2016-05-04 Jiangan Xie OWL-DL Stephan Schurer 2.1.80 Asiyah Yu Lin Edison Ong LINCS-CLOview LINCS-CLOview: A subset of the Cell Line Ontology (CLO) that represents all known cell lines using in the NIH Library of Integrated Network-based Cellular Signatures (LINCS) project. Qingping Liu Yongqun "Oliver" He (YH) Zhaohui Ni Description Description An account of the content of the resource. Contributor Contributor database_cross_reference database_cross_reference curator notes curator notes curator note curator note 1 IAO:0000232 curator_notes curator_notes uberon An administrative note of use for a curator but of no use for a user PERSON:Alan Ruttenberg curator note depicted_by depicted_by 1 foaf-depicted_by foaf-depicted_by uberon has_obo_namespace has_obo_namespace BFO OWL specification label BFO OWL specification label BFO OWL specification label Really of interest to developers only Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. Creator Creator structure_notes structure_notes 1 Notes on the structure, composition or histology of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000010 structure_notes structure_notes uberon dubious_for_taxon dubious_for_taxon 1 1 RO:0002174 S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T. dubious_for_taxon dubious_for_taxon this relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take time to resolve. Example: metencephalon in teleost uberon Subject and Keywords Subject and Keywords The topic of the content of the resource. external_ontology_notes external_ontology_notes 1 Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 external_ontology_notes external_ontology_notes uberon development_notes development_notes 1 Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 development_notes development_notes uberon has_exact_synonym has_exact_synonym has associated axiom(nl) has associated axiom(nl) An axiom associated with a term expressed using natural language Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(nl) has associated axiom(fol) has associated axiom(fol) An axiom expressed in first order logic using CLIF syntax Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(fol) temporal interpretation temporal interpretation https://code.google.com/p/obo-relations/wiki/ROAndTime https://github.com/oborel/obo-relations/wiki/ROAndTime temporal interpretation elucidation elucidation Person:Barry Smith Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms elucidation person:Alan Ruttenberg Date Date has_narrow_synonym has_narrow_synonym Title Title A name given to the resource. has_broad_synonym has_broad_synonym external_definition external_definition 1 An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000001 external_definition external_definition uberon STR profile Yongqun He An annotation property that specifies an STR profile of a cell line cell. BFO CLIF specification label BFO CLIF specification label Person:Alan Ruttenberg BFO CLIF specification label Really of interest to developers only Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 fma_set_term fma_set_term 1 FMA has terms like 'set of X'. In general we do not include set-of terms in uberon, but provide a mapping between the singular form and the FMA set term UBPROP:0000202 fma_set_term fma_set_term uberon shorthand shorthand in_subset in_subset definition textual definition textual definition definition definition GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. definition definition editor note editor note editor note 1 IAO:0000116 editor_note editor_note uberon An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. GROUP:OBI:<http://purl.obfoundry.org/obo/obi> PERSON:Daniel Schober editor note has curation status has curation status OBI_0000281 PERSON:Alan Ruttenberg PERSON:Bill Bug PERSON:Melanie Courtot has curation status definition source definition source Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober definition source formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 term editor term editor 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115. GROUP:OBI:<http://purl.obolibrary.org/obo/obi> Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people PERSON:Daniel Schober term editor alternative term alternative term An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent) GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober alternative term has_alternative_id has_alternative_id taxon_notes taxon_notes 1 Notes on the how instances of this class vary across species. UBPROP:0000008 taxon_notes taxon_notes uberon function_notes function_notes 1 Notes on the evolved function of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000009 function_notes function_notes uberon Source Source implements_design_pattern implements_design_pattern 1 UBPROP:0000006 implements_design_pattern implements_design_pattern uberon has_relational_adjective has_relational_adjective 1 UBPROP:0000007 Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. has_relational_adjective has_relational_adjective uberon editor preferred term~editor preferred label editor preferred term editor preferred label editor preferred label editor preferred term editor preferred term~editor preferred label GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) editor preferred term example of usage example of usage A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober example example of usage axiom_lost_from_external_ontology axiom_lost_from_external_ontology 1 A textual description of an axiom loss in this ontology compared to an external ontology. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000002 axiom_lost_from_external_ontology axiom_lost_from_external_ontology uberon homology_notes homology_notes 1 Notes on the homology status of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000003 homology_notes homology_notes uberon label seeAlso has_related_synonym has_related_synonym imported from imported from For external terms/classes, the ontology from which the term was imported GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Alan Ruttenberg PERSON:Melanie Courtot imported from Cell line LINCS ID Cell line LINCS ID Oliver He, Jiangan Xie An annotation property that represents an LINCS ID of a cell line. Format Format The physical or digital manifestation of the resource. part_of has part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime a core relation that holds between a whole and its part has part has_part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) realizes Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process realizes this disease course realizes this disease this investigation realizes this investigator role this shattering realizes this fragility to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) located_in derives originally from patient having disease Yongqun He In most cases, the patient in the relation is used to refer human patient. However, an animal patient (or veterinary patient) can also be referred. has disease Jie Zheng, Yongqun He, Yu Lin, Allen Xiang is in cell line repository an object property that specifies a cell line repository for a specifc cell line. SS, YH, UV, SS is disease model for an object property that represents a relation between a cell line cell and a disease. Asiyah Yu Lin, Yongqun He This object property is largely equivalent to the previous term 'is model for' (http://www.ebi.ac.uk/cellline#is_model_for). is about Smith, Ceusters, Ruttenberg, 2000 years of philosophy This document is about information artifacts and their representations is about is_about is a (currently) primitive relation that relates an information artifact to an entity. person:Alan Ruttenberg has_specified_input 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works. PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Coutot A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_input see is_input_of example_of_usage is_specified_input_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Alan Ruttenberg is_specified_input_of some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay has_specified_output PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Courtot A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_output is_specified_output_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Alan Ruttenberg is_specified_output_of achieves_planned_objective A cell sorting process achieves the objective specification 'material separation objective' BP, AR, PPPB branch PPPB branch derived This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process. achieves_planned_objective modified according to email thread from 1/23/09 in accordince with DT and PPPB branch has grain PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349 has grain the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car. Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form PERSON: Alan Ruttenberg objective_achieved_by This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process. objective_achieved_by OBI OBI bearer of A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence bearer of bearer_of is bearer of this apple is bearer of this red color this vase is bearer of this fragility participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process participates in participates_in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation has participant Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. a relation between a process and a continuant, in which the continuant is somehow involved in the process has participant http://www.obofoundry.org/ro/#OBO_REL:has_participant has_participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) concretizes A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant). A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant. An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process). concretizes has role A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence has role has_role this person has role this investigator role (more colloquially: this person has this role of investigator) derives_from derives from This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'. a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives from derives_from this cell derives from this parent cell (cell division) this nucleus derives from this parent nucleus (nuclear division) derives into This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'. a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives into derives_into this parent cell derives into this cell (cell division) this parent nucleus derives into this nucleus (nuclear division) is model for has_disease_location gonad A reproductive system organ that produces and releases either sperm (testis) or eggs (ovary). Gonadal Gonads The part of the reproductive system that produces and releases eggs (ovaries) or sperm (testicles/testes).NCI-GLOSS UMLS: C0018067 URI: http://www.ebi.ac.uk/cellline#Organ entity An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) entity Entity BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf Julius Caesar Verdi’s Requiem entity the Second World War your body mass index continuant (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) Continuant continuant (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants continuant if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) occurrent Occurrent (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] occurrent (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] An entity that has temporal parts and that happens, unfolds or develops through time. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) occurrent independent continuant (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) ic IndependentContinuant a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) independent continuant the bottom right portion of a human torso the interior of your mouth process An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) process Process (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] a process of cell-division, \ a beating of the heart a process of meiosis a process of sleeping p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) process the course of a disease the flight of a bird the life of an organism your process of aging. disposition disposition Disposition (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) an atom of element X has the disposition to decay to an atom of element Y b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) certain people have a predisposition to colon cancer children are innately disposed to categorize objects in certain ways. disposition the cell wall is disposed to filter chemicals in endocytosis and exocytosis realizable entity (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] RealizableEntity realizable A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) realizable entity the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of being a doctor the role of this boundary to delineate where Utah and Colorado meet specifically dependent continuant (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] sdc (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. SpecificallyDependentContinuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. specifically dependent continuant the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella role role (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. Role b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) role the priest role the role of a boundary to demarcate two neighboring administrative territories the role of a building in serving as a military target the role of a stone in marking a property boundary the role of subject in a clinical trial the student role generically dependent continuant gdc GenericallyDependentContinuant (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) generically dependent continuant the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. material entity (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] material MaterialEntity (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) a flame a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) material entity the undetached arm of a human being cell line cell culturing YH a maintaining cell culture process that keeps cell line cell alive and actively cultured. cell line cell cell line cell A 'cell line cell' is a part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures. A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters suspension cell line culturing suspension cell line culturing is a cell line culturing method where cells do not require a surface for growth and differentiation. This method is appropriate for cells that are adapted to suspension culture or cells that are non-adhesive (e.g. hematopoietic cells) adherent cell line culturing adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation. cell line repository role a role that inheres in a cell line repository organization. SS, YH cell line repository an organization that serves as a repository of cell lines. SS, YH immortal human T cell line cell YH an immortal human lymphocyte cell line cell that is derived from T cell. adherent on feeder cells cell line culturing adherent-patchy cell line culturing loosely adherent cell line culturing immortal cell line cell immortal cell line cell permanent cell line cell A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line. Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak continuous cell line cell immortal human cell line cell YH a immortal cell line that is dervied from human tissue. immortal human cell line adherent cell culture growth mode YH a cell culture growth mode that indicates a cell needs to adhere to a cell culture plate to grow. suspension cell culture growth mode YH a cell culture growth mode that indicates a cell can grow when the cell is suspended in cell culture medium. cell culture growth mode YH a disposition that represents a mode of cell culture growth, i.e., the cell will grow at a specific cell culture mode. For example, an adherent cell culture growh mode means that the cell will grow when the cell is adhere to a cell culture plate. cell line MB, SS, JZ, MAH, BP, CS, YH A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). cell line mixed adherent and suspension cell line culturing mixed suspension clusters in suspension cell line culturing immortal mouse cell line cell Yue Liu, Yongqun He a immortal cell line that is dervied from mouse tissue. immortal mouse cell line immortal stem cell line cell ZX, YH a cell line that is derived from stem cell immortal somatic stem cell line cell ZX, YH a immortal stem cell line that is derived from somatic stem cell immortal multi fate stem cell line cell ZX, YH a immortal somatic stem cell line that is derived from multi fate stem cell immortal neuronal stem cell line cell ZX, YH a immortal multi fate stem cell line that is derived from neuronal stem cell immortal neuroblast cell line cell ZX, YH a immortal neuronal stem cell line that is derived from neuroblast immortal non-terminally differentiated cell line cell ZX, YH a cell line that is derived from non-terminally differentiated cell immortal non-terminally differentiated cell line immortal contractile cell line cell ZX, YH an immortal cell line cell that is derived from contractile cell immortal muscle cell line cell ZX, YH a immortal contractile cell line cell that is derived from muscle cell immortal electrically active cell line cell ZX, YH an immortal cell line cell that is derived from electrically active cell immortal electrically responsive cell line cell ZX, YH a immortal electrically active cell line cell that is derived from electrically responsive cell immortal neuron cell line cell ZX, YH a immortal electrically responsive cell line cell that is derived from neuron immortal bipolar neuron cell line cell ZX, YH a immortal neuron cell line cell that is derived from bipolar neuron immortal peripheral neuron cell line cell ZX, YH a immortal neuron cell line cell that is derived from peripheral neuron immortal motile cell line cell ZX, YH a cell line that is derived from motile cell immortal motile cell line immortal leukocyte cell line cell ZX, YH a immortal motile cell line that is derived from leukocyte immortal leukocyte cell line immortal myeloid leukocyte cell line cell ZX, YH a immortal leukocyte cell line that is derived from myeloid leukocyte immortal myeloid leukocyte cell line immortal monocyte cell line cell ZX, YH a immortal myeloid leukocyte cell line that is derived from monocyte immortal monocyte cell line immortal nongranular leukocyte cell line cell ZX, YH a immortal leukocyte cell line that is derived from nongranular leukocyte immortal nongranular leukocyte cell line immortal lymphocyte cell line cell ZX, YH a immortal nongranular leukocyte cell line that is derived from lymphocyte immortal lymphocyte cell line immortal B cell line cell ZX, YH a immortal lymphocyte cell line that is derived from B cell immortal B cell line immortal eukaryotic cell line cell ZX, YH a immortal cell line cell that is derived from eukaryotic cell immortal animal cell line cell ZX, YH a immortal eukaryotic cell line that is derived from animal cell immortal animal cell line immortal epithelial cell line cell ZX, YH a immortal animal cell line that is derived from epithelial cell immortal hematopoietic cell line cell ZX, YH a immortal animal cell line that is derived from hematopoietic cell immortal hematopoietic cell line immortal blood cell line cell ZX, YH a immortal hematopoietic cell line that is derived from blood cell immortal blood cell line immortal myeloid cell line cell ZX, YH a immortal hematopoietic cell line that is derived from myeloid cell immortal myeloid cell line immortal hematopoietic lineage restricted progenitor cell line cell ZX, YH a immortal hematopoietic cell line that is derived from hematopoietic lineage restricted progenitor cell immortal hematopoietic lineage restricted progenitor cell line immortal myeloblast cell line cell ZX, YH a immortal hematopoietic lineage restricted progenitor cell line that is derived from myeloblast immortal myeloblast cell line immortal neural cell line cell ZX, YH a immortal animal cell line that is derived from neural cell immortal neural cell line immortal connective tissue cell line cell ZX, YH a immortal animal cell line that is derived from connective tissue cell immortal fibroblast cell line cell ZX, YH a immortal connective tissue cell line that is derived from fibroblast immortal fibroblast cell line immortal nucleate cell line cell ZX, YH a cell line that is derived from nucleate cell immortal nucleate cell line immortal somatic cell line cell ZX, YH a cell line that is derived from somatic cell immortal animal ovary-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from animal ovary. Yue Liu, Yongqun He immortal skin-derived