859947
database_cross_reference: CiteXplore:11901308
database_cross_reference: CiteXplore:12057041
database_cross_reference: CiteXplore:12057046
database_cross_reference: CiteXplore:12057157
database_cross_reference: CiteXplore:12115355
database_cross_reference: CiteXplore:12142097
database_cross_reference: CiteXplore:12571808
database_cross_reference: CiteXplore:12722678
database_cross_reference: CiteXplore:12722691
database_cross_reference: CiteXplore:12743987
database_cross_reference: CiteXplore:12761494
database_cross_reference: CiteXplore:12798170
database_cross_reference: CiteXplore:12917815
database_cross_reference: CiteXplore:12954073
database_cross_reference: CiteXplore:14606642
database_cross_reference: CiteXplore:14653877
database_cross_reference: CiteXplore:14720338
database_cross_reference: CiteXplore:15131028
database_cross_reference: CiteXplore:15160243
database_cross_reference: CiteXplore:15221904
database_cross_reference: CiteXplore:15282439
database_cross_reference: CiteXplore:15297392
database_cross_reference: CiteXplore:15542781
database_cross_reference: CiteXplore:15637766
database_cross_reference: CiteXplore:15744590
database_cross_reference: CiteXplore:16001951
database_cross_reference: CiteXplore:16041610
database_cross_reference: CiteXplore:16080557
database_cross_reference: CiteXplore:16143373
database_cross_reference: CiteXplore:16149285
database_cross_reference: CiteXplore:16317298
database_cross_reference: CiteXplore:16500746
database_cross_reference: CiteXplore:16555971
database_cross_reference: CiteXplore:16584929
database_cross_reference: CiteXplore:16807461
database_cross_reference: CiteXplore:16807463
database_cross_reference: CiteXplore:16894289

geroprotector
type: Class
subclass of: CHEBI_50267
definition: Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
imported from: chebi.owl
database_cross_reference: PMID:23372317
database_cross_reference: PMID:28580190
database_cross_reference: PMID:30885572
database_cross_reference: PMID:33144142
database_cross_reference: PMID:33973253
database_cross_reference: PMID:34606237
database_cross_reference: Wikipedia:Geroprotector
has_obo_namespace: chebi_ontology
has_related_synonym: anti-aging agent
has_related_synonym: anti-aging agents
has_related_synonym: anti-aging drug
has_related_synonym: anti-aging drugs
has_related_synonym: geroprotective agent
has_related_synonym: geroprotective agents
has_related_synonym: geroprotectors
id: CHEBI:176497
in subset: 3 STAR

alkylaminium
type: Class
subclass of: CHEBI_65296
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alkylamine
definition: A primary ammonium ion obtained by protonation of the amino goup of any alkylamine; major species at pH 7.3.
imported from: chebi.owl
charge: +1
formula: H3NR
mass: 17.031
monoisotopicmass: 17.02655
smiles: [NH3+][*]
has_alternative_id: CHEBI:66885
database_cross_reference: MetaCyc:Alkylamines
database_cross_reference: PMID:9989229
has_obo_namespace: chebi_ontology
has_related_synonym: alkylamine cation
has_related_synonym: alkylaminium cation
has_related_synonym: alkylaminium(1+)
has_related_synonym: an alkylamine
id: CHEBI:17664
in subset: 3 STAR

vitamin B9
type: Class
subclass of: CHEBI_75769
definition: Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin.
imported from: chebi.owl
has exact synonym: vitamin B9
has_obo_namespace: chebi_ontology
has_related_synonym: folate vitamer
has_related_synonym: folate vitamers
has_related_synonym: vitamin B-9
has_related_synonym: vitamin B9 vitamer
has_related_synonym: vitamin B9 vitamers
has_related_synonym: vitamins B9
id: CHEBI:176842
in subset: 3 STAR

chloramphenicol
type: Class
subclass of: diol
subclass of: C-nitro compound
subclass of: CHEBI_36683
subclass of: CHEBI_37622
definition: An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.
definition source: Reference: PMID: 23148581
imported from: chebi.owl
charge: 0
formula: C11H12Cl2N2O5
inchikey: WIIZWVCIJKGZOK-RKDXNWHRSA-N
mass: 323.130
monoisotopicmass: 322.01233
has_alternative_id: CHEBI:13965
has_alternative_id: CHEBI:23106
has_alternative_id: CHEBI:23108
has_alternative_id: CHEBI:3603
has_alternative_id: CHEBI:47327
database_cross_reference: Beilstein:2225532
database_cross_reference: CAS:56-75-7
database_cross_reference: Chemspider:5744
database_cross_reference: DrugBank:DB00446
database_cross_reference: Drug_Central:589
database_cross_reference: HMDB:HMDB0014589
database_cross_reference: KEGG:C00918
database_cross_reference: KEGG:D00104
database_cross_reference: LINCS:LSM-5256
database_cross_reference: MetaCyc:CHLORAMPHENICOL
database_cross_reference: PDBeChem:CLM
database_cross_reference: PMID:11468347
database_cross_reference: PMID:12217690
database_cross_reference: PMID:16659995
database_cross_reference: PMID:16897441
database_cross_reference: PMID:17217404
database_cross_reference: PMID:17692887
database_cross_reference: PMID:17963326
database_cross_reference: PMID:18559535
database_cross_reference: PMID:18657290
database_cross_reference: PMID:18794387
database_cross_reference: PMID:23142491
database_cross_reference: PMID:23317719
database_cross_reference: PMID:23395526
database_cross_reference: PMID:23494278
database_cross_reference: PMID:23512826
database_cross_reference: PMID:23698443
database_cross_reference: PMID:657786
database_cross_reference: PMID:6653106
database_cross_reference: PMID:7040026
database_cross_reference: Patent:GB795131
database_cross_reference: Patent:GB796901
database_cross_reference: Patent:US2483871
database_cross_reference: Patent:US2483884
database_cross_reference: Patent:US2483892
database_cross_reference: Patent:US2839577
database_cross_reference: Pesticides:chloramphenicol
database_cross_reference: VSDB:1835
database_cross_reference: Wikipedia:Chloramphenicol
has exact synonym: 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
has exact synonym: CHLORAMPHENICOL
has exact synonym: Chloramphenicol
has exact synonym: chloramphenicol
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-chloramphenicol
has_related_synonym: Amphicol
has_related_synonym: Chloramex
has_related_synonym: Chlorocid
has_related_synonym: Chlorocol
has_related_synonym: Chloromycetin
has_related_synonym: D-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide
has_related_synonym: D-(-)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol
has_related_synonym: Econochlor
has_related_synonym: Fenicol
has_related_synonym: Globenicol
has_related_synonym: Halomycetin
has_related_synonym: Oleomycetin
has_related_synonym: Sificetina
has_related_synonym: chloramphenicol
has_related_synonym: chloramphenicolum
has_related_synonym: chlornitromycin
has_related_synonym: cloramfenicol

methanol
type: Class
subclass of: volatile organic compound
subclass of: primary alcohol
subclass of: CHEBI_50584
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: Mycoplasma genitalium metabolite
subclass of: Restriction
  on property: has role
  some values from: fuel
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48360
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_52090
definition: The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
imported from: chebi.owl
charge: 0
formula: CH4O
inchi: InChI=1S/CH4O/c1-2/h2H,1H3
inchikey: OKKJLVBELUTLKV-UHFFFAOYSA-N
mass: 32.04186
monoisotopicmass: 32.02621
smiles: CO
has_alternative_id: CHEBI:14588
has_alternative_id: CHEBI:25227
has_alternative_id: CHEBI:44080
has_alternative_id: CHEBI:44553
has_alternative_id: CHEBI:6816
database_cross_reference: Beilstein:1098229
database_cross_reference: CAS:67-56-1
database_cross_reference: Gmelin:449
database_cross_reference: HMDB:HMDB0001875
database_cross_reference: KEGG:C00132
database_cross_reference: KEGG:D02309
database_cross_reference: MetaCyc:METOH
database_cross_reference: PDBeChem:MOH
database_cross_reference: PMID:11141607
database_cross_reference: PMID:11430978
database_cross_reference: PMID:11489599
database_cross_reference: PMID:11680737
database_cross_reference: PMID:11684179
database_cross_reference: PMID:14012711
database_cross_reference: PMID:14678513
database_cross_reference: PMID:14760634
database_cross_reference: PMID:15172721
database_cross_reference: PMID:15906011
database_cross_reference: PMID:16705261
database_cross_reference: PMID:17451998
database_cross_reference: PMID:17733096
database_cross_reference: PMID:19064074
database_cross_reference: PMID:19850112
database_cross_reference: PMID:20314698
database_cross_reference: Reaxys:1098229
database_cross_reference: UM-BBD_compID:c0132
database_cross_reference: Wikipedia:Methanol
has exact synonym: METHANOL
has exact synonym: Methanol
has exact synonym: methanol
has_obo_namespace: chebi_ontology
has_related_synonym: CH3OH
has_related_synonym: MeOH
has_related_synonym: Methyl alcohol
has_related_synonym: Methylalkohol
has_related_synonym: carbinol
has_related_synonym: spirit of wood
has_related_synonym: wood alcohol
has_related_synonym: wood naphtha
has_related_synonym: wood spirit
id: CHEBI:17790
in subset: 3 STAR

organohalogen compound
type: Class
subclass of: heteroorganic entity
subclass of: CHEBI_37578
definition: A compound containing at least one carbon-halogen bond (where X is a halogen atom).
imported from: chebi.owl
charge: 0
formula: RX
smiles: **
has_alternative_id: CHEBI:13444
has_alternative_id: CHEBI:36684
has_alternative_id: CHEBI:8767
database_cross_reference: KEGG:C01322
database_cross_reference: MetaCyc:Organohalogen-Compounds
has_obo_namespace: chebi_ontology
has_related_synonym: RX
has_related_synonym: organic halide
has_related_synonym: organic halides
has_related_synonym: organohalogen compounds
id: CHEBI:17792
in subset: 3 STAR

serine
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: hydroxymethyl group
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: serinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: serinium
subclass of: Restriction
  on property: is tautomer of
  some values from: serine zwitterion
definition: An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)
inchikey: MTCFGRXMJLQNBG-UHFFFAOYSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: NC(CO)C(O)=O
has_alternative_id: CHEBI:15081
has_alternative_id: CHEBI:26648
has_alternative_id: CHEBI:9116
database_cross_reference: Beilstein:1721402
database_cross_reference: CAS:302-84-1
database_cross_reference: Gmelin:26429
database_cross_reference: KEGG:C00716
database_cross_reference: KNApSAcK:C00001393
database_cross_reference: Reaxys:1721402
database_cross_reference: Wikipedia:Serine
has exact synonym: Serine
has exact synonym: serine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-3-hydroxypropionic acid
has_related_synonym: 2-amino-3-hydroxypropanoic acid
has_related_synonym: 3-Hydroxyalanine
has_related_synonym: Serin
id: CHEBI:17822
in subset: 3 STAR

propan-2-ol
type: Class
subclass of: secondary fatty alcohol
subclass of: secondary alcohol
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48356
definition: A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
imported from: chebi.owl
charge: 0
formula: C3H8O
inchi: InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
inchikey: KFZMGEQAYNKOFK-UHFFFAOYSA-N
mass: 60.09502
monoisotopicmass: 60.05751
smiles: CC(C)O
has_alternative_id: CHEBI:14897
has_alternative_id: CHEBI:26280
has_alternative_id: CHEBI:43588
has_alternative_id: CHEBI:8467
database_cross_reference: Beilstein:635639
database_cross_reference: CAS:67-63-0
database_cross_reference: DrugBank:DB04402
database_cross_reference: Drug_Central:4215
database_cross_reference: Gmelin:1464
database_cross_reference: HMDB:HMDB0000863
database_cross_reference: KEGG:C01845
database_cross_reference: KEGG:D00137
database_cross_reference: KNApSAcK:C00048438
database_cross_reference: MetaCyc:ISO-PROPANOL
database_cross_reference: PDBeChem:IPA
database_cross_reference: PMID:24524727
database_cross_reference: PMID:24653974
database_cross_reference: Reaxys:635639
database_cross_reference: UM-BBD_compID:c0519
database_cross_reference: Wikipedia:Isopropyl_Alcohol
database_cross_reference: YMDB:YMDB01718
has exact synonym: Propan-2-ol
has exact synonym: propan-2-ol
has_obo_namespace: chebi_ontology
has_related_synonym: 1-methylethanol
has_related_synonym: 1-methylethyl alcohol
has_related_synonym: 2-Propanol
has_related_synonym: 2-hydroxypropane
has_related_synonym: IPA
has_related_synonym: ISOPROPYL ALCOHOL
has_related_synonym: Isopropanol
has_related_synonym: Isopropyl alcohol
has_related_synonym: Isopropylalkohol
has_related_synonym: i-Propylalkohol
has_related_synonym: i-propanol
has_related_synonym: isopropyl alcohol
has_related_synonym: sec-propanol
id: CHEBI:17824
in subset: 3 STAR

hydrogen chloride
type: Class
subclass of: gas molecular entity
subclass of: hydrogen halide
subclass of: chlorine molecular entity
subclass of: CHEBI_37176
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: is conjugate acid of
  some values from: chloride
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_50315
definition: A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
imported from: chebi.owl
charge: 0
formula: ClH
formula: HCl
inchi: InChI=1S/ClH/h1H
inchikey: VEXZGXHMUGYJMC-UHFFFAOYSA-N
mass: 36.46064
monoisotopicmass: 35.97668
smiles: Cl[H]
has_alternative_id: CHEBI:13364
has_alternative_id: CHEBI:24635
has_alternative_id: CHEBI:5590
database_cross_reference: CAS:7647-01-0
database_cross_reference: Drug_Central:4568
database_cross_reference: Gmelin:322
database_cross_reference: HMDB:HMDB0002306
database_cross_reference: KEGG:C01327
database_cross_reference: KEGG:D02057
database_cross_reference: MetaCyc:HCL
database_cross_reference: PMID:15823700
database_cross_reference: PMID:17492841
database_cross_reference: PMID:22804993
database_cross_reference: Reaxys:1098214
database_cross_reference: Wikipedia:HCl
database_cross_reference: Wikipedia:Hydrochloric_acid
has exact synonym: Hydrogen chloride
has exact synonym: chlorane
has exact synonym: chloridohydrogen
has exact synonym: hydrogen chloride
has_obo_namespace: chebi_ontology
has_related_synonym: Chlorwasserstoff
has_related_synonym: HCl
has_related_synonym: Hydrochloride
has_related_synonym: Hydrogenchlorid
has_related_synonym: Wasserstoffchlorid
has_related_synonym: [HCl]
has_related_synonym: chlorure d'hydrogene
has_related_synonym: cloruro de hidrogeno
has_related_synonym: hydrochloric acid
id: CHEBI:17883
in subset: 3 STAR

donor
type: Class
subclass of: CHEBI_51086
definition: A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
imported from: chebi.owl
has_alternative_id: CHEBI:14202
has_alternative_id: CHEBI:4697
database_cross_reference: KEGG:C01351
has exact synonym: Donor
has_obo_namespace: chebi_ontology
has_related_synonym: Donator
has_related_synonym: donneur
id: CHEBI:17891
in subset: 3 STAR

L-tyrosine
type: Class
subclass of: L-alpha-amino acid
subclass of: tyrosine
subclass of: CHEBI_73690
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64416
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_46209
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-tyrosinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-tyrosinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-tyrosine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_58315
definition: An optically active form of tyrosine having L-configuration.
imported from: chebi.owl
charge: 0
formula: C9H11NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
inchikey: OUYCCCASQSFEME-QMMMGPOBSA-N
mass: 181.18858
monoisotopicmass: 181.07389
smiles: N[C@@H](Cc1ccc(O)cc1)C(O)=O
has_alternative_id: CHEBI:13181
has_alternative_id: CHEBI:21411
has_alternative_id: CHEBI:46070
has_alternative_id: CHEBI:46161
has_alternative_id: CHEBI:6313
database_cross_reference: Beilstein:392441
database_cross_reference: CAS:60-18-4
database_cross_reference: DrugBank:DB00135
database_cross_reference: Drug_Central:2786
database_cross_reference: ECMDB:ECMDB00158
database_cross_reference: Gmelin:50929
database_cross_reference: HMDB:HMDB0000158
database_cross_reference: KEGG:C00082
database_cross_reference: KEGG:D00022
database_cross_reference: KNApSAcK:C00001397
database_cross_reference: MetaCyc:TYR
database_cross_reference: PDBeChem:TYR
database_cross_reference: PMID:15171683
database_cross_reference: PMID:22360849
database_cross_reference: PMID:22402312
database_cross_reference: Reaxys:392441
database_cross_reference: UM-BBD_compID:c0234
database_cross_reference: Wikipedia:Tyrosine
database_cross_reference: YMDB:YMDB00364
has exact synonym: L-Tyrosine
has exact synonym: L-tyrosine
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-alpha-amino-p-hydroxyhydrocinnamic acid
has_related_synonym: (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
has_related_synonym: (S)-(-)-Tyrosine
has_related_synonym: (S)-2-Amino-3-(p-hydroxyphenyl)propionic acid
has_related_synonym: (S)-3-(p-Hydroxyphenyl)alanine
has_related_synonym: (S)-Tyrosine
has_related_synonym: (S)-alpha-amino-4-hydroxybenzenepropanoic acid
has_related_synonym: 4-hydroxy-L-phenylalanine
has_related_synonym: L-Tyrosin
has_related_synonym: TYROSINE
has_related_synonym: Tyr
has_related_synonym: Tyrosine
has_related_synonym: Y
id: CHEBI:17895
in subset: 3 STAR

butyrate
type: Class
subclass of: CHEBI_78115
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: CHEBI_61115
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: butyric acid
definition: A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C4H7O2
inchi: InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1
inchikey: FERIUCNNQQJTOY-UHFFFAOYSA-M
mass: 87.09718
monoisotopicmass: 87.04515
smiles: CCCC([O-])=O
has_alternative_id: CHEBI:13924
has_alternative_id: CHEBI:22946
database_cross_reference: Beilstein:3601060
database_cross_reference: CAS:461-55-2
database_cross_reference: Gmelin:324289
database_cross_reference: KEGG:C00246
database_cross_reference: MetaCyc:BUTYRIC_ACID
database_cross_reference: PMID:17190852
database_cross_reference: PMID:7496326
database_cross_reference: Reaxys:3601060
database_cross_reference: UM-BBD_compID:c0035
has exact synonym: butanoate
has exact synonym: butyrate
has_obo_namespace: chebi_ontology
has_related_synonym: 1-butanoate
has_related_synonym: 1-butyrate
has_related_synonym: 1-propanecarboxylate
has_related_synonym: CH3-[CH2]2-COO(-)
has_related_synonym: butanate
has_related_synonym: butanoate
has_related_synonym: butanoic acid, ion(1-)
has_related_synonym: n-butanoate
has_related_synonym: n-butyrate
has_related_synonym: propanecarboxylate
has_related_synonym: propylformate
id: CHEBI:17968
in subset: 3 STAR

benzyl alcohol
type: Class
subclass of: benzyl alcohols
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: CHEBI_46787
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48318
definition: An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.
imported from: chebi.owl
charge: 0
formula: C7H8O
inchi: InChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2
inchikey: WVDDGKGOMKODPV-UHFFFAOYSA-N
mass: 108.13782
monoisotopicmass: 108.05751
smiles: OCc1ccccc1
has_alternative_id: CHEBI:13888
has_alternative_id: CHEBI:22742
has_alternative_id: CHEBI:3053
database_cross_reference: Beilstein:878307
database_cross_reference: CAS:100-51-6
database_cross_reference: Drug_Central:334
database_cross_reference: Gmelin:26514
database_cross_reference: HMDB:HMDB0003119
database_cross_reference: KEGG:C00556
database_cross_reference: KEGG:C03485
database_cross_reference: KEGG:D00077
database_cross_reference: KNApSAcK:C00029811
database_cross_reference: MetaCyc:BENZYL-ALCOHOL
database_cross_reference: PMID:11766131
database_cross_reference: PMID:21557223
database_cross_reference: PMID:22036973
database_cross_reference: Reaxys:878307
database_cross_reference: UM-BBD_compID:c0278
database_cross_reference: Wikipedia:Benzyl_Alcohol
has exact synonym: Benzyl alcohol
has exact synonym: benzyl alcohol
has exact synonym: phenylmethanol
has_obo_namespace: chebi_ontology
has_related_synonym: (hydroxymethyl)benzene
has_related_synonym: Aromatic alcohol
has_related_synonym: Benzenemethanol
has_related_synonym: Benzylalkohol
has_related_synonym: Hydroxymethylbenzene
has_related_synonym: Phenylcarbinol
has_related_synonym: Phenylmethanol
has_related_synonym: alcoholum benzylicum
has_related_synonym: alcool benzylique
has_related_synonym: alpha-Hydroxytoluene
has_related_synonym: alpha-toluenol
has_related_synonym: benzenecarbinol
has_related_synonym: benzylic alcohol
has_related_synonym: phenylmethyl alcohol
id: CHEBI:17987
in subset: 3 STAR

chloride
type: Class
subclass of: halide anion
subclass of: monoatomic chlorine
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogen chloride
definition: A halide anion formed when chlorine picks up an electron to form an an anion.
imported from: chebi.owl
charge: -1
formula: Cl
inchi: InChI=1S/ClH/h1H/p-1
inchikey: VEXZGXHMUGYJMC-UHFFFAOYSA-M
mass: 35.45270
monoisotopicmass: 34.96940
smiles: [Cl-]
has_alternative_id: CHEBI:13291
has_alternative_id: CHEBI:13970
has_alternative_id: CHEBI:3616
has_alternative_id: CHEBI:3731
has_alternative_id: CHEBI:48804
database_cross_reference: Beilstein:3587171
database_cross_reference: CAS:16887-00-6
database_cross_reference: Gmelin:14910
database_cross_reference: KEGG:C00115
database_cross_reference: KEGG:C00698
database_cross_reference: PDBeChem:CL
database_cross_reference: UM-BBD_compID:c0884
has exact synonym: Chloride
has exact synonym: chloride
has exact synonym: chloride(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: CHLORIDE ION
has_related_synonym: Chloride ion
has_related_synonym: Chloride(1-)
has_related_synonym: Chlorine anion
has_related_synonym: Cl(-)
has_related_synonym: Cl-
id: CHEBI:17996
in subset: 3 STAR

L-lysine
type: Class
subclass of: L-alpha-amino acid
subclass of: aspartate family amino acid
subclass of: lysine
subclass of: CHEBI_83813
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: anticonvulsant
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-lysinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-lysinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysine
subclass of: Restriction
  on property: is tautomer of
  some values from: L-lysine zwitterion
definition: An L-alpha-amino acid; the L-isomer of lysine.
imported from: chebi.owl
charge: 0
formula: C6H14N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1
inchikey: KDXKERNSBIXSRK-YFKPBYRVSA-N
mass: 146.18764
monoisotopicmass: 146.10553
smiles: NCCCC[C@H](N)C(O)=O
has_alternative_id: CHEBI:13135
has_alternative_id: CHEBI:21351
has_alternative_id: CHEBI:43950
has_alternative_id: CHEBI:6264
database_cross_reference: Beilstein:1722531
database_cross_reference: CAS:56-87-1
database_cross_reference: DrugBank:DB00123
database_cross_reference: Drug_Central:1622
database_cross_reference: ECMDB:ECMDB00182
database_cross_reference: Gmelin:364182
database_cross_reference: HMDB:HMDB0000182
database_cross_reference: KEGG:C00047
database_cross_reference: KEGG:D02304
database_cross_reference: KNApSAcK:C00001378
database_cross_reference: MetaCyc:LYS
database_cross_reference: PMID:10930630
database_cross_reference: PMID:16901854
database_cross_reference: PMID:17051348
database_cross_reference: PMID:17979222
database_cross_reference: PMID:22019452
database_cross_reference: PMID:22064742
database_cross_reference: PMID:22575419
database_cross_reference: PMID:22735334
database_cross_reference: PMID:23167968
database_cross_reference: PMID:23325920
database_cross_reference: PMID:23722415
database_cross_reference: PMID:24064214
database_cross_reference: PMID:24831709
database_cross_reference: PMID:25108762
database_cross_reference: PMID:8070089
database_cross_reference: PMID:8587651
database_cross_reference: Reaxys:1722531
database_cross_reference: Wikipedia:Lysine
database_cross_reference: YMDB:YMDB00330
has exact synonym: (2S)-2,6-diaminohexanoic acid
has exact synonym: L-Lysine
has exact synonym: L-lysine
has_obo_namespace: chebi_ontology
has_related_synonym: (S)-2,6-diaminohexanoic acid
has_related_synonym: (S)-alpha,epsilon-diaminocaproic acid
has_related_synonym: (S)-lysine
has_related_synonym: 6-ammonio-L-norleucine
has_related_synonym: K
has_related_synonym: L-2,6-Diaminocaproic acid
has_related_synonym: L-Lysin
has_related_synonym: Lys
has_related_synonym: Lysine acid
has_related_synonym: lysina
has_related_synonym: lysine
has_related_synonym: lysinum
id: CHEBI:18019
in subset: 3 STAR

1,2,4-triazole-3-carboxamide
type: Class
subclass of: primary carboxamide
subclass of: monocarboxylic acid amide
subclass of: CHEBI_35727
subclass of: CHEBI_62733
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49103
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84087
definition: A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin.
imported from: chebi.owl
charge: 0
formula: C3H4N4O
inchi: InChI=1S/C3H4N4O/c4-2(8)3-5-1-6-7-3/h1H,(H2,4,8)(H,5,6,7)
inchikey: ZEWJFUNFEABPGL-UHFFFAOYSA-N
mass: 112.092
monoisotopicmass: 112.03851
smiles: NC(=O)C1=NNC=N1
database_cross_reference: CAS:3641-08-5
database_cross_reference: Chemspider:58634
database_cross_reference: HMDB:HMDB0244869
database_cross_reference: PMID:1368697
database_cross_reference: PMID:1368721
database_cross_reference: PMID:17845853
database_cross_reference: PMID:21202621
database_cross_reference: PMID:212973
database_cross_reference: PMID:2737800
database_cross_reference: PMID:6660848
database_cross_reference: Reaxys:775120
has exact synonym: 1H-1,2,4-triazole-3-carboxamide
has_obo_namespace: chebi_ontology
has_related_synonym: 3-(aminocarbonyl)-1H-1,2,4-triazole
has_related_synonym: 3-carbamoyl-1H-1,2,4-triazole
id: CHEBI:180482
in subset: 3 STAR

lipid
type: Class
subclass of: CHEBI_50860
definition: 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:14517
has_alternative_id: CHEBI:25054
has_alternative_id: CHEBI:6486
database_cross_reference: KEGG COMPOUND:C01356
database_cross_reference: KEGG:C01356
has exact synonym: Lipid
has exact synonym: lipid
has exact synonym: lipids
has_obo_namespace: chebi_ontology
id: CHEBI:18059
in subset: 3 STAR

molnupiravir
type: Class
subclass of: ketoxime
subclass of: CHEBI_35725
subclass of: CHEBI_60783
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50266
subclass of: Restriction
  on property: has functional parent
  some values from: N(4)-hydroxycytidine
definition: A nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19.
imported from: chebi.owl
charge: 0
formula: C13H19N3O7
inchi: InChI=1S/C13H19N3O7/c1-6(2)12(19)22-5-7-9(17)10(18)11(23-7)16-4-3-8(15-21)14-13(16)20/h3-4,6-7,9-11,17-18,21H,5H2,1-2H3,(H,14,15,20)/t7-,9-,10-,11-/m1/s1
inchikey: HTNPEHXGEKVIHG-QCNRFFRDSA-N
mass: 329.309
monoisotopicmass: 329.12230
database_cross_reference: CAS:2349386-89-4
database_cross_reference: CAS:2492423-29-5
database_cross_reference: Chemspider:84400552
database_cross_reference: KEGG:D11943
database_cross_reference: PMCID:PMC8461366
database_cross_reference: PMID:31645453
database_cross_reference: PMID:31910262
database_cross_reference: PMID:31945316
database_cross_reference: PMID:32253226
database_cross_reference: PMID:32503814
database_cross_reference: PMID:32714193
database_cross_reference: PMID:33030468
database_cross_reference: PMID:33273742
database_cross_reference: PMID:33290476
database_cross_reference: PMID:33561864
database_cross_reference: PMID:33588727
database_cross_reference: PMID:33649113
database_cross_reference: PMID:33664631
database_cross_reference: PMID:33863887
database_cross_reference: PMID:33902254
database_cross_reference: PMID:33961695
database_cross_reference: PMID:33989635
database_cross_reference: PMID:34056192
database_cross_reference: PMID:34118236
database_cross_reference: PMID:34244768
database_cross_reference: PMID:34271264
database_cross_reference: PMID:34337170
database_cross_reference: PMID:34381216
database_cross_reference: PMID:34425873
database_cross_reference: PMID:34509661
database_cross_reference: PMID:34518697
database_cross_reference: PMID:34571361
database_cross_reference: Wikipedia:Molnupiravir
has exact synonym: N-hydroxy-5'-O-(2-methylpropanoyl)-3,4-dihydrocytidine
has_obo_namespace: chebi_ontology
has_related_synonym: EIDD 1931 5'-isopropylester
has_related_synonym: EIDD 2801
has_related_synonym: EIDD-2801
has_related_synonym: MK-4482
has_related_synonym: N(4)-hydroxycytidine 5'-isopropylester
has_related_synonym: beta-D-N(4)-hydroxycytidine-5'-isopropyl ester
has_related_synonym: molnupiravir
has_related_synonym: molnupiravirum
has_related_synonym: {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}methyl 2-methylpropanoate
id: CHEBI:180653
in subset: 3 STAR

N(4)-hydroxycytidine
type: Class
subclass of: ketoxime
subclass of: CHEBI_60783
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49103
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76967
subclass of: Restriction
  on property: has functional parent
  some values from: cytidine
definition: A nucleoside analogue that is cytidine which carries a hydroxy group at the N(4)-positon. It has broad-spectrum antiviral activity against influenza, SARS-CoV , SARS-CoV-2 and MERS-CoV.
imported from: chebi.owl
charge: 0
formula: C9H13N3O6
inchi: InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1
inchikey: XCUAIINAJCDIPM-XVFCMESISA-N
mass: 259.218
monoisotopicmass: 259.08044
database_cross_reference: CAS:3258-02-4
database_cross_reference: Chemspider:170635
database_cross_reference: DrugBank:DB15660
database_cross_reference: PMID:31494195
database_cross_reference: PMID:31578288
database_cross_reference: PMID:31645453
database_cross_reference: PMID:32253226
database_cross_reference: PMID:33290476
database_cross_reference: PMID:33327924
database_cross_reference: PMID:33649113
database_cross_reference: PMID:33807492
database_cross_reference: PMID:33989635
database_cross_reference: PMID:34186107
database_cross_reference: PMID:34357881
database_cross_reference: PMID:34381216
database_cross_reference: PMID:34503974
database_cross_reference: PMID:34509661
has exact synonym: N(4)-hydroxycytidine
has exact synonym: N-hydroxy-3,4-dihydrocytidine
has_obo_namespace: chebi_ontology
has_related_synonym: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one
has_related_synonym: 4-N-hydroxycytidine
has_related_synonym: 4-oxime uridine
has_related_synonym: EIDD 1931
has_related_synonym: EIDD-1931
has_related_synonym: N-hydroxycytidine
has_related_synonym: NHC
has_related_synonym: beta-D-N(4)-hydroxycytidine
id: CHEBI:180654
in subset: 3 STAR

Apicidin C
type: Class
subclass of: oligopeptide
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000008481
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 17868033
imported from: chebi.owl
charge: 0
formula: C33H47N5O6
inchi: InChI=1S/C33H47N5O6/c1-5-23(39)13-7-6-8-15-25-30(40)35-26(19-22-20-38(44-4)27-16-10-9-14-24(22)27)31(41)36-29(21(2)3)33(43)37-18-12-11-17-28(37)32(42)34-25/h9-10,14,16,20-21,25-26,28-29H,5-8,11-13,15,17-19H2,1-4H3,(H,34,42)(H,35,40)(H,36,41)/t25-,26-,28+,29-/m0/s1
inchikey: GWLHFNKLJRZBAI-KGKLHAENSA-N
mass: 609.768
monoisotopicmass: 609.35263
database_cross_reference: Chemspider:8049363
has exact synonym: (3S,6S,9S,12R)-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-3-propan-2-yl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
has_obo_namespace: chebi_ontology
id: CHEBI:180988
in subset: 2 STAR

hydrogen halide
type: Class
subclass of: hydracid
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
imported from: chebi.owl
charge: 0
formula: HX
mass: 1.008
monoisotopicmass: 1.00783
smiles: [F,Cl,Br,I]
has_alternative_id: CHEBI:13368
has_alternative_id: CHEBI:37140
has_alternative_id: CHEBI:5599
has exact synonym: hydrogen halide
has exact synonym: hydrogen halides
has_obo_namespace: chebi_ontology
has_related_synonym: HX
has_related_synonym: hydrogen halides
id: CHEBI:18140
in subset: 3 STAR

polysaccharide
type: Class
subclass of: carbohydrate
subclass of: glycan
subclass of: biomacromolecule
definition: A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.
imported from: chebi.owl
has_alternative_id: CHEBI:14864
has_alternative_id: CHEBI:26205
has_alternative_id: CHEBI:8322
database_cross_reference: KEGG:C00420
has exact synonym: Polysaccharide
has exact synonym: polysaccharides
has_obo_namespace: chebi_ontology
has_related_synonym: Glycan
has_related_synonym: Glycane
has_related_synonym: Glykan
has_related_synonym: Glykane
has_related_synonym: glycans
has_related_synonym: polisacarido
has_related_synonym: polisacaridos
id: CHEBI:18154
in subset: 3 STAR

tyrosine
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: aromatic amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50336
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: has functional parent
  some values from: propionic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tyrosinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: tyrosinium
definition: An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.
imported from: chebi.owl
charge: 0
formula: C9H11NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)
inchikey: OUYCCCASQSFEME-UHFFFAOYSA-N
mass: 181.18858
monoisotopicmass: 181.07389
smiles: NC(Cc1ccc(O)cc1)C(O)=O
has_alternative_id: CHEBI:15277
has_alternative_id: CHEBI:27176
has_alternative_id: CHEBI:9800
database_cross_reference: Beilstein:515881
database_cross_reference: CAS:55520-40-6
database_cross_reference: CAS:556-03-6
database_cross_reference: Gmelin:27744
database_cross_reference: KEGG:C01536
database_cross_reference: KNApSAcK:C00001397
database_cross_reference: PMID:17190852
database_cross_reference: Reaxys:515881
has exact synonym: Tyrosine
has exact synonym: tyrosine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-3-(p-hydroxyphenyl)propionic acid
has_related_synonym: 2-amino-3-(4-hydroxyphenyl)propanoic acid
has_related_synonym: 3-(p-Hydroxyphenyl)alanine
has_related_synonym: Tyr
has_related_synonym: Tyrosin
has_related_synonym: Y
has_related_synonym: tirosina
id: CHEBI:18186
in subset: 3 STAR

glutamic acid
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50329
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glutamate(1-)
definition: An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.
imported from: chebi.owl
charge: 0
formula: C5H9NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)
inchikey: WHUUTDBJXJRKMK-UHFFFAOYSA-N
mass: 147.12930
monoisotopicmass: 147.05316
smiles: NC(CCC(O)=O)C(O)=O
has_alternative_id: CHEBI:24314
has_alternative_id: CHEBI:5431
database_cross_reference: Beilstein:1723799
database_cross_reference: CAS:617-65-2
database_cross_reference: Gmelin:101971
database_cross_reference: KEGG:C00302
database_cross_reference: KEGG:D04341
database_cross_reference: KNApSAcK:C00001358
database_cross_reference: KNApSAcK:C00019577
database_cross_reference: PMID:15739367
database_cross_reference: PMID:17190852
database_cross_reference: PMID:24616376
database_cross_reference: PMID:24984001
database_cross_reference: Reaxys:1723799
database_cross_reference: Wikipedia:Glutamic_acid
has exact synonym: 2-aminopentanedioic acid
has exact synonym: Glutamic acid
has exact synonym: glutamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Aminoglutaric acid
has_related_synonym: DL-Glutamic acid
has_related_synonym: DL-Glutaminic acid
has_related_synonym: E
has_related_synonym: Glu
has_related_synonym: Glutamate
has_related_synonym: Glutaminic acid
has_related_synonym: Glutaminsaeure
id: CHEBI:18237
in subset: 3 STAR

ribonucleoside
type: Class
subclass of: nucleoside
subclass of: CHEBI_47019
definition: Any nucleoside where the sugar component is D-ribose.
imported from: chebi.owl
charge: 0
formula: C5H9O4R
mass: 133.123
monoisotopicmass: 133.05008
smiles: OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O
has_alternative_id: CHEBI:13014
has_alternative_id: CHEBI:13015
has_alternative_id: CHEBI:13685
has_alternative_id: CHEBI:21085
has_alternative_id: CHEBI:26560
has_alternative_id: CHEBI:4240
has_alternative_id: CHEBI:8844
database_cross_reference: KEGG:C00911
has exact synonym: Ribonucleoside
has_obo_namespace: chebi_ontology
has_related_synonym: a ribonucleoside
has_related_synonym: ribonucleosides
id: CHEBI:18254
in subset: 3 STAR

2'-deoxyribonucleoside
type: Class
subclass of: deoxyribonucleoside
subclass of: CHEBI_47018
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C5H9O3R
mass: 117.123
monoisotopicmass: 117.05517
smiles: OC[C@H]1O[C@@H]([*])C[C@@H]1O
has_alternative_id: CHEBI:1083
has_alternative_id: CHEBI:11394
has_alternative_id: CHEBI:11567
has_alternative_id: CHEBI:11568
has_alternative_id: CHEBI:19259
has_alternative_id: CHEBI:19560
has_alternative_id: CHEBI:4421
database_cross_reference: KEGG COMPOUND:C02269
database_cross_reference: KEGG COMPOUND:C03216
database_cross_reference: KEGG:C02269
database_cross_reference: KEGG:C03216
has_obo_namespace: chebi_ontology
has_related_synonym: 2'-Deoxynucleoside
has_related_synonym: 2'-deoxynucleoside
has_related_synonym: 2'-deoxyribonucleosides
has_related_synonym: 2-Deoxy-D-ribosyl-base
has_related_synonym: Deoxynucleoside
has_related_synonym: a 2'-deoxyribonucleoside
id: CHEBI:18274
in subset: 3 STAR

nucleobase
type: Class
subclass of: CHEBI_38101
definition: That part of DNA or RNA that may be involved in pairing.
imported from: chebi.owl
has_alternative_id: CHEBI:13873
has_alternative_id: CHEBI:25598
has_alternative_id: CHEBI:2995
database_cross_reference: KEGG:C00701
database_cross_reference: Wikipedia:Nucleobase
has_obo_namespace: chebi_ontology
has_related_synonym: Base
has_related_synonym: nucleobases
id: CHEBI:18282
in subset: 3 STAR

alkane
type: Class
subclass of: hydrocarbon
subclass of: aliphatic compound
definition: An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
imported from: chebi.owl
charge: 0
formula: CH3R
mass: 15.035
monoisotopicmass: 15.02348
smiles: C[*]
has_alternative_id: CHEBI:13435
has_alternative_id: CHEBI:22317
has_alternative_id: CHEBI:2576
database_cross_reference: KEGG:C01371
has exact synonym: Alkane
has exact synonym: alkane
has exact synonym: alkanes
has_obo_namespace: chebi_ontology
has_related_synonym: Alkan
has_related_synonym: RH
has_related_synonym: alcane
has_related_synonym: alcanes
has_related_synonym: alcano
has_related_synonym: alcanos
has_related_synonym: an alkane
id: CHEBI:18310
in subset: 3 STAR

phosphate(3-)
type: Class
subclass of: CHEBI_35780
subclass of: CHEBI_79387
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_43474
definition: A phosphate ion that is the conjugate base of hydrogenphosphate.
imported from: chebi.owl
charge: -3
formula: O4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
mass: 94.97136
monoisotopicmass: 94.95507
smiles: [O-]P([O-])([O-])=O
has_alternative_id: CHEBI:14791
has_alternative_id: CHEBI:45024
has_alternative_id: CHEBI:7793
database_cross_reference: Beilstein:3903772
database_cross_reference: CAS:14265-44-2
database_cross_reference: Gmelin:1997
database_cross_reference: KEGG:C00009
database_cross_reference: PDBeChem:PO4
database_cross_reference: Reaxys:3903772
has exact synonym: phosphate
has exact synonym: tetraoxidophosphate(3-)
has exact synonym: tetraoxophosphate(3-)
has exact synonym: tetraoxophosphate(V)
has_obo_namespace: chebi_ontology
has_related_synonym: Orthophosphate
has_related_synonym: PHOSPHATE ION
has_related_synonym: PO4(3-)
has_related_synonym: Phosphate
has_related_synonym: [PO4](3-)
id: CHEBI:18367
in subset: 3 STAR

nitrile
type: Class
subclass of: cyanides
subclass of: Restriction
  on property: has part
  some values from: CHEBI_48819
definition: A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it.
imported from: chebi.owl
charge: 0
formula: CNR
mass: 26.01740
monoisotopicmass: 26.00307
smiles: [*]C#N
has_alternative_id: CHEBI:13212
has_alternative_id: CHEBI:13426
has_alternative_id: CHEBI:13660
has_alternative_id: CHEBI:25547
has_alternative_id: CHEBI:7584
database_cross_reference: KEGG:C00726
has exact synonym: Nitrile
has exact synonym: nitrile
has exact synonym: nitriles
has_obo_namespace: chebi_ontology
has_related_synonym: Nitril
has_related_synonym: R-CN
has_related_synonym: a nitrile
has_related_synonym: nitrilos
id: CHEBI:18379
in subset: 3 STAR

hydrogen cyanide
type: Class
subclass of: hydracid
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64909
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cyanide
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_36856
definition: A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom
imported from: chebi.owl
charge: 0
formula: CHN
inchi: InChI=1S/CHN/c1-2/h1H
inchikey: LELOWRISYMNNSU-UHFFFAOYSA-N
mass: 27.02530
monoisotopicmass: 27.01090
smiles: C#N
has_alternative_id: CHEBI:13362
has_alternative_id: CHEBI:5786
database_cross_reference: CAS:74-90-8
database_cross_reference: HMDB:HMDB0060292
database_cross_reference: KEGG:C01326
database_cross_reference: KNApSAcK:C00007569
database_cross_reference: MetaCyc:HCN
database_cross_reference: PMID:19849830
database_cross_reference: PMID:26700190
database_cross_reference: PMID:26778429
database_cross_reference: PMID:26823582
database_cross_reference: PMID:26940198
database_cross_reference: PMID:27123778
database_cross_reference: Reaxys:1718793
database_cross_reference: Wikipedia:Hydrogen_cyanide
has exact synonym: Hydrogen cyanide
has exact synonym: hydridonitridocarbon
has exact synonym: hydrogen cyanide
has exact synonym: hydrogen(nitridocarbonate)
has exact synonym: methanenitrile
has_obo_namespace: chebi_ontology
has_related_synonym: Blausaeure
has_related_synonym: Cyanwasserstoff
has_related_synonym: HCN
has_related_synonym: [CHN]
has_related_synonym: formonitrile
has_related_synonym: hydrocyanic acid
id: CHEBI:18407
in subset: 3 STAR

delta-lactone
type: Class
subclass of: lactone
definition: A lactone having a six-membered lactone ring.
imported from: chebi.owl
has exact synonym: delta-lactone
has_obo_namespace: chebi_ontology
has_related_synonym: 1,5-lactone
has_related_synonym: 1,5-lactones
has_related_synonym: delta-lactona
has_related_synonym: delta-lactonas
has_related_synonym: delta-lactones
id: CHEBI:18946
in subset: 3 STAR

AZ3451
type: Class
subclass of: secondary carboxamide
subclass of: nitrile
subclass of: benzimidazoles
subclass of: CHEBI_37141
subclass of: CHEBI_38298
subclass of: Restriction
  on property: chemical modulates protein
  some values from: PR_000001662
subclass of: Restriction
  on property: has role
  some values from: autophagy inducer
subclass of: Restriction
  on property: has role
  some values from: PAR2 negative allosteric modulator
subclass of: Restriction
  on property: has role
  some values from: CHEBI_67079
subclass of: Restriction
  on property: has role
  some values from: PAR2 negative allosteric modulator
definition: A member of the class of benzimidazoles that is 1H-benzimidazole substituted by (1S)-1-cyclohexylethyl, 6-bromo-1,3-benzodioxol-5-yl, and 4-(cyanoanilino)acyl groups at positions 1, 2 and 5, respectively. It is an allosteric modulator of protease-activated receptor 2 (IC50 = 23 nM) and exhibits anti-osteoarthritis properties.
definition source: Reference: PMID: 28445455
imported from: chebi.owl
charge: 0
formula: C30H27BrN4O3
inchi: InChI=1S/C30H27BrN4O3/c1-18(20-5-3-2-4-6-20)35-26-12-9-21(30(36)33-22-10-7-19(16-32)8-11-22)13-25(26)34-29(35)23-14-27-28(15-24(23)31)38-17-37-27/h7-15,18,20H,2-6,17H2,1H3,(H,33,36)/t18-/m0/s1
inchikey: FJAOGFGHTPYADT-SFHVURJKSA-N
mass: 571.475
monoisotopicmass: 570.12665
database_cross_reference: CAS:2100284-59-9
database_cross_reference: Chemspider:59053349
database_cross_reference: PDBeChem:8UN
database_cross_reference: PMID:28445455
database_cross_reference: PMID:29457894
database_cross_reference: PMID:29798827
database_cross_reference: PMID:31841119
database_cross_reference: PMID:33242065
database_cross_reference: PMID:34307771
database_cross_reference: PMID:34590836
has exact synonym: 2-(6-bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]-1H-benzimidazole-5-carboxamide
has_obo_namespace: chebi_ontology
has_related_synonym: AZ 3451
has_related_synonym: AZ-3451
id: CHEBI:189647
in subset: 3 STAR

PB28
type: Class
subclass of: piperazines
subclass of: aromatic ether
subclass of: CHEBI_36786
subclass of: Restriction
  on property: chemical modulates protein
  some values from: PR_000011650
subclass of: Restriction
  on property: chemical modulates protein
  some values from: PR_000032038
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: sigma-2 receptor agonist
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
subclass of: Restriction
  on property: has role
  some values from: modulator
definition: A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
definition source: Reference: PMID: 16891467
imported from: chebi.owl
charge: 0
formula: C24H38N2O
inchi: InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3
inchikey: PHRCDWVPTULQMT-UHFFFAOYSA-N
mass: 370.581
monoisotopicmass: 370.29841
database_cross_reference: CAS:172906-90-0
database_cross_reference: Chemspider:8649746
database_cross_reference: PMID:15322732
database_cross_reference: PMID:16687172
database_cross_reference: PMID:16891467
database_cross_reference: PMID:18178434
database_cross_reference: PMID:19200007
database_cross_reference: PMID:19842660
database_cross_reference: PMID:20021355
database_cross_reference: PMID:20077462
database_cross_reference: PMID:21229979
database_cross_reference: PMID:21684636
database_cross_reference: PMID:21744858
database_cross_reference: PMID:22890883
database_cross_reference: PMID:23399765
database_cross_reference: PMID:24697311
database_cross_reference: PMID:25637276
database_cross_reference: PMID:28086830
database_cross_reference: PMID:28764962
database_cross_reference: PMID:29438891
database_cross_reference: PMID:31994091
database_cross_reference: PMID:33052254
database_cross_reference: PMID:33364961
database_cross_reference: PMID:34783163
database_cross_reference: Wikipedia:PB-28
has exact synonym: 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine
has_obo_namespace: chebi_ontology
has_related_synonym: 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine
has_related_synonym: 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine
has_related_synonym: 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine
has_related_synonym: PB 28
has_related_synonym: PB-28
id: CHEBI:189648
in subset: 3 STAR

AC-55541
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical has protein target as agonist
  some values from: PR_000001662
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48705
definition source: Reference: PMID: 18720984
imported from: chebi.owl
charge: 0
formula: C25H20BrN5O3
inchi: InChI=1S/C25H20BrN5O3/c1-15(17-10-7-11-18(26)14-17)28-31-25(34)22(27-23(32)16-8-3-2-4-9-16)21-19-12-5-6-13-20(19)24(33)30-29-21/h2-14,22H,1H3,(H,27,32)(H,30,33)(H,31,34)/b28-15+
inchikey: UCUHFWIFSHROPY-RWPZCVJISA-N
mass: 518.371
monoisotopicmass: 517.07495
database_cross_reference: ChemIDplus:9589606
has exact synonym: N-[2-{(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl}-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl]benzamide
has_obo_namespace: chebi_ontology
has_related_synonym: AC 55541
has_related_synonym: AC55541
id: CHEBI:189649
in subset: 2 STAR

Ternatin 4 (DA3)
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000050270
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 26651998
imported from: chebi.owl
charge: +1
formula: C60H65O34
inchi: InChI=1S/C60H64O34/c61-19-35-44(71)48(75)52(79)57(91-35)86-28-9-3-24(4-10-28)6-12-41(68)84-21-37-46(73)50(77)54(81)59(93-37)89-33-14-25(13-32(43(33)70)88-58-53(80)49(76)45(72)36(92-58)20-83-40(67)11-5-23-1-7-26(62)8-2-23)56-34(17-29-30(64)15-27(63)16-31(29)87-56)90-60-55(82)51(78)47(74)38(94-60)22-85-42(69)18-39(65)66/h1-17,35-38,44-55,57-61,71-82H,18-22H2,(H4-,62,63,64,65,66,67,70)/p+1/b12-6+/t35-,36-,37-,38-,44-,45-,46-,47-,48+,49+,50+,51+,52-,53-,54-,55?,57-,58-,59-,60-/m1/s1
inchikey: LPANCZMXTVCHJO-YHXPGJEVSA-O
mass: 1330.145
monoisotopicmass: 1329.33518
database_cross_reference: ChemIDplus:11981715
has_obo_namespace: chebi_ontology
id: CHEBI:189650
in subset: 2 STAR

dBET6
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical degrades protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical degrades protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: BRD proteins degrader
definition source: Reference: PMID: 29764999
imported from: chebi.owl
charge: 0
formula: C42H45ClN8O7S
inchikey: JGQPZPLJOBHHBK-UFXYQILXSA-N
mass: 841.380
monoisotopicmass: 840.28204
database_cross_reference: ChemIDplus:121427831
has_obo_namespace: chebi_ontology
id: CHEBI:189651
in subset: 2 STAR

MZ1
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical degrades protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical degrades protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: BRD proteins degrader
definition source: Reference: PMID: 26035625
imported from: chebi.owl
charge: 0
formula: C49H60ClN9O8S2
inchikey: PTAMRJLIOCHJMQ-PYNGZGNASA-N
mass: 1002.640
monoisotopicmass: 1001.36948
database_cross_reference: ChemIDplus:122201421
has_obo_namespace: chebi_ontology
id: CHEBI:189652
in subset: 2 STAR

pelabresib
type: Class
subclass of: primary carboxamide
subclass of: organic heterotricyclic compound
subclass of: CHEBI_83403
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004806
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004807
subclass of: Restriction
  on property: has role
  some values from: bromodomain-containing protein 4 inhibitor
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: An organic heterotricyclic compound that is 4H-[1,2]oxazolo[5,4-d][2]benzazepine substituted by methyl, 2-amino-2-oxoethyl, and 4-chlorophenyl groups at positions 1, 4S and 6, respectively. It is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins and exhibits antineoplastic activity.
definition source: Reference: PMID: 26815195
imported from: chebi.owl
charge: 0
formula: C20H16ClN3O2
inchi: InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)/t16-/m0/s1
inchikey: GCWIQUVXWZWCLE-INIZCTEOSA-N
mass: 365.820
monoisotopicmass: 365.09310
database_cross_reference: CAS:1380087-89-7
database_cross_reference: Chemspider:32738784
database_cross_reference: PMID:26815195
database_cross_reference: PMID:27890933
database_cross_reference: PMID:30529073
database_cross_reference: PMID:31729905
database_cross_reference: PMID:32245330
database_cross_reference: PMID:32927276
database_cross_reference: PMID:33509905
database_cross_reference: PMID:33574760
database_cross_reference: PMID:33925695
database_cross_reference: PMID:35114569
database_cross_reference: Wikipedia:CPI-0610
has exact synonym: 2-[(4S)-6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepin-4-yl]acetamide
has_obo_namespace: chebi_ontology
has_related_synonym: 2-((4S)-6-(4-chlorophenyl)-1-methyl-4H-isoxazolo[5,4-d][2]benzazepin-4-yl)acetamide
has_related_synonym: CPI 0610
has_related_synonym: CPI-0610
has_related_synonym: CPI-0610 anhydrous
has_related_synonym: CPI-232
has_related_synonym: CPI0610
has_related_synonym: pelabresib
has_related_synonym: pelabresibum
id: CHEBI:189653
in subset: 3 STAR

4E2RCat
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: GO_0006412
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 21507972
imported from: chebi.owl
charge: 0
formula: C22H14ClNO4S2
inchikey: WOBPZFKXPCYOLU-YBFXNURJSA-N
mass: 455.930
monoisotopicmass: 455.00528
has_obo_namespace: chebi_ontology
id: CHEBI:189654
in subset: 2 STAR

PS3061
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition source: Reference: PMID: 30550790
imported from: chebi.owl
charge: 0
formula: C53H75BrN8O8
inchi: InChI=1S/C53H75BrN8O8/c1-31(2)24-40-50(66)59(10)35(9)53(69)70-46(18-15-23-55)49(65)58-42(26-33(5)6)52(68)60(11)44(27-34(7)8)47(63)57-41(25-32(3)4)51(67)61(12)45(48(64)56-40)28-37-30-62(43-17-14-13-16-39(37)43)29-36-19-21-38(54)22-20-36/h13-14,16-17,19-22,30-35,40-42,44-46H,15,18,24-29H2,1-12H3,(H,56,64)(H,57,63)(H,58,65)
inchikey: YYGUUQZMWURKTR-UHFFFAOYSA-N
mass: 1032.135
monoisotopicmass: 1030.48912
database_cross_reference: ChemIDplus:146047984
has_obo_namespace: chebi_ontology
id: CHEBI:189655
in subset: 2 STAR

4EGI-1
type: Class
subclass of: dichlorobenzene
subclass of: monocarboxylic acid
subclass of: C-nitro compound
subclass of: CHEBI_38418
subclass of: CHEBI_38532
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: GO_0006412
subclass of: Restriction
  on property: has role
  some values from: Translation Initiation Targets
definition source: Reference: PMID: 29116477
imported from: chebi.owl
charge: 0
formula: C18H12Cl2N4O4S
inchikey: KFRKRECSIYXARE-UHFFFAOYSA-N
mass: 451.280
monoisotopicmass: 449.99563
smiles: OC(=O)C(CC1=CC=CC=C1[N+]([O-])=O)=NNC1=NC(=CS1)C1=CC=C(Cl)C(Cl)=C1
database_cross_reference: CAS:315706-13-9
database_cross_reference: PMID:25049413
database_cross_reference: Wikipedia:4EGI-1
has_obo_namespace: chebi_ontology
id: CHEBI:189658
in subset: 2 STAR

PF-06446846
type: Class
subclass of: tertiary carboxamide
subclass of: benzamides
subclass of: piperidines
subclass of: CHEBI_39172
subclass of: CHEBI_46746
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000014208
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.21.61 (kexin) inhibitor
subclass of: Restriction
  on property: has role
  some values from: antilipemic drug
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9.
definition source: Reference: PMID: 28323820
imported from: chebi.owl
charge: 0
formula: C22H20ClN7O
inchi: InChI=1S/C22H20ClN7O/c23-18-5-2-12-25-20(18)29(17-4-1-11-24-14-17)22(31)15-7-9-16(10-8-15)30-21-19(27-28-30)6-3-13-26-21/h2-3,5-10,12-13,17,24H,1,4,11,14H2/t17-/m1/s1
inchikey: FDTXHWQFIXYHCL-QGZVFWFLSA-N
mass: 433.900
monoisotopicmass: 433.14179
database_cross_reference: CAS:1632250-49-7
database_cross_reference: Chemspider:74849329
database_cross_reference: PDBeChem:MVM
database_cross_reference: PMID:28323820
database_cross_reference: PMID:29878763
database_cross_reference: PMID:31160784
database_cross_reference: PMID:31867167
database_cross_reference: PMID:33009412
database_cross_reference: PMID:33801308
database_cross_reference: PMID:34359627
database_cross_reference: Patent:US9227956
has exact synonym: N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide
has exact synonym: PF-06446846
has_obo_namespace: chebi_ontology
has_related_synonym: PF 06446846
has_related_synonym: PF-846
has_related_synonym: PF06446846
id: CHEBI:189659
in subset: 3 STAR

RapaLink-1
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000007532
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000007535
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000007543
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000009668
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68481
definition source: Reference: PMID: 29722158
imported from: chebi.owl
charge: 0
formula: C91H138N12O24
inchikey: QDOGZMBPRITPMZ-PKZGRWOKSA-N
mass: 1784.165
monoisotopicmass: 1782.99469
database_cross_reference: ChemIDplus:137076847
has_obo_namespace: chebi_ontology
id: CHEBI:189661
in subset: 2 STAR

XL413
type: Class
subclass of: benzofuropyrimidine
subclass of: CHEBI_36683
subclass of: CHEBI_38260
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000006606
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50925
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A benzofuropyrimidine that is 3,4-dihydro[1]benzofuro[3,2-d]pyrimidine substituted by (2S)-pyrrolidin-2-yl, oxo and chloro groups at positions 2, 4, and 8, respectively. It is a potent ATP competitive inhibitor of Cdc7 kinase (IC50 = 3.4 nM) and exhibits anticancer properties.
definition source: Reference: PMID: 22560567
imported from: chebi.owl
charge: 0
formula: C14H12ClN3O2
inchi: InChI=1S/C14H12ClN3O2/c15-7-3-4-10-8(6-7)11-12(20-10)14(19)18-13(17-11)9-2-1-5-16-9/h3-4,6,9,16H,1-2,5H2,(H,17,18,19)/t9-/m0/s1
inchikey: JJWLXRKVUJDJKG-VIFPVBQESA-N
mass: 289.720
monoisotopicmass: 289.06180
database_cross_reference: CAS:1169558-38-6
database_cross_reference: Chemspider:28508270
database_cross_reference: DrugBank:DB12357
database_cross_reference: PDBeChem:0SX
database_cross_reference: PMID:22560567
database_cross_reference: PMID:23064647
database_cross_reference: PMID:25412417
database_cross_reference: PMID:26589264
database_cross_reference: PMID:28560864
database_cross_reference: PMID:29713760
database_cross_reference: PMID:30802412
database_cross_reference: PMID:32355159
database_cross_reference: PMID:32521228
database_cross_reference: PMID:34307771
database_cross_reference: Wikipedia:XL-413
has exact synonym: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one
has_obo_namespace: chebi_ontology
has_related_synonym: BMS 863233
has_related_synonym: BMS-863233
has_related_synonym: BMS863233
has_related_synonym: XL 413
has_related_synonym: XL-413
id: CHEBI:189662
in subset: 3 STAR

benzofuropyrimidine
type: Class
subclass of: organic heterotricyclic compound
subclass of: CHEBI_38101
subclass of: CHEBI_38104
definition: An organic heterotricyclic compound in which pyrmidine is ortho-fused to a bicyclic benzofuran ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzofuropyrimidines
id: CHEBI:189664
in subset: 3 STAR

EC 3.4.21.61 (kexin) inhibitor
type: Class
subclass of: CHEBI 5924
definition: An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61).
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: EC 3.4.21.61 (kexin) inhibitors
has_related_synonym: EC 3.4.21.61 inhibitor
has_related_synonym: EC 3.4.21.61 inhibitors
has_related_synonym: Kex 2p proteinase inhibitor
has_related_synonym: Kex 2p proteinase inhibitors
has_related_synonym: Kex2 endopeptidase inhibitor
has_related_synonym: Kex2 endopeptidase inhibitors
has_related_synonym: Kex2 endoprotease inhibitor
has_related_synonym: Kex2 endoprotease inhibitors
has_related_synonym: Kex2 endoproteinase inhibitor
has_related_synonym: Kex2 endoproteinase inhibitors
has_related_synonym: Kex2 protease inhibitor
has_related_synonym: Kex2 protease inhibitors
has_related_synonym: Kex2 proteinase inhibitor
has_related_synonym: Kex2 proteinase inhibitors
has_related_synonym: Kex2-like endoproteinase inhibitor
has_related_synonym: Kex2-like endoproteinase inhibitors
has_related_synonym: Kex2-like precursor protein processing endoprotease inhibitor
has_related_synonym: Kex2-like precursor protein processing endoprotease inhibitors
has_related_synonym: andrenorphin-Gly-generating enzyme inhibitor
has_related_synonym: andrenorphin-Gly-generating enzyme inhibitors
has_related_synonym: endoproteinase Kex2p inhibitor
has_related_synonym: endoproteinase Kex2p inhibitors
has_related_synonym: gene KEX2 dibasic proteinase inhibitor
has_related_synonym: gene KEX2 dibasic proteinase inhibitors
has_related_synonym: kexin inhibitor
has_related_synonym: kexin inhibitors
has_related_synonym: paired-basic endopeptidase inhibitor
has_related_synonym: paired-basic endopeptidase inhibitors
has_related_synonym: prohormone-processing KEX2 proteinase inhibitor
has_related_synonym: prohormone-processing KEX2 proteinase inhibitors
has_related_synonym: prohormone-processing endoprotease inhibitor
has_related_synonym: prohormone-processing endoprotease inhibitors
has_related_synonym: prohormone-processing proteinase inhibitor
has_related_synonym: prohormone-processing proteinase inhibitors
has_related_synonym: proprotein convertase inhibitor
has_related_synonym: proprotein convertase inhibitors
has_related_synonym: protease KEX2 inhibitor
has_related_synonym: protease KEX2 inhibitors
has_related_synonym: proteinase Kex2p inhibitor
has_related_synonym: proteinase Kex2p inhibitors
has_related_synonym: proteinase yscF inhibitor
has_related_synonym: proteinase yscF inhibitors
has_related_synonym: yeast KEX2 protease inhibitor
has_related_synonym: yeast KEX2 protease inhibitors
id: CHEBI:189665
in subset: 3 STAR

PAR2 negative allosteric modulator
type: Class
subclass of: protease-activated receptor-2 antagonist
subclass of: CHEBI_90710
definition: a group of substances that bind to a receptor to change that receptor's response to stimulus.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:189675
in subset: 2 STAR

protease-activated receptor-2 antagonist
type: Class
subclass of: CHEBI_48706
definition: An antagonist at the protease-activated receptor-2.
imported from: chebi.owl
database_cross_reference: PMID:10657317
database_cross_reference: Wikipedia:Protease-activated_receptor_2
has_obo_namespace: chebi_ontology
has_related_synonym: G-protein coupled receptor 11 antagonist
has_related_synonym: G-protein coupled receptor 11 antagonists
has_related_synonym: GPR11 antagonist
has_related_synonym: GPR11 antagonists
has_related_synonym: PAR-2 antagonist
has_related_synonym: PAR-2 antagonists
has_related_synonym: PAR2 antagonist
has_related_synonym: PAR2 antagonists
has_related_synonym: coagulation factor II (thrombin) receptor-like 1 antagonist
has_related_synonym: coagulation factor II (thrombin) receptor-like 1 antagonists
has_related_synonym: protease-activated receptor 2 antagonist
has_related_synonym: protease-activated receptor 2 antagonists
has_related_synonym: protease-activated receptor-2 antagonists
id: CHEBI:189676
in subset: 3 STAR

modulator
type: Class
subclass of: CHEBI_50860
definition: a group of substances that bind to a receptor to change that receptor's response to stimulus
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:189678
in subset: 2 STAR

BRD proteins degrader
type: Class
subclass of: CHEBI_50860
definition: Protein degraders tackle tough drug targets by hijacking a cell's natural system for disposing of spent or misfolded proteins
imported from: chebi.owl
database_cross_reference: PMID:33575085
has_obo_namespace: chebi_ontology
id: CHEBI:189679
in subset: 2 STAR

protein binder
type: Class
subclass of: CHEBI_50860
definition: A binding protein is any protein that acts as an agent to bind two or more molecules together.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:189680
in subset: 2 STAR

mitochondrial ribosomes
type: Class
subclass of: CHEBI_50860
definition: a protein complex that is active in mitochondria and functions as a riboprotein for translating mitochondrial mRNAs encoded in mtDNA
imported from: chebi.owl
database_cross_reference: Wikipedia:1056127308
has_obo_namespace: chebi_ontology
id: CHEBI:189681
in subset: 2 STAR

Translation Initiation Targets
type: Class
subclass of: CHEBI_50860
definition: The target that the mRNA translation initiates
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:189682
in subset: 2 STAR

sigma receptor modulator
type: Class
subclass of: CHEBI_90710
definition: Any receptor modulator acting on sigma receptors.
imported from: chebi.owl
database_cross_reference: Wikipedia:Sigma_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: sigma receptor modulators
has_related_synonym: sigma-receptor modulator
has_related_synonym: sigma-receptor modulators
id: CHEBI:189683
in subset: 3 STAR

sigma-2 receptor agonist
type: Class
subclass of: sigma receptor modulator
definition: A sigma receptor modulator that activates the sigma-2 receptor.
imported from: chebi.owl
database_cross_reference: Wikipedia:Sigma-2_receptor
has_obo_namespace: chebi_ontology
has_related_synonym: sigma 2 receptor agonist
has_related_synonym: sigma 2 receptor agonists
has_related_synonym: sigma-2 receptor agonists
has_related_synonym: sigma2 receptor agonist
has_related_synonym: sigma2 receptor agonists
has_related_synonym: sigma2R agonist
has_related_synonym: sigma2R agonists
id: CHEBI:189684
in subset: 3 STAR

Met-enkephalin zwitterion
type: Class
subclass of: CHEBI_60466
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI 6618
definition: A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino terminus of Met-enkephalin. Major species at pH 7.3.
imported from: chebi.owl
charge: 0
formula: C27H35N5O7S
inchi: InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1
inchikey: YFGBQHOOROIVKG-FKBYEOEOSA-N
mass: 573.670
monoisotopicmass: 573.22572
has exact synonym: N-[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]glycylglycyl-N-[(1S)-1-carboxylato-3-(methylsulfanyl)propyl]-L-phenylalaninamide
has_obo_namespace: chebi_ontology
has_related_synonym: L-Tyr-Gly-Gly-L-Phe-L-Met zwitterion
has_related_synonym: L-tyrosylglycylglycyl-L-phenylalanyl-L-methionine zwitterion
has_related_synonym: M-ENK zwitterion
has_related_synonym: MENK zwitterion
has_related_synonym: Met-enkephalin
has_related_synonym: Tyr-Gly-Gly-Phe-Met zwitterion
has_related_synonym: [Met(5)]-enkephalin zwitterion
has_related_synonym: [Met(5)]enkephalin zwitterion
has_related_synonym: metenkefalin zwitterion
id: CHEBI:189868
in subset: 3 STAR

11alpha-hydroxy steroid
type: Class
subclass of: CHEBI_36841
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: 11alpha-hydroxy steroids
id: CHEBI:19129
in subset: 3 STAR

pyrimidine 2'-deoxyribonucleoside
type: Class
subclass of: 2'-deoxyribonucleoside
subclass of: pyrimidine nucleoside
subclass of: CHEBI_68472
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: pyrimidine 2'-deoxyribonucleosides
id: CHEBI:19255
in subset: 3 STAR

3-oxo-Delta(1) steroid
type: Class
subclass of: CHEBI_47788
subclass of: CHEBI_51689
definition: Any 3-oxo steroid that contains a double bond between positions 1 and 2.
imported from: chebi.owl
charge: 0
formula: C19H27OR
mass: 271.418
monoisotopicmass: 271.20619
has_alternative_id: CHEBI:13603
has_alternative_id: CHEBI:1625
database_cross_reference: KEGG:C02941
database_cross_reference: MetaCyc:3-Oxo-Delta-1-Steroids
has exact synonym: 3-oxo-Delta(1) steroid
has_obo_namespace: chebi_ontology
has_related_synonym: 3-keto-Delta(1) steroid
has_related_synonym: 3-keto-Delta(1) steroids
has_related_synonym: 3-oxo Delta(1)-steroid
has_related_synonym: 3-oxo Delta(1)-steroids
has_related_synonym: 3-oxo-Delta(1) steroids
has_related_synonym: 3-oxo-Delta(1)-steroids
has_related_synonym: 3-oxo-Delta1-steroid
has_related_synonym: 3-oxo-Delta1-steroids
has_related_synonym: a 3-oxo-Delta(1)-steroid
id: CHEBI:20156
in subset: 3 STAR

2-aminopurines
type: Class
subclass of: aminopurine
definition: Any aminopurine having the amino substituent at the 2-position.
imported from: chebi.owl
has exact synonym: 2-aminopurines
has_obo_namespace: chebi_ontology
id: CHEBI:20702
in subset: 3 STAR

ATP synthase inhibitor
type: Class
subclass of: mitochondrial respiratory-chain inhibitor
subclass of: CHEBI_73216
definition: A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:20854
in subset: 3 STAR

C-glycosyl compound
type: Class
subclass of: CHEBI_63161
subclass of: CHEBI_63299
definition: A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a carbon atom, thus creating a C-C bond.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: C-glycoside
has_related_synonym: C-glycosides
has_related_synonym: C-glycosyl compounds
id: CHEBI:20857
in subset: 3 STAR

N-acyl-L-amino acid
type: Class
subclass of: CHEBI_51569
subclass of: Restriction
  on property: is enantiomer of
  some values from: N-acyl-D-amino acid
definition: Any N-acylamino acid having L-configuration.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:21644
in subset: 3 STAR

N-glycosyl compound
type: Class
subclass of: organonitrogen compound
subclass of: CHEBI_63161
subclass of: CHEBI_63299
definition: A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: glycosylamine
has_obo_namespace: chebi_ontology
has_related_synonym: N-glycoside
has_related_synonym: N-glycosides
has_related_synonym: N-glycosyl compounds
has_related_synonym: glycosylamines
id: CHEBI:21731
in subset: 3 STAR

sulfoxide
type: Class
subclass of: organosulfur compound
definition: An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).
imported from: chebi.owl
has_alternative_id: CHEBI:35813
has exact synonym: sulfoxide
has_obo_namespace: chebi_ontology
has_related_synonym: S-oxides
has_related_synonym: sulfoxides
id: CHEBI:22063
in subset: 3 STAR

purine-6-thiol
type: Class
subclass of: CHEBI_82711
subclass of: Restriction
  on property: has role
  some values from: antimetabolite
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has parent hydride
  some values from: 7H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_50667
definition: A thiol that is the tautomer of mercaptopurine.
imported from: chebi.owl
charge: 0
formula: C5H4N4S
inchi: InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
inchikey: GLVAUDGFNGKCSF-UHFFFAOYSA-N
mass: 152.17822
monoisotopicmass: 152.01567
smiles: Sc1ncnc2nc[nH]c12
database_cross_reference: CAS:50-44-2
database_cross_reference: DrugBank:DB01033
database_cross_reference: KEGG:C01756
database_cross_reference: KEGG:C02380
database_cross_reference: PDBeChem:PM6
database_cross_reference: PMID:24211998
database_cross_reference: PMID:24651962
database_cross_reference: PMID:24670805
database_cross_reference: PMID:24774509
database_cross_reference: Reaxys:608595
has exact synonym: 7H-purine-6-thiol
has_obo_namespace: chebi_ontology
has_related_synonym: 1,7-Dihydro-6H-purine-6-thione
has_related_synonym: 3H-Purine-6-thiol
has_related_synonym: 6-MP
has_related_synonym: 6-Thiohypoxanthine
id: CHEBI:2208
in subset: 3 STAR

acaricide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the subclass Acari (mites and ticks).
imported from: chebi.owl
database_cross_reference: Wikipedia:Acaricide
has_obo_namespace: chebi_ontology
has_related_synonym: Akarizid
has_related_synonym: Akarizide
has_related_synonym: acaricides
has_related_synonym: miticide
id: CHEBI:22153
in subset: 3 STAR

acetamides
type: Class
subclass of: CHEBI_37622
definition: Compounds with the general formula RNHC(=O)CH3.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22160
in subset: 3 STAR

acyl group
type: Class
subclass of: organic group
definition: An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
imported from: chebi.owl
has exact synonym: acyl group
has exact synonym: alkanoyl
has_obo_namespace: chebi_ontology
has_related_synonym: acyl groups
has_related_synonym: alkanoyl group
has_related_synonym: groupe acyle
id: CHEBI:22221
in subset: 3 STAR

alkaloid
type: Class
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has role
  some values from: metabolite
definition: Any of basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom (but not excluding those of animal origin). Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. By extension, certain neutral compounds biogenetically related to basic alkaloids are included.
definition: Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.
imported from: chebi.owl
imported from: dron.owl
database_cross_reference: Wikipedia:Alkaloid
has exact synonym: Alkaloid
has exact synonym: alkaloids
has_obo_namespace: chebi_ontology
has_related_synonym: Alkaloide
has_related_synonym: alcaloide
has_related_synonym: alcaloides
id: CHEBI:22315
in subset: 3 STAR

alkyl group
type: Class
subclass of: hydrocarbyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: alkane
definition: A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom.
imported from: chebi.owl
has exact synonym: alkyl group
has exact synonym: alkyl groups
has_obo_namespace: chebi_ontology
has_related_synonym: groupe alkyle
has_related_synonym: grupo alquilo
has_related_synonym: grupos alquilo
id: CHEBI:22323
in subset: 3 STAR

alkylating agent
type: Class
subclass of: mutagen
definition: Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22333
in subset: 3 STAR

amino alcohol
type: Class
subclass of: alcohol
subclass of: CHEBI_50047
definition: An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: amino alcohols
has_related_synonym: aminoalcohol
has_related_synonym: aminoalcohols
id: CHEBI:22478
in subset: 3 STAR

amino cyclitol glycoside
type: Class
subclass of: cyclitol
subclass of: glycoside
imported from: dron.owl
has exact synonym: amino cyclitol glycoside
has_related_synonym: amino cyclitol glycosides
id: CHEBI:22479

amino aldehyde
type: Class
subclass of: aldehyde
definition: Any aldehyde which contains an amino group.
imported from: chebi.owl
database_cross_reference: PMID:17105264
has_obo_namespace: chebi_ontology
id: CHEBI:22492
in subset: 3 STAR

aminodiol
type: Class
subclass of: amino alcohol
subclass of: diol
definition: An amino alcohol having two hydroxy functional groups.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: amino diol
has_related_synonym: amino diols
has_related_synonym: aminodiols
id: CHEBI:22501
in subset: 3 STAR

aminoglycoside antibiotic
type: Class
subclass of: carbohydrate-containing antibiotic
subclass of: CHEBI_47779
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: aminoglycoside antibiotics
id: CHEBI:22507
in subset: 3 STAR

aminopurine
type: Class
subclass of: purines
definition: Any purine having at least one amino substituent.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: aminopurines
id: CHEBI:22527
in subset: 3 STAR

anilines
type: Class
subclass of: benzenes
subclass of: aromatic amine
definition: Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22562
in subset: 3 STAR

anion
type: Class
subclass of: ion
definition: A monoatomic or polyatomic species having one or more elementary charges of the electron.
imported from: chebi.owl
has exact synonym: Anion
has exact synonym: anion
has_obo_namespace: chebi_ontology
has_related_synonym: Anionen
has_related_synonym: aniones
has_related_synonym: anions
id: CHEBI:22563
in subset: 3 STAR

antioxidant
type: Class
subclass of: CHEBI_51086
definition: A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antioxidants
has_related_synonym: antioxydant
has_related_synonym: antoxidant
id: CHEBI:22586
in subset: 3 STAR

antiviral agent
type: Class
subclass of: antimicrobial agent
definition: A substance that destroys or inhibits replication of viruses.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: anti-viral agent
has_related_synonym: anti-viral agents
has_related_synonym: antiviral
has_related_synonym: antiviral agents
has_related_synonym: antivirals
id: CHEBI:22587
in subset: 3 STAR

arenecarboxamide
type: Class
subclass of: monocarboxylic acid amide
subclass of: CHEBI_62733
definition: A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: arenecarboxamides
id: CHEBI:22645
in subset: 3 STAR

asparagine
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: CHEBI_35735
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50330
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: asparaginate
subclass of: Restriction
  on property: is conjugate base of
  some values from: asparaginium
definition: An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 2-amino-2-oxoethyl group.
imported from: chebi.owl
charge: 0
formula: C4H8N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)
inchikey: DCXYFEDJOCDNAF-UHFFFAOYSA-N
mass: 132.11800
monoisotopicmass: 132.05349
smiles: NC(CC(N)=O)C(O)=O
database_cross_reference: Beilstein:1723525
database_cross_reference: CAS:3130-87-8
database_cross_reference: Gmelin:279043
database_cross_reference: KEGG:C16438
database_cross_reference: PMID:22264337
database_cross_reference: PMID:22770225
database_cross_reference: Reaxys:1723525
database_cross_reference: Wikipedia:Asparagine
has exact synonym: asparagine
has_obo_namespace: chebi_ontology
has_related_synonym: 2,4-diamino-4-oxobutanoic acid
has_related_synonym: 2-amino-3-carbamoylpropanoic acid
has_related_synonym: ASN
has_related_synonym: Asn
has_related_synonym: Asparagin
has_related_synonym: DL-Asparagine
has_related_synonym: Hasp
has_related_synonym: N
has_related_synonym: asparagina
id: CHEBI:22653
in subset: 3 STAR

aspartate family amino acid
type: Class
subclass of: L-alpha-amino acid
subclass of: CHEBI_83813
definition: An L-alpha-amino acid which is L-aspartic acid or any of the essential amino acids biosynthesised from it (asparagine, lysine, methionine, threonine and isoleucine). A closed class.
imported from: chebi.owl
database_cross_reference: PMID:4386082
database_cross_reference: PMID:4394351
database_cross_reference: PMID:4721772
database_cross_reference: PMID:5016260
database_cross_reference: PMID:5074276
has_obo_namespace: chebi_ontology
has_related_synonym: aspartate family amino acids
has_related_synonym: aspartic acid family amino acid
has_related_synonym: aspartic acid family amino acids
has_related_synonym: oxaloacetate family amino acid
has_related_synonym: oxaloacetate family amino acids
has_related_synonym: oxaloacetate/aspartate family amino acid
has_related_synonym: oxaloacetate/aspartate family amino acids
id: CHEBI:22658
in subset: 3 STAR

aspartic acid
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: CHEBI_66873
subclass of: Restriction
  on property: has part
  some values from: CHEBI_41402
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: aspartate
subclass of: Restriction
  on property: is conjugate acid of
  some values from: aspartate(1-)
definition: An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
imported from: chebi.owl
charge: 0
formula: C4H7NO4
inchi: InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)
inchikey: CKLJMWTZIZZHCS-UHFFFAOYSA-N
mass: 133.10272
monoisotopicmass: 133.03751
smiles: NC(CC(O)=O)C(O)=O
database_cross_reference: Beilstein:774618
database_cross_reference: CAS:617-45-8
database_cross_reference: Gmelin:185140
database_cross_reference: KEGG:C16433
database_cross_reference: PMID:22264337
database_cross_reference: Reaxys:774618
database_cross_reference: Wikipedia:Aspartic_acid
has exact synonym: Aspartic acid
has exact synonym: aspartic acid
has_obo_namespace: chebi_ontology
has_related_synonym: (+-)-Aspartic acid
has_related_synonym: (R,S)-Aspartic acid
has_related_synonym: 2-aminobutanedioic acid
has_related_synonym: Asp
has_related_synonym: D
has_related_synonym: DL-Aminosuccinic acid
has_related_synonym: DL-Asparagic acid
id: CHEBI:22660
in subset: 3 STAR

bafilomycin A1
type: Class
subclass of: macrolide antibiotic
subclass of: CHEBI_46942
subclass of: CHEBI_59780
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004468
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR_000004480
subclass of: Restriction
  on property: has role
  some values from: ferroptosis inhibitor
subclass of: Restriction
  on property: has role
  some values from: fungicide
subclass of: Restriction
  on property: has role
  some values from: toxin
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49200
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
subclass of: Restriction
  on property: has role
  some values from: CHEBI_73214
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88227
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88230
subclass of: Restriction
  on property: has role
  some values from: ATPase motor cytoplasmic dynein inhibitor
definition: The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.
definition source: Reference: PMID: 9572882
imported from: chebi.owl
charge: 0
formula: C35H58O9
inchi: InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1
inchikey: XDHNQDDQEHDUTM-JQWOJBOSSA-N
mass: 622.82960
monoisotopicmass: 622.40808
database_cross_reference: Beilstein:3640011
database_cross_reference: Beilstein:4730699
database_cross_reference: Beilstein:4730700
database_cross_reference: CAS:88899-55-2
database_cross_reference: PMID:10519916
database_cross_reference: PMID:11533151
database_cross_reference: PMID:17917797
database_cross_reference: PMID:19067440
database_cross_reference: PMID:19289106
database_cross_reference: PMID:20820851
database_cross_reference: PMID:22344969
database_cross_reference: PMID:22943412
database_cross_reference: PMID:23038011
database_cross_reference: PMID:23480984
database_cross_reference: PMID:24890793
database_cross_reference: PMID:24977403
database_cross_reference: PMID:25512644
database_cross_reference: PMID:26156798
database_cross_reference: PMID:26242265
database_cross_reference: PMID:7817803
database_cross_reference: PMID:8446034
database_cross_reference: Reaxys:4730700
has exact synonym: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one
has_obo_namespace: chebi_ontology
id: CHEBI:22689
in subset: 3 STAR

base
type: Class
subclass of: CHEBI_51086
definition: A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
imported from: chebi.owl
database_cross_reference: KEGG:C00701
has exact synonym: Base
has exact synonym: base
has_obo_namespace: chebi_ontology
has_related_synonym: Base1
has_related_synonym: Base2
has_related_synonym: Basen
has_related_synonym: Nucleobase
has_related_synonym: bases
id: CHEBI:22695
in subset: 3 STAR

benzamides
type: Class
subclass of: arenecarboxamide
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22702
in subset: 3 STAR

benzenes
type: Class
subclass of: benzenoid aromatic compound
definition: Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22712
in subset: 3 STAR

benzimidazoles
type: Class
subclass of: organic heterobicyclic compound
subclass of: CHEBI_38101
definition: An organic heterocyclic compound containing a benzene ring fused to an imidazole ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22715
in subset: 3 STAR

benzoates
type: Class
subclass of: CHEBI_35757
definition: A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzoate anion
id: CHEBI:22718
in subset: 3 STAR

benzodiazepine
type: Class
subclass of: CHEBI_38101
subclass of: CHEBI_38166
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50268
definition: A group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzodiazepines
id: CHEBI:22720
in subset: 3 STAR

benzoic acids
type: Class
subclass of: benzenes
subclass of: aromatic carboxylic acid
definition: Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22723
in subset: 3 STAR

benzopyran
type: Class
subclass of: CHEBI_38104
subclass of: CHEBI_38166
imported from: chebi.owl
database_cross_reference: Wikipedia:Benzopyran
has_obo_namespace: chebi_ontology
has_related_synonym: benzopyrans
id: CHEBI:22727
in subset: 3 STAR

benzopyrrole
type: Class
subclass of: organic heterobicyclic compound
subclass of: CHEBI_38101
subclass of: CHEBI_38180
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzopyrroles
id: CHEBI:22728
in subset: 3 STAR

benzoquinones
type: Class
subclass of: CHEBI_36141
definition: Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their C-substituted derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22729
in subset: 3 STAR

benzyl alcohols
type: Class
subclass of: aromatic alcohol
definition: Compounds containing a phenylmethanol skeleton.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzylic alcohol
has_related_synonym: benzylic alcohols
id: CHEBI:22743
in subset: 3 STAR

benzyl group
type: Class
subclass of: benzylic group
subclass of: CHEBI_50325
subclass of: Restriction
  on property: is substituent group from
  some values from: toluene
imported from: chebi.owl
charge: 0
formula: C7H7
mass: 91.13048
monoisotopicmass: 91.05478
smiles: C1=C(C=CC=C1)C*
has exact synonym: benzyl
has_obo_namespace: chebi_ontology
has_related_synonym: Bn
has_related_synonym: C6H5-CH2-
has_related_synonym: phenylalanine side-chain
has_related_synonym: phenylmethyl
id: CHEBI:22744
in subset: 3 STAR

benzylisoquinoline alkaloid
type: Class
subclass of: isoquinoline alkaloid
definition: Any isoquinoline alkaloid based on a benzylisoquinoline skeleton.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzylisoquinoline alkaloids
id: CHEBI:22750
in subset: 3 STAR

amino-acid betaine
type: Class
subclass of: ammonium betaine
subclass of: CHEBI_83821
definition: Any amino acid-derived zwitterion - such as glycine betaine (N,N,N-trimethylammonioacetate) - in which the ammonium nitrogen carries methyl substituents and bears no hydrogen atoms.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: amino acid betaines
has_related_synonym: amino-acid betaines
has_related_synonym: betaines
id: CHEBI:22860
in subset: 3 STAR

biphenyls
type: Class
subclass of: benzenoid aromatic compound
subclass of: CHEBI_36820
subclass of: CHEBI_64459
definition: Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:22888
in subset: 3 STAR

branched-chain amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_63471
definition: Any amino acid in which the parent hydrocarbon chain has one or more alkyl substituents
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: branched chain amino acids
id: CHEBI:22918
in subset: 3 STAR

bromine atom
type: Class
subclass of: halogen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
imported from: chebi.owl
charge: 0
formula: Br
inchi: InChI=1S/Br
inchikey: WKBOTKDWSSQWDR-UHFFFAOYSA-N
mass: 79.90400
monoisotopicmass: 78.91834
smiles: [Br]
database_cross_reference: WebElements:Br
has exact synonym: bromine
has_obo_namespace: chebi_ontology
has_related_synonym: 35Br
has_related_synonym: Br
has_related_synonym: Brom
has_related_synonym: brome
has_related_synonym: bromine
has_related_synonym: bromo
has_related_synonym: bromum
id: CHEBI:22927
in subset: 3 STAR

bromine molecular entity
type: Class
subclass of: halogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: bromine atom
imported from: chebi.owl
has exact synonym: bromine molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: bromine compounds
has_related_synonym: bromine molecular entities
id: CHEBI:22928
in subset: 3 STAR

bufanolide
type: Class
subclass of: steroid lactone
subclass of: steroid fundamental parent
imported from: chebi.owl
charge: 0
formula: C24H38O2
inchi: InChI=1S/C24H38O2/c1-23-13-4-3-5-17(23)7-8-18-20-10-9-19(16-6-11-22(25)26-15-16)24(20,2)14-12-21(18)23/h16-21H,3-15H2,1-2H3/t16-,17?,18-,19+,20+,21-,23-,24+/m0/s1
inchikey: PXOHOSHERMSUCD-YQMMVUDVSA-N
mass: 358.55732
monoisotopicmass: 358.28718
has exact synonym: bufanolide
has_obo_namespace: chebi_ontology
id: CHEBI:22934
in subset: 3 STAR

carbamate ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: carbamic acid
definition: Any ester of carbamic acid or its N-substituted derivatives.
imported from: chebi.owl
database_cross_reference: Wikipedia:Carbamate
has_obo_namespace: chebi_ontology
has_related_synonym: carbamate esters
has_related_synonym: carbamates
id: CHEBI:23003
in subset: 3 STAR

carbamoyl group
type: Class
subclass of: univalent carboacyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: carbamic acid
definition: The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
imported from: chebi.owl
charge: 0
formula: CH2NO
mass: 44.03272
monoisotopicmass: 44.01364
smiles: *C(N)=O
database_cross_reference: PMID:24168430
has exact synonym: carbamoyl
has_obo_namespace: chebi_ontology
has_related_synonym: -C(O)NH2
has_related_synonym: -CONH2
has_related_synonym: aminocarbonyl
has_related_synonym: carbamyl
has_related_synonym: carbamyl group
has_related_synonym: carboxamide
id: CHEBI:23004
in subset: 3 STAR

carbohydrate-containing antibiotic
type: Class
subclass of: CHEBI_63299
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
definition: Any carbohydrate derivative that exhibits antibiotic activity.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23007
in subset: 3 STAR

carbonyl group
type: Class
subclass of: CHEBI_51422
imported from: chebi.owl
charge: 0
formula: CO
mass: 28.01010
monoisotopicmass: 27.99491
smiles: O=C(*)*
has exact synonym: carbonyl
has exact synonym: carbonyl group
has_obo_namespace: chebi_ontology
has_related_synonym: >C=O
id: CHEBI:23019
in subset: 3 STAR

chloride salt
type: Class
subclass of: chlorine molecular entity
subclass of: halide salt
subclass of: Restriction
  on property: has part
  some values from: chloride
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: chloride salts
has_related_synonym: chlorides
id: CHEBI:23114
in subset: 3 STAR

chlorine atom
type: Class
subclass of: halogen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
imported from: chebi.owl
charge: 0
formula: Cl
inchi: InChI=1S/Cl
inchikey: ZAMOUSCENKQFHK-UHFFFAOYSA-N
mass: 35.45270
monoisotopicmass: 34.96885
smiles: [Cl]
database_cross_reference: WebElements:Cl
has exact synonym: chlorine
has_obo_namespace: chebi_ontology
has_related_synonym: 17Cl
has_related_synonym: Chlor
has_related_synonym: Cl
has_related_synonym: chlore
has_related_synonym: chlorine
has_related_synonym: chlorum
has_related_synonym: cloro
id: CHEBI:23116
in subset: 3 STAR

chlorine molecular entity
type: Class
subclass of: halogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: chlorine atom
definition: A halogen molecular entity containing one or more atoms of chlorine.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23117
in subset: 3 STAR

chlorobenzenes
type: Class
subclass of: benzenes
subclass of: CHEBI_36683
definition: Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23132
in subset: 3 STAR

chlorobenzoate
type: Class
subclass of: benzoates
subclass of: Restriction
  on property: is conjugate base of
  some values from: chlorobenzoic acid
definition: Any member of the class of benzoates in which the benzene ring is substituted by at least one chloro group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: chlorobenzoates
id: CHEBI:23133
in subset: 3 STAR

chlorobenzoic acid
type: Class
subclass of: benzoic acids
subclass of: CHEBI_36685
subclass of: Restriction
  on property: is conjugate acid of
  some values from: chlorobenzoate
definition: Any member of the class of benzoic acids in which the benzene ring is substituted by at least one chloro group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: chlorobenzoic acids
id: CHEBI:23134
in subset: 3 STAR

cinnamamides
type: Class
subclass of: CHEBI_51751
subclass of: Restriction
  on property: has functional parent
  some values from: cinnamic acids
definition: An enamide which is cinnamamide or a derivative of cinnamamide obtained by replacement of one or more of its hydrogens.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23247
in subset: 3 STAR

cinnamic acids
type: Class
subclass of: CHEBI_78840
subclass of: CHEBI_79020
definition: Any alpha,beta-unsaturated monocarboxylic acid based on the cinnamic acid skeleton and its substituted derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23252
in subset: 3 STAR

cofactor
type: Class
subclass of: CHEBI_52206
definition: An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
imported from: chebi.owl
database_cross_reference: Wikipedia:Cofactor_(biochemistry)
has exact synonym: cofactor
has exact synonym: cofactors
has_obo_namespace: chebi_ontology
id: CHEBI:23357
in subset: 3 STAR

colchicine
type: Class
subclass of: acetamides
subclass of: alkaloid
subclass of: aromatic ether
subclass of: CHEBI_38032
subclass of: Restriction
  on property: has role
  some values from: CHEBI_61951
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
definition: An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.
imported from: chebi.owl
charge: 0
formula: C22H25NO6
inchi: InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
inchikey: IAKHMKGGTNLKSZ-UHFFFAOYSA-N
mass: 399.43704
monoisotopicmass: 399.16819
smiles: COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC
database_cross_reference: Beilstein:2228812
database_cross_reference: CAS:54192-66-4
database_cross_reference: DrugBank:DB01394
database_cross_reference: HMDB:HMDB0015466
database_cross_reference: LINCS:LSM-6449
database_cross_reference: PMID:10680067
database_cross_reference: PMID:24074178
database_cross_reference: PMID:7200520
database_cross_reference: PMID:9819133
database_cross_reference: Reaxys:2228812
has exact synonym: N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
has_obo_namespace: chebi_ontology
id: CHEBI:23359
in subset: 3 STAR

compatible osmolytes
type: Class
subclass of: osmolyte
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23366
in subset: 1 STAR

molecular entity
type: Class
subclass of: object
subclass of: material entity
subclass of: chemical entity
editor preferred label: molecular entity
definition: Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
editor note: We are assuming that every molecular entity has to be completely connected by chemical bonds. This excludes protein complexes, which are comprised of minimally two separate molecular entities. We will follow up with Chebi to ensure this is their understanding as well
imported from: chebi.owl
imported from: dron.owl
imported from: ido.owl
imported from: obi.owl
imported from: vo.owl
has exact synonym: molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: entidad molecular
has_related_synonym: entidades moleculares
has_related_synonym: entite moleculaire
has_related_synonym: molecular entities
has_related_synonym: molekulare Entitaet
id: CHEBI:23367
in subset: 3 STAR

cyanides
type: Class
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has parent hydride
  some values from: hydrogen cyanide
definition: Salts and C-organyl derivatives of hydrogen cyanide, HC#N.
imported from: chebi.owl
has exact synonym: cyanides
has_obo_namespace: chebi_ontology
id: CHEBI:23424
in subset: 3 STAR

cyclic amide
type: Class
subclass of: amide
imported from: chebi.owl
has_alternative_id: CHEBI:3990
has exact synonym: cyclic amide
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic amides
id: CHEBI:23443
in subset: 3 STAR

cyclic peptide
type: Class
subclass of: peptide
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Cyclopeptid
has_related_synonym: Zyklopeptid
has_related_synonym: cyclic peptides
has_related_synonym: peptide cyclique
has_related_synonym: peptido ciclico
id: CHEBI:23449
in subset: 3 STAR

cyclitol
type: Class
subclass of: polyol
definition: A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom.
imported from: dron.owl
has exact synonym: cyclitols
id: CHEBI:23451

cytidines
type: Class
subclass of: CHEBI_39446
subclass of: Restriction
  on property: has functional parent
  some values from: cytosine
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23524
in subset: 3 STAR

deoxyribonucleoside
type: Class
subclass of: nucleoside
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: deoxyribonucleosides
id: CHEBI:23636
in subset: 3 STAR

depsipeptide
type: Class
subclass of: peptide
definition: A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually alpha-amino and alpha-hydroxy acids), commonly but not necessarily regularly alternating.
imported from: chebi.owl
has exact synonym: depsipeptides
has_obo_namespace: chebi_ontology
has_related_synonym: Depsipeptid
id: CHEBI:23643
in subset: 3 STAR

diazole
type: Class
subclass of: CHEBI_68452
definition: An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: diazoles
id: CHEBI:23677
in subset: 3 STAR

dicarboxylic acid amide
type: Class
subclass of: CHEBI_37622
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acid amides
id: CHEBI:23690
in subset: 3 STAR

dichlorobenzene
type: Class
subclass of: chlorobenzenes
definition: Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
imported from: chebi.owl
charge: 0
formula: C6H4Cl2
mass: 147.002
monoisotopicmass: 145.96901
has exact synonym: dichlorobenzene
has_obo_namespace: chebi_ontology
has_related_synonym: Dichlorbenzol
has_related_synonym: dichlorobenzenes
id: CHEBI:23697
in subset: 3 STAR

quinolone
type: Class
subclass of: quinolines
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: quinolones
id: CHEBI:23765
in subset: 3 STAR

diol
type: Class
subclass of: polyol
definition: A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols.
imported from: chebi.owl
database_cross_reference: Wikipedia:Diol
has exact synonym: diols
has_obo_namespace: chebi_ontology
id: CHEBI:23824
in subset: 3 STAR

drug
type: Class
subclass of: CHEBI_52217
definition: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
alternative term: drug
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: drugs
has_related_synonym: medicine
id: CHEBI:23888
in subset: 3 STAR

monoatomic anion
type: Class
subclass of: anion
subclass of: monoatomic ion
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic anions
id: CHEBI:23905
in subset: 3 STAR

enzyme inhibitor
type: Class
subclass of: inhibitor
subclass of: CHEBI_52206
definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
imported from: chebi.owl
has exact synonym: enzyme inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme inhibitors
has_related_synonym: inhibidor enzimatico
has_related_synonym: inhibidores enzimaticos
has_related_synonym: inhibiteur enzymatique
has_related_synonym: inhibiteurs enzymatiques
id: CHEBI:23924
in subset: 3 STAR

ethanolamines
type: Class
subclass of: amino alcohol
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ethanolamine
id: CHEBI:23981
in subset: 3 STAR

ethanols
type: Class
subclass of: primary alcohol
definition: Any primary alcohol based on an ethanol skeleton.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:23982
in subset: 3 STAR

ethyl ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: ethanol
subclass of: Restriction
  on property: has functional parent
  some values from: carboxylic acid
definition: Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol.
imported from: chebi.owl
charge: 0
formula: C3H5O2R
mass: 73.07060
monoisotopicmass: 73.02895
smiles: CCOC([*])=O
has_alternative_id: CHEBI:85056
has_obo_namespace: chebi_ontology
has_related_synonym: carboxylic acid ethyl ester
has_related_synonym: carboxylic acid ethyl esters
has_related_synonym: ethyl carboxylate
has_related_synonym: ethyl carboxylates
has_related_synonym: ethyl esters
id: CHEBI:23990
in subset: 3 STAR

fatty alcohol
type: Class
subclass of: alcohol
subclass of: CHEBI_61697
definition: An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched.
imported from: chebi.owl
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: O[*]
database_cross_reference: LIPID_MAPS_class:LMFA05
database_cross_reference: MetaCyc:Fatty-Alcohols
database_cross_reference: Wikipedia:Fatty_alcohol
has exact synonym: fatty alcohol
has_obo_namespace: chebi_ontology
has_related_synonym: Fettalkohol
has_related_synonym: Fettalkohole
has_related_synonym: alcool gras
has_related_synonym: fatty alcohols
id: CHEBI:24026
in subset: 3 STAR

flavones
type: Class
subclass of: CHEBI_47916
definition: A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives.
imported from: chebi.owl
charge: 0
formula: C15O2R10
mass: 212.160
monoisotopicmass: 211.98983
database_cross_reference: MetaCyc:Flavones
database_cross_reference: Wikipedia:Flavone
has_obo_namespace: chebi_ontology
has_related_synonym: 2-aryl-1-benzopyran-4-one
has_related_synonym: 2-aryl-1-benzopyran-4-ones
has_related_synonym: 2-arylchromen-4-one
has_related_synonym: 2-arylchromen-4-ones
has_related_synonym: a flavone
id: CHEBI:24043
in subset: 3 STAR

fluorine atom
type: Class
subclass of: halogen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
imported from: chebi.owl
charge: 0
formula: F
inchi: InChI=1S/F
inchikey: YCKRFDGAMUMZLT-UHFFFAOYSA-N
mass: 18.99840
monoisotopicmass: 18.99840
smiles: [F]
database_cross_reference: CAS:7782-41-4
database_cross_reference: WebElements:F
has exact synonym: fluorine
has_obo_namespace: chebi_ontology
has_related_synonym: 9F
has_related_synonym: F
has_related_synonym: Fluor
has_related_synonym: fluor
has_related_synonym: fluorine
has_related_synonym: fluorum
id: CHEBI:24061
in subset: 3 STAR

fluorine molecular entity
type: Class
subclass of: halogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: fluorine atom
imported from: chebi.owl
imported from: dron.owl
has exact synonym: fluorine molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: fluorine compounds
has_related_synonym: fluorine molecular entities
id: CHEBI:24062
in subset: 3 STAR

fluoroalkane
type: Class
subclass of: haloalkane
subclass of: CHEBI_37143
definition: A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom.
imported from: chebi.owl
has exact synonym: fluoroalkane
has_obo_namespace: chebi_ontology
has_related_synonym: fluoroalkanes
id: CHEBI:24067
in subset: 3 STAR

formyltetrahydrofolic acid
type: Class
subclass of: tetrahydrofolic acid
imported from: chebi.owl
charge: 0
formula: C20H23N7O7
mass: 473.440
monoisotopicmass: 473.16590
has_obo_namespace: chebi_ontology
id: CHEBI:24099
in subset: 3 STAR

fungicide
type: Class
subclass of: pesticide
subclass of: CHEBI_35718
definition: A substance used to destroy fungal pests.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: fungicides
id: CHEBI:24127
in subset: 3 STAR

furans
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38104
definition: Compounds containing at least one furan ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: oxacyclopenta-2,4-dienes
id: CHEBI:24129
in subset: 3 STAR

geranylgeranyl group
type: Class
subclass of: polyprenyl group
imported from: chebi.owl
charge: 0
formula: C20H33
mass: 273.47602
monoisotopicmass: 273.25823
smiles: CC(=CCC/C(=C/CC/C(=C/CC/C(=C/C*)/C)/C)/C)C
has exact synonym: (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl
has_obo_namespace: chebi_ontology
has_related_synonym: (2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl group
id: CHEBI:24231
in subset: 3 STAR

glucocorticoid
type: Class
subclass of: CHEBI_36699
definition: Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: glucocorticoids
id: CHEBI:24261
in subset: 3 STAR

glucosiduronic acid
type: Class
subclass of: glycosiduronic acid
subclass of: CHEBI_63436
definition: Any substance produced by linking glucuronic acid to another substance via a glycosidic bond.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: glucosiduronic acids
has_related_synonym: glucuronide
id: CHEBI:24302
in subset: 3 STAR

glutamic acid derivative
type: Class
subclass of: CHEBI_83821
subclass of: Restriction
  on property: has functional parent
  some values from: glutamic acid
definition: An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24315
in subset: 3 STAR

glutamine family amino acid
type: Class
subclass of: L-alpha-amino acid
subclass of: CHEBI_83813
definition: An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class.
imported from: chebi.owl
database_cross_reference: PMID:20716061
has_obo_namespace: chebi_ontology
has_related_synonym: glutamine family amino acids
id: CHEBI:24318
in subset: 3 STAR

EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
type: Class
subclass of: CHEBI_76823
definition: An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).
imported from: chebi.owl
database_cross_reference: Wikipedia:Glutamine_synthetase
has_obo_namespace: chebi_ontology
has_related_synonym: EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
has_related_synonym: EC 6.3.1.2 inhibitor
has_related_synonym: EC 6.3.1.2 inhibitors
has_related_synonym: L-glutamate:ammonia ligase (ADP-forming) inhibitor
has_related_synonym: L-glutamate:ammonia ligase (ADP-forming) inhibitors
has_related_synonym: L-glutamine synthetase inhibitor
has_related_synonym: L-glutamine synthetase inhibitors
has_related_synonym: glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
has_related_synonym: glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
has_related_synonym: glutamate--ammonia ligase inhibitor
has_related_synonym: glutamate--ammonia ligase inhibitors
has_related_synonym: glutamine synthetase inhibitor
has_related_synonym: glutamine synthetase inhibitors
has_related_synonym: glutamylhydroxamic synthetase inhibitor
has_related_synonym: glutamylhydroxamic synthetase inhibitors
id: CHEBI:24319
in subset: 3 STAR

glycopeptide
type: Class
subclass of: peptide
subclass of: CHEBI_63299
definition: Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide.
imported from: chebi.owl
has_alternative_id: CHEBI:24395
has_alternative_id: CHEBI:5478
has exact synonym: glycopeptides
has_obo_namespace: chebi_ontology
id: CHEBI:24396
in subset: 3 STAR

glycoside
type: Class
subclass of: CHEBI_63161
definition: A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
definition: A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, which itself may be derived from a saccharide and chalcogen replacements thereof (RS-, RSe-). The bond between the glycosyl group and the OR group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: glycosides
has_obo_namespace: chebi_ontology
has_related_synonym: O-glycoside
has_related_synonym: O-glycosides
has_related_synonym: glycosides
id: CHEBI:24400
in subset: 3 STAR

chemical entity
type: Class
subclass of: material entity
definition: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
imported from: chebi.owl
imported from: dron.owl
imported from: vo.owl
has exact synonym: chemical entity
has_obo_namespace: chebi_ontology
id: CHEBI:24431
in subset: 3 STAR

biological role
type: Class
subclass of: CHEBI_50906
definition: A role played by the molecular entity or part thereof within a biological context.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: biological function
id: CHEBI:24432
in subset: 3 STAR

group
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: atom
definition: A defined linked collection of atoms or a single atom within a molecular entity.
imported from: chebi.owl
has exact synonym: group
has_obo_namespace: chebi_ontology
has_related_synonym: Gruppe
has_related_synonym: Rest
has_related_synonym: groupe
has_related_synonym: grupo
has_related_synonym: grupos
id: CHEBI:24433
in subset: 3 STAR

guanidines
type: Class
subclass of: organonitrogen compound
definition: Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24436
in subset: 3 STAR

haloalkane
type: Class
subclass of: halohydrocarbon
definition: A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: alkyl halide
has_related_synonym: alkyl halides
has_related_synonym: haloalkanes
id: CHEBI:24469
in subset: 3 STAR

halogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: halogen
imported from: chebi.owl
imported from: dron.owl
has exact synonym: halogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: halogen compounds
has_related_synonym: halogen molecular entities
id: CHEBI:24471
in subset: 3 STAR

halohydrocarbon
type: Class
subclass of: organohalogen compound
subclass of: Restriction
  on property: has parent hydride
  some values from: hydrocarbon
definition: A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: halogenated hydrocarbons
has_related_synonym: halohydrocarbons
id: CHEBI:24472
in subset: 3 STAR

halogen
type: Class
subclass of: nonmetal atom
subclass of: p-block element atom
imported from: chebi.owl
has exact synonym: halogen
has exact synonym: halogens
has_obo_namespace: chebi_ontology
has_related_synonym: Halogene
has_related_synonym: group 17 elements
has_related_synonym: group VII elements
has_related_synonym: halogene
has_related_synonym: halogenes
has_related_synonym: halogeno
has_related_synonym: halogenos
id: CHEBI:24473
in subset: 3 STAR

heterocyclic antibiotic
type: Class
subclass of: organic heterocyclic compound
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24531
in subset: 1 STAR

organic heterocyclic compound
type: Class
subclass of: heteroorganic entity
subclass of: organic cyclic compound
subclass of: CHEBI 5686
definition: A cyclic compound having as ring members atoms of carbon and at least of one other element.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic heterocycle
has_related_synonym: organic heterocyclic compounds
id: CHEBI:24532
in subset: 3 STAR

heterodetic cyclic peptide
type: Class
subclass of: cyclic peptide
definition: A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond.
imported from: chebi.owl
has exact synonym: heterodetic cyclic peptide
has_obo_namespace: chebi_ontology
has_related_synonym: heterodetic cyclic peptides
has_related_synonym: peptide cyclique heterodetique
has_related_synonym: peptido ciclico heterodetico
id: CHEBI:24533
in subset: 3 STAR

hexenoic acid
type: Class
subclass of: monounsaturated fatty acid
subclass of: CHEBI_59554
definition: A C6, medium-chain fatty acid carrying a double bond at any position along the main chain.
imported from: chebi.owl
charge: 0
formula: C6H10O2
mass: 114.143
monoisotopicmass: 114.06808
has exact synonym: hexenoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: hexenoic acids
id: CHEBI:24580
in subset: 3 STAR

homodetic cyclic peptide
type: Class
subclass of: cyclic peptide
definition: A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: homodetic cyclic peptide
has_obo_namespace: chebi_ontology
has_related_synonym: homodetic cyclic peptides
has_related_synonym: peptide cyclique homodetique
has_related_synonym: peptido ciclico homodetico
id: CHEBI:24613
in subset: 3 STAR

hormone
type: Class
subclass of: molecular messenger
subclass of: CHEBI_48705
definition: Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: endocrine
has_related_synonym: hormones
id: CHEBI:24621
in subset: 3 STAR

hydrazines
type: Class
subclass of: CHEBI_51143
definition: Hydrazine (diazane) and its substituted derivatives.
imported from: chebi.owl
has exact synonym: hydrazines
has_obo_namespace: chebi_ontology
id: CHEBI:24631
in subset: 3 STAR

hydrocarbon
type: Class
subclass of: organic fundamental parent
definition: A compound consisting of carbon and hydrogen only.
imported from: chebi.owl
has exact synonym: hydrocarbon
has exact synonym: hydrocarbons
has_obo_namespace: chebi_ontology
has_related_synonym: Kohlenwasserstoff
has_related_synonym: Kohlenwasserstoffe
has_related_synonym: hidrocarburo
has_related_synonym: hidrocarburos
has_related_synonym: hydrocarbure
id: CHEBI:24632
in subset: 3 STAR

hydroxamic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydroxamic acid
definition: An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxamate
has_related_synonym: hydroxamates
has_related_synonym: hydroxamic acid anions
has_related_synonym: hydroxamic anion
has_related_synonym: hydroxamic anions
id: CHEBI:24648
in subset: 3 STAR

hydroxamic acid
type: Class
subclass of: CHEBI_37622
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydroxamic acid anion
definition: A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l =/= 0) by replacing -OH with -NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides.
imported from: chebi.owl
has exact synonym: hydroxamic acids
has_obo_namespace: chebi_ontology
has_related_synonym: N-hydroxy amide
has_related_synonym: N-hydroxy amides
has_related_synonym: N-hydroxy-amide
has_related_synonym: N-hydroxy-amides
has_related_synonym: N-hydroxyamide
has_related_synonym: N-hydroxyamides
has_related_synonym: hydroxamic acids
id: CHEBI:24650
in subset: 3 STAR

hydroxides
type: Class
subclass of: oxygen molecular entity
subclass of: hydrogen molecular entity
subclass of: CHEBI_37577
subclass of: Restriction
  on property: has part
  some values from: CHEBI_43176
definition: Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24651
in subset: 3 STAR

hydroxy carboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: organic hydroxy compound
definition: Any carboxylic acid with at least one hydroxy group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxy carboxylic acids
has_related_synonym: hydroxycarboxylic acid
has_related_synonym: hydroxycarboxylic acids
id: CHEBI:24669
in subset: 3 STAR

hydroxybenzoate
type: Class
subclass of: benzoates
subclass of: CHEBI_36059
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydroxybenzoic acid
definition: Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxybenzoates
id: CHEBI:24675
in subset: 3 STAR

hydroxybenzoic acid
type: Class
subclass of: benzoic acids
subclass of: phenols
subclass of: Restriction
  on property: has functional parent
  some values from: benzoic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydroxybenzoate
definition: Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring.
imported from: chebi.owl
charge: 0
formula: C7H6O3
mass: 138.121
monoisotopicmass: 138.03169
has_alternative_id: CHEBI:50778
has exact synonym: hydroxybenzoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxybenzoic acids
id: CHEBI:24676
in subset: 3 STAR

hydroxyflavanone
type: Class
subclass of: flavanones
subclass of: organic hydroxy compound
definition: A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents.
imported from: chebi.owl
has exact synonym: hydroxyflavanone
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxyflavanones
id: CHEBI:24697
in subset: 3 STAR

hydroxyflavone
type: Class
subclass of: flavones
subclass of: organic hydroxy compound
definition: Any flavone in which one or more ring hydrogens are replaced by hydroxy groups.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: hydroxyflavones
id: CHEBI:24698
in subset: 3 STAR

hydroxymethyl group
type: Class
subclass of: CHEBI_50325
subclass of: Restriction
  on property: is substituent group from
  some values from: methanol
imported from: chebi.owl
charge: 0
formula: CH3O
mass: 31.03392
monoisotopicmass: 31.01839
smiles: C(*)O
has exact synonym: hydroxymethyl
has_obo_namespace: chebi_ontology
has_related_synonym: -CH2-OH
has_related_synonym: serine side-chain
id: CHEBI:24712
in subset: 3 STAR

imidazoles
type: Class
subclass of: diazole
definition: A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24780
in subset: 3 STAR

imide
type: Class
subclass of: secondary amide
imported from: chebi.owl
has exact synonym: imide
has_obo_namespace: chebi_ontology
has_related_synonym: imides
id: CHEBI:24782
in subset: 3 STAR

indanones
type: Class
subclass of: CHEBI 3992
subclass of: CHEBI_46940
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24789
in subset: 1 STAR

indole-3-acetic acids
type: Class
subclass of: indol-3-yl carboxylic acid
subclass of: Restriction
  on property: has functional parent
  some values from: acetic acid
definition: An indol-3-yl carboxylic acid in which the carboxylic acid specified is acetic acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24803
in subset: 3 STAR

indol-3-yl carboxylic acid
type: Class
subclass of: CHEBI_46867
definition: Any indolyl carboxylic acid carrying an indol-3-yl or substituted indol-3-yl group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: indol-3-yl carboxylic acids
id: CHEBI:24810
in subset: 3 STAR

indoles
type: Class
subclass of: benzopyrrole
definition: Any compound containing an indole skeleton.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24828
in subset: 3 STAR

oxoacid
type: Class
subclass of: hydroxides
subclass of: Restriction
  on property: has role
  some values from: CHEBI_39141
definition: A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
imported from: chebi.owl
imported from: dron.owl
has exact synonym: oxoacid
has exact synonym: oxoacids
has_obo_namespace: chebi_ontology
has_related_synonym: oxacids
has_related_synonym: oxiacids
has_related_synonym: oxo acid
has_related_synonym: oxy-acids
has_related_synonym: oxyacids
id: CHEBI:24833
in subset: 3 STAR

inorganic anion
type: Class
subclass of: anion
subclass of: CHEBI_36914
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic anions
id: CHEBI:24834
in subset: 3 STAR

inorganic molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity that contains no carbon.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: anorganische Verbindungen
has_related_synonym: inorganic compounds
has_related_synonym: inorganic entity
has_related_synonym: inorganic molecular entities
has_related_synonym: inorganics
id: CHEBI:24835
in subset: 3 STAR

inorganic oxide
type: Class
subclass of: inorganic molecular entity
subclass of: oxide
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic oxides
id: CHEBI:24836
in subset: 3 STAR

inorganic salt
type: Class
subclass of: inorganic molecular entity
subclass of: salt
imported from: dron.owl
has_related_synonym: anorganisches Salz
has_related_synonym: inorganic salts
id: CHEBI:24839

insecticide
type: Class
subclass of: pesticide
definition: Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
imported from: chebi.owl
database_cross_reference: Wikipedia:Insecticide
has_obo_namespace: chebi_ontology
has_related_synonym: insecticides
id: CHEBI:24852
in subset: 3 STAR

iodine atom
type: Class
subclass of: halogen
subclass of: Restriction
  on property: has role
  some values from: micronutrient
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
definition: Chemical element with atomic number 53.
imported from: chebi.owl
charge: 0
formula: I
inchi: InChI=1S/I
inchikey: ZCYVEMRRCGMTRW-UHFFFAOYSA-N
mass: 126.90447
monoisotopicmass: 126.90447
smiles: [I]
database_cross_reference: WebElements:I
has exact synonym: iodine
has_obo_namespace: chebi_ontology
has_related_synonym: 53I
has_related_synonym: I
has_related_synonym: Iod
has_related_synonym: J
has_related_synonym: Jod
has_related_synonym: iode
has_related_synonym: iodine
has_related_synonym: iodium
has_related_synonym: yodo
id: CHEBI:24859
in subset: 3 STAR

iodine molecular entity
type: Class
subclass of: halogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: iodine atom
imported from: chebi.owl
has exact synonym: iodine molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: iodine compounds
has_related_synonym: iodine molecular entities
id: CHEBI:24860
in subset: 3 STAR

salt
type: Class
subclass of: CHEBI_37577
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: CHEBI_36916
definition: A salt is an assembly of cations and anions.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: salt
has_obo_namespace: chebi_ontology
has_related_synonym: Salz
has_related_synonym: Salze
has_related_synonym: ionic compound
has_related_synonym: ionic compounds
has_related_synonym: sal
has_related_synonym: sales
has_related_synonym: salts
has_related_synonym: sel
has_related_synonym: sels
id: CHEBI:24866
in subset: 3 STAR

monoatomic ion
type: Class
subclass of: ion
subclass of: monoatomic entity
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic ions
id: CHEBI:24867
in subset: 3 STAR

organic salt
type: Class
subclass of: salt
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic salts
has_related_synonym: organisches Salz
id: CHEBI:24868
in subset: 3 STAR

ionophore
type: Class
subclass of: CHEBI_38632
definition: A compound which can carry specific ions through membranes of cells or organelles.
imported from: chebi.owl
database_cross_reference: Wikipedia:Ionophore
has exact synonym: ionophore
has_obo_namespace: chebi_ontology
has_related_synonym: ionophores
id: CHEBI:24869
in subset: 3 STAR

ion
type: Class
subclass of: molecular entity
definition: A molecular entity having a net electric charge.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: Ion
has exact synonym: ion
has_obo_namespace: chebi_ontology
has_related_synonym: Ionen
has_related_synonym: iones
has_related_synonym: ions
id: CHEBI:24870
in subset: 3 STAR

isoindoles
type: Class
subclass of: benzopyrrole
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24897
in subset: 3 STAR

isoleucine
type: Class
subclass of: CHEBI_38264
subclass of: Restriction
  on property: has part
  some values from: CHEBI_45557
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: isoleucinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: isoleucinium
definition: A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration.
imported from: chebi.owl
charge: 0
formula: C6H13NO2
mass: 131.175
monoisotopicmass: 131.09463
database_cross_reference: Beilstein:1721790
database_cross_reference: CAS:443-79-8
database_cross_reference: PMID:17190852
database_cross_reference: Reaxys:1721790
has exact synonym: isoleucine
has_obo_namespace: chebi_ontology
has_related_synonym: Hile
has_related_synonym: rel-(2R,3R)-2-amino-3-methylpentanoic acid
id: CHEBI:24898
in subset: 3 STAR

isoprenoid
type: Class
subclass of: lipid
subclass of: CHEBI_50860
definition: Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.
imported from: chebi.owl
database_cross_reference: LIPID_MAPS_class:LMPR01
database_cross_reference: PMID:12769708
database_cross_reference: PMID:19219049
has exact synonym: isoprenoid
has exact synonym: isoprenoids
has_obo_namespace: chebi_ontology
has_related_synonym: isoprenoids
id: CHEBI:24913
in subset: 3 STAR

isoquinoline alkaloid
type: Class
subclass of: alkaloid
definition: Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: isoquinoline alkaloids
id: CHEBI:24921
in subset: 3 STAR

isoquinolines
type: Class
subclass of: CHEBI_38101
subclass of: CHEBI_38166
definition: A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:24922
in subset: 3 STAR

ketoxime
type: Class
subclass of: oxime
definition: Oximes of ketones R2C=NOH (where R =/= H).
imported from: chebi.owl
charge: 0
formula: CHNOR2
mass: 43.02470
monoisotopicmass: 43.00581
smiles: O\N=C(\[*])[*]
has exact synonym: ketoxime
has exact synonym: ketoximes
has_obo_namespace: chebi_ontology
has_related_synonym: ketoximes
id: CHEBI:24983
in subset: 3 STAR

lactam
type: Class
subclass of: cyclic amide
subclass of: CHEBI_37622
subclass of: CHEBI_38101
definition: Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
imported from: chebi.owl
has exact synonym: lactam
has exact synonym: lactams
has_obo_namespace: chebi_ontology
has_related_synonym: Laktam
has_related_synonym: Laktame
has_related_synonym: lactams
id: CHEBI:24995
in subset: 3 STAR