cell line cell An immortal cell line cell that derives from skin. Yue Liu, Yongqun He immortal spleen-derived cell line cell An immortal cell line cell that derives from spleen. Yue Liu, Yongqun He immortal mixed endoderm/mesoderm-derived structure-derived cell line cell An immortal cell line cell that derives from mixed endoderm/mesoderm-derived structure. Yue Liu, Yongqun He immortal tongue-derived cell line cell An immortal cell line cell that derives from tongue. Yue Liu, Yongqun He immortal lung-derived cell line cell An immortal cell line cell that derives from pair of lungs. Yue Liu, Yongqun He immortal kidney-derived cell line cell An immortal cell line cell that derives from kidney. Yue Liu, Yongqun He immortal placenta-derived cell line cell An immortal cell line cell that derives from placenta. Yue Liu, Yongqun He immortal embryo-derived cell line cell An immortal cell line cell that derives from embryo. Yue Liu, Yongqun He immortal prostate gland-derived cell line cell An immortal cell line cell that derives from prostate gland. Yue Liu, Yongqun He immortal somatic nervous system-derived cell line cell An immortal cell line cell that derives from somatic nervous system. Yue Liu, Yongqun He immortal liver-derived cell line cell An immortal cell line cell that derives from liver. Yue Liu, Yongqun He immortal colon-derived cell line cell An immortal cell line cell that derives from colon. Yue Liu, Yongqun He immortal caecum-derived cell line cell An immortal cell line cell that derives from caecum. Yue Liu, Yongqun He immortal pancreas-derived cell line cell An immortal cell line cell that derives from pancreas. Yue Liu, Yongqun He immortal brain-derived cell line cell An immortal cell line cell that derives from brain. Yue Liu, Yongqun He immortal female gonad-derived cell line cell An immortal cell line cell that derives from female gonad. Yue Liu, Yongqun He immortal testis-derived cell line cell An immortal cell line cell that derives from testis. Yue Liu, Yongqun He immortal stomach-derived cell line cell An immortal cell line cell that derives from stomach. Yue Liu, Yongqun He immortal bone element-derived cell line cell An immortal cell line cell that derives from bone element. Yue Liu, Yongqun He immortal thyroid gland-derived cell line cell An immortal cell line cell that derives from thyroid gland. Yue Liu, Yongqun He immortal urinary bladder-derived cell line cell An immortal cell line cell that derives from urinary bladder. Yue Liu, Yongqun He immortal acetabular part of hip bone-derived cell line cell An immortal cell line cell that derives from acetabular part of hip bone. Yue Liu, Yongqun He immortal breast-derived cell line cell An immortal cell line cell that derives from breast. Yue Liu, Yongqun He immortal comma-shaped body-derived cell line cell An immortal cell line cell that derives from comma-shaped body. Yue Liu, Yongqun He immortal supra-orbital vein-derived cell line cell An immortal cell line cell that derives from supra-orbital vein. Yue Liu, Yongqun He immortal uterus-derived cell line cell An immortal cell line cell that derives from uterus. Yue Liu, Yongqun He immortal endometrium-derived cell line cell An immortal cell line cell that derives from endometrium. Yue Liu, Yongqun He immortal uterine cervix-derived cell line cell An immortal cell line cell that derives from uterine cervix. Yue Liu, Yongqun He immortal follicular fluid-derived cell line cell An immortal cell line cell that derives from follicular fluid. Yue Liu, Yongqun He immortal mammary gland-derived cell line cell An immortal cell line cell that derives from mammary gland. Yue Liu, Yongqun He immortal bone marrow-derived cell line cell An immortal cell line cell that derives from bone marrow. Yue Liu, Yongqun He immortal uterine cervix-derived epithelial cell line cell An immortal epithelial cell line cell that derives from uterine cervix. Yue Liu, Yongqun He immortal ileocecal junction-derived cell line cell An immortal cell line cell that derives from ileocecal junction. Yue Liu, Yongqun He immortal vagina-derived cell line cell An immortal cell line cell that derives from vagina. Yue Liu, Yongqun He immortal larynx-derived cell line cell An immortal cell line cell that derives from larynx. Yue Liu, Yongqun He immortal esophagus-derived cell line cell An immortal cell line cell that derives from esophagus. Yue Liu, Yongqun He immortal gingiva-derived cell line cell An immortal cell line cell that derives from gingiva. Yue Liu, Yongqun He immortal mouth-derived cell line cell An immortal cell line cell that derives from mouth. Yue Liu, Yongqun He immortal round window-derived cell line cell An immortal cell line cell that derives from round window. Yue Liu, Yongqun He immortal intestine-derived cell line cell An immortal cell line cell that derives from intestine. Yue Liu, Yongqun He immortal rectum-derived cell line cell An immortal cell line cell that derives from rectum. Yue Liu, Yongqun He immortal tonsil-derived cell line cell An immortal cell line cell that derives from tonsil. Yue Liu, Yongqun He immortal adrenal gland-derived cell line cell An immortal cell line cell that derives from adrenal gland. Yue Liu, Yongqun He immortal ureter-derived cell line cell An immortal cell line cell that derives from ureter. Yue Liu, Yongqun He immortal cornea-derived cell line cell An immortal cell line cell that derives from cornea. Yue Liu, Yongqun He immortal mammalian vulva-derived cell line cell An immortal cell line cell that derives from mammalian vulva. Yue Liu, Yongqun He immortal spherical lensed eye-derived cell line cell An immortal cell line cell that derives from spherical lensed eye. Yue Liu, Yongqun He immortal cervix-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from cervix. Yue Liu, Yongqun He immortal chordate pharynx-derived cell line cell An immortal cell line cell that derives from chordate pharynx. Yue Liu, Yongqun He immortal pelvic fin-derived cell line cell An immortal cell line cell that derives from pelvic fin. Yue Liu, Yongqun He immortal right ureter-derived cell line cell An immortal cell line cell that derives from right ureter. Yue Liu, Yongqun He immortal human skin-derived cell line cell An immortal skin-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human lymphocyte cell line cell An immortal lymphocyte cell line cell that derives from human. Yue Liu, Yongqun He immortal human septum of telencephalon-derived cell line cell An immortal septum of telencephalon-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human mixed endoderm/mesoderm-derived structure-derived cell line cell An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human lung-derived cell line cell An immortal lung-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal mouse embryo-derived cell line cell An immortal embryo-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal human cell line cell An immortal cell line cell that derives from human. Yue Liu, Yongqun He immortal human colon-derived cell line cell An immortal colon-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human caecum-derived cell line cell An immortal caecum-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human brain-derived cell line cell An immortal brain-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal mouse skin-derived cell line cell An immortal skin-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal human peripheral neuron cell line cell An immortal peripheral neuron cell line cell that derives from human. Yue Liu, Yongqun He immortal human stomach-derived cell line cell An immortal stomach-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human pancreas-derived cell line cell An immortal pancreas-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human bone element-derived cell line cell An immortal bone element-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human epithelial cell line cell An immortal epithelial cell line cell that derives from human. Yue Liu, Yongqun He immortal human urinary bladder-derived cell line cell An immortal urinary bladder-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human liver-derived cell line cell An immortal liver-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human acetabular part of hip bone-derived cell line cell An immortal acetabular part of hip bone-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human comma-shaped body-derived cell line cell An immortal comma-shaped body-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human breast-derived cell line cell An immortal breast-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human spleen-derived cell line cell An immortal spleen-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human supra-orbital vein-derived cell line cell An immortal supra-orbital vein-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human uterus-derived cell line cell An immortal uterus-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human endometrium-derived cell line cell An immortal endometrium-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human kidney-derived cell line cell An immortal kidney-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human uterine cervix-derived cell line cell An immortal uterine cervix-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human follicular fluid-derived cell line cell An immortal follicular fluid-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human female gonad-derived cell line cell An immortal female gonad-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human thyroid gland-derived cell line cell An immortal thyroid gland-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human blood cell line cell An immortal blood cell line cell that derives from human. Yue Liu, Yongqun He immortal human uterine cervix-derived epithelial cell line cell An immortal uterine cervix-derived epithelial cell line cell that derives from human. Yue Liu, Yongqun He immortal human ileocecal junction-derived cell line cell An immortal ileocecal junction-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human B cell line cell An immortal B cell line cell that derives from human. Yue Liu, Yongqun He immortal human vagina-derived cell line cell An immortal vagina-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human larynx-derived cell line cell An immortal larynx-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human esophagus-derived cell line cell An immortal esophagus-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human gingiva-derived cell line cell An immortal gingiva-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human muscle cell line cell An immortal muscle cell line cell that derives from human. Yue Liu, Yongqun He immortal human mouth-derived cell line cell An immortal mouth-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human testis-derived cell line cell An immortal testis-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human intestine-derived cell line cell An immortal intestine-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human rectum-derived cell line cell An immortal rectum-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human tonsil-derived cell line cell An immortal tonsil-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human adrenal gland-derived cell line cell An immortal adrenal gland-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human placenta-derived cell line cell An immortal placenta-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human ovary-derived fibroblast cell line cell An immortal animal ovary-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human prostate gland-derived cell line cell An immortal prostate gland-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human ureter-derived cell line cell An immortal ureter-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human mammalian vulva-derived cell line cell An immortal mammalian vulva-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human spherical lensed eye-derived cell line cell An immortal spherical lensed eye-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human cervix-derived fibroblast cell line cell An immortal cervix-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human bone marrow-derived cell line cell An immortal bone marrow-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human chordate pharynx-derived cell line cell An immortal chordate pharynx-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human tongue-derived cell line cell An immortal tongue-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human neuroblast cell line cell An immortal neuroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human monocyte cell line cell An immortal monocyte cell line cell that derives from human. Yue Liu, Yongqun He 697 cell CVCL: CVCL_0079 CHEMBL: CHEMBL3308147 697 LCL-1042 disease: leukemia, pre-B cell HyperCLDB: cl117 Sanger: COSMIC ID:906800 1205Lu cell LCL-1236 disease: primary superficial spreading melanoma in vertical growth phase; from lung metastases in mice 1205Lu ATCC: CRL-2812 1321N1 cell HyperCLDB: cl5 disease: astrocytoma LCL-1393 1321N1 ECACC: 86030402 143B cell ATCC: CRL-8303 143B LCL-1417 CHEMBL: CHEMBL3307382 CVCL: CVCL_2270 143B PML BK TK cell ATCC: CRL-8304 LCL-1418 143B PML BK TK ZN 184A1 cell LCL-2080 184A1 ATCC: CRL-8798 CRL-8798 184B5 cell CRL-8799 LCL-2081 184B5 ATCC: CRL-8799 disease: chemically transformed 1A6 cell disease: carcinoma; produces p-CSF LCL-1703 ATCC: CRL-2742 1A6 22RV1 cell 22RV1 ATCC: CRL-2505 disease: prostate carcinoma HyperCLDB: cl7072 LCL-1145 23132/87 cell 23132/87 DSMZ: ACC 201 HyperCLDB: cl38 LCL-1532 2B8 cell disease: Burkitts lymphoma ATCC: CRL-12569 LCL-2015 2B8 42-MG-BA cell disease: glioblastoma,malignant glioma DSMZ: ACC 431 HyperCLDB: cl5011 LCL-1347 42-MG-BA 5637 cell 5637 EFO: EFO_0002096 CVCL: CVCL_0126 LCL-1702 ATCC: HTB-9 CHEMBL: CHEMBL3308352 639-V cell CVCL: CVCL_1048 DSMZ: ACC 413 LCL-1943 HyperCLDB: cl5012 639-V disease: carcinoma, transitional cell EFO: EFO_0002097 CHEMBL: CHEMBL3308703 647-V cell LCL-1708 647-V EFO: EFO_0002098 DSMZ: ACC 414 HyperCLDB: cl5254 CVCL: CVCL_1049 CHEMBL: CHEMBL3308704 769-P cell CHEMBL: CHEMBL3308705 LCL-1772 CVCL: CVCL_1050 769-P EFO: EFO_0002099 ATCC: CRL-1933 786-O cell LCL-1773 786-O ATCC: CRL-1932 disease: renal cell adenocarcinoma 8305C cell CHEMBL: CHEMBL3308706 8305C DSMZ: ACC 133 HyperCLDB: cl132 disease: carcinoma, undifferentiated CVCL: CVCL_1053 LCL-1685 8505C cell DSMZ: ACC 219 CHEMBL: CHEMBL3308353 8505C LCL-1686 disease: carcinoma, undifferentiated HyperCLDB: cl135 CVCL: CVCL_1054 8-MG-BA cell Sanger: COSMIC ID:687562 8-MG-BA CHEMBL: CHEMBL3308251 HyperCLDB: cl5013 LCL-1365 CVCL: CVCL_1052 A101D cell CHEMBL: CHEMBL3308182 A101D ATCC: CRL-7898 LCL-1267 ATCC: CRL-7898,COSMIC ID:910921; ATCC CRL-7898 CVCL: CVCL_1057 EFO: EFO_0002100 A172 cell ZN ATCC: CRL-1620 LCL-1348 A172 A-204 cell LCL-1409 ATCC: HTB-82 CHEMBL: CHEMBL3308354 ZN CVCL: CVCL_1058 EFO: EFO_0002102 A-204 A2058 cell CHEMBL: CHEMBL3308030 disease: malignant melanoma (skin primary) A2058 ATCC: CRL-11147 CVCL: CVCL_1059 LCL-1237 A253 cell A253 Sanger: COSMIC ID:906794 ATCC: CRL-7902 LCL-2034 A2780 cell HyperCLDB: cl193 CVCL: CVCL_0134 A2780 ECACC: 93112519 LCL-1518 CHEMBL: CHEMBL3308421 A2780ADR cell HyperCLDB: cl5047 A2780ADR LCL-1694 ECACC: 93112520 A2780cis cell ZN ECACC: 93112517 A2780cis LCL-1696 HyperCLDB: cl195 A3 cell ATCC: CRL-2570 LCL-1026 A3 disease: acute T cell leukemia A-375 cell EFO: EFO_0002103 LCL-1235 CVCL: CVCL_0132 CHEMBL: CHEMBL3308077 disease: malignant melanoma A-375 ATCC: CRL-1619 A375.S2 cell WEB: http://www.atcc.org/products/all/CRL-1872 disease: malignant melanoma A375.S2 JX, YH LCL-1231 ATCC: CRL-1872 A388 cell CVCL: CVCL_1063 LCL-1342 ATCC: CRL-7905 disease: carcinoma ATCC: COSMIC ID:910697; ATCC CRL-7905,CRL-7905 A388 CHEMBL: CHEMBL3308159 A-427 cell CVCL: CVCL_1055 A-427 CHEMBL: CHEMBL3307775 EFO: EFO_0002104 ATCC: HTB-53 LCL-1600 A431 cell ECACC: 85090402 HyperCLDB: cl160 ZN A431 LCL-1404 A549 cell LCL-1601 CHEMBL: CHEMBL3307651 CVCL: CVCL_0023 ATCC: CCL-185 EFO: EFO_0001086 HyperCLDB: cl207 A549 A673 cell HyperCLDB: cl166 disease: rhabdomyosarcoma LCL-1410 ECACC: 85111504 A673 A704 cell A704 Sanger: COSMIC ID:910920 LCL-1762 ATCC: CRL-7911 ABC-1 cell CVCL: CVCL_1066 EFO: EFO_0002813 CHEMBL: CHEMBL3308707 ABC-1 HyperCLDB: cl230 LCL-1634 ZN JHSF: JCRB0815 ACHN cell LCL-1756 EFO: EFO_0002108 ACHN ATCC: CRL-1611 CHEMBL: CHEMBL3307633 CVCL: CVCL_1067 ACN cell HyperCLDB: cl239 LCL-1982 ACN Sanger: COSMIC ID:906803 CHEMBL: CHEMBL3308148 CVCL: CVCL_1068 AGS cell CHEMBL: CHEMBL3308078 disease: gastric adenocarcinoma CVCL: CVCL_0139 EFO: EFO_0002109 AGS LCL-1893 ATCC: CRL-1739 ALL-PO cell ALL-PO HyperCLDB: cl5399 Sanger: COSMIC ID:910944 CVCL: CVCL_1069 LCL-1043 CHEMBL: CHEMBL3308227 ARH-77 cell LCL-2041 ARH-77 ATCC: CRL-1621 AsPC-1 cell CVCL: CVCL_0152 ATCC: CRL-1682 CHEMBL: CHEMBL3307994 AsPC-1 LCL-1730 disease: adenocarcinoma (pancreas primary) EFO: EFO_0002112 AU565 cell ZN LCL-1462 disease: adenocarcinoma (mammary gland primary) ATCC: CRL-2351 AU565 EFO: EFO_0001087 CHEMBL: CHEMBL3308095 CVCL: CVCL_1074 BC-1 cell LCL-1956 BC-1 ATCC: CRL-2230 disease: lymphoma; EBV and KSHV positive BC-2 cell ATCC: CRL-2231 BC-2 LCL-1957 disease: lymphoma; EBV and KSHV positive BC-3 cell BC-3 ATCC: CRL-2277 CHEMBL: CHEMBL3308890 CVCL: CVCL_1080 LCL-1948 disease: lymphoma; KSHV positive EFO: EFO_0002046 B-CPAP cell CVCL: CVCL_0153 HyperCLDB: cl5021 LCL-1687 DSMZ: ACC 273 B-CPAP CHEMBL: CHEMBL3308356 ZN BDCM cell ATCC: CRL-2740 BDCM LCL-1049 BE(2)-C cell ATCC: CRL-2268 LCL-1963 BE(2)-C BE(2)-M17 cell ATCC: CRL-2267 disease: neuroblastoma (brain primary) LCL-1972 BE(2)-M17 BE-13 cell BE-13 LCL-1044 Sanger: COSMIC ID:906763 CHEMBL: CHEMBL3308184 CVCL: CVCL_1081 HyperCLDB: cl5030 BEN cell DSMZ: ACC 254 ZN HyperCLDB: cl414 CVCL: CVCL_1082 BEN LCL-1602 CHEMBL: CHEMBL3308709 BeWo cell BeWo EFO: EFO_0002050 LCL-1293 CVCL: CVCL_0044 disease: choriocarcinoma ATCC: CCL-98 CHEMBL: CHEMBL3308359 BFTC-905 cell DSMZ: ACC 361 LCL-1710 BFTC-905 EFO: EFO_0002115 CHEMBL: CHEMBL3308470 ZN HyperCLDB: cl5031 CVCL: CVCL_1083 BFTC-909 cell BFTC-909 HyperCLDB: cl5032 CHEMBL: CHEMBL3308710 LCL-1921 disease: carcinoma, transitional cell CVCL: CVCL_1084 DSMZ: ACC 367 BHT-101 cell BHT-101 EFO: EFO_0002116 CHEMBL: CHEMBL3308096 LCL-1688 CVCL: CVCL_1085 HyperCLDB: cl5033 DSMZ: ACC 279 BHY cell DSMZ: ACC 404 CVCL: CVCL_1086 LCL-1208 BHY CHEMBL: CHEMBL3308711 HyperCLDB: cl5034 disease: oral cavity cancer,squamous cell carcinoma BL-41 cell CVCL: CVCL_1087 BL-41 CHEMBL: CHEMBL3308526 LCL-2028 HyperCLDB: cl459 DSMZ: ACC 160 BL-70 cell BL-70 DSMZ: ACC 233 CHEMBL: CHEMBL3308185 LCL-2016 CVCL: CVCL_1088 HyperCLDB: cl460 BPH-1 cell LCL-2095 WEB: http://capcelllines.ca/details.asp?id=132 BPH-1 HyperCLDB: cl5259 Web: http://www.ncbi.nlm.nih.gov/pubmed/7535634 disease: hyperplasia,benign BT-20 cell BT-20 LCL-1476 ZN CVCL: CVCL_0178 ATCC: HTB-19 EFO: EFO_0001092 CHEMBL: CHEMBL3307766 BT-474 cell CVCL: CVCL_0179 ATCC: HTB-20 EFO: EFO_0001093 BT-474 disease: ductal carcinoma CHEMBL: CHEMBL3307636 LCL-1308 BT-483 cell disease: invasive ductal carcinoma ATCC: HTB-121 LCL-1309 BT-483 BT-549 cell CVCL: CVCL_1092 EFO: EFO_0001096 BT-549 LCL-1310 CHEMBL: CHEMBL3308490 ATCC: HTB-122 disease: ductal carcinoma BV-173 cell HyperCLDB: cl510 CHEMBL: CHEMBL3308228 LCL-1111 disease: leukemia, pre-B cell BV-173 Sanger: COSMIC ID:910710 CVCL: CVCL_0181 BxPC-3 cell EFO: EFO_0002709 CVCL: CVCL_0186 ATCC: CRL-1687 LCL-1731 CHEMBL: CHEMBL3307637 HyperCLDB: cl516 BxPC-3 HyperCLDB: cl518 C2BBe1 cell C2BBe1 ATCC: CRL-2102 disease: colon adenocarcinoma CHEMBL: CHEMBL3308231 CVCL: CVCL_1096 LCL-1296 C32 cell CHEMBL: CHEMBL3308713 C32 LCL-1238 CVCL: CVCL_1097 ATCC: CRL-1585 disease: melanoma C-33 A cell ATCC: HTB-31 disease: cervix carcinoma C-33 A LCL-1300 C3A cell EFO: EFO_0002121 disease: hepatocellular carcinoma LCL-1927 C3A ATCC: CRL-10741 CVCL: CVCL_1098 CHEMBL: CHEMBL3308377 C-4 I cell C-4 I ATCC: CRL-1594 LCL-1301 C-4 II cell disease: cervix carcinoma LCL-1302 C-4 II ATCC: CRL-1595 C8166 cell HyperCLDB: cl589 CHEMBL: CHEMBL3307638 ECACC: 88051601 CVCL: CVCL_1099 C8166 LCL-1011 disease: acute T cell leukemia Ca Ski cell Ca Ski ATCC: CRL-1550 ECACC: 87020501 ZN LCL-1541 CA46 cell CA46 disease: Burkitts lymphoma CHEMBL: CHEMBL3308488 LCL-2017 CVCL: CVCL_1101 HyperCLDB: cl609 EFO: EFO_0002124 ATCC: CRL-1648 Caco-2 cell CVCL: CVCL_0025 LCL-1170 CHEMBL: CHEMBL3307519 Caco-2 ATCC: HTB-37 disease: colorectal adenocarcinoma MeSH: D018938 EFO: EFO_0001099 HyperCLDB: cl618 Caki-1 cell disease: clear cell carcinoma (kidney primary) ATCC: HTB-46 CHEMBL: CHEMBL3307522 CVCL: CVCL_0234 Caki-1 LCL-1774 EFO: EFO_0002149 CAL 27 cell disease: tongue cancer,squamous cell carcinoma ATCC: CRL-2095 LCL-1215 CAL 27 CAL-120 cell CHEMBL: CHEMBL3308577 HyperCLDB: cl7083 disease: adenocarcinoma, breast DSMZ: ACC 459 LCL-1463 CVCL: CVCL_1104 CAL-120 EFO: EFO_0005356 CAL-12T cell CAL-12T CHEMBL: CHEMBL3308132 LCL-1603 DSMZ: ACC 443 HyperCLDB: cl7084 ZN CVCL: CVCL_1105 CAL-148 cell HyperCLDB: cl7085 ZN CVCL: CVCL_1106 CHEMBL: CHEMBL3308794 CAL-148 LCL-1464 EFO: EFO_0005357 DSMZ: ACC 460 disease: adenocarcinoma, breast CAL-33 cell CHEMBL: CHEMBL3308715 HyperCLDB: cl7087 LCL-1216 CAL-33 CVCL: CVCL_1108 DSMZ: ACC 447 disease: tongue cancer,squamous cell carcinoma CAL-39 cell HyperCLDB: cl630 DSMZ: ACC 187 disease: carcinoma, squamous cell CAL-39 LCL-1294 CHEMBL: CHEMBL3308716 CVCL: CVCL_1109 CAL-51 cell HyperCLDB: cl5037 CHEMBL: CHEMBL3308717 LCL-1472 DSMZ: ACC 302 CAL-51 CVCL: CVCL_1110 EFO: EFO_0005358 CAL-54 cell HyperCLDB: cl5038 CAL-54 CHEMBL: CHEMBL3308346 LCL-1757 CVCL: CVCL_1111 EFO: EFO_0002125 DSMZ: ACC 365 CAL-62 cell HyperCLDB: cl7088 disease: carcinoma, anaplastic EFO: EFO_0002126 CAL-62 LCL-1683 DSMZ: ACC 448 CHEMBL: CHEMBL3308099 CVCL: CVCL_1112 CAL-72 cell ZN CHEMBL: CHEMBL3308718 LCL-1419 CAL-72 CVCL: CVCL_1113 HyperCLDB: cl7089 DSMZ: ACC 439 CAL-78 cell CAL-78 ZN HyperCLDB: cl7090 DSMZ: ACC 449 LCL-1457 CAL-85-1 cell CHEMBL: CHEMBL3308700 CVCL: CVCL_1114 LCL-1465 HyperCLDB: cl7091 CAL-85-1 EFO: EFO_0005359 disease: adenocarcinoma, breast DSMZ: ACC 440 Calu-1 cell ATCC: HTB-54 EFO: EFO_0002151 disease: epidermoid carcinoma (lung primary) ZN CHEMBL: CHEMBL3308031 LCL-1580 CVCL: CVCL_0608 Calu-1 HyperCLDB: cl632 HyperCLDB: cl631 Calu-3 cell LCL-1631 Calu-3 CVCL: CVCL_0609 EFO: EFO_0002819 ATCC: HTB-55 CHEMBL: CHEMBL3307390 disease: adenocarcinoma (lung primary) ZN Calu-6 cell ZN CHEMBL: CHEMBL3307639 Sanger: COSMIC ID:724859 ATCC: HTB-56 EFO: EFO_0002152 LCL-1626 CVCL: CVCL_0236 Calu-6 disease: unknown, probably lung anaplastic carcinoma CAMA-1 cell ZN ATCC: HTB-21 CHEMBL: CHEMBL3308719 CAMA-1 LCL-1466 EFO: EFO_0001100 CVCL: CVCL_1115 Caov-3 cell ZN ATCC: HTB-75 Caov-3 LCL-1519 Caov-4 cell LCL-1520 ATCC: HTB-76 CVCL: CVCL_0202 disease: adenocarcinoma (ovary primary) CHEMBL: CHEMBL3308232 ZN Caov-4 Capan-1 cell disease: adenocarcinoma (pancreas primary) EFO: EFO_0002153 HyperCLDB: cl639 CHEMBL: CHEMBL3307640 ATCC: HTB-79 CVCL: CVCL_0237 HyperCLDB: cl640 Capan-1 LCL-1732 Capan-2 cell LCL-1733 CVCL: CVCL_0026 CHEMBL: CHEMBL3308720 EFO: EFO_0002154 HyperCLDB: cl644 Capan-2 ATCC: HTB-80 HyperCLDB: cl642 CAS-1 cell HyperCLDB: cl4963 Sanger: COSMIC ID:910943 ZN CVCL: CVCL_1117 CHEMBL: CHEMBL3308187 LCL-1369 CAS-1 CCF-STTG1 cell CCF-STTG1 disease: astrocytoma CVCL: CVCL_1118 CHEMBL: CHEMBL3308795 EFO: EFO_0002127 LCL-1394 ATCC: CRL-1718 CCRF-CEM cell disease: acute lymphoblastic leukemia CCRF-CEM EFO: EFO_0002128 CVCL: CVCL_0207 ATCC: CCL-119 LCL-1012 CHEMBL: CHEMBL3307641 CCRF-HSB-2 cell ATCC: CCL-120.1 LCL-1914 CCRF-HSB-2 disease: acute lymphoblastic leukemia CCRF-SB cell JX, YH CHEMBL: CHEMBL3307643 LCL-1006 ATCC: CCL-120 CVCL: CVCL_1860 CCRF-SB CCL-120 CEM/C1 cell LCL-1034 disease: acute lymphoblastic leukemia CEM/C1 ATCC: CRL-2265 CEM/C2 cell CHEMBL: CHEMBL3307952 CVCL: CVCL_3497 LCL-1035 ATCC: CRL-2264 CEM/C2 disease: acute lymphoblastic leukemia CESS cell CHEMBL: CHEMBL3308863 EFO: EFO_0002130 LCL-1050 ATCC: TIB-190 CESS disease: myelomonocytic leukemia CVCL: CVCL_0209 CFPAC-1 cell CVCL: CVCL_1119 disease: ductal adenocarcinoma; cystic fibrosis CHEMBL: CHEMBL3308032 CFPAC-1 ATCC: CRL-1918 LCL-1748 CGTH-W-1 cell CGTH-W-1 CVCL: CVCL_1120 DSMZ: ACC 360,COSMIC ID:910568; DSMZ ACC 360 HyperCLDB: cl5040 LCL-1691 CHEMBL: CHEMBL3308849 ChaGo-K-1 cell ZN ATCC: HTB-168 LCL-1579 ChaGo-K-1 CVCL: CVCL_1121 EFO: EFO_0002155 disease: bronchogenic carcinoma (bronchus primary) CHEMBL: CHEMBL3308489 CHP-126 cell DSMZ: ACC 304 LCL-1973 HyperCLDB: cl776 CVCL: CVCL_1123 CHEMBL: CHEMBL3308252 CHP-126 CHP-212 cell ATCC: CRL-2273 CHP-212 disease: brain, neuroblastoma LCL-1964 Clone 15 HL-60 cell CRL-1964 LCL-1081 ATCC: CRL-1964 Clone 15 HL-60 disease: promyeloblast; acute promyelocytic leukemia CMK cell DSMZ: ACC 392 LCL-1051 CMK disease: leukemia, acute megacaryocytic CHEMBL: CHEMBL3308149 EFO: EFO_0003037 CVCL: CVCL_0216 HyperCLDB: cl5042 COLO 201 cell COLO 201 ATCC: CCL-224 LCL-1172 disease: colorectal adenocarcinoma (colon primary) ECACC: 87091201 COLO 205 cell CHEMBL: CHEMBL3308348 LCL-1173 COLO 205 disease: colorectal adenocarcinoma (colon primary) CVCL: CVCL_0218 EFO: EFO_0003082 ATCC: CCL-222 ECACC: 87061208 COLO 320DM cell COLO 320DM CHEMBL: CHEMBL3307647 ATCC: CCL-220 EFO: EFO_0002136 LCL-1197 CVCL: CVCL_0219 disease: colorectal adenocarcinoma COLO 684 cell ECACC: 87061203 HyperCLDB: cl841 COLO 684 LCL-1504 COLO 741 cell disease: carcinoma, colon LCL-1158 HyperCLDB: cl848 COLO 741 ECACC: 93052621 COLO 792 cell LCL-1239 ECACC: 93052616 COLO 792 HyperCLDB: cl851 disease: malignant melanoma COLO 853 cell COLO 853 LCL-1240 disease: melanoma HyperCLDB: cl859 ECACC: 93052606 COLO 857 cell COLO 857 ECACC: 93051120 HyperCLDB: cl861 LCL-1241 COLO 858 cell ECACC: 93052613 HyperCLDB: cl862 COLO 858 LCL-1242 COLO-206F cell COLO-206F disease: colon carcinoma HyperCLDB: cl864 DSMZ: ACC 21 LCL-1159 COLO-320 cell HyperCLDB: cl828 COLO-320 DSMZ: ACC 144 LCL-1174 COLO-678 cell DSMZ: ACC 194 HyperCLDB: cl865 COLO-678 LCL-1160 CHEMBL: CHEMBL3308349 disease: colon carcinoma CVCL: CVCL_1129 COLO-680N cell DSMZ: ACC 182 CHEMBL: CHEMBL3308724 CVCL: CVCL_1131 LCL-1551 disease: carcinoma, squamous cell COLO-680N HyperCLDB: cl866 COLO-704 cell DSMZ: ACC 198 COLO-704 LCL-1531 HyperCLDB: cl869 COLO-783 cell COLO-783 LCL-1243 disease: melanoma DSMZ: ACC 257 HyperCLDB: cl5043 COLO-824 cell HyperCLDB: cl870 LCL-1477 CVCL: CVCL_1136 CHEMBL: CHEMBL3308725 DSMZ: ACC 200 COLO-824 COLO-849 cell DSMZ: ACC 216 HyperCLDB: cl872 LCL-1245 COLO-849 disease: melanoma COR-L 23/CPR cell ECACC: 96042336 COR-L 23/CPR disease: carcinoma, large cell HyperCLDB: cl5053 LCL-1779 COR-L23 cell CVCL: CVCL_1139 LCL-1780 disease: carcinoma, large cell CHEMBL: CHEMBL3308073 HyperCLDB: cl877 EFO: EFO_0002142 ECACC: 92031919 COR-L23 COR-L279 cell CHEMBL: CHEMBL3308549 disease: carcinoma, small cell COR-L279 ECACC: 96020724 HyperCLDB: cl880 CVCL: CVCL_1140 LCL-1825 COR-L51 cell HyperCLDB: cl883 disease: carcinoma, lung small cell COR-L51 ECACC: 92031916,92031916; COSMIC ID:910555 LCL-1826 COR-L88 cell HyperCLDB: cl884 disease: carcinoma, lung small cell LCL-1827 COR-L88 CVCL: CVCL_1141 CHEMBL: CHEMBL3308865 ECACC: 92031917 COR-L95 cell LCL-1828 COR-L95 HyperCLDB: cl5057 disease: carcinoma, small cell ECACC: 96020733 CPC-N cell disease: carcinoma, small cell CPC-N HyperCLDB: cl5044 CHEMBL: CHEMBL3308830 LCL-1829 DSMZ: ACC 306 CVCL: CVCL_1146 CTV-1 cell CTV-1 CVCL: CVCL_1150 CHEMBL: CHEMBL3308189 HyperCLDB: cl927 disease: leukemia, acute myeloid LCL-1013 DSMZ: ACC 40 D283 Med cell D283 Med ZN disease: medulloblastoma (cerebellum primary) LCL-1577 ATCC: HTB-185 DAN-G cell CVCL: CVCL_0243 HyperCLDB: cl982 DSMZ: ACC 249 CHEMBL: CHEMBL3307281 DAN-G LCL-1734 Daoy cell LCL-1576 disease: desmoplastic cerebellar medulloblastoma CHEMBL: CHEMBL3308510 ZN ATCC: HTB-186 Daoy CVCL: CVCL_1167 Daudi cell LCL-2018 HyperCLDB: cl995 CHEMBL: CHEMBL3307579 EFO: EFO_0002169 ATCC: CCL-213 Daudi CVCL: CVCL_0008 DB cell disease: large cell lymphoma EFO: EFO_0002158 ATCC: CRL-2289 CHEMBL: CHEMBL3308866 LCL-1119 DB CVCL: CVCL_1168 DBTRG-05MG cell EFO: EFO_0002159 DBTRG-05MG disease: glioblastoma LCL-1349 ATCC: CRL-2020 CVCL: CVCL_1169 CHEMBL: CHEMBL3308485 Detroit 562 cell ECACC: 87042205 CHEMBL: CHEMBL3308486 disease: carcinoma (pharynx primary) CVCL: CVCL_1171 Detroit 562 LCL-1226 EFO: EFO_0002170 ATCC: CCL-138 DG-75 cell CVCL: CVCL_0244 CHEMBL: CHEMBL3308527 HyperCLDB: cl1051 ATCC: CRL-2625 DG-75 LCL-2019 DK-MG cell HyperCLDB: cl5262 ZN EFO: EFO_0002161 LCL-1350 CVCL: CVCL_1173 DK-MG CHEMBL: CHEMBL3308814 DSMZ: ACC 277 DLD-1 cell ATCC: CCL-221 CVCL: CVCL_0248 CHEMBL: CHEMBL3307580 disease: colorectal adenocarcinoma DLD-1 LCL-1175 DMS 114 cell disease: carcinoma; small cell lung cancer ATCC: CRL-2066 LCL-1830 DMS 114 DMS 153 cell DMS 153 ATCC: CRL-2064 LCL-1831 disease: carcinoma; small cell lung cancer (lung primary) DMS 273 cell DMS 273 HyperCLDB: cl1079 LCL-1807 ECACC: 95062830 disease: carcinoma, small cell DMS 53 cell DMS 53 LCL-1808 ATCC: CRL-2062 disease: carcinoma; small cell lung cancer DMS 79 cell DMS 79 ATCC: CRL-2049 disease: carcinoma; small cell lung cancer LCL-1832 DoTc2 4510 cell DoTc2 4510 ATCC: CRL-7920 LCL-1303 DU 145 cell disease: carcinoma (prostate primary) ATCC: HTB-81 DU 145 LCL-1146 DU4475 cell DU4475 ATCC: HTB-123 HyperCLDB: cl5264 disease: ductal carcinoma LCL-1323 DV-90 cell LCL-1636 DSMZ: ACC 307 CHEMBL: CHEMBL3308729 HyperCLDB: cl5265 DV-90 CVCL: CVCL_1184 EB1 cell LCL-2030 EB1 disease: Burkitts lymphoma ATCC: HTB-60 EB2 cell CVCL: CVCL_1186 EFO: EFO_0002173 disease: Burkitts lymphoma (B lymphocyte primary) ATCC: HTB-61 EB2 LCL-2031 CHEMBL: CHEMBL3308867 EB-3 cell CVCL: CVCL_1185 LCL-2032 disease: Burkitts lymphoma EB-3 ATCC: CCL-85 CHEMBL: CHEMBL3308824 EFE-184 cell HyperCLDB: cl1140 DSMZ: ACC 230 CHEMBL: CHEMBL3308103 EFE-184 LCL-1494 CVCL: CVCL_1191 EFM-19 cell DSMZ: ACC 231 HyperCLDB: cl1141 CVCL: CVCL_0253 CHEMBL: CHEMBL3308502 LCL-1311 EFO: EFO_0002175 EFM-19 EFM-192A cell EFM-192A LCL-1478 DSMZ: ACC 258 HyperCLDB: cl5267 ZN EFM-192B cell LCL-1312 DSMZ: ACC 308 HyperCLDB: cl5268 EFM-192B EFM-192C cell LCL-1479 HyperCLDB: cl5269 ZN DSMZ: ACC 311 EFM-192C EFO-21 cell EFO-21 disease: cystoadenocarcinoma CHEMBL: CHEMBL3308730 LCL-1515 DSMZ: ACC 235 HyperCLDB: cl1142 CVCL: CVCL_0029 EFO-27 cell HyperCLDB: cl1143 CVCL: CVCL_1192 CHEMBL: CHEMBL3308134 EFO-27 LCL-1521 DSMZ: ACC 191 EGI-1 cell EGI-1 HyperCLDB: cl5270 DSMZ: ACC 385 CVCL: CVCL_1193 CHEMBL: CHEMBL3308731 LCL-1787 EHEB cell LCL-1085 CVCL: CVCL_1194 disease: leukemia, chronic, B cell CHEMBL: CHEMBL3308163 ACC 67 EHEB HyperCLDB: cl1146 EJ138 cell LCL-1704 ECACC: 85061108 HyperCLDB: cl1154 EJ138 EM-2 cell Sanger: COSMIC ID:906855 EM-2 CHEMBL: CHEMBL3308889 LCL-1112 disease: leukemia, chronic myeloid CVCL: CVCL_1196 EFO: EFO_0002176 HyperCLDB: cl1164 Eos-HL-60 cell Eos-HL-60 LCL-2055 96100920 HyperCLDB: cl5062 EPLC-272H cell HyperCLDB: cl5272 EPLC-272H disease: carcinoma, epidermoid DSMZ: ACC 383 CVCL: CVCL_1197 LCL-1581 CHEMBL: CHEMBL3308104 ES-2 cell ES-2 disease: clear cell carcinoma ATCC: CRL-1978 LCL-1806 ESS-1 cell ESS-1 disease: sarcoma-stromal DSMZ: ACC 461 CVCL: CVCL_1205 LCL-1507 CHEMBL: CHEMBL3308384 HyperCLDB: cl7098 EVSA-T cell EVSA-T CHEMBL: CHEMBL3307361 HyperCLDB: cl5273 CVCL: CVCL_1207 LCL-1313 DSMZ: ACC 433 FaDu cell ATCC: HTB-43 CVCL: CVCL_1218 EFO: EFO_0002178 LCL-1201 disease: squamous cell carcinoma CHEMBL: CHEMBL3307943 FaDu Farage cell LCL-1131 disease: non-Hodgkins lymphoma ATCC: CRL-2630 Farage FLYA13 cell disease: fibrosarcoma LCL-1437 FLYA13 HyperCLDB: cl1376 ECACC: 95091901 FTC-133 cell CHEMBL: CHEMBL3308732 HyperCLDB: cl1398 LCL-1677 FTC-133 ECACC: 94060901 CVCL: CVCL_1219 FTC-238 cell HyperCLDB: cl1400 LCL-1678 FTC-238 ECACC: 94060902 FU-OV-1 cell DSMZ: ACC 444 HyperCLDB: cl7099 LCL-1695 FU-OV-1 G-361 cell ATCC: CRL-1424 LCL-1246 CVCL: CVCL_1220 disease: malignant melanoma G-361 CHEMBL: CHEMBL3307514 G-401 cell ATCC: CRL-1441 G-401 EFO: EFO_0002179 CVCL: CVCL_0270 CHEMBL: CHEMBL3308394 LCL-1511 disease: rhabdoid tumor G-402 cell disease: renal leiomyoblastoma LCL-1751 CHEMBL: CHEMBL3308733 G-402 EFO: EFO_0002180 CVCL: CVCL_1221 ATCC: CRL-1440 GA-10 cell disease: Burkitts lymphoma LCL-2020 GA-10 ATCC: CRL-2392 GA-10 (Clone 20) cell GA-10 (Clone 20) ATCC: CRL-2394 LCL-2035 GAMG cell GAMG LCL-1351 CHEMBL: CHEMBL3308734 HyperCLDB: cl1441 ZN CVCL: CVCL_1226 DSMZ: ACC 242 GCT cell ATCC: TIB-223 EFO: EFO_0002182 LCL-1752 GCT CHEMBL: CHEMBL3308471 CVCL: CVCL_1229 disease: fibrous histiocytoma (primary unknown) GDM-1 cell CHEMBL: CHEMBL3308198 LCL-1052 disease: monoblast; myelomonoblastic leukemia EFO: EFO_0002183 GDM-1 ATCC: CRL-2627 CVCL: CVCL_1230 GI-ME-N cell Sanger: COSMIC ID:906872 GI-ME-N HyperCLDB: cl1464 LCL-1983 CVCL: CVCL_1232 CHEMBL: CHEMBL3308868 GMS-10 cell HyperCLDB: cl5277 CVCL: CVCL_1233 GMS-10 LCL-1352 disease: glioblastoma DSMZ: ACC 405 CHEMBL: CHEMBL3308105 GOS-3 cell disease: astrocytoma/oligodendroglioma GOS-3 LCL-1406 HyperCLDB: cl5278 DSMZ: ACC 408 GP5d cell CHEMBL: CHEMBL3308735 LCL-1176 CVCL: CVCL_1235 GP5d ECACC: 95090715 HyperCLDB: cl1512 GRANTA-519 cell LCL-1126 disease: lymphoma, B cell GRANTA-519 DSMZ: ACC 342 HyperCLDB: cl5279 H33HJ-JA1 cell LCL-2037 : 90112119 H33HJ-JA1 HyperCLDB: cl1542 H4 cell EFO: EFO_0002184 ATCC: HTB-148 CVCL: CVCL_1239 CHEMBL: CHEMBL3308507 LCL-1401 disease: neuroglioma H4 H69V cell H69V ECACC: 91091803 HyperCLDB: cl1554 LCL-1875 disease: carcinoma, small cell H9 cell disease: cutaneous T cell lymphoma ATCC: HTB-176 EFO: EFO_0003045 LCL-1144 Sanger: COSMIC ID:907043 H9 CHEMBL: CHEMBL3308402 CVCL: CVCL_1240 HC-1 cell HC-1 CHEMBL: CHEMBL3308522 HyperCLDB: cl5282 LCL-1086 CVCL: CVCL_1243 ACC 301 disease: leukemia, hairy cell HCC1143 cell CHEMBL: CHEMBL3308737 ATCC: CRL-2321 EFO: EFO_0001169 LCL-1329 disease: primary ductal carcinoma HCC1143 CVCL: CVCL_1245 HCC1187 cell EFO: EFO_0001170 ATCC: CRL-2322 disease: primary ductal carcinoma HCC1187 CVCL: CVCL_1247 LCL-1324 CHEMBL: CHEMBL3308845 HCC1395 cell LCL-1330 CVCL: CVCL_1249 CHEMBL: CHEMBL3308106 ATCC: CRL-2324 EFO: EFO_0002185 disease: primary ductal carcinoma HCC1395 HCC1419 cell ATCC: CRL-2326 EFO: EFO_0005372 CVCL: CVCL_1251 CHEMBL: CHEMBL3308738 LCL-1314 disease: primary ductal carcinoma HCC1419 HCC1428 cell disease: adenocarcinoma (mammary gland primary) ZN LCL-1467 ATCC: CRL-2327 HCC1428 HCC1500 cell disease: primary ductal carcinoma HCC1500 ATCC: CRL-2329 LCL-1325 HCC1569 cell LCL-1480 CVCL: CVCL_1255 EFO: EFO_0001173 ZN HCC1569 disease: primary metaplastic carcinoma CHEMBL: CHEMBL3308497 ATCC: CRL-2330 HCC1599 cell disease: primary ductal carcinoma CVCL: CVCL_1256 HCC1599 EFO: EFO_0002186 CHEMBL: CHEMBL3308262 LCL-1326 ATCC: CRL-2331 HCC1806 cell ATCC: CRL-2335 EFO: EFO_0005373 disease: primary acantholytic squamous cell carcinoma HCC1806 CVCL: CVCL_1258 CHEMBL: CHEMBL3308135 LCL-1960 HCC1937 cell disease: primary ductal carcinoma EFO: EFO_0001174 LCL-1331 CHEMBL: CHEMBL3308371 HCC1937 CVCL: CVCL_0290 ATCC: CRL-2336 HCC1954 cell HCC1954 disease: ductal carcinoma CVCL: CVCL_1259 CHEMBL: CHEMBL3308107 LCL-1332 ATCC: CRL-2338 EFO: EFO_0001175 HCC202 cell LCL-1333 HCC202 ATCC: CRL-2316 disease: primary ductal carcinoma HCC2157 cell ATCC: CRL-2340 EFO: EFO_0001177 LCL-1327 CVCL: CVCL_1261 HCC2157 disease: primary ductal carcinoma CHEMBL: CHEMBL3308891 HCC2218 cell disease: primary ductal carcinoma LCL-1328 CVCL: CVCL_1263 ATCC: CRL-2343 HCC2218 EFO: EFO_0002187 CHEMBL: CHEMBL3308869 HCC38 cell ATCC: CRL-2314 EFO: EFO_0001180 LCL-1334 CVCL: CVCL_1267 CHEMBL: CHEMBL3308578 HCC38 disease: primary ductal carcinoma HCC70 cell disease: primary ductal carcinoma EFO: EFO_0001181 CHEMBL: CHEMBL3308739 HCC70 ATCC: CRL-2315 LCL-1335 CVCL: CVCL_1270 HCT 116 cell HCT 116 ATCC: CCL-247 LCL-1161 MeSH: D045325 HyperCLDB: cl1575 disease: colorectal carcinoma ECACC: 91091005 HCT-15 cell CHEMBL: CHEMBL3307945 EFO: EFO_0002188 LCL-1178 HCT-15 disease: colorectal adenocarcinoma ATCC: CCL-225 CVCL: CVCL_0292 HCT-8 cell CVCL: CVCL_2478 LCL-1198 EFO: EFO_0002189 HyperCLDB: cl4949 ECACC: 90032006 CHEMBL: CHEMBL3308035 HCT-8 HDLM-2 cell HDLM-2 CHEMBL: CHEMBL3308234 ACC 17 CVCL: CVCL_0009 LCL-2007 HyperCLDB: cl1580 HD-MY-Z cell HyperCLDB: cl5284 CVCL: CVCL_1273 LCL-2008 ACC 346 CHEMBL: CHEMBL3308544 HD-MY-Z HEL cell HEL DSMZ: ACC 11 LCL-1053 CHEMBL: CHEMBL3308090 disease: erythroleukemia HyperCLDB: cl1585 CVCL: CVCL_0001 HEL 92.1.7 cell LCL-1076 disease: erythroleukemia HEL 92.1.7 ATCC: TIB-180 TIB-180 HeLa cell EFO: EFO_0001185 MeSH: D006367 ATCC: CCL-2 CHEMBL: CHEMBL3308376 HyperCLDB: cl1601 HeLa LCL-1512 CVCL: CVCL_0030 H-EMC-SS cell CHEMBL: CHEMBL3308736 disease: chondrosarcoma ZN ECACC: 94042258 HyperCLDB: cl1625 CVCL: CVCL_1238 H-EMC-SS LCL-1458 Hep 3B2.1-7 cell ATCC: HB-8064 Hep 3B2.1-7 LCL-1924 disease: hepatocellular carcinoma Hep G2 cell disease: hepatocellular carcinoma Hep G2 ATCC: HB-8065 LCL-1925 HGC-27 cell ECACC: 94042256 HyperCLDB: cl1673 CHEMBL: CHEMBL3308741 HGC-27 LCL-1882 CVCL: CVCL_1279 HH cell HH EFO: EFO_0002194 CHEMBL: CHEMBL3308142 disease: cutaneous T cell lymphoma,non-Hodgkin lymphoma LCL-1141 ATCC: CRL-2105 CVCL: CVCL_1280 HL-60 cell HyperCLDB: cl1684 HyperCLDB: cl1689 EFO: EFO_0002793 disease: promyeloblast; acute promyelocytic leukemia CHEMBL: CHEMBL3307654 ATCC: CCL-240 CVCL: CVCL_0002 LCL-1054 MeSH: D018922 HL-60 HL-60/MX2 cell disease: promyeloblast; acute promyelocytic leukemia CRL-2257 ATCC: CRL-2257 LCL-1083 HL-60/MX2 HMVII cell LCL-1285 ECACC: 92042701 HyperCLDB: cl1700 HMVII HN cell DSMZ: ACC 417 CVCL: CVCL_1283 disease: hypernephroma LCL-1209 HyperCLDB: cl1701 disease: oral cavity cancer,squamous cell carcinoma CHEMBL: CHEMBL3308742 HN HOS cell HOS EFO: EFO_0002196 ZN LCL-1421 CHEMBL: CHEMBL3308811 ATCC: CRL-1543 CVCL: CVCL_0312 ECACC: 87070202 HPAC cell EFO: EFO_0002197 LCL-1735 ATCC: CRL-2119 CHEMBL: CHEMBL3308388 HPAC CVCL: CVCL_3517 HPAF-II cell CVCL: CVCL_0313 HPAF-II EFO: EFO_0002198 LCL-1736 ATCC: CRL-1997 CHEMBL: CHEMBL3308744 HRT-18 cell HyperCLDB: cl1711 HRT-18 HyperCLDB: cl710 LCL-1289 ECACC: 86040306 Hs 257.T cell LCL-1179 disease: colorectal adenocarcinoma ATCC: CRL-7214 Hs 257.T Hs 445 cell disease: lymphoma; Hodgkins disease Hs 445 LCL-2006 ATCC: HTB-146 Hs 578T cell Hs 578T LCL-1315 ATCC: HTB-126 disease: ductal carcinoma Hs 588.T cell Hs 588.T ATCC: CRL-7850 LCL-1513 Hs 633T cell HyperCLDB: cl1718 ECACC: 89050201 Hs 633T LCL-1436 Hs 683 cell LCL-1402 CVCL: CVCL_0844 CHEMBL: CHEMBL3308452 Hs 683 ATCC: HTB-138 Hs 746T cell ATCC: HTB-135 CVCL: CVCL_0333 LCL-1883 disease: gastric carcinoma (stomach primary CHEMBL: CHEMBL3307498 Hs 746T Hs 766T cell disease: carcinoma (pancreas primary) Hs 766T ATCC: HTB-134 LCL-1737 HS-Sultan cell disease: Burkitts lymphoma ATCC: CRL-1484 LCL-2036 HS-Sultan HT cell LCL-1949 ATCC: CRL-2260 HT EFO: EFO_0002200 CVCL: CVCL_1290 CHEMBL: CHEMBL3308143 disease: diffuse mixed lymphoma; B lymphoblast HT 1080 cell disease: fibrosarcoma HyperCLDB: cl1736 LCL-1435 ECACC: 85111505 HT 1080 HT 1376 cell HT 1376 ECACC: 87032402 LCL-1712 HyperCLDB: cl1743 HT115 cell HyperCLDB: cl1756 LCL-1162 ECACC: 85061104 HT115 HT-1197 cell LCL-1713 CHEMBL: CHEMBL3308506 HT-1197 ATCC: CRL-1473 EFO: EFO_0002202 ZN CVCL: CVCL_1291 HT-144 cell CHEMBL: CHEMBL3308870 CVCL: CVCL_0318 ATCC: HTB-63,COSMIC ID:907067; ATCC HTB-63 LCL-1273 ATCC: HTB-63 disease: malignant melanoma HT-144 HT-29 cell CHEMBL: CHEMBL3307768 ATCC: HTB-38 CVCL: CVCL_0320 EFO: EFO_0001193 disease: colorectal adenocarcinoma HT-29 LCL-1180 MeSH: D019073 HyperCLDB: cl1752 HT-3 cell CVCL: CVCL_1293 disease: carcinoma (cervix primary) HT-3 CHEMBL: CHEMBL3308745 LCL-1304 EFO: EFO_0002204 ATCC: HTB-32 HT55 cell LCL-1163 CHEMBL: CHEMBL3308746 ECACC: 85061105 HT55 CVCL: CVCL_1294 HyperCLDB: cl1759 HUP-T3 cell HyperCLDB: cl1770 CHEMBL: CHEMBL3308399 CVCL: CVCL_1299 HUP-T3 DSMZ: ACC 259 LCL-1790 HUP-T4 cell HyperCLDB: cl1773 CHEMBL: CHEMBL3308815 HUP-T4 CVCL: CVCL_1300 DSMZ: ACC 223 LCL-1791 EFO: EFO_0002208 HuT 78 cell CVCL: CVCL_0337 HuT 78 ATCC: TIB-161 EFO: EFO_0002209 HyperCLDB: cl1779 LCL-2005 CHEMBL: CHEMBL3307500 I 2.1 cell disease: acute T cell leukemia LCL-1027 ATCC: CRL-2572 I 2.1 I 9.2 cell I 9.2 LCL-1028 disease: acute T cell leukemia ATCC: CRL-2571 IGR-1 cell LCL-1247 DSMZ: ACC 236 CVCL: CVCL_1303 CHEMBL: CHEMBL3308749 HyperCLDB: cl2624 IGR-1 disease: melanoma IGR-37 cell DSMZ: ACC 237 disease: melanoma HyperCLDB: cl2625 IGR-37 LCL-1248 IGR-39 cell IGR-39 disease: melanoma LCL-1249 DSMZ: ACC 239 HyperCLDB: cl2626 IM-9 cell IM-9 ATCC: CCL-159 LCL-1958 IMR-32 cell CVCL: CVCL_0346 HyperCLDB: cl2880 EFO: EFO_0001195 ATCC: CCL-127 LCL-1965 CHEMBL: CHEMBL3307656 IMR-32 IMR-5 cell IMR-5 CHEMBL: CHEMBL3308201 CVCL: CVCL_1306 Sanger: COSMIC ID:907170 HyperCLDB: cl5097 LCL-1984 IPC-298 cell IPC-298 DSMZ: ACC 251 CVCL: CVCL_1307 LCL-1250 disease: melanoma HyperCLDB: cl2901 CHEMBL: CHEMBL3308797 Ishikawa (Heraklio) 02 ER- cell LCL-1498 ECACC: 98032302 Ishikawa (Heraklio) 02 ER- ZN HyperCLDB: cl5071 IST-MEL1 cell CHEMBL: CHEMBL3308290 IST-MEL1 CVCL: CVCL_1308 Sanger: COSMIC ID:907172 HyperCLDB: cl5539 LCL-1234 IST-MES1 cell LCL-1228 IST-MES1 Sanger: COSMIC ID:907173 disease: mesothelioma CVCL: CVCL_1311 CHEMBL: CHEMBL3308291 HyperCLDB: cl5540 IST-SL1 cell disease: carcinoma, small cell LCL-1868 HyperCLDB: cl2908 CHEMBL: CHEMBL3308263 IST-SL1 CVCL: CVCL_1313 Sanger: COSMIC ID:753564 IST-SL2 cell CHEMBL: CHEMBL3308871 IST-SL2 LCL-1869 disease: carcinoma, small cell HyperCLDB: cl2909 CVCL: CVCL_1314 Sanger: COSMIC ID:753565 J.RT3-T3.5 cell disease: acute T cell leukemia JX, QL, ZN J.RT3-T3.5 ATCC: TIB-153 LCL-1014 J45.01 cell disease: acute T cell leukemia; CD45 deficient LCL-1029 J45.01 ATCC: CRL-1990 J82 cell disease: transitional cell carcinoma EFO: EFO_0002210 CVCL: CVCL_0359 CHEMBL: CHEMBL3308508 