Aescin
type: Class
subclass of: CHEBI_61778
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
definition source: PMID: 15226499
imported from: chebi.owl
charge: 0
formula: C55H86O24
inchi: InChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10-/t26-,27+,28+,29+,30+,31+,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42-,43-,44-,47-,48-,49+,51-,52+,53+,54+,55-/m0/s1
inchikey: AXNVHPCVMSNXNP-OXPBSUTMSA-N
mass: 1131.259
monoisotopicmass: 1130.55090
database_cross_reference: CAS:6805-41-0
database_cross_reference: KEGG:C08921
database_cross_reference: KEGG:D07912
database_cross_reference: KNApSAcK:C00003497
has exact synonym: Aescin
has_obo_namespace: chebi_ontology
has_related_synonym: Escin
id: CHEBI:2500
in subset: 2 STAR

lactone
type: Class
subclass of: carboxylic ester
subclass of: ester
subclass of: CHEBI_38104
definition: Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: lactone
has exact synonym: lactones
has_obo_namespace: chebi_ontology
has_related_synonym: Lacton
has_related_synonym: Lakton
has_related_synonym: Laktone
has_related_synonym: lactona
has_related_synonym: lactonas
id: CHEBI:25000
in subset: 3 STAR

leucine
type: Class
subclass of: branched-chain amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: isobutyl group
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: leucinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: leucinium
definition: A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.
imported from: chebi.owl
charge: 0
formula: C6H13NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)
inchikey: ROHFNLRQFUQHCH-UHFFFAOYSA-N
mass: 131.17296
monoisotopicmass: 131.09463
smiles: CC(C)CC(N)C(O)=O
database_cross_reference: Beilstein:636005
database_cross_reference: CAS:328-39-2
database_cross_reference: Gmelin:50203
database_cross_reference: KEGG:C16439
database_cross_reference: LIPID_MAPS_instance:LMFA01100048
database_cross_reference: PMID:17439666
database_cross_reference: Reaxys:636005
database_cross_reference: Wikipedia:Leucine
has exact synonym: leucine
has_obo_namespace: chebi_ontology
has_related_synonym: (+-)-Leucine
has_related_synonym: (RS)-Leucine
has_related_synonym: 2-amino-4-methylpentanoic acid
has_related_synonym: DL-Leucine
has_related_synonym: Hleu
has_related_synonym: L
has_related_synonym: Leu
has_related_synonym: Leucin
has_related_synonym: Leuzin
id: CHEBI:25017
in subset: 3 STAR

L-leucine derivative
type: Class
subclass of: CHEBI_47003
subclass of: CHEBI_83811
subclass of: Restriction
  on property: has functional parent
  some values from: L-leucine
definition: A proteinogenic amino acid derivative resulting from reaction of L-leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-leucine by a heteroatom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:25018
in subset: 3 STAR

lysine
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: CHEBI_35987
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50339
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: has functional parent
  some values from: hexanoic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: lysinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: lysinium(1+)
definition: A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.
imported from: chebi.owl
charge: 0
formula: C6H14N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)
inchikey: KDXKERNSBIXSRK-UHFFFAOYSA-N
mass: 146.18764
monoisotopicmass: 146.10553
smiles: NCCCCC(N)C(O)=O
database_cross_reference: Beilstein:1616991
database_cross_reference: CAS:70-54-2
database_cross_reference: Gmelin:279284
database_cross_reference: KEGG:C16440
database_cross_reference: PMID:17439666
database_cross_reference: PMID:22264337
database_cross_reference: Reaxys:1616991
database_cross_reference: Wikipedia:Lysine
has exact synonym: 2,6-diaminohexanoic acid
has exact synonym: lysine
has_obo_namespace: chebi_ontology
has_related_synonym: K
has_related_synonym: LYS
has_related_synonym: Lysin
has_related_synonym: alpha,epsilon-diaminocaproic acid
id: CHEBI:25094
in subset: 3 STAR

macrolide antibiotic
type: Class
subclass of: macrolide
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
definition: A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Makrolidantibiotika
has_related_synonym: macrolide antibiotics
id: CHEBI:25105
in subset: 3 STAR

macrolide
type: Class
subclass of: polyketide
subclass of: CHEBI_63944
definition: A macrocyclic lactone with a ring of twelve or more members derived from a polyketide.
imported from: chebi.owl
imported from: dron.owl
database_cross_reference: Wikipedia:Macrolide
has exact synonym: macrolide
has exact synonym: macrolides
has_obo_namespace: chebi_ontology
has_related_synonym: Makrolid
has_related_synonym: macrolides
id: CHEBI:25106
in subset: 3 STAR

metabolite
type: Class
subclass of: CHEBI_52206
definition: Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
imported from: chebi.owl
has_alternative_id: CHEBI:26619
has_alternative_id: CHEBI:35220
has exact synonym: metabolite
has_obo_namespace: chebi_ontology
has_related_synonym: metabolites
has_related_synonym: primary metabolites
has_related_synonym: secondary metabolites
id: CHEBI:25212
in subset: 3 STAR

methanesulfonate
type: Class
subclass of: CHEBI_62081
subclass of: Restriction
  on property: is conjugate base of
  some values from: methanesulfonic acid
definition: A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid.
imported from: chebi.owl
charge: -1
formula: CH3O3S
inchi: InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1
inchikey: AFVFQIVMOAPDHO-UHFFFAOYSA-M
mass: 95.09872
monoisotopicmass: 94.98084
smiles: CS([O-])(=O)=O
database_cross_reference: MetaCyc:CPD-3746
database_cross_reference: UM-BBD_compID:c0347
has exact synonym: methanesulfonate
has_obo_namespace: chebi_ontology
has_related_synonym: methylsulfonate
id: CHEBI:25224
in subset: 3 STAR

monomethoxybenzene
type: Class
subclass of: CHEBI_51683
definition: Compounds containing a benzene skeleton substituted with one methoxy group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monomethoxybenzenes
id: CHEBI:25235
in subset: 3 STAR

methyl ester
type: Class
subclass of: carboxylic ester
subclass of: Restriction
  on property: has functional parent
  some values from: methanol
definition: Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol.
imported from: chebi.owl
charge: 0
formula: C2H3O2R
mass: 59.044
monoisotopicmass: 59.01330
smiles: COC([*])=O
has_obo_namespace: chebi_ontology
has_related_synonym: carboxylic acid methyl ester
has_related_synonym: carboxylic acid methyl esters
id: CHEBI:25248
in subset: 3 STAR

mitochondrial respiratory-chain inhibitor
type: Class
subclass of: CHEBI_38497
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: mitochondrial electron transport chain inhibitors
has_related_synonym: mitochondrial electron-transport chain inhibitor
has_related_synonym: mitochondrial respiratory chain inhibitors
id: CHEBI:25355
in subset: 3 STAR

modified amino acid
type: Class
subclass of: amino acid
imported from: dron.owl
id: CHEBI:25359

molecule
type: Class
subclass of: CHEBI_36357
definition: Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
imported from: chebi.owl
has exact synonym: molecule
has_obo_namespace: chebi_ontology
has_related_synonym: Molekuel
has_related_synonym: molecula
has_related_synonym: molecules
has_related_synonym: neutral molecular compounds
id: CHEBI:25367
in subset: 3 STAR

monocarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_35757
definition: An oxoacid containing a single carboxy group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monocarboxylic acids
id: CHEBI:25384
in subset: 3 STAR

monohydroxybenzoate
type: Class
subclass of: hydroxybenzoate
definition: A hydroxybenzoate carrying a single hydroxy substituent at unspecified position.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monohydroxybenzoates
id: CHEBI:25388
in subset: 3 STAR

monohydroxybenzoic acid
type: Class
subclass of: hydroxybenzoic acid
definition: Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monohydroxybenzoic acids
id: CHEBI:25389
in subset: 3 STAR

monounsaturated fatty acid
type: Class
subclass of: unsaturated fatty acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_82680
definition: Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment.
imported from: chebi.owl
database_cross_reference: PMID:10584045
database_cross_reference: PMID:12936956
has_obo_namespace: chebi_ontology
has_related_synonym: MUFA
has_related_synonym: MUFAs
has_related_synonym: monounsaturated fatty acids
id: CHEBI:25413
in subset: 3 STAR

morphinane alkaloid
type: Class
subclass of: isoquinoline alkaloid
definition: An isoquinoline alkaloid based on a morphinan skeleton and its substituted derivatives.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: morphinane alkaloids
id: CHEBI:25418
in subset: 3 STAR

mutagen
type: Class
subclass of: CHEBI_50902
definition: An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
imported from: chebi.owl
database_cross_reference: Wikipedia:Mutagen
has_obo_namespace: chebi_ontology
has_related_synonym: mutagene
has_related_synonym: mutagenes
has_related_synonym: mutagenic agent
has_related_synonym: mutageno
has_related_synonym: mutagenos
has_related_synonym: mutagens
id: CHEBI:25435
in subset: 3 STAR

mycotoxin
type: Class
subclass of: toxin
subclass of: CHEBI_76946
definition: Poisonous substance produced by fungi.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: fungal toxins
has_related_synonym: mycotoxins
id: CHEBI:25442
in subset: 3 STAR

naphthalenes
type: Class
subclass of: benzenoid aromatic compound
subclass of: CHEBI_36785
definition: Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:25477
in subset: 3 STAR

naphthoate
type: Class
subclass of: CHEBI_35757
subclass of: Restriction
  on property: is conjugate base of
  some values from: naphthoic acid
imported from: chebi.owl
charge: 0
formula: C11H7O2
mass: 171.172
monoisotopicmass: 171.04460
has exact synonym: naphthalenecarboxylate
has_obo_namespace: chebi_ontology
id: CHEBI:25482
in subset: 3 STAR

naphthoic acid
type: Class
subclass of: naphthalenes
subclass of: aromatic carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: naphthoate
definition: An aromatic carboxylic acid that consists of a naphthalene skeleton substituted by one or more carboxy groups.
imported from: chebi.owl
charge: 0
formula: C11H8O2
mass: 172.180
monoisotopicmass: 172.05243
has exact synonym: naphthalenecarboxylic acid
has_obo_namespace: chebi_ontology
id: CHEBI:25483
in subset: 3 STAR

nematicide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the phylum Nematoda (roundworms).
imported from: chebi.owl
database_cross_reference: Wikipedia:Nematicide
has_obo_namespace: chebi_ontology
has_related_synonym: nematicides
has_related_synonym: nematocide
has_related_synonym: nematocides
id: CHEBI:25491
in subset: 3 STAR

neurotransmitter
type: Class
subclass of: molecular messenger
definition: An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
imported from: chebi.owl
database_cross_reference: Wikipedia:Neurotransmitter
has_obo_namespace: chebi_ontology
has_related_synonym: neurotransmitters
id: CHEBI:25512
in subset: 3 STAR

nigerans
type: Class
subclass of: CHEBI_37163
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:25541
in subset: 3 STAR

nitrogen atom
type: Class
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
imported from: chebi.owl
charge: 0
formula: N
mass: 14.007
monoisotopicmass: 14.00307
database_cross_reference: WebElements:N
has exact synonym: nitrogen
has_obo_namespace: chebi_ontology
has_related_synonym: 7N
has_related_synonym: N
has_related_synonym: Stickstoff
has_related_synonym: azote
has_related_synonym: nitrogen
has_related_synonym: nitrogeno
id: CHEBI:25555
in subset: 3 STAR

organonitrogen heterocyclic antibiotic
type: Class
subclass of: heterocyclic antibiotic
subclass of: CHEBI_38101
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organonitrogen heterocyclic antibiotics
id: CHEBI:25558
in subset: 3 STAR

nonmetal atom
type: Class
subclass of: atom
imported from: chebi.owl
has exact synonym: nonmetal
has_obo_namespace: chebi_ontology
has_related_synonym: Nichtmetall
has_related_synonym: Nichtmetalle
has_related_synonym: no metal
has_related_synonym: no metales
has_related_synonym: non-metal
has_related_synonym: non-metaux
has_related_synonym: nonmetal
has_related_synonym: nonmetals
id: CHEBI:25585
in subset: 3 STAR

octadecenoic acid
type: Class
subclass of: long-chain fatty acid
subclass of: monounsaturated fatty acid
subclass of: CHEBI_53339
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_78049
definition: Any member of the group of C18 monounsaturated fatty acids with the double bond located at any position in the chain.
imported from: chebi.owl
charge: 0
formula: C18H34O2
mass: 282.462
monoisotopicmass: 282.25588
database_cross_reference: PMID:18832207
database_cross_reference: PMID:19106329
database_cross_reference: PMID:7276754
has exact synonym: octadecenoic acid
has_obo_namespace: chebi_ontology
id: CHEBI:25634
in subset: 3 STAR

oligomycin
type: Class
subclass of: macrolide antibiotic
subclass of: macrolide
subclass of: CHEBI_72600
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: ATP synthase inhibitor
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases.
definition source: PMID: 30918074
imported from: chebi.owl
charge: 0
formula: C43H64O10R5
mass: 740.964
monoisotopicmass: 740.44995
database_cross_reference: Wikipedia:Oligomycin
has_obo_namespace: chebi_ontology
has_related_synonym: oligomycins
id: CHEBI:25675
in subset: 3 STAR

oligopeptide
type: Class
subclass of: peptide
definition: A peptide containing a relatively small number of amino acids.
imported from: chebi.owl
has_alternative_id: CHEBI:7755
database_cross_reference: Wikipedia:Oligopeptide
has exact synonym: oligopeptides
has_obo_namespace: chebi_ontology
has_related_synonym: Oligopeptid
has_related_synonym: oligopeptido
id: CHEBI:25676
in subset: 3 STAR

organic heteromonocyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heteromonocyclic compound
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic heteromonocyclic compounds
id: CHEBI:25693
in subset: 3 STAR

organic anion
type: Class
subclass of: anion
subclass of: organic ion
definition: Any organic ion with a net negative charge.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic anions
id: CHEBI:25696
in subset: 3 STAR

organic cation
type: Class
subclass of: organic ion
subclass of: CHEBI_36916
definition: Any organic ion with a net positive charge.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic cations
id: CHEBI:25697
in subset: 3 STAR

ether
type: Class
subclass of: CHEBI_36963
definition: An organooxygen compound with formula ROR, where R is not hydrogen.
imported from: chebi.owl
charge: 0
formula: OR2
mass: 15.99940
monoisotopicmass: 15.99491
smiles: [*]O[*]
has exact synonym: ether
has exact synonym: ethers
has_obo_namespace: chebi_ontology
has_related_synonym: ethers
id: CHEBI:25698
in subset: 3 STAR

organic ion
type: Class
subclass of: ion
subclass of: CHEBI_50860
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic ions
id: CHEBI:25699
in subset: 3 STAR

aliphatic alcohol
type: Class
subclass of: alcohol
definition: An alcohol derived from an aliphatic compound.
imported from: chebi.owl
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: O*
database_cross_reference: KEGG:C02525
has exact synonym: Aliphatic alcohol
has_obo_namespace: chebi_ontology
has_related_synonym: aliphatic alcohols
has_related_synonym: an aliphatic alcohol
id: CHEBI:2571
in subset: 3 STAR

osmolyte
type: Class
subclass of: biological role
definition: A solute used by a cell under water stress to maintain cell volume.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: osmolytes
id: CHEBI:25728
in subset: 3 STAR

oxide
type: Class
subclass of: oxygen molecular entity
subclass of: CHEBI_37577
definition: An oxide is a chemical compound of oxygen with other chemical elements.
imported from: chebi.owl
has exact synonym: oxide
has_obo_namespace: chebi_ontology
has_related_synonym: oxides
id: CHEBI:25741
in subset: 3 STAR

oxime
type: Class
subclass of: CHEBI_50860
subclass of: CHEBI_51143
subclass of: Restriction
  on property: is conjugate acid of
  some values from: oxime anion
definition: Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.
imported from: chebi.owl
charge: 0
formula: CHNOR2
mass: 43.02470
monoisotopicmass: 43.00581
smiles: O\N=C(\[*])[*]
has exact synonym: oxime
has exact synonym: oximes
has_obo_namespace: chebi_ontology
has_related_synonym: oximes
id: CHEBI:25750
in subset: 3 STAR

unsaturated fatty acid anion
type: Class
subclass of: fatty acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: unsaturated fatty acid
definition: Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:2580
in subset: 3 STAR

oxygen atom
type: Class
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
imported from: chebi.owl
charge: 0
formula: O
inchi: InChI=1S/O
inchikey: QVGXLLKOCUKJST-UHFFFAOYSA-N
mass: 15.99940
monoisotopicmass: 15.99491
smiles: [O]
database_cross_reference: KEGG:C00007
database_cross_reference: WebElements:O
has exact synonym: oxygen
has_obo_namespace: chebi_ontology
has_related_synonym: 8O
has_related_synonym: O
has_related_synonym: Sauerstoff
has_related_synonym: oxigeno
has_related_synonym: oxygen
has_related_synonym: oxygene
id: CHEBI:25805
in subset: 3 STAR

oxygen molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: oxygen atom
imported from: chebi.owl
imported from: dron.owl
has exact synonym: oxygen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: oxygen molecular entities
id: CHEBI:25806
in subset: 3 STAR

organooxygen heterocyclic antibiotic
type: Class
subclass of: heterocyclic antibiotic
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:25807
in subset: 1 STAR

oxopurine
type: Class
subclass of: purines
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: oxopurines
id: CHEBI:25810
in subset: 3 STAR

p-quinones
type: Class
subclass of: CHEBI_36141
definition: A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: p-quinone
has_related_synonym: para-quinones
id: CHEBI:25830
in subset: 3 STAR

pentacyclic triterpenoid
type: Class
subclass of: CHEBI_36615
subclass of: CHEBI_51958
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: pentacyclic triterpenoids
id: CHEBI:25872
in subset: 3 STAR

pentahydroxyflavone
type: Class
subclass of: hydroxyflavone
definition: A hydroxyflavone substituted by five hydroxy groups.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: pentahydroxyflavones
id: CHEBI:25883
in subset: 3 STAR

peptide antibiotic
type: Class
subclass of: peptide
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
definition: A chemically diverse class of peptides that exhibit antimicrobial properties.
imported from: chebi.owl
database_cross_reference: MetaCyc:Peptide-Antibiotics
database_cross_reference: PMID:33398258
has_obo_namespace: chebi_ontology
has_related_synonym: peptide antibiotics
id: CHEBI:25903
in subset: 3 STAR

peptide hormone
type: Class
subclass of: peptide
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: peptide hormones
has_related_synonym: polypeptide hormone
id: CHEBI:25905
in subset: 3 STAR

pesticide
type: Class
subclass of: application
definition: Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
imported from: chebi.owl
database_cross_reference: Wikipedia:Pesticide
has exact synonym: pesticide
has_obo_namespace: chebi_ontology
has_related_synonym: Pestizid
has_related_synonym: Pestizide
has_related_synonym: pesticides
id: CHEBI:25944
in subset: 3 STAR

phenylalanine derivative
type: Class
subclass of: CHEBI_83821
subclass of: Restriction
  on property: has functional parent
  some values from: phenylalanine
definition: An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine by a heteroatom. The definition normally excludes peptides containing phenylalanine residues.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:25985
in subset: 3 STAR

phenylpropanoid
type: Class
subclass of: organic aromatic compound
definition: Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin.
imported from: chebi.owl
database_cross_reference: Wikipedia:Phenylpropanoid
has_obo_namespace: chebi_ontology
has_related_synonym: phenylpropanoids
id: CHEBI:26004
in subset: 3 STAR

phosphoric acid
type: Class
subclass of: CHEBI_59698
subclass of: Restriction
  on property: has role
  some values from: fertilizer
subclass of: Restriction
  on property: has role
  some values from: CHEBI_46787
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_35780
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_39745
definition: A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom.
imported from: chebi.owl
charge: 0
formula: H3O4P
inchi: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
inchikey: NBIIXXVUZAFLBC-UHFFFAOYSA-N
mass: 97.99520
monoisotopicmass: 97.97690
smiles: [H]OP(=O)(O[H])O[H]
database_cross_reference: Beilstein:1921286
database_cross_reference: CAS:7664-38-2
database_cross_reference: Drug_Central:4478
database_cross_reference: Gmelin:2000
database_cross_reference: HMDB:HMDB0002142
database_cross_reference: KEGG:C00009
database_cross_reference: KEGG:D05467
database_cross_reference: KNApSAcK:C00007408
database_cross_reference: PMID:11455380
database_cross_reference: PMID:15630224
database_cross_reference: PMID:17439666
database_cross_reference: PMID:17518491
database_cross_reference: PMID:22282755
database_cross_reference: PMID:22333268
database_cross_reference: PMID:22381614
database_cross_reference: PMID:22401268
database_cross_reference: Reaxys:1921286
database_cross_reference: Wikipedia:Phosphoric_Acid
has exact synonym: Phosphoric acid
has exact synonym: phosphoric acid
has exact synonym: tetraoxophosphoric acid
has exact synonym: trihydrogen tetraoxophosphate(3-)
has exact synonym: trihydroxidooxidophosphorus
has_obo_namespace: chebi_ontology
has_related_synonym: H3PO4
has_related_synonym: Orthophosphoric acid
has_related_synonym: Phosphate
has_related_synonym: Phosphorsaeure
has_related_synonym: Phosphorsaeureloesungen
has_related_synonym: [PO(OH)3]
has_related_synonym: acide phosphorique
has_related_synonym: acidum phosphoricum
has_related_synonym: orthophosphoric acid
id: CHEBI:26078
in subset: 3 STAR

phosphoric acid derivative
type: Class
subclass of: CHEBI_36359
subclass of: Restriction
  on property: has functional parent
  some values from: phosphoric acid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26079
in subset: 1 STAR

phosphorus molecular entity
type: Class
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: phosphorus atom
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: phosphorus molecular entities
id: CHEBI:26082
in subset: 3 STAR

piperazines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38101
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26144
in subset: 3 STAR

piperidine alkaloid
type: Class
subclass of: alkaloid
subclass of: piperidines
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: piperidine alkaloids
id: CHEBI:26147
in subset: 3 STAR

piperidines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38101
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26151
in subset: 3 STAR

plant growth regulator
type: Class
subclass of: CHEBI_39317
definition: A chemical, natural or artificial, that can affect the rate of growth of a plant.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: plant growth regulators
id: CHEBI:26155
in subset: 3 STAR

polar amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_62031
definition: Any amino acid whose side chain is capable of forming one or more hydrogen bonds.
imported from: chebi.owl
charge: 0
formula: C2H4NO2R
mass: 74.059
monoisotopicmass: 74.02420
smiles: OC(C(*)N)=O
has_alternative_id: CHEBI:8283
database_cross_reference: MetaCyc:Polar-amino-acids
database_cross_reference: PMID:12016058
has exact synonym: polar amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: polar amino acids
has_related_synonym: polar amino-acid
has_related_synonym: polar amino-acids
id: CHEBI:26167
in subset: 3 STAR

polyether antibiotic
type: Class
subclass of: organooxygen heterocyclic antibiotic
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26179
in subset: 1 STAR

polyketide
type: Class
subclass of: ketone
subclass of: CHEBI_36963
definition: Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides.
definition: Natural compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: polyketide
has_obo_namespace: chebi_ontology
has_related_synonym: polyketides
id: CHEBI:26188
in subset: 3 STAR

polyol
type: Class
subclass of: alcohol
subclass of: organic hydroxy compound
definition: A compound that contains three or more hydroxyl groups.
definition: A compound that contains two or more hydroxy groups.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: polyols
id: CHEBI:26191
in subset: 3 STAR

polyphenol
type: Class
subclass of: phenols
definition: Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group.
imported from: chebi.owl
database_cross_reference: Wikipedia:Polyphenol
has_obo_namespace: chebi_ontology
has_related_synonym: polyphenols
id: CHEBI:26195
in subset: 3 STAR

polyprenyl group
type: Class
subclass of: prenyl groups
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26201
in subset: 1 STAR

prenyl groups
type: Class
subclass of: hydrocarbyl group
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26249
in subset: 1 STAR

proline
type: Class
subclass of: alpha-amino acid
subclass of: CHEBI_38260
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: prolinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: prolinium
definition: An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.
imported from: chebi.owl
charge: 0
formula: C5H9NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
inchikey: ONIBWKKTOPOVIA-UHFFFAOYSA-N
mass: 115.13050
monoisotopicmass: 115.06333
smiles: OC(=O)C1CCCN1
database_cross_reference: Beilstein:80809
database_cross_reference: CAS:609-36-9
database_cross_reference: Gmelin:26927
database_cross_reference: KEGG:C16435
database_cross_reference: PMID:16534801
database_cross_reference: PMID:21400017
database_cross_reference: PMID:21903295
database_cross_reference: PMID:22264337
database_cross_reference: PMID:22280966
database_cross_reference: PMID:22770225
database_cross_reference: Reaxys:80809
database_cross_reference: Wikipedia:Proline
has exact synonym: proline
has_obo_namespace: chebi_ontology
has_related_synonym: DL-Proline
has_related_synonym: Hpro
has_related_synonym: Prolin
has_related_synonym: prolina
has_related_synonym: pyrrolidine-2-carboxylic acid
id: CHEBI:26271
in subset: 3 STAR

proline derivative
type: Class
subclass of: CHEBI_83821
subclass of: Restriction
  on property: has functional parent
  some values from: proline
definition: An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: proline derivatives
id: CHEBI:26273
in subset: 3 STAR

propane-1,3-diols
type: Class
subclass of: propanediol
definition: Any propanediol bearing hydroxy groups at positions 1 and 3.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26287
in subset: 3 STAR

propanediol
type: Class
subclass of: glycol
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26288
in subset: 1 STAR

pteridines
type: Class
subclass of: organic heterobicyclic compound
subclass of: heteroarene
subclass of: CHEBI_38101
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26373
in subset: 3 STAR

pterins
type: Class
subclass of: pteridines
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26375
in subset: 3 STAR

purine nucleobase
type: Class
subclass of: nucleobase
subclass of: purines
definition: A nucleobase whose skeleton is derived from purine.
imported from: chebi.owl
charge: 0
formula: C5H3N4R2
mass: 119.104
monoisotopicmass: 119.03577
smiles: C1(NC(=NC=2NC=NC12)*)=*
database_cross_reference: KEGG:C15587
has exact synonym: purine nucleobase
has_obo_namespace: chebi_ontology
has_related_synonym: a purine nucleobase
has_related_synonym: purine bases
has_related_synonym: purine nucleobases
id: CHEBI:26386
in subset: 3 STAR

purines
type: Class
subclass of: CHEBI_35875
definition: A class of imidazopyrimidines that consists of purine and its substituted derivatives.
definition: Any compound containing purine as part of its structure.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C5N4R7
mass: 116.080
monoisotopicmass: 116.01230
has_alternative_id: CHEBI:13678
has_obo_namespace: chebi_ontology
id: CHEBI:26401
in subset: 3 STAR

pyrans
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38104
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26407
in subset: 3 STAR

pyrazoles
type: Class
subclass of: diazole
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26410
in subset: 3 STAR

pyridines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38101
definition: Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26421
in subset: 3 STAR

pyrimidine nucleobase
type: Class
subclass of: nucleobase
subclass of: CHEBI_39447
definition: A nucleobase whose skeleton is derived from pyrimidine.
imported from: chebi.owl
charge: 0
formula: C4HN2R4
mass: 77.064
monoisotopicmass: 77.01397
smiles: N1C(=C(C(=NC1=*)*)*)*
has exact synonym: pyrimidine nucleobase
has_obo_namespace: chebi_ontology
has_related_synonym: a pyrimidine nucleobase
has_related_synonym: pyrimidine bases
has_related_synonym: pyrimidine nucleobases
id: CHEBI:26432
in subset: 3 STAR

pyrimidine nucleoside
type: Class
subclass of: nucleoside
subclass of: CHEBI_39447
imported from: chebi.owl
imported from: dron.owl
database_cross_reference: KEGG:C03169
has_obo_namespace: chebi_ontology
has_related_synonym: N-D-Ribosylpyrimidine
has_related_synonym: pyrimidine nucleosides
id: CHEBI:26440
in subset: 3 STAR

pyruvate family amino acid
type: Class
subclass of: L-alpha-amino acid
subclass of: CHEBI_83813
definition: An L-alpha-amino acid which is biosynthesised from pyruvate (i.e. alanine, valine, and leucine). A closed class.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: pyruvate family amino acids
id: CHEBI:26463
in subset: 3 STAR

quaternary nitrogen compound
type: Class
subclass of: organonitrogen compound
subclass of: Restriction
  on property: has part
  some values from: quaternary ammonium ion
definition: A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26469
in subset: 3 STAR

quinoline alkaloid
type: Class
subclass of: alkaloid
subclass of: quinolines
imported from: dron.owl
has_related_synonym: quinoline alkaloids
id: CHEBI:26509

quinolines
type: Class
subclass of: organic heterobicyclic compound
subclass of: organic aromatic compound
subclass of: CHEBI_38101
definition: A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26513
in subset: 3 STAR

rhamnoside
type: Class
subclass of: deoxy hexoside
imported from: chebi.owl
has exact synonym: rhamnoside
has_obo_namespace: chebi_ontology
has_related_synonym: rhamnosides
id: CHEBI:26547
in subset: 3 STAR

saponin
type: Class
subclass of: glycoside
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has functional parent
  some values from: sapogenin
definition: A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species.
imported from: chebi.owl
has_alternative_id: CHEBI:60583
has_obo_namespace: chebi_ontology
has_related_synonym: sapogenin glycoside
has_related_synonym: sapogenin glycosides
has_related_synonym: saponins
id: CHEBI:26605
in subset: 3 STAR

sapogenin
type: Class
subclass of: CHEBI_51958
definition: Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids.
imported from: chebi.owl
has exact synonym: sapogenin
has_obo_namespace: chebi_ontology
has_related_synonym: sapogenins
id: CHEBI:26606
in subset: 3 STAR

saturated fatty acid
type: Class
subclass of: fatty acid
definition: Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess.
imported from: chebi.owl
database_cross_reference: PMID:16492686
database_cross_reference: PMID:19763019
database_cross_reference: PMID:20237329
has exact synonym: saturated fatty acid
has_obo_namespace: chebi_ontology
has_related_synonym: SFA
has_related_synonym: SFAs
has_related_synonym: saturated fatty acids
id: CHEBI:26607
in subset: 3 STAR

serine derivative
type: Class
subclass of: CHEBI_83821
subclass of: Restriction
  on property: has functional parent
  some values from: serine
definition: An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: serine derivatives
id: CHEBI:26649
in subset: 3 STAR

serine family amino acid
type: Class
subclass of: L-alpha-amino acid
subclass of: CHEBI_83813
definition: An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class.
imported from: chebi.owl
database_cross_reference: PMID:20709681
has_obo_namespace: chebi_ontology
has_related_synonym: 3-phosphoglycerate family amino acid
has_related_synonym: 3-phosphoglycerate family amino acids
has_related_synonym: serine family amino acids
id: CHEBI:26650
in subset: 3 STAR

short-chain fatty acid
type: Class
subclass of: fatty acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_58951
definition: An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid.
imported from: chebi.owl
charge: 0
formula: CH2OR
mass: 45.017
monoisotopicmass: 44.99765
smiles: OC([*])=O
database_cross_reference: PMID:16633129
database_cross_reference: PMID:16870803
database_cross_reference: PMID:18203540
database_cross_reference: PMID:20148677
has_obo_namespace: chebi_ontology
has_related_synonym: SCFA
has_related_synonym: SCFAs
has_related_synonym: short-chain fatty acids
id: CHEBI:26666
in subset: 3 STAR

amodiaquine
type: Class
subclass of: phenols
subclass of: CHEBI_36683
subclass of: CHEBI_36709
subclass of: CHEBI_50995
subclass of: CHEBI_50996
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P50135
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: EC 2.1.1.8 (histamine N-methyltransferase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: non-steroidal anti-inflammatory drug
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38068
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50266
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88188
subclass of: Restriction
  on property: is conjugate base of
  some values from: amodiaquine(1+)
definition: A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
definition source: PMID: 32366720; PMID: 30700611
definition source: https://www.drugbank.ca/drugs/DB00613
imported from: chebi.owl
charge: 0
formula: C20H22ClN3O
inchi: InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)
inchikey: OVCDSSHSILBFBN-UHFFFAOYSA-N
mass: 355.86100
monoisotopicmass: 355.14514
smiles: CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
database_cross_reference: Beilstein:300962
database_cross_reference: CAS:86-42-0
database_cross_reference: DrugBank:DB00613
database_cross_reference: Drug_Central:186
database_cross_reference: KEGG:C07626
database_cross_reference: KEGG:D02922
database_cross_reference: LINCS:LSM-4042
database_cross_reference: PDBeChem:CQA
database_cross_reference: PMID:11044276
database_cross_reference: PMID:11971651
database_cross_reference: PMID:17046445
database_cross_reference: PMID:17222819
database_cross_reference: PMID:18419816
database_cross_reference: PMID:18855526
database_cross_reference: PMID:19024339
database_cross_reference: PMID:19245687
database_cross_reference: PMID:26206402
database_cross_reference: PMID:26597254
database_cross_reference: PMID:26647924
database_cross_reference: PMID:26735991
database_cross_reference: PMID:26851641
database_cross_reference: PMID:26900802
database_cross_reference: PMID:26930583
database_cross_reference: PMID:27031231
database_cross_reference: PMID:8885219
database_cross_reference: Patent:US2474821
database_cross_reference: Reaxys:300962
database_cross_reference: Wikipedia:Amodiaquine
has exact synonym: 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
has exact synonym: Amodiaquine
has_obo_namespace: chebi_ontology
has_related_synonym: amodiaquina
has_related_synonym: amodiaquine
has_related_synonym: amodiaquinum
id: CHEBI:2674
in subset: 3 STAR

steroid hormone
type: Class
subclass of: steroid
subclass of: Restriction
  on property: has role
  some values from: hormone
definition: Any steroid that acts as hormone.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Steroidhormon
has_related_synonym: Steroidhormone
has_related_synonym: hormona esteroide
has_related_synonym: hormonas esteroideas
has_related_synonym: hormone steroide
has_related_synonym: hormones steroides
has_related_synonym: steroid hormones
id: CHEBI:26764
in subset: 3 STAR

steroid lactone
type: Class
subclass of: lactone
subclass of: steroid
imported from: chebi.owl
database_cross_reference: KEGG:C15507
has_obo_namespace: chebi_ontology
has_related_synonym: steroid lactones
id: CHEBI:26766
in subset: 3 STAR

steroid alkaloid
type: Class
subclass of: alkaloid
subclass of: steroid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: steroidal alkaloids
id: CHEBI:26767
in subset: 3 STAR

stilbene
type: Class
subclass of: benzenes
subclass of: CHEBI_78840
imported from: chebi.owl
charge: 0
formula: C14H12
inchi: InChI=1S/C14H12/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-12H
inchikey: PJANXHGTPQOBST-UHFFFAOYSA-N
mass: 180.24508
monoisotopicmass: 180.09390
smiles: [H]C(=C([H])c1ccccc1)c1ccccc1
database_cross_reference: Beilstein:1904445
database_cross_reference: CAS:588-59-0
database_cross_reference: Gmelin:67845
database_cross_reference: Wikipedia:Stilbene
has exact synonym: 1,1'-(ethene-1,2-diyl)dibenzene
has exact synonym: stilbene
has_obo_namespace: chebi_ontology
has_related_synonym: 1,1'-(1,2-ethenediyl)bis[benzene]
has_related_synonym: 1,1'-(1,2-ethenediyl)bisbenzene
has_related_synonym: 1,1'-(1,2-ethenediyl)dibenzene
has_related_synonym: 1,1'-ethene-1,2-diyldibenzene
has_related_synonym: 1,2-diphenylethylene
has_related_synonym: alpha,beta-diphenylethylene
id: CHEBI:26775
in subset: 3 STAR

stilbenoid
type: Class
subclass of: organic aromatic compound
subclass of: CHEBI_78840
definition: Any olefinic compound characterised by a 1,2-diphenylethylene backbone.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: stilbenes
has_related_synonym: stilbenoids
id: CHEBI:26776
in subset: 3 STAR

sulfide
type: Class
subclass of: sulfur molecular entity
definition: Any sulfur molecular entity that involves either covalently bonded or anionic sulfur.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: sulphides
id: CHEBI:26822
in subset: 3 STAR

sulfonium compound
type: Class
subclass of: sulfur molecular entity
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26830
in subset: 1 STAR

sulfur atom
type: Class
subclass of: nonmetal atom
subclass of: chalcogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
imported from: chebi.owl
charge: 0
formula: S
inchi: InChI=1S/S
inchikey: NINIDFKCEFEMDL-UHFFFAOYSA-N
mass: 32.06600
monoisotopicmass: 31.97207
smiles: [S]
database_cross_reference: CAS:7704-34-9
database_cross_reference: KEGG:C00087
database_cross_reference: KEGG:D06527
database_cross_reference: PPDB:605
database_cross_reference: WebElements:S
has exact synonym: sulfur
has_obo_namespace: chebi_ontology
has_related_synonym: 16S
has_related_synonym: Elemental sulfur
has_related_synonym: S
has_related_synonym: Schwefel
has_related_synonym: azufre
has_related_synonym: soufre
has_related_synonym: sulfur
has_related_synonym: sulphur
has_related_synonym: theion
id: CHEBI:26833
in subset: 3 STAR

sulfur-containing amino acid
type: Class
subclass of: sulfur-containing carboxylic acid
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_63470
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur-containing amino acids
id: CHEBI:26834
in subset: 3 STAR

sulfur molecular entity
type: Class
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has part
  some values from: sulfur atom
imported from: chebi.owl
imported from: dron.owl
has exact synonym: sulfur molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur molecular entities
id: CHEBI:26835
in subset: 3 STAR

terpene ketone
type: Class
subclass of: ketone
subclass of: terpenoid
definition: Any terpenoid which contains a keto group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26872
in subset: 3 STAR

terpenoid
type: Class
subclass of: isoprenoid
subclass of: Restriction
  on property: has parent hydride
  some values from: terpene
definition: Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.
imported from: chebi.owl
database_cross_reference: Wikipedia:Terpenoid
has exact synonym: Terpenoid
has exact synonym: terpenoids
has_obo_namespace: chebi_ontology
has_related_synonym: terpenoide
has_related_synonym: terpenoides
id: CHEBI:26873
in subset: 3 STAR

tertiary alcohol
type: Class
subclass of: alcohol
definition: A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it.
imported from: chebi.owl
charge: 0
formula: C4H7OR3
mass: 71.09780
monoisotopicmass: 71.04969
smiles: OC(C[*])(C[*])C[*]
has exact synonym: tertiary alcohol
has_obo_namespace: chebi_ontology
has_related_synonym: tertiary alcohols
id: CHEBI:26878
in subset: 3 STAR

tetrahydrofolic acid
type: Class
subclass of: CHEBI_37445
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_67016
definition: A group of heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more L-glutamic acid units.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: tetrahydrofolate
has_related_synonym: tetrahydrofolates
has_related_synonym: tetrahydrofolic acids
id: CHEBI:26907
in subset: 3 STAR

oxolanes
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38104
definition: Any oxacycle having an oxolane (tetrahydrofuran) skeleton.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26912
in subset: 3 STAR

thiophenes
type: Class
subclass of: CHEBI_38106
definition: Compounds containing at least one thiophene ring.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:26961
in subset: 3 STAR

organic heterotricyclic compound
type: Class
subclass of: CHEBI_36688
subclass of: CHEBI_38166
subclass of: CHEBI_51959
definition: An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: heterotricyclic compounds
has_related_synonym: organic heterotricyclic compounds
id: CHEBI:26979
in subset: 3 STAR

threonine
type: Class
subclass of: polar amino acid
subclass of: CHEBI_38263
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50341
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: threoninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: threoninium
definition: An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group.
imported from: chebi.owl
charge: 0
formula: C4H9NO3
mass: 119.119
monoisotopicmass: 119.05824
database_cross_reference: Beilstein:8204750
database_cross_reference: CAS:80-68-2
database_cross_reference: PMID:11379295
database_cross_reference: PMID:15221503
database_cross_reference: PMID:22264337
database_cross_reference: Wikipedia:Threonine
has exact synonym: threonine
has_obo_namespace: chebi_ontology
has_related_synonym: Threonin
id: CHEBI:26986
in subset: 3 STAR

toluenes
type: Class
subclass of: benzenes
definition: Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:27024
in subset: 3 STAR

toxin
type: Class
subclass of: metabolite
subclass of: CHEBI_64909
definition: Poisonous substance produced by a biological organism such as a microbe, animal or plant.
imported from: chebi.owl
database_cross_reference: Wikipedia:Toxin
has exact synonym: toxin
has_obo_namespace: chebi_ontology
has_related_synonym: toxins
id: CHEBI:27026
in subset: 3 STAR

micronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
imported from: chebi.owl
database_cross_reference: Wikipedia:Micronutrient
has_obo_namespace: chebi_ontology
has_related_synonym: micronutrients
has_related_synonym: trace elements
id: CHEBI:27027
in subset: 3 STAR

tricarboxylic acid trianion
type: Class
subclass of: CHEBI_35753
subclass of: CHEBI_38717
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: tricarboxylate
has_related_synonym: tricarboxylates
has_related_synonym: tricarboxylic acid trianions
id: CHEBI:27092
in subset: 3 STAR

tricarboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_35753
definition: An oxoacid containing three carboxy groups.
imported from: chebi.owl
charge: 0
formula: C3H3O6R
mass: 135.052
monoisotopicmass: 134.99296
database_cross_reference: Wikipedia:Tricarboxylic_acid
has_obo_namespace: chebi_ontology
has_related_synonym: Tricarbonsaeure
has_related_synonym: Trikarbonsaeure
has_related_synonym: tricarboxylic acids
id: CHEBI:27093
in subset: 3 STAR

trichlorobenzene
type: Class
subclass of: chlorobenzenes
definition: Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions.
imported from: chebi.owl
charge: 0
formula: C6H3Cl3
mass: 181.447
monoisotopicmass: 179.93003
database_cross_reference: Wikipedia:Trichlorobenzene
has exact synonym: trichlorobenzene
has_obo_namespace: chebi_ontology
has_related_synonym: Trichlorbenzol
id: CHEBI:27096
in subset: 3 STAR

trihydroxyflavone
type: Class
subclass of: hydroxyflavone
definition: Any hydroxyflavone carrying three hydroxy groups at unspecified positions.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: trihydroxyflavones
id: CHEBI:27116
in subset: 3 STAR

organic heterobicyclic compound
type: Class
subclass of: organic heterocyclic compound
subclass of: heterobicyclic compound
subclass of: CHEBI_38166
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: heterobicyclic compounds
has_related_synonym: organic heterobicyclic compounds
id: CHEBI:27171
in subset: 3 STAR

univalent carboacyl group
type: Class
subclass of: CHEBI_37838
definition: A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: univalent acyl group
has_related_synonym: univalent carboacyl groups
has_related_synonym: univalent carboxylic acyl groups
id: CHEBI:27207
in subset: 3 STAR

unsaturated fatty acid
type: Class
subclass of: fatty acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: unsaturated fatty acid anion
definition: Any fatty acid containing at least one C=C or C#C bond.
imported from: chebi.owl
database_cross_reference: LIPID_MAPS_class:LMFA0103
database_cross_reference: PMID:5322381
has_obo_namespace: chebi_ontology
has_related_synonym: alkene acid
has_related_synonym: olefinic acid
has_related_synonym: unsaturated fatty acids
id: CHEBI:27208
in subset: 3 STAR

valine
type: Class
subclass of: branched-chain amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: isopropyl group
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: valinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: valinium
definition: A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group.
imported from: chebi.owl
charge: 0
formula: C5H11NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)
inchikey: KZSNJWFQEVHDMF-UHFFFAOYSA-N
mass: 117.14638
monoisotopicmass: 117.07898
smiles: CC(C)C(N)C(O)=O
database_cross_reference: Beilstein:506689
database_cross_reference: CAS:516-06-3
database_cross_reference: Gmelin:49877
database_cross_reference: KEGG:C16436
database_cross_reference: PMID:17190852
database_cross_reference: PMID:22770225
database_cross_reference: Reaxys:506689
database_cross_reference: Wikipedia:Valine
has exact synonym: valine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-methylbutanoic acid
has_related_synonym: DL-valine
has_related_synonym: Hval
has_related_synonym: Valin
has_related_synonym: valina
id: CHEBI:27266
in subset: 3 STAR

valine derivative
type: Class
subclass of: modified amino acid
subclass of: CHEBI_83821
subclass of: Restriction
  on property: has functional parent
  some values from: valine
definition: An amino acid derivative resulting from reaction of valine at the amino group or the carboxy group, or from the replacement of any hydrogen of valine by a heteroatom. The definition normally excludes peptides containing valine residues.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:27267
in subset: 3 STAR

water-soluble vitamin (role)
type: Class
subclass of: vitamin (role)
definition: Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: wasserloesliche Vitamine
has_related_synonym: water-soluble vitamin
has_related_synonym: water-soluble vitamins
id: CHEBI:27314
in subset: 3 STAR

yohimban alkaloid
type: Class
subclass of: CHEBI_38958
subclass of: CHEBI_65323
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
id: CHEBI:27358
in subset: 1 STAR

zinc molecular entity
type: Class
subclass of: zinc group molecular entity
imported from: dron.owl
has_related_synonym: zinc compounds
has_related_synonym: zinc molecular entities
id: CHEBI:27364

zwitterion
type: Class
subclass of: CHEBI_51151
definition: A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
imported from: chebi.owl
has exact synonym: zwitterion
has exact synonym: zwitterions
has_obo_namespace: chebi_ontology
has_related_synonym: compose zwitterionique
has_related_synonym: compuestos zwitterionicos
has_related_synonym: zwitteriones
has_related_synonym: zwitterionic compounds
id: CHEBI:27369
in subset: 3 STAR

methanesulfonic acid
type: Class
subclass of: CHEBI_47901
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methanesulfonate
definition: An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl.
imported from: chebi.owl
charge: 0
formula: CH4O3S
inchi: InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)
inchikey: AFVFQIVMOAPDHO-UHFFFAOYSA-N
mass: 96.10666
monoisotopicmass: 95.98812
smiles: CS(O)(=O)=O
has_alternative_id: CHEBI:6813
database_cross_reference: Beilstein:1446024
database_cross_reference: CAS:75-75-2
database_cross_reference: Gmelin:1681
database_cross_reference: KEGG:C11145
database_cross_reference: MetaCyc:CPD-3746
database_cross_reference: PMID:24304088
database_cross_reference: PMID:24593036
database_cross_reference: Reaxys:1446024
database_cross_reference: Wikipedia:Methanesulfonic_acid
has exact synonym: Methanesulfonic acid
has exact synonym: methanesulfonic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Methansulfonsaeure
has_related_synonym: methylsulfonic acid
id: CHEBI:27376
in subset: 3 STAR

D-valine
type: Class
subclass of: D-alpha-amino acid
subclass of: valine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-valinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-valinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-valine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_74338
definition: The D-enantiomer of valine.
imported from: chebi.owl
charge: 0
formula: C5H11NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
inchikey: KZSNJWFQEVHDMF-SCSAIBSYSA-N
mass: 117.14638
monoisotopicmass: 117.07898
smiles: CC(C)[C@@H](N)C(O)=O
has_alternative_id: CHEBI:21112
has_alternative_id: CHEBI:4261
database_cross_reference: Beilstein:1721135
database_cross_reference: CAS:640-68-6
database_cross_reference: Gmelin:82413
database_cross_reference: KEGG:C06417
database_cross_reference: MetaCyc:CPD-3642
database_cross_reference: PDBeChem:DVA
database_cross_reference: PMID:13465080
database_cross_reference: PMID:23085840
database_cross_reference: PMID:236834
database_cross_reference: PMID:7118128
database_cross_reference: Reaxys:1721135
has exact synonym: D-Valine
has exact synonym: D-valine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-methylbutanoic acid
has_related_synonym: (R)-2-Amino-3-methylbutyric acid
has_related_synonym: (R)-valine
has_related_synonym: D-Valin
has_related_synonym: DVA
id: CHEBI:27477
in subset: 3 STAR

oxirane
type: Class
subclass of: gas molecular entity
subclass of: CHEBI_36389
subclass of: CHEBI_38104
subclass of: Restriction
  on property: has role
  some values from: mutagen
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50904
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
definition: A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.
imported from: chebi.owl
charge: 0
formula: C2H4O
inchi: InChI=1S/C2H4O/c1-2-3-1/h1-2H2
inchikey: IAYPIBMASNFSPL-UHFFFAOYSA-N
mass: 44.05256
monoisotopicmass: 44.02621
smiles: C1CO1
has_alternative_id: CHEBI:24001
has_alternative_id: CHEBI:4900
database_cross_reference: Beilstein:102378
database_cross_reference: CAS:75-21-8
database_cross_reference: Gmelin:676
database_cross_reference: HMDB:HMDB0031305
database_cross_reference: KEGG:C06548
database_cross_reference: KEGG:D03474
database_cross_reference: PMID:11437638
database_cross_reference: PMID:24313866
database_cross_reference: PMID:24882394
database_cross_reference: PMID:25005741
database_cross_reference: PMID:3932500
database_cross_reference: Reaxys:102378
database_cross_reference: UM-BBD_compID:c0527
database_cross_reference: Wikipedia:Oxirane
has exact synonym: oxirane
has_obo_namespace: chebi_ontology
has_related_synonym: 1,2-Epoxyaethan
has_related_synonym: 1,2-epoxyethane
has_related_synonym: Aethylenoxid
has_related_synonym: Amprolene
has_related_synonym: Anprolene
has_related_synonym: Anproline
has_related_synonym: Dihydrooxirene
has_related_synonym: Dimethylene oxide
has_related_synonym: ETO
has_related_synonym: Ethylene oxide
has_related_synonym: Oxacyclopropane
has_related_synonym: Oxane
has_related_synonym: Oxidoethane
has_related_synonym: Oxyfume
has_related_synonym: epoxyethane
has_related_synonym: ethene oxide
has_related_synonym: oxyde d'ethylene
id: CHEBI:27561
in subset: 3 STAR

histidine
type: Class
subclass of: imidazoles
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: aromatic amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50338
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: histidinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: histidinium(1+)
definition: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.
imported from: chebi.owl
charge: 0
formula: C6H9N3O2
inchi: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)
inchikey: HNDVDQJCIGZPNO-UHFFFAOYSA-N
mass: 155.15468
monoisotopicmass: 155.06948
smiles: NC(Cc1c[nH]cn1)C(O)=O
has_alternative_id: CHEBI:24598
has_alternative_id: CHEBI:43118
has_alternative_id: CHEBI:5733
database_cross_reference: Beilstein:84087
database_cross_reference: CAS:4998-57-6
database_cross_reference: Gmelin:3656
database_cross_reference: KEGG:C00768
database_cross_reference: KNApSAcK:C00001363
database_cross_reference: PMID:17190852
database_cross_reference: PMID:22264337
database_cross_reference: PMID:22770225
database_cross_reference: PMID:29286160
database_cross_reference: Reaxys:84087
database_cross_reference: Wikipedia:Histidine
has exact synonym: 2-amino-3-(1H-imidazol-4-yl)propanoic acid
has exact synonym: Histidine
has exact synonym: histidine
has_obo_namespace: chebi_ontology
has_related_synonym: DL-Histidine
has_related_synonym: Histidin
has_related_synonym: alpha-Amino-1H-imidazole-4-propionic acid
has_related_synonym: histidina
id: CHEBI:27570
in subset: 3 STAR

phosphoramidate ester
type: Class
subclass of: phosphoramide
subclass of: CHEBI_37734
definition: A phosphoric ester (phosphate) that has an NR2 instead of an OH group.
imported from: chebi.owl
has_alternative_id: CHEBI:26050
has_alternative_id: CHEBI:37718
has_alternative_id: CHEBI:8144
database_cross_reference: KEGG:C01976
has_obo_namespace: chebi_ontology
has_related_synonym: Phosphoamide
has_related_synonym: phosphoramidate esters
id: CHEBI:27577
in subset: 3 STAR

carbon atom
type: Class
subclass of: nonmetal atom
subclass of: carbon group element atom
subclass of: Restriction
  on property: has role
  some values from: macronutrient
imported from: chebi.owl
charge: 0
formula: C
inchi: InChI=1S/C
inchikey: OKTJSMMVPCPJKN-UHFFFAOYSA-N
mass: 12.01070
monoisotopicmass: 12.00000
smiles: [C]
has_alternative_id: CHEBI:23009
has_alternative_id: CHEBI:3399
database_cross_reference: CAS:7440-44-0
database_cross_reference: KEGG:C06265
database_cross_reference: WebElements:C
has exact synonym: carbon
has_obo_namespace: chebi_ontology
has_related_synonym: 6C
has_related_synonym: C
has_related_synonym: Carbon
has_related_synonym: Kohlenstoff
has_related_synonym: carbon
has_related_synonym: carbone
has_related_synonym: carbonium
has_related_synonym: carbono
id: CHEBI:27594
in subset: 3 STAR

monensin A
type: Class
subclass of: monocarboxylic acid
subclass of: polyether antibiotic
subclass of: CHEBI_59780
subclass of: CHEBI_72600
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: ionophore
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35718
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35818
definition: A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle.
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C36H62O11
inchi: InChI=1S/C36H62O11/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40)/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35+,36-/m0/s1
inchikey: GAOZTHIDHYLHMS-KEOBGNEYSA-N
mass: 670.87090
monoisotopicmass: 670.42921
has_alternative_id: CHEBI:25376
has_alternative_id: CHEBI:6973
database_cross_reference: CAS:17090-79-8
database_cross_reference: KEGG:C06693
database_cross_reference: KEGG:D08228
database_cross_reference: LINCS:LSM-5659
database_cross_reference: PMID:21215424
database_cross_reference: Reaxys:1633130
has exact synonym: (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
has exact synonym: Monensin A
has_obo_namespace: chebi_ontology
has_related_synonym: Monensin
has_related_synonym: monensic acid
has_related_synonym: monensin
has_related_synonym: monensina
has_related_synonym: monensinum
id: CHEBI:27617
in subset: 3 STAR

cycloheximide
type: Class
subclass of: dicarboximide
subclass of: secondary alcohol
subclass of: CHEBI 3992
subclass of: CHEBI_48589
subclass of: CHEBI_49318
subclass of: CHEBI_87114
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: ferroptosis inhibitor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48001
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63726
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI 5435
definition: A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C15H23NO4
inchi: InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
inchikey: YPHMISFOHDHNIV-FSZOTQKASA-N
mass: 281.352
monoisotopicmass: 281.16271
has_alternative_id: CHEBI:23484
has_alternative_id: CHEBI:4015
database_cross_reference: Beilstein:88868
database_cross_reference: CAS:66-81-9
database_cross_reference: KEGG:C06685
database_cross_reference: KEGG:D03625
database_cross_reference: KNApSAcK:C00047211
database_cross_reference: LINCS:LSM-2791
database_cross_reference: PDBeChem:3HE
database_cross_reference: PMID:11972861
database_cross_reference: PMID:16659174
database_cross_reference: PMID:25209664
database_cross_reference: PMID:26715760
database_cross_reference: PMID:27192630
database_cross_reference: PMID:27665925
database_cross_reference: PMID:30154175
database_cross_reference: PMID:30916348
database_cross_reference: PMID:32299921
database_cross_reference: PMID:33101237
database_cross_reference: PPDB:1680
database_cross_reference: Reaxys:88868
database_cross_reference: Wikipedia:Cycloheximide
has exact synonym: 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
has exact synonym: Cycloheximide
has exact synonym: cycloheximide
has_obo_namespace: chebi_ontology
has_related_synonym: 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide
has_related_synonym: Cycloheximid
has_related_synonym: Zykloheximid
has_related_synonym: cicloheximida
has_related_synonym: cicloheximide
has_related_synonym: cicloheximidum
has_related_synonym: naramycin
has_related_synonym: naramycin A
id: CHEBI:27641
in subset: 3 STAR

alpha-L-rhamnoside
type: Class
subclass of: rhamnoside
imported from: chebi.owl
charge: 0
formula: C6H11O5R
mass: 163.14850
monoisotopicmass: 163.06065
has_alternative_id: CHEBI:10294
has_alternative_id: CHEBI:22426
database_cross_reference: KEGG:C02757
has exact synonym: 6-deoxy-alpha-L-mannopyranoside
has exact synonym: alpha-L-Rhamnoside
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-L-rhamnosides
id: CHEBI:27848
in subset: 3 STAR

tryptophan
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: aromatic amino acid
subclass of: CHEBI_38631
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50337
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tryptophanate
subclass of: Restriction
  on property: is conjugate base of
  some values from: tryptophanium
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_64554
definition: An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.
imported from: chebi.owl
charge: 0
formula: C11H12N2O2
inchi: InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)
inchikey: QIVBCDIJIAJPQS-UHFFFAOYSA-N
mass: 204.22526
monoisotopicmass: 204.08988
smiles: NC(Cc1c[nH]c2ccccc12)C(O)=O
has_alternative_id: CHEBI:27163
has_alternative_id: CHEBI:9769
database_cross_reference: Beilstein:86196
database_cross_reference: CAS:54-12-6
database_cross_reference: Gmelin:4532
database_cross_reference: KEGG:C00806
database_cross_reference: KNApSAcK:C00001396
database_cross_reference: LINCS:LSM-36836
database_cross_reference: PMID:17439666
database_cross_reference: PMID:22264337
database_cross_reference: Reaxys:86196
database_cross_reference: Wikipedia:Tryptophan
has exact synonym: Tryptophan
has exact synonym: tryptophan
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-(1H-indol-3-yl)propanoic acid
has_related_synonym: Htrp
has_related_synonym: Trp
has_related_synonym: W
has_related_synonym: alpha-Amino-beta-(3-indolyl)-propionic acid
has_related_synonym: alpha-amino-beta-3-indolepropionic acid
has_related_synonym: beta-3-indolylalanine
has_related_synonym: triptofano
has_related_synonym: tryptophane
id: CHEBI:27897
in subset: 3 STAR