ATCC: HTB-1 J82 LCL-1714 JAR cell disease: choriocarcinoma EFO: EFO_0002211 ATCC: HTB-144 LCL-1491 JAR CVCL: CVCL_0360 CHEMBL: CHEMBL3307657 JEG-3 cell JEG-3 LCL-1492 CVCL: CVCL_0363 ATCC: HTB-36 HyperCLDB: cl2936 disease: choriocarcinoma CHEMBL: CHEMBL3308202 Sanger: COSMIC ID:907176 Jiyoye cell LCL-2021 Jiyoye disease: Burkitts lymphoma HyperCLDB: cl2946 ATCC: CCL-87 JM1 cell CVCL: CVCL_3532 ATCC: CRL-10423 LCL-1947 JM1 disease: leukemia; lymphoma CHEMBL: CHEMBL3308496 EFO: EFO_0002212 JSC-1 cell LCL-1959 JSC-1 ATCC: CRL-2769 disease: B cell lymphoma (metastatic site: peritoneal cavity) Jurkat, Clone E6-1 cell LCL-1030 disease: acute T cell leukemia ATCC: TIB-152 HyperCLDB: cl2962 Jurkat, Clone E6-1 JX JVM-2 cell JVM-2 HyperCLDB: cl2965 CHEMBL: CHEMBL3308530 COSMIC ID:907269 CVCL: CVCL_1319 disease: leukemia, chronic, B cell LCL-1099 JVM-3 cell JVM-3 LCL-1100 CVCL: CVCL_1320 HyperCLDB: cl2966 COSMIC ID:907270 CHEMBL: CHEMBL3308203 disease: leukemia, chronic, B cell K-562 cell CHEMBL: CHEMBL3308378 HyperCLDB: cl2980 K-562 EFO: EFO_0002067 MeSH: D020014 disease: chronic myelo- genous leukemia (bone marrow primary) ATCC: CCL-243 CVCL: CVCL_0004 LCL-1103 KARPAS-299 cell HyperCLDB: cl2995 KARPAS-299 CVCL: CVCL_1324 CHEMBL: CHEMBL3308327 DSMZ: ACC 31 disease: lymphoma, T cell LCL-1117 EFO: EFO_0005390 KARPAS-422 cell KARPAS-422 CHEMBL: CHEMBL3308328 LCL-1120 CVCL: CVCL_1325 DSMZ: ACC 32 HyperCLDB: cl2996 KARPAS-45 cell KARPAS-45 DSMZ: ACC 105 LCL-1015 disease: leukemia, T cell CHEMBL: CHEMBL3308305 HyperCLDB: cl35 CVCL: CVCL_1326 Kasumi-1 cell ATCC: CRL-2724 disease: acute myeloblastic leukemia Kasumi-1 LCL-1055 KATO III cell HyperCLDB: cl5214 ATCC: HTB-103 LCL-2003 disease: gastric carcinoma (stomach primary) HyperCLDB: cl3000 KATO III KE-37 cell CVCL: CVCL_1327 KE-37 disease: acute T cell leukemia LCL-1016 CHEMBL: CHEMBL3308872 HyperCLDB: cl3018 DSMZ: ACC 46 KELLY cell HyperCLDB: cl3020 DSMZ: ACC 355 KELLY LCL-1966 KG-1 cell LCL-1056 disease: myeloblast; acute lymphoblastic leukemia ATCC: CCL-246 KG-1 KG-1 cell ATCC: CCL-246 ATCC: CRL-8031 LCL-1056 KG-1 KG-1a cell LCL-1057 HyperCLDB: cl3027 KG-1a ATCC: CCL-246.1 disease: promyeloblast; acute lympho- blastic leukemia KHOS/NP cell KHOS/NP ECACC: 84102903 LCL-1425 HyperCLDB: cl3030 KHOS-240S cell ECACC: 86112810 KHOS-240S ATCC: CRL-1545 LCL-1426 KHOS-312H cell ECACC: 86112811 HyperCLDB: cl3029 LCL-1427 KHOS-312H KLE cell Sanger: COSMIC ID:924187 CVCL: CVCL_1329 KLE ATCC: CRL-1622 ZN CHEMBL: CHEMBL3308518 LCL-1505 EFO: EFO_0002220 KM-H2 cell HyperCLDB: cl3033 LCL-2009 ACC 8 CHEMBL: CHEMBL3308204 CVCL: CVCL_1330 KM-H2 KMOE-2 cell CHEMBL: CHEMBL3308236 HyperCLDB: cl3034 disease: erythremia acute CVCL: CVCL_1332 KMOE-2 LCL-1058 DSMZ: ACC 37 KPL-1 cell LCL-1483 KPL-1 DSMZ: ACC 317 HyperCLDB: cl5299 ZN KU-19-19 cell HyperCLDB: cl5300 CHEMBL: CHEMBL3308111 CVCL: CVCL_1344 LCL-1715 KU-19-19 disease: carcinoma, transitional cell DSMZ: ACC 395 KU812 cell LCL-1106 ATCC: CRL-2099 KU812 disease: chronic myelogenous leukemia KU812E cell ATCC: CRL-2100 KU812E disease: chronic myelogenous leukemia HyperCLDB: cl3071 LCL-1107 KU812F cell LCL-1108 ATCC: CRL-2101 KU812F HyperCLDB: cl3072 disease: chronic myelogenous leukemia KYSE-140 cell disease: carcinoma, squamous cell DSMZ: ACC 348 CHEMBL: CHEMBL3308752 CVCL: CVCL_1347 LCL-1547 HyperCLDB: cl5302 KYSE-140 KYSE-150 cell DSMZ: ACC 375 HyperCLDB: cl5303 disease: carcinoma, squamous cell KYSE-150 LCL-1548 KYSE-180 cell DSMZ: ACC 379 LCL-1549 KYSE-180 HyperCLDB: cl5304 CVCL: CVCL_1349 disease: carcinoma, squamous cell CHEMBL: CHEMBL3308389 KYSE-270 cell HyperCLDB: cl5305 CVCL: CVCL_1350 LCL-1552 DSMZ: ACC 380 KYSE-270 CHEMBL: CHEMBL3308753 disease: carcinoma, squamous cell KYSE-30 cell DSMZ: ACC 351 LCL-1553 HyperCLDB: cl5306 disease: carcinoma, squamous cell KYSE-30 KYSE-410 cell LCL-1554 KYSE-410 HyperCLDB: cl5307 CVCL: CVCL_1352 DSMZ: ACC 381 CHEMBL: CHEMBL3308754 disease: carcinoma, squamous cell KYSE-450 cell KYSE-450 disease: carcinoma, squamous cell HyperCLDB: cl5308 CVCL: CVCL_1353 DSMZ: ACC 387 LCL-1550 CHEMBL: CHEMBL3308755 KYSE-510 cell CHEMBL: CHEMBL3308081 CVCL: CVCL_1354 disease: carcinoma, squamous cell HyperCLDB: cl5309 LCL-1555 DSMZ: ACC 374 KYSE-510 KYSE-520 cell DSMZ: ACC 371 disease: carcinoma, squamous cell HyperCLDB: cl5310 KYSE-520 LCL-1556 KYSE-70 cell LCL-1557 KYSE-70 DSMZ: ACC 363 HyperCLDB: cl5311 disease: carcinoma, squamous cell L-363 cell DSMZ: ACC 49 disease: leukemia, plasma cell LCL-2045 CVCL: CVCL_1357 L-363 CHEMBL: CHEMBL3308205 HyperCLDB: cl3080 L-428 cell CHEMBL: CHEMBL3308873 LCL-2011 CVCL: CVCL_1361 L-428 HyperCLDB: cl3081 ACC 197 L-540 cell LCL-2012 CHEMBL: CHEMBL3308531 CVCL: CVCL_1362 ACC 72 L-540 HyperCLDB: cl455 LAMA-84 cell HyperCLDB: cl3168 CVCL: CVCL_0388 DSMZ: ACC 168 CHEMBL: CHEMBL3308267 LCL-1109 disease: leukemia, chronic myeloid LAMA-84 LAN-5 cell LAN-5 LCL-1987 HyperCLDB: cl3170 DSMZ: COSMIC ID:1161992; DSMZ ACC 673,ACC 673 LCLC-103H cell disease: carcinoma, large cell DSMZ: ACC 384 LCL-1781 HyperCLDB: cl5314 LCLC-103H LCLC-97TM1 cell HyperCLDB: cl5315 LCL-1782 CHEMBL: CHEMBL3308112 CVCL: CVCL_1376 LCLC-97TM1 DSMZ: ACC 388 disease: carcinoma, large cell LN-18 cell LCL-1353 disease: glioblastoma; apoptosis studies; p53+, p16, p14ARF ATCC: CRL-2610 LN-18 LN-229 cell disease: glioblastoma; apoptosis studies; p53+, p16, p14ARF LN-229 LCL-1354 ATCC: CRL-2611 LN-405 cell CHEMBL: CHEMBL3308756 HyperCLDB: cl3242 LN-405 ZN LCL-1395 DSMZ: ACC 189 CVCL: CVCL_1378 LNZTA3WT11 cell LNZTA3WT11 ATCC: CRL-11544 LCL-1355 disease: glioblastoma; p53 expression under tetracycline-induced promoter LNZTA3WT4 cell ATCC: CRL-11543 LCL-1345 disease: glioblastoma; p53 expression under tetracycline-induced promoter LNZTA3WT4 Loucy cell Loucy CHEMBL: CHEMBL3308208 ATCC: CRL-2629 LCL-1017 CVCL: CVCL_1380 HyperCLDB: cl5317 disease: acute T cell leukemia LOU-NH91 cell DSMZ: ACC 393 LOU-NH91 disease: carcinoma, squamous cell LCL-1588 HyperCLDB: cl5316 LoVo cell CVCL: CVCL_0399 LoVo disease: colorectal adenocarcinoma (colon primary) ATCC: CCL-229 LCL-1181 CHEMBL: CHEMBL3307691 LP-1 cell EFO: EFO_0003055 LP-1 CVCL: CVCL_0012 HyperCLDB: cl3252 CHEMBL: CHEMBL3308171 DSMZ: ACC 41 LCL-2046 LS174T cell HyperCLDB: cl3261 EFO: EFO_0002227 CHEMBL: CHEMBL3307536 LS174T CVCL: CVCL_1384 ECACC: 87060401 LCL-1182 LS180 cell LS180 HyperCLDB: cl3263 HyperCLDB: cl7120 ECACC: 87021202 LCL-1183 LUDLU-1 cell LUDLU-1 ECACC: 92012463 disease: carcinoma, squamous cell HyperCLDB: cl3269 LCL-1589 LXF-289 cell Sanger: COSMIC ID:753592 LCL-1668 HyperCLDB: cl3278 LXF-289 M059J cell ATCC: CRL-2366 disease: malignant glioblastoma; glioma CHEMBL: CHEMBL3308113 CVCL: CVCL_0400 LCL-1356 M059J M059K cell ATCC: CRL-2365 LCL-1362 disease: malignant glioblastoma; glioma M059K MB 157 cell ZN ATCC: CRL-7721 disease: carcinoma (mammary gland primary) LCL-1484 MB 157 MC/CAR cell ZN LCL-1538 MC/CAR ATCC: CRL-8083 disease: hybridoma fusion partner MC116 cell ATCC: CRL-1649 CHEMBL: CHEMBL3308210 disease: undifferentiated lymphoma lymphoblast CVCL: CVCL_1399 EFO: EFO_0002228 MC116 LCL-1946 MCF 10A cell PubMed: https://www.ncbi.nlm.nih.gov/pubmed/1975513 MCF10a MCF10A MCF-10A ATCC: CRL-10317 MCF-10A is a spontaneously immortalized, but nontransformed human mammary epithelial cell line cell that was derived from the breast tissue of a 36-year-old patient with fibrocystic changes Michigan Cancer Foundation 10A PubMed: https://www.ncbi.nlm.nih.gov/pubmed/12798140 MCF.10A MCF 10A disease: fibrocystic disease; non-tumorigenic Amelogenin: X; CSF1PO: 10,12; D13S317: 8,9; D16S539: 11,12; D18S51: 18,19; D21S11: 28,30; D3S1358: 14,18; D5S818: 10,13; D7S820: 10,11; D8S1179: 14,16; FGA: 22,24; Penta D: 10,12; Penta E: 13,14; TH01: 8,9.3; TPOX: 9,11; vWA: 15,17 CVCL: CVCL_0598; EFO: EFO_0001200; ChEMBL: CHEMBL3307364; HMSL: HMSL50583 LCL-2085 MCF 10F cell CVCL: CVCL_3633 disease: fibrocystic disease LCL-2102 Cosmic; 1136377 ATCC: CRL-10318 Michigan Cancer Foundation 10F MCF 10F MCF7 cell CVCL: CVCL_0031 EFO: EFO_0002082 disease: adenocarcinoma (mammary gland primary) ZN CHEMBL: CHEMBL3308403 ATCC: HTB-22 LCL-1460 MCF7 MC-IXC cell EFO: EFO_0002230 MC-IXC CHEMBL: CHEMBL3308758 LCL-1967 ATCC: CRL-2270 disease: neuroepithelioma (brain primary) CVCL: CVCL_1398 MDA-MB-134-VI cell LCL-1316 disease: ductal carcinoma (mammary gland primary) CHEMBL: CHEMBL3308340 ATCC: HTB-23 MDA-MB-134-VI EFO: EFO_0001205 CVCL: CVCL_0617 MDA-MB-157 cell CHEMBL: CHEMBL3308759 CVCL: CVCL_0618 EFO: EFO_0001206 disease: carcinoma (mammary gland primary) LCL-1916 ATCC: HTB-24 MDA-MB-157 MDA-MB-175-VII cell CHEMBL: CHEMBL3308404 disease: ductal carcinoma (mammary gland primary) EFO: EFO_0001208 LCL-1317 MDA-MB-175-VII CVCL: CVCL_1400 ATCC: HTB-25 MDA-MB-231 cell ZN CVCL: CVCL_0062 EFO: EFO_0001209 MDA-MB-231 CHEMBL: CHEMBL3307960 disease: adenocarcinoma (mammary gland primary) ATCC: HTB-26 LCL-1461 MDA-MB-330 cell disease: carcinoma (mammary gland primary) LCL-1961 MDA-MB-330 ATCC: HTB-127 MDA-MB-361 cell ATCC: HTB-27 CVCL: CVCL_0620 disease: adenocarcinoma (mammary gland primary) MDA-MB-361 EFO: EFO_0001211 LCL-1468 CHEMBL: CHEMBL3308405 ZN MDA-MB-415 cell EFO: EFO_0001212 CHEMBL: CHEMBL3308760 CVCL: CVCL_0621 ATCC: HTB-128 MDA-MB-415 LCL-1469 disease: adenocarcinoma (mammary gland primary) MDA-MB-435S cell ATCC: HTB-129 LCL-1307 disease: ductal carcinoma (mammary gland primary) MDA-MB-435S MDA-MB-436 cell ATCC: HTB-130 MDA-MB-436 LCL-1470 ZN MDA-MB-453 cell CHEMBL: CHEMBL3307596 ATCC: HTB-131 disease: carcinoma (mammary gland primary) LCL-1485 MDA-MB-453 CVCL: CVCL_0418 EFO: EFO_0001215 ZN MDA-MB-468 cell ATCC: HTB-132 LCL-1471 MDA-MB-468 CHEMBL: CHEMBL3308424 CVCL: CVCL_0419 EFO: EFO_0001216 disease: adenocarcinoma (mammary gland primary) ME-180 cell disease: epidermoid carcinoma (cervix primary) CVCL: CVCL_1401 CHEMBL: CHEMBL3308114 LCL-1305 ATCC: HTB-33 ME-180 MEG-01 cell CVCL: CVCL_0425 MEG-01 LCL-1110 ATCC: CRL-2021 disease: megakaryoblast; chronic myelogenous leukemia CHEMBL: CHEMBL3308539 MEL-HO cell CVCL: CVCL_1402 CHEMBL: CHEMBL3308798 LCL-1251 DSMZ: ACC 62 disease: melanoma MEL-HO HyperCLDB: cl3439 MEL-JUSO cell CVCL: CVCL_1403 LCL-1252 DSMZ: ACC 74 CHEMBL: CHEMBL3308761 MEL-JUSO HyperCLDB: cl3440 MES-SA cell ECACC: 95051030 ATCC: CRL-1976 MES-SA LCL-1509 CVCL: CVCL_1404 CHEMBL: CHEMBL3307599 EFO: EFO_0002233 disease: uterine sarcoma MEWO cell MEWO ECACC: 93082609 HyperCLDB: cl3456 LCL-1253 disease: malignant melanoma MFE-280 cell CVCL: CVCL_1405 MFE-280 HyperCLDB: cl5080 CHEMBL: CHEMBL3308455 ZN LCL-1500 DSMZ: ACC 410 MFE-296 cell CVCL: CVCL_1406 CHEMBL: CHEMBL3308374 MFE-296 LCL-1501 HyperCLDB: cl5323 DSMZ: ACC 419 MFE-319 cell HyperCLDB: cl5324 DSMZ: ACC 423 LCL-1502 MFE-319 MFM-223 cell CVCL: CVCL_1408 HyperCLDB: cl5325 DSMZ: ACC 422 MFM-223 LCL-1318 CHEMBL: CHEMBL3308115 MG-63 cell MG-63 ATCC: CRL-1427 LCL-1428 ECACC: 86051601 MHH-CALL-2 cell HyperCLDB: cl5328 LCL-1009 CHEMBL: CHEMBL3308333 disease: leukemia, pre-B cell CVCL: CVCL_1409 COSMIC ID:908132 MHH-CALL-2 MHH-ES-1 cell HyperCLDB: cl3478 MHH-ES-1 LCL-1454 DSMZ: ACC 167 CHEMBL: CHEMBL3308762 ZN CVCL: CVCL_1411 MHH-NB-11 cell MHH-NB-11 HyperCLDB: cl3479 DSMZ: ACC 157 LCL-1975 CHEMBL: CHEMBL3308310 CVCL: CVCL_1412 MHH-PREB-1 cell MHH-PREB-1 CHEMBL: CHEMBL3308334 CVCL: CVCL_1413 DSMZ: ACC 354 LCL-1140 HyperCLDB: cl5331 disease: B-cell lymphocytic neoplasm,non-Hodgkin lymphoma MIA PaCa-2 cell ATCC: CRL-1420 HyperCLDB: cl3482 CVCL: CVCL_0428 EFO: EFO_0002236 LCL-1738 CHEMBL: CHEMBL3308500 MIA PaCa-2 MJ cell ATCC: CRL-8294 disease: cutaneous T cell lymphoma,non-Hodgkin lymphoma LCL-1142 MJ ML-1 cell LCL-1679 ML-1 disease: leukemia, acute myelogenous DSMZ: ACC 464 HyperCLDB: cl3489 ML-2 cell DSMZ: ACC 15 EFO: EFO_0002238 CVCL: CVCL_1418 LCL-1060 HyperCLDB: cl3490 CHEMBL: CHEMBL3307604 ML-2 disease: leukemia, acute myelomonocytic MN-60 cell CHEMBL: CHEMBL3308532 disease: leukemia, B cell LCL-1010 CVCL: CVCL_1421 COSMIC ID:908143 HyperCLDB: cl3506 MN-60 MOG-G-CCM cell ECACC: 86022702 MOG-G-CCM LCL-1396 disease: astrocytoma, anaplastic CHEMBL: CHEMBL3308456 CVCL: CVCL_2613 HyperCLDB: cl3512 MOG-G-UVW cell disease: astrocytoma, anaplastic ECACC: 86022703 HyperCLDB: cl3513 MOG-G-UVW LCL-1397 CHEMBL: CHEMBL3308137 CVCL: CVCL_2614 MOLT-14 cell LCL-2061 HyperCLDB: cl5334 ACC 437 MOLT-14 disease: leukemia, T cell MOLT-16 cell LCL-1018 DSMZ: ACC 29 CHEMBL: CHEMBL3308271 HyperCLDB: cl3516 CVCL: CVCL_1424 MOLT-16 disease: leukemia, T cell MOLT-4 cell MOLT-4 LCL-1019 ATCC: CRL-1582 CVCL: CVCL_0013 CHEMBL: CHEMBL3307557 EFO: EFO_0001220 disease: acute lymphoblastic leukemia MONO-MAC-1 cell LCL-1062 MONO-MAC-1 HyperCLDB: cl3534 DSMZ: ACC 252 disease: leukemia, acute monocytic MONO-MAC-6 cell CHEMBL: CHEMBL3308335 DSMZ: ACC 124 LCL-1063 CVCL: CVCL_1426 WEB: http://bioinformatics.hsanmartino.it/cldb/cl3535.html HyperCLDB: cl3535 MONO-MAC-6 disease: leukemia, acute monocytic MS751 cell LCL-1306 ATCC: HTB-34 MS751 disease: epidermoid carcinoma (cervix primary) MSTO-211H cell EFO: EFO_0002839 ATCC: CRL-2081 LCL-1776 CHEMBL: CHEMBL3308116 disease: mesothelioma, biphasic (lung primary) CVCL: CVCL_1430 MSTO-211H MT-3 cell HyperCLDB: cl5337 DSMZ: ACC 403 MT-3 LCL-1473 MV-4-11 cell disease: biphenotypic B myelo- monocytic leukemia MV-4-11 CRL-9591 LCL-1092 ATCC: CRL-9591 HyperCLDB: cl3611 HyperCLDB: cl3610 NALM-6 cell CHEMBL: CHEMBL3307559 NALM-6 disease: leukemia, acute lymphoblastic pre-B cell LCL-1007 HyperCLDB: cl3631 ACC 128 EFO: EFO_0002245 CVCL: CVCL_0092 NAMALWA cell HyperCLDB: cl3633 LCL-2022 disease: Burkitts lymphoma NAMALWA ATCC: CRL-1432 NAMALWA.PNT cell HyperCLDB: cl3641 DSMZ: ACC 69 NAMALWA.PNT LCL-2029 NB-4 cell CVCL: CVCL_0005 EFO: EFO_0002798 ACC 207 LCL-1084 HyperCLDB: cl3643 CHEMBL: CHEMBL3308423 NB-4 disease: leukemia,acute promyelocytic NC-37 cell ATCC: CCL-214 NC-37 LCL-2057 CVCL: CVCL_3042 CHEMBL: CHEMBL3307322 EFO: EFO_0002247 NCI-H1048 cell disease: carcinoma; small cell lung cancer (lung primary) CHEMBL: CHEMBL3308763 EFO: EFO_0002248 LCL-1810 NCI-H1048 CVCL: CVCL_1453 ATCC: CRL-5853 NCI-H1092 cell LCL-1836 ATCC: CRL-5855 disease: carcinoma; classic small cell lung cancer (lung primary) CHEMBL: CHEMBL3308311 EFO: EFO_0002249 NCI-H1092 CVCL: CVCL_1454 NCI-H1155 cell ZN LCL-1628 ATCC: CRL-5818 CVCL: CVCL_1456 NCI-H1155 EFO: EFO_0002250 CHEMBL: CHEMBL3308312 disease: large cell neuro- endocrine carcinoma (lung primary) NCI-H1299 cell EFO: EFO_0003043 ATCC: CRL-5803 CHEMBL: CHEMBL3308501 disease: large cell neuro- endocrine carcinoma (lung primary) ZN LCL-1609 NCI-H1299 CVCL: CVCL_0060 NCI-H1304 cell ATCC: CRL-5862 CVCL: CVCL_1462 NCI-H1304 disease: carcinoma; classic small cell lung cancer (lung primary) LCL-2058 CHEMBL: CHEMBL3308554 NCI-H1355 cell ATCC: CRL-5865 EFO: EFO_0002251 LCL-1669 ZN CHEMBL: CHEMBL3308876 NCI-H1355 CVCL: CVCL_1464 Sanger: COSMIC ID:724866 disease: adenocarcinoma (lung primary) NCI-H1385 cell ZN ATCC: CRL-5867 disease: squamous cell neuro- endocrine carcinoma (lung primary) NCI-H1385 LCL-1624 NCI-H1395 cell NCI-H1395 EFO: EFO_0002252 CVCL: CVCL_1467 ATCC: CRL-5868 LCL-1660 CHEMBL: CHEMBL3308313 NCI-H1404 cell NCI-H1404 disease: papillary adenocar- cinoma (lung primary) ATCC: CRL-5819 LCL-1912 NCI-H1417 cell ATCC: CRL-5869 NCI-H1417 CHEMBL: CHEMBL3308854 disease: carcinoma; classic small cell lung cancer CVCL: CVCL_1469 LCL-1837 NCI-H1435 cell ATCC: CRL-5870 LCL-1610 disease: adenocarcinoma; non-small cell lung cancer NCI-H1435 NCI-H1436 cell CVCL: CVCL_1471 LCL-1838 ATCC: CRL-5871 EFO: EFO_0002253 NCI-H1436 CHEMBL: CHEMBL3308893 disease: carcinoma; classic small cell lung cancer (lung primary) NCI-H1437 cell ATCC: CRL-5872 LCL-1637 ZN disease: adenocarcinoma; non-small cell lung cancer (lung primary) CVCL: CVCL_1472 NCI-H1437 CHEMBL: CHEMBL3308764 EFO: EFO_0002254 NCI-H1522 cell LCL-1839 NCI-H1522 CVCL: CVCL_1474 disease: carcinoma; small cell lung cancer (lung primary) ATCC: CRL-5874 CHEMBL: CHEMBL3308877 NCI-H1563 cell NCI-H1563 LCL-1661 ATCC: CRL-5875 CVCL: CVCL_1475 EFO: EFO_0002255 CHEMBL: CHEMBL3308457 disease: adenocarcinoma; non-small cell lung cancer NCI-H1568 cell LCL-1611 ATCC: CRL-5876 disease: adenocarcinoma; non-small cell lung cancer (lung primary) ZN NCI-H1568 NCI-H1573 cell LCL-1638 CVCL: CVCL_1478 ATCC: CRL-5877 disease: adenocarcinoma (lung primary) EFO: EFO_0002256 CHEMBL: CHEMBL3308117 ZN NCI-H1573 NCI-H1581 cell CVCL: CVCL_1479 EFO: EFO_0002257 ATCC: CRL-5878 disease: large cell adenocarcinoma; non-small cell lung cancer CHEMBL: CHEMBL3308765 LCL-1783 NCI-H1581 NCI-H1618 cell ATCC: CRL-5879 LCL-1840 EFO: EFO_0002258 NCI-H1618 CHEMBL: CHEMBL3308314 disease: carcinoma; small cell lung cancer (lung primary) CVCL: CVCL_1480 NCI-H1623 cell ATCC: CRL-5881 EFO: EFO_0002259 disease: adenocarcinoma; non-small cell lung cancer (lung primary) LCL-1639 CVCL: CVCL_1481 NCI-H1623 ZN CHEMBL: CHEMBL3308766 NCI-H1648 cell ZN NCI-H1648 ATCC: CRL-5882 LCL-1632 disease: adenocarcinoma (lung primary) CHEMBL: CHEMBL3308315 CVCL: CVCL_1482 EFO: EFO_0003119 NCI-H1650 cell EFO: EFO_0002260 CHEMBL: CHEMBL3308800 disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) LCL-1612 CVCL: CVCL_1483 ATCC: CRL-5883 NCI-H1650 ZN NCI-H1651 cell EFO: EFO_0002261 CHEMBL: CHEMBL3308383 CVCL: CVCL_1484 LCL-1633 disease: adenocarcinoma; non-small cell lung cancer ATCC: CRL-5884 NCI-H1651 NCI-H1666 cell NCI-H1666 CHEMBL: CHEMBL3308118 LCL-1673 EFO: EFO_0002262 CVCL: CVCL_1485 ZN ATCC: CRL-5885 disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) NCI-H1688 cell ATCC: CCL-257 disease: carcinoma; classic small cell lung cancer LCL-1811 NCI-H1688 NCI-H1693 cell LCL-1640 NCI-H1693 ATCC: CRL-5887 CHEMBL: CHEMBL3308458 ZN disease: adenocarcinoma; non-small cell lung cancer (lung primary) CVCL: CVCL_1488 NCI-H1694 cell CHEMBL: CHEMBL3308555 NCI-H1694 ATCC: CRL-5888 EFO: EFO_0002263 CVCL: CVCL_1489 disease: carcinoma; classic small cell lung cancer (lung primary) LCL-1841 NCI-H1703 cell CHEMBL: CHEMBL3308503 disease: squamous cell adenocarcinoma; non-small cell lung cancer LCL-1582 ATCC: CRL-5889 EFO: EFO_0002264 CVCL: CVCL_1490 NCI-H1703 NCI-H1734 cell LCL-1641 NCI-H1734 ATCC: CRL-5891 disease: adenocarcinoma; non-small cell lung cancer CVCL: CVCL_1491 CHEMBL: CHEMBL3308767 NCI-H1755 cell LCL-1642 CHEMBL: CHEMBL3308768 NCI-H1755 ATCC: CRL-5892 CVCL: CVCL_1492 ZN disease: adenocarcinoma; non-small cell lung cancer (lung primary) NCI-H1770 cell NCI-H1770 disease: neuroendocrine carc- cinoma; non-small cell lung cancer (lung primary) CVCL: CVCL_1493 LCL-1625 ZN CHEMBL: CHEMBL3308316 EFO: EFO_0002265 ATCC: CRL-5893 NCI-H1781 cell disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) LCL-1643 ATCC: CRL-5894 ZN NCI-H1781 NCI-H1792 cell CHEMBL: CHEMBL3308816 ATCC: CRL-5895 ZN disease: adenocarcinoma (lung primary) CVCL: CVCL_1495 EFO: EFO_0002266 LCL-1644 NCI-H1792 NCI-H1793 cell LCL-1645 CVCL: CVCL_1496 disease: adenocarcinoma; non-small cell lung cancer ATCC: CRL-5896 EFO: EFO_0002267 CHEMBL: CHEMBL3308579 NCI-H1793 NCI-H1836 cell ATCC: CRL-5898 NCI-H1836 disease: carcinoma; classic small cell lung cancer LCL-1842 NCI-H1838 cell LCL-1662 disease: adenocarcinoma; non-small cell lung cancer CVCL: CVCL_1499 ATCC: CRL-5899 NCI-H1838 EFO: EFO_0002268 CHEMBL: CHEMBL3308317 NCI-H1869 cell LCL-1613 ZN disease: squamous cell carcinoma (lung primary) NCI-H1869 ATCC: CRL-5900 NCI-H187 cell ATCC: CRL-5804 NCI-H187 EFO: EFO_0002269 CVCL: CVCL_1501 disease: carcinoma; classic small cell lung cancer (lung primary) CHEMBL: CHEMBL3308878 LCL-1843 NCI-H1876 cell LCL-1812 disease: carcinoma; classic small cell lung cancer (lung primary) NCI-H1876 ATCC: CRL-5902 NCI-H1882 cell CVCL: CVCL_1504 ATCC: CRL-5903 CHEMBL: CHEMBL3308318 disease: carcinoma; small cell lung cancer (lung primary) NCI-H1882 LCL-1844 NCI-H1915 cell ATCC: CRL-5904 ZN LCL-1598 disease: large cell carcinoma; poorly differentiated (lung primary) NCI-H1915 NCI-H1944 cell LCL-1614 ZN NCI-H1944 disease: adenocarcinoma; non-small cell lung cancer (lung primary) ATCC: CRL-5907 NCI-H196 cell LCL-1813 disease: carcinoma; variant small cell lung cancer (lung primary) NCI-H196 ATCC: CRL-5823 NCI-H1963 cell CVCL: CVCL_1510 NCI-H1963 CHEMBL: CHEMBL3308855 LCL-1845 ATCC: CRL-5982 disease: carcinoma; small cell lung cancer NCI-H1975 cell LCL-1663 ATCC: CRL-5908 EFO: EFO_0002271 CVCL: CVCL_1511 disease: adenocarcinoma; non-small cell lung cancer NCI-H1975 CHEMBL: CHEMBL3307601 NCI-H1993 cell EFO: EFO_0002272 ATCC: CRL-5909 ZN CHEMBL: CHEMBL3308138 LCL-1646 disease: adenocarcinoma; non-small cell lung cancer (lung primary) CVCL: CVCL_1512 NCI-H1993 NCI-H2009 cell ATCC: CRL-5911 NCI-H2009 LCL-1647 disease: adenocarcinoma (lung primary) CVCL: CVCL_1514 CHEMBL: CHEMBL3308459 ZN EFO: EFO_0002273 NCI-H2023 cell NCI-H2023 ATCC: CRL-5912 disease: adenocarcinoma; non-small cell lung cancer (lung primary) ZN LCL-1599 NCI-H2029 cell disease: carcinoma; small cell lung cancer (lung primary) CHEMBL: CHEMBL3308473 NCI-H2029 ATCC: CRL-5913 LCL-1814 CVCL: CVCL_1516 NCI-H2030 cell ZN EFO: EFO_0002274 ATCC: CRL-5914 NCI-H2030 CVCL: CVCL_1517 