conessine
type: Class
subclass of: steroid alkaloid
subclass of: CHEBI_50996
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38068
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64176
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has functional parent
  some values from: conanine
definition: A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae.
definition source: PMID: 30918074
imported from: chebi.owl
charge: 0
formula: C24H40N2
inchi: InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
inchikey: GPLGAQQQNWMVMM-MYAJQUOBSA-N
mass: 356.58780
monoisotopicmass: 356.31915
has_alternative_id: CHEBI:23369
has_alternative_id: CHEBI:3853
database_cross_reference: Beilstein:4702160
database_cross_reference: CAS:546-06-5
database_cross_reference: KEGG:C06545
database_cross_reference: KNApSAcK:C00002243
database_cross_reference: PMID:15413865
database_cross_reference: PMID:18683917
database_cross_reference: PMID:20161899
database_cross_reference: PMID:21834632
database_cross_reference: PMID:23758861
database_cross_reference: Reaxys:4702160
database_cross_reference: Wikipedia:Conessine
has exact synonym: Conessine
has exact synonym: N,N-dimethylcon-5-enin-3beta-amine
has_obo_namespace: chebi_ontology
has_related_synonym: Conessinum
has_related_synonym: Neriine
has_related_synonym: Roquessine
id: CHEBI:27965
in subset: 3 STAR

vancomycin
type: Class
subclass of: glycopeptide
definition: A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.
imported from: chebi.owl
charge: 0
formula: C66H75Cl2N9O24
inchikey: MYPYJXKWCTUITO-LYRMYLQWSA-N
mass: 1449.25336
monoisotopicmass: 1447.43020
has_alternative_id: CHEBI:27276
has_alternative_id: CHEBI:49941
has_alternative_id: CHEBI:9931
database_cross_reference: Beilstein:3132
database_cross_reference: CAS:1404-90-6
database_cross_reference: DrugBank:DB00512
database_cross_reference: Drug_Central:2807
database_cross_reference: KEGG:C06689
database_cross_reference: KEGG:D00212
database_cross_reference: KNApSAcK:C00016052
database_cross_reference: MetaCyc:CPD-12245
database_cross_reference: PDBeChem:VAN
database_cross_reference: PMID:11028184
database_cross_reference: PMID:11408222
database_cross_reference: PMID:11688538
database_cross_reference: PMID:11864951
database_cross_reference: PMID:11886013
database_cross_reference: PMID:11980329
database_cross_reference: PMID:12019070
database_cross_reference: PMID:12541895
database_cross_reference: PMID:12852813
database_cross_reference: PMID:13370625
database_cross_reference: PMID:13521912
database_cross_reference: PMID:14605050
database_cross_reference: PMID:14702667
database_cross_reference: PMID:15047516
database_cross_reference: PMID:15081082
database_cross_reference: PMID:15465645
database_cross_reference: PMID:15590714
database_cross_reference: PMID:15792257
database_cross_reference: PMID:16183423
database_cross_reference: PMID:16184232
database_cross_reference: PMID:16420976
database_cross_reference: PMID:16596002
database_cross_reference: PMID:16720708
database_cross_reference: PMID:17027219
database_cross_reference: PMID:17184835
database_cross_reference: PMID:17299012
database_cross_reference: PMID:17594206
database_cross_reference: PMID:18030187
database_cross_reference: PMID:18159039
database_cross_reference: PMID:18162343
database_cross_reference: PMID:18260149
database_cross_reference: PMID:18361944
database_cross_reference: PMID:18462092
database_cross_reference: PMID:18582342
database_cross_reference: PMID:18817166
database_cross_reference: PMID:18983037
database_cross_reference: PMID:19107100
database_cross_reference: PMID:19830166
database_cross_reference: PMID:20956604
database_cross_reference: PMID:21109901
database_cross_reference: PMID:21458937
database_cross_reference: PMID:21466775
database_cross_reference: PMID:21664803
database_cross_reference: PMID:21719238
database_cross_reference: PMID:21951032
database_cross_reference: PMID:22011388
database_cross_reference: PMID:22015328
database_cross_reference: PMID:22027450
database_cross_reference: PMID:22124537
database_cross_reference: Patent:US3067099
database_cross_reference: Reaxys:3132
database_cross_reference: Wikipedia:Vancomycin
has exact synonym: (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid
has exact synonym: VANCOMYCIN
has exact synonym: Vancomycin
has_obo_namespace: chebi_ontology
has_related_synonym: (1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
has_related_synonym: (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):C(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]
has_related_synonym: Vancocin

phenylalanine
type: Class
subclass of: alpha-amino acid
subclass of: aromatic amino acid
subclass of: Restriction
  on property: has part
  some values from: benzyl group
subclass of: Restriction
  on property: has role
  some values from: CHEBI_83056
subclass of: Restriction
  on property: is conjugate acid of
  some values from: phenylalaninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: phenylalaninium
definition: An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.
imported from: chebi.owl
charge: 0
formula: C9H11NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
inchikey: COLNVLDHVKWLRT-UHFFFAOYSA-N
mass: 165.18918
monoisotopicmass: 165.07898
smiles: NC(Cc1ccccc1)C(O)=O
has_alternative_id: CHEBI:25984
has_alternative_id: CHEBI:8089
database_cross_reference: Beilstein:1910407
database_cross_reference: CAS:150-30-1
database_cross_reference: Gmelin:50836
database_cross_reference: KEGG:C02057
database_cross_reference: PMID:17439666
database_cross_reference: PMID:22264337
database_cross_reference: Reaxys:1910407
database_cross_reference: Wikipedia:Phenylalanine
has exact synonym: 2-amino-3-phenylpropanoic acid
has exact synonym: Phenylalanine
has exact synonym: phenylalanine
has_obo_namespace: chebi_ontology
has_related_synonym: DL-Phenylalanine
has_related_synonym: F
has_related_synonym: PHE
has_related_synonym: Phenylalanin
has_related_synonym: alpha-Amino-beta-phenylpropionic acid
has_related_synonym: fenilalanina
id: CHEBI:28044
in subset: 3 STAR

harmine
type: Class
subclass of: CHEBI_61379
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38623
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64946
subclass of: Restriction
  on property: has parent hydride
  some values from: CHEBI 5623
definition: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7.
definition source: PMID: 30918074
imported from: chebi.owl
charge: 0
formula: C13H12N2O
inchi: InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
inchikey: BXNJHAXVSOCGBA-UHFFFAOYSA-N
mass: 212.24720
monoisotopicmass: 212.09496
smiles: COc1ccc2c(c1)[nH]c1c(C)nccc21
has_alternative_id: CHEBI:24477
has_alternative_id: CHEBI:5624
database_cross_reference: Beilstein:178813
database_cross_reference: CAS:442-51-3
database_cross_reference: DrugBank:DB07919
database_cross_reference: KEGG:C06538
database_cross_reference: KNApSAcK:C00001737
database_cross_reference: LINCS:LSM-5451
database_cross_reference: PDBeChem:HRM
database_cross_reference: PMID:11473435
database_cross_reference: PMID:22877698
database_cross_reference: Reaxys:178813
database_cross_reference: Wikipedia:Harmine
has exact synonym: 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
has exact synonym: Harmine
has_obo_namespace: chebi_ontology
has_related_synonym: 6-Methoxyharman
has_related_synonym: 7-methoxy-1-methyl-9H-beta-carboline
has_related_synonym: Banisterine
has_related_synonym: Leucoharmine
has_related_synonym: Telepathine
has_related_synonym: Yageine
has_related_synonym: Yajeine
id: CHEBI:28121
in subset: 3 STAR

pinocembrin
type: Class
subclass of: (2S)-flavan-4-one
subclass of: CHEBI_38749
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: vasodilator agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63726
definition: A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.
imported from: chebi.owl
charge: 0
formula: C15H12O4
inchi: InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
inchikey: URFCJEUYXNAHFI-ZDUSSCGKSA-N
mass: 256.25340
monoisotopicmass: 256.07356
smiles: Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccccc1
has_alternative_id: CHEBI:26139
has_alternative_id: CHEBI:69684
has_alternative_id: CHEBI:75100
has_alternative_id: CHEBI:8221
database_cross_reference: CAS:480-39-7
database_cross_reference: HMDB:HMDB0030808
database_cross_reference: KEGG:C09827
database_cross_reference: KNApSAcK:C00000992
database_cross_reference: LINCS:LSM-4126
database_cross_reference: LIPID_MAPS_instance:LMPK12140214
database_cross_reference: MetaCyc:CPD-6991
database_cross_reference: PMID:21973101
database_cross_reference: PMID:22050318
database_cross_reference: PMID:23179089
database_cross_reference: PMID:23212747
database_cross_reference: PMID:23594163
database_cross_reference: PMID:23611777
database_cross_reference: PMID:23669639
database_cross_reference: PMID:23697399
database_cross_reference: PMID:23725831
database_cross_reference: PMID:23725838
database_cross_reference: PMID:23847074
database_cross_reference: Reaxys:88951
database_cross_reference: Wikipedia:Pinocembrin
has exact synonym: (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-pinocembrin
has_related_synonym: (S)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one
has_related_synonym: (S)-5,7-dihydroxyflavanone
has_related_synonym: (S)-pinocembrin
has_related_synonym: 5,7-Dihydroxyflavanone
has_related_synonym: Dihydrochrysin
has_related_synonym: Galangin flavanone
id: CHEBI:28157
in subset: 3 STAR

D-asparagine
type: Class
subclass of: D-alpha-amino acid
subclass of: asparagine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-asparaginate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-asparaginium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-asparagine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_74337
definition: An optically active form of asparagine having D-configuration.
imported from: chebi.owl
charge: 0
formula: C4H8N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m1/s1
inchikey: DCXYFEDJOCDNAF-UWTATZPHSA-N
mass: 132.119
monoisotopicmass: 132.05349
smiles: OC([C@@H](CC(N)=O)N)=O
has_alternative_id: CHEBI:20918
has_alternative_id: CHEBI:4107
database_cross_reference: Beilstein:1723526
database_cross_reference: CAS:2058-58-4
database_cross_reference: DrugBank:DB03943
database_cross_reference: Gmelin:101784
database_cross_reference: HMDB:HMDB0033780
database_cross_reference: KEGG:C01905
database_cross_reference: MetaCyc:CPD-3633
database_cross_reference: PDBeChem:DSG
database_cross_reference: PMID:767332
database_cross_reference: Patent:CN101333175
database_cross_reference: Reaxys:1723526
database_cross_reference: YMDB:YMDB00849
has exact synonym: D-Asparagine
has exact synonym: D-asparagine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2,4-diamino-4-oxobutanoic acid
has_related_synonym: (2R)-2-amino-3-carbamoylpropanoic acid
has_related_synonym: (R)-2-amino-3-carbamoylpropanoic acid
has_related_synonym: D-2-aminosuccinamic acid
has_related_synonym: D-Asparagin
has_related_synonym: D-aspartic acid beta-amide
has_related_synonym: DSG
id: CHEBI:28159
in subset: 3 STAR

benzamide
type: Class
subclass of: benzamides
definition: An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
imported from: chebi.owl
charge: 0
formula: C7H7NO
inchi: InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
inchikey: KXDAEFPNCMNJSK-UHFFFAOYSA-N
mass: 121.13662
monoisotopicmass: 121.05276
smiles: NC(=O)c1ccccc1
has_alternative_id: CHEBI:22701
has_alternative_id: CHEBI:3021
has_alternative_id: CHEBI:46351
database_cross_reference: Beilstein:385876
database_cross_reference: CAS:55-21-0
database_cross_reference: HMDB:HMDB0004461
database_cross_reference: KEGG:C09815
database_cross_reference: PMID:20133863
database_cross_reference: Reaxys:385876
database_cross_reference: UM-BBD_compID:c0368
database_cross_reference: Wikipedia:Benzamide
has exact synonym: Benzamide
has exact synonym: benzamide
has_obo_namespace: chebi_ontology
has_related_synonym: Benzenecarboxamide
has_related_synonym: Benzoic acid amide
has_related_synonym: Benzoylamide
has_related_synonym: PhC(=O)NH2
has_related_synonym: PhC(O)NH2
has_related_synonym: Phenylcarboxamide
has_related_synonym: Phenylcarboxyamide
id: CHEBI:28179
in subset: 3 STAR

D-leucine
type: Class
subclass of: D-alpha-amino acid
subclass of: leucine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-leucinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-leucinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-leucine
subclass of: Restriction
  on property: is tautomer of
  some values from: D-leucine zwitterion
definition: The D-enantiomer of leucine.
imported from: chebi.owl
charge: 0
formula: C6H13NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1
inchikey: ROHFNLRQFUQHCH-RXMQYKEDSA-N
mass: 131.17296
monoisotopicmass: 131.09463
smiles: CC(C)C[C@@H](N)C(O)=O
has_alternative_id: CHEBI:21045
has_alternative_id: CHEBI:41908
has_alternative_id: CHEBI:4202
database_cross_reference: Beilstein:1721721
database_cross_reference: CAS:328-38-1
database_cross_reference: DrugBank:DB01746
database_cross_reference: Gmelin:82675
database_cross_reference: HMDB:HMDB0013773
database_cross_reference: KEGG:C01570
database_cross_reference: PDBeChem:DLE
database_cross_reference: PMID:15375647
database_cross_reference: PMID:21941889
database_cross_reference: PMID:24097941
database_cross_reference: Reaxys:1721721
database_cross_reference: YMDB:YMDB00997
has exact synonym: D-LEUCINE
has exact synonym: D-Leucine
has exact synonym: D-leucine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-4-methylpentanoic acid
has_related_synonym: (R)-(-)-leucine
has_related_synonym: (R)-leucine
has_related_synonym: D-2-Amino-4-methylvaleric acid
has_related_synonym: D-Leucin
has_related_synonym: D-Leuzin
has_related_synonym: DLE
id: CHEBI:28225
in subset: 3 STAR

dimethyl sulfoxide
type: Class
subclass of: volatile organic compound
subclass of: sulfoxide
definition: A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
imported from: chebi.owl
charge: 0
formula: C2H6OS
inchi: InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
inchikey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N
mass: 78.13444
monoisotopicmass: 78.01394
smiles: CS(C)=O
has_alternative_id: CHEBI:23801
has_alternative_id: CHEBI:42138
has_alternative_id: CHEBI:4612
database_cross_reference: Beilstein:506008
database_cross_reference: CAS:67-68-5
database_cross_reference: Chemspider:659
database_cross_reference: DrugBank:DB01093
database_cross_reference: Drug_Central:906
database_cross_reference: FooDB:FDB000764
database_cross_reference: Gmelin:1556
database_cross_reference: HMDB:HMDB0002151
database_cross_reference: KEGG:C11143
database_cross_reference: KEGG:D01043
database_cross_reference: KNApSAcK:C00053120
database_cross_reference: LINCS:LSM-36361
database_cross_reference: MetaCyc:DMSO
database_cross_reference: PDBeChem:DMS
database_cross_reference: PMID:10298633
database_cross_reference: PMID:11162043
database_cross_reference: PMID:11350866
database_cross_reference: PMID:11474739
database_cross_reference: PMID:12663039
database_cross_reference: PMID:15237653
database_cross_reference: PMID:15588915
database_cross_reference: PMID:15868171
database_cross_reference: PMID:16434015
database_cross_reference: PMID:16522014
database_cross_reference: PMID:19096138
database_cross_reference: PMID:19382398
database_cross_reference: PMID:19443933
database_cross_reference: PMID:20828537
database_cross_reference: PMID:21426213
database_cross_reference: PMID:22030943
database_cross_reference: PMID:22722716
database_cross_reference: PMID:22768202
database_cross_reference: PMID:22814967
database_cross_reference: PMID:23050031
database_cross_reference: PMID:23313473
database_cross_reference: PMID:28220525
database_cross_reference: PMID:29938311
database_cross_reference: PMID:31489176
database_cross_reference: PMID:3510103
database_cross_reference: PMID:3898376
database_cross_reference: PMID:3916302
database_cross_reference: PMID:4223708
database_cross_reference: PMID:4556944
database_cross_reference: PMID:4963226
database_cross_reference: PMID:6309056
database_cross_reference: PMID:6379027
database_cross_reference: Reaxys:506008
database_cross_reference: UM-BBD_compID:c0236
database_cross_reference: Wikipedia:Dimethyl_sulfoxide
has exact synonym: (methanesulfinyl)methane
has exact synonym: DIMETHYL SULFOXIDE
has exact synonym: Dimethyl sulfoxide
has exact synonym: dimethyl sulfoxide
has_obo_namespace: chebi_ontology
has_related_synonym: (CH3)2SO
has_related_synonym: DMSO
has_related_synonym: Dimethylsulfoxid
has_related_synonym: S(O)Me2
has_related_synonym: dimethyl sulfoxide
has_related_synonym: dimethyl sulfur oxide
has_related_synonym: dimethyl sulphoxide
has_related_synonym: dimethyli sulfoxidum
has_related_synonym: dimethylsulfoxyde
has_related_synonym: dimetil sulfoxido
has_related_synonym: dmso

glutamine
type: Class
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50331
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glutaminate
subclass of: Restriction
  on property: is conjugate base of
  some values from: glutaminium
definition: An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.
imported from: chebi.owl
charge: 0
formula: C5H10N2O3
inchi: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)
inchikey: ZDXPYRJPNDTMRX-UHFFFAOYSA-N
mass: 146.14458
monoisotopicmass: 146.06914
smiles: NC(CCC(N)=O)C(O)=O
has_alternative_id: CHEBI:24316
has_alternative_id: CHEBI:5432
database_cross_reference: Beilstein:1723795
database_cross_reference: CAS:585-21-7
database_cross_reference: CAS:6899-04-3
database_cross_reference: Gmelin:27318
database_cross_reference: KEGG:C00303
database_cross_reference: KNApSAcK:C00001359
database_cross_reference: Reaxys:1723795
database_cross_reference: Wikipedia:Glutamine
has exact synonym: Glutamine
has exact synonym: glutamine
has_obo_namespace: chebi_ontology
has_related_synonym: 2,5-diamino-5-oxopentanoic acid
has_related_synonym: 2-Aminoglutaramic acid
has_related_synonym: 2-amino-4-carbamoylbutanoic acid
has_related_synonym: Glutamin
has_related_synonym: Glutaminsaeure-5-amid
has_related_synonym: Hgln
has_related_synonym: glutamic acid gamma-amide
id: CHEBI:28300
in subset: 3 STAR

D-tyrosine
type: Class
subclass of: D-alpha-amino acid
subclass of: tyrosine
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-tyrosinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-tyrosinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-tyrosine
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_58570
definition: An optically active form of tyrosine having D-configuration.
imported from: chebi.owl
charge: 0
formula: C9H11NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m1/s1
inchikey: OUYCCCASQSFEME-MRVPVSSYSA-N
mass: 181.18858
monoisotopicmass: 181.07389
smiles: N[C@H](Cc1ccc(O)cc1)C(O)=O
has_alternative_id: CHEBI:21111
has_alternative_id: CHEBI:42299
has_alternative_id: CHEBI:4258
database_cross_reference: Beilstein:2212157
database_cross_reference: CAS:556-02-5
database_cross_reference: DrugBank:DB03839
database_cross_reference: ECMDB:ECMDB21520
database_cross_reference: Gmelin:603524
database_cross_reference: KEGG:C06420
database_cross_reference: MetaCyc:D-TYROSINE
database_cross_reference: PDBeChem:DTY
database_cross_reference: PMID:15292242
database_cross_reference: PMID:23381872
database_cross_reference: PMID:24936396
database_cross_reference: Reaxys:2212157
database_cross_reference: YMDB:YMDB00805
has exact synonym: D-TYROSINE
has exact synonym: D-Tyrosine
has exact synonym: D-tyrosine
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
has_related_synonym: (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid
has_related_synonym: (R)-3-(p-Hydroxyphenyl)alanine
has_related_synonym: D-Tyr
has_related_synonym: D-Tyrosin
has_related_synonym: DTY
id: CHEBI:28479
in subset: 3 STAR

Reserpine
type: Class
subclass of: methyl ester
subclass of: yohimban alkaloid
subclass of: CHEBI_38481
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR O15392
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P54219
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q05940
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: adrenergic uptake inhibitor
subclass of: Restriction
  on property: has role
  some values from: antihypertensive agent
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: CHEBI_65190
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76779
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78298
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_46690
has_RxCUI: 9260
definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
definition source: PMID: 15226499
definition source: https://www.drugbank.ca/drugs/DB00206
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C33H40N2O9
inchi: InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
inchikey: QEVHRUUCFGRFIF-MDEJGZGSSA-N
mass: 608.67870
monoisotopicmass: 608.27338
has_alternative_id: CHEBI:26531
has_alternative_id: CHEBI:8808
database_cross_reference: Beilstein:102014
database_cross_reference: Beilstein:5326088
database_cross_reference: CAS:50-55-5
database_cross_reference: ChemIDplus:50-55-5
database_cross_reference: DrugBank:DB00206
database_cross_reference: Drug_Central:2370
database_cross_reference: HMDB:HMDB0014351
database_cross_reference: KEGG COMPOUND:50-55-5
database_cross_reference: KEGG COMPOUND:C06539
database_cross_reference: KEGG DRUG:D00197
database_cross_reference: KEGG:C06539
database_cross_reference: KEGG:D00197
database_cross_reference: KNApSAcK:C00001763
database_cross_reference: LINCS:LSM-4162
database_cross_reference: NIST Chemistry WebBook:50-55-5
database_cross_reference: PMID:20701244
database_cross_reference: PMID:20825390
database_cross_reference: PMID:24603678
database_cross_reference: Reaxys:102014
database_cross_reference: Wikipedia:Reserpine
has exact synonym: Reserpine
has exact synonym: methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-reserpine
has_related_synonym: (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
has_related_synonym: 3,4,5-trimethoxybenzoyl methyl reserpate
has_related_synonym: Apoplon
has_related_synonym: C33H40N2O9
has_related_synonym: InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
has_related_synonym: InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N
has_related_synonym: Reserpin
has_related_synonym: Serpalan
id: CHEBI:28487
in subset: 3 STAR
label: reserpine

digitoxin
type: Class
subclass of: CHEBI_38092
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P05023
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63510
subclass of: Restriction
  on property: has functional parent
  some values from: CHEBI_42219
subclass of: Restriction
  on property: is conjugate acid of
  some values from: digitoxin(1-)
definition: A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.
definition source: PMID: 32366720; PMID: 29321306
definition source: https://www.drugbank.ca/drugs/DB01396
imported from: chebi.owl
charge: 0
formula: C41H64O13
inchi: InChI=1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
inchikey: WDJUZGPOPHTGOT-XUDUSOBPSA-N
mass: 764.93910
monoisotopicmass: 764.43469
has_alternative_id: CHEBI:23728
has_alternative_id: CHEBI:4549
database_cross_reference: Beilstein:76678
database_cross_reference: CAS:71-63-6
database_cross_reference: DrugBank:DB01396
database_cross_reference: Drug_Central:881
database_cross_reference: KEGG:C06955
database_cross_reference: KEGG:D00297
database_cross_reference: KNApSAcK:C00003617
database_cross_reference: PMID:10438974
database_cross_reference: PMID:10687899
database_cross_reference: PMID:26573786
database_cross_reference: Reaxys:76678
database_cross_reference: Wikipedia:Digitoxin
has exact synonym: 3beta-[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyloxy]-14-hydroxy-5beta-card-20(22)-enolide
has exact synonym: Digitoxin
has_obo_namespace: chebi_ontology
has_related_synonym: Crystodigin (TN)
has_related_synonym: Digitoxoside
id: CHEBI:28544
in subset: 3 STAR

valinomycin
type: Class
subclass of: cyclodepsipeptide
subclass of: CHEBI_51026
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: antiviral agent
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88227
definition: A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains.
definition source: PMID: 30858482; PMID: 16837072
imported from: chebi.owl
charge: 0
formula: C54H90N6O18
inchi: InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36+,37-,38-,39-,40+,41+,42+/m0/s1
inchikey: FCFNRCROJUBPLU-DNDCDFAISA-N
mass: 1111.32180
monoisotopicmass: 1110.63116
has_alternative_id: CHEBI:27269
has_alternative_id: CHEBI:66347
has_alternative_id: CHEBI:9924
database_cross_reference: Beilstein:78657
database_cross_reference: CAS:2001-95-8
database_cross_reference: KEGG:C06684
database_cross_reference: PMID:10603383
database_cross_reference: PMID:18633285
database_cross_reference: PMID:19347893
database_cross_reference: PMID:22683555
database_cross_reference: PMID:7590182
database_cross_reference: Reaxys:78657
database_cross_reference: Wikipedia:Valinomycin
has exact synonym: (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
has exact synonym: Valinomycin
has_obo_namespace: chebi_ontology
has_related_synonym: Cyclic(D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
has_related_synonym: cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3
id: CHEBI:28545
in subset: 3 STAR

carbamic acid
type: Class
subclass of: organonitrogen compound
subclass of: carbon oxoacid
subclass of: CHEBI_64708
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbamate
definition: A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
imported from: chebi.owl
charge: 0
formula: CH3NO2
inchi: InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)
inchikey: KXDHJXZQYSOELW-UHFFFAOYSA-N
mass: 61.04006
monoisotopicmass: 61.01638
smiles: NC(O)=O
has_alternative_id: CHEBI:22504
has_alternative_id: CHEBI:23002
has_alternative_id: CHEBI:3386
has_alternative_id: CHEBI:44573
database_cross_reference: Beilstein:1734754
database_cross_reference: CAS:463-77-4
database_cross_reference: DrugBank:DB04261
database_cross_reference: Gmelin:130345
database_cross_reference: KEGG:C01563
database_cross_reference: PDBeChem:OUT
database_cross_reference: Wikipedia:Carbamic_acid
has exact synonym: CARBAMIC ACID
has exact synonym: Carbamic acid
has exact synonym: carbamic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Aminoameisensaeure
has_related_synonym: Aminoformic acid
has_related_synonym: Carbamate
has_related_synonym: Carbamidsaeure
id: CHEBI:28616
in subset: 3 STAR

phosphorus atom
type: Class
subclass of: nonmetal atom
subclass of: pnictogen
subclass of: Restriction
  on property: has role
  some values from: macronutrient
imported from: chebi.owl
charge: 0
formula: P
inchi: InChI=1S/P
inchikey: OAICVXFJPJFONN-UHFFFAOYSA-N
mass: 30.97376
monoisotopicmass: 30.97376
smiles: [P]
has_alternative_id: CHEBI:26080
has_alternative_id: CHEBI:8168
database_cross_reference: CAS:7723-14-0
database_cross_reference: Gmelin:16235
database_cross_reference: KEGG:C06262
database_cross_reference: WebElements:P
has exact synonym: phosphorus
has_obo_namespace: chebi_ontology
has_related_synonym: 15P
has_related_synonym: P
has_related_synonym: Phosphor
has_related_synonym: Phosphorus
has_related_synonym: fosforo
has_related_synonym: phosphore
has_related_synonym: phosphorus
id: CHEBI:28659
in subset: 3 STAR

flavonols
type: Class
subclass of: hydroxyflavone
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_58588
definition: Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group.
imported from: chebi.owl
charge: 0
formula: C15HO3R9
mass: 229.16660
monoisotopicmass: 228.99257
smiles: Oc1c(oc2c([*])c([*])c([*])c([*])c2c1=O)-c1c([*])c([*])c([*])c([*])c1[*]
has_alternative_id: CHEBI:13639
has_alternative_id: CHEBI:24052
has_alternative_id: CHEBI:71969
database_cross_reference: MetaCyc:Flavonols
database_cross_reference: Wikipedia:Flavonol
has_obo_namespace: chebi_ontology
has_related_synonym: 3-hydroxyflavones
has_related_synonym: a flavonol
id: CHEBI:28802
in subset: 3 STAR

flavanones
type: Class
subclass of: CHEBI_38672
subclass of: CHEBI 3992
definition: Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives.
imported from: chebi.owl
charge: 0
formula: C15H2O2R10
mass: 214.176
monoisotopicmass: 214.00548
has_alternative_id: CHEBI:13636
has_alternative_id: CHEBI:24038
has_alternative_id: CHEBI:24054
database_cross_reference: MetaCyc:FLAVANONES
database_cross_reference: Wikipedia:Flavanone
has_obo_namespace: chebi_ontology
has_related_synonym: 2,3-dihydroflavones
has_related_synonym: a flavanone
id: CHEBI:28863
in subset: 3 STAR

fatty acid anion
type: Class
subclass of: lipid
subclass of: CHEBI_35757
subclass of: Restriction
  on property: is conjugate base of
  some values from: fatty acid
definition: The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.
imported from: chebi.owl
charge: -1
formula: CO2R
mass: 44.00950
monoisotopicmass: 43.98983
smiles: [O-]C([*])=O
has_alternative_id: CHEBI:13634
has_alternative_id: CHEBI:24022
has_alternative_id: CHEBI:4985
database_cross_reference: KEGG:C02403
database_cross_reference: PMID:18628202
has exact synonym: Fatty acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: Alkanate
has_related_synonym: Fettsaeureanion
has_related_synonym: Fettsaeureanionen
has_related_synonym: a fatty acid
has_related_synonym: acido graso anionico
has_related_synonym: acidos grasos anionicos
has_related_synonym: anion de l'acide gras
has_related_synonym: fatty acid anions
id: CHEBI:28868
in subset: 3 STAR

nigeran
type: Class
subclass of: nigerans
imported from: chebi.owl
has_alternative_id: CHEBI:24254
has_alternative_id: CHEBI:7568
has_obo_namespace: chebi_ontology
id: CHEBI:28899
in subset: 1 STAR

ammonium
type: Class
subclass of: nitrogen hydride
subclass of: CHEBI_50313
subclass of: CHEBI_60242
subclass of: Restriction
  on property: has role
  some values from: cofactor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: ammonia
definition: An onium cation obtained by protonation of ammonia.
imported from: chebi.owl
charge: +1
formula: H4N
inchi: InChI=1S/H3N/h1H3/p+1
inchikey: QGZKDVFQNNGYKY-UHFFFAOYSA-O
mass: 18.03850
monoisotopicmass: 18.03383
smiles: [H][N+]([H])([H])[H]
has_alternative_id: CHEBI:22534
has_alternative_id: CHEBI:49783
has_alternative_id: CHEBI:7435
database_cross_reference: CAS:14798-03-9
database_cross_reference: Gmelin:84
database_cross_reference: KEGG:C01342
database_cross_reference: MetaCyc:AMMONIUM
database_cross_reference: MolBase:929
database_cross_reference: PDBeChem:NH4
database_cross_reference: PMID:11319011
database_cross_reference: PMID:11341317
database_cross_reference: PMID:12096804
database_cross_reference: PMID:14512268
database_cross_reference: PMID:14879753
database_cross_reference: PMID:16345391
database_cross_reference: PMID:16903292
database_cross_reference: PMID:17392693
database_cross_reference: PMID:18515490
database_cross_reference: PMID:19199063
database_cross_reference: PMID:19596600
database_cross_reference: PMID:19682559
database_cross_reference: PMID:19716251
database_cross_reference: PMID:21993530
database_cross_reference: PMID:22265469
database_cross_reference: PMID:22524020
database_cross_reference: PMID:22562341
database_cross_reference: PMID:22631217
database_cross_reference: Reaxys:16093784
database_cross_reference: Wikipedia:Ammonium
has exact synonym: ammonium
has exact synonym: azanium
has_obo_namespace: chebi_ontology
has_related_synonym: Ammonium(1+)
has_related_synonym: NH4(+)
has_related_synonym: NH4+
has_related_synonym: [NH4](+)
has_related_synonym: ammonium cation
has_related_synonym: ammonium ion
id: CHEBI:28938
in subset: 3 STAR

astemizole
type: Class
subclass of: benzimidazoles
subclass of: piperidines
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR O95259
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P10636
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q12809
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P35367
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_37955
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50857
definition: A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
definition source: PMID: 24841273
definition source: https://www.drugbank.ca/drugs/DB00637
imported from: chebi.owl
charge: 0
formula: C28H31FN4O
inchi: InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)
inchikey: GXDALQBWZGODGZ-UHFFFAOYSA-N
mass: 458.57030
monoisotopicmass: 458.24819
database_cross_reference: Beilstein:4830190
database_cross_reference: CAS:68844-77-9
database_cross_reference: DrugBank:DB00637
database_cross_reference: Drug_Central:249
database_cross_reference: KEGG:C06832
database_cross_reference: KEGG:D00234
database_cross_reference: LINCS:LSM-5502
database_cross_reference: Patent:EP5318
database_cross_reference: Patent:US4219559
has exact synonym: 1-(4-fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine
has_obo_namespace: chebi_ontology
has_related_synonym: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole
has_related_synonym: 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole
has_related_synonym: Astemison
has_related_synonym: astemizol
has_related_synonym: astemizole
has_related_synonym: astemizolum
id: CHEBI:2896
in subset: 3 STAR

dicarboxylic acid dianion
type: Class
subclass of: dicarboxylic acid anion
subclass of: CHEBI_38716
definition: A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.
imported from: chebi.owl
charge: -2
formula: C2O4R
mass: 88.019
monoisotopicmass: 87.97966
smiles: [O-]C(=O)[*]C([O-])=O
has_alternative_id: CHEBI:13632
has_alternative_id: CHEBI:23688
has_alternative_id: CHEBI:23689
has_alternative_id: CHEBI:38711
has exact synonym: dicarboxylic acid dianion
has_obo_namespace: chebi_ontology
has_related_synonym: a dicarboxylate
has_related_synonym: dicarboxylate
has_related_synonym: dicarboxylates
has_related_synonym: dicarboxylic acid dianions
id: CHEBI:28965
in subset: 3 STAR

carbonic acid
type: Class
subclass of: carbon oxoacid
subclass of: CHEBI_36961
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogencarbonate
imported from: chebi.owl
charge: 0
formula: CH2O3
inchi: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)
inchikey: BVKZGUZCCUSVTD-UHFFFAOYSA-N
mass: 62.02478
monoisotopicmass: 62.00039
smiles: OC(O)=O
has_alternative_id: CHEBI:13351
has_alternative_id: CHEBI:23017
has_alternative_id: CHEBI:23744
has_alternative_id: CHEBI:3401
database_cross_reference: CAS:463-79-6
database_cross_reference: Gmelin:25554
database_cross_reference: KEGG:C01353
database_cross_reference: PDBeChem:CO3
has exact synonym: Carbonic acid
has exact synonym: carbonic acid
has exact synonym: dihydroxidooxidocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: Dihydrogen carbonate
has_related_synonym: H2CO3
has_related_synonym: Koehlensaeure
has_related_synonym: [CO(OH)2]
id: CHEBI:28976
in subset: 3 STAR

arginine
type: Class
subclass of: guanidines
subclass of: polar amino acid
subclass of: alpha-amino acid
subclass of: Restriction
  on property: has part
  some values from: CHEBI_50340
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: argininate
subclass of: Restriction
  on property: is conjugate base of
  some values from: argininium(1+)
definition: An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.
imported from: chebi.owl
charge: 0
formula: C6H14N4O2
inchi: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)
inchikey: ODKSFYDXXFIFQN-UHFFFAOYSA-N
mass: 174.20112
monoisotopicmass: 174.11168
smiles: NC(CCCNC(N)=N)C(O)=O
has_alternative_id: CHEBI:22616
has_alternative_id: CHEBI:2643
database_cross_reference: Beilstein:1725411
database_cross_reference: CAS:7200-25-1
database_cross_reference: KEGG:C02385
database_cross_reference: PMID:10848923
database_cross_reference: Reaxys:1725411
database_cross_reference: Wikipedia:L-Arginine
has exact synonym: Arginine
has exact synonym: arginine
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Amino-5-guanidinovaleric acid
has_related_synonym: 2-amino-5-(carbamimidamido)pentanoic acid
has_related_synonym: 2-amino-5-guanidinopentanoic acid
has_related_synonym: Arginin
has_related_synonym: Harg
id: CHEBI:29016
in subset: 3 STAR

carboxylic acid anion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carboxylic acid
definition: The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
imported from: chebi.owl
charge: -1
formula: CO2R
mass: 44.00950
monoisotopicmass: 43.98983
smiles: [O-]C([*])=O
has_alternative_id: CHEBI:13626
has_alternative_id: CHEBI:13945
has_alternative_id: CHEBI:23026
has_alternative_id: CHEBI:58657
has_obo_namespace: chebi_ontology
has_related_synonym: a carboxylate
has_related_synonym: carboxylic acid anions
has_related_synonym: carboxylic anions
id: CHEBI:29067
in subset: 3 STAR

dextrorphan
type: Class
subclass of: morphinane alkaloid
imported from: chebi.owl
charge: 0
formula: C17H23NO
inchi: InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1
inchikey: JAQUASYNZVUNQP-PVAVHDDUSA-N
mass: 257.37066
monoisotopicmass: 257.17796
database_cross_reference: Beilstein:88093
database_cross_reference: CAS:125-73-5
database_cross_reference: LINCS:LSM-36603
has exact synonym: 17-methyl-9alpha,13alpha,14alpha-morphinan-3-ol
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-3-hydroxy-N-methylmorphinan
has_related_synonym: d-3-hydroxy-N-methylmorphinan
has_related_synonym: dextrorphan
has_related_synonym: dextrorphane
has_related_synonym: dextrorphanum
id: CHEBI:29133
in subset: 3 STAR

desloratadine
type: Class
subclass of: CHEBI_48593
subclass of: Restriction
  on property: has role
  some values from: CHEBI_37955
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48873
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49103
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50857
definition: Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness.
imported from: chebi.owl
charge: 0
formula: C19H19ClN2
inchi: InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
inchikey: JAUOIFJMECXRGI-UHFFFAOYSA-N
mass: 310.82100
monoisotopicmass: 310.12368
smiles: Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1
database_cross_reference: Beilstein:4263164
database_cross_reference: CAS:100643-71-8
database_cross_reference: DrugBank:DB00967
database_cross_reference: Drug_Central:814
database_cross_reference: KEGG:D03693
database_cross_reference: LINCS:LSM-5887
database_cross_reference: PMID:11844681
database_cross_reference: PMID:15482930
database_cross_reference: PMID:9934454
database_cross_reference: Patent:EP208855
database_cross_reference: Patent:US4659716
database_cross_reference: Wikipedia:Desloratadine
has exact synonym: 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
has exact synonym: DESLORATADINE
has_obo_namespace: chebi_ontology
has_related_synonym: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
has_related_synonym: 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
has_related_synonym: descarboethoxyloratadine
has_related_synonym: desloratadine
id: CHEBI:291342
in subset: 3 STAR

sulfonic acid
type: Class
subclass of: sulfur oxoacid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfonate
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_48854
imported from: chebi.owl
charge: 0
formula: H2O3S
inchi: InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)
inchikey: BDHFUVZGWQCTTF-UHFFFAOYSA-N
mass: 82.08008
monoisotopicmass: 81.97247
smiles: [H]S(O)(=O)=O
database_cross_reference: Gmelin:1404640
has exact synonym: hydridohydroxidodioxidosulfur
has exact synonym: sulfonic acid
has_obo_namespace: chebi_ontology
has_related_synonym: HSHO3
has_related_synonym: Sulfonsaeure
has_related_synonym: [SHO2(OH)]
has_related_synonym: acide sulfonique
has_related_synonym: sulphonic acid
id: CHEBI:29214
in subset: 3 STAR

thiol
type: Class
subclass of: organosulfur compound
subclass of: Restriction
  on property: has part
  some values from: thiol group
definition: An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
imported from: chebi.owl
charge: 0
formula: HSR
mass: 33.07300
monoisotopicmass: 32.97990
smiles: S[*]
has_alternative_id: CHEBI:13443
has_alternative_id: CHEBI:13696
has_alternative_id: CHEBI:17366
has_alternative_id: CHEBI:26969
has_alternative_id: CHEBI:8766
has_alternative_id: CHEBI:9556
database_cross_reference: KEGG:C00145
database_cross_reference: Wikipedia:Thiol
has exact synonym: Thiol
has exact synonym: thiols
has_obo_namespace: chebi_ontology
has_related_synonym: Mercaptan
has_related_synonym: Merkaptan
has_related_synonym: RSH
has_related_synonym: a thiol
has_related_synonym: mercaptans
has_related_synonym: thiols
id: CHEBI:29256
in subset: 3 STAR

dinitride(2-)
type: Class
subclass of: diatomic nitrogen
subclass of: Restriction
  on property: is conjugate base of
  some values from: diazenide
imported from: chebi.owl
charge: -2
formula: N2
inchi: InChI=1S/N2/c1-2/q-2
inchikey: BZZJUZUZJRQHLZ-UHFFFAOYSA-N
mass: 28.01348
monoisotopicmass: 28.00725
smiles: [N-]=[N-]
database_cross_reference: Gmelin:1565041
has exact synonym: diazenediide
has exact synonym: dinitride(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: N2(2-)
id: CHEBI:29277
in subset: 3 STAR

azanide
type: Class
subclass of: nitrogen hydride
subclass of: CHEBI_79389
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydridonitrate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: ammonia
imported from: chebi.owl
charge: -1
formula: H2N
inchi: InChI=1S/H2N/h1H2/q-1
inchikey: HYGWNUKOUCZBND-UHFFFAOYSA-N
mass: 16.02262
monoisotopicmass: 16.01927
smiles: [H][N-][H]
has exact synonym: amide
has exact synonym: azanide
has exact synonym: dihydridonitrate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: NH2(-)
id: CHEBI:29337
in subset: 3 STAR

hydridonitrate(2-)
type: Class
subclass of: nitrogen hydride
subclass of: CHEBI_79388
subclass of: Restriction
  on property: is conjugate base of
  some values from: azanide
definition: A divalent inorganic anion resulting from the removal of two protons from ammonia.
imported from: chebi.owl
charge: -2
formula: HN
inchi: InChI=1S/HN/h1H/q-2
inchikey: DZQYTNGKSBCIOE-UHFFFAOYSA-N
mass: 15.01468
monoisotopicmass: 15.01200
smiles: [N--][H]
has exact synonym: azanediide
has exact synonym: hydridonitrate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: NH(2-)
has_related_synonym: imide
id: CHEBI:29340
in subset: 3 STAR

monocarboxylic acid amide
type: Class
subclass of: CHEBI_37622
definition: A carboxamide derived from a monocarboxylic acid.
imported from: chebi.owl
charge: 0
formula: CNOR3
mass: 42.01680
monoisotopicmass: 41.99799
smiles: [*]N([*])C([*])=O
has_alternative_id: CHEBI:13211
has_alternative_id: CHEBI:22207
has_alternative_id: CHEBI:25383
has_alternative_id: CHEBI:6977
has_obo_namespace: chebi_ontology
has_related_synonym: monocarboxylic acid amides
id: CHEBI:29347
in subset: 3 STAR

fatty amide
type: Class
subclass of: monocarboxylic acid amide
subclass of: CHEBI_61697
subclass of: Restriction
  on property: has functional parent
  some values from: fatty acid
definition: A monocarboxylic acid amide derived from a fatty acid.
imported from: chebi.owl
charge: 0
formula: CHNOR2
mass: 43.025
monoisotopicmass: 43.00581
has_alternative_id: CHEBI:13247
has_alternative_id: CHEBI:22310
has_alternative_id: CHEBI:22330
has_alternative_id: CHEBI:2572
has_alternative_id: CHEBI:35749
has_alternative_id: CHEBI:38838
database_cross_reference: KEGG:C02244
database_cross_reference: LIPID_MAPS_class:LMFA08
has exact synonym: fatty amide
has_obo_namespace: chebi_ontology
has_related_synonym: Aliphatic amide
has_related_synonym: fatty amides
id: CHEBI:29348
in subset: 3 STAR

methanediide
type: Class
subclass of: CHEBI_38222
subclass of: Restriction
  on property: is conjugate base of
  some values from: methanide
imported from: chebi.owl
charge: -2
formula: CH2
inchi: InChI=1S/CH2/h1H2/q-2
inchikey: PZPOWPOFQLSNJO-UHFFFAOYSA-N
mass: 14.02658
monoisotopicmass: 14.01675
smiles: [H][C--][H]
database_cross_reference: Beilstein:5915711
database_cross_reference: Gmelin:322698
has exact synonym: dihydridocarbonate(2-)
has exact synonym: methanediide
has_obo_namespace: chebi_ontology
has_related_synonym: CH2(2-)
has_related_synonym: [CH2](2-)
id: CHEBI:29360
in subset: 3 STAR

oxonium
type: Class
subclass of: oxygen hydride
subclass of: CHEBI_50313
subclass of: Restriction
  on property: is conjugate acid of
  some values from: water
imported from: chebi.owl
charge: +1
formula: H3O
inchi: InChI=1S/H2O/h1H2/p+1
inchikey: XLYOFNOQVPJJNP-UHFFFAOYSA-O
mass: 19.02322
monoisotopicmass: 19.01784
smiles: [H][O+]([H])[H]
database_cross_reference: CAS:13968-08-6
database_cross_reference: Gmelin:141
database_cross_reference: MolBase:1646
has exact synonym: aquahydrogen(1+)
has exact synonym: oxidanium
has exact synonym: oxonium
has exact synonym: trihydridooxygen(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: H3O(+)
has_related_synonym: Hydronium cation
has_related_synonym: Hydronium ion
has_related_synonym: [OH3](+)
id: CHEBI:29412
in subset: 3 STAR

methanide
type: Class
subclass of: CHEBI_38222
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methanediide
subclass of: Restriction
  on property: is conjugate base of
  some values from: methane
imported from: chebi.owl
charge: -1
formula: CH3
inchi: InChI=1S/CH3/h1H3/q-1
inchikey: LGRLWUINFJPLSH-UHFFFAOYSA-N
mass: 15.03452
monoisotopicmass: 15.02402
smiles: [H][C-]([H])[H]
database_cross_reference: Beilstein:1813938
database_cross_reference: CAS:15194-58-8
database_cross_reference: Gmelin:259263
has exact synonym: methanide
has exact synonym: trihydridocarbonate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: CH3(-)
has_related_synonym: [CH3](-)
has_related_synonym: lambda(2)-methanuide
has_related_synonym: methyl anion
id: CHEBI:29438
in subset: 3 STAR

avermectin B1a
type: Class
subclass of: CHEBI_50344
imported from: chebi.owl
charge: 0
formula: C48H72O14
inchi: InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
inchikey: RRZXIRBKKLTSOM-XPNPUAGNSA-N
mass: 873.07690
monoisotopicmass: 872.49221
database_cross_reference: BPDB:8
database_cross_reference: Beilstein:3645625
database_cross_reference: CAS:65195-55-3
database_cross_reference: KEGG:C11983
database_cross_reference: LIPID_MAPS_instance:LMPK04000024
database_cross_reference: MetaCyc:CPD-12963
database_cross_reference: VSDB:8
has exact synonym: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
has exact synonym: Avermectin B1a
has_obo_namespace: chebi_ontology
has_related_synonym: abamectin component B1a
id: CHEBI:29534
in subset: 3 STAR

avermectin B1b
type: Class
subclass of: CHEBI_50344
imported from: chebi.owl
charge: 0
formula: C47H70O14
inchi: InChI=1S/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1
inchikey: ZFUKERYTFURFGA-PVVXTEPVSA-N
mass: 859.05030
monoisotopicmass: 858.47656
database_cross_reference: Beilstein:8399072
database_cross_reference: CAS:65195-56-4
database_cross_reference: KEGG:C11967
database_cross_reference: LIPID_MAPS_instance:LMPK04000020
database_cross_reference: MetaCyc:CPD-12964
has exact synonym: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
has exact synonym: Avermectin B1b
has_obo_namespace: chebi_ontology
has_related_synonym: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
has_related_synonym: abamectin component B1b
id: CHEBI:29537
in subset: 3 STAR

Azithromycin
type: Class
subclass of: macrolide antibiotic
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q9UM07
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_2697049
subclass of: Restriction
  on property: has role
  some values from: xenobiotic
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36047
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78298
subclass of: Restriction
  on property: has role
  some values from: mitochondrial ribosomes
has_RxCUI: 18631
definition: A macrolide antibiotic that has formula C38H72N2O12.
definition: A macrolide antibiotic useful for the treatment of bacterial infections.
definition source: PMID: 32533455
definition source: Reference: PMID: 24794904
definition source: https://www.drugbank.ca/drugs/DB00207
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C38H72N2O12
inchi: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
inchikey: MQTOSJVFKKJCRP-BICOPXKESA-N
mass: 748.98450
monoisotopicmass: 748.50853
has_alternative_id: CHEBI:46596
database_cross_reference: Beilstein:5387583
database_cross_reference: CAS:83905-01-5
database_cross_reference: ChemIDplus:83905-01-5
database_cross_reference: DrugBank:DB00207
database_cross_reference: Drug_Central:276
database_cross_reference: HMDB:HMDB0014352
database_cross_reference: KEGG COMPOUND:C06838
database_cross_reference: KEGG DRUG:D07486
database_cross_reference: KEGG:C06838
database_cross_reference: KEGG:D07486
database_cross_reference: LINCS:LSM-5821
database_cross_reference: PDBeChem:ZIT
database_cross_reference: PMID:15143799
database_cross_reference: PMID:18253999
database_cross_reference: Patent:BE892357
database_cross_reference: Patent:US4517359
database_cross_reference: Reaxys:5387583
database_cross_reference: Reaxys:8820027
database_cross_reference: Wikipedia:Azithromycin
has exact synonym: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
has_obo_namespace: chebi_ontology
has_related_synonym: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
has_related_synonym: Azenil
has_related_synonym: Azifast
has_related_synonym: Azigram
has_related_synonym: Azimakrol
has_related_synonym: Azitromin
has_related_synonym: C38H72N2O12
has_related_synonym: Hemomycin
has_related_synonym: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
has_related_synonym: InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N
has_related_synonym: Zithromax
has_related_synonym: Zmax
has_related_synonym: azithromycine
has_related_synonym: azithromycinum
has_related_synonym: azitromicina
id: CHEBI:2955
in subset: 3 STAR
label: azithromycin

teicoplanin
type: Class
subclass of: CHEBI_60004
subclass of: Restriction
  on property: has part
  some values from: teicoplanin A2-1
subclass of: Restriction
  on property: has part
  some values from: teicoplanin A2-3
subclass of: Restriction
  on property: has part
  some values from: teicoplanin A2-4
subclass of: Restriction
  on property: has part
  some values from: teicoplanin A2-5
subclass of: Restriction
  on property: has part
  some values from: teicoplanin A3-1
subclass of: Restriction
  on property: has part
  some values from: CHEBI_85251
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36047
definition: A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.
definition source: PMID: 26953343; PMID: 28855003
imported from: chebi.owl
charge: 0
database_cross_reference: CAS:61036-62-2
database_cross_reference: DrugBank:DB06149
database_cross_reference: KEGG:C15820
database_cross_reference: KEGG:D02142
database_cross_reference: PMID:1416858
database_cross_reference: PMID:24506456
database_cross_reference: PMID:24693468
database_cross_reference: PMID:25190719
database_cross_reference: PMID:25218156
database_cross_reference: PMID:25224001
database_cross_reference: PMID:25358800
database_cross_reference: PMID:25616054
database_cross_reference: PMID:25726436
database_cross_reference: Reaxys:8196734
database_cross_reference: Wikipedia:Teicoplanin
has_obo_namespace: chebi_ontology
has_related_synonym: Targocid
has_related_synonym: antibiotic 8327A
has_related_synonym: teicoplanin
has_related_synonym: teicoplanina
has_related_synonym: teicoplanine
has_related_synonym: teicoplaninum
id: CHEBI:29687
in subset: 3 STAR

nitro group
type: Class
subclass of: inorganic group
subclass of: CHEBI_51144
imported from: chebi.owl
charge: 0
formula: NO2
mass: 46.00550
monoisotopicmass: 45.99290
smiles: *[N+](=O)[O-]
has exact synonym: nitro
has_obo_namespace: chebi_ontology
has_related_synonym: -NO2
id: CHEBI:29785
in subset: 3 STAR

baicalein
type: Class
subclass of: trihydroxyflavone
subclass of: Restriction
  on property: has role
  some values from: EC 4.1.1.17 (ornithine decarboxylase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: ferroptosis inhibitor
subclass of: Restriction
  on property: has role
  some values from: geroprotector
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35718
definition: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
imported from: chebi.owl
charge: 0
formula: C15H10O5
inchi: InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
inchikey: FXNFHKRTJBSTCS-UHFFFAOYSA-N
mass: 270.240
monoisotopicmass: 270.05282
database_cross_reference: Beilstein:272683
database_cross_reference: CAS:491-67-8
database_cross_reference: Chemspider:4444924
database_cross_reference: DrugBank:DB16101
database_cross_reference: FooDB:FDB012057
database_cross_reference: HMDB:HMDB0134890
database_cross_reference: KEGG:C10023
database_cross_reference: KNApSAcK:C00001022
database_cross_reference: LINCS:LSM-6355
database_cross_reference: LIPID_MAPS_instance:LMPK12111095
database_cross_reference: MetaCyc:CPD-12724
database_cross_reference: PDBeChem:3WL
database_cross_reference: PMID:10724177
database_cross_reference: PMID:11513834
database_cross_reference: PMID:15853750
database_cross_reference: PMID:22114686
database_cross_reference: PMID:22891631
database_cross_reference: PMID:23098745
database_cross_reference: PMID:23339711
database_cross_reference: PMID:26268338
database_cross_reference: PMID:28166217
database_cross_reference: PMID:31976018
database_cross_reference: PMID:32618193
database_cross_reference: PMID:32737471
database_cross_reference: PMID:32781058
database_cross_reference: PMID:33062636
database_cross_reference: PMID:33075645
database_cross_reference: PMID:33095440
database_cross_reference: PMID:33121927
database_cross_reference: PMID:33166766
database_cross_reference: PMID:33272570
database_cross_reference: PMID:33348871
database_cross_reference: PMID:33446085
database_cross_reference: PMID:33491508
database_cross_reference: PMID:33511213
database_cross_reference: PMID:33670013
database_cross_reference: PMID:33777154
database_cross_reference: PMID:33779329
database_cross_reference: PMID:33794322
database_cross_reference: PMID:33880917
database_cross_reference: PMID:33921971
database_cross_reference: PMID:33939310
database_cross_reference: PMID:33996574
database_cross_reference: PMID:34008261
database_cross_reference: PMID:34015760
database_cross_reference: PMID:34038512
database_cross_reference: PMID:34044073
database_cross_reference: PMID:34060266
database_cross_reference: PMID:34072443
database_cross_reference: PMID:59001
database_cross_reference: Patent:CN102429899
database_cross_reference: Reaxys:272683
database_cross_reference: Wikipedia:Baicalein
has exact synonym: 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
has exact synonym: Baicalein
has_obo_namespace: chebi_ontology
has_related_synonym: 5,6,7-Trihydroxyflavone
has_related_synonym: 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one
has_related_synonym: Noroxylin
id: CHEBI:2979
in subset: 3 STAR

glycyrrhizinate(3-)
type: Class
subclass of: tricarboxylic acid trianion
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P01375
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P28845
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P42574
subclass of: Restriction
  on property: chemical induces protein
  some values from: PR P06858
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: chemical modulates response in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: is conjugate base of
  some values from: glycyrrhizinic acid
definition: A tricarboxylic acid trianion that is the conjugate base of glycyrrhizinic acid.
definition source: PMID: 21762538; PMID: 16837072
definition source: PMID: 21762538; PMID: 16837072; PMID: 12814717
definition source: https://www.drugbank.ca/drugs/DB13751
imported from: chebi.owl
charge: -3
formula: C42H59O16
inchi: InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/p-3/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
inchikey: LPLVUJXQOOQHMX-QWBHMCJMSA-K
mass: 819.90826
monoisotopicmass: 819.38196
has_alternative_id: CHEBI:14367
has_alternative_id: CHEBI:24419
database_cross_reference: KEGG:C02284
database_cross_reference: KEGG:D00157
database_cross_reference: KNApSAcK:C00003522
database_cross_reference: MetaCyc:GLYCYRRHIZINATE
has_obo_namespace: chebi_ontology
has_related_synonym: (3beta,20beta)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucuronosyl-beta-D-glucosiduronic acid
has_related_synonym: Glycyrrhizic acid
has_related_synonym: Glycyrrhizin
has_related_synonym: Glycyrrhizinate
has_related_synonym: glycyrrhizin
id: CHEBI:29807
in subset: 3 STAR

baicalin
type: Class
subclass of: glucosiduronic acid
subclass of: CHEBI_38686
subclass of: CHEBI_50018
subclass of: CHEBI_63367
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: antiatherosclerotic agent
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: ferroptosis inhibitor
subclass of: Restriction
  on property: has role
  some values from: antioxidant
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: non-steroidal anti-inflammatory drug
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50266
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63726
definition: The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.
definition source: PMID: 15288617
imported from: chebi.owl
charge: 0
formula: C21H18O11
inchi: InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
inchikey: IKIIZLYTISPENI-ZFORQUDYSA-N
mass: 446.364
monoisotopicmass: 446.08491
database_cross_reference: Beilstein:70480
database_cross_reference: CAS:21967-41-9
database_cross_reference: Drug_Central:4055
database_cross_reference: HMDB:HMDB0041832
database_cross_reference: KEGG:C10025
database_cross_reference: KNApSAcK:C00001024
database_cross_reference: LIPID_MAPS_instance:LMPK12111081
database_cross_reference: MetaCyc:CPD-12725
database_cross_reference: PDBeChem:0XE
database_cross_reference: PMCID:PMC8165801
database_cross_reference: PMID:10724177
database_cross_reference: PMID:18650094
database_cross_reference: PMID:21087019
database_cross_reference: PMID:22467027
database_cross_reference: PMID:23142347
database_cross_reference: PMID:23302221
database_cross_reference: PMID:23354080
database_cross_reference: PMID:23523628
database_cross_reference: PMID:25847243
database_cross_reference: PMID:32707128
database_cross_reference: PMID:32795339
database_cross_reference: PMID:33008383
database_cross_reference: PMID:33224035
database_cross_reference: PMID:33269624
database_cross_reference: PMID:33352232
database_cross_reference: PMID:33493657
database_cross_reference: PMID:33595821
database_cross_reference: PMID:33652818
database_cross_reference: PMID:33732310
database_cross_reference: PMID:33781030
database_cross_reference: PMID:33801847
database_cross_reference: PMID:33815110
database_cross_reference: PMID:33891262
database_cross_reference: PMID:33921971
database_cross_reference: PMID:33923637
database_cross_reference: PMID:33935719
database_cross_reference: PMID:33955315
database_cross_reference: PMID:33992597
database_cross_reference: PMID:34029124
database_cross_reference: PMID:34044073
database_cross_reference: PMID:34053448
database_cross_reference: Patent:CN102584918
database_cross_reference: Patent:WO2012119458
database_cross_reference: Reaxys:70480
database_cross_reference: Wikipedia:Baicalin
has exact synonym: 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid
has exact synonym: Baicalin
has_obo_namespace: chebi_ontology
has_related_synonym: 5,6,7-trihydroxyflavone 7-O-beta-D-glucuronide
has_related_synonym: 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid
has_related_synonym: 7-D-glucuronic acid-5,6-dihydroxyflavone
has_related_synonym: baicalein 7-O-glucuronide
has_related_synonym: baicalein 7-glucuronide
id: CHEBI:2981
in subset: 3 STAR

thiol group
type: Class
subclass of: inorganic group
subclass of: Restriction
  on property: is substituent group from
  some values from: hydrogen sulfide
imported from: chebi.owl
charge: 0
formula: HS
mass: 33.074
monoisotopicmass: 32.97990
smiles: *S[H]
has_alternative_id: CHEBI:26821
has_alternative_id: CHEBI:29916
has exact synonym: sulfanyl
has exact synonym: thiol
has exact synonym: thiol group
has_obo_namespace: chebi_ontology
has_related_synonym: -SH
has_related_synonym: HS-
has_related_synonym: Mercaptogruppe
has_related_synonym: Merkaptogruppe
has_related_synonym: Sulfhydrylgruppe
has_related_synonym: Thiolgruppe
has_related_synonym: mercapto group
has_related_synonym: sulfhydryl group
has_related_synonym: sulphydryl group
id: CHEBI:29917
in subset: 3 STAR

hydrosulfide
type: Class
subclass of: sulfur hydride
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: sulfide(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: hydrogen sulfide
imported from: chebi.owl
charge: -1
formula: HS
inchi: InChI=1S/H2S/h1H2/p-1
inchikey: RWSOTUBLDIXVET-UHFFFAOYSA-M
mass: 33.07394
monoisotopicmass: 32.98044
smiles: [S-][H]
database_cross_reference: CAS:15035-72-0
database_cross_reference: Gmelin:24766
has exact synonym: hydrogen(sulfide)(1-)
has exact synonym: hydrosulfide
has exact synonym: sulfanide
has_obo_namespace: chebi_ontology
has_related_synonym: HS anion
has_related_synonym: HS(-)
has_related_synonym: hydrogen sulfide
id: CHEBI:29919
in subset: 3 STAR

sulfo group
type: Class
subclass of: inorganic group
subclass of: Restriction
  on property: is substituent group from
  some values from: sulfonic acid
imported from: chebi.owl
charge: 0
formula: HO3S
mass: 81.07214
monoisotopicmass: 80.96464
smiles: S(=O)(O)(*)=O
database_cross_reference: PDBeChem:SFO
has exact synonym: SULFO GROUP
has exact synonym: hydroxydioxo-lambda(6)-sulfanyl
has exact synonym: hydroxysulfonyl
has exact synonym: sulfo
has_obo_namespace: chebi_ontology
has_related_synonym: -S(O)2(OH)
id: CHEBI:29922
in subset: 3 STAR