CHEMBL: CHEMBL3308769 LCL-1648 disease: adenocarcinoma; non-small cell lung cancer (lung primary) NCI-H2073 cell disease: adenocarcinoma; non-small cell lung cancer NCI-H2073 LCL-1649 ATCC: CRL-5918 NCI-H2081 cell EFO: EFO_0002276 CHEMBL: CHEMBL3308319 LCL-1846 CVCL: CVCL_1522 ATCC: CRL-5920 NCI-H2081 disease: carcinoma; classic small cell lung cancer (lung primary) NCI-H2085 cell disease: adenocarcinoma; non-small cell lung cancer ATCC: CRL-5921 LCL-1615 NCI-H2085 NCI-H2087 cell disease: adenocarcinoma; non-small cell lung cancer (lung primary) ZN ATCC: CRL-5922 LCL-1650 EFO: EFO_0002277 CHEMBL: CHEMBL3308770 NCI-H2087 CVCL: CVCL_1524 NCI-H209 cell CHEMBL: CHEMBL3308293 ATCC: HTB-172 disease: carcinoma; small cell lung cancer (lung primary) CVCL: CVCL_1525 NCI-H209 LCL-1847 NCI-H2106 cell disease: large cell neuro- endocrine carcinoma (lung primary) NCI-H2106 ATCC: CRL-5923 LCL-1848 NCI-H211 cell ATCC: CRL-5824 NCI-H211 LCL-1849 disease: carcinoma; small cell lung cancer (lung primary) NCI-H2110 cell LCL-1616 ZN NCI-H2110 disease: non-small cell lung cancer (lung primary) ATCC: CRL-5924 NCI-H2122 cell CVCL: CVCL_1531 NCI-H2122 EFO: EFO_0002279 disease: adenocarcinoma; non-small cell lung cancer (lung primary) LCL-1651 ATCC: CRL-5985 CHEMBL: CHEMBL3308771 ZN NCI-H2126 cell NCI-H2126 Sanger: COSMIC ID:687814 EFO: EFO_0002280 ATCC: CCL-256 CHEMBL: CHEMBL3308894 LCL-1627 CVCL: CVCL_1532 disease: carcinoma; non-small cell lung cancer NCI-H2135 cell disease: non-small cell lung cancer LCL-1617 ATCC: CRL-5926 NCI-H2135 NCI-H2141 cell LCL-1850 ATCC: CRL-5927 disease: carcinoma; small cell lung cancer (lung primary) CVCL: CVCL_1534 CHEMBL: CHEMBL3308556 NCI-H2141 NCI-H2170 cell LCL-1590 disease: squamous cell carcinoma CVCL: CVCL_1535 NCI-H2170 ATCC: CRL-5928 EFO: EFO_0002281 CHEMBL: CHEMBL3308460 NCI-H2171 cell disease: carcinoma; small cell lung cancer (lung primary) CVCL: CVCL_1536 CHEMBL: CHEMBL3308320 ATCC: CRL-5929 EFO: EFO_0002282 NCI-H2171 LCL-1851 NCI-H2172 cell LCL-1618 NCI-H2172 disease: non-small cell lung cancer ATCC: CRL-5930 NCI-H2195 cell ATCC: CRL-5931 disease: carcinoma; small cell lung cancer (lung primary) LCL-1815 NCI-H2195 NCI-H2196 cell CHEMBL: CHEMBL3308772 LCL-1816 CVCL: CVCL_1539 ATCC: CRL-5932 NCI-H2196 disease: carcinoma; small cell lung cancer (lung primary) NCI-H2198 cell LCL-1817 disease: carcinoma; small cell lung cancer (lung primary) NCI-H2198 ATCC: CRL-5933 NCI-H220 cell LCL-1852 NCI-H220 disease: carcinoma; classic small cell lung cancer (lung primary) ATCC: CRL-5825 NCI-H2227 cell CHEMBL: CHEMBL3308321 NCI-H2227 disease: carcinoma; small cell lung cancer ATCC: CRL-5934 LCL-1853 CVCL: CVCL_1542 NCI-H2228 cell CHEMBL: CHEMBL3308120 CVCL: CVCL_1543 ATCC: CRL-5935 LCL-1652 disease: adenocarcinoma; non-small cell lung cancer EFO: EFO_0002284 NCI-H2228 NCI-H226 cell ATCC: CRL-5826 CHEMBL: CHEMBL3307697 LCL-1597 disease: squamous cell carcinoma; mesothelioma (lung primary) NCI-H226 CVCL: CVCL_1544 EFO: EFO_0002285 ZN NCI-H2286 cell ATCC: CRL-5938 disease: small cell lung cancer; adeno- carcinoma; squamous cell carcinoma LCL-1818 NCI-H2286 NCI-H2291 cell CHEMBL: CHEMBL3308880 ATCC: CRL-5939 LCL-1653 NCI-H2291 CVCL: CVCL_1546 ZN disease: adenocarcinoma; non-small cell lung cancer (lung primary) NCI-H23 cell ATCC: CRL-5800 EFO: EFO_0002286 disease: adenocarcinoma; non-small cell lung cancer CHEMBL: CHEMBL3307750 CVCL: CVCL_1547 LCL-1619 NCI-H23 NCI-H2342 cell ATCC: CRL-5941 disease: adenocarcinoma; non-small cell lung cancer CHEMBL: CHEMBL3308773 LCL-1654 CVCL: CVCL_1549 NCI-H2342 NCI-H2347 cell EFO: EFO_0002287 CHEMBL: CHEMBL3308386 ATCC: CRL-5942 NCI-H2347 disease: adenocarcinoma; non-small cell lung cancer LCL-1620 CVCL: CVCL_1550 NCI-H2405 cell ATCC: CRL-5944 disease: adenocarcinoma; non-small cell lung cancer (lung primary) CHEMBL: CHEMBL3308774 LCL-1655 CVCL: CVCL_1551 EFO: EFO_0002288 NCI-H2405 ZN NCI-H2444 cell NCI-H2444 ATCC: CRL-5945 LCL-1621 disease: non-small cell lung cancer NCI-H2452 cell NCI-H2452 ATCC: CRL-5946 CVCL: CVCL_1553 LCL-1230 disease: mesothelioma CHEMBL: CHEMBL3308580 NCI-H322 cell LCL-1798 ECACC: 95111734 disease: carcinoma, bronchioalveolar NCI-H322 HyperCLDB: cl3655 NCI-H345 cell CVCL: CVCL_1558 NCI-H345 disease: carcinoma; small cell lung cancer (lung primary) ATCC: HTB-180 CHEMBL: CHEMBL3307324 LCL-1854 NCI-H358 cell disease: alveolus); bronchioalveolar carcinoma; non-small cell lung cancer LCL-1671 EFO: EFO_0002291 CVCL: CVCL_1559 ATCC: CRL-5807 CHEMBL: CHEMBL3307543 ZN NCI-H358 NCI-H441 cell disease: papillary adeno- carcinoma (lung primary) CVCL: CVCL_1561 NCI-H441 EFO: EFO_0002292 CHEMBL: CHEMBL3308121 LCL-1911 ATCC: HTB-174 NCI-H446 cell LCL-1855 CHEMBL: CHEMBL3307760 NCI-H446 EFO: EFO_0002293 CVCL: CVCL_1562 ATCC: HTB-171 disease: carcinoma; small cell lung cancer (lung primary) NCI-H460 cell LCL-1784 disease: large cell carci- noma (lung primary) CHEMBL: CHEMBL3307677 EFO: EFO_0003044 NCI-H460 CVCL: CVCL_0459 QL, YH ATCC: HTB-177 NCI-H510A cell NCI-H510A LCL-1856 CVCL: CVCL_1565 disease: carcinoma; small cell lung cancer (unknown primary) CHEMBL: CHEMBL3308322 ATCC: HTB-184 NCI-H520 cell LCL-1591 disease: squamous cell carcinoma ATCC: HTB-182 NCI-H520 NCI-H522 cell EFO: EFO_0002295 NCI-H522 LCL-1622 CVCL: CVCL_1567 ATCC: CRL-5810 CHEMBL: CHEMBL3308392 disease: adenocarcinoma; non-small cell lung cancer NCI-H524 cell ATCC: CRL-5831 EFO: EFO_0002296 NCI-H524 CVCL: CVCL_1568 disease: carcinoma; variant small cell lung cancer (lung primary) LCL-1857 CHEMBL: CHEMBL3308296 NCI-H526 cell LCL-1858 CHEMBL: CHEMBL3308881 disease: carcinoma; classic small cell lung cancer (lung primary) ATCC: CRL-5811 NCI-H526 CVCL: CVCL_1569 NCI-H596 cell disease: adenosquamous carcinoma NCI-H596 ATCC: HTB-178 LCL-1786 NCI-H630 cell CHEMBL: CHEMBL3307966 disease: carcinoma (rectum primary) EFO: EFO_0002297 LCL-1287 NCI-H630 ATCC: CRL-5833 CVCL: CVCL_1572 NCI-H647 cell disease: mixed adeno- squamous and carcinoma (lung primary) LCL-1629 ATCC: CRL-5834 NCI-H647 ZN NCI-H650 cell LCL-1672 ATCC: CRL-5835 EFO: EFO_0002298 disease: bronchioalveolar carci- noma; non-small cell lung cancer (lung primary) NCI-H650 CVCL: CVCL_1575 CHEMBL: CHEMBL3308461 ZN NCI-H661 cell disease: carcinoma; large cell lung cancer (lung primary) ATCC: HTB-183 EFO: EFO_0002299 CHEMBL: CHEMBL3308139 CVCL: CVCL_1577 NCI-H661 LCL-1785 NCI-H69 cell CVCL: CVCL_1579 LCL-1859 NCI-H69 ATCC: HTB-119 disease: carcinoma; small cell lung cancer (lung primary) CHEMBL: CHEMBL3307712 EFO: EFO_0002823 NCI-H716 cell ATCC: CCL-251 LCL-1339 CVCL: CVCL_1581 CHEMBL: CHEMBL3308297 disease: colorectal adenocarcinoma Sanger: COSMIC ID:908458 NCI-H716 EFO: EFO_0002301 NCI-H719 cell CHEMBL: CHEMBL3308551 CVCL: CVCL_1582 NCI-H719 LCL-1860 ATCC: CRL-5837 disease: carcinoma; classic small cell lung cancer (lung primary) NCI-H720 cell CHEMBL: CHEMBL3308851 disease: atypical carcinoid EFO: EFO_0002302 NCI-H720 ATCC: CRL-5838 LCL-1155 CVCL: CVCL_1583 NCI-H727 cell ATCC: CRL-5815 disease: carcinoid CHEMBL: CHEMBL3308393 LCL-1153 CVCL: CVCL_1584 NCI-H727 NCI-H747 cell NCI-H747 CHEMBL: CHEMBL3308895 LCL-1340 EFO: EFO_0002303 ATCC: CCL-252 disease: colorectal adenocarcinoma CVCL: CVCL_1587 Sanger: COSMIC ID:908457 NCI-H748 cell CHEMBL: CHEMBL3308298 NCI-H748 ATCC: CRL-5841 LCL-1861 EFO: EFO_0002304 disease: carcinoma; classic small cell lung cancer (lung primary) CVCL: CVCL_1588 NCI-H810 cell EFO: EFO_0002305 ATCC: CRL-5816 disease: large cell; neuroendocrine; carcinoma; non-small cell lung cancer CHEMBL: CHEMBL3308483 LCL-1670 CVCL: CVCL_1590 NCI-H810 NCI-H82 cell ATCC: HTB-175 CHEMBL: CHEMBL3308882 LCL-1862 EFO: EFO_0002306 CVCL: CVCL_1591 disease: carcinoma; small cell lung cancer (lung primary) NCI-H82 NCI-H838 cell EFO: EFO_0002307 disease: adenocarcinoma; non- small cell lung cancer (lung primary) LCL-1623 NCI-H838 CVCL: CVCL_1594 CHEMBL: CHEMBL3308122 ZN ATCC: CRL-5844 NCI-H841 cell LCL-1819 ATCC: CRL-5845 disease: carcinoma; variant small cell lung cancer (lung primary) NCI-H841 NCI-H847 cell NCI-H847 disease: carcinoma; classic small cell lung cancer (lung primary) LCL-1863 ATCC: CRL-5846 NCI-H889 cell NCI-H889 ATCC: CRL-5817 CVCL: CVCL_1598 LCL-1864 CHEMBL: CHEMBL3308299 disease: carcinoma; classic small cell lung cancer (lung primary) NCI-N87 cell NCI-N87 CHEMBL: CHEMBL3307326 EFO: EFO_0002841 disease: gastric carcinoma (stomach primary) LCL-1886 CVCL: CVCL_1603 ATCC: CRL-5822 NIH:OVCAR-3 cell disease: adenocarcinoma (ovary primary) NIH:OVCAR-3 LCL-1522 ATCC: HTB-161 ZN NK-92MI cell disease: IL-2 independent, cytotoxic to a wide range of malignant cells NK-92MI LCL-1127 ATCC: CRL-2408 OAW28 cell HyperCLDB: cl3756 OAW28 LCL-1698 ECACC: 85101601 OAW42 cell disease: cystoadenocarcinoma ECACC: 85073102 OAW42 HyperCLDB: cl3757 LCL-1699 OCI-AML2 cell OCI-AML2 HyperCLDB: cl3760 CVCL: CVCL_1619 DSMZ: ACC 99 CHEMBL: CHEMBL3308300 LCL-1065 disease: leukemia, acute myeloid OCI-AML5 cell DSMZ: ACC 247 OCI-AML5 disease: leukemia, acute myeloid LCL-1067 HyperCLDB: cl5342 OE19 cell CHEMBL: CHEMBL3308462 HyperCLDB: cl3761 CVCL: CVCL_1622 ECACC: 96071721 OE19 LCL-1796 EFO: EFO_0002308 OE21 cell ZN ECACC: 96062201 LCL-1558 HyperCLDB: cl5089 OE21 OE33 cell OE33 ECACC: 96070808 HyperCLDB: cl3762 CHEMBL: CHEMBL3308776 CVCL: CVCL_0471 EFO: EFO_0002310 LCL-1797 OPM-2 cell OPM-2 HyperCLDB: cl3774 CHEMBL: CHEMBL3308883 CVCL: CVCL_1625 LCL-2048 DSMZ: ACC 50 OV-90 cell OV-90 disease: malignant papillary serous adenocarcinoma (ovary primary) ATCC: CRL-11732 LCL-1523 P116.cl39 cell disease: transfected with ZAP-70 expression vector; control for P116 cells LCL-1032 ATCC: CRL-2677 P116.cl39 P12-ICHIKAWA cell HyperCLDB: cl3807 CHEMBL: CHEMBL3307676 P12-ICHIKAWA DSMZ: ACC 34 LCL-1020 disease: acute T cell leukemia CVCL: CVCL_1630 P3HR-1 cell disease: Burkitts lymphoma; B lymphoblast LCL-2024 CVCL: CVCL_2676 CHEMBL: CHEMBL3307242 ATCC: HTB-62 EFO: EFO_0002312 P3HR-1 PA-1 cell ZN CHEMBL: CHEMBL3308812 CVCL: CVCL_0479 ATCC: CRL-1572 PA-1 LCL-1416 disease: teratocarcinoma (ovary primary) Panc 02.03 cell Panc 02.03 LCL-1739 ATCC: CRL-2553 Panc 03.27 cell Panc 03.27 ATCC: CRL-2549 LCL-1740 Panc 04.03 cell Panc 04.03 LCL-1741 ATCC: CRL-2555 Panc 08.13 cell ATCC: CRL-2551 Panc 08.13 LCL-1742 Panc 10.05 cell Panc 10.05 ATCC: CRL-2547 disease: adenocarcinoma; same patient as PL45 LCL-1743 PANC-1 cell ATCC: CRL-1469 disease: epithelioid carcinoma CHEMBL: CHEMBL3307545 CVCL: CVCL_0480 LCL-1726 EFO: EFO_0002713 PANC-1 PA-TU-8902 cell DSMZ: ACC 179 LCL-1744 HyperCLDB: cl3860 PA-TU-8902 PA-TU-8988S cell HyperCLDB: cl3861 PA-TU-8988S DSMZ: ACC 204 LCL-1745 PA-TU-8988T cell LCL-1746 HyperCLDB: cl3862 DSMZ: ACC 162 PA-TU-8988T PC-14 cell CVCL: CVCL_1640 PC-14 EFO: EFO_0002844 HyperCLDB: cl3880 CHEMBL: CHEMBL3307306 LCL-1656 ECACC: 90071810 PC-3 cell ATCC: CRL-1435 disease: adenocarcinoma (prostate primary) CVCL: CVCL_0035 CHEMBL: CHEMBL3307570 PC-3 EFO: EFO_0002074 LCL-1299 PEER cell PEER disease: leukemia, T cell ACC 6 LCL-2062 HyperCLDB: cl4115 PF-382 cell HyperCLDB: cl3895 LCL-1021 disease: acute T cell leukemia DSMZ: ACC 38 PF-382 CVCL: CVCL_1641 CHEMBL: CHEMBL3308246 Pfeiffer cell Pfeiffer disease: diffuse large cell non-Hodgkins lymphoma (B lymphocyte primary) LCL-1122 ATCC: CRL-2632 PFSK-1 cell disease: malignant primitive neuroectodermal tumor ZN PFSK-1 CHEMBL: CHEMBL3308802 CVCL: CVCL_1642 ATCC: CRL-2060 EFO: EFO_0005234 LCL-1407 PL45 cell LCL-1727 PL45 ATCC: CRL-2558 disease: ductal adenocarcinoma; same patient as Panc 10.05 cells PLC/PRF/5 cell PLC/PRF/5 ATCC: CRL-8024 LCL-1942 disease: hepatoma ECACC: 85061113 PSN1 cell HyperCLDB: cl3949 CHEMBL: CHEMBL3307348 ECACC: 94060601,94060601; COSMIC ID:910546 CVCL: CVCL_1644 LCL-1749 PSN1 QIMR-WIL cell CHEMBL: CHEMBL3308301 CVCL: CVCL_1645 Sanger: COSMIC ID:910545 disease: leukemia, myeloblastic QIMR-WIL HyperCLDB: cl4042 LCL-1075 Raji cell LCL-2025 CHEMBL: CHEMBL3307663 disease: Burkitts lymphoma EFO: EFO_0002324 Raji HyperCLDB: cl4091 HyperCLDB: cl4092 ATCC: CCL-86 CVCL: CVCL_0511 Ramos (RA 1) cell LCL-1097 Ramos (RA 1) HyperCLDB: cl4098 ATCC: CRL-1596 disease: Burkitts lymphoma (American) RD cell CVCL: CVCL_1649 ZN EFO: EFO_0002315 CHEMBL: CHEMBL3307547 disease: rhabdomyosarcoma RD ATCC: CCL-136 LCL-1411 RD-ES cell ATCC: HTB-166 RD-ES disease: Ewings sarcoma LCL-1455 REH cell HyperCLDB: cl4132 REH disease: leukemia, pre-B cell LCL-1039 CVCL: CVCL_1650 ATCC: CRL-8286 CHEMBL: CHEMBL3308823 Reh cell Reh LCL-1039 ATCC: CRL-8286 disease: acute lymphocytic leukemia (non-T, non-B) RKO cell Sanger: COSMIC ID:909698 RKO LCL-1168 EFO: EFO_0001232 disease: carcinoma; control for RKO-E6 and RKO-AS45-1 cells CHEMBL: CHEMBL3307731 CVCL: CVCL_0504 ATCC: CRL-2577 RL cell CVCL: CVCL_1660 LCL-1133 disease: non-Hodgkins lymphoma; B lymphoblast RL EFO: EFO_0002319 CHEMBL: CHEMBL3308515 ATCC: CRL-2261 RL95-2 cell ATCC: CRL-1671,COSMIC ID:930082; ATCC CRL-1671 ZN CVCL: CVCL_0505 CHEMBL: CHEMBL3308843 RL95-2 LCL-1506 ATCC: CRL-1671 RO82-W-1 cell CHEMBL: CHEMBL3308779 CVCL: CVCL_0582 ECACC: 92030502 LCL-1680 HyperCLDB: cl4167 RO82-W-1 RPMI 2650 cell RPMI 2650 LCL-1881 ATCC: CCL-30 disease: squamous cell carcinoma (nasal septum primary) RPMI 6666 cell ATCC: CCL-113 CCL-113 disease: Hodgkins disease RPMI 6666 LCL-2013 RPMI 8226 cell disease: plasmacytoma; myeloma RPMI 8226 LCL-2049 ATCC: CCL-155 HyperCLDB: cl5355 RPMI-7951 cell LCL-1254 disease: malignant melanoma RPMI-7951 CHEMBL: CHEMBL3307962 ATCC: HTB-66 CVCL: CVCL_1666 RS4;11 cell RS4;11 LCL-1040 disease: acute lymphoblastic leukemia; t(4;11) translocation ATCC: CRL-1873 RT-112 cell LCL-1716 HyperCLDB: cl5357 RT-112 CVCL: CVCL_1670 CHEMBL: CHEMBL3307307 DSMZ: ACC 418 disease: carcinoma, transitional cell RT112/84 cell RT112/84 LCL-1705 ECACC: 85061106 HyperCLDB: cl4196 RT4 cell HyperCLDB: cl5358 ECACC: 91091914 disease: transitional cell papilloma RT4 ATCC: HTB-2 LCL-1717 RVH-421 cell LCL-1255 RVH-421 HyperCLDB: cl4207 CVCL: CVCL_1672 DSMZ: ACC 127 CHEMBL: CHEMBL3308126 disease: melanoma S-117 cell HyperCLDB: cl4235 DSMZ: ACC 266 CVCL: CVCL_1674 CHEMBL: CHEMBL3308464 S-117 LCL-1777 Saos-2 cell ATCC: HTB-85 LCL-1430 HyperCLDB: cl4251 CHEMBL: CHEMBL3307737 Saos-2 CVCL: CVCL_0548 HyperCLDB: cl4252 SBC-2 cell LCL-1866 HyperCLDB: cl4257 SBC-2 JHSF: JCRB0817 SC-1 cell ATCC: CRL-8756 SC-1 LCL-1944 disease: EBV transformed CRL-8756 SC-1 cell LCL-1944 SC-1 ATCC: CRL-1404 CRL-8756 SC-1 cell SC-1 CRL-8756 LCL-1944 ATCC: CRL-6450 SCaBER cell ATCC: HTB-3 SCaBER LCL-1540 disease: transitional cell carcinoma CVCL: CVCL_3599 EFO: EFO_0002325 CHEMBL: CHEMBL3307437 SCC-15 cell disease: squamous cell carcinoma CVCL: CVCL_1681 LCL-1222 SCC-15 CHEMBL: CHEMBL3307438 ATCC: CRL-1623 SCC-25 cell CHEMBL: CHEMBL3307440 CVCL: CVCL_1682 LCL-1223 SCC-25 ATCC: CRL-1628 disease: squamous cell carcinoma SCC-4 cell CHEMBL: CHEMBL3308803 SCC-4 disease: squamous cell carcinoma ATCC: CRL-1624 CVCL: CVCL_1684 LCL-1224 SCC-9 cell CHEMBL: CHEMBL3308782 ATCC: CRL-1629 SCC-9 CVCL: CVCL_1685 LCL-1225 disease: squamous cell carcinoma SCLC-21H cell CHEMBL: CHEMBL3308465 SCLC-21H CVCL: CVCL_0024 HyperCLDB: cl5361 LCL-1822 DSMZ: ACC 372 disease: carcinoma, small cell SH-4 cell CVCL: CVCL_1692 Sanger: COSMIC ID:909713 LCL-1280 SH-4 ATCC: CRL-7724 CHEMBL: CHEMBL3308177 disease: melanoma (skin primary) SHP-77 cell EFO: EFO_0002328 SHP-77 CVCL: CVCL_1693 disease: carcinoma; small cell lung cancer; large cell variant LCL-1823 ATCC: CRL-2195 CHEMBL: CHEMBL3308363 SH-SY5Y cell SH-SY5Y disease: neuroblastoma (brain primary) LCL-2000 ATCC: CRL-2266 SIG-M5 cell disease: leukemia, acute monocytic SIG-M5 CHEMBL: CHEMBL3308248 CVCL: CVCL_1694 LCL-1071 HyperCLDB: cl7113 DSMZ: ACC 468 SiHa cell CVCL: CVCL_0032 disease: squamous cell carcinoma SiHa CHEMBL: CHEMBL3307968 EFO: EFO_0002379 LCL-1542 ATCC: HTB-35 SIMA cell CVCL: CVCL_1695 LCL-1979 CHEMBL: CHEMBL3308828 HyperCLDB: cl4300 DSMZ: ACC 164 SIMA SISO cell CVCL: CVCL_2193 LCL-1514 CHEMBL: CHEMBL3307272 SISO DSMZ: ACC 327 HyperCLDB: cl5367 SJSA-1 cell SJSA-1 CVCL: CVCL_1697 EFO: EFO_0002330 disease: osteosarcoma; multipotential sarcoma LCL-1433 Sanger: COSMIC ID:909717 CHEMBL: CHEMBL3308885 ATCC: CRL-2098 SK-BR-3 cell CVCL: CVCL_0033 CHEMBL: CHEMBL3308062 EFO: EFO_0001236 SK-BR-3 LCL-1475 ATCC: HTB-30 ZN disease: adenocarcinoma (colon primary) SK-CO-1 cell CVCL: CVCL_0626 CHEMBL: CHEMBL3308784 LCL-1184 SK-CO-1 disease: colorectal adenocarcinoma (colon primary) ATCC: HTB-39 SK-ES-1 cell SK-ES-1 disease: sarcoma (anaplastic osteosarcoma or Ewings sarcoma) LCL-1434 ATCC: HTB-86 SK-HEP-1 cell disease: adenocarcinoma (liver primary) ATCC: HTB-52 LCL-1941 SK-HEP-1 SK-LMS-1 cell SK-LMS-1 ATCC: HTB-88 CVCL: CVCL_0628 disease: leiomyosarcoma CHEMBL: CHEMBL3308552 LCL-1286 ATCC: HTB-88,COSMIC ID:909720; ATCC HTB-88 SK-LU-1 cell ECACC: 93120835 ATCC: HTB-57 CVCL: CVCL_0629 LCL-1659 CHEMBL: CHEMBL3307447 SK-LU-1 SK-MEL-1 cell EFO: EFO_0002332 SK-MEL-1 CVCL: CVCL_0068 disease: malignant melanoma (skin primary) CHEMBL: CHEMBL3308365 LCL-1265 ATCC: HTB-67 SK-MEL-2 cell JX, YH disease: malignant melanoma (skin primary) ATCC: HTB-68 CHEMBL: CHEMBL3307743 LCL-1256 CVCL: CVCL_0069 WEB: http://www.atcc.org/products/all/HTB-68.aspx SK-MEL-2 EFO: EFO_0002079 SK-MEL-24 cell ATCC: HTB-71 disease: malignant melanoma SK-MEL-24 ATCC: COSMIC ID:909725; ATCC HTB-71,HTB-71 LCL-1281 CHEMBL: CHEMBL3308324 CVCL: CVCL_0599 SK-MEL-3 cell SK-MEL-3 LCL-1266 ATCC: HTB-69 disease: malignant melanoma (skin primary) SK-MEL-30 cell DSMZ: ACC 151 CVCL: CVCL_0039 HyperCLDB: cl4323 disease: melanoma SK-MEL-30 CHEMBL: CHEMBL3308128 LCL-1257 SK-MEL-5 cell SK-MEL-5 disease: malignant melanoma CHEMBL: CHEMBL3307744 EFO: EFO_0002080 LCL-1282 ATCC: HTB-70 Sanger: COSMIC ID:905956 CVCL: CVCL_0527 SK-MES cell HyperCLDB: cl4325 ATCC: HTB-58 LCL-1583 disease: carcinoma, squamous cell SK-MES SK-MM-2 cell HyperCLDB: cl5371 EFO: EFO_0005458 Sanger: COSMIC ID:753612 SK-MM-2 CVCL: CVCL_1699 LCL-2051 CHEMBL: CHEMBL3308277 SK-N-AS cell disease: embryonal neuro- blastoma (brain/neuroblast primary) SK-N-AS ATCC: CRL-2137 CVCL: CVCL_1700 EFO: EFO_0002859 LCL-1969 CHEMBL: CHEMBL3308785 SK-N-BE(2) cell SK-N-BE(2) ATCC: CRL-2271 disease: neuroblastoma brain primary) ECACC: 95011815 LCL-1980 SK-N-DZ cell SK-N-DZ CHEMBL: CHEMBL3308474 disease: embryonal neuro- blastoma (brain/neuroblast primary) LCL-1970 ATCC: CRL-2149 CVCL: CVCL_1701 EFO: EFO_0002336 SK-NEP-1 cell disease: Wilmstumor (kidney primary) ATCC: HTB-48 CVCL: CVCL_0631 EFO: EFO_0002337 CHEMBL: CHEMBL3308141 SK-NEP-1 LCL-1802 SK-N-FI cell CHEMBL: CHEMBL3308278 LCL-1981 SK-N-FI disease: embryonal neuro- blastoma (brain/neuroblast primary) ATCC: CRL-2142 CVCL: CVCL_1702 SK-N-SH cell ATCC: HTB-11 EFO: EFO_0003072 CHEMBL: CHEMBL3307745 LCL-1971 SK-N-SH disease: neuroblastoma (brain primary) CVCL: CVCL_0531 SK-OV-3 cell CVCL: CVCL_0532 EFO: EFO_0002340 disease: adenocarcinoma (ovary primary) ECACC: 91091004 CHEMBL: CHEMBL3307746 SK-OV-3 ATCC: HTB-77 LCL-1517 SK-PN-DW cell LCL-1048 CHEMBL: CHEMBL3308886 Sanger: COSMIC ID:909731 ATCC: CRL-2139 SK-PN-DW disease: retroperitoneal; malignant; primitive neuroectodermal tumor CVCL: CVCL_1703 SK-UT-1 cell Sanger: COSMIC ID:909732 SK-UT-1 LCL-1508 CVCL: CVCL_0533 CHEMBL: CHEMBL3308848 disease: mesodermal tumor (mixed); consistent with leiomyosarcoma ATCC: HTB-114 SNB-19 cell HyperCLDB: cl5372 DSMZ: ACC 325 ZN EFO: EFO_0002342 SNB-19 CVCL: CVCL_0535 LCL-1363 CHEMBL: CHEMBL3307552 SNU-1 cell LCL-1888 disease: gastric carcinoma SNU-1 CVCL: CVCL_0099 EFO: EFO_0002343 CHEMBL: CHEMBL3307455 ATCC: CRL-5971 SNU-16 cell CVCL: CVCL_0076 CHEMBL: CHEMBL3307273 EFO: EFO_0002344 ATCC: CRL-5974 LCL-1889 SNU-16 disease: gastric carcinoma (stomach primary) SNU-182 cell LCL-1932 ATCC: CRL-2235 SNU-182 disease: hepatocellular carcinoma SNU-387 cell EFO: EFO_0002346 ATCC: CRL-2237 CHEMBL: CHEMBL3308817 SNU-387 CVCL: CVCL_0250 disease: pleomorphic hepatocellular carcinoma LCL-1933 SNU-398 cell CVCL: CVCL_0077 disease: hepatocellular carcinoma EFO: EFO_0002347 LCL-1934 SNU-398 ATCC: CRL-2233 CHEMBL: CHEMBL3307619 SNU-423 cell disease: pleomorphic hepatocellular carcinoma LCL-1935 EFO: EFO_0002348 CVCL: CVCL_0366 ATCC: CRL-2238 CHEMBL: CHEMBL3308367 SNU-423 SNU-449 cell ATCC: CRL-2234 SNU-449 CHEMBL: CHEMBL3308480 LCL-1936 CVCL: CVCL_0454 disease: hepatocellular carcinoma EFO: EFO_0002349 SNU-475 cell CHEMBL: CHEMBL3308787 ATCC: CRL-2236 LCL-1937 CVCL: CVCL_0497 SNU-475 disease: hepatocellular carcinoma EFO: EFO_0002350 SNU-5 cell EFO: EFO_0002351 CVCL: CVCL_0078 LCL-1890 disease: gastric carcinoma (stomach primary) ATCC: CRL-5973 SNU-5 CHEMBL: CHEMBL3307458 SNU-C1 cell SNU-C1 CVCL: CVCL_1708 LCL-1194 Sanger: COSMIC ID:910905 disease: adenocarcinoma colon primary) ATCC: CRL-5972 CHEMBL: CHEMBL3308249 SNU-C2B cell SNU-C2B ATCC: CCL-250 disease: colorectal carcinoma LCL-1341 Sanger: COSMIC ID:909740 CVCL: CVCL_1710 CHEMBL: CHEMBL3308279 SR cell ATCC: CRL-2262 LCL-1129 SR CVCL: CVCL_1711 CHEMBL: CHEMBL3307586 disease: large cell immuno- blastic lymphoma (unknown primary) EFO: EFO_0002352 ST486 cell LCL-2026 disease: Burkitts lymphoma EFO: EFO_0002353 CVCL: CVCL_1712 ATCC: CRL-1647 CHEMBL: CHEMBL3308887 ST486 SU.86.86 cell disease: ductal carcinoma (pancreas primary) LCL-1747 SU.86.86 ATCC: CRL-1837 SU-DHL-1 cell LCL-1918 EFO: EFO_0005461 CVCL: CVCL_0538 CHEMBL: CHEMBL3308303 HyperCLDB: cl5376 DSMZ: ACC 356 SU-DHL-1 SUP-B15 cell an immortal human B cell line cell that is derived from a 8-year-old Caucasian male human patient with an acute lymphoblastic leukemia. disease: acute lymphoblastic leukemia CRL-1929 WEB: http://www.atcc.org/~/ps/CRL-1929.ashx LCL-1041 ATCC CRL-1929 WEB: http://www.atcc.org/products/all/CRL-1929.aspx ATCC: CRL-1929 SUP-B15 SUP-T1 cell LCL-1023 CVCL: CVCL_1714 SUP-T1 disease: acute T cell leukemia CHEMBL: CHEMBL3308368 ATCC: CRL-1942 SVG p12 cell LCL-2079 CRL-8621 SVG p12 disease: SV40 transformed ATCC: CRL-8621 SW 1088 cell CVCL: CVCL_1715 SW 1088 CHEMBL: CHEMBL3307573 ATCC: HTB-12 disease: astrocytoma LCL-1398 EFO: EFO_0002358 SW 1116 cell ECACC: 87071006 HyperCLDB: cl4429 LCL-1200 disease: adenocarcinoma, grade II SW 1116 SW 1271 cell disease: carcinoma; small cell lung cancer LCL-1824 ATCC: CRL-2177 SW 1271 SW 13 cell ZN LCL-1676 ECACC: 87031801 HyperCLDB: cl4435 SW 13 SW 1417 cell disease: adenocarcinoma, grade III HyperCLDB: cl4430 ECACC: 90102543 SW 1417 LCL-1185 SW 1463 cell HyperCLDB: cl4431 SW 1463 LCL-1291 ECACC: 90112713 SW 156 cell SW 156 ATCC: CRL-2175 disease: hypernephroma LCL-1758 SW 1573 cell disease: alveolar cell carcinoma CVCL: CVCL_1720 LCL-1799 CHEMBL: CHEMBL3307980 ATCC: CRL-2170 EFO: EFO_0002363 SW 1573 SW 1783 cell SW 1783 ATCC: HTB-13 CHEMBL: CHEMBL3308369 LCL-1399 EFO: EFO_0002364 CVCL: CVCL_1722 disease: astrocytoma SW 1990 cell disease: adenocarcinoma (pancreas primary) LCL-1750 ATCC: CRL-2172 SW 1990 SW 48 cell HyperCLDB: cl4438 EFO: EFO_0002365 CHEMBL: CHEMBL3308789 CVCL: CVCL_1723 ECACC: 89012702 LCL-1186 SW 48 SW 626 cell SW 626 LCL-1529 disease: adenocarcinoma (colon primary) ATCC: HTB-78 SW 780 cell disease: transitional cell carcinoma CHEMBL: CHEMBL3308468 CVCL: CVCL_1728 LCL-1718 SW 780 EFO: EFO_0002371 ATCC: CRL-2169 SW 900 cell ATCC: HTB-59 LCL-1593 disease: squamous cell carcinoma SW 900 CHEMBL: CHEMBL3308819 EFO: EFO_0002374 CVCL: CVCL_1731 SW-1710 cell CVCL: CVCL_1721 CHEMBL: CHEMBL3308804 HyperCLDB: cl5378 disease: carcinoma, transitional cell LCL-1719 DSMZ: ACC 426 SW-1710 SW403 cell disease: colorectal adenocarcinoma SW403 ATCC: CCL-230 LCL-1195 Sanger: COSMIC ID:910908 SW527 cell disease: Pagets disease ATCC: CRL-7940 SW527 LCL-1474 SW620 cell CVCL: CVCL_0547 disease: colorectal adenocarcinoma (colon primary) SW620 ATCC: CCL-227 LCL-1157 EFO: EFO_0002368 CHEMBL: CHEMBL3307944 SW756 cell LCL-1544 CHEMBL: CHEMBL3308790 CVCL: CVCL_1727 disease: squamous cell carcinoma ATCC: CRL-10302 EFO: EFO_0002370 SW756 SW837 cell CHEMBL: CHEMBL3308361 SW837 LCL-1292 CVCL: CVCL_1729 EFO: EFO_0002372 ATCC: CCL-235 SW-948 cell SW-948 LCL-1187 ATCC: CCL-237 HyperCLDB: cl5380 T24 cell T24 LCL-1709 ATCC: HTB-4 disease: transitional cell carcinoma HyperCLDB: cl5381 T84 cell ATCC: CCL-248 LCL-1166 T84 disease: colorectal carcinoma (colon primary) EFO: EFO_0002084 ECACC: 88021101 CHEMBL: CHEMBL3307275 CVCL: CVCL_0555 T98G cell T98G ATCC: CRL-1690 CHEMBL: CHEMBL3307777 disease: glioblastoma multiforme HyperCLDB: cl4478 LCL-1357 EFO: EFO_0002085 CVCL: CVCL_0556 TANOUE cell TANOUE HyperCLDB: cl5382 ACC 399 LCL-1095 disease: leukemia, B cell TCCSUP cell disease: transitional cell carcinoma HyperCLDB: cl5383 ATCC: HTB-5 LCL-1720 TCCSUP Tera-1 cell Tera-1 ATCC: HTB-105 LCL-1902 disease: embryonal malignant carcinoma TF-1 cell CHEMBL: CHEMBL3307972 LCL-1077 disease: model for cytokine (IL-3) signaling pathways and myeloid progenitor cell differentiation CRL-2003 ATCC: CRL-2003 CVCL: CVCL_0559 TF-1 TF-1.CN5a.1 cell CRL-2512 TF-1.CN5a.1 disease: erythroblast; erythroleukemia; CTNF responsive LCL-1078 ATCC: CRL-2512 TF-1a cell TF-1a LCL-1079 ATCC: CRL-2451 CRL-2451 disease: control cell line for TF-1 THP-1 cell LCL-1072 ATCC: TIB-202 EFO: EFO_0001253 disease: acute monocytic leukemia CVCL: CVCL_0006 HyperCLDB: cl4514 CHEMBL: CHEMBL3307574 THP-1 Toledo cell disease: diffuse large cell lymphoma, non-Hodgkins ATCC: CRL-2631 Toledo LCL-1124 TOV-112D cell disease: primary malignant adenocarcinoma; endometrioid carcinoma ATCC: CRL-11731 TOV-112D LCL-1920 TOV-21G cell LCL-1530 disease: primary malignant adenocarcinoma; clear cell carcinoma TOV-21G ATCC: CRL-11730 TT cell TT ATCC: COSMIC ID:930299; ATCC CRL-1803,CRL-1803 disease: medulla carcinoma CHEMBL: CHEMBL3308145 CVCL: CVCL_1774 EFO: EFO_0002382 LCL-1690 ATCC: CRL-1803 TUR cell LCL-2063 disease: histiocytic lymphoma; neomycin resistant ATCC: CRL-2367 TUR CHEMBL: CHEMBL3308519 CVCL: CVCL_1775 U-118 MG cell disease: glioblastoma; astrocytoma LCL-1358 U-118 MG ATCC: HTB-15 U-138 MG cell U-138 MG disease: glioblastoma LCL-1359 ATCC: HTB-16 U-2 OS cell LCL-1431 ATCC: HTB-96 CHEMBL: CHEMBL3307757 CVCL: CVCL_0042 U-2 OS EFO: EFO_0002869 U-251 MG cell LCL-1400 U-251 MG JHSF: IFO50288 HyperCLDB: cl4583 ZN U266B1 cell ATCC: TIB-196 ECACC: 85051003 disease: plasmacytoma; myeloma U266B1 LCL-2050 U373 MG cell U373 MG HyperCLDB: cl4589 ZN disease:glioblastoma LCL-1360 ECACC: 89081403 U-698-M cell LCL-1008 ACC 4 U-698-M HyperCLDB: cl4591 CHEMBL: CHEMBL3308280 disease: lymphoma, B cell CVCL: CVCL_0017 U-87 MG cell disease: glioblastoma; astrocytoma CVCL: CVCL_0022 LCL-1364 U-87 MG CHEMBL: CHEMBL3307575 ATCC: HTB-14 EFO: EFO_0001256 U-937 cell EFO: EFO_0001257 CHEMBL: CHEMBL3308006 ATCC: CRL-1593.2 CVCL: CVCL_0007 HyperCLDB: cl4605 U-937 LCL-1125 disease: histiocytic lymphoma MeSH: D020298 UACC-812 cell EFO: EFO_0001258 disease: ductal carcinoma ATCC: CRL-1897 CHEMBL: CHEMBL3308475 UACC-812 LCL-1319 CVCL: CVCL_1781 UACC-893 cell disease: primary ductal carcinoma CVCL: CVCL_1782 UACC-893 ATCC: CRL-1902 LCL-1320 EFO: EFO_0002385 CHEMBL: CHEMBL3308807 UMC-11 cell CVCL: CVCL_1784 UMC-11 disease: carcinoid ATCC: CRL-5975 LCL-1154 CHEMBL: CHEMBL3308343 EFO: EFO_0002386 UM-UC-3 cell CVCL: CVCL_1783 UM-UC-3 disease: transitional cell carcinoma CHEMBL: CHEMBL3307245 EFO: EFO_0002387 ATCC: CRL-1749 LCL-1721 VA-ES-BJ cell LCL-1945 ATCC: CRL-2138 CVCL: CVCL_1785 CHEMBL: CHEMBL3308888 disease: carcinoma, epithelioid (bone primary) VA-ES-BJ Sanger: COSMIC ID:688121 VM-CUB1 cell HyperCLDB: cl5393 VM-CUB1 DSMZ: ACC 400 disease: carcinoma, transitional cell LCL-1722 WiDr cell LCL-1169 WiDr ATCC: CCL-218 EFO: EFO_0002389 CHEMBL: CHEMBL3307674 disease: colorectal adenocarcinoma CVCL: CVCL_2760 ECACC: 85111501 WM 266-4 cell WM 266-4 HyperCLDB: cl4726 LCL-1259 ECACC: 91061233 disease: melanoma WM-115 cell ATCC: CRL-1675 EFO: EFO_0002390 LCL-1260 CVCL: CVCL_0040 WM-115 HyperCLDB: cl4727 CHEMBL: CHEMBL3308813 WM1552C cell disease: primary superficial spreading melanoma in radial growth phase/vertical growth phase WM1552C LCL-1261 ATCC: CRL-2808 WM278 cell disease: nodular melanoma in vertical growth phase WM278 ATCC: CRL-2809 LCL-1262 WM35 cell WM35 ATCC: CRL-2807 LCL-1263 disease: primary superficial spreading melanoma in radial growth phase/vertical growth phase WM793B cell WM793B ATCC: CRL-2806 disease: primary superficial spreading melanoma in vertical growth phase LCL-1264 WSU-NHL cell WSU-NHL HyperCLDB: cl4734 DSMZ: ACC 58 LCL-1955 CVCL: CVCL_1793 CHEMBL: CHEMBL3308281 YAPC cell CVCL: CVCL_1794 DSMZ: ACC 382 YAPC LCL-1792 HyperCLDB: cl5394 CHEMBL: CHEMBL3307253 YT cell CHEMBL: CHEMBL3308146 DSMZ: ACC 434 HyperCLDB: cl5395 LCL-1913 YT CVCL: CVCL_1797 ZR-75-1 cell disease: ductal carcinoma (mammary gland epithelium primary) CVCL: CVCL_0588 ZR-75-1 CHEMBL: CHEMBL3307615 EFO: EFO_0001262 LCL-1321 ATCC: CRL-1500 ZR-75-30 cell ATCC: CRL-1504 EFO: EFO_0001263 disease: ductal carcinoma (mammary gland epithelium primary) ZR-75-30 LCL-1322 CHEMBL: CHEMBL3308094 CVCL: CVCL_1661 immortal human pelvic fin-derived cell line cell An immortal pelvic fin-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human round window-derived cell line cell An immortal round window-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human bipolar neuron cell line cell An immortal bipolar neuron cell line cell that derives from human. Yue Liu, Yongqun He immortal human right ureter-derived cell line cell An immortal right ureter-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human myeloblast cell line cell An immortal myeloblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human mammary gland-derived cell line cell An immortal mammary gland-derived cell line cell that derives from human. Yongqun He TGW cell LCL-1962 TGW Oliver He, Jiangan Xie JHSF: JCRB0618 ETK-1 cell Sanger: COSMIC ID:906861 LCL-1789 Oliver He, Jiangan Xie ETK-1 AGR-ON cell ATCC: CRL-8199 Oliver He, Jiangan Xie LCL-1033 AGR-ON BCWM.1 cell BCWM.1 LCL-2094 DFCC - treon: Oliver He, Jiangan Xie DND-41 cell DSMZ: ACC 525 DND-41 LCL-1036 Oliver He, Jiangan Xie EJM cell Oliver He, Jiangan Xie EJM DSMZ: ACC 560 LCL-2042 J.gamma1 cell Oliver He, Jiangan Xie LCL-2038 ATCC: CRL-2678 J.gamma1 J.gamma1.WT cell J.gamma1.WT Oliver He, Jiangan Xie LCL-2039 ATCC: CRL-2679 JURL-MK1 cell JURL-MK1 LCL-1101 DSMZ: ACC 532 Oliver He, Jiangan Xie JURL-MK2 cell JURL-MK2 DSMZ: ACC 533 Oliver He, Jiangan Xie LCL-1102 K562/ADM cell JHSF: JCRB1002 LCL-1104 Oliver He, Jiangan Xie K562/ADM KCL-22 cell Oliver He, Jiangan Xie LCL-1105 DSMZ: ACC 519 KCL-22 KMS-12-BM cell LCL-2043 DSMZ: ACC 551 KMS-12-BM Oliver He, Jiangan Xie KMS-12-PE cell Oliver He, Jiangan Xie JHSF: JCRB0430 KMS-12-PE LCL-2044 KY821 cell JHSF: JCRB0105 LCL-1004 KY821 Oliver He, Jiangan Xie KY821A3 cell KY821A3 LCL-2040 Oliver He, Jiangan Xie JHSF: JCRB0105.1 LC4-1 cell Oliver He, Jiangan Xie JHSF: JCRB0114 LC4-1 LCL-1037 ME-1 cell LCL-1059 Oliver He, Jiangan Xie DSMZ: ACC 537 ME-1 MOLM-13 cell MOLM-13 DSMZ: ACC 554 LCL-1061 Oliver He, Jiangan Xie MOLP-8 cell DSMZ: ACC 569 MOLP-8 LCL-2047 Oliver He, Jiangan Xie NKM-1 cell Sanger: COSMIC ID:908448 NKM-1 Oliver He, Jiangan Xie LCL-1073 NOMO-1 cell NOMO-1 LCL-1074 Sanger: COSMIC ID:908451 Oliver He, Jiangan Xie NOMO-1/ADM cell NOMO-1/ADM Oliver He, Jiangan Xie JHSF: JCRB1069 LCL-1064 OCI-AML3 cell DSMZ: ACC 582 LCL-1066 Oliver He, Jiangan Xie OCI-AML3 OCI-M1 cell Oliver He, Jiangan Xie LCL-1068 DSMZ: ACC 529 OCI-M1 P31/FUJ cell P31/FUJ LCL-1069 JHSF: JCRB0091 Oliver He, Jiangan Xie PL-21 cell PL-21 DSMZ: ACC 536 LCL-1070 Oliver He, Jiangan Xie RPMI-8402 cell Oliver He, Jiangan Xie RPMI-8402 DSMZ: ACC 290 LCL-1022 RPMI-8866 cell LCL-1113 Oliver He, Jiangan Xie Sanger: COSMIC ID:910544 RPMI-8866 ES1 cell LCL-1439 Oliver He, Jiangan Xie Sanger: COSMIC ID:949158 ES1 ES3 cell Oliver He, Jiangan Xie LCL-1440 Sanger: COSMIC ID:684055 ES3 ES4 cell ES4 Sanger: COSMIC ID:949156 LCL-1441 Oliver He, Jiangan Xie ES5 cell ES5 Sanger: COSMIC ID:684057 LCL-1442 Oliver He, Jiangan Xie ES6 cell Sanger: COSMIC ID:949157 ES6 LCL-1443 Oliver He, Jiangan Xie ES7 cell Oliver He, Jiangan Xie ES7 Sanger: COSMIC ID:684059 LCL-1444 ES8 cell Oliver He, Jiangan Xie ES8 Sanger: COSMIC ID:949155 LCL-1445 EW-1 cell Oliver He, Jiangan Xie Sanger: COSMIC ID:949163 EW-1 LCL-1446 EW-11 cell LCL-1447 Oliver He, Jiangan Xie Sanger: COSMIC ID:684062 EW-11 EW-13 cell Oliver He, Jiangan Xie EW-13 Sanger: COSMIC ID:949166 LCL-1448 EW-16 cell Oliver He, Jiangan Xie EW-16 LCL-1449 Sanger: COSMIC ID:949165 EW-18 cell LCL-1450 Oliver He, Jiangan Xie Sanger: COSMIC ID:949164 EW-18 EW-24 cell EW-24 Oliver He, Jiangan Xie LCL-1451 Sanger: COSMIC ID:949168 EW-3 cell EW-3 Sanger: COSMIC ID:949161 Oliver He, Jiangan Xie LCL-1452 EW-7 cell Sanger: COSMIC ID:949160 Oliver He, Jiangan Xie LCL-1453 EW-7 G-292 Clone A141B1 cell LCL-1420 Oliver He, Jiangan Xie G-292 Clone A141B1 ECACC: 90110522 HuO9 cell HuO9 Oliver He, Jiangan Xie LCL-1423 JHSF: JCRB0427 HuO9N2 cell HuO9N2 JHSF: JCRB0428 LCL-1424 Oliver He, Jiangan Xie NY cell LCL-1429 NY JHSF: JCRB0614 Oliver He, Jiangan Xie RH-1 cell LCL-1456 Oliver He, Jiangan Xie RH-1 DSMZ: ACC 493 TC-71 cell TC-71 Oliver He, Jiangan Xie LCL-1438 DSMZ: ACC 516 AM-38 cell Sanger: COSMIC ID:910933 AM-38 Oliver He, Jiangan Xie LCL-1366 B2-17 cell Sanger: COSMIC ID:911904 LCL-1367 Oliver He, Jiangan Xie B2-17 Becker cell LCL-1368 Becker Oliver He, Jiangan Xie Sanger: COSMIC ID:906746 D-247MG cell LCL-1370 Sanger: COSMIC ID:946367 D-247MG Oliver He, Jiangan Xie D-263MG cell Sanger: COSMIC ID:946368 Oliver He, Jiangan Xie LCL-1371 D-263MG D-336MG cell Oliver He, Jiangan Xie LCL-1372 Sanger: COSMIC ID:946369 D-336MG D-392MG cell Oliver He, Jiangan Xie Sanger: COSMIC ID:946370 LCL-1373 D-392MG D-423MG cell D-423MG LCL-1374 Sanger: COSMIC ID:946372 Oliver He, Jiangan Xie D-502MG cell Oliver He, Jiangan Xie LCL-1375 D-502MG Sanger: COSMIC ID:946373 D-542MG cell LCL-1376 Oliver He, Jiangan Xie D-542MG Sanger: COSMIC ID:753549 D-566MG cell Sanger: COSMIC ID:946377 D-566MG Oliver He, Jiangan Xie LCL-1377 GB-1 cell LCL-1378 Oliver He, Jiangan Xie Sanger: COSMIC ID:687568 GB-1 KALS-1 cell Oliver He, Jiangan Xie Sanger: COSMIC ID:907271 LCL-1380 KALS-1 KINGS-1 cell KINGS-1 LCL-1381 Oliver He, Jiangan Xie Sanger: COSMIC ID:907279 KNS-42 cell LCL-1382 Sanger: COSMIC ID:907282 KNS-42 Oliver He, Jiangan Xie KNS-81-FD cell Sanger: COSMIC ID:924188 LCL-1383 KNS-81-FD Oliver He, Jiangan Xie KS-1 cell Oliver He, Jiangan Xie KS-1 Sanger: COSMIC ID:907313 LCL-1384 NMC-G1 cell LCL-1385 Oliver He, Jiangan Xie Sanger: COSMIC ID:908449 NMC-G1 no-10 cell Sanger: COSMIC ID:908452 Oliver He, Jiangan Xie no-10 LCL-1386 no-11 cell no-11 Sanger: COSMIC ID:908450 Oliver He, Jiangan Xie LCL-1387 ONS-76 cell ONS-76 Oliver He, Jiangan Xie Sanger: COSMIC ID:909248 LCL-1578 SF126 cell SF126 Oliver He, Jiangan Xie LCL-1388 Sanger: COSMIC ID:909712 SF268 cell Sanger: COSMIC ID:905986 SF268 Oliver He, Jiangan Xie LCL-1389 SF539 cell Oliver He, Jiangan Xie SF539 Sanger: COSMIC ID:905984 LCL-1390 SK-MG-1 cell Sanger: COSMIC ID:909729 LCL-1391 SK-MG-1 Oliver He, Jiangan Xie SNB75 cell LCL-1346 Sanger: COSMIC ID:905982 Oliver He, Jiangan Xie SNB75 YH-13 cell YH-13 Oliver He, Jiangan Xie Sanger: COSMIC ID:909905 LCL-1392 YKG-1 cell Oliver He, Jiangan Xie JHSF: JCRB0746 YKG-1 LCL-1361 600MPE cell LCL-2073 600MPE Oliver He, Jiangan Xie HCC2185 cell HCC2185 LCL-2074 Oliver He, Jiangan Xie HCC3153 cell LCL-2075 Oliver He, Jiangan Xie HCC3153 HDQ-P1 cell DSMZ: ACC 494 LCL-1481 Oliver He, Jiangan Xie HDQ-P1 JIMT-1 cell DSMZ: ACC 589 Oliver He, Jiangan Xie JIMT-1 LCL-1482 LY2 cell LY2 Oliver He, Jiangan Xie LCL-2076 MRK-nu-1 cell JHSF: JCRB0628 MRK-nu-1 LCL-1487 Oliver He, Jiangan Xie MX-1 cell LCL-2072 MX-1 Oliver He, Jiangan Xie SUM1315MO2 cell SUM1315MO2 Oliver He, Jiangan Xie LCL-2066 SUM149PT cell LCL-2067 Oliver He, Jiangan Xie SUM149PT SUM159PT cell LCL-2068 Oliver He, Jiangan Xie SUM159PT SUM185PE cell SUM185PE Oliver He, Jiangan Xie LCL-2069 SUM225CWN cell SUM225CWN LCL-2070 Oliver He, Jiangan Xie SUM229PE cell LCL-2065 Oliver He, Jiangan Xie SUM229PE T47D cell LCL-1486 T47D ECACC: 85102201 Oliver He, Jiangan Xie YMB-1 cell LCL-1488 YMB-1 JHSF: JCRB0823 Oliver He, Jiangan Xie ZR75B cell ZR75B Oliver He, Jiangan Xie LCL-2077 BOKU cell LCL-1545 Oliver He, Jiangan Xie BOKU Sanger: COSMIC ID:753536 HeLa ICRP cell Oliver He, Jiangan Xie HeLa ICRP LCL-2096 HeLa ICRP Bcl-2-mCherry cell LCL-2097 HeLa ICRP Bcl-2-mCherry Oliver He, Jiangan Xie HeLa ICRP Bcl-XL-mCherry cell HeLa ICRP Bcl-XL-mCherry Oliver He, Jiangan Xie LCL-2098 HeLa ICRP FLIP-L-mCherry cell HeLa ICRP FLIP-L-mCherry Oliver He, Jiangan Xie LCL-2099 HeLa ICRP FLIP-S-mCherry cell Oliver He, Jiangan Xie LCL-2100 HeLa ICRP FLIP-S-mCherry SKG-IIIb cell SKG-IIIb JHSF: JCRB0232.1 Oliver He, Jiangan Xie LCL-1543 HCE-4 cell Sanger: COSMIC ID:753559 HCE-4 Oliver He, Jiangan Xie LCL-1563 KYSE-220 cell Oliver He, Jiangan Xie JHSF: JCRB1086 KYSE-220 LCL-1559 KYSE-50 cell KYSE-50 Oliver He, Jiangan Xie LCL-1560 JHSF: JCRB0189 T.T cell LCL-1561 Oliver He, Jiangan Xie T.T JHSF: JCRB0262 T.Tn cell JHSF: JCRB0261 T.Tn LCL-1562 Oliver He, Jiangan Xie TE-12 cell LCL-1567 TE-12 Oliver He, Jiangan Xie Sanger: COSMIC ID:946356 OCUG-1 cell JHSF: JCRB0191 OCUG-1 LCL-1800 Oliver He, Jiangan Xie BB30-HNC cell BB30-HNC LCL-1573 Oliver He, Jiangan Xie Sanger: COSMIC ID:753531 BB49-HNC cell LCL-1574 Sanger: COSMIC ID:753532 BB49-HNC Oliver He, Jiangan Xie BICR 10 cell Oliver He, Jiangan Xie LCL-1203 ECACC: 4072103 BICR 10 BICR 22 cell BICR 22 Oliver He, Jiangan Xie ECACC: 4072106 LCL-1213 BICR 31 cell ECACC: 4072107 Oliver He, Jiangan Xie BICR 31 LCL-1214 BICR 78 cell Oliver He, Jiangan Xie LCL-1205 BICR 78 ECACC: 4072111 HO-1-N-1 cell LCL-1204 JHSF: JCRB0831 HO-1-N-1 Oliver He, Jiangan Xie KON cell JHSF: JCRB0194 Oliver He, Jiangan Xie KON LCL-1207 KOSC-2 cl3-43 cell LCL-1227 JHSF: JCRB0126.1 Oliver He, Jiangan Xie KOSC-2 cl3-43 LB771-HNC cell LB771-HNC Oliver He, Jiangan Xie LCL-1575 Sanger: COSMIC ID:753583 OSC-19 cell LCL-1219 OSC-19 Oliver He, Jiangan Xie JHSF: JCRB0198 OSC-20 cell JHSF: JCRB0197 Oliver He, Jiangan Xie OSC-20 LCL-1220 PE/CA-PJ15 cell ECACC: 96121230 Oliver He, Jiangan Xie LCL-1212 PE/CA-PJ15 SAT cell JHSF: JCRB1027 LCL-1210 SAT Oliver He, Jiangan Xie SKN-3 cell SKN-3 JHSF: JCRB1039 LCL-1211 Oliver He, Jiangan Xie C170 cell C170 ECACC: 97071507 LCL-1156 Oliver He, Jiangan Xie CaR-1 cell CaR-1 Oliver He, Jiangan Xie JHSF: JCRB0207 LCL-1288 CCK-81 cell LCL-1171 CCK-81 Oliver He, Jiangan Xie JHSF: JCRB0208 CL-11 cell CL-11 LCL-1167 Oliver He, Jiangan Xie DSMZ: ACC 467 CL-40 cell LCL-1199 DSMZ: ACC 535 CL-40 Oliver He, Jiangan Xie CoCM-1 cell LCL-1196 CoCM-1 Oliver He, Jiangan Xie JHSF: JCRB0257 COLO-320-HSR cell LCL-1189 COLO-320-HSR Oliver He, Jiangan Xie Sanger: COSMIC ID:910569 Gp2D cell ECACC: 95090714; COSMIC ID:907292,95090714 Oliver He, Jiangan Xie Gp2D LCL-1188 HCC2998 cell Sanger: COSMIC ID:905971 LCL-1191 Oliver He, Jiangan Xie HCC2998 HCC-56 cell Oliver He, Jiangan Xie JHSF: JCRB1037 LCL-1177 HCC-56 HUTU-80 cell HUTU-80 Oliver He, Jiangan Xie LCL-1150 Sanger: COSMIC ID:907073 KM12 cell Oliver He, Jiangan Xie Sanger: COSMIC ID:905989 LCL-1192 KM12 LS-1034 cell LS-1034 Oliver He, Jiangan Xie LCL-1336 Sanger: COSMIC ID:917486 LS-123 cell LS-123 LCL-1193 Oliver He, Jiangan Xie Sanger: COSMIC ID:907792 LS-411N cell Oliver He, Jiangan Xie Sanger: COSMIC ID:907794 LS-411N LCL-1337 LS-513 cell Sanger: COSMIC ID:907795 Oliver He, Jiangan Xie LCL-1338 LS-513 MDST8 cell ECACC: 99011801 Oliver He, Jiangan Xie LCL-1164 MDST8 OUMS-23 cell OUMS-23 LCL-1165 JHSF: JCRB1022 Oliver He, Jiangan Xie RCM-1 cell Oliver He, Jiangan Xie RCM-1 LCL-1290 JHSF: JCRB0256 621-101 cell Oliver He, Jiangan Xie 621-101 LCL-2004 BWH: 621-101,not available A498 cell Oliver He, Jiangan Xie Sanger: COSMIC ID:905948 A498 LCL-1761 BB65-RCC cell LCL-1763 BB65-RCC Sanger: COSMIC ID:753533 Oliver He, Jiangan Xie HA7-RCC cell Oliver He, Jiangan Xie LCL-1764 HA7-RCC Sanger: COSMIC ID:753558 KMRC-1 cell Oliver He, Jiangan Xie JHSF: JCRB1010 KMRC-1 LCL-1775 KMRC-20 cell LCL-1755 JHSF: JCRB1071 Oliver He, Jiangan Xie KMRC-20 LB1047-RCC cell Sanger: COSMIC ID:753577 LB1047-RCC Oliver He, Jiangan Xie LCL-1765 LB2241-RCC cell LCL-1766 Oliver He, Jiangan Xie LB2241-RCC Sanger: COSMIC ID:753578 LB996-RCC cell LB996-RCC Oliver He, Jiangan Xie LCL-1767 Sanger: COSMIC ID:753585 RXF393 cell LCL-1770 RXF393 Sanger: COSMIC ID:905978 Oliver He, Jiangan Xie TK10 cell Sanger: COSMIC ID:905980 LCL-1771 TK10 Oliver He, Jiangan Xie VMRC-RCZ cell VMRC-RCZ LCL-1760 Oliver He, Jiangan Xie JHSF: JCRB0827 FOCUS cell LCL-2078 Oliver He, Jiangan Xie FOCUS HLE cell LCL-1939 HLE Oliver He, Jiangan Xie JHSF: JCRB0404 HLF cell LCL-1938 Oliver He, Jiangan Xie HLF JHSF: JCRB0405 huH-1 cell huH-1 LCL-1940 Oliver He, Jiangan Xie JHSF: JCRB0199 Huh7 cell JHSF: JCRB0403 Oliver He, Jiangan Xie Huh7 LCL-1926 JHH-1 cell Oliver He, Jiangan Xie LCL-1928 JHSF: JCRB1062 JHH-1 JHH-2 cell Oliver He, Jiangan Xie JHH-2 JHSF: JCRB1028 LCL-1929 JHH-4 cell JHH-4 Oliver He, Jiangan Xie JHSF: JCRB0435 LCL-1930 JHH-6 cell JHH-6 Oliver He, Jiangan Xie LCL-1923 JHSF: JCRB1030 JHH-7 cell LCL-1931 JHH-7 Oliver He, Jiangan Xie JHSF: JCRB1031 COLO-668 cell Sanger: COSMIC ID:910692 LCL-1867 Oliver He, Jiangan Xie COLO-668 COR-L 105 cell ECACC: 92031918 Oliver He, Jiangan Xie COR-L 105 LCL-1635 EKVX cell Oliver He, Jiangan Xie LCL-2054 EKVX Sanger: COSMIC ID:905970 HARA cell Oliver He, Jiangan Xie LCL-1585 JHSF: JCRB1080.0 HARA HCC-15 cell DSMZ: ACC 496 HCC-15 Oliver He, Jiangan Xie LCL-1604 HCC-33 cell DSMZ: ACC 487 HCC-33 LCL-1833 Oliver He, Jiangan Xie HCC-366 cell HCC-366 DSMZ: ACC 492 Oliver He, Jiangan Xie LCL-1605 HCC-44 cell DSMZ: ACC 534 Oliver He, Jiangan Xie LCL-1606 HCC-44 HCC515 cell HCC515 Broad Institute: contact provider Oliver He, Jiangan Xie LCL-2084 HCC-78 cell Oliver He, Jiangan Xie DSMZ: ACC 563 LCL-1607 HCC-78 HCC-827 cell DSMZ: ACC 566 Oliver He, Jiangan Xie LCL-1608 HCC-827 HOP-62 cell Sanger: COSMIC ID:905972 LCL-1666 Oliver He, Jiangan Xie HOP-62 KHM-3S cell Oliver He, Jiangan Xie KHM-3S LCL-1876 JHSF: JCRB0138 LB647-SCLC cell Sanger: COSMIC ID:753582 LCL-1870 Oliver He, Jiangan Xie LB647-SCLC LC-1 sq cell JHSF: JCRB0258 Oliver He, Jiangan Xie LCL-1586 LC-1 sq LC-2-ad cell Sanger: COSMIC ID:907786 LC-2-ad Oliver He, Jiangan Xie LCL-1667 LU-134-A cell Sanger: COSMIC ID:753588 LU-134-A Oliver He, Jiangan Xie LCL-1871 Lu-134-A-H cell Oliver He, Jiangan Xie JHSF: JCRB0235 Lu-134-A-H LCL-1877 LU-139 cell LU-139 LCL-1872 Oliver He, Jiangan Xie Sanger: COSMIC ID:713878 LU-165 cell Oliver He, Jiangan Xie LU-165 Sanger: COSMIC ID:753589 LCL-1873 LU65A cell JHSF: JCRB0054 LCL-1905 Oliver He, Jiangan Xie LU65A LU65B cell LCL-1906 LU65B Oliver He, Jiangan Xie JHSF: JCRB0055 LU65C cell JHSF: JCRB0056 LCL-1907 LU65C Oliver He, Jiangan Xie LU99A cell LU99A LCL-1908 JHSF: JCRB0044 Oliver He, Jiangan Xie LU99B cell LCL-1909 Oliver He, Jiangan Xie JHSF: JCRB0057 LU99B LU99C cell JHSF: JCRB0058 Oliver He, Jiangan Xie LU99C LCL-1910 MS-1-L cell LCL-1835 MS-1-L JHSF: JCRB1081 Oliver He, Jiangan Xie NCI-H157 cell NCI-H157 LCL-1596 Sanger: COSMIC ID:911847 Oliver He, Jiangan Xie NCI-H3122 cell Oliver He, Jiangan Xie DFCI: n/a-1 LCL-1675 NCI-H3122 NCI-H322M cell NCI-H322M Oliver He, Jiangan Xie LCL-1674 Sanger: COSMIC ID:905967 NCI-H64 cell Sanger: COSMIC ID:688026 LCL-1874 NCI-H64 Oliver He, Jiangan Xie PC-3 [JPC-3] cell PC-3 [JPC-3] JHSF: JCRB0077 Oliver He, Jiangan Xie LCL-1664 RERF-LC-Ad1 cell JHSF: JCRB1020 Oliver He, Jiangan Xie LCL-1657 RERF-LC-Ad1 RERF-LC-MA cell LCL-1820 Oliver He, Jiangan Xie JHSF: JCRB0812 RERF-LC-MA RERF-LC-MS cell LCL-1665 Oliver He, Jiangan Xie RERF-LC-MS JHSF: JCRB0081 RERF-LC-Sq1 cell RERF-LC-Sq1 LCL-1592 Oliver He, Jiangan Xie JHSF: JCRB1019 SBC-1 cell Oliver He, Jiangan Xie SBC-1 LCL-1865 JHSF: JCRB0816 SBC-3 cell LCL-1879 SBC-3 JHSF: JCRB0818 Oliver He, Jiangan Xie SBC-5 cell JHSF: JCRB0819 Oliver He, Jiangan Xie SBC-5 LCL-1821 STC 1 cell JHSF: JCRB1053 LCL-1878 Oliver He, Jiangan Xie STC 1 VMRC-LCP cell Oliver He, Jiangan Xie VMRC-LCP LCL-1594 JHSF: JCRB0103 A3/KAW cell A3/KAW LCL-1149 JHSF: JCRB0101 Oliver He, Jiangan Xie AMO-1 cell DSMZ: ACC 538 AMO-1 Oliver He, Jiangan Xie LCL-1539 CI-1 cell Oliver He, Jiangan Xie LCL-1130 DSMZ: ACC 570 CI-1 DERL-2 cell LCL-1116 DERL-2 DSMZ: ACC 531 Oliver He, Jiangan Xie DOHH-2 cell DOHH-2 Sanger: COSMIC ID:906842 LCL-1143 Oliver He, Jiangan Xie NU-DUL-1 cell DSMZ: ACC 579 NU-DUL-1 Oliver He, Jiangan Xie LCL-1132 OCI-LY-19 cell OCI-LY-19 Oliver He, Jiangan Xie LCL-1121 DSMZ: ACC 528 P32/ISH cell LCL-2023 P32/ISH JHSF: JCRB0095 Oliver He, Jiangan Xie Ramos-2G6-4C10 cell ATCC: COSMIC ID:910401; ATCC CRL-1923,CRL-1923 Oliver He, Jiangan Xie Ramos-2G6-4C10 LCL-2027 RC-K8 cell RC-K8 Oliver He, Jiangan Xie DSMZ: ACC 561 LCL-1950 REC-1 cell DSMZ: ACC 584 Oliver He, Jiangan Xie REC-1 LCL-1123 SCC-3 cell LCL-1128 SCC-3 Oliver He, Jiangan Xie JHSF: JCRB0115 Sci-1 cell Sci-1 ECACC: 96090513 Oliver He, Jiangan Xie LCL-1951 SU-DHL-10 cell DSMZ: ACC 576 Oliver He, Jiangan Xie LCL-1134 SU-DHL-10 SU-DHL-16 cell Oliver He, Jiangan Xie LCL-1135 DSMZ: ACC 577 SU-DHL-16 SU-DHL-4 cell Oliver He, Jiangan Xie SU-DHL-4 DSMZ: ACC 495 LCL-1136 SU-DHL-5 cell DSMZ: ACC 571 LCL-1137 SU-DHL-5 Oliver He, Jiangan Xie SU-DHL-6 cell DSMZ: ACC 572 LCL-1138 Oliver He, Jiangan Xie SU-DHL-6 SU-DHL-8 cell DSMZ: ACC 573 SU-DHL-8 Oliver He, Jiangan Xie LCL-1139 SUP-M2 cell LCL-1919 SUP-M2 Oliver He, Jiangan Xie DSMZ: ACC 509 TK cell JHSF: JCRB0157 TK Oliver He, Jiangan Xie LCL-1953 VAL cell DSMZ: ACC 586 VAL LCL-1915 Oliver He, Jiangan Xie WSU-DLCL2 cell WSU-DLCL2 Oliver He, Jiangan Xie LCL-1954 DSMZ: ACC 575 SCCH-196 cell LCL-1403 SCCH-196 JHSF: JCRB0108 Oliver He, Jiangan Xie SW684 cell Sanger: COSMIC ID:909754 Oliver He, Jiangan Xie LCL-1490 SW684 SW872 cell Sanger: COSMIC ID:909756 SW872 Oliver He, Jiangan Xie LCL-1459 SW982 cell LCL-1880 Oliver He, Jiangan Xie ATCC: HTB-93,COSMIC ID:909759; ATCC HTB-93 SW982 KYM-1 cell JHSF: JCRB0627 Oliver He, Jiangan Xie KYM-1 LCL-1412 RH-30 cell RH-30 Oliver He, Jiangan Xie LCL-1414 DSMZ: ACC 489 RH-41 cell Oliver He, Jiangan Xie RH-41 DSMZ: ACC 592 LCL-1415 SJCRH30 cell LCL-1408 SJCRH30 ATCC: CRL-2061 Oliver He, Jiangan Xie TE-441-T cell Oliver He, Jiangan Xie TE-441-T ATCC: CRL-7767,COSMIC ID:924248; ATCC CRL-7767 LCL-1413 GOTO cell LCL-1974 Oliver He, Jiangan Xie GOTO JHSF: JCRB0612 KP-N-YN cell Oliver He, Jiangan Xie LCL-1985 JCRB: COSMIC ID:907314; JCRB IFO50431,IFO50431 KP-N-YN KP-N-YS cell KP-N-YS Oliver He, Jiangan Xie LCL-1986 Sanger: COSMIC ID:946363 LAN-6 cell LCL-1988 LAN-6 Oliver He, Jiangan Xie Sanger: COSMIC ID:949170 NB(TU)1-10 cell JHSF: JCRB0154 Oliver He, Jiangan Xie LCL-1976 NB(TU)1-10 NB10 cell NB10 Oliver He, Jiangan Xie Sanger: COSMIC ID:949171 LCL-1989 NB12 cell LCL-1990 NB12 Sanger: COSMIC ID:949172 Oliver He, Jiangan Xie NB13 cell NB13 Oliver He, Jiangan Xie LCL-1991 Sanger: COSMIC ID:949177 NB14 cell NB14 Oliver He, Jiangan Xie LCL-1992 Sanger: COSMIC ID:949178 NB17 cell LCL-1994 Oliver He, Jiangan Xie NB17 Sanger: COSMIC ID:949175 NB5 cell Sanger: COSMIC ID:949176 NB5 Oliver He, Jiangan Xie LCL-1995 NB6 cell LCL-1996 Sanger: COSMIC ID:949173 NB6 Oliver He, Jiangan Xie NB7 cell Sanger: COSMIC ID:949174 Oliver He, Jiangan Xie NB7 LCL-1997 NGP cell NGP Oliver He, Jiangan Xie LCL-2103 TASK1 cell Oliver He, Jiangan Xie LCL-1114 TASK1 JHSF: JCRB0139 KURAMOCHI cell Sanger: COSMIC ID:909975 LCL-1701 Oliver He, Jiangan Xie KURAMOCHI MCAS cell JHSF: JCRB0240 Oliver He, Jiangan Xie LCL-1493 MCAS OC-314 cell Oliver He, Jiangan Xie Sanger: COSMIC ID:909257 LCL-1516 OC-314 OVCAR-4 cell LCL-1697 Sanger: COSMIC ID:905990 Oliver He, Jiangan Xie OVCAR-4 OVISE cell OVISE Oliver He, Jiangan Xie JHSF: JCRB1043 LCL-1524 OVKATE cell LCL-1525 Oliver He, Jiangan Xie JHSF: JCRB1044 OVKATE OVMIU cell Oliver He, Jiangan Xie LCL-1526 OVMIU JHSF: JCRB1049 OVSAYO cell LCL-1527 JHSF: JCRB1047 Oliver He, Jiangan Xie OVSAYO OVTOKO cell OVTOKO LCL-1528 JHSF: JCRB1048 Oliver He, Jiangan Xie RKN cell JHSF: JCRB0176 LCL-1803 Oliver He, Jiangan Xie RKN RMG-I cell Oliver He, Jiangan Xie JHSF: JCRB0172 RMG-I LCL-1805 TYK-nu cell LCL-1700 JHSF: JCRB0234.0 Oliver He, Jiangan Xie TYK-nu KP-1N cell Oliver He, Jiangan Xie LCL-1793 JHSF: JCRB0177.0 KP-1N KP-1NL cell JHSF: JCRB0177.1 LCL-1794 KP-1NL Oliver He, Jiangan Xie KP-2 cell Oliver He, Jiangan Xie LCL-1728 JHSF: JCRB0181 KP-2 KP-3 cell Oliver He, Jiangan Xie KP-3 JHSF: JCRB0178.0 LCL-1723 KP-3L cell LCL-1724 Oliver He, Jiangan Xie JHSF: JCRB0178.1 KP-3L KP-4 cell KP-4 JHSF: JCRB0182 LCL-1725 Oliver He, Jiangan Xie MZ1-PC cell MZ1-PC Oliver He, Jiangan Xie Sanger: COSMIC ID:753595 LCL-1795 PL4 cell Oliver He, Jiangan Xie PL4 MGH: MGH-1134 LCL-1098 QGP-1 cell Oliver He, Jiangan Xie LCL-1754 JHSF: JCRB0183 QGP-1 SUIT-2 cell LCL-1729 SUIT-2 JHSF: JCRB1094 Oliver He, Jiangan Xie MPP-89 cell Oliver He, Jiangan Xie MPP-89 LCL-1229 Sanger: COSMIC ID:908150 LNCaP cell ATCC: CRL-1740 Oliver He, Jiangan Xie LNCaP LCL-1298 VCaP cell ATCC: CRL-2876 LCL-1147 Oliver He, Jiangan Xie VCaP A373-C6 cell ECACC: 97011321 A373-C6 LCL-1284 Oliver He, Jiangan Xie A4-Fuk cell Sanger: COSMIC ID:910934 LCL-1268 A4-Fuk Oliver He, Jiangan Xie COLO-679 cell Oliver He, Jiangan Xie COLO-679 DSMZ: ACC 264 LCL-1232 COLO-800 cell COLO-800 DSMZ: ACC 193 LCL-1233 Oliver He, Jiangan Xie COLO-818 cell DSMZ: ACC 81 Oliver He, Jiangan Xie COLO-818 LCL-1244 COLO-829 cell Sanger: COSMIC ID:687448 COLO-829 LCL-1269 Oliver He, Jiangan Xie CP50-MEL-B cell LCL-1270 CP50-MEL-B Oliver He, Jiangan Xie Sanger: COSMIC ID:753545 CP66-MEL cell CP66-MEL Oliver He, Jiangan Xie LCL-1271 Sanger: COSMIC ID:753546 GAK cell GAK Sanger: COSMIC ID:910932 Oliver He, Jiangan Xie LCL-1272 K2 cell K2 LCL-2091 Oliver He, Jiangan Xie LB2518-MEL cell Oliver He, Jiangan Xie Sanger: COSMIC ID:753579 LCL-1274 LB2518-MEL LB373-MEL-D cell LCL-1275 Oliver He, Jiangan Xie LB373-MEL-D Sanger: COSMIC ID:753581 LOXIMVI cell Sanger: COSMIC ID:905974 LOXIMVI Oliver He, Jiangan Xie LCL-1276 MMAC-SF cell MMAC-SF LCL-1277 RIKEN: COSMIC ID:925339; Riken RCB1200,RCB1200 Oliver He, Jiangan Xie MZ2-MEL cell Sanger: COSMIC ID:971777 Oliver He, Jiangan Xie MZ2-MEL LCL-1278 MZ7-mel cell Oliver He, Jiangan Xie Sanger: COSMIC ID:753596 MZ7-mel LCL-1279 SKMEL28 cell Oliver He, Jiangan Xie LCL-2092 SKMEL28 UACC-257 cell Sanger: COSMIC ID:905977 Oliver He, Jiangan Xie LCL-1283 UACC-257 VMRC-MELG cell VMRC-MELG LCL-1258 JHSF: JCRB0074 Oliver He, Jiangan Xie AZ-521 cell Oliver He, Jiangan Xie AZ-521 JHSF: JCRB0061 LCL-1533 FU97 cell LCL-1894 JHSF: JCRB1074 FU97 Oliver He, Jiangan Xie GT3TKB cell GT3TKB Oliver He, Jiangan Xie LCL-1895 Sanger: COSMIC ID:907041 IM-95 cell IM-95 JHSF: JCRB1075.0 Oliver He, Jiangan Xie LCL-1884 IM-95m cell JHSF: JCRB1075.1 Oliver He, Jiangan Xie LCL-1534 IM-95m MKN28 cell MKN28 LCL-1922 JHSF: JCRB0253 Oliver He, Jiangan Xie NUGC-2 cell LCL-1899 Oliver He, Jiangan Xie NUGC-2 JHSF: JCRB0821 NUGC-3 cell Oliver He, Jiangan Xie NUGC-3 JHSF: JCRB0822 LCL-1887 OCUM-1 cell OCUM-1 Oliver He, Jiangan Xie JHSF: JCRB0192 LCL-2002 RERF-GC-1B cell LCL-1537 RERF-GC-1B JHSF: JCRB1009 Oliver He, Jiangan Xie RF-48 cell LCL-1896 Sanger: COSMIC ID:909697 Oliver He, Jiangan Xie RF-48 SCH cell SCH Oliver He, Jiangan Xie LCL-1148 JHSF: JCRB0251 NCC-IT-A3 cell LCL-1903 JHSF: JCRB1005 Oliver He, Jiangan Xie NCC-IT-A3 NTERA-S-cl-D1 cell Sanger: COSMIC ID:908454 Oliver He, Jiangan Xie LCL-1901 NTERA-S-cl-D1 ASH-3 cell JHSF: JCRB1073 Oliver He, Jiangan Xie ASH-3 LCL-1682 HTC-C3 cell Oliver He, Jiangan Xie DSMZ: ACC 580 HTC-C3 LCL-1689 IHH-4 cell LCL-1693 IHH-4 JHSF: JCRB1079 Oliver He, Jiangan Xie K5 cell K5 Oliver He, Jiangan Xie LCL-1692 Sanger: COSMIC ID:924238 KMH-2 cell KMH-2 LCL-1684 JHSF: JCRB1066 Oliver He, Jiangan Xie TT2609-C02 cell LCL-1681 TT2609-C02 Oliver He, Jiangan Xie DSMZ: ACC 510 CAL-29 cell DSMZ: ACC 515 CAL-29 LCL-1711 Oliver He, Jiangan Xie DSH1 cell Sanger: COSMIC ID:753552 LCL-1706 DSH1 Oliver He, Jiangan Xie LB831-BLC cell Sanger: COSMIC ID:753584 LB831-BLC LCL-1707 Oliver He, Jiangan Xie AN3CA cell ATCC: HTB-111 LCL-1499 AN3CA Oliver He, Jiangan Xie EN cell DSMZ: ACC 564 EN Oliver He, Jiangan Xie LCL-1495 HEC-1 cell HEC-1 JHSF: JCRB0042 Oliver He, Jiangan Xie LCL-1496 Ishikawa cell Ishikawa LCL-1497 ECACC: 99040201 Oliver He, Jiangan Xie MES-SA/Dx-5 cell LCL-1510 Oliver He, Jiangan Xie MES-SA/Dx-5 ECACC: 95051031 SNG-M cell SNG-M Oliver He, Jiangan Xie LCL-1503 JHSF: JCRB0179 SW954 cell Oliver He, Jiangan Xie ATCC: COSMIC ID:924247; ATCC HTB-117,HTB-117 LCL-1295 SW954 SW962 cell SW962 Oliver He, Jiangan Xie LCL-1152 ATCC: COSMIC ID:909758; ATCC HTB-118,HTB-118 ALL-SIL cell Oliver He, Jiangan Xie DSMZ: ACC 511 ALL-SIL LCL-2059 HA1E cell Oliver He, Jiangan Xie LCL-2090 HA1E BROAD: HL60(S) cell JCRB: JCRB0163 HL60(S) LCL-1082 Oliver He, Jiangan Xie HL60RG cell HL60RG Oliver He, Jiangan Xie JCRB: JCRB0006 LCL-2056 HME1 cell ATCC: CRL-4010 HME1 LCL-2083 Oliver He, Jiangan Xie JJN-3 cell DSMZ: ACC 541 JJN-3 Oliver He, Jiangan Xie LCL-2052 JKT-beta-del cell LCL-2060 JCRB: JCRB0147 JKT-beta-del Oliver He, Jiangan Xie KARPAS-231 cell Oliver He, Jiangan Xie KARPAS-231 DSMZ: ACC 562 LCL-1087 KARPAS-620 cell LCL-2053 Oliver He, Jiangan Xie DSMZ: ACC 514 KARPAS-620 KO52 cell JCRB: JCRB0123 Oliver He, Jiangan Xie KO52 LCL-1080 KOPN-8 cell KOPN-8 LCL-1088 DSMZ: ACC 552 Oliver He, Jiangan Xie L-1236 cell LCL-2010 DSMZ: ACC 530 Oliver He, Jiangan Xie L-1236 MCF12A cell MCF12A Oliver He, Jiangan Xie ATCC: CRL-10782 LCL-2082 MEC-1 cell LCL-1089 Oliver He, Jiangan Xie MEC-1 DSMZ: ACC 497 MEC-2 cell LCL-1090 Oliver He, Jiangan Xie MEC-2 DSMZ: ACC 500 MLMA cell JCRB: JCRB0146 LCL-1091 Oliver He, Jiangan Xie MLMA Mo-T cell COSMIC: COSMIC ID:908149 Mo-T LCL-1096 Oliver He, Jiangan Xie MY-M12 cell MY-M12 JCRB: JCRB0158.1 Oliver He, Jiangan Xie LCL-1002 MY-M13 cell MY-M13 Oliver He, Jiangan Xie LCL-1003 JCRB: JCRB0158.2 NALM-19 cell LCL-1093 Oliver He, Jiangan Xie DSMZ: ACC 522 NALM-19 ROS-50 cell DSMZ: ACC 557 LCL-1094 Oliver He, Jiangan Xie ROS-50 SUM52PE cell SUM52PE LCL-2071 Asterandbio: Oliver He, Jiangan Xie SUP-HD1 cell SUP-HD1 LCL-2014 Oliver He, Jiangan Xie DSMZ: ACC 574 T47DKBLUC cell Oliver He, Jiangan Xie ATCC: CRL-2865 T47DKBLUC LCL-2064 RCB1960 cell LCL-1788 Originator: Miyagiwa, M. (Okayama Univ.) A immortal human cell line cell that has the characteristics: Human bile duct carcinoma. This cell line produces carbohydrate antigen 19/9 in serum-free medium. TKG0389(Deposited from Tohoku Univ.). RCB1960 RIKEN Cell bank Team Yongqun He JHSF: JCRB0425 Register: Obinata, Masuo Derived from tissue: bile duct, ascites meta in animal: human. HuCCT1 RCB0202 cell Derived from tissue: epidermoid carcinoma in animal: human. Register: Abe, Shin-ichiro A431 RCB0202 A immortal human cell line cell that has the characteristics: High level of EGF receptor RIKEN Cell bank Team Yongqun He ECACC: 85090402 LCL-1404 RCB1872 cell RCB1872 A immortal human cell line cell that has the characteristics: Human cell line derivd from epidermoid carcinoma. TKG0182 (Deposited from Tohoku Univ.). ECACC: 85090402 A431 Originator: Giard D J, Aaronson S A RIKEN Cell bank Team Yongqun He Register: Obinata, Masuo Derived from tissue: epidermoid carcinoma in animal: human. LCL-1404 RCB1644 cell A immortal human cell line cell that has the characteristics: It was initiated from a malignant gestational choriocarcinoma of the fetal placenta. Need to check response to hormones before use. Back up culture of ECA2687. RCB1644 LCL-1293 Derived from tissue: fetal placenta in animal: human. Register: ECACC ATCC: CCL-98 BeWo RIKEN Cell bank Team Yongqun He RCB1196 cell Sanger: COSMIC ID:910695 Register: Todoroki, T. & Ohno, T. RCB1196 CHEMBL: CHEMBL3308856 CVCL: CVCL_1770 A immortal human cell line cell that has the characteristics: Japanese gallbladder carcinoma established from metastated ascite. Cell growth is slow. LCL-1344 Derived from tissue: gallbladder, ascites meta in animal: human. Originator: Saijo, Kaoru & Kim, Boms RIKEN Cell bank Team Yongqun He TGBC24TKB RCB1129 cell LCL-1343 Originator: Todoroki, T. & Ohno, T. & Kim, B. CVCL: CVCL_1769 CHEMBL: CHEMBL3308852 Register: Todoroki, T. & Ohno, T. Derived from tissue: gallbladder, lymph node meta in animal: human. RIKEN Cell bank Team Yongqun He RCB1129 TGBC1TKB A immortal human cell line cell that has the characteristics: Japanese gallbadder carcinoma metastated to lymph node from the same patient of TGBC2TKB. Cell growth is slow. Sanger: COSMIC ID:909769 RCB0098 cell A immortal human cell line cell that has the characteristics: Lung carcinoma, refer to ATCC CCL185 RCB0098 A549 ATCC: CCL-185 Originator: Giard, D. J. RIKEN Cell bank Team Yongqun He LCL-1601 Derived from tissue: lung in animal: human. Register: Abe, Shin-ichiro RCB0439 cell Derived from tissue: lung in animal: human. Originator: Kataoka, Hiroaki LC-1F RIKEN Cell bank Team Yongqun He Sanger: COSMIC ID:907785 CVCL: CVCL_1372 CHEMBL: CHEMBL3308207 Register: Itoh, Hiroshi EFO: EFO_0002827 A immortal human cell line cell that has the characteristics: Lung Cancer-1/squamous, floating variant, the same patient as RCB0455 LC-1/sq. LCL-1595 RCB0439 RCB0467 cell Register: Terasaki, Takeo RIKEN Cell bank Team Yongqun He A immortal human cell line cell that has the characteristics: Small cell carcinoma, classic type. See Lu-134-A. Derived from tissue: lung in animal: human. Lu-134-B RCB0467 Originator: Terasaki, T. & Shimosato, Y. JHSF: JCRB0169 LCL-1834 RCB0468 cell RIKEN Cell bank Team Yongqun He Lu-135 JHSF: JCRB0170 A immortal human cell line cell that has the characteristics: Small cell carcinoma, variant type Originator: Terasaki, T. & Shimosato, Y. Register: Terasaki, Takeo Derived from tissue: lung in animal: human. LCL-1809 RCB0468 RCB1965 cell LCL-1584 RIKEN Cell bank Team Yongqun He EBC-1 A immortal human cell line cell that has the characteristics: Human lung squamous cell carcinoma cell line. TKG0481(Deposited from Tohoku Univ.). JHSF: JCRB0820 Register: Obinata, Masuo Derived from tissue: lung in animal: human. RCB1965 RCB1313 cell RIKEN Cell bank Team Yongqun He JHSF: JCRB0137 Derived from tissue: lung in animal: human. Register: Kyoizumi, Seishi A immortal human cell line cell that has the characteristics: Japanese lung adenocarcinoma, highly metastatic in SCID mice. Also refer to RCB0444 RCRF-LC-AI. Cell growth is slow. Originator: Terada, Seigo RERF-LC-KJ LCL-1658 RCB1313 ZN RCB1967 cell RIKEN Cell bank Team Yongqun He Register: Obinata, Masuo JHSF: JCRB0079 Derived from tissue: lung in animal: human. RCB1967 LU65 A immortal human cell line cell that has the characteristics: Human lung carcinoma cell line. TKG0442(Deposited from Tohoku Univ.). LCL-1904 RCB1970 cell JHSF: JCRB0829 EFO: EFO_0003141 RCB1970 LK-2 LCL-1587 CHEMBL: CHEMBL3308472 A immortal human cell line cell that has the characteristics: Human lung squamous cell carcinoma cell line.TKG0494 (Deposited from Tohoku Univ.). Originator: Yoshioka, S. & Yamane. M. Derived from tissue: lung in animal: human. CVCL: CVCL_1377 RIKEN Cell bank Team Yongqun He Register: Obinata, Masuo RCB4455 cell PC-9 RIKEN Cell bank Team Yongqun He : MGH-889 Register: Nakamura, Yukio Derived from tissue: lung in animal: human. LCL-1630 Originator: Tsuji, K. & Hayata, Y. A immortal human cell line cell that has the characteristics: Human cell line derived from lung adenocarcinoma cells. Differentiated type. <a href='http://www.brc.riken.go.jp/lab/cell/english/rcb0446_announce.shtml'>Previous name:PC-14(RCB0446) </a> RCB4455 RCB0554 cell CVCL: CVCL_1302 LCL-1778 IA-LM A immortal human cell line cell that has the characteristics: Japanese lung large cell carcinoma RIKEN Cell bank Team Yongqun He Originator: Miyamoto, Tadaaki & Takiguchi,Yuichi Derived from tissue: lung, skin meta in animal: human. RCB0554 Sanger: COSMIC ID:910779 CHEMBL: CHEMBL3308833 Register: Takiguchi, Yuichi RCB1316 cell RIKEN Cell bank Team Yongqun He RCB1316 LCL-1118 CHEMBL: CHEMBL3308188 Derived from tissue: lymph node, B-lymphoma in animal: human. Originator: Miyazawa, Keisuke & Uchida, Yoshiko CVCL: CVCL_1149 Sanger: COSMIC ID:949088 CTB-1 A immortal human cell line cell that has the characteristics: Fas-antigen expressing. Ligation with anti-Fas mAb does not induce apoptosis. Register: Miyazawa, Keisuke RCB1879 cell Originator: Ravid, Z. LCL-2062 PEER A immortal human cell line cell that has the characteristics: Human T cell line derived from acute T cell leukemia. TKG0377 (Deposited from Tohoku Univ.). Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He ACC 6 Derived from tissue: lymphoid,T-leukemia in animal: human. RCB1879 RCB0749 cell A immortal human cell line cell that has the characteristics: Human fibrous histiocytoma. Showing fibroblastic- and histiocytic features. CVCL: CVCL_1407 MFH-ino LCL-1753 RCB0749 Derived from tissue: maxilla in animal: human. Sanger: COSMIC ID:925343 CHEMBL: CHEMBL3308269 Register: Takahashi, Kikuo Originator: Takahashi, Kikuo RIKEN Cell bank Team Yongqun He RCB2104 cell CHEMBL: CHEMBL3308818 RCB2104 HuO-3N1 Originator: Yamane, T. & Sato, J A immortal human cell line cell that has the characteristics: Human cell line derived from osteosarcoma. TKG0452(Deposited from Tohoku Univ.). Derived from tissue: osteosarcoma in animal: human. LCL-1422 Register: Obinata, Masuo CVCL: CVCL_1297 RIKEN Cell bank Team Yongqun He JHSF: JCRB0413 RCB2095 cell PANC-1 RCB2095 LCL-1726 Register: Obinata, Masuo Derived from tissue: pancreas in animal: human. A immortal human cell line cell that has the characteristics: Human cell line derived from pancreatic cancer. Ductal origin. TKG0606(Deposited from Tohoku Univ.) ATCC: CRL-1469 RIKEN Cell bank Team Yongqun He RCB0803 cell RCB0803 Register: Isobe, Yasushi LCL-1998 CHEMBL: CHEMBL3308847 CVCL: CVCL_1450 RIKEN Cell bank Team Yongqun He Derived from tissue: pelvic tumor in animal: human. Originator: Isobe, Yasushi NBsusSR RIKEN: COSMIC ID:925342; Riken RCB0803,RCB0803 A immortal human cell line cell that has the characteristics: Isolated from a patient with hiper dopaminemia andnorepinephrinemia. RCB1635 cell Derived from tissue: pleural effusion in animal: human. K-562 Register: Ichiki, T. Albert RCB1635 A immortal human cell line cell that has the characteristics: Human CML derived cell line. Deposited directly from the institution that has established this cell. ATCC: CCL-243 RIKEN Cell bank Team Yongqun He Originator: Lozzio, C.B. & Lozzio, B.B. LCL-1103 RCB0428 cell Saos-2 Originator: Fogh, J. & Trempe, G RIKEN Cell bank Team Yongqun He ATCC: HTB-85 Derived from tissue: sarcoma in animal: human. A immortal human cell line cell that has the characteristics: Osteogenic sarcoma RCB0428 Register: RCB (Noda, Makoto) LCL-1430 RCB1980 cell Derived from tissue: T acute lymphoblastic leukemia in animal: human. RIKEN Cell bank Team Yongqun He A immortal human cell line cell that has the characteristics: Human cell line derived from T cell leukemia. TKG0563(Deposited from Tohoku Univ.). Register: Obinata, Masuo RCB1980 ATCC: CCL-119 LCL-1012 CCRF-CEM RCB1952 cell CVCL: CVCL_1686 RIKEN Cell bank Team Yongqun He RCB1952 JHSF: JCRB0106 A immortal human cell line cell that has the characteristics: Human neuroblastoma cell line. TKG0460(Deposited from Tohoku Univ.). Derived from tissue: unknown in animal: human. CHEMBL: CHEMBL3308127 LCL-1968 Originator: Kaneko, Y. Register: Obinata, Masuo SCCH-26 RCB0480 cell Originator: Gilbert, F. A immortal somatic nervous system-derived cell line cell that has the characteristics: N-myc gene unamplified tumor. Cell growth is slow. Register: Nishi, Yoshisuke CHEMBL: CHEMBL3308799 RIKEN Cell bank Team Yongqun He RCB0480 Derived from tissue: nervous system in animal: human. LCL-1999 CVCL: CVCL_1448 ECACC: 99072802 NB69 RCB0486 cell RCB0486 LCL-1973 Originator: Schlesinger, H. R. A immortal somatic nervous system-derived cell line cell that has the characteristics: N-myc gene amplification. Cell growth is slow. DSMZ: ACC 304 CHP-126 RIKEN Cell bank Team Yongqun He Register: Nishi, Yoshisuke Derived from tissue: neuroblastoma in animal: human. RCB2108 cell Derived from tissue: neuroblastoma in animal: human. CHEMBL: CHEMBL3308211 Register: Obinata, Masuo JHSF: JCRB0833 A immortal somatic nervous system-derived cell line cell that has the characteristics: Human cell line derived from neuroblastoma. TKG0448(Deposited from Tohoku Univ.). NH-12 RCB2108 LCL-1978 Originator: Hiyama, E. & Nakamura, N. RIKEN Cell bank Team Yongqun He CVCL: CVCL_1605 RCB0426 cell A immortal somatic nervous system-derived cell line cell that has the characteristics: Neuroblastoma, a target in CTL assay ATCC: HTB-11 Register: RCB (Noda, Makoto) LCL-1971 SK-N-SH Originator: Biedler, J. L. Derived from tissue: neuroblastoma in animal: human. RIKEN Cell bank Team Yongqun He RCB0426 RCB2280 cell Originator: Sasaki, Kaoru HCE-T RIKEN Cell bank Team Yongqun He Derived from tissue: cornea in animal: human. Register: Sasaki, Kaoru CVCL: CVCL_1272 RCB2280 A immortal cornea-derived cell line cell that has the characteristics: SV40-Adeno vector transformed cornea cells. 