L-lysine residue
type: Class
subclass of: lysine residue
subclass of: proteinogenic amino-acid residue
subclass of: CHEBI_83228
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-lysinium residue
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysine residue
subclass of: Restriction
  on property: is substituent group from
  some values from: L-lysine
imported from: chebi.owl
charge: 0
formula: C6H12N2O
mass: 128.17236
monoisotopicmass: 128.09496
smiles: C([C@@H](C(*)=O)N*)CCCN
database_cross_reference: RESID:AA0012
has exact synonym: L-lysine residue
has_obo_namespace: chebi_ontology
has_related_synonym: -Lys-
has_related_synonym: K
has_related_synonym: L-lysine
has_related_synonym: L-lysine base residue
has_related_synonym: L-lysyl
has_related_synonym: Lys
id: CHEBI:29967
in subset: 3 STAR

D-lysine residue
type: Class
subclass of: lysine residue
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-lysinium residue
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysine residue
subclass of: Restriction
  on property: is substituent group from
  some values from: D-lysine
imported from: chebi.owl
charge: 0
formula: C6H12N2O
mass: 128.17236
monoisotopicmass: 128.09496
smiles: C([C@H](C(*)=O)N*)CCCN
has exact synonym: D-lysine residue
has_obo_namespace: chebi_ontology
has_related_synonym: -D-Lys-
has_related_synonym: D-Lys
has_related_synonym: D-lysine base residue
has_related_synonym: DLys
id: CHEBI:29968
in subset: 3 STAR

L-lysinium residue
type: Class
subclass of: lysinium residue
subclass of: proteinogenic amino-acid residue cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-lysine residue
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysinium residue
subclass of: Restriction
  on property: is substituent group from
  some values from: L-lysinium(1+)
imported from: chebi.owl
charge: +1
formula: C6H13N2O
mass: 129.180
monoisotopicmass: 129.10279
smiles: C([C@@H](C(*)=O)N*)CCC[NH3+]
has exact synonym: L-lysinium residue
has_obo_namespace: chebi_ontology
has_related_synonym: L-lysine residue
has_related_synonym: LysH(+)
id: CHEBI:29969
in subset: 3 STAR

D-lysinium residue
type: Class
subclass of: lysinium residue
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-lysine residue
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysinium residue
subclass of: Restriction
  on property: is substituent group from
  some values from: D-lysinium(1+)
imported from: chebi.owl
charge: +1
formula: C6H13N2O
mass: 129.18030
monoisotopicmass: 129.10279
smiles: C([C@H](C(*)=O)N*)CCC[NH3+]
has exact synonym: D-lysinium residue
has_obo_namespace: chebi_ontology
has_related_synonym: D-LysH(+)
id: CHEBI:29970
in subset: 3 STAR

L-glutamate(1-)
type: Class
subclass of: glutamate(1-)
subclass of: CHEBI_62031
subclass of: Restriction
  on property: has role
  some values from: EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-glutamate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-glutamic acid
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-glutamate(1-)
definition: An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group
imported from: chebi.owl
charge: -1
formula: C5H8NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1
inchikey: WHUUTDBJXJRKMK-VKHMYHEASA-M
mass: 146.12136
monoisotopicmass: 146.04588
smiles: [NH3+][C@@H](CCC([O-])=O)C([O-])=O
has_alternative_id: CHEBI:13107
has_alternative_id: CHEBI:21301
database_cross_reference: CAS:11070-68-1
database_cross_reference: Gmelin:936654
database_cross_reference: MetaCyc:GLT
has exact synonym: L-glutamate(1-)
has exact synonym: hydrogen L-glutamate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-ammoniopentanedioate
has_related_synonym: L-glutamate
has_related_synonym: L-glutamic acid monoanion
has_related_synonym: L-glutamic acid, ion(1-)
id: CHEBI:29985
in subset: 3 STAR

D-glutamate(1-)
type: Class
subclass of: glutamate(1-)
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-glutamate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-glutamic acid
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-glutamate(1-)
definition: An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group
imported from: chebi.owl
charge: -1
formula: C5H8NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1
inchikey: WHUUTDBJXJRKMK-GSVOUGTGSA-M
mass: 146.12136
monoisotopicmass: 146.04588
smiles: [NH3+][C@H](CCC([O-])=O)C([O-])=O
has_alternative_id: CHEBI:12979
has_alternative_id: CHEBI:21022
database_cross_reference: Beilstein:8319427
database_cross_reference: MetaCyc:D-GLT
has exact synonym: D-glutamate(1-)
has exact synonym: hydrogen D-glutamate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-ammoniopentanedioate
has_related_synonym: D-glutamate
has_related_synonym: D-glutamic acid monoanion
id: CHEBI:29986
in subset: 3 STAR

glutamate(2-)
type: Class
subclass of: dicarboxylic acid dianion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: glutamate(1-)
definition: A dicarboxylic acid dianion that is the conjugate base of glutamate(1-).
imported from: chebi.owl
charge: -2
formula: C5H7NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2
inchikey: WHUUTDBJXJRKMK-UHFFFAOYSA-L
mass: 145.11342
monoisotopicmass: 145.03860
smiles: NC(CCC([O-])=O)C([O-])=O
database_cross_reference: Beilstein:4134100
database_cross_reference: Gmelin:327903
database_cross_reference: Reaxys:4134100
has exact synonym: 2-aminopentanedioate
has exact synonym: glutamate
has exact synonym: glutamate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: glutamic acid dianion
id: CHEBI:29987
in subset: 3 STAR

L-glutamate(2-)
type: Class
subclass of: glutamate(2-)
subclass of: CHEBI_59814
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-glutamate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-glutamate(2-)
definition: An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid.
imported from: chebi.owl
charge: -2
formula: C5H7NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m0/s1
inchikey: WHUUTDBJXJRKMK-VKHMYHEASA-L
mass: 145.11342
monoisotopicmass: 145.03860
smiles: N[C@@H](CCC([O-])=O)C([O-])=O
database_cross_reference: Gmelin:327905
has exact synonym: (2S)-2-aminopentanedioate
has exact synonym: L-glutamate
has exact synonym: L-glutamate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: L-glutamic acid dianion
id: CHEBI:29988
in subset: 3 STAR

D-glutamate(2-)
type: Class
subclass of: glutamate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-glutamate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-glutamate(2-)
imported from: chebi.owl
charge: -2
formula: C5H7NO4
inchi: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m1/s1
inchikey: WHUUTDBJXJRKMK-GSVOUGTGSA-L
mass: 145.11342
monoisotopicmass: 145.03860
smiles: N[C@H](CCC([O-])=O)C([O-])=O
database_cross_reference: Beilstein:8143000
database_cross_reference: Gmelin:327904
has exact synonym: (2R)-2-aminopentanedioate
has exact synonym: D-glutamate
has exact synonym: D-glutamate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: D-glutamic acid dianion
id: CHEBI:29989
in subset: 3 STAR

aspartate(2-)
type: Class
subclass of: aspartate
subclass of: CHEBI_61336
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: aspartate(1-)
definition: A C4-dicarboxylate that is the dianion obtained by the deprotonation of both the carboxy groups of aspartic acid.
imported from: chebi.owl
charge: -2
formula: C4H5NO4
inchi: InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/p-2
inchikey: CKLJMWTZIZZHCS-UHFFFAOYSA-L
mass: 131.08684
monoisotopicmass: 131.02295
smiles: NC(CC([O-])=O)C([O-])=O
has exact synonym: 2-aminobutanedioate
has exact synonym: aspartate
has exact synonym: aspartate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-aminosuccinate
has_related_synonym: aspartic acid dianion
id: CHEBI:29995
in subset: 3 STAR

acetate
type: Class
subclass of: CHEBI_35757
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: acetic acid
definition: A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
imported from: chebi.owl
charge: -1
formula: C2H3O2
inchi: InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1
inchikey: QTBSBXVTEAMEQO-UHFFFAOYSA-M
mass: 59.04402
monoisotopicmass: 59.01385
smiles: CC([O-])=O
has_alternative_id: CHEBI:13704
has_alternative_id: CHEBI:22165
has_alternative_id: CHEBI:40480
database_cross_reference: Beilstein:1901470
database_cross_reference: CAS:71-50-1
database_cross_reference: DrugBank:DB03166
database_cross_reference: Gmelin:1379
database_cross_reference: KEGG:C00033
database_cross_reference: MetaCyc:ACET
database_cross_reference: PDBeChem:ACT
database_cross_reference: PMID:17190852
database_cross_reference: PMID:22211106
database_cross_reference: PMID:22371380
database_cross_reference: Reaxys:1901470
database_cross_reference: UM-BBD_compID:c0050
database_cross_reference: Wikipedia:Acetate
has exact synonym: acetate
has_obo_namespace: chebi_ontology
has_related_synonym: ACETATE ION
has_related_synonym: Azetat
has_related_synonym: CH3-COO(-)
has_related_synonym: Ethanoat
has_related_synonym: MeCO2 anion
has_related_synonym: acetic acid, ion(1-)
has_related_synonym: ethanoate
id: CHEBI:30089
in subset: 3 STAR

diazene
type: Class
subclass of: nitrogen hydride
subclass of: Restriction
  on property: is conjugate acid of
  some values from: diazenide
imported from: chebi.owl
charge: 0
formula: H2N2
inchi: InChI=1S/H2N2/c1-2/h1-2H
inchikey: RAABOESOVLLHRU-UHFFFAOYSA-N
mass: 30.02936
monoisotopicmass: 30.02180
smiles: N=N
database_cross_reference: CAS:3618-05-1
database_cross_reference: KEGG:C05360
has exact synonym: diazene
has_obo_namespace: chebi_ontology
has_related_synonym: Diimide
has_related_synonym: HN=NH
id: CHEBI:30096
in subset: 3 STAR

diazenide
type: Class
subclass of: nitrogen hydride
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dinitride(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: diazene
imported from: chebi.owl
charge: -1
formula: HN2
inchi: InChI=1S/HN2/c1-2/h1H/q-1
inchikey: XSCXGOPPNHTWEF-UHFFFAOYSA-N
mass: 29.02142
monoisotopicmass: 29.01452
smiles: N=[N-]
has exact synonym: diazenide
has_obo_namespace: chebi_ontology
has_related_synonym: N=NH(-)
id: CHEBI:30103
in subset: 3 STAR

azo group
type: Class
subclass of: inorganic group
subclass of: Restriction
  on property: is substituent group from
  some values from: diazene
imported from: chebi.owl
charge: 0
formula: N2
mass: 28.01348
monoisotopicmass: 28.00615
smiles: N(=N/*)\*
has exact synonym: diazenediyl
has_obo_namespace: chebi_ontology
has_related_synonym: -N=N-
has_related_synonym: azo
has_related_synonym: diazene-1,2-diyl
id: CHEBI:30106
in subset: 3 STAR

isopropyl group
type: Class
subclass of: alkyl group
subclass of: CHEBI_50325
subclass of: Restriction
  on property: is substituent group from
  some values from: propane
imported from: chebi.owl
charge: 0
formula: C3H7
mass: 43.08768
monoisotopicmass: 43.05478
smiles: CC(*)C
has exact synonym: isopropyl
has exact synonym: propan-2-yl
has_obo_namespace: chebi_ontology
has_related_synonym: (CH3)2CH-
has_related_synonym: -CH(CH3)2
has_related_synonym: 1-methylethyl
has_related_synonym: iPr
has_related_synonym: valine side-chain
id: CHEBI:30353
in subset: 3 STAR

isobutyl group
type: Class
subclass of: alkyl group
subclass of: CHEBI_50325
subclass of: Restriction
  on property: is substituent group from
  some values from: isobutane
imported from: chebi.owl
charge: 0
formula: C4H9
mass: 57.11426
monoisotopicmass: 57.07043
smiles: CC(C)C*
has exact synonym: 2-methylpropan-1-ido
has exact synonym: 2-methylpropyl
has exact synonym: isobutyl
has_obo_namespace: chebi_ontology
has_related_synonym: (CH3)2CH-CH2-
has_related_synonym: -CH2-CH(CH3)2
has_related_synonym: iBu
has_related_synonym: leucine side-chain
id: CHEBI:30356
in subset: 3 STAR

isobutane
type: Class
subclass of: gas molecular entity
subclass of: alkane
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78017
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78433
definition: An alkane that is propane substituted by a methyl group at position 2.
imported from: chebi.owl
charge: 0
formula: C4H10
inchi: InChI=1S/C4H10/c1-4(2)3/h4H,1-3H3
inchikey: NNPPMTNAJDCUHE-UHFFFAOYSA-N
mass: 58.12220
monoisotopicmass: 58.07825
smiles: CC(C)C
database_cross_reference: Beilstein:1730720
database_cross_reference: CAS:75-28-5
database_cross_reference: Gmelin:1301
database_cross_reference: KEGG:D04623
database_cross_reference: PMID:24179026
database_cross_reference: PMID:24464945
database_cross_reference: Reaxys:1730720
database_cross_reference: Wikipedia:Isobutane
has exact synonym: 2-methylpropane
has exact synonym: isobutane
has_obo_namespace: chebi_ontology
has_related_synonym: (CH3)2CH-CH3
has_related_synonym: E943b
has_related_synonym: R-600a
id: CHEBI:30363
in subset: 3 STAR

Benztropine
type: Class
subclass of: CHEBI_50996
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P23975
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR P31645
subclass of: Restriction
  on property: chemical inhibits protein
  some values from: PR Q01959
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P11229
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR P35367
subclass of: Restriction
  on property: has role
  some values from: oneirogen
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48407
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48876
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50370
subclass of: Restriction
  on property: has role
  some values from: CHEBI_66956
has_RxCUI: 1424
definition: Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
definition source: https://www.drugbank.ca/drugs/DB00245
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C21H25NO
inchi: InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
inchikey: GIJXKZJWITVLHI-PMOLBWCYSA-N
mass: 307.42930
monoisotopicmass: 307.19361
has_alternative_id: CHEBI:661238
database_cross_reference: Beilstein:90688
database_cross_reference: CAS:86-13-5
database_cross_reference: ChEMBL:661238
database_cross_reference: ChemIDplus:86-13-5
database_cross_reference: DrugBank:DB00245
database_cross_reference: Drug_Central:333
database_cross_reference: KEGG COMPOUND:86-13-5
database_cross_reference: KEGG COMPOUND:C06846
database_cross_reference: KEGG DRUG:D07511
database_cross_reference: KEGG:C06846
database_cross_reference: KEGG:D07511
database_cross_reference: NIST Chemistry WebBook:86-13-5
database_cross_reference: Patent:US2595405
database_cross_reference: Wikipedia:Benzatropine
has exact synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
has exact synonym: Benzatropine
has_obo_namespace: chebi_ontology
has_related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane
has_related_synonym: 3alpha-(diphenylmethoxy)tropane
has_related_synonym: 3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
has_related_synonym: 3endo-benzhydryloxytropane
has_related_synonym: Benztropine
has_related_synonym: C21H25NO
has_related_synonym: InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+
has_related_synonym: InChIKey=GIJXKZJWITVLHI-PMOLBWCYSA-N
has_related_synonym: benzatropina
has_related_synonym: benzatropine
has_related_synonym: benzatropinum
has_related_synonym: benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether
has_related_synonym: tropine benzohydryl ether
id: CHEBI:3048
in subset: 3 STAR
label: benzatropine

sulfonium
type: Class
subclass of: sulfonium compound
subclass of: sulfur hydride
subclass of: CHEBI_50313
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hydrogen sulfide
imported from: chebi.owl
charge: +1
formula: H3S
inchi: InChI=1S/H2S/h1H2/p+1
inchikey: RWSOTUBLDIXVET-UHFFFAOYSA-O
mass: 35.08982
monoisotopicmass: 34.99500
smiles: [H][S+]([H])[H]
database_cross_reference: CAS:18155-21-0
database_cross_reference: Gmelin:307
has exact synonym: sulfanium
has exact synonym: sulfonium
has exact synonym: trihydridosulfur(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: H3S(+)
has_related_synonym: H3S+
has_related_synonym: [SH3](+)
has_related_synonym: sulphonium
id: CHEBI:30488
in subset: 3 STAR

benzatropine mesylate
type: Class
subclass of: CHEBI_38037
subclass of: Restriction
  on property: has part
  some values from: Benztropine
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48407
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50370
definition: The methanesulfonate salt of benzatropine. An acetylcholine receptor antagonist, it is used in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
definition source: PMID: 26202243; PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C22H29NO4S
inchi: InChI=1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;
inchikey: CPFJLLXFNPCTDW-BWSPSPBFSA-N
mass: 403.53500
monoisotopicmass: 403.18173
smiles: CS([O-])(=O)=O.[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)[NH+]2C)OC(c1ccccc1)c1ccccc1
database_cross_reference: Beilstein:3826475
database_cross_reference: CAS:132-17-2
database_cross_reference: DrugBank:DB00245
database_cross_reference: KEGG:D00778
database_cross_reference: Patent:US2595405
has exact synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate
has_obo_namespace: chebi_ontology
has_related_synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane methanesulfonate
has_related_synonym: 3-diphenylmethoxytropane mesylate
has_related_synonym: 3-diphenylmethoxytropane methanesulfonate
has_related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane mesylate
has_related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane methanesulfonate
has_related_synonym: 3alpha-(diphenylmethoxy)tropane mesylate
has_related_synonym: 3alpha-(diphenylmethoxy)tropane methanesulfonate
has_related_synonym: 3endo-benzhydryloxytropane mesylate
has_related_synonym: 3endo-benzhydryloxytropane methanesulphonate
has_related_synonym: benzatropine methanesulfonate
has_related_synonym: benztropine mesilate
has_related_synonym: benztropine mesylate
has_related_synonym: benztropine methanesulfonate
has_related_synonym: tropine benzohydryl ether mesylate
has_related_synonym: tropine benzohydryl ether methanesulphonate
id: CHEBI:3049
in subset: 3 STAR

Berbamine
type: Class
subclass of: bisbenzylisoquinoline alkaloid
subclass of: isoquinolines
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
definition source: PMID: 32366720; PMID: 29305616
imported from: chebi.owl
charge: 0
formula: C37H40N2O6
inchi: InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29+/m0/s1
inchikey: DFOCUWZXJBAUSQ-URLMMPGGSA-N
mass: 608.725
monoisotopicmass: 608.28864
database_cross_reference: CAS:478-61-5
database_cross_reference: KEGG:C09357
database_cross_reference: KNApSAcK:C00001817
has exact synonym: Berbamine
has_obo_namespace: chebi_ontology
id: CHEBI:3063
in subset: 2 STAR

benzoic acid
type: Class
subclass of: benzoic acids
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64996
subclass of: Restriction
  on property: has role
  some values from: CHEBI_65001
subclass of: Restriction
  on property: has role
  some values from: CHEBI_65256
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76967
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84735
subclass of: Restriction
  on property: has role
  some values from: CHEBI_88188
subclass of: Restriction
  on property: is conjugate acid of
  some values from: benzoate
definition: A compound comprising a benzene ring core carrying a carboxylic acid substituent.
imported from: chebi.owl
charge: 0
formula: C7H6O2
inchi: InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
inchikey: WPYMKLBDIGXBTP-UHFFFAOYSA-N
mass: 122.12130
monoisotopicmass: 122.03678
smiles: OC(=O)c1ccccc1
has_alternative_id: CHEBI:22722
has_alternative_id: CHEBI:3029
has_alternative_id: CHEBI:41051
database_cross_reference: Beilstein:636131
database_cross_reference: CAS:65-85-0
database_cross_reference: DrugBank:DB03793
database_cross_reference: Drug_Central:4664
database_cross_reference: Gmelin:2946
database_cross_reference: HMDB:HMDB0001870
database_cross_reference: KEGG:C00180
database_cross_reference: KEGG:C00539
database_cross_reference: KEGG:D00038
database_cross_reference: KNApSAcK:C00000207
database_cross_reference: LINCS:LSM-37118
database_cross_reference: MetaCyc:BENZOATE
database_cross_reference: PDBeChem:BEZ
database_cross_reference: PMID:16728954
database_cross_reference: PMID:17439666
database_cross_reference: PMID:18314336
database_cross_reference: PPDB:1475
database_cross_reference: Reaxys:636131
database_cross_reference: Wikipedia:Benzoic_Acid
database_cross_reference: YMDB:YMDB02301
has exact synonym: BENZOIC ACID
has exact synonym: Benzoic acid
has exact synonym: benzoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Aromatic carboxylic acid
has_related_synonym: Benzenecarboxylic acid
has_related_synonym: Benzeneformic acid
has_related_synonym: Benzenemethanoic acid
has_related_synonym: Benzoesaeure
has_related_synonym: Dracylic acid
has_related_synonym: E210
has_related_synonym: Phenylcarboxylic acid
has_related_synonym: Phenylformic acid
has_related_synonym: acide benzoique
id: CHEBI:30746
in subset: 3 STAR

formic acid
type: Class
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: has role
  some values from: antibacterial agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_46787
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48356
subclass of: Restriction
  on property: has role
  some values from: CHEBI_74783
subclass of: Restriction
  on property: is conjugate acid of
  some values from: formate
definition: The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
imported from: chebi.owl
charge: 0
formula: CH2O2
inchi: InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)
inchikey: BDAGIHXWWSANSR-UHFFFAOYSA-N
mass: 46.02538
monoisotopicmass: 46.00548
smiles: [H]C(O)=O
has_alternative_id: CHEBI:24082
has_alternative_id: CHEBI:42460
has_alternative_id: CHEBI:5145
database_cross_reference: BPDB:1749
database_cross_reference: Beilstein:1209246
database_cross_reference: CAS:64-18-6
database_cross_reference: DrugBank:DB01942
database_cross_reference: Gmelin:1008
database_cross_reference: HMDB:HMDB0000142
database_cross_reference: KEGG:C00058
database_cross_reference: KNApSAcK:C00001182
database_cross_reference: LIPID_MAPS_instance:LMFA01010040
database_cross_reference: MetaCyc:FORMATE
database_cross_reference: PDBeChem:FMT
database_cross_reference: PMID:12591956
database_cross_reference: PMID:14637377
database_cross_reference: PMID:15811469
database_cross_reference: PMID:16120414
database_cross_reference: PMID:16185830
database_cross_reference: PMID:16222862
database_cross_reference: PMID:16230297
database_cross_reference: PMID:16445901
database_cross_reference: PMID:16465784
database_cross_reference: PMID:18034701
database_cross_reference: PMID:18397576
database_cross_reference: PMID:22080171
database_cross_reference: PMID:22280475
database_cross_reference: PMID:22304812
database_cross_reference: PMID:22385261
database_cross_reference: PMID:22447125
database_cross_reference: PMID:22483350
database_cross_reference: PMID:22499553
database_cross_reference: PMID:22540994
database_cross_reference: PMID:22606986
database_cross_reference: PMID:22622393
database_cross_reference: PMID:3946945
database_cross_reference: PMID:7361809
database_cross_reference: Patent:CN101481304
database_cross_reference: Reaxys:1209246
database_cross_reference: Wikipedia:Formic_acid
has exact synonym: FORMIC ACID
has exact synonym: Formic acid
has exact synonym: formic acid
has_obo_namespace: chebi_ontology
has_related_synonym: Acide formique
has_related_synonym: Ameisensaeure
has_related_synonym: H-COOH
has_related_synonym: HCO2H
has_related_synonym: HCOOH
has_related_synonym: Methanoic acid
has_related_synonym: aminic acid
has_related_synonym: bilorin
has_related_synonym: formylic acid
has_related_synonym: hydrogen carboxylic acid
has_related_synonym: methoic acid
id: CHEBI:30751
in subset: 3 STAR

salicylate
type: Class
subclass of: monohydroxybenzoate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate base of
  some values from: salicylic acid
definition: A monohydroxybenzoate that is the conjugate base of salicylic acid.
imported from: chebi.owl
charge: -1
formula: C7H5O3
inchi: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)/p-1
inchikey: YGSDEFSMJLZEOE-UHFFFAOYSA-M
mass: 137.11280
monoisotopicmass: 137.02442
smiles: Oc1ccccc1C([O-])=O
has_alternative_id: CHEBI:15061
has_alternative_id: CHEBI:26595
database_cross_reference: Beilstein:3605209
database_cross_reference: CAS:63-36-5
database_cross_reference: Gmelin:3417
database_cross_reference: KEGG:C00805
database_cross_reference: PMID:16669002
database_cross_reference: PMID:16934829
database_cross_reference: Reaxys:3605209
database_cross_reference: UM-BBD_compID:c0043
has exact synonym: 2-hydroxybenzoate
has exact synonym: Salicylate
has exact synonym: salicylate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-hydroxybenzoic acid ion(1-)
has_related_synonym: o-hydroxybenzoate
has_related_synonym: sal
id: CHEBI:30762
in subset: 3 STAR

propionic acid
type: Class
subclass of: saturated fatty acid
subclass of: short-chain fatty acid
subclass of: Restriction
  on property: has role
  some values from: CHEBI_86327
subclass of: Restriction
  on property: is conjugate acid of
  some values from: propionate
definition: A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.
imported from: chebi.owl
charge: 0
formula: C3H6O2
inchi: InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)
inchikey: XBDQKXXYIPTUBI-UHFFFAOYSA-N
mass: 74.07850
monoisotopicmass: 74.03678
smiles: CCC(O)=O
has_alternative_id: CHEBI:26304
has_alternative_id: CHEBI:45227
has_alternative_id: CHEBI:8476
database_cross_reference: Beilstein:506071
database_cross_reference: CAS:79-09-4
database_cross_reference: DrugBank:DB03766
database_cross_reference: Gmelin:1821
database_cross_reference: KEGG:C00163
database_cross_reference: KEGG:D02310
database_cross_reference: LIPID_MAPS_instance:LMFA01010003
database_cross_reference: PDBeChem:PPI
database_cross_reference: PMID:15868474
database_cross_reference: PMID:1628870
database_cross_reference: PMID:16763906
database_cross_reference: PPDB:1341
has exact synonym: Propionic acid
has exact synonym: propanoic acid
has exact synonym: propionic acid
has_obo_namespace: chebi_ontology
has_related_synonym: CH3-CH2-COOH
has_related_synonym: PA
has_related_synonym: PROPANOIC ACID
has_related_synonym: Propanoic acid
has_related_synonym: Propionsaeure
has_related_synonym: acide propanoique
has_related_synonym: acide propionique
has_related_synonym: carboxyethane
has_related_synonym: ethanecarboxylic acid
has_related_synonym: ethylformic acid
has_related_synonym: metacetonic acid
has_related_synonym: methylacetic acid
has_related_synonym: propioic acid
has_related_synonym: propoic acid
has_related_synonym: pseudoacetic acid
id: CHEBI:30768
in subset: 3 STAR

butyric acid
type: Class
subclass of: fatty acid 4:0
subclass of: CHEBI_39418
subclass of: Restriction
  on property: has role
  some values from: Mycoplasma genitalium metabolite
subclass of: Restriction
  on property: has role
  some values from: CHEBI_84087
subclass of: Restriction
  on property: is conjugate acid of
  some values from: butyrate
definition: A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
imported from: chebi.owl
charge: 0
formula: C4H8O2
inchi: InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
inchikey: FERIUCNNQQJTOY-UHFFFAOYSA-N
mass: 88.10510
monoisotopicmass: 88.05243
smiles: CCCC(O)=O
has_alternative_id: CHEBI:113450
has_alternative_id: CHEBI:22948
has_alternative_id: CHEBI:3234
has_alternative_id: CHEBI:41208
database_cross_reference: Beilstein:906770
database_cross_reference: CAS:107-92-6
database_cross_reference: DrugBank:DB03568
database_cross_reference: Gmelin:26242
database_cross_reference: HMDB:HMDB0000039
database_cross_reference: KEGG:C00246
database_cross_reference: KNApSAcK:C00001180
database_cross_reference: LIPID_MAPS_instance:LMFA01010004
database_cross_reference: MetaCyc:BUTYRIC_ACID
database_cross_reference: PDBeChem:BUA
database_cross_reference: PMID:10736622
database_cross_reference: PMID:10956204
database_cross_reference: PMID:11201044
database_cross_reference: PMID:11208715
database_cross_reference: PMID:11238216
database_cross_reference: PMID:11305323
database_cross_reference: PMID:12068484
database_cross_reference: PMID:13678314
database_cross_reference: PMID:14962641
database_cross_reference: PMID:1542095
database_cross_reference: PMID:15809727
database_cross_reference: PMID:15810631
database_cross_reference: PMID:15938880
database_cross_reference: PMID:19318247
database_cross_reference: PMID:19366864
database_cross_reference: PMID:19703412
database_cross_reference: PMID:21699495
database_cross_reference: PMID:22038864
database_cross_reference: PMID:22194341
database_cross_reference: PMID:22322557
database_cross_reference: PMID:22339023
database_cross_reference: PMID:22466881
database_cross_reference: Reaxys:906770
database_cross_reference: Wikipedia:Butyric_acid
has exact synonym: Butyric acid
has exact synonym: butanoic acid
has exact synonym: butyric acid
has_obo_namespace: chebi_ontology
has_related_synonym: 1-butanoic acid
has_related_synonym: 1-butyric acid
has_related_synonym: 1-propanecarboxylic acid
has_related_synonym: 4:0
has_related_synonym: BUTANOIC ACID
has_related_synonym: Butanoate
has_related_synonym: Butanoic acid
has_related_synonym: Buttersaeure
has_related_synonym: C4:0
has_related_synonym: CH3-[CH2]2-COOH
has_related_synonym: acide butanoique
has_related_synonym: acide butyrique
has_related_synonym: butanic acid
has_related_synonym: butoic acid
has_related_synonym: ethylacetic acid
has_related_synonym: n-butanoic acid
has_related_synonym: n-butyric acid
has_related_synonym: propanecarboxylic acid
has_related_synonym: propylformic acid
id: CHEBI:30772
in subset: 3 STAR

hexanoic acid
type: Class
subclass of: CHEBI_39418
subclass of: CHEBI_59554
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: hexanoate
definition: A C6, straight-chain saturated fatty acid.
imported from: chebi.owl
charge: 0
formula: C6H12O2
inchi: InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)
inchikey: FUZZWVXGSFPDMH-UHFFFAOYSA-N
mass: 116.15830
monoisotopicmass: 116.08373
smiles: CCCCCC(O)=O
has_alternative_id: CHEBI:24571
has_alternative_id: CHEBI:40213
has_alternative_id: CHEBI:5702
database_cross_reference: Beilstein:773837
database_cross_reference: CAS:142-62-1
database_cross_reference: ECMDB:ECMDB21229
database_cross_reference: Gmelin:185066
database_cross_reference: HMDB:HMDB0000535
database_cross_reference: KEGG:C01585
database_cross_reference: KNApSAcK:C00001218
database_cross_reference: LIPID_MAPS_instance:LMFA01010006
database_cross_reference: MetaCyc:HEXANOATE
database_cross_reference: PDBeChem:6NA
database_cross_reference: PMID:10685018
database_cross_reference: PMID:1556177
database_cross_reference: PMID:24357269
database_cross_reference: PMID:24924750
database_cross_reference: Reaxys:773837
database_cross_reference: Wikipedia:Hexanoic_acid
database_cross_reference: YMDB:YMDB01424
has exact synonym: HEXANOIC ACID
has exact synonym: Hexanoic acid
has exact synonym: hexanoic acid
has_obo_namespace: chebi_ontology
has_related_synonym: 1-hexanoic acid
has_related_synonym: 1-pentanecarboxylic acid
has_related_synonym: 6:0
has_related_synonym: C6:0
has_related_synonym: CH3-[CH2]4-COOH
has_related_synonym: Hexanoate
has_related_synonym: Hexylic acid
has_related_synonym: Pentanecarboxylic acid
has_related_synonym: butylacetic acid
has_related_synonym: caproic acid
has_related_synonym: capronic acid
has_related_synonym: hexoic acid
has_related_synonym: n-Caproic acid
has_related_synonym: n-hexanoic acid
has_related_synonym: n-hexoic acid
has_related_synonym: n-hexylic acid
has_related_synonym: pentiformic acid
has_related_synonym: pentylformic acid
id: CHEBI:30776
in subset: 3 STAR

oleate
type: Class
subclass of: octadec-9-enoate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: oleic acid
definition: A C18, long straight-chain monounsaturated fatty acid anion; and the conjugate base of oleic acid, arising from deprotonation of the carboxylic acid group.
imported from: chebi.owl
charge: -1
formula: C18H33O2
inchi: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/p-1/b10-9-
inchikey: ZQPPMHVWECSIRJ-KTKRTIGZSA-M
mass: 281.45342
monoisotopicmass: 281.24860
smiles: CCCCCCCC\C=C/CCCCCCCC([O-])=O
has_alternative_id: CHEBI:14684
has_alternative_id: CHEBI:25663
database_cross_reference: Beilstein:1913148
database_cross_reference: CAS:115-06-0
database_cross_reference: Gmelin:344067
database_cross_reference: PMID:12429352
database_cross_reference: Reaxys:1913148
has exact synonym: (9Z)-octadec-9-enoate
has_obo_namespace: chebi_ontology
has_related_synonym: (9Z)-octadecenoate
has_related_synonym: (Z)-9-octadecenoic acid, ion(1-)
has_related_synonym: Oleat
has_related_synonym: cis-9-octadecenoate
has_related_synonym: oleic acid anion
id: CHEBI:30823
in subset: 3 STAR

alcohol
type: Class
subclass of: organic hydroxy compound
definition: A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: O[*]
has_alternative_id: CHEBI:13804
has_alternative_id: CHEBI:22288
has_alternative_id: CHEBI:2553
database_cross_reference: KEGG COMPOUND:C00069
database_cross_reference: KEGG:C00069
has exact synonym: Alcohol
has exact synonym: alcohols
has_obo_namespace: chebi_ontology
has_related_synonym: CHOR3
has_related_synonym: HOR
has_related_synonym: OC([*])([*])[*]
has_related_synonym: an alcohol
id: CHEBI:30879
in subset: 3 STAR

biguanide
type: Class
subclass of: guanidines
imported from: chebi.owl
charge: 0
formula: C2H7N5
inchi: InChI=1S/C2H7N5/c3-1(4)7-2(5)6/h(H7,3,4,5,6,7)
inchikey: XNCOSPRUTUOJCJ-UHFFFAOYSA-N
mass: 101.11068
monoisotopicmass: 101.07015
smiles: NC(=N)NC(N)=N
database_cross_reference: Beilstein:507183
database_cross_reference: CAS:56-03-1
database_cross_reference: Gmelin:240093
database_cross_reference: KEGG:C07672
has exact synonym: 1,2,3-triimidodicarbonic diamide
has exact synonym: Biguanide
has exact synonym: biguanide
has_obo_namespace: chebi_ontology
has_related_synonym: H2N-C(=NH)-NH-C(=NH)-NH2
has_related_synonym: Hbig
has_related_synonym: imidodicarbonimidic diamide
id: CHEBI:3095
in subset: 3 STAR

valerate
type: Class
subclass of: CHEBI_58951
subclass of: CHEBI_58954
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate base of
  some values from: valeric acid
definition: A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals.
imported from: chebi.owl
charge: -1
formula: C5H9O2
inchi: InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)/p-1
inchikey: NQPDZGIKBAWPEJ-UHFFFAOYSA-M
mass: 101.12376
monoisotopicmass: 101.06080
smiles: CCCCC([O-])=O
has_alternative_id: CHEBI:14751
has_alternative_id: CHEBI:25890
database_cross_reference: Beilstein:3903735
database_cross_reference: CAS:10023-74-2
database_cross_reference: Gmelin:325619
database_cross_reference: PMID:17314444
database_cross_reference: PMID:18783570
database_cross_reference: Reaxys:3903735
has exact synonym: pentanoate
has_obo_namespace: chebi_ontology
has_related_synonym: CH3-[CH2]3-COO(-)
has_related_synonym: n-propylacetate
has_related_synonym: pentanoate
has_related_synonym: pentanoic acid, ion(1-)
id: CHEBI:31011
in subset: 3 STAR

Ciclesonide
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical has protein target as agonist
  some values from: PR P04150
subclass of: Restriction
  on property: chemical binds protein
  some values from: PR P08185
subclass of: Restriction
  on property: chemical modulates response in vitro against virus
  some values from: NCBITaxon_694009
definition source: PMID: 32366720
definition source: https://www.drugbank.ca/drugs/DB01410
imported from: chebi.owl
charge: 0
formula: C32H44O7
inchi: InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
inchikey: LUKZNWIVRBCLON-GXOBDPJESA-N
mass: 540.689
monoisotopicmass: 540.30870
database_cross_reference: CAS:126544-47-6
database_cross_reference: Drug_Central:633
database_cross_reference: KEGG:D01703
has exact synonym: Ciclesonide
has_obo_namespace: chebi_ontology
has_related_synonym: alvesco
has_related_synonym: omnaris
id: CHEBI:31397
in subset: 2 STAR

gemcitabine hydrochloride
type: Class
subclass of: CHEBI_36807
subclass of: CHEBI_37143
subclass of: Restriction
  on property: has part
  some values from: gemcitabine
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: radiosensitizing agent
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antimetabolite
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: immunosuppressive agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
subclass of: Restriction
  on property: has role
  some values from: CHEBI_74213
definition: A 2'-deoxycytidine hydrochloriode having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine hydrochloride is used in the treatment of various carcinomas, including non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C9H11F2N3O4.HCl
formula: C9H12ClF2N3O4
inchi: InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
inchikey: OKKDEIYWILRZIA-OSZBKLCCSA-N
mass: 299.65900
monoisotopicmass: 299.04844
database_cross_reference: Beilstein:5386970
database_cross_reference: CAS:122111-03-9
database_cross_reference: DrugBank:DB00441
database_cross_reference: KEGG:D01155
has exact synonym: 2'-deoxy-2',2'-difluorocytidine hydrochloride
has_obo_namespace: chebi_ontology
has_related_synonym: 2',2'-Difluorodeoxycytidine monohydrochloride
has_related_synonym: 2'-Deoxy-2',2'-difluorocytidine monohydrochloride
has_related_synonym: Gemcitabine HCl
id: CHEBI:31647
in subset: 3 STAR

teprenone
type: Class
subclass of: terpene ketone
subclass of: CHEBI_51867
subclass of: Restriction
  on property: has part
  some values from: geranylgeranyl group
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: CHEBI_49201
subclass of: Restriction
  on property: has role
  some values from: CHEBI_62868
subclass of: Restriction
  on property: has role
  some values from: CHEBI_63726
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76595
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77307
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78606
definition: A terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio).
definition source: PMID: 30711575
imported from: chebi.owl
charge: 0
formula: C23H38O
inchi: InChI=1S/C23H38O/c1-19(2)11-7-12-20(3)13-8-14-21(4)15-9-16-22(5)17-10-18-23(6)24/h11,13,15,17H,7-10,12,14,16,18H2,1-6H3/b20-13+,21-15+,22-17?
inchikey: HUCXKZBETONXFO-AJDZVAQLSA-N
mass: 330.54720
monoisotopicmass: 330.29227
database_cross_reference: CAS:6809-52-5
database_cross_reference: Drug_Central:2596
database_cross_reference: KEGG:C13297
database_cross_reference: KEGG:D01827
database_cross_reference: PMID:21645219
database_cross_reference: PMID:22004457
database_cross_reference: PMID:22548767
database_cross_reference: PMID:23229517
database_cross_reference: PMID:23289389
database_cross_reference: PMID:23684147
database_cross_reference: PMID:23792203
database_cross_reference: PMID:23942364
database_cross_reference: PMID:24008351
database_cross_reference: PMID:24098472
database_cross_reference: PMID:24531083
database_cross_reference: PMID:24573719
database_cross_reference: PMID:24582814
database_cross_reference: PMID:24631258
database_cross_reference: PMID:24633659
database_cross_reference: PMID:24695789
database_cross_reference: PMID:24737026
database_cross_reference: Reaxys:8717724
has exact synonym: (9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
has_obo_namespace: chebi_ontology
has_related_synonym: Geranylgeranylacetone
has_related_synonym: Selbex
has_related_synonym: teprenona
has_related_synonym: teprenone
has_related_synonym: teprenonum
id: CHEBI:31649
in subset: 3 STAR

imatinib methanesulfonate
type: Class
subclass of: CHEBI_38037
subclass of: Restriction
  on property: has part
  some values from: CHEBI_45783
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_38637
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
definition: A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C29H31N7O.CH4O3S
formula: C30H35N7O4S
inchi: InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
inchikey: YLMAHDNUQAMNNX-UHFFFAOYSA-N
mass: 589.70968
monoisotopicmass: 589.24712
database_cross_reference: Beilstein:10229624
database_cross_reference: CAS:220127-57-1
database_cross_reference: DrugBank:DB00619
database_cross_reference: HMDB:HMDB0014757
database_cross_reference: KEGG:D01441
database_cross_reference: PMID:12047970
database_cross_reference: PMID:12616857
database_cross_reference: PMID:12669406
database_cross_reference: PMID:12975485
database_cross_reference: PMID:14760091
database_cross_reference: PMID:15059881
database_cross_reference: PMID:15161340
database_cross_reference: PMID:15206509
database_cross_reference: PMID:15250677
database_cross_reference: PMID:15601563
database_cross_reference: PMID:15727903
database_cross_reference: PMID:16570351
database_cross_reference: PMID:16805961
database_cross_reference: PMID:16835496
database_cross_reference: PMID:17212133
database_cross_reference: PMID:18422477
database_cross_reference: PMID:19073506
database_cross_reference: PMID:19258052
database_cross_reference: PMID:19508953
database_cross_reference: PMID:19542718
database_cross_reference: PMID:19568828
database_cross_reference: PMID:21084823
database_cross_reference: PMID:21333826
database_cross_reference: PMID:23462796
database_cross_reference: Patent:RU2365587
database_cross_reference: Patent:WO2004106326
database_cross_reference: Patent:WO2011161689
database_cross_reference: Patent:WO9903854
database_cross_reference: Reaxys:10229624
has exact synonym: 4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide methanesulfonate
has_obo_namespace: chebi_ontology
has_related_synonym: Gleevec
has_related_synonym: Glivec
has_related_synonym: imatinib mesilate
has_related_synonym: imatinib mesylate
has_related_synonym: imatinib methansulfonate
has_related_synonym: imatinib monomesylate
id: CHEBI:31690
in subset: 3 STAR

lopinavir
type: Class
subclass of: amphetamines
subclass of: CHEBI_35779
subclass of: Restriction
  on property: chemical inhibits in vivo replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vivo replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: HIV protease inhibitor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_36044
subclass of: Restriction
  on property: has role
  some values from: CIDO_0000257
definition: A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir.
definition source: PMID: 26198719; PMID: 27344959; PMID: 26198719; PMID: 27344959; PMID: 14985565
definition source: PMID: 27344959; PMID: 26868298; PMID: 16837072
imported from: chebi.owl
charge: 0
formula: C37H48N4O5
inchi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
inchikey: KJHKTHWMRKYKJE-SUGCFTRWSA-N
mass: 628.80080
monoisotopicmass: 628.36247
database_cross_reference: CAS:192725-17-0
database_cross_reference: DrugBank:DB01601
database_cross_reference: Drug_Central:1601
database_cross_reference: HMDB:HMDB0015539
database_cross_reference: KEGG:C12871
database_cross_reference: KEGG:D01425
database_cross_reference: LINCS:LSM-6027
database_cross_reference: PDBeChem:AB1
database_cross_reference: PMID:24014186
database_cross_reference: PMID:24518130
database_cross_reference: PMID:24566184
database_cross_reference: PMID:24805184
database_cross_reference: PMID:24906762
database_cross_reference: PMID:24958908
database_cross_reference: PMID:25120613
database_cross_reference: Reaxys:9309881
has exact synonym: (2S)-N-[(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
has exact synonym: Lopinavir
has_obo_namespace: chebi_ontology
id: CHEBI:31781
in subset: 3 STAR

nafamostat methanesulfonate
type: Class
subclass of: guanidines
subclass of: CHEBI_36054
subclass of: CHEBI_38037
subclass of: Restriction
  on property: chemical inhibits in vitro invasion of virus
  some values from: NCBITaxon_2697049
definition source: PMID: 32020029
imported from: chebi.owl
charge: 0
formula: C19H19N5O2.2CH3O3S
mass: 539.585
monoisotopicmass: 539.11445
database_cross_reference: KEGG:D01670
has_obo_namespace: chebi_ontology
has_related_synonym: 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate
has_related_synonym: Futhan
has_related_synonym: Nafamostat mesilate
has_related_synonym: Nafamostat mesylate (TN)
id: CHEBI:31890
in subset: 2 STAR

Proscillaridin
type: Class
subclass of: CHEBI_50860
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
definition source: PMID: 32366720
imported from: chebi.owl
charge: 0
formula: C30H42O8
inchi: InChI=1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19-,20+,21-,22+,24-,25+,26+,27-,28-,29+,30-/m0/s1
inchikey: MYEJFUXQJGHEQK-ALRJYLEOSA-N
mass: 530.651
monoisotopicmass: 530.28797
database_cross_reference: CAS:466-06-8
database_cross_reference: Drug_Central:2313
database_cross_reference: KEGG:D01379
has exact synonym: Proscillaridin
has_obo_namespace: chebi_ontology
has_related_synonym: caradrin
has_related_synonym: cardiovite
has_related_synonym: desglucotransvaaline
has_related_synonym: procardin
has_related_synonym: proscillaridin A
has_related_synonym: scillacrist
id: CHEBI:32065
in subset: 2 STAR

salicylamide
type: Class
subclass of: phenols
subclass of: CHEBI_53443
subclass of: Restriction
  on property: has role
  some values from: non-narcotic analgesic
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35842
definition: The simplest member of the class of salicylamides derived from salicylic acid.
imported from: chebi.owl
charge: 0
formula: C7H7NO2
inchi: InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
inchikey: SKZKKFZAGNVIMN-UHFFFAOYSA-N
mass: 137.13600
monoisotopicmass: 137.04768
smiles: NC(=O)c1ccccc1O
database_cross_reference: Beilstein:742439
database_cross_reference: CAS:65-45-2
database_cross_reference: DrugBank:DB08797
database_cross_reference: Drug_Central:2415
database_cross_reference: Gmelin:142521
database_cross_reference: KEGG:D01811
database_cross_reference: PDBeChem:OHB
database_cross_reference: PMID:14729655
database_cross_reference: PMID:1650428
database_cross_reference: PMID:22530891
database_cross_reference: Reaxys:742439
database_cross_reference: Wikipedia:Salicylamide
has exact synonym: 2-hydroxybenzamide
has_obo_namespace: chebi_ontology
has_related_synonym: 2-Carbamoylphenol
has_related_synonym: 2-Carboxamidophenol
has_related_synonym: 2-Hydroxybenzamide
has_related_synonym: OHB
has_related_synonym: Salicylic Acid amide
has_related_synonym: o-Hydroxybenzamide
has_related_synonym: salicilamida
has_related_synonym: salicylamide
has_related_synonym: salicylamidum
id: CHEBI:32114
in subset: 3 STAR

thiethylperazine maleate
type: Class
subclass of: CHEBI_50221
subclass of: Restriction
  on property: has part
  some values from: CHEBI 9544
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
definition source: PMID: 24841273
imported from: chebi.owl
charge: 0
formula: C22H29N3S2.(C4H4O4)2
formula: C22H29N3S2.C8H8O8
formula: C30H37N3O8S2
inchi: InChI=1S/C22H29N3S2.2C4H4O4/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24;2*5-3(6)1-2-4(7)8/h4-5,7-10,17H,3,6,11-16H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
inchikey: RVBRTNPNFYFDMZ-SPIKMXEPSA-N
mass: 631.76220
monoisotopicmass: 631.20221
database_cross_reference: Beilstein:3864479
database_cross_reference: CAS:1179-69-7
database_cross_reference: DrugBank:DB00372
database_cross_reference: KEGG:D01130
has exact synonym: 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioate]
has_obo_namespace: chebi_ontology
has_related_synonym: 10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate (1:2)
has_related_synonym: 2-(Ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine dimaleate
has_related_synonym: 2-Ethylmercapto-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine dimaleate
has_related_synonym: Thiethylperazine dimaleate
has_related_synonym: Tietylperazine maleate
has_related_synonym: Torecan
id: CHEBI:32216
in subset: 3 STAR

alaninate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: is conjugate base of
  some values from: alanine
definition: An alpha-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C3H6NO2
inchi: InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/p-1
inchikey: QNAYBMKLOCPYGJ-UHFFFAOYSA-M
mass: 88.08528
monoisotopicmass: 88.04040
smiles: CC(N)C([O-])=O
database_cross_reference: Beilstein:3903719
database_cross_reference: Gmelin:101040
has exact synonym: 2-aminopropanoate
has exact synonym: alaninate
has_obo_namespace: chebi_ontology
has_related_synonym: alanine anion
id: CHEBI:32439
in subset: 3 STAR

alaninium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: has role
  some values from: metabolite
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alanine
definition: An alpha-amino-acid cation that is the conjugate acid of alanine.
imported from: chebi.owl
charge: +1
formula: C3H8NO2
inchi: InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/p+1
inchikey: QNAYBMKLOCPYGJ-UHFFFAOYSA-O
mass: 90.10116
monoisotopicmass: 90.05495
smiles: CC([NH3+])C(O)=O
database_cross_reference: Gmelin:362663
has exact synonym: 1-carboxyethanaminium
has exact synonym: alaninium
has_obo_namespace: chebi_ontology
has_related_synonym: alanine cation
id: CHEBI:32440
in subset: 3 STAR

L-cysteinate(1-)
type: Class
subclass of: cysteinate(1-)
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-cysteinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-cysteine
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-cysteine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-cysteinate(1-)
definition: The L-enantiomer of cysteinate(1-).
imported from: chebi.owl
charge: -1
formula: C3H6NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m0/s1
inchikey: XUJNEKJLAYXESH-REOHCLBHSA-M
mass: 120.15128
monoisotopicmass: 120.01247
smiles: N[C@@H](CS)C([O-])=O
database_cross_reference: Beilstein:4128886
database_cross_reference: Gmelin:325857
database_cross_reference: Reaxys:4128886
has exact synonym: L-cysteinate(1-)
has exact synonym: hydrogen L-cysteinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-mercaptopropanoate
has_related_synonym: (2R)-2-amino-3-sulfanylpropanoate
has_related_synonym: L-cysteine anion
has_related_synonym: L-cysteine monoanion
id: CHEBI:32442
in subset: 3 STAR

L-cysteinate(2-)
type: Class
subclass of: cysteinate(2-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-cysteinate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-cysteinate(2-)
definition: The L-enantiomer of cysteinate(2-).
imported from: chebi.owl
charge: -2
formula: C3H5NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m0/s1
inchikey: XUJNEKJLAYXESH-REOHCLBHSA-L
mass: 119.14334
monoisotopicmass: 119.00520
smiles: N[C@@H](C[S-])C([O-])=O
database_cross_reference: Beilstein:5921923
database_cross_reference: Gmelin:325856
database_cross_reference: Reaxys:5921923
has exact synonym: L-cysteinate
has exact synonym: L-cysteinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-sulfidopropanoate
has_related_synonym: L-cysteine dianion
id: CHEBI:32443
in subset: 3 STAR

L-cysteinium
type: Class
subclass of: cysteinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-cysteine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-cysteine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-cysteinium
definition: The L-enantiomer of cysteinium.
imported from: chebi.owl
charge: +1
formula: C3H8NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m0/s1
inchikey: XUJNEKJLAYXESH-REOHCLBHSA-O
mass: 122.16716
monoisotopicmass: 122.02703
smiles: [NH3+][C@@H](CS)C(O)=O
database_cross_reference: Gmelin:325860
has exact synonym: L-cysteinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-2-mercaptoethanaminium
has_related_synonym: (1R)-1-carboxy-2-sulfanylethanaminium
has_related_synonym: L-cysteine cation
has_related_synonym: L-cysteinium(1+)
id: CHEBI:32445
in subset: 3 STAR

D-cysteinate(1-)
type: Class
subclass of: cysteinate(1-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-cysteinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-cysteine
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-cysteine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-cysteinate(1-)
definition: The D-enantiomer of cysteinate(1-).
imported from: chebi.owl
charge: -1
formula: C3H6NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m1/s1
inchikey: XUJNEKJLAYXESH-UWTATZPHSA-M
mass: 120.15128
monoisotopicmass: 120.01247
smiles: N[C@H](CS)C([O-])=O
database_cross_reference: Gmelin:1006156
has exact synonym: D-cysteinate(1-)
has exact synonym: hydrogen D-cysteinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-mercaptopropanoate
has_related_synonym: (2S)-2-amino-3-sulfanylpropanoate
has_related_synonym: D-cysteine monoanion
id: CHEBI:32449
in subset: 3 STAR

D-cysteinate(2-)
type: Class
subclass of: cysteinate(2-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-cysteinate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-cysteinate(2-)
definition: The D-enantiomer of cysteinate(2-).
imported from: chebi.owl
charge: -2
formula: C3H5NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m1/s1
inchikey: XUJNEKJLAYXESH-UWTATZPHSA-L
mass: 119.14334
monoisotopicmass: 119.00520
smiles: N[C@H](C[S-])C([O-])=O
database_cross_reference: Gmelin:1342792
has exact synonym: D-cysteinate
has exact synonym: D-cysteinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-sulfidopropanoate
has_related_synonym: D-cysteine dianion
id: CHEBI:32450
in subset: 3 STAR

D-cysteinium
type: Class
subclass of: cysteinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-cysteine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-cysteine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-cysteinium
definition: The D-enantiomer of cysteinium.
imported from: chebi.owl
charge: +1
formula: C3H8NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m1/s1
inchikey: XUJNEKJLAYXESH-UWTATZPHSA-O
mass: 122.16716
monoisotopicmass: 122.02703
smiles: [NH3+][C@H](CS)C(O)=O
database_cross_reference: Gmelin:363237
has exact synonym: D-cysteinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-2-mercaptoethanaminium
has_related_synonym: (1S)-1-carboxy-2-sulfanylethanaminium
has_related_synonym: D-cysteine cation
id: CHEBI:32451
in subset: 3 STAR

cysteinate(1-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: CHEBI_63470
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cysteinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: cysteine
subclass of: Restriction
  on property: is conjugate base of
  some values from: cysteine zwitterion
definition: A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C3H6NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1
inchikey: XUJNEKJLAYXESH-UHFFFAOYSA-M
mass: 120.15128
monoisotopicmass: 120.01247
smiles: NC(CS)C([O-])=O
database_cross_reference: Beilstein:4128885
database_cross_reference: Gmelin:363235
database_cross_reference: Reaxys:4128885
has exact synonym: cysteinate(1-)
has exact synonym: hydrogen cysteinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-mercaptopropanoate
has_related_synonym: 2-amino-3-sulfanylpropanoate
has_related_synonym: cys(-)
has_related_synonym: cysteine monoanion
id: CHEBI:32456
in subset: 3 STAR

cysteinate(2-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: cysteinate(1-)
imported from: chebi.owl
charge: -2
formula: C3H5NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2
inchikey: XUJNEKJLAYXESH-UHFFFAOYSA-L
mass: 119.14334
monoisotopicmass: 119.00520
smiles: NC(C[S-])C([O-])=O
database_cross_reference: Gmelin:49990
has exact synonym: cysteinate
has exact synonym: cysteinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-sulfidopropanoate
has_related_synonym: cysteine dianion
id: CHEBI:32457
in subset: 3 STAR

cysteinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cysteine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cysteine zwitterion
imported from: chebi.owl
charge: +1
formula: C3H8NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1
inchikey: XUJNEKJLAYXESH-UHFFFAOYSA-O
mass: 122.16716
monoisotopicmass: 122.02703
smiles: [NH3+]C(CS)C(O)=O
database_cross_reference: Gmelin:325859
has exact synonym: 1-carboxy-2-sulfanylethanaminium
has exact synonym: cysteinium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-mercaptoethanaminium
has_related_synonym: H2cys(+)
has_related_synonym: cysteine cation
id: CHEBI:32458
in subset: 3 STAR

L-phenylalaninate
type: Class
subclass of: phenylalaninate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-phenylalanine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-phenylalaninate
definition: An optically active form of phenylalaninate having L-configuration.
imported from: chebi.owl
charge: -1
formula: C9H10NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m0/s1
inchikey: COLNVLDHVKWLRT-QMMMGPOBSA-M
mass: 164.18120
monoisotopicmass: 164.07170
smiles: N[C@@H](Cc1ccccc1)C([O-])=O
database_cross_reference: Beilstein:4136718
database_cross_reference: Gmelin:329084
database_cross_reference: PMID:21956539
database_cross_reference: Reaxys:4136718
has exact synonym: L-phenylalaninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-phenylpropanoate
has_related_synonym: L-phenylalanine anion
id: CHEBI:32486
in subset: 3 STAR

L-phenylalaninium
type: Class
subclass of: phenylalaninium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-phenylalanine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-phenylalaninium
definition: An optically active form of phenylalaninium having L-configuration.
imported from: chebi.owl
charge: +1
formula: C9H12NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m0/s1
inchikey: COLNVLDHVKWLRT-QMMMGPOBSA-O
mass: 166.19710
monoisotopicmass: 166.08626
smiles: [NH3+][C@@H](Cc1ccccc1)C(O)=O
database_cross_reference: PMID:21956539
has exact synonym: L-phenylalaninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-2-phenylethanaminium
has_related_synonym: L-phenylalanine cation
id: CHEBI:32487
in subset: 3 STAR

D-phenylalaninate
type: Class
subclass of: phenylalaninate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-phenylalanine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-phenylalaninate
definition: The D-enantiomer of phenylalaninate.
imported from: chebi.owl
charge: -1
formula: C9H10NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m1/s1
inchikey: COLNVLDHVKWLRT-MRVPVSSYSA-M
mass: 164.18120
monoisotopicmass: 164.07170
smiles: N[C@H](Cc1ccccc1)C([O-])=O
database_cross_reference: Beilstein:5740552
database_cross_reference: Gmelin:746993
has exact synonym: D-phenylalaninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-phenylpropanoate
has_related_synonym: D-phenylalanine anion
id: CHEBI:32494
in subset: 3 STAR

D-phenylalaninium
type: Class
subclass of: phenylalaninium
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-phenylalanine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-phenylalaninium
definition: An optically active form of phenylalaninium having D-configuration.
imported from: chebi.owl
charge: +1
formula: C9H12NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m1/s1
inchikey: COLNVLDHVKWLRT-MRVPVSSYSA-O
mass: 166.19710
monoisotopicmass: 166.08626
smiles: [NH3+][C@H](Cc1ccccc1)C(O)=O
has exact synonym: D-phenylalaninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-2-phenylethanaminium
has_related_synonym: D-phenylalanine cation
id: CHEBI:32495
in subset: 3 STAR

phenylalaninate
type: Class
subclass of: alpha-amino-acid anion
subclass of: CHEBI_63473
subclass of: Restriction
  on property: is conjugate base of
  some values from: phenylalanine
definition: An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C9H10NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1
inchikey: COLNVLDHVKWLRT-UHFFFAOYSA-M
mass: 164.18120
monoisotopicmass: 164.07170
smiles: NC(Cc1ccccc1)C([O-])=O
database_cross_reference: Gmelin:329083
has exact synonym: phenylalaninate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-phenylpropanoate
has_related_synonym: phenylalanine anion
id: CHEBI:32504
in subset: 3 STAR

phenylalaninium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: phenylalanine
definition: An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C9H12NO2
inchi: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1
inchikey: COLNVLDHVKWLRT-UHFFFAOYSA-O
mass: 166.19710
monoisotopicmass: 166.08626
smiles: [NH3+]C(Cc1ccccc1)C(O)=O
has exact synonym: phenylalaninium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-phenylethanaminium
has_related_synonym: phenylalanine cation
id: CHEBI:32505
in subset: 3 STAR

glycinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glycine
definition: An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino.
imported from: chebi.owl
charge: +1
formula: C2H6NO2
inchi: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p+1
inchikey: DHMQDGOQFOQNFH-UHFFFAOYSA-O
mass: 76.07458
monoisotopicmass: 76.03930
smiles: [NH3+]CC(O)=O
database_cross_reference: Gmelin:323509
has exact synonym: glycinium
has_obo_namespace: chebi_ontology
has_related_synonym: H2gly(+)
has_related_synonym: NH3(+)-CH2-COOH
has_related_synonym: carboxymethanaminium
has_related_synonym: glycine cation
id: CHEBI:32507
in subset: 3 STAR

glycinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: glycine
definition: An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C2H4NO2
inchi: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/p-1
inchikey: DHMQDGOQFOQNFH-UHFFFAOYSA-M
mass: 74.05870
monoisotopicmass: 74.02475
smiles: NCC([O-])=O
database_cross_reference: Beilstein:1852023
database_cross_reference: Gmelin:81890
database_cross_reference: Reaxys:1852023
database_cross_reference: UM-BBD_compID:c0559
has exact synonym: glycinate
has_obo_namespace: chebi_ontology
has_related_synonym: H2N-CH2-COO(-)
has_related_synonym: aminoacetate
has_related_synonym: gly(-)
has_related_synonym: glycine anion
id: CHEBI:32508
in subset: 3 STAR

histidinate(1-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: histidinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: histidine
imported from: chebi.owl
charge: -1
formula: C6H8N3O2
inchi: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/p-1
inchikey: HNDVDQJCIGZPNO-UHFFFAOYSA-M
mass: 154.14660
monoisotopicmass: 154.06220
smiles: NC(Cc1c[nH]cn1)C([O-])=O
database_cross_reference: Beilstein:3959092
database_cross_reference: Gmelin:364417
has exact synonym: histidinate(1-)
has exact synonym: hydrogen histidinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-(1H-imidazol-4-yl)propanoate
has_related_synonym: histidine anion
id: CHEBI:32529
in subset: 3 STAR

histidinate(2-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: histidinate(1-)
imported from: chebi.owl
charge: -2
formula: C6H7N3O2
inchi: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H2,8,9,10,11)/p-2
inchikey: TWRZMXZXJKNOLO-UHFFFAOYSA-L
mass: 153.13880
monoisotopicmass: 153.05492
smiles: NC(Cc1c[n-]cn1)C([O-])=O
has exact synonym: histidinate
has exact synonym: histidinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-imidazol-1-id-4-ylpropanoate
has_related_synonym: histidine dianion
id: CHEBI:32530
in subset: 3 STAR

histidinium(1+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: histidine
subclass of: Restriction
  on property: is conjugate base of
  some values from: histidinium(2+)
imported from: chebi.owl
charge: +1
formula: C6H10N3O2
inchi: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/p+1
inchikey: HNDVDQJCIGZPNO-UHFFFAOYSA-O
mass: 156.16262
monoisotopicmass: 156.07675
smiles: [NH3+]C(Cc1c[nH]c[nH+]1)C([O-])=O
has exact synonym: histidinium
has exact synonym: histidinium(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-ammonio-3-(1H-imidazol-3-ium-4-yl)propanoate
has_related_synonym: histidine monocation
id: CHEBI:32531
in subset: 3 STAR

histidinium(2+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: histidinium(1+)
imported from: chebi.owl
charge: +2
formula: C6H11N3O2
inchi: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/p+2
inchikey: HNDVDQJCIGZPNO-UHFFFAOYSA-P
mass: 157.17056
monoisotopicmass: 157.08403
smiles: [NH3+]C(Cc1c[nH]c[nH+]1)C(O)=O
database_cross_reference: Gmelin:1151904
has exact synonym: histidinediium
has exact synonym: histidinium(2+)
has_obo_namespace: chebi_ontology
has_related_synonym: 4-(2-ammonio-2-carboxyethyl)-1H-imidazol-3-ium
has_related_synonym: histidine dication
id: CHEBI:32532
in subset: 3 STAR

L-lysinate
type: Class
subclass of: lysinate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-lysine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysinate
definition: An optically active form of lysinate having L-configuration.
imported from: chebi.owl
charge: -1
formula: C6H13N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p-1/t5-/m0/s1
inchikey: KDXKERNSBIXSRK-YFKPBYRVSA-M
mass: 145.17970
monoisotopicmass: 145.09825
smiles: NCCCC[C@H](N)C([O-])=O
database_cross_reference: Beilstein:4383108
database_cross_reference: Gmelin:327969
database_cross_reference: Reaxys:4383108
has exact synonym: L-lysinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2,6-diaminohexanoate
has_related_synonym: L-lysinate(1-)
has_related_synonym: L-lysine anion
id: CHEBI:32550
in subset: 3 STAR

L-lysinium(1+)
type: Class
subclass of: lysinium(1+)
subclass of: CHEBI_62031
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-lysine zwitterion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-lysine
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-lysinium(2+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysinium(1+)
definition: An optically active form of lysinium having L-configuration.
imported from: chebi.owl
charge: +1
formula: C6H15N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m0/s1
inchikey: KDXKERNSBIXSRK-YFKPBYRVSA-O
mass: 147.19558
monoisotopicmass: 147.11280
smiles: [NH3+]CCCC[C@H]([NH3+])C([O-])=O
database_cross_reference: Gmelin:1149956
database_cross_reference: MetaCyc:LYS
has exact synonym: L-lysinium
has exact synonym: L-lysinium(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2,6-diammoniohexanoate
has_related_synonym: L-lysine
has_related_synonym: L-lysine monocation
id: CHEBI:32551
in subset: 3 STAR

L-lysinium(2+)
type: Class
subclass of: lysinium(2+)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-lysinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-lysinium(2+)
definition: The L-enantiomer of lysinium(2+).
imported from: chebi.owl
charge: +2
formula: C6H16N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+2/t5-/m0/s1
inchikey: KDXKERNSBIXSRK-YFKPBYRVSA-P
mass: 148.20352
monoisotopicmass: 148.12008
smiles: [NH3+]CCCC[C@H]([NH3+])C(O)=O
database_cross_reference: Gmelin:1068715
has exact synonym: L-lysinediium
has exact synonym: L-lysinium(2+)
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxypentane-1,5-diaminium
has_related_synonym: L-lysine dication
id: CHEBI:32552
in subset: 3 STAR

D-lysinate
type: Class
subclass of: lysinate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76946
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-lysine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysinate
definition: An optically active form of lysinate having D-configuration.
imported from: chebi.owl
charge: -1
formula: C6H13N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p-1/t5-/m1/s1
inchikey: KDXKERNSBIXSRK-RXMQYKEDSA-M
mass: 145.17970
monoisotopicmass: 145.09825
smiles: NCCCC[C@@H](N)C([O-])=O
database_cross_reference: Gmelin:1484324
has exact synonym: D-lysinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2,6-diaminohexanoate
has_related_synonym: D-lysinate(1-)
has_related_synonym: D-lysine anion
id: CHEBI:32556
in subset: 3 STAR

D-lysinium(1+)
type: Class
subclass of: lysinium(1+)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76946
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-lysine
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-lysinium(2+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysinium(1+)
definition: An optically active form of lysinium having D-configuration.
imported from: chebi.owl
charge: +1
formula: C6H15N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m1/s1
inchikey: KDXKERNSBIXSRK-RXMQYKEDSA-O
mass: 147.19558
monoisotopicmass: 147.11280
smiles: [NH3+]CCCC[C@@H]([NH3+])C([O-])=O
has exact synonym: D-lysinium
has exact synonym: D-lysinium(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2,6-diammoniohexanoate
has_related_synonym: D-lysine
has_related_synonym: D-lysine monocation
id: CHEBI:32557
in subset: 3 STAR

D-lysinium(2+)
type: Class
subclass of: lysinium(2+)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76946
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-lysinium(1+)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-lysinium(2+)
definition: The D-enantiomer of lysinium(2+).
imported from: chebi.owl
charge: +2
formula: C6H16N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+2/t5-/m1/s1
inchikey: KDXKERNSBIXSRK-RXMQYKEDSA-P
mass: 148.20352
monoisotopicmass: 148.12008
smiles: [NH3+]CCCC[C@@H]([NH3+])C(O)=O
has exact synonym: D-lysinediium
has exact synonym: D-lysinium(2+)
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxypentane-1,5-diaminium
has_related_synonym: D-lysine dication
id: CHEBI:32558
in subset: 3 STAR

lysinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: lysine
definition: An alpha-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C6H13N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p-1
inchikey: KDXKERNSBIXSRK-UHFFFAOYSA-M
mass: 145.17970
monoisotopicmass: 145.09825
smiles: NCCCCC(N)C([O-])=O
database_cross_reference: Gmelin:815095
has exact synonym: lysinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2,6-diaminohexanoate
has_related_synonym: lys(-)
has_related_synonym: lysinate(1-)
has_related_synonym: lysine anion
id: CHEBI:32563
in subset: 3 STAR

lysinium(1+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: lysine
subclass of: Restriction
  on property: is conjugate base of
  some values from: lysinium(2+)
definition: An alpha-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group.
imported from: chebi.owl
charge: +1
formula: C6H15N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1
inchikey: KDXKERNSBIXSRK-UHFFFAOYSA-O
mass: 147.19558
monoisotopicmass: 147.11280
smiles: [NH3+]CCCCC([NH3+])C([O-])=O
has exact synonym: lysinium
has exact synonym: lysinium(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: 2,6-diammoniohexanoate
has_related_synonym: lysine monocation
id: CHEBI:32564
in subset: 3 STAR

lysinium(2+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: lysinium(1+)
definition: An alpha-amino-acid cation obtained by protonation of both amino groups of lysine.
imported from: chebi.owl
charge: +2
formula: C6H16N2O2
inchi: InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+2
inchikey: KDXKERNSBIXSRK-UHFFFAOYSA-P
mass: 148.20352
monoisotopicmass: 148.12008
smiles: [NH3+]CCCCC([NH3+])C(O)=O
has exact synonym: lysinediium
has exact synonym: lysinium(2+)
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxypentane-1,5-diaminium
has_related_synonym: lysine dication
id: CHEBI:32565
in subset: 3 STAR

lysine residue
type: Class
subclass of: alpha-amino-acid residue
subclass of: Restriction
  on property: is conjugate base of
  some values from: lysinium residue
subclass of: Restriction
  on property: is substituent group from
  some values from: lysine
imported from: chebi.owl
charge: 0
formula: C6H12N2O
mass: 128.17236
monoisotopicmass: 128.09496
smiles: C(C(C(*)=O)N*)CCCN
has exact synonym: lysine residue
has_obo_namespace: chebi_ontology
has_related_synonym: lysine base residue
has_related_synonym: lysyl
id: CHEBI:32568
in subset: 3 STAR

lysinium residue
type: Class
subclass of: alpha-amino-acid residue cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: lysine residue
subclass of: Restriction
  on property: is substituent group from
  some values from: lysinium(1+)
imported from: chebi.owl
charge: +1
formula: C6H13N2O
mass: 129.18030
monoisotopicmass: 129.10279
smiles: C(C(C(*)=O)N*)CCC[NH3+]
has exact synonym: lysinium residue
has_obo_namespace: chebi_ontology
id: CHEBI:32579
in subset: 3 STAR

tetracene
type: Class
subclass of: acene
subclass of: CHEBI_51270
definition: An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement.
imported from: chebi.owl
charge: 0
formula: C18H12
inchi: InChI=1S/C18H12/c1-2-6-14-10-18-12-16-8-4-3-7-15(16)11-17(18)9-13(14)5-1/h1-12H
inchikey: IFLREYGFSNHWGE-UHFFFAOYSA-N
mass: 228.28788
monoisotopicmass: 228.09390
smiles: c1ccc2cc3cc4ccccc4cc3cc2c1
database_cross_reference: Beilstein:1909299
database_cross_reference: CAS:92-24-0
database_cross_reference: Gmelin:306993
database_cross_reference: PMID:11493061
database_cross_reference: PMID:24655187
database_cross_reference: Reaxys:1909299
database_cross_reference: Wikipedia:Tetracene
has exact synonym: tetracene
has_obo_namespace: chebi_ontology
has_related_synonym: 2,3-benzanthracene
has_related_synonym: benz[b]anthracene
has_related_synonym: naphthacene
id: CHEBI:32600
in subset: 3 STAR

isoleucinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: isoleucine
imported from: chebi.owl
database_cross_reference: Gmelin:101585
has exact synonym: isoleucinate
has_obo_namespace: chebi_ontology
has_related_synonym: ile(-)
has_related_synonym: isoleucine anion
has_related_synonym: rel-(2R,3R)-2-amino-3-methylpentanoate
id: CHEBI:32612
in subset: 3 STAR

isoleucinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: isoleucine
imported from: chebi.owl
database_cross_reference: Gmelin:1651827
has exact synonym: isoleucinium
has_obo_namespace: chebi_ontology
has_related_synonym: H2ile(+)
has_related_synonym: isoleucine cation
has_related_synonym: rel-(1R,2R)-1-carboxy-2-methylbutan-1-aminium
id: CHEBI:32613
in subset: 3 STAR

L-leucinate
type: Class
subclass of: leucinate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-leucine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-leucinate
definition: The L-enantiomer of leucinate.
imported from: chebi.owl
charge: -1
formula: C6H12NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p-1/t5-/m0/s1
inchikey: ROHFNLRQFUQHCH-YFKPBYRVSA-M
mass: 130.16502
monoisotopicmass: 130.08735
smiles: CC(C)C[C@H](N)C([O-])=O
database_cross_reference: Beilstein:3537983
database_cross_reference: Gmelin:326784
has exact synonym: L-leucinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-4-methylpentanoate
has_related_synonym: L-leucine anion
id: CHEBI:32619
in subset: 3 STAR

L-leucinium
type: Class
subclass of: leucinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-leucine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-leucinium
definition: The L-enantiomer of leucinium.
imported from: chebi.owl
charge: +1
formula: C6H14NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p+1/t5-/m0/s1
inchikey: ROHFNLRQFUQHCH-YFKPBYRVSA-O
mass: 132.18090
monoisotopicmass: 132.10191
smiles: CC(C)C[C@H]([NH3+])C(O)=O
has exact synonym: L-leucinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-3-methylbutan-1-aminium
has_related_synonym: L-leucine cation
id: CHEBI:32620
in subset: 3 STAR

D-leucinate
type: Class
subclass of: leucinate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-leucine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-leucinate
definition: The D-enantiomer of leucinate.
imported from: chebi.owl
charge: -1
formula: C6H12NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p-1/t5-/m1/s1
inchikey: ROHFNLRQFUQHCH-RXMQYKEDSA-M
mass: 130.16502
monoisotopicmass: 130.08735
smiles: CC(C)C[C@@H](N)C([O-])=O
database_cross_reference: Gmelin:533394
has exact synonym: D-leucinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-4-methylpentanoate
has_related_synonym: D-leucine anion
id: CHEBI:32623
in subset: 3 STAR

D-leucinium
type: Class
subclass of: leucinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-leucine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-leucinium
definition: The D-enantiomer of leucinium.
imported from: chebi.owl
charge: +1
formula: C6H14NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p+1/t5-/m1/s1
inchikey: ROHFNLRQFUQHCH-RXMQYKEDSA-O
mass: 132.18090
monoisotopicmass: 132.10191
smiles: CC(C)C[C@@H]([NH3+])C(O)=O
database_cross_reference: Gmelin:363610
has exact synonym: D-leucinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-3-methylbutan-1-aminium
has_related_synonym: D-leucine cation
id: CHEBI:32624
in subset: 3 STAR

leucinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: CHEBI_63471
subclass of: Restriction
  on property: is conjugate base of
  some values from: leucine
definition: An alpha-amino-acid anion that is the conjugate base of leucine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C6H12NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p-1
inchikey: ROHFNLRQFUQHCH-UHFFFAOYSA-M
mass: 130.16502
monoisotopicmass: 130.08735
smiles: CC(C)CC(N)C([O-])=O
database_cross_reference: Reaxys:5245805
has exact synonym: leucinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-4-methylpentanoate
has_related_synonym: leu(-)
has_related_synonym: leucine anion
id: CHEBI:32627
in subset: 3 STAR

leucinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: leucine
definition: An alpha-amino-acid cation that is the conjugate acid of leucine, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C6H14NO2
inchi: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/p+1
inchikey: ROHFNLRQFUQHCH-UHFFFAOYSA-O
mass: 132.18090
monoisotopicmass: 132.10191
smiles: CC(C)CC([NH3+])C(O)=O
database_cross_reference: Gmelin:1651836
has exact synonym: leucinium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-3-methylbutan-1-aminium
has_related_synonym: H2leu(+)
has_related_synonym: leucine cation
id: CHEBI:32628
in subset: 3 STAR

L-methioninate
type: Class
subclass of: methioninate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-methionine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-methioninate
definition: The L-enantiomer of methioninate.
imported from: chebi.owl
charge: -1
formula: C5H10NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p-1/t4-/m0/s1
inchikey: FFEARJCKVFRZRR-BYPYZUCNSA-M
mass: 148.20444
monoisotopicmass: 148.04377
smiles: CSCC[C@H](N)C([O-])=O
database_cross_reference: Beilstein:4740675
database_cross_reference: Gmelin:326566
database_cross_reference: Reaxys:4740675
has exact synonym: L-methioninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-4-(methylsulfanyl)butanoate
has_related_synonym: L-methionine anion
id: CHEBI:32631
in subset: 3 STAR

L-methioninium
type: Class
subclass of: methioninium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-methionine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-methioninium
definition: The L-enantiomer of methioninium.
imported from: chebi.owl
charge: +1
formula: C5H12NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p+1/t4-/m0/s1
inchikey: FFEARJCKVFRZRR-BYPYZUCNSA-O
mass: 150.22032
monoisotopicmass: 150.05833
smiles: CSCC[C@H]([NH3+])C(O)=O
database_cross_reference: Gmelin:1568767
has exact synonym: L-methioninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-3-(methylsulfanyl)propan-1-aminium
has_related_synonym: L-methionine cation
id: CHEBI:32632
in subset: 3 STAR

D-methioninate
type: Class
subclass of: methioninate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-methionine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-methioninate
definition: The D-enantiomer of methioninate.
imported from: chebi.owl
charge: -1
formula: C5H10NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p-1/t4-/m1/s1
inchikey: FFEARJCKVFRZRR-SCSAIBSYSA-M
mass: 148.20444
monoisotopicmass: 148.04377
smiles: CSCC[C@@H](N)C([O-])=O
database_cross_reference: Gmelin:720123
has exact synonym: D-methioninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-4-(methylsulfanyl)butanoate
has_related_synonym: D-methionine anion
id: CHEBI:32637
in subset: 3 STAR

D-methioninium
type: Class
subclass of: methioninium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-methionine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-methioninium
definition: The D-enantiomer of methioninium.
imported from: chebi.owl
charge: +1
formula: C5H12NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p+1/t4-/m1/s1
inchikey: FFEARJCKVFRZRR-SCSAIBSYSA-O
mass: 150.22032
monoisotopicmass: 150.05833
smiles: CSCC[C@@H]([NH3+])C(O)=O
has exact synonym: D-methioninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-3-(methylsulfanyl)propan-1-aminium
has_related_synonym: D-methionine cation
id: CHEBI:32638
in subset: 3 STAR

methioninate
type: Class
subclass of: alpha-amino-acid anion
subclass of: CHEBI_63470
subclass of: Restriction
  on property: is conjugate base of
  some values from: methionine
definition: A sulfur-containing amino-acid anion that is the conjugate base of methionine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C5H10NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p-1
inchikey: FFEARJCKVFRZRR-UHFFFAOYSA-M
mass: 148.20444
monoisotopicmass: 148.04377
smiles: CSCCC(N)C([O-])=O
database_cross_reference: Beilstein:3937270
database_cross_reference: Gmelin:326565
database_cross_reference: Reaxys:3937270
has exact synonym: methioninate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-4-(methylsulfanyl)butanoate
has_related_synonym: met(-)
has_related_synonym: methionine anion
id: CHEBI:32644
in subset: 3 STAR

methioninium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: methionine
definition: A sulfur-containing amino-acid anion that is the conjugate acid of methionine, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C5H12NO2S
inchi: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/p+1
inchikey: FFEARJCKVFRZRR-UHFFFAOYSA-O
mass: 150.22032
monoisotopicmass: 150.05833
smiles: CSCCC([NH3+])C(O)=O
database_cross_reference: Gmelin:326567
has exact synonym: methioninium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-3-(methylsulfanyl)propan-1-aminium
has_related_synonym: H2met(+)
has_related_synonym: methionine cation
id: CHEBI:32646
in subset: 3 STAR

L-asparaginate
type: Class
subclass of: asparaginate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-asparagine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-asparaginate
definition: An optically active form of asparaginate having L-configuration.
imported from: chebi.owl
charge: -1
formula: C4H7N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p-1/t2-/m0/s1
inchikey: DCXYFEDJOCDNAF-REOHCLBHSA-M
mass: 131.11006
monoisotopicmass: 131.04622
smiles: N[C@@H](CC(N)=O)C([O-])=O
database_cross_reference: Beilstein:6115348
database_cross_reference: Gmelin:327371
database_cross_reference: HMDB:HMDB0000168
database_cross_reference: Reaxys:6115348
has exact synonym: L-asparaginate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2,4-diamino-4-oxobutanoate
has_related_synonym: L-asparagine anion
id: CHEBI:32650
in subset: 3 STAR

L-asparaginium
type: Class
subclass of: asparaginium
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-asparagine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-asparaginium
imported from: chebi.owl
charge: +1
formula: C4H9N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p+1/t2-/m0/s1
inchikey: DCXYFEDJOCDNAF-REOHCLBHSA-O
mass: 133.12594
monoisotopicmass: 133.06077
smiles: NC(=O)C[C@H]([NH3+])C(O)=O
has exact synonym: L-asparaginium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-3-amino-1-carboxy-3-oxopropan-1-aminium
has_related_synonym: L-asparagine cation
id: CHEBI:32651
in subset: 3 STAR

D-asparaginate
type: Class
subclass of: asparaginate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-asparagine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-asparaginate
imported from: chebi.owl
charge: -1
formula: C4H7N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p-1/t2-/m1/s1
inchikey: DCXYFEDJOCDNAF-UWTATZPHSA-M
mass: 131.11006
monoisotopicmass: 131.04622
smiles: N[C@H](CC(N)=O)C([O-])=O
database_cross_reference: Gmelin:533547
has exact synonym: D-asparaginate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2,4-diamino-4-oxobutanoate
has_related_synonym: D-asparagine anion
id: CHEBI:32656
in subset: 3 STAR

D-asparaginium
type: Class
subclass of: asparaginium
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-asparagine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-asparaginium
imported from: chebi.owl
charge: +1
formula: C4H9N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p+1/t2-/m1/s1
inchikey: DCXYFEDJOCDNAF-UWTATZPHSA-O
mass: 133.12594
monoisotopicmass: 133.06077
smiles: NC(=O)C[C@@H]([NH3+])C(O)=O
has exact synonym: D-asparaginium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-3-amino-1-carboxy-3-oxopropan-1-aminium
has_related_synonym: D-asparagine cation
id: CHEBI:32657
in subset: 3 STAR

asparaginate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: asparagine
definition: An alpha-amino-acid anion that is the conjugate base of asparagine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C4H7N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p-1
inchikey: DCXYFEDJOCDNAF-UHFFFAOYSA-M
mass: 131.11006
monoisotopicmass: 131.04622
smiles: NC(CC(N)=O)C([O-])=O
database_cross_reference: Gmelin:327370
has exact synonym: asparaginate
has_obo_namespace: chebi_ontology
has_related_synonym: 2,4-diamino-4-oxobutanoate
has_related_synonym: asp(-)
has_related_synonym: asparagine anion
id: CHEBI:32660
in subset: 3 STAR

asparaginium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: asparagine
imported from: chebi.owl
charge: +1
formula: C4H9N2O3
inchi: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/p+1
inchikey: DCXYFEDJOCDNAF-UHFFFAOYSA-O
mass: 133.12594
monoisotopicmass: 133.06077
smiles: NC(=O)CC([NH3+])C(O)=O
has exact synonym: asparaginium
has_obo_namespace: chebi_ontology
has_related_synonym: 3-amino-1-carboxy-3-oxopropan-1-aminium
has_related_synonym: H2asp(+)
has_related_synonym: asparagine cation
id: CHEBI:32661
in subset: 3 STAR

glutaminate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: glutamine
definition: An alpha-amino-acid anion that is the conjugate base of glutamine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C5H9N2O3
inchi: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/p-1
inchikey: ZDXPYRJPNDTMRX-UHFFFAOYSA-M
mass: 145.13664
monoisotopicmass: 145.06187
smiles: NC(CCC(N)=O)C([O-])=O
database_cross_reference: Gmelin:464703
has exact synonym: glutaminate
has_obo_namespace: chebi_ontology
has_related_synonym: 2,5-diamino-5-oxopentanoate
has_related_synonym: gln(-)
has_related_synonym: glutamine anion
id: CHEBI:32678
in subset: 3 STAR

glutaminium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: glutamine
definition: An alpha-amino-acid cation that is the conjugate acid of glutamine, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C5H11N2O3
inchi: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/p+1
inchikey: ZDXPYRJPNDTMRX-UHFFFAOYSA-O
mass: 147.15252
monoisotopicmass: 147.07642
smiles: NC(=O)CCC([NH3+])C(O)=O
has exact synonym: glutaminium
has_obo_namespace: chebi_ontology
has_related_synonym: 4-amino-1-carboxy-4-oxobutan-1-aminium
has_related_synonym: H2gln(+)
has_related_synonym: glutamine cation
id: CHEBI:32679
in subset: 3 STAR

argininate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: arginine
imported from: chebi.owl
charge: -1
formula: C6H13N4O2
inchi: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p-1
inchikey: ODKSFYDXXFIFQN-UHFFFAOYSA-M
mass: 173.19318
monoisotopicmass: 173.10440
smiles: NC(CCCNC(N)=N)C([O-])=O
database_cross_reference: Gmelin:603497
has exact synonym: argininate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-5-(carbamimidamido)pentanoate
has_related_synonym: 2-amino-5-guanidinopentanoate
has_related_synonym: arg(-)
has_related_synonym: arginine anion
id: CHEBI:32695
in subset: 3 STAR

argininium(1+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: arginine
subclass of: Restriction
  on property: is conjugate base of
  some values from: argininium(2+)
imported from: chebi.owl
charge: +1
formula: C6H15N4O2
inchi: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1
inchikey: ODKSFYDXXFIFQN-UHFFFAOYSA-O
mass: 175.20906
monoisotopicmass: 175.11895
smiles: NC(=[NH2+])NCCCC([NH3+])C([O-])=O
database_cross_reference: Gmelin:1345599
has exact synonym: argininium
has exact synonym: argininium(1+)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-ammonio-5-guanidiniopentanoate
has_related_synonym: H2arg(+)
has_related_synonym: arginine
has_related_synonym: arginine monocation
id: CHEBI:32696
in subset: 3 STAR

argininium(2+)
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: argininium(1+)
imported from: chebi.owl
charge: +2
formula: C6H16N4O2
inchi: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+2
inchikey: ODKSFYDXXFIFQN-UHFFFAOYSA-P
mass: 176.21700
monoisotopicmass: 176.12623
smiles: NC(=[NH2+])NCCCC([NH3+])C(O)=O
has exact synonym: argininediium
has exact synonym: argininium(2+)
has_obo_namespace: chebi_ontology
has_related_synonym: (1-carboxy-4-guanidiniobutyl)ammonium
has_related_synonym: H3arg(2+)
has_related_synonym: arginine dication
id: CHEBI:32697
in subset: 3 STAR

tryptophanate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: tryptophan
definition: An alpha-amino-acid anion that is the conjugate base of tryptophan, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C11H11N2O2
inchi: InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/p-1
inchikey: QIVBCDIJIAJPQS-UHFFFAOYSA-M
mass: 203.21732
monoisotopicmass: 203.08260
smiles: NC(Cc1c[nH]c2ccccc12)C([O-])=O
database_cross_reference: Beilstein:4144997
database_cross_reference: Gmelin:331342
database_cross_reference: Reaxys:4144998
has exact synonym: tryptophanate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-(1H-indol-3-yl)propanoate
has_related_synonym: trp(-)
has_related_synonym: tryptophan anion
id: CHEBI:32727
in subset: 3 STAR

tryptophanium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tryptophan
definition: An alpha-amino-acid cation that is the conjugate acid of tryptophan, arising from protonation of the alpha-amino group.
imported from: chebi.owl
charge: +1
formula: C11H13N2O2
inchi: InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/p+1
inchikey: QIVBCDIJIAJPQS-UHFFFAOYSA-O
mass: 205.23320
monoisotopicmass: 205.09715
smiles: [NH3+]C(Cc1c[nH]c2ccccc12)C(O)=O
has exact synonym: tryptophanium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-(1H-indol-3-yl)ethanaminium
has_related_synonym: Htrp(+)
has_related_synonym: tryptophan cation
id: CHEBI:32728
in subset: 3 STAR

L-tyrosinate(1-)
type: Class
subclass of: tyrosinate(1-)
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-tyrosinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-tyrosine
subclass of: Restriction
  on property: is conjugate base of
  some values from: CHEBI_58315
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-tyrosinate(1-)
definition: An optically active form of tyrosinate having L-configuration.
imported from: chebi.owl
charge: -1
formula: C9H10NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-1/t8-/m0/s1
inchikey: OUYCCCASQSFEME-QMMMGPOBSA-M
mass: 180.18064
monoisotopicmass: 180.06662
smiles: N[C@@H](Cc1ccc(O)cc1)C([O-])=O
database_cross_reference: Beilstein:4784244
database_cross_reference: Gmelin:329373
database_cross_reference: Reaxys:4784244
has exact synonym: L-tyrosinate(1-)
has exact synonym: hydrogen L-tyrosinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-(4-hydroxyphenyl)propanoate
has_related_synonym: L-tyrosine anion
has_related_synonym: L-tyrosine monoanion
id: CHEBI:32760
in subset: 3 STAR

L-tyrosinate(2-)
type: Class
subclass of: tyrosinate(2-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-tyrosinate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-tyrosinate(2-)
definition: The L-enantiomer of tyrosinate(2-).
imported from: chebi.owl
charge: -2
formula: C9H9NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-2/t8-/m0/s1
inchikey: OUYCCCASQSFEME-QMMMGPOBSA-L
mass: 179.17270
monoisotopicmass: 179.05934
smiles: N[C@@H](Cc1ccc([O-])cc1)C([O-])=O
database_cross_reference: Beilstein:5339596
database_cross_reference: Gmelin:364975
database_cross_reference: Reaxys:5339596
has exact synonym: L-tyrosinate
has exact synonym: L-tyrosinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-(4-oxidophenyl)propanoate
has_related_synonym: L-tyrosine dianion
id: CHEBI:32761
in subset: 3 STAR

L-tyrosinium
type: Class
subclass of: tyrosinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-tyrosine
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_58315
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-tyrosinium
definition: An optically active form of tyrosinium having L-configuration.
imported from: chebi.owl
charge: +1
formula: C9H12NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p+1/t8-/m0/s1
inchikey: OUYCCCASQSFEME-QMMMGPOBSA-O
mass: 182.19652
monoisotopicmass: 182.08117
smiles: [NH3+][C@@H](Cc1ccc(O)cc1)C(O)=O
database_cross_reference: Gmelin:1150138
has exact synonym: L-tyrosinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-2-(4-hydroxyphenyl)ethanaminium
has_related_synonym: L-tyrosine cation
id: CHEBI:32762
in subset: 3 STAR

D-tyrosinate(1-)
type: Class
subclass of: tyrosinate(1-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-tyrosinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-tyrosine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-tyrosinate(1-)
definition: An optically active form of tyrosinate(1-) having D-configuration.
imported from: chebi.owl
charge: -1
formula: C9H10NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-1/t8-/m1/s1
inchikey: OUYCCCASQSFEME-MRVPVSSYSA-M
mass: 180.18064
monoisotopicmass: 180.06662
smiles: N[C@H](Cc1ccc(O)cc1)C([O-])=O
database_cross_reference: Gmelin:1484464
has exact synonym: D-tyrosinate(1-)
has exact synonym: hydrogen D-tyrosinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-(4-hydroxyphenyl)propanoate
has_related_synonym: D-tyrosine monoanion
id: CHEBI:32773
in subset: 3 STAR

D-tyrosinate(2-)
type: Class
subclass of: tyrosinate(2-)
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-tyrosinate(1-)
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-tyrosinate(2-)
definition: The D-enantiomer of tyrosinate(2-).
imported from: chebi.owl
charge: -2
formula: C9H9NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-2/t8-/m1/s1
inchikey: OUYCCCASQSFEME-MRVPVSSYSA-L
mass: 179.17270
monoisotopicmass: 179.05934
smiles: N[C@H](Cc1ccc([O-])cc1)C([O-])=O
has exact synonym: D-tyrosinate
has exact synonym: D-tyrosinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-(4-oxidophenyl)propanoate
has_related_synonym: D-tyrosine dianion
id: CHEBI:32774
in subset: 3 STAR

D-tyrosinium
type: Class
subclass of: tyrosinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-tyrosine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-tyrosinium
definition: An optically active form of tyrosinium having D-configuration.
imported from: chebi.owl
charge: +1
formula: C9H12NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p+1/t8-/m1/s1
inchikey: OUYCCCASQSFEME-MRVPVSSYSA-O
mass: 182.19652
monoisotopicmass: 182.08117
smiles: [NH3+][C@H](Cc1ccc(O)cc1)C(O)=O
database_cross_reference: Gmelin:364976
has exact synonym: D-tyrosinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-2-(4-hydroxyphenyl)ethanaminium
has_related_synonym: D-tyrosine cation
id: CHEBI:32775
in subset: 3 STAR

tyrosinate(1-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tyrosinate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: tyrosine
definition: An alpha-amino-acid anion that is the conjugate base of tyrosine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C9H10NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-1
inchikey: OUYCCCASQSFEME-UHFFFAOYSA-M
mass: 180.18064
monoisotopicmass: 180.06662
smiles: NC(Cc1ccc(O)cc1)C([O-])=O
database_cross_reference: Beilstein:3548387
database_cross_reference: Beilstein:4139515
database_cross_reference: Gmelin:329372
has exact synonym: hydrogen tyrosinate
has exact synonym: tyrosinate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-(4-hydroxyphenyl)propanoate
has_related_synonym: tyrosine anion
id: CHEBI:32784
in subset: 3 STAR

tyrosinate(2-)
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: tyrosinate(1-)
imported from: chebi.owl
charge: -2
formula: C9H9NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p-2
inchikey: OUYCCCASQSFEME-UHFFFAOYSA-L
mass: 179.17270
monoisotopicmass: 179.05934
smiles: NC(Cc1ccc([O-])cc1)C([O-])=O
has exact synonym: tyrosinate
has exact synonym: tyrosinate(2-)
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-(4-oxidophenyl)propanoate
has_related_synonym: tyrosine dianion
id: CHEBI:32785
in subset: 3 STAR

tyrosinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: tyrosine
definition: An alpha-amino-acid cation that is the conjugate acid of tyrosine, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C9H12NO3
inchi: InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/p+1
inchikey: OUYCCCASQSFEME-UHFFFAOYSA-O
mass: 182.19652
monoisotopicmass: 182.08117
smiles: [NH3+]C(Cc1ccc(O)cc1)C(O)=O
has exact synonym: tyrosinium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-(4-hydroxyphenyl)ethanaminium
has_related_synonym: tyrosine cation
id: CHEBI:32786
in subset: 3 STAR

L-threoninate
type: Class
subclass of: threoninate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-threonine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-threoninate
definition: An L-alpha-amino acid anion that is the conjugate base of L-threonine, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C4H8NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/p-1/t2-,3+/m1/s1
inchikey: AYFVYJQAPQTCCC-GBXIJSLDSA-M
mass: 118.11126
monoisotopicmass: 118.05097
smiles: C[C@@H](O)[C@H](N)C([O-])=O
database_cross_reference: Beilstein:4376295
database_cross_reference: Gmelin:464365
database_cross_reference: Reaxys:4376295
has exact synonym: L-threoninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S,3R)-2-amino-3-hydroxybutanoate
has_related_synonym: L-threonine anion
id: CHEBI:32820
in subset: 3 STAR

L-threoninium
type: Class
subclass of: threoninium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76971
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-threonine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-threoninium
definition: The L-enantiomer of threoninium.
imported from: chebi.owl
charge: +1
formula: C4H10NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/p+1/t2-,3+/m1/s1
inchikey: AYFVYJQAPQTCCC-GBXIJSLDSA-O
mass: 120.12714
monoisotopicmass: 120.06552
smiles: C[C@@H](O)[C@H]([NH3+])C(O)=O
has exact synonym: L-threoninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S,2R)-1-carboxy-2-hydroxypropan-1-aminium
has_related_synonym: L-threonine cation
id: CHEBI:32822
in subset: 3 STAR

D-threoninate
type: Class
subclass of: threoninate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-threonine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-threoninate
definition: The D-enantiomer of threoninate.
imported from: chebi.owl
charge: -1
formula: C4H8NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/p-1/t2-,3+/m0/s1
inchikey: AYFVYJQAPQTCCC-STHAYSLISA-M
mass: 118.11126
monoisotopicmass: 118.05097
smiles: C[C@H](O)[C@@H](N)C([O-])=O
database_cross_reference: Gmelin:1006174
has exact synonym: D-threoninate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R,3S)-2-amino-3-hydroxybutanoate
has_related_synonym: D-threonine anion
id: CHEBI:32827
in subset: 3 STAR

D-threoninium
type: Class
subclass of: threoninium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75772
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-threonine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-threoninium
definition: The D-enantiomer of threoninium.
imported from: chebi.owl
charge: +1
formula: C4H10NO3
inchi: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/p+1/t2-,3+/m0/s1
inchikey: AYFVYJQAPQTCCC-STHAYSLISA-O
mass: 120.12714
monoisotopicmass: 120.06552
smiles: C[C@H](O)[C@@H]([NH3+])C(O)=O
has exact synonym: D-threoninium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R,2S)-1-carboxy-2-hydroxypropan-1-aminium
has_related_synonym: D-threonine cation
id: CHEBI:32828
in subset: 3 STAR

threoninate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: threonine
imported from: chebi.owl
charge: 0
formula: C4H8NO3
mass: 118.111
monoisotopicmass: 118.05042
has exact synonym: threoninate
has_obo_namespace: chebi_ontology
has_related_synonym: rel-(2R,3S)-2-amino-3-hydroxybutanoate
has_related_synonym: threonine anion
id: CHEBI:32832
in subset: 3 STAR

threoninium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: threonine
imported from: chebi.owl
charge: 0
formula: C4H10NO3
mass: 120.127
monoisotopicmass: 120.06607
has exact synonym: threoninium
has_obo_namespace: chebi_ontology
has_related_synonym: rel-(1R,2S)-1-carboxy-2-hydroxypropan-1-aminium
has_related_synonym: threonine cation
id: CHEBI:32833
in subset: 3 STAR

L-serinate
type: Class
subclass of: serinate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-serine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-serinate
definition: A serinate that is the conjugate base of L-serine, obtained by deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C3H6NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p-1/t2-/m0/s1
inchikey: MTCFGRXMJLQNBG-REOHCLBHSA-M
mass: 104.08468
monoisotopicmass: 104.03532
smiles: N[C@@H](CO)C([O-])=O
database_cross_reference: Beilstein:4372751
database_cross_reference: Gmelin:324693
has exact synonym: L-serinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-hydroxypropanoate
has_related_synonym: L-serine anion
id: CHEBI:32836
in subset: 3 STAR

L-serinium
type: Class
subclass of: serinium
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-serine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-serinium
definition: A serinium that is the conjugate acid of L-serine, obtained by protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C3H8NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p+1/t2-/m0/s1
inchikey: MTCFGRXMJLQNBG-REOHCLBHSA-O
mass: 106.10056
monoisotopicmass: 106.04987
smiles: [NH3+][C@@H](CO)C(O)=O
has exact synonym: L-serinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-2-hydroxyethanaminium
has_related_synonym: L-serine cation
id: CHEBI:32837
in subset: 3 STAR

D-serinate
type: Class
subclass of: serinate
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-serine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-serinate
definition: The D-enantiomer of serinate.
imported from: chebi.owl
charge: -1
formula: C3H6NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p-1/t2-/m1/s1
inchikey: MTCFGRXMJLQNBG-UWTATZPHSA-M
mass: 104.08468
monoisotopicmass: 104.03532
smiles: N[C@H](CO)C([O-])=O
database_cross_reference: Gmelin:745975
has exact synonym: D-serinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-hydroxypropanoate
has_related_synonym: D-serine anion
id: CHEBI:32840
in subset: 3 STAR

D-serinium
type: Class
subclass of: serinium
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-serine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-serinium
definition: The D-enantiomer of serinium.
imported from: chebi.owl
charge: +1
formula: C3H8NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p+1/t2-/m1/s1
inchikey: MTCFGRXMJLQNBG-UWTATZPHSA-O
mass: 106.10056
monoisotopicmass: 106.04987
smiles: [NH3+][C@H](CO)C(O)=O
has exact synonym: D-serinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-2-hydroxyethanaminium
has_related_synonym: D-serine cation
id: CHEBI:32841
in subset: 3 STAR

serinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate base of
  some values from: serine
definition: An alpha-amino-acid anion that is the conjugate base of serine.
imported from: chebi.owl
charge: -1
formula: C3H6NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p-1
inchikey: MTCFGRXMJLQNBG-UHFFFAOYSA-M
mass: 104.08468
monoisotopicmass: 104.03532
smiles: NC(CO)C([O-])=O
database_cross_reference: Gmelin:324692
has exact synonym: serinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-hydroxypropanoate
has_related_synonym: serine anion
id: CHEBI:32845
in subset: 3 STAR

serinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: serine
definition: An alpha-amino-acid cation that is the conjugate acid of serine.
imported from: chebi.owl
charge: +1
formula: C3H8NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p+1
inchikey: MTCFGRXMJLQNBG-UHFFFAOYSA-O
mass: 106.10056
monoisotopicmass: 106.04987
smiles: [NH3+]C(CO)C(O)=O
database_cross_reference: Gmelin:1925675
has exact synonym: serinium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-hydroxyethanaminium
has_related_synonym: serine cation
id: CHEBI:32846
in subset: 3 STAR

L-valinate
type: Class
subclass of: valinate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-valine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-valinate
definition: The L-enantiomer of valinate.
imported from: chebi.owl
charge: -1
formula: C5H10NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p-1/t4-/m0/s1
inchikey: KZSNJWFQEVHDMF-BYPYZUCNSA-M
mass: 116.13844
monoisotopicmass: 116.07170
smiles: CC(C)[C@H](N)C([O-])=O
database_cross_reference: Beilstein:3933569
database_cross_reference: Gmelin:325409
has exact synonym: L-valinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-amino-3-methylbutanoate
has_related_synonym: L-valine anion
id: CHEBI:32851
in subset: 3 STAR

L-valinium
type: Class
subclass of: valinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-valine
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-valinium
definition: The L-enantiomer of valinium.
imported from: chebi.owl
charge: +1
formula: C5H12NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p+1/t4-/m0/s1
inchikey: KZSNJWFQEVHDMF-BYPYZUCNSA-O
mass: 118.15432
monoisotopicmass: 118.08626
smiles: CC(C)[C@H]([NH3+])C(O)=O
has exact synonym: L-valinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1S)-1-carboxy-2-methylpropan-1-aminium
has_related_synonym: L-valine cation
id: CHEBI:32852
in subset: 3 STAR

D-valinate
type: Class
subclass of: valinate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-valine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-valinate
definition: The D-enantiomer of valinate.
imported from: chebi.owl
charge: -1
formula: C5H10NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p-1/t4-/m1/s1
inchikey: KZSNJWFQEVHDMF-SCSAIBSYSA-M
mass: 116.13844
monoisotopicmass: 116.07170
smiles: CC(C)[C@@H](N)C([O-])=O
database_cross_reference: Gmelin:325408
has exact synonym: D-valinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-amino-3-methylbutanoate
has_related_synonym: D-valine anion
id: CHEBI:32855
in subset: 3 STAR

D-valinium
type: Class
subclass of: valinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76924
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-valine
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-valinium
definition: The D-enantiomer of valinium.
imported from: chebi.owl
charge: +1
formula: C5H12NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p+1/t4-/m1/s1
inchikey: KZSNJWFQEVHDMF-SCSAIBSYSA-O
mass: 118.15432
monoisotopicmass: 118.08626
smiles: CC(C)[C@@H]([NH3+])C(O)=O
has exact synonym: D-valinium
has_obo_namespace: chebi_ontology
has_related_synonym: (1R)-1-carboxy-2-methylpropan-1-aminium
has_related_synonym: D-valine cation
id: CHEBI:32856
in subset: 3 STAR

valinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: CHEBI_63471
subclass of: Restriction
  on property: is conjugate base of
  some values from: valine
imported from: chebi.owl
charge: -1
formula: C5H10NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p-1
inchikey: KZSNJWFQEVHDMF-UHFFFAOYSA-M
mass: 116.13844
monoisotopicmass: 116.07170
smiles: CC(C)C(N)C([O-])=O
database_cross_reference: Gmelin:49876
has exact synonym: valinate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-amino-3-methylbutanoate
has_related_synonym: val(-)
has_related_synonym: valine anion
id: CHEBI:32859
in subset: 3 STAR

valinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: valine
imported from: chebi.owl
charge: +1
formula: C5H12NO2
inchi: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/p+1
inchikey: KZSNJWFQEVHDMF-UHFFFAOYSA-O
mass: 118.15432
monoisotopicmass: 118.08626
smiles: CC(C)C([NH3+])C(O)=O
database_cross_reference: Gmelin:1651060
has exact synonym: valinium
has_obo_namespace: chebi_ontology
has_related_synonym: 1-carboxy-2-methylpropan-1-aminium
has_related_synonym: H2val(+)
has_related_synonym: valine cation
id: CHEBI:32860
in subset: 3 STAR

L-prolinate
type: Class
subclass of: prolinate
subclass of: CHEBI_59814
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-proline
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-prolinate
definition: An optically active form of prolinate having L-configuration.
imported from: chebi.owl
charge: -1
formula: C5H8NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1/t4-/m0/s1
inchikey: ONIBWKKTOPOVIA-BYPYZUCNSA-M
mass: 114.12250
monoisotopicmass: 114.05605
smiles: [O-]C(=O)[C@@H]1CCCN1
database_cross_reference: Beilstein:4307988
database_cross_reference: Gmelin:82610
database_cross_reference: Reaxys:4307988
has exact synonym: L-prolinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-pyrrolidine-2-carboxylate
has_related_synonym: L-proline anion
id: CHEBI:32862
in subset: 3 STAR

L-prolinium
type: Class
subclass of: prolinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-proline
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-prolinium
definition: An optically active form of prolinium having L-configuration.
imported from: chebi.owl
charge: +1
formula: C5H10NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1/t4-/m0/s1
inchikey: ONIBWKKTOPOVIA-BYPYZUCNSA-O
mass: 116.13840
monoisotopicmass: 116.07060
smiles: OC(=O)[C@@H]1CCC[NH2+]1
database_cross_reference: Gmelin:363493
has exact synonym: L-prolinium
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-carboxypyrrolidinium
has_related_synonym: L-proline cation
id: CHEBI:32864
in subset: 3 STAR

L-prolino group
type: Class
subclass of: prolino group
subclass of: C-terminal proteinogenic amino-acid residue
subclass of: CHEBI_83228
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-prolino group
subclass of: Restriction
  on property: is substituent group from
  some values from: L-proline
imported from: chebi.owl
charge: 0
formula: C5H8NO2
mass: 114.12250
monoisotopicmass: 114.05550
smiles: O=C(O)[C@@H]1CCCN1*
has exact synonym: (2S)-2-carboxypyrrolidin-1-yl
has_obo_namespace: chebi_ontology
has_related_synonym: -Pro
has_related_synonym: L-prolino
id: CHEBI:32866
in subset: 3 STAR

D-prolinate
type: Class
subclass of: prolinate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-proline
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-prolinate
definition: An optically active form of prolinate having D-configuration.
imported from: chebi.owl
charge: -1
formula: C5H8NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1/t4-/m1/s1
inchikey: ONIBWKKTOPOVIA-SCSAIBSYSA-M
mass: 114.12250
monoisotopicmass: 114.05605
smiles: [O-]C(=O)[C@H]1CCCN1
database_cross_reference: Gmelin:533350
has exact synonym: D-prolinate
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-pyrrolidine-2-carboxylate
has_related_synonym: D-proline anion
id: CHEBI:32867
in subset: 3 STAR

D-prolinium
type: Class
subclass of: prolinium
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-proline
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-prolinium
definition: An optically active form of prolinium having D-configuration.
imported from: chebi.owl
charge: +1
formula: C5H10NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1/t4-/m1/s1
inchikey: ONIBWKKTOPOVIA-SCSAIBSYSA-O
mass: 116.13840
monoisotopicmass: 116.07060
smiles: OC(=O)[C@H]1CCC[NH2+]1
database_cross_reference: Gmelin:363492
has exact synonym: D-prolinium
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-carboxypyrrolidinium
has_related_synonym: D-proline cation
id: CHEBI:32868
in subset: 3 STAR

D-prolino group
type: Class
subclass of: prolino group
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-prolino group
subclass of: Restriction
  on property: is substituent group from
  some values from: D-proline
imported from: chebi.owl
charge: 0
formula: C5H8NO2
mass: 114.12250
monoisotopicmass: 114.05550
smiles: O=C(O)[C@H]1CCCN1*
has exact synonym: (2R)-2-carboxypyrrolidin-1-yl
has_obo_namespace: chebi_ontology
has_related_synonym: -D-Pro
has_related_synonym: D-prolino
id: CHEBI:32870
in subset: 3 STAR

prolinate
type: Class
subclass of: alpha-amino-acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: proline
definition: An alpha-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group.
imported from: chebi.owl
charge: -1
formula: C5H8NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1
inchikey: ONIBWKKTOPOVIA-UHFFFAOYSA-M
mass: 114.12256
monoisotopicmass: 114.05605
smiles: [O-]C(=O)C1CCCN1
database_cross_reference: Beilstein:5387795
database_cross_reference: Gmelin:50151
database_cross_reference: Reaxys:5387795
has exact synonym: prolinate
has_obo_namespace: chebi_ontology
has_related_synonym: pro(-)
has_related_synonym: proline anion
has_related_synonym: pyrrolidine-2-carboxylate
id: CHEBI:32871
in subset: 3 STAR

prolinium
type: Class
subclass of: alpha-amino-acid cation
subclass of: Restriction
  on property: is conjugate acid of
  some values from: proline
definition: An alpha-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group.
imported from: chebi.owl
charge: +1
formula: C5H10NO2
inchi: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1
inchikey: ONIBWKKTOPOVIA-UHFFFAOYSA-O
mass: 116.13840
monoisotopicmass: 116.07060
smiles: OC(=O)C1CCC[NH2+]1
has exact synonym: prolinium
has_obo_namespace: chebi_ontology
has_related_synonym: 2-carboxypyrrolidinium
has_related_synonym: H2pro(+)
has_related_synonym: proline cation
id: CHEBI:32872
in subset: 3 STAR

prolino group
type: Class
subclass of: group
subclass of: Restriction
  on property: is substituent group from
  some values from: proline
imported from: chebi.owl
charge: 0
formula: C5H8NO2
mass: 114.12256
monoisotopicmass: 114.05550
smiles: O=C(O)C1CCCN1*
has exact synonym: 2-carboxypyrrolidin-1-yl
has_obo_namespace: chebi_ontology
has_related_synonym: prolino
id: CHEBI:32873
in subset: 3 STAR

tertiary amine
type: Class
subclass of: amine
subclass of: CHEBI_50996
definition: A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: NR3
mass: 14.00670
monoisotopicmass: 14.00307
smiles: [*]N([*])[*]
has_alternative_id: CHEBI:26879
has_alternative_id: CHEBI:9458
database_cross_reference: KEGG COMPOUND:C02196
database_cross_reference: KEGG:C02196
has exact synonym: Tertiary amine
has exact synonym: tertiary amines
has_obo_namespace: chebi_ontology
has_related_synonym: NR3
has_related_synonym: R3N
has_related_synonym: [*]N([*])[*]
has_related_synonym: tertiaeres Amin
id: CHEBI:32876
in subset: 3 STAR

primary amine
type: Class
subclass of: amine
subclass of: CHEBI_50994
definition: A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group.
imported from: chebi.owl
charge: 0
formula: H2NR
mass: 16.02260
monoisotopicmass: 16.01872
smiles: N[*]
has_alternative_id: CHEBI:26263
has_alternative_id: CHEBI:26265
has_alternative_id: CHEBI:8407
has_alternative_id: CHEBI:8409
database_cross_reference: KEGG:C00375
database_cross_reference: KEGG:C00893
database_cross_reference: KEGG:C02580
has exact synonym: Primary amine
has exact synonym: primary amines
has_obo_namespace: chebi_ontology
has_related_synonym: Primary monoamine
has_related_synonym: R-NH2
has_related_synonym: RCH2NH2
has_related_synonym: primaeres Amin
id: CHEBI:32877
in subset: 3 STAR

alkene
type: Class
subclass of: acyclic olefin
definition: An acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. Acyclic branched or unbranched hydrocarbons having more than one double bond are alkadienes, alkatrienes, etc.
imported from: chebi.owl
charge: 0
formula: C2H2R2
mass: 26.037
monoisotopicmass: 26.01565
has_alternative_id: CHEBI:22320
has_alternative_id: CHEBI:2581
database_cross_reference: KEGG:C01372
has exact synonym: Alkene
has_obo_namespace: chebi_ontology
has_related_synonym: alkenes
has_related_synonym: olefin
id: CHEBI:32878
in subset: 3 STAR

propane
type: Class
subclass of: gas molecular entity
subclass of: alkane
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78017
imported from: chebi.owl
charge: 0
formula: C3H8
inchi: InChI=1S/C3H8/c1-3-2/h3H2,1-2H3
inchikey: ATUOYWHBWRKTHZ-UHFFFAOYSA-N
mass: 44.09562
monoisotopicmass: 44.06260
smiles: CCC
database_cross_reference: Beilstein:1730718
database_cross_reference: CAS:74-98-6
database_cross_reference: Gmelin:25044
has exact synonym: propane
has_obo_namespace: chebi_ontology
has_related_synonym: CH3-CH2-CH3
has_related_synonym: E944
has_related_synonym: Propan
id: CHEBI:32879
in subset: 3 STAR

Cetylpyridinium
type: Class
subclass of: CHEBI_50334
has_RxCUI: 2286
definition: A pyridinium ion that has formula C21H38N.
imported from: chebi.owl
imported from: dron.owl
charge: +1
formula: C21H38N
inchikey: NEUSVAOJNUQRTM-UHFFFAOYSA-N
mass: 304.53316
monoisotopicmass: 304.29988
smiles: CCCCCCCCCCCCCCCC[n+]1ccccc1
database_cross_reference: Beilstein:1431415
database_cross_reference: CAS:7773-52-6
database_cross_reference: ChemIDplus:1431415
database_cross_reference: ChemIDplus:7773-52-6
database_cross_reference: Drug_Central:3083
database_cross_reference: Gmelin:342398
has exact synonym: 1-hexadecylpyridinium
has_obo_namespace: chebi_ontology
has_related_synonym: C21H38N
has_related_synonym: CCCCCCCCCCCCCCCC[n+]1ccccc1
has_related_synonym: InChIKey=NEUSVAOJNUQRTM-UHFFFAOYSA-N
has_related_synonym: N-hexadecylpyridinium
id: CHEBI:32914
in subset: 3 STAR
label: cetylpyridinium

cetylpyridinium chloride
type: Class
subclass of: chloride salt
subclass of: CHEBI_36094
subclass of: Restriction
  on property: has part
  some values from: Cetylpyridinium
subclass of: Restriction
  on property: chemical effective in vitro against virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: surfactant
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48218
definition: A pyridinium salt that has N-hexadecylpyridinium as the cation and chloride as the anion. It has antiseptic properties and is used in solutions or lozenges for the treatment of minor infections of the mouth and throat.
definition source: PMID: 30918074
imported from: chebi.owl
charge: 0
formula: C21H38ClN
inchikey: YMKDRGPMQRFJGP-UHFFFAOYSA-M
mass: 339.98600
monoisotopicmass: 339.26928
smiles: [Cl-].CCCCCCCCCCCCCCCC[n+]1ccccc1
database_cross_reference: Beilstein:3578606
database_cross_reference: CAS:123-03-5
database_cross_reference: Gmelin:33016
database_cross_reference: Wikipedia:Cetylpyridinium_Chloride
has exact synonym: 1-hexadecylpyridinium chloride
has_obo_namespace: chebi_ontology
has_related_synonym: 1-cetylpyridinium chloride
has_related_synonym: 1-palmitylpyridinium chloride
has_related_synonym: N-cetylpyridinium chloride
has_related_synonym: N-hexadecylpyridinium chloride
has_related_synonym: cetylpyridinii chloridum
has_related_synonym: cetylpyridinium chloride
has_related_synonym: cetylpyridinium chloride anhydrous
has_related_synonym: chlorure de cetylpyridinium
has_related_synonym: cloruro de cetilpiridinio
has_related_synonym: hexadecylpyridinium chloride
id: CHEBI:32915
in subset: 3 STAR

amine
type: Class
subclass of: CHEBI_50047
definition: A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:13814
has_alternative_id: CHEBI:22474
has_alternative_id: CHEBI:2641
database_cross_reference: KEGG COMPOUND:C00706
database_cross_reference: KEGG:C00706
has exact synonym: Amine
has exact synonym: amines
has_obo_namespace: chebi_ontology
has_related_synonym: Amin
has_related_synonym: Substituted amine
has_related_synonym: an amine
id: CHEBI:32952
in subset: 3 STAR

epoxide
type: Class
subclass of: CHEBI_37407
subclass of: Restriction
  on property: has parent hydride
  some values from: oxirane
definition: Any cyclic ether in which the oxygen atom forms part of a 3-membered ring.
imported from: chebi.owl
charge: 0
formula: C2OR4
mass: 40.02080
monoisotopicmass: 39.99491
smiles: [*]C1([*])OC1([*])[*]
has_alternative_id: CHEBI:13828
has_alternative_id: CHEBI:23930
has_alternative_id: CHEBI:4812
database_cross_reference: KEGG:C00722
database_cross_reference: PMID:10891060
database_cross_reference: Wikipedia:Epoxide
has exact synonym: Epoxide
has exact synonym: epoxides
has_obo_namespace: chebi_ontology
has_related_synonym: Alkene oxide
has_related_synonym: Olefin oxide
has_related_synonym: an epoxide
has_related_synonym: epoxides
id: CHEBI:32955
in subset: 3 STAR

amide
type: Class
subclass of: CHEBI_51143
definition: An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:22473
has_alternative_id: CHEBI:2633
database_cross_reference: KEGG COMPOUND:C00241
database_cross_reference: KEGG:C00241
has exact synonym: Amide
has exact synonym: amides
has_obo_namespace: chebi_ontology
id: CHEBI:32988
in subset: 3 STAR

vitamin (role)
type: Class
subclass of: micronutrient
subclass of: CHEBI_52206
definition: A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines.
imported from: chebi.owl
has_alternative_id: CHEBI:10004
has_alternative_id: CHEBI:27305
database_cross_reference: Wikipedia:Vitamin
has_obo_namespace: chebi_ontology
has_related_synonym: vitamin
has_related_synonym: vitamina
has_related_synonym: vitaminas
has_related_synonym: vitamine
has_related_synonym: vitamines
has_related_synonym: vitamins
has_related_synonym: vitaminum
id: CHEBI:33229
in subset: 3 STAR

application
type: Class
subclass of: CHEBI_50906
definition: Intended use of the molecular entity or part thereof by humans.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33232
in subset: 3 STAR

fundamental particle
type: Class
subclass of: CHEBI_36342
definition: A particle not known to have substructure.
imported from: chebi.owl
has exact synonym: elementary particle
has_obo_namespace: chebi_ontology
has_related_synonym: elementary particles
id: CHEBI:33233
in subset: 3 STAR

monoatomic entity
type: Class
subclass of: elemental molecular entity
definition: A monoatomic entity is a molecular entity consisting of a single atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: atomic entity
has_related_synonym: monoatomic entities
id: CHEBI:33238
in subset: 3 STAR

oxoacid derivative
type: Class
subclass of: CHEBI_37577
subclass of: Restriction
  on property: has functional parent
  some values from: oxoacid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacid derivatives
id: CHEBI:33241
in subset: 3 STAR

inorganic hydride
type: Class
subclass of: inorganic molecular entity
subclass of: hydrides
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic hydrides
id: CHEBI:33242
in subset: 3 STAR

organic fundamental parent
type: Class
subclass of: CHEBI_37175
subclass of: CHEBI_50860
definition: An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic fundamental parents
has_related_synonym: organic parent hydrides
id: CHEBI:33245
in subset: 3 STAR

inorganic group
type: Class
subclass of: group
definition: Any substituent group which does not contain carbon.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: inorganic groups
id: CHEBI:33246
in subset: 3 STAR

organic group
type: Class
subclass of: group
subclass of: Restriction
  on property: is substituent group from
  some values from: CHEBI_50860
definition: Any substituent group or skeleton containing carbon.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic groups
id: CHEBI:33247
in subset: 3 STAR

hydrocarbyl group
type: Class
subclass of: organyl group
subclass of: Restriction
  on property: is substituent group from
  some values from: hydrocarbon
definition: A univalent group formed by removing a hydrogen atom from a hydrocarbon.
imported from: chebi.owl
has exact synonym: hydrocarbyl group
has exact synonym: hydrocarbyl groups
has_obo_namespace: chebi_ontology
has_related_synonym: groupe hydrocarbyle
has_related_synonym: grupo hidrocarbilo
has_related_synonym: grupos hidrocarbilo
id: CHEBI:33248
in subset: 3 STAR

organyl group
type: Class
subclass of: CHEBI_51447
definition: Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
imported from: chebi.owl
has exact synonym: organyl group
has exact synonym: organyl groups
has_obo_namespace: chebi_ontology
has_related_synonym: groupe organyle
has_related_synonym: grupo organilo
has_related_synonym: grupos organilo
id: CHEBI:33249
in subset: 3 STAR

atom
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has part
  some values from: electron
subclass of: Restriction
  on property: has part
  some values from: atomic nucleus
definition: A chemical entity constituting the smallest component of an element having the chemical properties of the element.
imported from: chebi.owl
has_alternative_id: CHEBI:22671
has_alternative_id: CHEBI:23907
has exact synonym: atom
has_obo_namespace: chebi_ontology
has_related_synonym: atome
has_related_synonym: atomo
has_related_synonym: atoms
has_related_synonym: atomus
has_related_synonym: element
has_related_synonym: elements
id: CHEBI:33250
in subset: 3 STAR

atomic nucleus
type: Class
subclass of: CHEBI_36347
subclass of: Restriction
  on property: has part
  some values from: nucleon
definition: A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
imported from: chebi.owl
has exact synonym: nucleus
has_obo_namespace: chebi_ontology
has_related_synonym: Atomkern
has_related_synonym: Kern
has_related_synonym: noyau
has_related_synonym: noyau atomique
has_related_synonym: nuclei
has_related_synonym: nucleo
has_related_synonym: nucleo atomico
has_related_synonym: nucleus atomi
id: CHEBI:33252
in subset: 3 STAR

nucleon
type: Class
subclass of: CHEBI_36339
subclass of: CHEBI_36347
definition: Heavy nuclear particle: proton or neutron.
imported from: chebi.owl
has exact synonym: nucleon
has_obo_namespace: chebi_ontology
has_related_synonym: Nukleon
has_related_synonym: Nukleonen
has_related_synonym: nucleons
id: CHEBI:33253
in subset: 3 STAR

primary amide
type: Class
subclass of: amide
definition: A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: primary amide
has exact synonym: primary amides
has_obo_namespace: chebi_ontology
id: CHEBI:33256
in subset: 3 STAR

secondary amide
type: Class
subclass of: amide
definition: A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group.
imported from: chebi.owl
has exact synonym: secondary amide
has exact synonym: secondary amides
has_obo_namespace: chebi_ontology
id: CHEBI:33257
in subset: 3 STAR

elemental molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity all atoms of which have the same atomic number.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: homoatomic entity
has_related_synonym: homoatomic molecular entities
has_related_synonym: homoatomic molecular entity
id: CHEBI:33259
in subset: 3 STAR

organosulfur compound
type: Class
subclass of: sulfur molecular entity
subclass of: CHEBI_36962
definition: An organosulfur compound is a compound containing at least one carbon-sulfur bond.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:23010
has_alternative_id: CHEBI:25714
database_cross_reference: Wikipedia:Organosulfur_compounds
has exact synonym: organosulfur compound
has_obo_namespace: chebi_ontology
has_related_synonym: organosulfur compounds
id: CHEBI:33261
in subset: 3 STAR

diatomic nitrogen
type: Class
subclass of: elemental nitrogen
imported from: chebi.owl
charge: 0
formula: N2
mass: 28.013
monoisotopicmass: 28.00615
has_obo_namespace: chebi_ontology
id: CHEBI:33266
in subset: 3 STAR

elemental nitrogen
type: Class
subclass of: elemental pnictogen
subclass of: CHEBI_51143
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33267
in subset: 3 STAR

polyatomic anion
type: Class
subclass of: anion
subclass of: CHEBI_36358
definition: An anion consisting of more than one atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic anions
id: CHEBI:33273
in subset: 3 STAR

molecular messenger
type: Class
subclass of: biological role
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: chemical messenger
id: CHEBI:33280
in subset: 3 STAR

antimicrobial agent
type: Class
subclass of: biological role
definition: A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
imported from: chebi.owl
has_alternative_id: CHEBI:22582
database_cross_reference: PMID:12964249
database_cross_reference: PMID:22117953
database_cross_reference: PMID:22439833
database_cross_reference: PMID:22849268
database_cross_reference: PMID:22849276
database_cross_reference: PMID:22958833
has_obo_namespace: chebi_ontology
has_related_synonym: Antibiotika
has_related_synonym: Antibiotikum
has_related_synonym: antibiotic
has_related_synonym: antibiotics
has_related_synonym: antibiotique
has_related_synonym: antimicrobial
has_related_synonym: antimicrobial agents
has_related_synonym: antimicrobials
has_related_synonym: microbicide
has_related_synonym: microbicides
id: CHEBI:33281
in subset: 3 STAR

antibacterial agent
type: Class
subclass of: antimicrobial agent
definition: A substance (or active part thereof) that kills or slows the growth of bacteria.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antibacterial agents
has_related_synonym: antibacterials
has_related_synonym: bactericide
has_related_synonym: bactericides
id: CHEBI:33282
in subset: 3 STAR

nutrient
type: Class
subclass of: CHEBI_78295
definition: A nutrient is a food component that an organism uses to survive and grow.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: nutrients
id: CHEBI:33284
in subset: 3 STAR

heteroorganic entity
type: Class
subclass of: CHEBI_50860
definition: A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: heteroorganic entities
has_related_synonym: organoelement compounds
id: CHEBI:33285
in subset: 3 STAR

agrochemical
type: Class
subclass of: application
definition: An agrochemical is a substance that is used in agriculture or horticulture.
imported from: chebi.owl
database_cross_reference: Wikipedia:Agrochemical
has_obo_namespace: chebi_ontology
has_related_synonym: agrichemical
has_related_synonym: agrichemicals
has_related_synonym: agricultural chemicals
has_related_synonym: agrochemicals
id: CHEBI:33286
in subset: 3 STAR

fertilizer
type: Class
subclass of: agrochemical
definition: A fertilizer is any substance that is added to soil or water to assist the growth of plants.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: fertiliser
has_related_synonym: fertilizers
id: CHEBI:33287
in subset: 3 STAR

fuel
type: Class
subclass of: application
definition: An energy-rich substance that can be transformed with release of usable energy.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33292
in subset: 3 STAR

diagnostic agent
type: Class
subclass of: CHEBI_52217
definition: A substance administered to aid diagnosis of a disease.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: diagnostic aid
id: CHEBI:33295
in subset: 3 STAR

pnictogen
type: Class
subclass of: p-block element atom
definition: Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
imported from: chebi.owl
has exact synonym: pnictogens
has_obo_namespace: chebi_ontology
has_related_synonym: group 15 elements
has_related_synonym: group V elements
has_related_synonym: nitrogenoideos
has_related_synonym: nitrogenoides
has_related_synonym: pnictogene
has_related_synonym: pnictogenes
id: CHEBI:33300
in subset: 3 STAR

pnictogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: pnictogen
definition: A p-block molecular entity containing any pnictogen.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: pnictogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen molecular entities
id: CHEBI:33302
in subset: 3 STAR

chalcogen
type: Class
subclass of: p-block element atom
definition: Any p-block element belonging to the group 16 family of the periodic table.
imported from: chebi.owl
database_cross_reference: PMID:17084588
has exact synonym: chalcogen
has exact synonym: chalcogens
has_obo_namespace: chebi_ontology
has_related_synonym: Chalkogen
has_related_synonym: Chalkogene
has_related_synonym: anfigeno
has_related_synonym: anfigenos
has_related_synonym: calcogeno
has_related_synonym: calcogenos
has_related_synonym: chalcogene
has_related_synonym: chalcogenes
has_related_synonym: group 16 elements
has_related_synonym: group VI elements
id: CHEBI:33303
in subset: 3 STAR

chalcogen molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: chalcogen
definition: Any p-block molecular entity containing a chalcogen.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: chalcogen molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen compounds
has_related_synonym: chalcogen molecular entities
id: CHEBI:33304
in subset: 3 STAR

carbon group element atom
type: Class
subclass of: p-block element atom
imported from: chebi.owl
has exact synonym: group 14 elements
has_obo_namespace: chebi_ontology
has_related_synonym: carbon group element
has_related_synonym: carbon group elements
has_related_synonym: carbonoides
has_related_synonym: cristallogene
has_related_synonym: cristallogenes
has_related_synonym: group IV elements
id: CHEBI:33306
in subset: 3 STAR

carboxylic ester
type: Class
subclass of: ester
subclass of: CHEBI_36586
definition: An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.
definition: An ester of a carboxylic acid.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: CO2R2
mass: 44.010
monoisotopicmass: 43.98983
smiles: [*]C(=O)O[*]
has_alternative_id: CHEBI:13204
has_alternative_id: CHEBI:23028
has_alternative_id: CHEBI:3408
database_cross_reference: KEGG COMPOUND:C02391
database_cross_reference: KEGG:C02391
database_cross_reference: Wikipedia:Ester
has exact synonym: Carboxylic ester
has exact synonym: carboxylic ester
has exact synonym: carboxylic esters
has_obo_namespace: chebi_ontology
has_related_synonym: CO2R2
has_related_synonym: a carboxylic ester
has_related_synonym: carboxylic acid esters
id: CHEBI:33308
in subset: 3 STAR

main group element atom
type: Class
subclass of: atom
definition: An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
imported from: chebi.owl
has exact synonym: main group elements
has_obo_namespace: chebi_ontology
has_related_synonym: Hauptgruppenelement
has_related_synonym: Hauptgruppenelemente
has_related_synonym: main group element
id: CHEBI:33318
in subset: 3 STAR

L-serine zwitterion
type: Class
subclass of: serine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-serine zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: L-serine
definition: A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-serine.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
inchikey: MTCFGRXMJLQNBG-REOHCLBHSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: [NH3+][C@@H](CO)C([O-])=O
database_cross_reference: MetaCyc:SER
has exact synonym: (2S)-2-ammonio-3-hydroxypropanoate
has exact synonym: L-serine zwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: L-serine
id: CHEBI:33384
in subset: 3 STAR

sulfur oxoacid
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoacid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacids of sulfur
has_related_synonym: sulfur oxoacids
id: CHEBI:33402
in subset: 3 STAR

hydracid
type: Class
subclass of: hydrogen molecular entity
subclass of: Restriction
  on property: has role
  some values from: CHEBI_39141
definition: A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
imported from: chebi.owl
has exact synonym: hydracid
has_obo_namespace: chebi_ontology
has_related_synonym: hydracids
id: CHEBI:33405
in subset: 3 STAR

pnictogen oxoacid
type: Class
subclass of: oxoacid
subclass of: pnictogen molecular entity
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen oxoacids
id: CHEBI:33408
in subset: 3 STAR

sulfur oxoacid derivative
type: Class
subclass of: sulfur molecular entity
subclass of: oxoacid derivative
imported from: chebi.owl
has exact synonym: sulfur oxoacid derivative
has_obo_namespace: chebi_ontology
has_related_synonym: sulfur oxoacid derivatives
id: CHEBI:33424
in subset: 3 STAR

monoatomic monoanion
type: Class
subclass of: monoatomic anion
subclass of: CHEBI_36830
imported from: chebi.owl
charge: -1
mass: 0.00000
smiles: [*-]
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic monoanions
id: CHEBI:33429
in subset: 3 STAR

elemental chlorine
type: Class
subclass of: chlorine molecular entity
subclass of: elemental halogen
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33431
in subset: 3 STAR

monoatomic chlorine
type: Class
subclass of: elemental chlorine
subclass of: monoatomic halogen
imported from: chebi.owl
charge: 0
formula: Cl
mass: 35.453
monoisotopicmass: 34.96885
has_obo_namespace: chebi_ontology
has_related_synonym: atomic chlorine
id: CHEBI:33432
in subset: 3 STAR

monoatomic halogen
type: Class
subclass of: monoatomic entity
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monoatomic halogens
id: CHEBI:33433
in subset: 3 STAR

elemental halogen
type: Class
subclass of: elemental molecular entity
imported from: chebi.owl
has exact synonym: elemental halogen
has_obo_namespace: chebi_ontology
has_related_synonym: elemental halogens
id: CHEBI:33434
in subset: 3 STAR

benzylic group
type: Class
subclass of: organyl group
definition: Arylmethyl groups and derivatives formed by substitution: ArCR2-.
imported from: chebi.owl
has exact synonym: benzylic group
has exact synonym: benzylic groups
has_obo_namespace: chebi_ontology
has_related_synonym: benzylic groups
has_related_synonym: groupe benzylique
id: CHEBI:33452
in subset: 3 STAR

phosphorus oxoacid
type: Class
subclass of: pnictogen oxoacid
subclass of: CHEBI_36360
definition: A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.
imported from: chebi.owl
has exact synonym: phosphorus oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: Oxosaeure des Phosphors
has_related_synonym: oxoacids of phosphorus
has_related_synonym: phosphorus oxoacids
id: CHEBI:33457
in subset: 3 STAR

pnictogen oxoanion
type: Class
subclass of: pnictogen molecular entity
subclass of: oxoanion
imported from: chebi.owl
has exact synonym: pnictogen oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: pnictogen oxoanions
id: CHEBI:33459
in subset: 3 STAR

phosphorus oxoanion
type: Class
subclass of: inorganic anion
subclass of: phosphorus molecular entity
subclass of: pnictogen oxoanion
imported from: chebi.owl
has exact synonym: phosphorus oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoanions of phosphorus
has_related_synonym: phosphorus oxoanions
id: CHEBI:33461
in subset: 3 STAR

elemental pnictogen
type: Class
subclass of: inorganic molecular entity
subclass of: elemental molecular entity
subclass of: pnictogen molecular entity
imported from: chebi.owl
has exact synonym: elemental pnictogen
has_obo_namespace: chebi_ontology
has_related_synonym: elemental pnictogens
id: CHEBI:33465
in subset: 3 STAR

sulfur oxoanion
type: Class
subclass of: sulfur molecular entity
subclass of: chalcogen oxoanion
imported from: chebi.owl
has exact synonym: sulfur oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoanions of sulfur
has_related_synonym: sulfur oxoanions
id: CHEBI:33482
in subset: 3 STAR

chalcogen oxoacid
type: Class
subclass of: oxoacid
subclass of: chalcogen molecular entity
subclass of: Restriction
  on property: has role
  some values from: inorganic acid
imported from: chebi.owl
has exact synonym: chalcogen oxoacid
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen oxoacids
id: CHEBI:33484
in subset: 3 STAR

chalcogen oxoanion
type: Class
subclass of: chalcogen molecular entity
subclass of: oxoanion
imported from: chebi.owl
has exact synonym: chalcogen oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: chalcogen oxoanions
id: CHEBI:33485
in subset: 3 STAR

transition element molecular entity
type: Class
subclass of: molecular entity
definition: A molecular entity containing one or more atoms of a transition element.
imported from: dron.owl
has_related_synonym: transition element molecular entities
has_related_synonym: transition metal molecular entity
id: CHEBI:33497

sulfur hydride
type: Class
subclass of: sulfur molecular entity
subclass of: CHEBI_36902
imported from: chebi.owl
has exact synonym: sulfur hydride
has_obo_namespace: chebi_ontology
has_related_synonym: hydrides of sulfur
has_related_synonym: sulfur hydrides
has_related_synonym: sulphur hydrides
id: CHEBI:33535
in subset: 3 STAR

sulfonate
type: Class
subclass of: sulfur oxoanion
subclass of: Restriction
  on property: is conjugate base of
  some values from: sulfonic acid
definition: The sulfur oxoanion formed by deprotonation of sulfonic acid.
imported from: chebi.owl
charge: -1
formula: HO3S
inchi: InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1
inchikey: BDHFUVZGWQCTTF-UHFFFAOYSA-M
mass: 81.07214
monoisotopicmass: 80.96519
smiles: [H]S([O-])(=O)=O
database_cross_reference: Gmelin:971569
has exact synonym: hydridotrioxidosulfate(1-)
has_obo_namespace: chebi_ontology
has_related_synonym: SHO3(-)
has_related_synonym: [SHO3](-)
has_related_synonym: sulfonates
id: CHEBI:33543
in subset: 3 STAR

organosulfonic acid
type: Class
subclass of: organosulfur compound
subclass of: sulfonic acid derivative
subclass of: CHEBI_64709
subclass of: Restriction
  on property: has part
  some values from: sulfo group
subclass of: Restriction
  on property: has part
  some values from: organyl group
subclass of: Restriction
  on property: is conjugate acid of
  some values from: organosulfonate oxoanion
definition: An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon.
imported from: chebi.owl
charge: 0
formula: HO3SR
mass: 81.07100
monoisotopicmass: 80.96464
smiles: OS([*])(=O)=O
has_obo_namespace: chebi_ontology
has_related_synonym: organosulfonic acids
has_related_synonym: sulfonic acids
id: CHEBI:33551
in subset: 3 STAR

sulfonic acid derivative
type: Class
subclass of: sulfur oxoacid derivative
subclass of: Restriction
  on property: has functional parent
  some values from: sulfonic acid
imported from: chebi.owl
has exact synonym: sulfonic acid derivative
has_obo_namespace: chebi_ontology
has_related_synonym: derivatives of sulfonic acid
has_related_synonym: sulfonic acid derivatives
id: CHEBI:33552
in subset: 3 STAR

organosulfonate oxoanion
type: Class
subclass of: organic anion
subclass of: Restriction
  on property: has functional parent
  some values from: sulfonate
subclass of: Restriction
  on property: is conjugate base of
  some values from: organosulfonic acid
definition: An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.
imported from: chebi.owl
charge: -1
formula: O3SR
mass: 80.064
monoisotopicmass: 79.95681
smiles: *S([O-])(=O)=O
has_obo_namespace: chebi_ontology
has_related_synonym: organosulfonate
has_related_synonym: organosulfonate oxoanions
has_related_synonym: organosulfonates
id: CHEBI:33554
in subset: 3 STAR

alpha-amino-acid anion
type: Class
subclass of: CHEBI_37022
subclass of: Restriction
  on property: is conjugate base of
  some values from: alpha-amino acid
definition: An amino-acid anion obtained by deprotonation of any alpha-amino acid.
imported from: chebi.owl
has exact synonym: alpha-amino-acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino acid anions
has_related_synonym: alpha-amino-acid anions
id: CHEBI:33558
in subset: 3 STAR

s-block element atom
type: Class
subclass of: atom
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: s-block element
has_related_synonym: s-block elements
id: CHEBI:33559
in subset: 3 STAR

p-block element atom
type: Class
subclass of: main group element atom
definition: Any main group element atom belonging to the p-block of the periodic table.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: p-block element
has_related_synonym: p-block elements
id: CHEBI:33560
in subset: 3 STAR

benzenediols
type: Class
subclass of: phenols
imported from: chebi.owl
has_alternative_id: CHEBI:22705
has_alternative_id: CHEBI:22711
has_obo_namespace: chebi_ontology
id: CHEBI:33570
in subset: 3 STAR

resorcinols
type: Class
subclass of: benzenediols
definition: Any benzenediol in which the two hydroxy groups are meta to one another.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33572
in subset: 3 STAR

carboxylic acid
type: Class
subclass of: oxoacid
subclass of: carbon oxoacid
subclass of: CHEBI_36586
subclass of: CHEBI_50860
subclass of: CHEBI_64709
subclass of: Restriction
  on property: has part
  some values from: CHEBI_46883
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carboxylic acid anion
definition: A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
definition: An oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: CHO2R
mass: 45.01740
monoisotopicmass: 44.99765
smiles: OC([*])=O
has_alternative_id: CHEBI:13428
has_alternative_id: CHEBI:13627
has_alternative_id: CHEBI:23027
database_cross_reference: CiteXplore:17147560
database_cross_reference: CiteXplore:18433345
database_cross_reference: PMID:17147560
database_cross_reference: PMID:18433345
database_cross_reference: Wikipedia:Carboxylic_acid
has exact synonym: carboxylic acid
has exact synonym: carboxylic acids
has_obo_namespace: chebi_ontology
has_related_synonym: CHO2R
has_related_synonym: Carbonsaeure
has_related_synonym: Carbonsaeuren
has_related_synonym: Karbonsaeure
has_related_synonym: OC([*])=O
has_related_synonym: RC(=O)OH
has_related_synonym: acide carboxylique
has_related_synonym: acides carboxyliques
has_related_synonym: acido carboxilico
has_related_synonym: acidos carboxilicos
id: CHEBI:33575
in subset: 3 STAR

sulfur-containing carboxylic acid
type: Class
subclass of: organosulfur compound
subclass of: carboxylic acid
definition: Any carboxylic acid having a sulfur substituent.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: S-containing carboxylic acid
has_related_synonym: S-containing carboxylic acids
has_related_synonym: sulfur-containing carboxylic acids
id: CHEBI:33576
in subset: 3 STAR

main group molecular entity
type: Class
subclass of: molecular entity
subclass of: Restriction
  on property: has part
  some values from: main group element atom
definition: A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: main group compounds
has_related_synonym: main group molecular entities
id: CHEBI:33579
in subset: 3 STAR

carbon group molecular entity
type: Class
subclass of: p-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: carbon group element atom
imported from: chebi.owl
imported from: dron.owl
has exact synonym: carbon group molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: carbon group molecular entities
id: CHEBI:33582
in subset: 3 STAR

cyclic compound
type: Class
subclass of: molecule
subclass of: CHEBI_36357
definition: Any molecule that consists of a series of atoms joined together to form a ring.
imported from: chebi.owl
imported from: dron.owl
database_cross_reference: Wikipedia:Cyclic_compound
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic compounds
id: CHEBI:33595
in subset: 3 STAR

homocyclic compound
type: Class
subclass of: cyclic compound
definition: A cyclic compound having as ring members atoms of the same element only.
imported from: chebi.owl
has exact synonym: homocyclic compound
has exact synonym: homocyclic compounds
has_obo_namespace: chebi_ontology
has_related_synonym: isocyclic compounds
id: CHEBI:33597
in subset: 3 STAR

carbocyclic compound
type: Class
subclass of: homocyclic compound
subclass of: organic cyclic compound
definition: A homocyclic compound in which all of the ring members are carbon atoms.
imported from: chebi.owl
has exact synonym: carbocyclic compound
has exact synonym: carbocyclic compounds
has_obo_namespace: chebi_ontology
has_related_synonym: carbocycle
id: CHEBI:33598
in subset: 3 STAR

spiro compound
type: Class
subclass of: polycyclic compound
definition: A compound having one atom as the only common member of two rings.
imported from: chebi.owl
has exact synonym: spiro compound
has exact synonym: spiro compounds
has_obo_namespace: chebi_ontology
has_related_synonym: spiro-fused compounds
has_related_synonym: spirocycle
has_related_synonym: spirocycles
has_related_synonym: spirocyclic compound
has_related_synonym: spirocyclic compounds
has_related_synonym: spirofused compounds
id: CHEBI:33599
in subset: 3 STAR

hydrogen molecular entity
type: Class
subclass of: s-block molecular entity
subclass of: Restriction
  on property: has part
  some values from: CHEBI_49637
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: hydrogen compounds
has_related_synonym: hydrogen molecular entities
id: CHEBI:33608
in subset: 3 STAR

polycyclic compound
type: Class
subclass of: cyclic compound
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: polycyclic compounds
id: CHEBI:33635
in subset: 3 STAR

bicyclic compound
type: Class
subclass of: cyclic compound
definition: A molecule that features two fused rings.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: bicyclic compounds
id: CHEBI:33636
in subset: 3 STAR

ortho-fused compound
type: Class
subclass of: fused compound
definition: A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms.
imported from: chebi.owl
has exact synonym: ortho-fused polycyclic compounds
has_obo_namespace: chebi_ontology
has_related_synonym: ortho-fused compounds
id: CHEBI:33637
in subset: 3 STAR

olefin
type: Class
subclass of: hydrocarbon
subclass of: CHEBI_78840
definition: Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes.
imported from: chebi.owl
has exact synonym: olefin
has exact synonym: olefins
has_obo_namespace: chebi_ontology
has_related_synonym: olefins
id: CHEBI:33641
in subset: 3 STAR

acyclic olefin
type: Class
subclass of: olefin
definition: Acyclic branched or unbranched hydrocarbons having one or more carbon-carbon double bond.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: acyclic olefins
id: CHEBI:33645
in subset: 3 STAR

aliphatic compound
type: Class
subclass of: CHEBI_50860
definition: Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.
imported from: chebi.owl
has exact synonym: aliphatic compounds
has_obo_namespace: chebi_ontology
id: CHEBI:33653
in subset: 3 STAR

aromatic compound
type: Class
subclass of: cyclic compound
definition: A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: aromatic compounds
has exact synonym: aromatic molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: aromatics
has_related_synonym: aromatische Verbindungen
id: CHEBI:33655
in subset: 3 STAR

arene
type: Class
subclass of: organic aromatic compound
subclass of: cyclic hydrocarbon
definition: Any monocyclic or polycyclic aromatic hydrocarbon.
imported from: chebi.owl
has exact synonym: arene
has exact synonym: arenes
has_obo_namespace: chebi_ontology
has_related_synonym: aromatic hydrocarbons
id: CHEBI:33658
in subset: 3 STAR

organic aromatic compound
type: Class
subclass of: aromatic compound
subclass of: organic cyclic compound
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic aromatic compounds
id: CHEBI:33659
in subset: 3 STAR

monocyclic compound
type: Class
subclass of: cyclic compound
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monocyclic compounds
id: CHEBI:33661
in subset: 3 STAR

annulene
type: Class
subclass of: monocyclic hydrocarbon
definition: A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms.
imported from: chebi.owl
has exact synonym: annulene
has exact synonym: annulenes
has_obo_namespace: chebi_ontology
id: CHEBI:33662
in subset: 3 STAR

cyclic hydrocarbon
type: Class
subclass of: hydrocarbon
subclass of: carbocyclic compound
imported from: chebi.owl
has exact synonym: cyclic hydrocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: cyclic hydrocarbons
id: CHEBI:33663
in subset: 3 STAR

monocyclic hydrocarbon
type: Class
subclass of: cyclic hydrocarbon
imported from: chebi.owl
has exact synonym: monocyclic hydrocarbon
has exact synonym: monocyclic hydrocarbons
has_obo_namespace: chebi_ontology
has_related_synonym: monocyclic hydrocarbons
id: CHEBI:33664
in subset: 3 STAR

polycyclic hydrocarbon
type: Class
subclass of: cyclic hydrocarbon
subclass of: carbopolycyclic compound
imported from: chebi.owl
has exact synonym: polycyclic hydrocarbon
has exact synonym: polycyclic hydrocarbons
has_obo_namespace: chebi_ontology
id: CHEBI:33666
in subset: 3 STAR

heteromonocyclic compound
type: Class
subclass of: monocyclic compound
subclass of: CHEBI 5686
imported from: chebi.owl
imported from: dron.owl
has exact synonym: heteromonocyclic compound
has exact synonym: heteromonocyclic compounds
has_obo_namespace: chebi_ontology
id: CHEBI:33670
in subset: 3 STAR

heteropolycyclic compound
type: Class
subclass of: polycyclic compound
subclass of: CHEBI 5686
definition: A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: heteropolycyclic compounds
has_obo_namespace: chebi_ontology
has_related_synonym: polyheterocyclic compounds
id: CHEBI:33671
in subset: 3 STAR

heterobicyclic compound
type: Class
subclass of: bicyclic compound
subclass of: CHEBI 5686
definition: A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: heterobicyclic compounds
has_obo_namespace: chebi_ontology
id: CHEBI:33672
in subset: 3 STAR

zinc group molecular entity
type: Class
subclass of: d-block molecular entity
imported from: dron.owl
has_related_synonym: zinc group molecular entities
id: CHEBI:33673

s-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: s-block element atom
definition: An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: s-block molecular entity
has_obo_namespace: chebi_ontology
has_related_synonym: s-block compounds
has_related_synonym: s-block molecular entities
id: CHEBI:33674
in subset: 3 STAR

p-block molecular entity
type: Class
subclass of: main group molecular entity
subclass of: Restriction
  on property: has part
  some values from: p-block element atom
definition: A main group molecular entity that contains one or more atoms of a p-block element.
definition: A p-block molecular entity is a molecular entity containing one or more atoms of a p-block element.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: p-block compounds
has_related_synonym: p-block molecular entities
has_related_synonym: p-block molecular entitiy
id: CHEBI:33675
in subset: 3 STAR

d-block molecular entity
type: Class
subclass of: transition element molecular entity
definition: A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.
imported from: dron.owl
has exact synonym: d-block molecular entity
has_related_synonym: d-block compounds
has_related_synonym: d-block molecular entities
id: CHEBI:33676

hydrides
type: Class
subclass of: hydrogen molecular entity
subclass of: CHEBI_37577
definition: Hydrides are chemical compounds of hydrogen with other chemical elements.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:33692
in subset: 3 STAR

oxygen hydride
type: Class
subclass of: CHEBI_36902
imported from: chebi.owl
has exact synonym: oxygen hydride
has_obo_namespace: chebi_ontology
has_related_synonym: hydrides of oxygen
has_related_synonym: oxygen hydrides
id: CHEBI:33693
in subset: 3 STAR

biomacromolecule
type: Class
subclass of: macromolecule
subclass of: CHEBI_50860
definition: A macromolecule formed by a living organism.
imported from: chebi.owl
has exact synonym: biopolymer
has_obo_namespace: chebi_ontology
has_related_synonym: Biopolymere
has_related_synonym: biomacromolecules
has_related_synonym: biopolymers
id: CHEBI:33694
in subset: 3 STAR

nucleic acid
type: Class
subclass of: macromolecule
editor preferred label: nucleic acid
definition: A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
imported from: chebi.owl
imported from: obi.owl

ribonucleic acid
type: Class
subclass of: nucleic acid
editor preferred label: ribonucleic acid
definition: High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.
alternative term: RNA
imported from: chebi.owl
imported from: obi.owl

proteinogenic amino-acid residue
type: Class
subclass of: alpha-amino-acid residue
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: canonical amino-acid residue
has_related_synonym: canonical amino-acid residues
has_related_synonym: common amino acid residues
has_related_synonym: proteinogenic amino-acid residues
has_related_synonym: standard amino acid residues
has_related_synonym: standard amino-acid residues
id: CHEBI:33700
in subset: 3 STAR

polyatomic cation
type: Class
subclass of: CHEBI_36358
subclass of: CHEBI_36916
definition: A cation consisting of more than one atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: polyatomic cations
id: CHEBI:33702
in subset: 3 STAR

amino-acid cation
type: Class
subclass of: polyatomic cation
imported from: chebi.owl
has exact synonym: amino-acid cation
has_obo_namespace: chebi_ontology
has_related_synonym: amino acid cation
has_related_synonym: amino-acid cations
id: CHEBI:33703
in subset: 3 STAR

alpha-amino acid
type: Class
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: alpha-amino-acid anion
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_78608
definition: An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
imported from: chebi.owl
charge: 0
formula: C2H4NO2R
mass: 74.05870
monoisotopicmass: 74.02420
smiles: NC([*])C(O)=O
has_alternative_id: CHEBI:10208
has_alternative_id: CHEBI:13779
has_alternative_id: CHEBI:22442
has_alternative_id: CHEBI:2642
database_cross_reference: KEGG:C00045
database_cross_reference: KEGG:C05167
has exact synonym: alpha-amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: Amino acid
has_related_synonym: Amino acids
has_related_synonym: alpha-amino acids
has_related_synonym: alpha-amino carboxylic acids
id: CHEBI:33704
in subset: 3 STAR

gamma-amino acid
type: Class
subclass of: CHEBI_83820
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_71666
definition: A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group.
imported from: chebi.owl
has exact synonym: gamma-amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: gamma-amino acids
id: CHEBI:33707
in subset: 3 STAR

amino-acid residue
type: Class
subclass of: organic group
subclass of: Restriction
  on property: is substituent group from
  some values from: amino acid
definition: When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.
imported from: chebi.owl
has exact synonym: amino-acid residue
has_obo_namespace: chebi_ontology
has_related_synonym: amino acid residue
has_related_synonym: amino-acid residues
id: CHEBI:33708
in subset: 3 STAR

amino acid
type: Class
subclass of: carboxylic acid
subclass of: CHEBI_50047
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_37022
definition: A carboxylic acid containing one or more amino groups.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:13815
has_alternative_id: CHEBI:22477
database_cross_reference: Wikipedia:Amino_acid
has_obo_namespace: chebi_ontology
has_related_synonym: Aminocarbonsaeure
has_related_synonym: Aminokarbonsaeure
has_related_synonym: Aminosaeure
has_related_synonym: amino acids
id: CHEBI:33709
in subset: 3 STAR

alpha-amino-acid residue
type: Class
subclass of: amino-acid residue
subclass of: Restriction
  on property: is substituent group from
  some values from: alpha-amino acid
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino-acid residues
id: CHEBI:33710
in subset: 3 STAR

C-terminal amino-acid residue
type: Class
subclass of: amino-acid residue
definition: The residue in a peptide that has a free carboxyl group, or at least does not acylate another amino-acid residue, is called C-terminal.
imported from: chebi.owl
has exact synonym: C-terminal amino-acid residue
has exact synonym: C-terminal residue
has_obo_namespace: chebi_ontology
has_related_synonym: C-terminal amino-acid residues
has_related_synonym: carboxyl-terminal residue
id: CHEBI:33711
in subset: 3 STAR

C-terminal alpha-amino-acid residue
type: Class
subclass of: alpha-amino-acid residue
subclass of: C-terminal amino-acid residue
definition: Any C-terminal amino-acid residue derived from an alpha-amino-acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: C-terminal alpha-amino-acid residues
id: CHEBI:33713
in subset: 3 STAR

C-terminal proteinogenic amino-acid residue
type: Class
subclass of: proteinogenic amino-acid residue
subclass of: C-terminal alpha-amino-acid residue
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_90782
definition: Any C-terminal alpha-amino-acid residue derived from a proteinogenic amino acid.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: C-terminal canonical amino-acid residue
has_related_synonym: C-terminal canonical amino-acid residues
has_related_synonym: C-terminal proteinogenic amino-acid residues
id: CHEBI:33717
in subset: 3 STAR

alpha-amino-acid cation
type: Class
subclass of: amino-acid cation
imported from: chebi.owl
has exact synonym: alpha-amino-acid cation
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino acid cations
has_related_synonym: alpha-amino-acid cations
id: CHEBI:33719
in subset: 3 STAR

carbohydrate acid
type: Class
subclass of: carbohydrate
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carbohydrate acid anion
imported from: chebi.owl
has exact synonym: carbohydrate acid
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acids
id: CHEBI:33720
in subset: 3 STAR

carbohydrate acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: carbohydrate acid
imported from: chebi.owl
has exact synonym: carbohydrate acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: carbohydrate acid anions
id: CHEBI:33721
in subset: 3 STAR

proteinogenic amino-acid residue cation
type: Class
subclass of: proteinogenic amino-acid residue
subclass of: alpha-amino-acid residue cation
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: canonical amino-acid residue cation
has_related_synonym: canonical amino-acid residue cations
has_related_synonym: proteinogenic amino-acid residue cations
id: CHEBI:33727
in subset: 3 STAR

captopril
type: Class
subclass of: CHEBI_46701
subclass of: CHEBI_46766
subclass of: CHEBI_47908
subclass of: CHEBI_84186
subclass of: Restriction
  on property: has role
  some values from: EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
subclass of: Restriction
  on property: has role
  some values from: antihypertensive agent
subclass of: Restriction
  on property: has role
  some values from: inhibitor
definition: A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug.
definition source: Reference: PMID: 9187274
imported from: chebi.owl
charge: 0
formula: C9H15NO3S
inchi: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
inchikey: FAKRSMQSSFJEIM-RQJHMYQMSA-N
mass: 217.28500
monoisotopicmass: 217.07726
smiles: C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
database_cross_reference: Beilstein:477887
database_cross_reference: CAS:62571-86-2
database_cross_reference: DrugBank:DB01197
database_cross_reference: Drug_Central:484
database_cross_reference: KEGG:D00251
database_cross_reference: LINCS:LSM-5648
database_cross_reference: PMID:23137627
database_cross_reference: PMID:23161035
database_cross_reference: PMID:23278692
database_cross_reference: PMID:23299024
database_cross_reference: PMID:23328620
database_cross_reference: PMID:23397376
database_cross_reference: PMID:23410042
database_cross_reference: PMID:23422724
database_cross_reference: PMID:23429803
database_cross_reference: PMID:23435971
database_cross_reference: PMID:2420897
database_cross_reference: Patent:US4046889
database_cross_reference: Patent:US4105776
database_cross_reference: Wikipedia:Captopril
has exact synonym: 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
has_related_synonym: Acepress
has_related_synonym: Apopril
has_related_synonym: CP
has_related_synonym: Capoten
has_related_synonym: Captolane
has_related_synonym: Captopryl
has_related_synonym: Captoril
has_related_synonym: Cesplon
has_related_synonym: D-2-methyl-3-mercaptopropanoyl-L-proline
has_related_synonym: D-3-mercapto-2-methylpropanoyl-L-proline
has_related_synonym: Dilabar
has_related_synonym: Garranil
has_related_synonym: Hypertil
has_related_synonym: L-Captopril
has_related_synonym: Lopirin
has_related_synonym: Tenosbon
has_related_synonym: TensoboInOwln
has_related_synonym: Tensoprel
has_related_synonym: captopril
has_related_synonym: captoprilum
id: CHEBI:3380
in subset: 3 STAR

organic hydroxy compound
type: Class
subclass of: hydroxides
subclass of: CHEBI_50860
definition: An organic compound having at least one hydroxy group attached to a carbon atom.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:64710
has exact synonym: hydroxy compounds
has_obo_namespace: chebi_ontology
has_related_synonym: organic alcohol
has_related_synonym: organic hydroxy compounds
id: CHEBI:33822
in subset: 3 STAR

organic cyclic compound
type: Class
subclass of: cyclic compound
subclass of: CHEBI_50860
subclass of: CHEBI_72695
definition: Any organic molecule that consists of atoms connected in the form of a ring.
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic cyclic compounds
id: CHEBI:33832
in subset: 3 STAR

heteroarene
type: Class
subclass of: organic heterocyclic compound
subclass of: organic aromatic compound
definition: A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
imported from: chebi.owl
imported from: dron.owl
has exact synonym: heteroarenes
has_obo_namespace: chebi_ontology
has_related_synonym: hetarenes
id: CHEBI:33833
in subset: 3 STAR

benzenoid aromatic compound
type: Class
subclass of: carbocyclic compound
subclass of: organic aromatic compound
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: benzenoid aromatic compounds
has_related_synonym: benzenoid compound
id: CHEBI:33836
in subset: 3 STAR

nucleoside
type: Class
subclass of: N-glycosyl compound
subclass of: oxolanes
subclass of: CHEBI_61120
subclass of: Restriction
  on property: has functional parent
  some values from: carbohydrate
definition: An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents.
definition: Nucleosides are ribosyl or deoxyribosyl derivatives of the pyrimidine or purine bases adenine, guanine, xanthine, thymine, cytosine, and uracil.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C5H8O3R2
mass: 116.115
monoisotopicmass: 116.04734
smiles: [C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO
has_alternative_id: CHEBI:13661
has_alternative_id: CHEBI:25611
has_alternative_id: CHEBI:7647
database_cross_reference: KEGG COMPOUND:C00801
database_cross_reference: KEGG:C00801
database_cross_reference: Wikipedia:Nucleoside
has exact synonym: Nucleoside
has exact synonym: nucleoside
has exact synonym: nucleosides
has_obo_namespace: chebi_ontology
has_related_synonym: C5H9O4R
has_related_synonym: a nucleoside
has_related_synonym: nucleosides
id: CHEBI:33838
in subset: 3 STAR

macromolecule
type: Class
subclass of: molecular entity
subclass of: CHEBI_36357
editor preferred label: macromolecule
definition: A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
alternative term: polymer
imported from: chebi.owl
imported from: dron.owl
imported from: obi.owl
database_cross_reference: Wikipedia:Macromolecule
has exact synonym: macromolecule
has_obo_namespace: chebi_ontology
has_related_synonym: macromolecules
has_related_synonym: polymer
has_related_synonym: polymer molecule
has_related_synonym: polymers
id: CHEBI:33839
in subset: 3 STAR

(-)-anisomycin
type: Class
subclass of: organonitrogen heterocyclic antibiotic
subclass of: CHEBI_46777
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P39023
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P40429
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P55769
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P61313
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P61927
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P62750
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P62829
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P62913
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P62917
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR P84098
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR Q96L21
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR Q9UHA3
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR Q9UNX3
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: has role
  some values from: anticoronaviral agent
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has role
  some values from: antiparasitic agent
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48001
subclass of: Restriction
  on property: has role
  some values from: CHEBI_59517
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
definition source: PMID: 24841273
definition source: https://www.drugbank.ca/drugs/DB07374
imported from: chebi.owl
charge: 0
formula: C14H19NO4
inchi: InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1
inchikey: YKJYKKNCCRKFSL-RDBSUJKOSA-N
mass: 265.30500
monoisotopicmass: 265.13141
has_alternative_id: CHEBI:2737
has_alternative_id: CHEBI:40748
database_cross_reference: Beilstein:20705
database_cross_reference: CAS:22862-76-6
database_cross_reference: DrugBank:DB07374
database_cross_reference: KEGG:C11281
database_cross_reference: LINCS:LSM-4047
database_cross_reference: PDBeChem:ANM
database_cross_reference: PMID:16005213
database_cross_reference: PMID:22004851
database_cross_reference: PMID:23192275
database_cross_reference: PMID:23525555
database_cross_reference: PMID:23582782
database_cross_reference: PMID:24333448
database_cross_reference: PMID:6834379
database_cross_reference: Reaxys:20705
database_cross_reference: Wikipedia:Anisomycin
has exact synonym: (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
has_obo_namespace: chebi_ontology
has_related_synonym: 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate
has_related_synonym: 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate
has_related_synonym: 2-p-Methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidine
has_related_synonym: Anisomycin
id: CHEBI:338412
in subset: 3 STAR

aromatic annulene
type: Class
subclass of: annulene
subclass of: monocyclic arene
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: aromatic annulenes
id: CHEBI:33842
in subset: 3 STAR

monocyclic arene
type: Class
subclass of: arene
definition: A monocyclic aromatic hydrocarbon.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: monocyclic arenes
id: CHEBI:33847
in subset: 3 STAR

polycyclic arene
type: Class
subclass of: arene
subclass of: polycyclic hydrocarbon
subclass of: Restriction
  on property: has role
  some values from: endocrine disruptor
subclass of: Restriction
  on property: has role
  some values from: CHEBI_50903
definition: A polycyclic aromatic hydrocarbon.
imported from: chebi.owl
database_cross_reference: PMID:15198916
database_cross_reference: PMID:25679824
database_cross_reference: Wikipedia:Polycyclic_aromatic_hydrocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: PAH
has_related_synonym: PAHs
has_related_synonym: polycyclic arenes
has_related_synonym: polycyclic aromatic hydrocarbons
id: CHEBI:33848
in subset: 3 STAR

phenols
type: Class
subclass of: organic aromatic compound
subclass of: organic hydroxy compound
definition: Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
imported from: chebi.owl
charge: 0
formula: C6HOR5
mass: 89.072
monoisotopicmass: 89.00274
smiles: C1(=C(C(=C(C(=C1*)*)*)*)*)O
has_alternative_id: CHEBI:13664
has_alternative_id: CHEBI:13825
has_alternative_id: CHEBI:25969
has_alternative_id: CHEBI:2857
database_cross_reference: KEGG:C15584
database_cross_reference: MetaCyc:Phenols
database_cross_reference: Wikipedia:Phenols
has exact synonym: phenols
has_obo_namespace: chebi_ontology
has_related_synonym: Aryl alcohol
has_related_synonym: a phenol
has_related_synonym: arenols
id: CHEBI:33853
in subset: 3 STAR

aromatic alcohol
type: Class
subclass of: alcohol
subclass of: organic aromatic compound
definition: Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
imported from: chebi.owl
charge: 0
formula: HOR
mass: 17.007
monoisotopicmass: 17.00274
smiles: *O
has_alternative_id: CHEBI:13818
has_alternative_id: CHEBI:22620
has_alternative_id: CHEBI:22640
has_alternative_id: CHEBI:2831
has_obo_namespace: chebi_ontology
has_related_synonym: an aromatic alcohol
has_related_synonym: aromatic alcohols
has_related_synonym: aryl alcohol
has_related_synonym: aryl alcohols
id: CHEBI:33854
in subset: 3 STAR

aromatic amino acid
type: Class
subclass of: organic aromatic compound
subclass of: amino acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_63473
subclass of: Restriction
  on property: is tautomer of
  some values from: CHEBI_76042
definition: An amino acid whose structure includes an aromatic ring.
imported from: chebi.owl
charge: 0
formula: C2H4NO2R
mass: 88.085
monoisotopicmass: 74.02420
has_alternative_id: CHEBI:13820
has_alternative_id: CHEBI:22623
has_alternative_id: CHEBI:2835
database_cross_reference: KEGG:C01021
database_cross_reference: Wikipedia:Aromatic_amino_acid
has exact synonym: Aromatic amino acid
has_obo_namespace: chebi_ontology
has_related_synonym: aromatic amino acids
id: CHEBI:33856
in subset: 3 STAR

aromatic carboxylic acid
type: Class
subclass of: carboxylic acid
subclass of: organic aromatic compound
subclass of: Restriction
  on property: is conjugate acid of
  some values from: CHEBI_91007
definition: Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.
imported from: chebi.owl
has_alternative_id: CHEBI:13817
has_alternative_id: CHEBI:13821
has_alternative_id: CHEBI:2830
has_obo_namespace: chebi_ontology
has_related_synonym: aromatic carboxylic acids
id: CHEBI:33859
in subset: 3 STAR

aromatic amine
type: Class
subclass of: organic aromatic compound
subclass of: CHEBI_50047
definition: An amino compound in which the amino group is linked directly to an aromatic system.
imported from: chebi.owl
has_alternative_id: CHEBI:13827
has_alternative_id: CHEBI:22622
has_alternative_id: CHEBI:22646
has_alternative_id: CHEBI:2834
has_alternative_id: CHEBI:2863
has_obo_namespace: chebi_ontology
has_related_synonym: aromatic amines
has_related_synonym: aryl amine
has_related_synonym: aryl amines
has_related_synonym: arylamine
has_related_synonym: arylamines
id: CHEBI:33860
in subset: 3 STAR

reagent
type: Class
subclass of: application
definition: A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
imported from: chebi.owl
has exact synonym: reagent
has_obo_namespace: chebi_ontology
has_related_synonym: reactif
has_related_synonym: reactivo
has_related_synonym: reagents
id: CHEBI:33893
in subset: 3 STAR

molluscicide
type: Class
subclass of: pesticide
definition: A substance used to destroy pests of the phylum Mollusca.
imported from: chebi.owl
database_cross_reference: Wikipedia:Molluscicide
has_obo_namespace: chebi_ontology
has_related_synonym: molluscicides
id: CHEBI:33904
in subset: 3 STAR

macronutrient
type: Class
subclass of: nutrient
definition: Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: macronutrients
id: CHEBI:33937
in subset: 3 STAR

halide salt
type: Class
subclass of: salt
subclass of: CHEBI_37578
subclass of: Restriction
  on property: has part
  some values from: halide anion
imported from: chebi.owl
imported from: dron.owl
has_obo_namespace: chebi_ontology
has_related_synonym: halide salts
has_related_synonym: halides
id: CHEBI:33958
in subset: 3 STAR

Delta(1)-progesterone
type: Class
subclass of: CHEBI_36885
subclass of: CHEBI_77166
subclass of: Restriction
  on property: has functional parent
  some values from: progesterone
subclass of: Restriction
  on property: has parent hydride
  some values from: steroid fundamental parent
definition: A 3-oxo Delta(4)-steroid that is progesterone which has been oxidised to introduce a double bond between positions 1 and 2.
imported from: chebi.owl
charge: 0
formula: C21H28O2
inchi: InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h8,10,12,16-19H,4-7,9,11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
inchikey: QIEPWCSVQYUPIY-LEKSSAKUSA-N
mass: 312.44582
monoisotopicmass: 312.20893
database_cross_reference: Beilstein:1999508
database_cross_reference: CAS:1162-54-5
database_cross_reference: KEGG:C14677
database_cross_reference: Reaxys:1999508
has exact synonym: pregna-1,4-diene-3,20-dione
has_obo_namespace: chebi_ontology
has_related_synonym: 1,2-dehydroprogesterone
has_related_synonym: 1,2-didehydroprogesterone
has_related_synonym: 1-Dehydroprogesterone
has_related_synonym: 3,20-dioxo-1,4-pregnadiene
has_related_synonym: 3,20-dioxo-pregna-1,4-diene
has_related_synonym: Pregna-1,4-diene-3,20-dione
has_related_synonym: delta1-Progesterone
id: CHEBI:34073
in subset: 3 STAR

carnitinium
type: Class
subclass of: quaternary ammonium ion
subclass of: Restriction
  on property: has role
  some values from: CHEBI_75771
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77746
subclass of: Restriction
  on property: has functional parent
  some values from: gamma-amino-beta-hydroxybutyric acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: carnitine
definition: A quaternary ammonium ion that is the the conjugate acid of carnitine.
imported from: chebi.owl
charge: +1
formula: C7H16NO3
inchi: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/p+1
inchikey: PHIQHXFUZVPYII-UHFFFAOYSA-O
mass: 162.20688
monoisotopicmass: 162.11247
smiles: C[N+](C)(C)CC(O)CC(O)=O
database_cross_reference: CAS:406-76-8
database_cross_reference: CAS:461-06-3
database_cross_reference: KEGG:C00487
has exact synonym: 3-carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium
has_obo_namespace: chebi_ontology
has_related_synonym: 3-hydroxy-4-(trimethylammonio)butanoic acid
has_related_synonym: Carnitine
id: CHEBI:3424
in subset: 3 STAR

mevastatin
type: Class
subclass of: hexahydronaphthalenes
subclass of: polyketide
subclass of: carboxylic ester
subclass of: CHEBI_75885
subclass of: CHEBI_87632
subclass of: Restriction
  on property: has role
  some values from: CHEBI_35718
subclass of: Restriction
  on property: has role
  some values from: CHEBI_68495
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76946
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76964
subclass of: Restriction
  on property: has role
  some values from: CHEBI_77255
definition: A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.
imported from: chebi.owl
charge: 0
formula: C23H34O5
inchi: InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1
inchikey: AJLFOPYRIVGYMJ-INTXDZFKSA-N
mass: 390.51310
monoisotopicmass: 390.24062
database_cross_reference: CAS:73573-88-3
database_cross_reference: DrugBank:DB06693
database_cross_reference: KEGG:C13963
database_cross_reference: KNApSAcK:C00000564
database_cross_reference: LINCS:LSM-4123
database_cross_reference: PMID:11283400
database_cross_reference: PMID:12403272
database_cross_reference: PMID:15274361
database_cross_reference: PMID:15531285
database_cross_reference: PMID:15786722
database_cross_reference: PMID:18672387
database_cross_reference: PMID:18936176
database_cross_reference: PMID:20629200
database_cross_reference: PMID:23918904
database_cross_reference: PMID:24462564
database_cross_reference: PMID:3170348
database_cross_reference: PMID:3719857
database_cross_reference: Patent:DE2524355
database_cross_reference: Patent:US3983140
database_cross_reference: Reaxys:3630717
database_cross_reference: Wikipedia:Mevastatin
has exact synonym: (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
has exact synonym: Mevastatin
has exact synonym: mevastatin
has_obo_namespace: chebi_ontology
has_related_synonym: CS 500
has_related_synonym: Compactin
has_related_synonym: ML 236 B
has_related_synonym: ML-236B
has_related_synonym: antibiotic ML 236B
has_related_synonym: mevastatin
has_related_synonym: mevastatina
has_related_synonym: mevastatine
has_related_synonym: mevastatinum
id: CHEBI:34848
in subset: 3 STAR

nocodazole
type: Class
subclass of: benzimidazoles
subclass of: carbamate ester
subclass of: thiophenes
subclass of: CHEBI_76224
subclass of: Restriction
  on property: chemical has protein target
  some values from: PR O60760
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_1335626
subclass of: Restriction
  on property: has role
  some values from: antineoplastic agent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_60832
subclass of: Restriction
  on property: has role
  some values from: CHEBI_61951
subclass of: Restriction
  on property: has role
  some values from: CHEBI_64911
definition: A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.
definition source: PMID: 27783035; PMID: 24841273
definition source: https://www.drugbank.ca/drugs/DB08313
imported from: chebi.owl
charge: 0
formula: C14H11N3O3S
inchi: InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
inchikey: KYRVNWMVYQXFEU-UHFFFAOYSA-N
mass: 301.32000
monoisotopicmass: 301.05211
smiles: COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1
database_cross_reference: Beilstein:1085978
database_cross_reference: CAS:31430-18-9
database_cross_reference: DrugBank:DB08313
database_cross_reference: KEGG:C13719
database_cross_reference: KEGG:D05197
database_cross_reference: LINCS:LSM-2260
database_cross_reference: PDBeChem:NZO
database_cross_reference: PMID:11679255
database_cross_reference: PMID:20399776
database_cross_reference: PMID:22002881
database_cross_reference: PMID:23869451
database_cross_reference: PMID:518692
database_cross_reference: PMID:6384770
database_cross_reference: PMID:7199049
database_cross_reference: PMID:7284368
database_cross_reference: PMID:7344613
database_cross_reference: Reaxys:1085978
database_cross_reference: Wikipedia:Nocodazole
has exact synonym: methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
has_obo_namespace: chebi_ontology
has_related_synonym: (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester
has_related_synonym: N-(5-(2-thenoyl)-2-benzimidazolyl)carbamic acid methyl ester
has_related_synonym: N-(5-(2-thienoyl)-2-benzimidazolyl)carbamic acid methyl ester
has_related_synonym: R 17934
has_related_synonym: R-17934
has_related_synonym: R17,934
has_related_synonym: methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate
has_related_synonym: methyl N-(5-thenoyl-2-benzimidazolyl)carbamate
has_related_synonym: nocodazol
has_related_synonym: nocodazole
has_related_synonym: nocodazolum
has_related_synonym: oncodazole
id: CHEBI:34892
in subset: 3 STAR

teicoplanin A2
type: Class
subclass of: acetamides
subclass of: glycopeptide
subclass of: polyphenol
subclass of: aromatic ether
subclass of: CHEBI_51026
subclass of: CHEBI_83403
subclass of: Restriction
  on property: has role
  some values from: antimicrobial agent
subclass of: Restriction
  on property: has functional parent
  some values from: teicoplanin A3-1
definition: Any of the glycopeptides whose structure consists of teicoplanin A3-1 in which the hydroxy group of the di(aryloxy)-substituted phenol moiety has been converted to the corresponding 2-acylamino-2-deoxy-beta-D-glucoside. Members of the class differ only in the nature of the acyl group.
imported from: chebi.owl
charge: 0
formula: C79H78Cl2N9O33R
mass: 1752.414
monoisotopicmass: 1750.40791
database_cross_reference: KEGG:C13781
has_obo_namespace: chebi_ontology
has_related_synonym: teicoplanin A2-*
id: CHEBI:34994
in subset: 3 STAR

teicoplanin A2-1
type: Class
subclass of: teicoplanin A2
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: A teicoplanin A2 that has (4Z)-dec-4-enoyl as the variable N-acyl group.
imported from: chebi.owl
charge: 0
formula: C88H95Cl2N9O33
inchikey: SGSMSXWFVXNLOG-UCNABHHISA-N
mass: 1877.64200
monoisotopicmass: 1875.54093
database_cross_reference: CAS:91032-34-7
database_cross_reference: KEGG:C13587
database_cross_reference: Reaxys:6261779
has exact synonym: Teicoplanin A2-1
has_obo_namespace: chebi_ontology
has_related_synonym: (Z)-34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: (Z)-34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxo-4-decenyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: Teichomycin A2 factor 1
id: CHEBI:34995
in subset: 3 STAR

teicoplanin A2-3
type: Class
subclass of: teicoplanin A2
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: A teicoplanin A2 that has decanoyl as the variable N-acyl group.
imported from: chebi.owl
charge: 0
formula: C88H97Cl2N9O33
inchikey: BJNLLBUOHPVGFT-PKMGYIMSSA-N
mass: 1879.65800
monoisotopicmass: 1877.55658
database_cross_reference: CAS:91032-36-9
database_cross_reference: KEGG:C13588
database_cross_reference: Reaxys:6995259
has exact synonym: Teicoplanin A2-3
has_obo_namespace: chebi_ontology
has_related_synonym: 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: Teichomycin A2 factor 3
id: CHEBI:34996
in subset: 3 STAR

teicoplanin A2-4
type: Class
subclass of: teicoplanin A2
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: A teicoplanin A2 that has 8-methyldecanoyl as the variable N-acyl group.
imported from: chebi.owl
charge: 0
formula: C89H99Cl2N9O33
inchikey: KSPOYQQCANXEDC-WNTLLCOUSA-N
mass: 1893.68500
monoisotopicmass: 1891.57223
database_cross_reference: CAS:91032-37-0
database_cross_reference: KEGG:C13610
database_cross_reference: Reaxys:6261978
has exact synonym: Teicoplanin A2-4
has_obo_namespace: chebi_ontology
has_related_synonym: 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(8-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: Teichomycin A2 factor 4
id: CHEBI:34997
in subset: 3 STAR

teicoplanin A2-5
type: Class
subclass of: teicoplanin A2
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group.
imported from: chebi.owl
charge: 0
formula: C89H99Cl2N9O33
inchikey: FHBQKTSCJKPYIO-RLDSMAAISA-N
mass: 1893.68500
monoisotopicmass: 1891.57223
database_cross_reference: CAS:91032-38-1
database_cross_reference: KEGG:C13612
database_cross_reference: Reaxys:6995322
database_cross_reference: Reaxys:7509352
has exact synonym: Teicoplanin A2-5
has_obo_namespace: chebi_ontology
has_related_synonym: 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: Teichomycin A2 factor 5
id: CHEBI:34998
in subset: 3 STAR

teicoplanin A3-1
type: Class
subclass of: acetamides
subclass of: glycopeptide
subclass of: polyol
subclass of: polyphenol
subclass of: aromatic ether
subclass of: CHEBI_51026
subclass of: CHEBI_83403
subclass of: Restriction
  on property: has role
  some values from: CHEBI_76969
definition: A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido-2-deoxy-beta-D-glucoside.
imported from: chebi.owl
charge: 0
formula: C72H68Cl2N8O28
inchikey: SUFIXUDUKRJOBH-JSMFNTJWSA-N
mass: 1564.25300
monoisotopicmass: 1562.35201
database_cross_reference: CAS:93616-27-4
database_cross_reference: KEGG:C13613
database_cross_reference: PMID:1416858
database_cross_reference: Reaxys:6267420
has exact synonym: Teicoplanin A3-1
has_obo_namespace: chebi_ontology
has_related_synonym: 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone
has_related_synonym: 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone
id: CHEBI:34999
in subset: 3 STAR

nitrogen hydride
type: Class
subclass of: CHEBI_35881
subclass of: CHEBI_51143
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: nitrogen hydrides
id: CHEBI:35106
in subset: 3 STAR

azane
type: Class
subclass of: nitrogen hydride
definition: Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: azanes
id: CHEBI:35107
in subset: 3 STAR

terpene
type: Class
subclass of: hydrocarbon
subclass of: isoprenoid
definition: A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2].
imported from: chebi.owl
has exact synonym: terpene
has exact synonym: terpenes
has_obo_namespace: chebi_ontology
has_related_synonym: Terpen
has_related_synonym: terpenes
has_related_synonym: terpeno
has_related_synonym: terpenos
id: CHEBI:35186
in subset: 3 STAR

triterpene
type: Class
subclass of: terpene
definition: A C30 terpene.
imported from: chebi.owl
has exact synonym: triterpenes
has_obo_namespace: chebi_ontology
has_related_synonym: Triterpen
has_related_synonym: triterpenes
has_related_synonym: triterpeno
has_related_synonym: triterpenos
id: CHEBI:35191
in subset: 3 STAR

surfactant
type: Class
subclass of: CHEBI_63046
definition: A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces.
imported from: chebi.owl
has exact synonym: surfactant
has_obo_namespace: chebi_ontology
has_related_synonym: surface active agent
has_related_synonym: surfactants
id: CHEBI:35195
in subset: 3 STAR

cyclodepsipeptide
type: Class
subclass of: depsipeptide
subclass of: lactone
definition: A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring.
imported from: chebi.owl
has exact synonym: cyclodepsipeptides
has_obo_namespace: chebi_ontology
has_related_synonym: Cyclodepsipeptid
has_related_synonym: Zyklodepsipeptid
id: CHEBI:35213
in subset: 3 STAR

antimetabolite
type: Class
subclass of: CHEBI_52206
definition: A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
imported from: chebi.owl
database_cross_reference: Wikipedia:Antimetabolite
has exact synonym: antimetabolite
has_obo_namespace: chebi_ontology
has_related_synonym: antimetabolites
id: CHEBI:35221
in subset: 3 STAR

inhibitor
type: Class
subclass of: biological role
definition: A substance that diminishes the rate of a chemical reaction.
imported from: chebi.owl
has exact synonym: inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: inhibidor
has_related_synonym: inhibiteur
has_related_synonym: inhibitors
id: CHEBI:35222
in subset: 3 STAR

effector
type: Class
subclass of: CHEBI_52206
definition: A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site).
imported from: chebi.owl
database_cross_reference: Wikipedia:Effector_(biology)
has exact synonym: effector
has_obo_namespace: chebi_ontology
has_related_synonym: enzyme modulator
id: CHEBI:35224
in subset: 3 STAR

fossil fuel
type: Class
subclass of: fuel
definition: A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth.
imported from: chebi.owl
has exact synonym: fossil fuel
has_obo_namespace: chebi_ontology
id: CHEBI:35230
in subset: 3 STAR

L-cysteine zwitterion
type: Class
subclass of: cysteine zwitterion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: L-cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: L-cysteinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: D-cysteine zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: L-cysteine
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
inchikey: XUJNEKJLAYXESH-REOHCLBHSA-N
mass: 121.15922
monoisotopicmass: 121.01975
smiles: [NH3+][C@@H](CS)C([O-])=O
database_cross_reference: Gmelin:49993
has exact synonym: (2R)-2-ammonio-3-sulfanylpropanoate
has exact synonym: L-cysteine zwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: (2R)-2-ammonio-3-mercaptopropanoate
has_related_synonym: L-cysteine
id: CHEBI:35235
in subset: 3 STAR

D-cysteine zwitterion
type: Class
subclass of: cysteine zwitterion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: D-cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: D-cysteinium
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-cysteine zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: D-cysteine
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1
inchikey: XUJNEKJLAYXESH-UWTATZPHSA-N
mass: 121.15922
monoisotopicmass: 121.01975
smiles: [NH3+][C@H](CS)C([O-])=O
database_cross_reference: Gmelin:2352354
has exact synonym: (2S)-2-ammonio-3-sulfanylpropanoate
has exact synonym: D-cysteine zwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: (2S)-2-ammonio-3-mercaptopropanoate
has_related_synonym: D-cysteine
id: CHEBI:35236
in subset: 3 STAR

cysteine zwitterion
type: Class
subclass of: amino acid zwitterion
subclass of: Restriction
  on property: is conjugate acid of
  some values from: cysteinate(1-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: cysteinium
subclass of: Restriction
  on property: is tautomer of
  some values from: cysteine
imported from: chebi.owl
charge: 0
formula: C3H7NO2S
inchi: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
inchikey: XUJNEKJLAYXESH-UHFFFAOYSA-N
mass: 121.15922
monoisotopicmass: 121.01975
smiles: [NH3+]C(CS)C([O-])=O
database_cross_reference: Gmelin:49992
has exact synonym: 2-ammonio-3-sulfanylpropanoate
has exact synonym: cysteine zwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: (+)H3N-CH(CH2SH)-COO(-)
has_related_synonym: 2-ammonio-3-mercaptopropanoate
id: CHEBI:35237
in subset: 3 STAR

amino acid zwitterion
type: Class
subclass of: zwitterion
definition: The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.
imported from: chebi.owl
has exact synonym: amino acid zwitterion
has_obo_namespace: chebi_ontology
id: CHEBI:35238
in subset: 3 STAR

serine zwitterion
type: Class
subclass of: amino acid zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: serine
definition: An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amnio group of serine.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)
inchikey: MTCFGRXMJLQNBG-UHFFFAOYSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: [NH3+]C(CO)C([O-])=O
database_cross_reference: Beilstein:3935647
database_cross_reference: Gmelin:2060272
has exact synonym: 2-ammonio-3-hydroxypropanoate
has exact synonym: serine zwitterion
has_obo_namespace: chebi_ontology
id: CHEBI:35243
in subset: 3 STAR

D-serine zwitterion
type: Class
subclass of: serine zwitterion
subclass of: Restriction
  on property: is enantiomer of
  some values from: L-serine zwitterion
subclass of: Restriction
  on property: is tautomer of
  some values from: D-serine
definition: A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of D-serine.
imported from: chebi.owl
charge: 0
formula: C3H7NO3
inchi: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
inchikey: MTCFGRXMJLQNBG-UWTATZPHSA-N
mass: 105.09262
monoisotopicmass: 105.04259
smiles: [NH3+][C@H](CO)C([O-])=O
database_cross_reference: MetaCyc:D-SERINE
has exact synonym: (2R)-2-ammonio-3-hydroxypropanoate
has exact synonym: D-serine zwitterion
has_obo_namespace: chebi_ontology
has_related_synonym: D-serine
id: CHEBI:35247
in subset: 3 STAR

benzofurans
type: Class
subclass of: CHEBI_38104
subclass of: CHEBI_38166
imported from: chebi.owl
has_alternative_id: CHEBI:22721
has_obo_namespace: chebi_ontology
id: CHEBI:35259
in subset: 3 STAR

quaternary ammonium ion
type: Class
subclass of: organic cation
subclass of: ammonium ion derivative
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.
imported from: chebi.owl
charge: +1
formula: NR4
mass: 14.00670
monoisotopicmass: 14.00307
smiles: [*][N+]([*])([*])[*]
has_alternative_id: CHEBI:26470
has_alternative_id: CHEBI:8693
database_cross_reference: KEGG:C06703
has exact synonym: quaternary ammonium ion
has_obo_namespace: chebi_ontology
has_related_synonym: Quaternary amine
has_related_synonym: quaternary ammonium
has_related_synonym: quaternary ammonium ions
id: CHEBI:35267
in subset: 3 STAR

ammonium ion derivative
type: Class
subclass of: polyatomic cation
subclass of: CHEBI_51143
subclass of: Restriction
  on property: has parent hydride
  some values from: ammonium
definition: A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc).
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ammonium ion derivatives
has_related_synonym: azanium ion derivative
has_related_synonym: azanium ion derivatives
id: CHEBI:35274
in subset: 3 STAR

onium betaine
type: Class
subclass of: zwitterion
definition: Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom.
imported from: chebi.owl
has exact synonym: betaines
has_obo_namespace: chebi_ontology
has_related_synonym: onium betaines
id: CHEBI:35281
in subset: 3 STAR

ammonium betaine
type: Class
subclass of: quaternary nitrogen compound
subclass of: onium betaine
definition: Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ammonium betaines
id: CHEBI:35284
in subset: 3 STAR

iminium ion
type: Class
subclass of: organic cation
definition: Cations of structure R2C=N(+)R2.
imported from: chebi.owl
has exact synonym: iminium ion
has_obo_namespace: chebi_ontology
has_related_synonym: iminium cations
has_related_synonym: iminium ions
id: CHEBI:35286
in subset: 3 STAR

fused compound
type: Class
subclass of: polycyclic compound
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: fused compounds
has_related_synonym: fused polycyclic compounds
has_related_synonym: fused-ring polycyclic compound
has_related_synonym: fused-ring polycyclic compounds
has_related_synonym: polycyclic fused-ring compounds
id: CHEBI:35293
in subset: 3 STAR

carbopolycyclic compound
type: Class
subclass of: carbocyclic compound
subclass of: homopolycyclic compound
definition: A polyclic compound in which all of the ring members are carbon atoms.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: carbopolycyclic compounds
id: CHEBI:35294
in subset: 3 STAR

homopolycyclic compound
type: Class
subclass of: homocyclic compound
subclass of: polycyclic compound
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: homopolycyclic compounds
id: CHEBI:35295
in subset: 3 STAR

ortho-fused polycyclic arene
type: Class
subclass of: polycyclic arene
subclass of: ortho-fused polycyclic hydrocarbon
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ortho-fused polycyclic arenes
id: CHEBI:35296
in subset: 3 STAR

acene
type: Class
subclass of: ortho-fused polycyclic arene
subclass of: CHEBI_51269
definition: A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement.
imported from: chebi.owl
charge: 0
formula: C10H8.(C4H2)n
database_cross_reference: Wikipedia:Acene
has exact synonym: acene
has exact synonym: acenes
has_obo_namespace: chebi_ontology
has_related_synonym: Acen
has_related_synonym: Azen
has_related_synonym: polyacenes
id: CHEBI:35297
in subset: 3 STAR

glycosiduronic acid
type: Class
subclass of: glycoside
imported from: chebi.owl
has exact synonym: glycosiduronic acid
has_obo_namespace: chebi_ontology
has_related_synonym: glycosiduronic acids
id: CHEBI:35314
in subset: 3 STAR

deoxy hexoside
type: Class
subclass of: glycoside
imported from: chebi.owl
has exact synonym: deoxy hexoside
has_obo_namespace: chebi_ontology
has_related_synonym: deoxy hexosides
id: CHEBI:35315
in subset: 3 STAR

cephaeline
type: Class
subclass of: CHEBI_61692
subclass of: Restriction
  on property: has parent hydride
  some values from: CHEBI_36380
definition: A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions.
imported from: chebi.owl
charge: 0
formula: C28H38N2O4
inchi: InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1
inchikey: DTGZHCFJNDAHEN-OZEXIGSWSA-N
mass: 466.61240
monoisotopicmass: 466.28316
database_cross_reference: Beilstein:100615
database_cross_reference: CAS:483-17-0
database_cross_reference: KEGG:C09390
database_cross_reference: KNApSAcK:C00001835
database_cross_reference: LINCS:LSM-3808
database_cross_reference: PMID:11411558
database_cross_reference: PMID:11913711
database_cross_reference: PMID:11996324
database_cross_reference: PMID:12880315
database_cross_reference: PMID:13437707
database_cross_reference: PMID:18327911
database_cross_reference: PMID:20061395
database_cross_reference: PMID:20495341
database_cross_reference: PMID:21228475
database_cross_reference: PMID:2715231
database_cross_reference: PMID:6716976
database_cross_reference: Reaxys:100615
has exact synonym: 7',10,11-trimethoxyemetan-6'-ol
has exact synonym: Cephaeline
has_obo_namespace: chebi_ontology
has_related_synonym: Cephaelin
id: CHEBI:3533
in subset: 3 STAR

central nervous system stimulant
type: Class
subclass of: central nervous system drug
definition: Any drug that enhances the activity of the central nervous system.
imported from: chebi.owl
database_cross_reference: Wikipedia:Central_nervous_system_stimulants
has exact synonym: central nervous system stimulant
has_obo_namespace: chebi_ontology
has_related_synonym: CNS stimulant
has_related_synonym: analeptic
has_related_synonym: analeptic agent
has_related_synonym: analeptic drug
has_related_synonym: analeptics
has_related_synonym: central stimulant
id: CHEBI:35337
in subset: 3 STAR

amphetamines
type: Class
subclass of: amine
subclass of: Restriction
  on property: has role
  some values from: central nervous system stimulant
definition: Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: amphetamine drug
id: CHEBI:35338
in subset: 3 STAR

steroid
type: Class
subclass of: lipid
subclass of: CHEBI_51958
definition: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.
definition: Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from triterpenoids.
imported from: chebi.owl
imported from: dron.owl
charge: 0
formula: C19H31R
mass: 259.450
monoisotopicmass: 259.24258
smiles: C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C
has_alternative_id: CHEBI:13687
has_alternative_id: CHEBI:26768
has_alternative_id: CHEBI:9263
database_cross_reference: KEGG COMPOUND:C00377
database_cross_reference: KEGG:C00377
database_cross_reference: MetaCyc:Steroids
has exact synonym: Steroid
has exact synonym: steroids
has_obo_namespace: chebi_ontology
has_related_synonym: a steroid
id: CHEBI:35341
in subset: 3 STAR

17alpha-hydroxy steroid
type: Class
subclass of: CHEBI_36838
definition: The alpha-stereoisomer of 17-hydroxy steroid.
imported from: chebi.owl
has_alternative_id: CHEBI:13585
has_alternative_id: CHEBI:19174
has_alternative_id: CHEBI:782
database_cross_reference: KEGG:C03336
has_obo_namespace: chebi_ontology
has_related_synonym: 17-alpha-Hydroxysteroid
has_related_synonym: 17alpha-hydroxy steroids
id: CHEBI:35342
in subset: 3 STAR

21-hydroxy steroid
type: Class
subclass of: hydroxy steroid
imported from: chebi.owl
has_alternative_id: CHEBI:1300
has_alternative_id: CHEBI:13596
has_alternative_id: CHEBI:19803
database_cross_reference: KEGG:C02506
has_obo_namespace: chebi_ontology
has_related_synonym: 21-Hydroxysteroid
has_related_synonym: 21-hydroxy steroids
has_related_synonym: 21-hydroxysteroids
id: CHEBI:35344
in subset: 3 STAR

11beta-hydroxy steroid
type: Class
subclass of: CHEBI_36841
definition: Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration.
imported from: chebi.owl
charge: 0
formula: C19H31OR
mass: 275.450
monoisotopicmass: 275.23749
smiles: C12(CCCCC1CCC3C2[C@H](CC4(C3CCC4*)C)O)C
has_alternative_id: CHEBI:13774
has_alternative_id: CHEBI:19134
has_alternative_id: CHEBI:738
database_cross_reference: KEGG:C01058
has_obo_namespace: chebi_ontology
has_related_synonym: 11beta-Hydroxysteroid
has_related_synonym: 11beta-hydroxy steroids
has_related_synonym: 11beta-hydroxysteroids
has_related_synonym: an 11beta-hydroxysteroid
id: CHEBI:35346
in subset: 3 STAR

hydroxy steroid
type: Class
subclass of: organic hydroxy compound
subclass of: steroid
imported from: chebi.owl
has_alternative_id: CHEBI:24748
has_alternative_id: CHEBI:5814
database_cross_reference: KEGG:C02159
has_obo_namespace: chebi_ontology
has_related_synonym: Hydroxysteroid
has_related_synonym: hydroxy steroids
has_related_synonym: hydroxysteroids
id: CHEBI:35350
in subset: 3 STAR

organonitrogen compound
type: Class
subclass of: heteroorganic entity
subclass of: CHEBI_51143
definition: Any heteroorganic entity containing at least one carbon-nitrogen bond.
imported from: chebi.owl
imported from: dron.owl
has exact synonym: organonitrogen compounds
has_obo_namespace: chebi_ontology
has_related_synonym: organonitrogens
id: CHEBI:35352
in subset: 3 STAR

dicarboximide
type: Class
subclass of: imide
definition: An imide in which the two acyl substituents on nitrogen are carboacyl groups.
imported from: chebi.owl
charge: 0
formula: C2NO2R3
mass: 70.027
monoisotopicmass: 69.99290
smiles: [*]N(C([*])=O)C([*])=O
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboximides
id: CHEBI:35356
in subset: 3 STAR

sulfonamide
type: Class
subclass of: primary amide
subclass of: organosulfur compound
subclass of: sulfonic acid derivative
definition: An amide of a sulfonic acid RS(=O)2NR'2.
imported from: chebi.owl
charge: 0
formula: NO2SR3
mass: 78.07100
monoisotopicmass: 77.96497
smiles: [*]S(=O)(=O)N([*])[*]
database_cross_reference: PMID:11498380
database_cross_reference: PMID:2434548
database_cross_reference: PMID:26811268
database_cross_reference: PMID:26832216
database_cross_reference: Wikipedia:Sulfonamide
has exact synonym: sulfonamides
has_obo_namespace: chebi_ontology
has_related_synonym: sulfonamides
id: CHEBI:35358
in subset: 3 STAR

fatty acid
type: Class
subclass of: lipid
subclass of: monocarboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: fatty acid anion
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.
imported from: chebi.owl
charge: 0
formula: CHO2R
mass: 45.01740
monoisotopicmass: 44.99765
smiles: OC([*])=O
has_alternative_id: CHEBI:13633
has_alternative_id: CHEBI:24024
has_alternative_id: CHEBI:4984
database_cross_reference: KEGG:C00162
database_cross_reference: PMID:14287444
database_cross_reference: PMID:14300208
database_cross_reference: PMID:14328676
database_cross_reference: Wikipedia:Fatty_acid
has exact synonym: Fatty acid
has exact synonym: fatty acids
has_obo_namespace: chebi_ontology
has_related_synonym: Fettsaeure
has_related_synonym: Fettsaeuren
has_related_synonym: acide gras
has_related_synonym: acides gras
has_related_synonym: acido graso
has_related_synonym: acidos grasos
has_related_synonym: fatty acids
id: CHEBI:35366
in subset: 3 STAR

monosaccharide
type: Class
subclass of: carbohydrate
definition: Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.
imported from: chebi.owl
has_alternative_id: CHEBI:25407
has_alternative_id: CHEBI:6984
database_cross_reference: KEGG:C06698
has exact synonym: Monosaccharide
has exact synonym: monosaccharides
has_obo_namespace: chebi_ontology
has_related_synonym: Monosaccharid
has_related_synonym: Monosacharid
has_related_synonym: monosacarido
has_related_synonym: monosacaridos
id: CHEBI:35381
in subset: 3 STAR

aspartate(1-)
type: Class
subclass of: aspartate
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
subclass of: Restriction
  on property: is conjugate acid of
  some values from: aspartate(2-)
subclass of: Restriction
  on property: is conjugate base of
  some values from: aspartic acid
definition: An alpha-amino-acid anion that is the conjugate base of aspartic acid.
imported from: chebi.owl
charge: -1
formula: C4H6NO4
inchi: InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/p-1
inchikey: CKLJMWTZIZZHCS-UHFFFAOYSA-M
mass: 132.09478
monoisotopicmass: 132.03023
smiles: [NH3+]C(CC([O-])=O)C([O-])=O
has_alternative_id: CHEBI:22659
has_alternative_id: CHEBI:29992
has exact synonym: aspartate(1-)
has exact synonym: hydrogen aspartate
has_obo_namespace: chebi_ontology
has_related_synonym: 2-ammoniobutanedioate
has_related_synonym: 2-ammoniosuccinate
has_related_synonym: aspartic acid monoanion
id: CHEBI:35391
in subset: 3 STAR

cephalotaxine
type: Class
subclass of: secondary alcohol
subclass of: CHEBI_38164
subclass of: CHEBI_38523
subclass of: CHEBI_38527
subclass of: CHEBI_47985
subclass of: CHEBI_50996
subclass of: CHEBI_59770
definition: A benzazepine alkaloid isolated from Cephalotaxus harringtonia.
imported from: chebi.owl
charge: 0
formula: C18H21NO4
inchi: InChI=1S/C18H21NO4/c1-21-15-9-18-4-2-5-19(18)6-3-11-7-13-14(23-10-22-13)8-12(11)16(18)17(15)20/h7-9,16-17,20H,2-6,10H2,1H3/t16-,17-,18+/m1/s1
inchikey: YMNCVRSYJBNGLD-KURKYZTESA-N
mass: 315.36368
monoisotopicmass: 315.14706
database_cross_reference: Beilstein:628324
database_cross_reference: CAS:24316-19-6
database_cross_reference: KEGG:C10580
database_cross_reference: KNApSAcK:C00002324
database_cross_reference: KNApSAcK:C00027319
database_cross_reference: Reaxys:628324
has exact synonym: Cephalotaxine
has exact synonym: cephalotaxine
has_obo_namespace: chebi_ontology
has_related_synonym: (-)-Cephalotaxine
has_related_synonym: (1S,3aR,14bS)-2-methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol
id: CHEBI:3540
in subset: 3 STAR

oxoanion
type: Class
subclass of: oxide
subclass of: polyatomic anion
definition: An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
imported from: chebi.owl
has_alternative_id: CHEBI:33274
has_alternative_id: CHEBI:33436
has exact synonym: oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: oxoacid anions
has_related_synonym: oxoanions
id: CHEBI:35406
in subset: 3 STAR

alpha-amino-acid residue cation
type: Class
subclass of: CHEBI_64769
definition: Any alpha-amino-acid residue that is positively charged.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino-acid residue cations
id: CHEBI:35415
in subset: 3 STAR

alpha-amino-acid residue anion
type: Class
subclass of: CHEBI_64898
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: alpha-amino-acid residue anions
id: CHEBI:35416
in subset: 3 STAR

ortho-fused polycyclic hydrocarbon
type: Class
subclass of: ortho-fused compound
imported from: chebi.owl
has exact synonym: ortho-fused polycyclic hydrocarbon
has_obo_namespace: chebi_ontology
has_related_synonym: ortho-fused polycyclic hydrocarbons
id: CHEBI:35427
in subset: 3 STAR

antiinfective agent
type: Class
subclass of: drug
definition: A substance used in the prophylaxis or therapy of infectious diseases.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: anti-infective agents
has_related_synonym: anti-infective drugs
has_related_synonym: antiinfective agents
has_related_synonym: antiinfective drug
id: CHEBI:35441
in subset: 3 STAR

antiparasitic agent
type: Class
subclass of: antiinfective agent
definition: A substance used to treat or prevent parasitic infections.
imported from: chebi.owl
database_cross_reference: Wikipedia:Antiparasitic
has_obo_namespace: chebi_ontology
has_related_synonym: antiparasitic drugs
has_related_synonym: antiparasitics
has_related_synonym: parasiticides
id: CHEBI:35442
in subset: 3 STAR

anthelminthic drug
type: Class
subclass of: antiparasitic agent
definition: Substance intended to kill parasitic worms (helminths).
imported from: chebi.owl
has exact synonym: anthelminthic
has_obo_namespace: chebi_ontology
has_related_synonym: anthelminthics
has_related_synonym: anthelmintic
has_related_synonym: anthelmintics
has_related_synonym: antihelminth
has_related_synonym: antihelmintico
has_related_synonym: vermifuge
id: CHEBI:35443
in subset: 3 STAR

antinematodal drug
type: Class
subclass of: nematicide
subclass of: anthelminthic drug
definition: A substance used in the treatment or control of nematode infestations.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antinematodal agent
has_related_synonym: antinematodal drugs
has_related_synonym: antinematodals
id: CHEBI:35444
in subset: 3 STAR

EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
type: Class
subclass of: antihypertensive agent
subclass of: CHEBI_76782
definition: An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
imported from: chebi.owl
database_cross_reference: Wikipedia:ACE_inhibitor
has_obo_namespace: chebi_ontology
has_related_synonym: ACE inhibitor
has_related_synonym: ACE inhibitors
has_related_synonym: DCP inhibitor
has_related_synonym: DCP inhibitors
has_related_synonym: EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitors
has_related_synonym: EC 3.4.15.1 inhibitor
has_related_synonym: EC 3.4.15.1 inhibitors
has_related_synonym: PDH inhibitor
has_related_synonym: PDH inhibitors
has_related_synonym: angiotensin I-converting enzyme inhibitor
has_related_synonym: angiotensin I-converting enzyme inhibitors
has_related_synonym: angiotensin-converting enzyme inhibitor
has_related_synonym: angiotensin-converting enzyme inhibitors
has_related_synonym: carboxycathepsin inhibitor
has_related_synonym: carboxycathepsin inhibitors
has_related_synonym: dipeptidase inhibitor
has_related_synonym: dipeptidase inhibitors
has_related_synonym: dipeptide hydrolase inhibitor
has_related_synonym: dipeptide hydrolase inhibitors
has_related_synonym: dipeptidyl carboxypeptidase I inhibitor
has_related_synonym: dipeptidyl carboxypeptidase I inhibitors
has_related_synonym: dipeptidyl carboxypeptidase inhibitor
has_related_synonym: dipeptidyl carboxypeptidase inhibitors
has_related_synonym: endothelial cell peptidyl dipeptidase inhibitor
has_related_synonym: endothelial cell peptidyl dipeptidase inhibitors
has_related_synonym: kininase II inhibitor
has_related_synonym: kininase II inhibitors
has_related_synonym: peptidase P inhibitor
has_related_synonym: peptidase P inhibitors
has_related_synonym: peptidyl dipeptidase A inhibitor
has_related_synonym: peptidyl dipeptidase A inhibitors
has_related_synonym: peptidyl dipeptidase I inhibitor
has_related_synonym: peptidyl dipeptidase I inhibitors
has_related_synonym: peptidyl dipeptidase-4 inhibitor
has_related_synonym: peptidyl dipeptidase-4 inhibitors
has_related_synonym: peptidyl dipeptide hydrolase inhibitor
has_related_synonym: peptidyl dipeptide hydrolase inhibitors
has_related_synonym: peptidyl-dipeptidase A (EC 3.4.15.1) inhibitor
has_related_synonym: peptidyl-dipeptidase A (EC 3.4.15.1) inhibitors
has_related_synonym: peptidyl-dipeptidase A inhibitor
has_related_synonym: peptidyl-dipeptidase A inhibitors
has_related_synonym: peptidyl-dipeptide hydrolase inhibitor
has_related_synonym: peptidyl-dipeptide hydrolase inhibitors
has_related_synonym: peptidyldipeptide hydrolase inhibitor
has_related_synonym: peptidyldipeptide hydrolase inhibitors
id: CHEBI:35457
in subset: 3 STAR

cepharanthine
type: Class
subclass of: bisbenzylisoquinoline alkaloid
subclass of: isoquinolines
subclass of: Restriction
  on property: chemical inhibits in vitro replication of virus
  some values from: NCBITaxon_694009
subclass of: Restriction
  on property: chemical modulates response in vitro against virus
  some values from: NCBITaxon_694009
definition: A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation.
definition source: PMID: 32366720; PMID: 31690059
imported from: chebi.owl
charge: 0
formula: C37H38N2O6
inchi: InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1
inchikey: YVPXVXANRNDGTA-WDYNHAJCSA-N
mass: 606.709
monoisotopicmass: 606.27299
database_cross_reference: Beilstein:75231
database_cross_reference: CAS:481-49-2
database_cross_reference: KEGG:C09391
database_cross_reference: KEGG:D01035
database_cross_reference: KNApSAcK:C00001836
database_cross_reference: PMID:26703475
database_cross_reference: Reaxys:75231
has exact synonym: (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2(16,19).1(3,10).1(21,25).0(4,8).0(14,39).0(31,35)]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene
has exact synonym: Cepharanthine
has_obo_namespace: chebi_ontology
has_related_synonym: (+)-Cepharanthine
has_related_synonym: 6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))oxyacanthan
id: CHEBI:3546
in subset: 3 STAR

antidepressant
type: Class
subclass of: psychotropic drug
definition: Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antidepressant drugs
has_related_synonym: antidepressants
has_related_synonym: thymoanaleptics
has_related_synonym: thymoleptic drugs
has_related_synonym: thymoleptics
id: CHEBI:35469
in subset: 3 STAR

central nervous system drug
type: Class
subclass of: drug
definition: A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: CNS agent
has_related_synonym: CNS drugs
has_related_synonym: central nervous system agents
id: CHEBI:35470
in subset: 3 STAR

psychotropic drug
type: Class
subclass of: central nervous system drug
definition: A loosely defined grouping of drugs that have effects on psychological function.
imported from: chebi.owl
database_cross_reference: Wikipedia:Psychotropic_drug
has_obo_namespace: chebi_ontology
has_related_synonym: psychoactive agent
has_related_synonym: psychoactive drugs
has_related_synonym: psychopharmaceuticals
has_related_synonym: psychotropic drugs
id: CHEBI:35471
in subset: 3 STAR

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: CHEBI_67079
definition: A substance that reduces or suppresses inflammation.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: anti-inflammatory drugs
has_related_synonym: antiinflammatory agent
has_related_synonym: antiinflammatory drug
has_related_synonym: antiinflammatory drugs
id: CHEBI:35472
in subset: 3 STAR

tranquilizing drug
type: Class
subclass of: psychotropic drug
subclass of: central nervous system depressant
definition: A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ataractics
has_related_synonym: tranquilising drug
has_related_synonym: tranquilizing drugs
has_related_synonym: tranquillising agent
has_related_synonym: tranquillizing agents
id: CHEBI:35473
in subset: 3 STAR

non-steroidal anti-inflammatory drug
type: Class
subclass of: anti-inflammatory drug
subclass of: CHEBI_35842
definition: An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
imported from: chebi.owl
database_cross_reference: Wikipedia:Non-steroidal_anti-inflammatory_drug
has_obo_namespace: chebi_ontology
has_related_synonym: NSAID
has_related_synonym: NSAIDs
has_related_synonym: non-steroidal anti-inflammatory agent
has_related_synonym: non-steroidal anti-inflammatory drugs
id: CHEBI:35475
in subset: 3 STAR

antipsychotic agent
type: Class
subclass of: tranquilizing drug
definition: Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Neuroleptikum
has_related_synonym: antipsychotic agents
has_related_synonym: antipsychotic drug
has_related_synonym: antipsychotic drugs
has_related_synonym: antipsychotics
has_related_synonym: antipsychotiques
has_related_synonym: grosser Tranquilizer
has_related_synonym: major tranquilizers
has_related_synonym: major tranquilizing agents
has_related_synonym: neuroleptic
has_related_synonym: neuroleptic agents
has_related_synonym: neuroleptics
has_related_synonym: neuroleptique
has_related_synonym: neuroleptiques
id: CHEBI:35476
in subset: 3 STAR

antimanic drug
type: Class
subclass of: tranquilizing drug
definition: Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antimanic agent
has_related_synonym: antimanic drugs
has_related_synonym: antimanics
id: CHEBI:35477
in subset: 3 STAR

analgesic
type: Class
subclass of: drug
subclass of: CHEBI_52210
definition: An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:35480
in subset: 3 STAR

non-narcotic analgesic
type: Class
subclass of: analgesic
definition: A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:35481
in subset: 3 STAR

opioid analgesic
type: Class
subclass of: analgesic
definition: A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: narcotic
has_related_synonym: narcotic analgesic
has_related_synonym: narcotic analgesics
has_related_synonym: narcotics
has_related_synonym: opioid analgesics
id: CHEBI:35482
in subset: 3 STAR

central nervous system depressant
type: Class
subclass of: central nervous system drug
definition: A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: CNS depressants
has_related_synonym: central nervous system depressants
id: CHEBI:35488
in subset: 3 STAR

antipyretic
type: Class
subclass of: drug
definition: A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
imported from: chebi.owl
database_cross_reference: Wikipedia:Antipyretic
has_obo_namespace: chebi_ontology
has_related_synonym: anti-pyretic
id: CHEBI:35493
in subset: 3 STAR

fluorobenzenes
type: Class
subclass of: benzenes
subclass of: CHEBI_37143
definition: Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:35496
in subset: 3 STAR

addition compound
type: Class
subclass of: CHEBI_37577
definition: An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: addition compounds
id: CHEBI:35504
in subset: 3 STAR

hydrate
type: Class
subclass of: addition compound
subclass of: Restriction
  on property: has part
  some values from: water
definition: An addition compound that contains water in weak chemical combination with another compound.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Hydrat
has_related_synonym: hidrato
has_related_synonym: hidratos
has_related_synonym: hydrates
id: CHEBI:35505
in subset: 3 STAR

alkaloid fundamental parent
type: Class
subclass of: natural product fundamental parent
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: alkaloid fundamental parents
id: CHEBI:35506
in subset: 3 STAR

natural product fundamental parent
type: Class
subclass of: organic fundamental parent
imported from: chebi.owl
has exact synonym: natural product fundamental parents
has_obo_namespace: chebi_ontology
id: CHEBI:35507
in subset: 3 STAR

steroid fundamental parent
type: Class
subclass of: steroid
subclass of: natural product fundamental parent
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: steroid fundamental parents
id: CHEBI:35508
in subset: 3 STAR

hypoglycemic agent
type: Class
subclass of: drug
definition: A drug which lowers the blood glucose level.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: antidiabetic
has_related_synonym: antihyperglycemic
has_related_synonym: antihyperglycemic agent
has_related_synonym: antihyperglycemic agents
has_related_synonym: antihyperglycemic drug
has_related_synonym: antihyperglycemic drugs
has_related_synonym: antihyperglycemics
has_related_synonym: hypoglycemic agents
has_related_synonym: hypoglycemic drug
has_related_synonym: hypoglycemic drugs
id: CHEBI:35526
in subset: 3 STAR

5beta-cardanolide
type: Class
subclass of: cardanolide
imported from: chebi.owl
charge: 0
formula: C23H36O2
inchi: InChI=1S/C23H36O2/c1-22-11-4-3-5-16(22)6-7-17-19-9-8-18(15-13-21(24)25-14-15)23(19,2)12-10-20(17)22/h15-20H,3-14H2,1-2H3/t15-,16-,17-,18+,19+,20-,22-,23+/m0/s1
inchikey: AQARKTASOBROAE-KPSWSRIPSA-N
mass: 344.53074
monoisotopicmass: 344.27153
has exact synonym: 5beta-cardanolide
has_obo_namespace: chebi_ontology
id: CHEBI:35542
in subset: 3 STAR

cardanolide
type: Class
subclass of: steroid lactone
subclass of: steroid fundamental parent
imported from: chebi.owl
charge: 0
formula: C23H36O2
inchi: InChI=1S/C23H36O2/c1-22-11-4-3-5-16(22)6-7-17-19-9-8-18(15-13-21(24)25-14-15)23(19,2)12-10-20(17)22/h15-20H,3-14H2,1-2H3/t15-,16?,17-,18+,19+,20-,22-,23+/m0/s1
inchikey: AQARKTASOBROAE-OCYOQFCJSA-N
mass: 344.53074
monoisotopicmass: 344.27153
has exact synonym: cardanolide
has_obo_namespace: chebi_ontology
id: CHEBI:35543
in subset: 3 STAR

EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
type: Class
subclass of: CHEBI_76840
definition: A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor
has_related_synonym: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors
has_related_synonym: (PG)H synthase inhibitor
has_related_synonym: (PG)H synthase inhibitors
has_related_synonym: COX inhibitor
has_related_synonym: EC 1.14.99.1 (cyclooxygenase) inhibitor
has_related_synonym: EC 1.14.99.1 (cyclooxygenase) inhibitors
has_related_synonym: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors
has_related_synonym: EC 1.14.99.1 inhibitor
has_related_synonym: EC 1.14.99.1 inhibitors
has_related_synonym: PG synthetase inhibitor
has_related_synonym: PG synthetase inhibitors
has_related_synonym: cyclooxygenase (EC 1.14.99.1) inhibitor
has_related_synonym: cyclooxygenase (EC 1.14.99.1) inhibitors
has_related_synonym: cyclooxygenase inhibitor
has_related_synonym: cyclooxygenase inhibitors
has_related_synonym: fatty acid cyclooxygenase inhibitor
has_related_synonym: fatty acid cyclooxygenase inhibitors
has_related_synonym: prostaglandin G/H synthase inhibitor
has_related_synonym: prostaglandin G/H synthase inhibitors
has_related_synonym: prostaglandin endoperoxide synthetase inhibitor
has_related_synonym: prostaglandin endoperoxide synthetase inhibitors
has_related_synonym: prostaglandin synthase inhibitor
has_related_synonym: prostaglandin synthase inhibitors
has_related_synonym: prostaglandin synthetase inhibitor
has_related_synonym: prostaglandin synthetase inhibitors
id: CHEBI:35544
in subset: 3 STAR

heterocyclic organic fundamental parent
type: Class
subclass of: organic fundamental parent
imported from: chebi.owl
has exact synonym: heterocyclic parent hydrides
has_obo_namespace: chebi_ontology
has_related_synonym: heterocyclic fundamental parent
has_related_synonym: heterocyclic organic fundamental parents
has_related_synonym: organic heterocyclic fundamental parents
id: CHEBI:35552
in subset: 3 STAR

cardiovascular drug
type: Class
subclass of: drug
definition: A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: cardiovascular agent
has_related_synonym: cardiovascular drugs
id: CHEBI:35554
in subset: 3 STAR

mancude ring
type: Class
subclass of: molecular entity
definition: Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds.
imported from: chebi.owl
has exact synonym: mancude-ring systems
has_obo_namespace: chebi_ontology
has_related_synonym: mancude rings
has_related_synonym: mancunide-ring systems
id: CHEBI:35568
in subset: 3 STAR

mancude organic heterobicyclic parent
type: Class
subclass of: organic heterobicyclic compound
subclass of: mancude organic heterocyclic parent
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: mancude organic heterobicyclic parents
has_related_synonym: mancude-ring organic heterobicyclic parents
id: CHEBI:35570
in subset: 3 STAR

mancude organic heterocyclic parent
type: Class
subclass of: heterocyclic organic fundamental parent
subclass of: organic mancude parent
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: mancude organic heterocyclic parents
has_related_synonym: mancude-ring organic heterocyclic parents
id: CHEBI:35571
in subset: 3 STAR

organic mancude parent
type: Class
subclass of: organic fundamental parent
subclass of: mancude ring
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: organic mancude parents
has_related_synonym: organic mancude-ring parents
id: CHEBI:35573
in subset: 3 STAR

N-oxide
type: Class
subclass of: oxide
imported from: chebi.owl
has exact synonym: N-oxide
has_obo_namespace: chebi_ontology
has_related_synonym: N-oxides
id: CHEBI:35580
in subset: 3 STAR

purine
type: Class
subclass of: purines
subclass of: mancude organic heterobicyclic parent
subclass of: Restriction
  on property: has role
  some values from: CHEBI_78675
definition: A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines.
imported from: chebi.owl
charge: 0
formula: C5H4N4
mass: 120.112
monoisotopicmass: 120.04360
database_cross_reference: HMDB:HMDB0001366
database_cross_reference: KEGG:C15587
database_cross_reference: MetaCyc:PURINE
database_cross_reference: PMID:12865945
database_cross_reference: PMID:24088627
has exact synonym: purine
has_obo_namespace: chebi_ontology
id: CHEBI:35584
in subset: 3 STAR

1H-purine
type: Class
subclass of: purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 7H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 3H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 9H-purine
definition: The 1H-tautomer of purine.
imported from: chebi.owl
charge: 0
formula: C5H4N4
inchi: InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
inchikey: KDCGOANMDULRCW-UHFFFAOYSA-N
mass: 120.11210
monoisotopicmass: 120.04360
smiles: c1nc2c[nH]cnc2n1
database_cross_reference: Gmelin:2379911
has exact synonym: 1H-purine
has_obo_namespace: chebi_ontology
id: CHEBI:35586
in subset: 3 STAR

3H-purine
type: Class
subclass of: purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 7H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 1H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 9H-purine
definition: The 3H-tautomer of purine.
imported from: chebi.owl
charge: 0
formula: C5H4N4
inchi: InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
inchikey: KDCGOANMDULRCW-UHFFFAOYSA-N
mass: 120.11222
monoisotopicmass: 120.04360
smiles: c1nc2cnc[nH]c2n1
database_cross_reference: PMID:6149478
database_cross_reference: PMID:7178185
database_cross_reference: PMID:7296170
database_cross_reference: Reaxys:1210196
has exact synonym: 3H-purine
has_obo_namespace: chebi_ontology
id: CHEBI:35588
in subset: 3 STAR

9H-purine
type: Class
subclass of: purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 7H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 1H-purine
subclass of: Restriction
  on property: is tautomer of
  some values from: 3H-purine
definition: The 9H-tautomer of purine.
imported from: chebi.owl
charge: 0
formula: C5H4N4
inchi: InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
inchikey: KDCGOANMDULRCW-UHFFFAOYSA-N
mass: 120.11222
monoisotopicmass: 120.04360
smiles: c1ncc2nc[nH]c2n1
database_cross_reference: Beilstein:606899
database_cross_reference: CAS:120-73-0
database_cross_reference: Gmelin:3120
database_cross_reference: Wikipedia:Purine
has exact synonym: 9H-purine
has_obo_namespace: chebi_ontology
id: CHEBI:35589
in subset: 3 STAR

carbon oxoanion
type: Class
subclass of: organic anion
subclass of: oxoanion
subclass of: CHEBI_36963
definition: A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.
imported from: chebi.owl
has exact synonym: carbon oxoanion
has_obo_namespace: chebi_ontology
has_related_synonym: carbon oxoanions
has_related_synonym: oxocarbon anion
has_related_synonym: oxocarbon anions
id: CHEBI:35604
in subset: 3 STAR

carbon oxoacid
type: Class
subclass of: oxoacid
subclass of: CHEBI_36963
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: carbon oxoacids
has_related_synonym: oxoacids of carbon
id: CHEBI:35605
in subset: 3 STAR

antineoplastic agent
type: Class
subclass of: drug
definition: A substance that inhibits or prevents the proliferation of neoplasms.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: anticancer agent
has_related_synonym: anticancer agents
has_related_synonym: antineoplastic
has_related_synonym: antineoplastic agents
has_related_synonym: cytostatic
id: CHEBI:35610
in subset: 3 STAR

aromatic ether
type: Class
subclass of: ether
subclass of: organic aromatic compound
definition: Any ether in which the oxygen is attached to at least one aryl substituent.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
id: CHEBI:35618
in subset: 3 STAR

vasodilator agent
type: Class
subclass of: cardiovascular drug
definition: A drug used to cause dilation of the blood vessels.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: vasodilator
has_related_synonym: vasodilator agents
id: CHEBI:35620
in subset: 3 STAR

thiazolidines
type: Class
subclass of: organic heteromonocyclic compound
subclass of: CHEBI_38101
subclass of: CHEBI_38106
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: thiazolidine
id: CHEBI:35622
in subset: 3 STAR

anticonvulsant
type: Class
subclass of: central nervous system depressant
definition: A drug used to prevent seizures or reduce their severity.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: Antiepileptika
has_related_synonym: Antiepileptikum
has_related_synonym: Antikonvulsiva
has_related_synonym: Antikonvulsivum
has_related_synonym: anti-convulsant
has_related_synonym: anti-convulsants
has_related_synonym: anti-convulsive agent
has_related_synonym: anti-convulsive agents
has_related_synonym: anticonvulsants
has_related_synonym: anticonvulsive agent
has_related_synonym: anticonvulsive agents
has_related_synonym: antiepileptic
has_related_synonym: antiepileptics
has_related_synonym: antiepileptique
has_related_synonym: antiepileptiques
id: CHEBI:35623
in subset: 3 STAR

18-oxayohimban
type: Class
subclass of: CHEBI_38482
subclass of: CHEBI_38958
subclass of: Restriction
  on property: chemical has protein target as antagonist
  some values from: PR_000011650
subclass of: Restriction
  on property: has role
  some values from: CHEBI_48706
definition source: Reference: PMID: 9144641
imported from: chebi.owl
charge: 0
formula: C18H22N2O
inchi: InChI=1S/C18H22N2O/c1-2-4-16-14(3-1)15-5-7-20-10-13-11-21-8-6-12(13)9-17(20)18(15)19-16/h1-4,12-13,17,19H,5-11H2/t12-,13+,17-/m0/s1
inchikey: GAGIJETXYAHUIP-AHIWAGSCSA-N
mass: 282.38016
monoisotopicmass: 282.17321
has exact synonym: 18-oxayohimban
has_obo_namespace: chebi_ontology
has_related_synonym: (4aR,13bS,14aR)-1,2,4a,5,7,8,13,13b,14,14a-decahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine
has_related_synonym: oxayohimban
id: CHEBI:35638
in subset: 3 STAR

adrenergic uptake inhibitor
type: Class
subclass of: CHEBI_37962
definition: Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: ARI
has_related_synonym: NERI
has_related_synonym: NRI
has_related_synonym: adrenergic reuptake inhibitor
has_related_synonym: adrenergic reuptake inhibitors
has_related_synonym: adrenergic uptake inhibitors
has_related_synonym: norepinephrine reuptake inhibitor
has_related_synonym: norepinephrine reuptake inhibitors
id: CHEBI:35640
in subset: 3 STAR

galanthan
type: Class
subclass of: CHEBI_38511
subclass of: CHEBI_38513
imported from: chebi.owl
charge: 0
formula: C15H19N
inchi: InChI=1S/C15H19N/c1-2-6-13-12(4-1)10-16-9-8-11-5-3-7-14(13)15(11)16/h1-2,4,6,11,14-15H,3,5,7-10H2/t11-,14-,15+/m0/s1
inchikey: CDIONMUWHFYLPO-TUKIKUTGSA-N
mass: 213.31810
monoisotopicmass: 213.15175
database_cross_reference: Beilstein:8326915
has exact synonym: galanthan
has_obo_namespace: chebi_ontology
id: CHEBI:35646
in subset: 3 STAR

conanine
type: Class
subclass of: steroid
subclass of: CHEBI_38516
imported from: chebi.owl
charge: 0
formula: C22H37N
inchi: InChI=1S/C22H37N/c1-15-18-9-10-20-17-8-7-16-6-4-5-12-21(16,2)19(17)11-13-22(18,20)14-23(15)3/h15-20H,4-14H2,1-3H3/t15-,16?,17+,18+,19-,20-,21-,22-/m0/s1
inchikey: ICKQFGPZAUSMPE-PFKVMXGZSA-N
mass: 315.53592
monoisotopicmass: 315.29260
has exact synonym: conanine
has_obo_namespace: chebi_ontology
id: CHEBI:35655
in subset: 3 STAR

HIV protease inhibitor
type: Class
subclass of: CHEBI_37670
subclass of: CHEBI_64946
definition: An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
imported from: chebi.owl
database_cross_reference: Wikipedia:Protease_inhibitor_(pharmacology)
has_obo_namespace: chebi_ontology
has_related_synonym: HIV protease inhibitors
id: CHEBI:35660
in subset: 3 STAR

EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
type: Class
subclass of: CHEBI_76835
definition: Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
imported from: chebi.owl
database_cross_reference: PMID:1464741
database_cross_reference: PMID:15531285
database_cross_reference: PMID:20467214
database_cross_reference: Wikipedia:HMG-CoA_reductase
has_obo_namespace: chebi_ontology
has_related_synonym: HMG-CoA reductase inhibitor
has_related_synonym: HMG-CoA reductase inhibitors
has_related_synonym: hydroxymethylglutaryl-CoA reductase inhibitor
has_related_synonym: hydroxymethylglutaryl-CoA reductase inhibitors
id: CHEBI:35664
in subset: 3 STAR

antihypertensive agent
type: Class
subclass of: cardiovascular drug
definition: Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
imported from: chebi.owl
database_cross_reference: Wikipedia:Antihypertensive_drug
has_obo_namespace: chebi_ontology
has_related_synonym: antihypertensive
has_related_synonym: antihypertensive agents
has_related_synonym: antihypertensive drug
has_related_synonym: antihypertensive drugs
id: CHEBI:35674
in subset: 3 STAR

benzazepine
type: Class
subclass of: organic heterobicyclic compound
subclass of: CHEBI_38101
definition: A group of two-ring heterocyclic compounds consisting of a benzene ring fused to an azepine ring.
imported from: chebi.owl
has exact synonym: benzazepine
has_obo_namespace: chebi_ontology
has_related_synonym: benzazepines
has_related_synonym: benzoazepines
id: CHEBI:35676
in subset: 3 STAR

antilipemic drug
type: Class
subclass of: drug
definition: A substance used to treat hyperlipidemia (an excess of lipids in the blood).
imported from: chebi.owl
database_cross_reference: Wikipedia:Hypolipidemic_agent
has_obo_namespace: chebi_ontology
has_related_synonym: antihyperlipemic
has_related_synonym: antihyperlipemics
has_related_synonym: antihyperlipidaemic agent
has_related_synonym: antihyperlipidaemic agents
has_related_synonym: antihyperlipidaemic drug
has_related_synonym: antihyperlipidaemic drugs
has_related_synonym: antihyperlipidemic
has_related_synonym: antihyperlipidemic agent
has_related_synonym: antihyperlipidemic agents
has_related_synonym: antihyperlipidemic drug
has_related_synonym: antihyperlipidemic drugs
has_related_synonym: antihyperlipidemics
has_related_synonym: antilipemic
has_related_synonym: antilipemic drugs
has_related_synonym: antilipemics
has_related_synonym: hypolipidemic agent
has_related_synonym: hypolipidemic agents
has_related_synonym: lipid-lowering agent
has_related_synonym: lipid-lowering agents
has_related_synonym: lipid-lowering drug
has_related_synonym: lipid-lowering drugs
id: CHEBI:35679
in subset: 3 STAR

secondary alcohol
type: Class
subclass of: alcohol
definition: A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it.
imported from: chebi.owl
charge: 0
formula: CH2OR2
mass: 30.026
monoisotopicmass: 30.01056
smiles: *C(*)O
has_alternative_id: CHEBI:13425
has_alternative_id: CHEBI:13686
has_alternative_id: CHEBI:26617
has_alternative_id: CHEBI:58662
has_alternative_id: CHEBI:8741
has_alternative_id: CHEBI:9077
database_cross_reference: KEGG:C00432
database_cross_reference: KEGG:C01612
has exact synonym: Secondary alcohol
has_obo_namespace: chebi_ontology
has_related_synonym: R-CHOH-R'
has_related_synonym: a secondary alcohol
has_related_synonym: secondary alcohols
id: CHEBI:35681
in subset: 3 STAR

aryl sulfide
type: Class
subclass of: organic sulfide
definition: Any organic sulfide in which the sulfur is attached to at least one aromatic group.
imported from: chebi.owl
has exact synonym: aryl sulfide
has_obo_namespace: chebi_ontology
has_related_synonym: aryl sulfides
id: CHEBI:35683
in subset: 3 STAR

dicarboxylic acid
type: Class
subclass of: dicarboxylic acids and O-substituted derivatives
subclass of: carboxylic acid
subclass of: Restriction
  on property: is conjugate acid of
  some values from: dicarboxylic acid anion
definition: Any carboxylic acid containing two carboxy groups.
imported from: chebi.owl
has_alternative_id: CHEBI:23692
has_alternative_id: CHEBI:36172
has_alternative_id: CHEBI:4501
database_cross_reference: KEGG:C02028
has exact synonym: Dicarboxylic acid
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acids
id: CHEBI:35692
in subset: 3 STAR

dicarboxylic acid anion
type: Class
subclass of: carboxylic acid anion
subclass of: Restriction
  on property: is conjugate base of
  some values from: dicarboxylic acid
imported from: chebi.owl
has exact synonym: dicarboxylic acid anion
has_obo_namespace: chebi_ontology
has_related_synonym: dicarboxylic acid anions
id: CHEBI:35693
in subset: 3 STAR

ester
type: Class
subclass of: CHEBI_36963
subclass of: CHEBI_50860
definition: A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter.
imported from: chebi.owl
imported from: dron.owl
has_alternative_id: CHEBI:23960
has_alternative_id: CHEBI:4859
database_cross_reference: KEGG COMPOUND:C00287
database_cross_reference: KEGG:C00287
database_cross_reference: Wikipedia:Ester
has exact synonym: Ester
has_obo_namespace: chebi_ontology
has_related_synonym: esters
id: CHEBI:35701
in subset: 3 STAR

xenobiotic
type: Class
subclass of: biological role
definition: A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
imported from: chebi.owl
has_alternative_id: CHEBI:10074
has_alternative_id: CHEBI:27333
database_cross_reference: KEGG:C06708
database_cross_reference: Wikipedia:Xenobiotic
has exact synonym: Xenobiotic
has exact synonym: xenobiotic
has exact synonym: xenobiotics
has_obo_namespace: chebi_ontology
has_related_synonym: xenobiotic compounds
id: CHEBI:35703
in subset: 3 STAR

immunosuppressive agent
type: Class
subclass of: CHEBI_50846
definition: An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
imported from: chebi.owl
has_obo_namespace: chebi_ontology
has_related_synonym: immunosuppressant
has_related_synonym: immunosuppressive agents
has_related_synonym: inmunosupresor
id: CHEBI:35705
in subset: 3 STAR

nitro compound
type: Class
subclass of: CHEBI_51143
subclass of: Restriction
  on property: has part
  some values from: nitro group
definition: A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied).
imported from: chebi.owl
has exact synonym: nitro compounds
has_obo_namespace: chebi_ontology
id: CHEBI:35715
in subset: 3 STAR

C-nitro compound
type: Class
subclass of: nitro compound
subclass of: CHEBI_72695
definition: A nitro compound having the nitro group (-NO2) attached to a carbon atom.
imported from: chebi.owl
has exact synonym: C-nitro compounds
has_obo_namespace: chebi_ontology
id: CHEBI:35716
in subset: 3 STAR