64kD keratin producing. Choleratoxin-free medium. CHEMBL: CHEMBL3308200 Sanger: COSMIC ID:907049 LCL-1047 RCB1384 cell RIKEN Cell bank Team Yongqun He RCB1384 CHEMBL: CHEMBL3308200 LCL-1047 A immortal cornea-derived cell line cell that has the characteristics: This cell line is provided only in Japan. Sanger: COSMIC ID:907049 Register: Sasaki, Kaoru HCE-T CVCL: CVCL_1272 Originator: Sasaki, Kaoru Derived from tissue: cornea in animal: human. RCB1701 cell A immortal human lymphocyte cell line cell that has the characteristics: Human cell line derived from p180-BCR-ABL dependent leukemia. Derived from tissue: peripheral blood lymphocytes in animal: human. MY Register: Inokuchi, Koiti RIKEN Cell bank Team Yongqun He RCB1701 LCL-1001 JCRB0158.0 Originator: Inokuchi, Koiti RCB1829 cell A immortal mouse embryo-derived cell line cell that has the characteristics: Embryonal cell line derived from wild mouse. Sensitive to leukemia viruses. Register: Kubo, Yoshinao RIKEN Cell bank Team Yongqun He Derived from tissue: embryo in animal: mouse, wild. LCL-1944 SC-1 CRL-8756 RCB1829 RCB0778 cell Register: Mitsuhashi, Maki RCB0778 CVCL: CVCL_1151 Derived from tissue: colon in animal: human. A immortal human colon-derived cell line cell that has the characteristics: Colon carcinoma. CEA-positive, nude mouse-transplantable. CHEMBL: CHEMBL3308161 RIKEN Cell bank Team Yongqun He CW-2 Originator: Mitsuhashi, Maki Sanger: COSMIC ID:910554 LCL-1190 RCB1193 cell RCB1193 Derived from tissue: colon in animal: human. DSMZ: ACC 144 A immortal human colon-derived cell line cell that has the characteristics: Described to produce serotonin, epinephrine. LCL-1174 COLO-320 Register: DSMZ RIKEN Cell bank Team Yongqun He RCB1639 cell RIKEN Cell bank Team Yongqun He Derived from tissue: colon, supraclavicular meta in animal: human. LoVo RCB1639 A immortal human colon-derived cell line cell that has the characteristics: CEA-producing colon adenocarcinoma. Back up culture of ECA2739. Cell growth is slow. ATCC: CCL-229 LCL-1181 Register: ECACC RCB0763 cell Register: Nakatu, Syouji GI-1 CVCL: CVCL_1231 A immortal human brain-derived cell line cell that has the characteristics: Human glioma separated from gliosarcoma. Originator: Iwasaki, Kouji RIKEN Cell bank Team Yongqun He RCB0763 Sanger: COSMIC ID:906871 LCL-1379 CHEMBL: CHEMBL3308167 Derived from tissue: brain in animal: human. RCB1954 cell RIKEN Cell bank Team Yongqun He LCL-1357 RCB1954 T98G A immortal human brain-derived cell line cell that has the characteristics: Human cell line derived from glioblastoma multiforme (Caucasian). Hyperpentaploid chromosome count. TKG0471(Deposited from Tohoku Univ.). Register: Obinata, Masuo Derived from tissue: brain in animal: human. ATCC: CRL-1690 RCB2530 cell A immortal human brain-derived cell line cell that has the characteristics: Human cell line derived from glioblastoma. TKG0183(Deposited from Tohoku Univ.). ATCC: CRL-1620 A172 RIKEN Cell bank Team Yongqun He Originator: Giard, D. J. Derived from tissue: brain in animal: human. Register: Fukuda, Hiroshi LCL-1348 RCB2530 RCB0270 cell A immortal human brain-derived cell line cell that has the characteristics: Glioma, S-100 Protein producing. Cell growth is slow. Originator: Miyake, Etsuo KG-1-C JHSF: JCRB0236 RIKEN Cell bank Team Yongqun He LCL-1801 RCB0270 Derived from tissue: brain in animal: human. Register: Miyake, Etsuo RCB0736 cell RCB0736 A immortal human skin-derived cell line cell that has the characteristics: Malignant trichilemmal cyst cells. Strongly laminin positive on cell surface. Serum-free culturable. CHEMBL: CHEMBL3308190 Register: Katayama, Hiroshi Sanger: COSMIC ID:906841 CVCL: CVCL_1172 Derived from tissue: skin in animal: human. DJM-1 Originator: Yaoita, Hideo LCL-1405 RIKEN Cell bank Team Yongqun He RCB0991 cell RIKEN Cell bank Team Yongqun He A immortal human skin-derived cell line cell that has the characteristics: Human melanoma producing melanin up to 50 PDL. Backup of ECA88030401. G-361 ATCC: CRL-1424 Derived from tissue: skin in animal: human. RCB0991 Register: ECACC LCL-1246 RCB1939 cell CHEMBL: CHEMBL3307267 JHSF: JCRB0834 Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He Derived from tissue: stomach in animal: human. A immortal human stomach-derived cell line cell that has the characteristics: Human cell line derived from signet ring cell carcinoma of stomach. TKG0449 (Deposited from Tohoku Univ.). CVCL: CVCL_3082 NUGC-4 RCB1939 LCL-2001 RCB0555 cell A immortal human stomach-derived cell line cell that has the characteristics: Stomach cancer (Borrmann IV). Mutin, CA19-9, CEA, alphafetoprotein positive Cell growth is slow. CVCL: CVCL_1228 Derived from tissue: stomach in animal: human. RCB0555 GCIY LCL-1891 CHEMBL: CHEMBL3308825 RIKEN Cell bank Team Yongqun He Originator: Nozue, Mutsumi Register: Nozue, Mutsumi RIKEN: COSMIC ID:906869; Riken RCB0555,RCB0555 RCB0983 cell CHEMBL: CHEMBL3308191 LCL-1897 A immortal human stomach-derived cell line cell that has the characteristics: Small cell gastrointestinal carcinoma with c-myc overexpression. Cell growth is slow. RIKEN Cell bank Team Yongqun He ECC10 Originator: Ishihara, Noriko RIKEN: COSMIC ID:906848; Riken RCB0983,RCB0983 CVCL: CVCL_1188 RCB0983 Register: Motoyama, Teiichi Derived from tissue: stomach, liver meta in animal: human. RCB1001 cell RCB1001 A immortal human stomach-derived cell line cell that has the characteristics: Poorly differentiated gastric adenocarcinoma. Producing high level of CEA. Originator: Hojo, Haruto RIKEN Cell bank Team Yongqun He Register: Motoyama, Teiichi JHSF: JCRB0254 MKN45 LCL-1535 Derived from tissue: stomach, liver meta in animal: human. RCB1002 cell RCB1002 JHSF: JCRB0255 LCL-1536 MKN74 Register: Motoyama, Teiichi RIKEN Cell bank Team Yongqun He Derived from tissue: stomach, liver meta in animal: human. Originator: Hojo, Haruo A immortal human stomach-derived cell line cell that has the characteristics: Moderately differentiated adenocarcinoma. Once they were hypodiploids. Cell growth is slow. RCB0500 cell RIKEN Cell bank Team Yongqun He LCL-1882 Register: Kimoto, Tetsuo Originator: Akagi, Tadaatsu A immortal human stomach-derived cell line cell that has the characteristics: Gastric cancer undifferentiated, mucin producing Derived from tissue: stomach, lymph node meta in animal: human. RCB0500 ECACC: 94042256 HGC-27 RCB1148 cell Derived from tissue: stomach, lymph node meta in animal: human. A immortal human stomach-derived cell line cell that has the characteristics: Japanese gastric cancer, lymph node metastated. CVCL: CVCL_1768 CHEMBL: CHEMBL3308557 Register: Ohno, T. & Todoroki, T. LCL-1892 RIKEN: RCB1148,COSMIC ID:909770; Riken RCB1148 RCB1148 Originator: Kim, B. & Ohno, Tadao RIKEN Cell bank Team Yongqun He TGBC11TKB RCB1003 cell LCL-1917 RCB1003 JHSF: JCRB0252 A immortal human stomach-derived cell line cell that has the characteristics: Potentially differentiatable to both direction of adenomatous and squamous epithelial cells. RIKEN Cell bank Team Yongqun He Derived from tissue: stomach, lymph node meta in animal: human. Originator: Hojo, Haruto MKN1 Register: Motoyama, Teiichi RCB0999 cell Register: Motoyama, Teiichi A immortal human stomach-derived cell line cell that has the characteristics: c-erbB-2 expressing gastric adenocarcinoma. Differentiated type. JHSF: JCRB1025 LCL-1885 Originator: Hojo, Haruto RCB0999 Derived from tissue: stomach, lymph node meta in animal: human. MKN7 RIKEN Cell bank Team Yongqun He RCB1009 cell A immortal human stomach-derived cell line cell that has the characteristics: Small cell gastrointestinal carcinoma showing creatine kinase-BB and aromatic L-amino-acid decarboxy. Cell growth is slow. CHEMBL: CHEMBL3308192 ECC12 Originator: Ishihara, Noriko RIKEN Cell bank Team Yongqun He Register: Motoyama, Teiichi Sanger: COSMIC ID:906849 LCL-1898 RCB1009 CVCL: CVCL_1189 Derived from tissue: stomach, subcutis in animal: human. RCB1890 cell LCL-1428 RCB1890 A immortal human bone element-derived cell line cell that has the characteristics: Osteosarcoma cell line derived from human. High yield of IFN production by induction with poly IC, cyclohexmide, actinomycin D. Antigenically, MG-63 IFN is closely related to human fibroblast IFN. TKG0294 (Deposited from Tohoku Univ.). Derived from tissue: bone in animal: human. Register: Obinata, Masuo MG-63 ECACC: 86051601 RIKEN Cell bank Team Yongqun He RCB0992 cell ECACC: 87070202 HOS LCL-1421 Register: ECACC RIKEN Cell bank Team Yongqun He A immortal human bone element-derived cell line cell that has the characteristics: Sensitive to further transformation with both virus and chemicals. Backup of ECA87070202. Derived from tissue: bone in animal: human. RCB0992 RCB1032 cell LCL-1432 A immortal human bone element-derived cell line cell that has the characteristics: Osteoid producing in vitro and in nude mice. Cell growth is slow. RIKEN Cell bank Team Yongqun He Originator: Hotta, Tetsuo & Motoyama, Teiichi CVCL: CVCL_1610 NOS-1 RCB1032 CHEMBL: CHEMBL3308836 Derived from tissue: bone in animal: human. Sanger: COSMIC ID:925345 Register: Motoyama, Teiichi RCB0431 cell Derived from tissue: bladder in animal: human. RIKEN Cell bank Team Yongqun He Originator: Bubenick, J. Register: RCB (Noda, Makoto) T24 LCL-1709 RCB0431 ATCC: HTB-4 A immortal human urinary bladder-derived cell line cell that has the characteristics: Bladder transitional-cell carcinoma RCB2536 cell ATCC: HTB-4 A immortal human urinary bladder-derived cell line cell that has the characteristics: Human cell line derived from bladder cancer. Transitional cell carcinoma. TKG0443 (Deposited from Tohoku Univ.). RCB2536 Register: Fukuda, Hiroshi T24 Derived from tissue: bladder in animal: human. Originator: Bubenick, J. LCL-1709 RIKEN Cell bank Team Yongqun He RCB1191 cell A immortal human urinary bladder-derived cell line cell that has the characteristics: Described to produce SCF, IL-1, IL-3, IL-6, G-CSF, GM-CSF, etc. ATCC: HTB-9 5637 Register: DMSZ Derived from tissue: bladder in animal: human. RCB1191 LCL-1702 RIKEN Cell bank Team Yongqun He RCB1648 cell RCB1648 RIKEN Cell bank Team Yongqun He Derived from tissue: liver in animal: human. LCL-1925 Register: ECACC Hep G2 ATCC: HB-8065 A immortal human liver-derived cell line cell that has the characteristics: hepatocellular carcinoma. Produce alpha-fetoprotein, albumin, etc. Back up of ECA2870. Almost equal to RCB0459, but the restriction is a. <a href='http://www.brc.riken.jp/lab/cell/english/hep_g2.shtml'>Information</a> RCB1886 cell RIKEN Cell bank Team Yongqun He Derived from tissue: liver in animal: human. Register: Obinata, Masuo ATCC: HB-8065 A immortal human liver-derived cell line cell that has the characteristics: Human cell line derived from hepatocyte carcinoma. TKG0205 (Deposited from Tohoku Univ.). <a href='http://www.brc.riken.jp/lab/cell/english/hep_g2.shtml'>Information</a> Hep G2 LCL-1925 RCB1886 RCB1192 cell Derived from tissue: breast in animal: human. Register: DMSZ MDA-MB-453 ATCC: HTB-131 RIKEN Cell bank Team Yongqun He LCL-1485 A immortal human breast-derived cell line cell that has the characteristics: Human breast carcinoma established from an effusion. RCB1192 RCB1904 cell RCB1904 Register: Obinata, Masuo Originator: Soule H.D. A immortal human breast-derived cell line cell that has the characteristics: Human cell line derived from breast adenocarcinoma. TKG0479 (Deposited from Tohoku Univ.). MCF7 Derived from tissue: brest, pleural fluid in animal: human. RIKEN Cell bank Team Yongqun He ATCC: HTB-22 LCL-1460 RCB1702 cell Originator: Inokuchi, Koiti RCB1702 A immortal human spleen-derived cell line cell that has the characteristics: Human cell line derived from splenic B cell lymphoma. Register: Inokuchi, Koiti LCL-1952 Derived from tissue: spleen in animal: human. RIKEN Cell bank Team Yongqun He SLVL JHSF: JCRB0159 RCB0735 cell Originator: Kinouchi, Toshiaki Register: Kinouchi, Toshiaki A immortal human kidney-derived cell line cell that has the characteristics: Renal tumor cell from a Japanese. Transplantable to nude mice. RCB0735 OS-RC-2 Derived from tissue: kidney in animal: human. CHEMBL: CHEMBL3308274 Sanger: COSMIC ID:909250 CVCL: CVCL_1626 LCL-1768 RIKEN Cell bank Team Yongqun He RCB1151 cell CVCL: CVCL_1647 LCL-1769 Sanger: COSMIC ID:909974 Register: Ohno, Tadao RIKEN Cell bank Team Yongqun He Originator: Hashizaki, K. A immortal human kidney-derived cell line cell that has the characteristics: Kidney carcinoma from a Japanese patient. Cell growth is slow. RCB1151 RCC10RGB CHEMBL: CHEMBL3308302 Derived from tissue: kidney in animal: human. RCB1963 cell VMRC-RCW RIKEN Cell bank Team Yongqun He RCB1963 Originator: Akiyama, M. Register: Obinata, Masuo JHSF: JCRB0813 Derived from tissue: kidney in animal: human. LCL-1759 A immortal human kidney-derived cell line cell that has the characteristics: Human renal cell carcinoma cell line. TKG0447(Deposited from Tohoku Univ.). RCB0007 cell RCB0007 Originator: Gey, G. O. et al. RIKEN Cell bank Team Yongqun He LCL-1512 Register: Soeda, Eiichi ATCC: CCL-2 A immortal human uterine cervix-derived cell line cell that has the characteristics: Just like ATCC CCL 2, HeLa HeLa Derived from tissue: cervix in animal: human. RCB1892 cell RCB1892 LCL-1804 CHEMBL: CHEMBL3308786 Derived from tissue: cervix in animal: human. A immortal human uterine cervix-derived cell line cell that has the characteristics: Cervical carcinoma cell line derived from human. TA-4, CA-4, TPA, placental ALP are positive. Regan isoenzyme producing. p53 normal, p51 mutation (+), HLA-A 2402/.TKG0462(Deposited from Tohoku Univ.). SKG-IIIa Register: Obinata, Masuo Originator: Nozawa, S. CVCL: CVCL_1704 RIKEN Cell bank Team Yongqun He JHSF: JCRB0232 RCB2106 cell A immortal human uterine cervix-derived cell line cell that has the characteristics: Human cell line derived from cervical cancer. TKG0437(Deposited from Tohoku Univ.). ME-180 Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He ATCC: HTB-33 LCL-1305 RCB2106 Originator: Sykes, J. A. Derived from tissue: cervix in animal: human. RCB1947 cell Derived from tissue: cervix in animal: human. Ca Ski RIKEN Cell bank Team Yongqun He ECACC: 87020501 RCB1947 LCL-1541 Register: Obinata, Masuo Originator: Pattillo, R. A. A immortal human uterine cervix-derived cell line cell that has the characteristics: Human cell line derived from uterine cervical epidermoid carcinoma. TKG0366(Deposited from Tohoku Univ.). RCB0753 cell LCL-1546 Register: Ueda, Masatsugu RCB0753 Originator: Ueda, Masatsugu RIKEN Cell bank Team Yongqun He A immortal human uterine cervix-derived cell line cell that has the characteristics: Japanese cervix squamous cell carcinoma. Once said TA-4 positive. CVCL: CVCL_1623 Sanger: COSMIC ID:949154 OMC-1 Derived from tissue: cervix, Virchow's lymph node in animal: human. CHEMBL: CHEMBL3308213 RCB1909 cell RCB1909 A immortal human thyroid gland-derived cell line cell that has the characteristics: Human thyroid anaplastic carcinoma derived cell line. TKG0446 (Deposited from Tohoku Univ.). DSMZ: ACC 133 RIKEN Cell bank Team Yongqun He Derived from tissue: thyroid in animal: human. 8305C Register: Obinata, Masuo Originator: Hirooka T and miller C. LCL-1685 RCB2103 cell Derived from tissue: thyroid gland in animal: human. Originator: Nakamura, N. RIKEN Cell bank Team Yongqun He 8505C RCB2103 A immortal human thyroid gland-derived cell line cell that has the characteristics: Human cell line derived from thyroid cancer. Poorly differentiated papillary adenocarcinoma. TKG0439(Deposited from Tohoku Univ.). Register: Obinata, Masuo LCL-1686 DSMZ: ACC 219 RCB1933 cell NALM-6 Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He ACC 128 Derived from tissue: blood in animal: human. LCL-1007 RCB1933 A immortal human blood cell line cell that has the characteristics: Human cell line derived from B cell leukemia. TKG0413(Deposited from Tohoku Univ.). RCB0016 cell A immortal human blood cell line cell that has the characteristics: T cell leukemia LCL-1914 ATCC: CCL-120.1 CCRF-HSB-2 Originator: G.E. Foley et al. Derived from tissue: blood in animal: human. RIKEN Cell bank Team Yongqun He Register: Todokoro, Kazuo RCB0016 RCB0497 cell RCB0497 RIKEN Cell bank Team Yongqun He Originator: Kishi, Kenji KU812F LCL-1108 A immortal human blood cell line cell that has the characteristics: Chronic myelogeneous leukemia, subclone of RCB0495 KU812. Derived from tissue: blood in animal: human. Register: Mizusawa, Hiroshi ATCC: CRL-2101 RCB0540 cell A immortal human blood cell line cell that has the characteristics: Acute lymphatic leukemia Register: Ohyashiki, Kazuma Originator: Ohyashiki, Kazuma Derived from tissue: blood in animal: human. CHEMBL: CHEMBL3308233 RCB0540 CVCL: CVCL_1242 Sanger: COSMIC ID:949153 LCL-1046 RIKEN Cell bank Team Yongqun He HAL-01 RCB1182 cell Originator: Soheir S. El-Sonbaty RIKEN Cell bank Team Yongqun He GR-ST CVCL: CVCL_1236 A immortal human blood cell line cell that has the characteristics: RCB1181 ST cells transformed with human G-CSF receptor cDNA. Responds to G-CSF. Register: Tsuchiya, Hiroyuki Derived from tissue: blood in animal: human. Sanger: COSMIC ID:906877 RCB1182 CHEMBL: CHEMBL3308529 LCL-1045 RCB1440 cell A immortal human blood cell line cell that has the characteristics: Adult T-cell leukemia. HTLV-1 pro-virus DNA(+). LCL-1025 Derived from tissue: blood in animal: human. Originator: Naoe, Tomoki ATN-1 CVCL: CVCL_1073 RIKEN Cell bank Team Yongqun He CHEMBL: CHEMBL3308183 Sanger: COSMIC ID:910687 Register: Naoe, Tomoki RCB1440 RCB0495 cell KU812 LCL-1106 RCB0495 RIKEN Cell bank Team Yongqun He A immortal human blood cell line cell that has the characteristics: Chronic myelogeneous leukemia, Ph1 chromosome (+),basophi-like cells. ATCC: CRL-2099 Register: Mizusawa, Hiroshi Originator: Kishi, Kenji Derived from tissue: blood in animal: human. RCB0206 cell A immortal human blood cell line cell that has the characteristics: T cell leukemia, the same patient as RCB1164 MOLT-3. LCL-1019 Originator: Minowada, J. Derived from tissue: blood in animal: human. Register: ECACC RCB0206 MOLT-4 ATCC: CRL-1582 RIKEN Cell bank Team Yongqun He RCB1936 cell Originator: Minowada, J. LCL-1031 CVCL: CVCL_2792 RIKEN Cell bank Team Yongqun He JHSF: JCRB0021 MOLT-4F CHEMBL: CHEMBL3307263 RCB1936 Derived from tissue: blood in animal: human. Register: Obinata, Masuo A immortal human blood cell line cell that has the characteristics: Human T leukemic cell line (CD4+). CR2 receptor (+). TKG0229(Deposited from Tohoku Univ.). RCB1189 cell Register: DMSZ LCL-1072 THP-1 ATCC: TIB-202 A immortal human blood cell line cell that has the characteristics: Differentates to macrophage-like cells after treatment with phorbol ester. The variant subline (RCB2128 A-THP-1). RIKEN Cell bank Team Yongqun He Derived from tissue: blood in animal: human. RCB1189 RCB0496 cell RIKEN Cell bank Team Yongqun He LCL-1107 KU812E Derived from tissue: blood in animal: human. RCB0496 ATCC: CRL-2100 Register: Mizusawa, Hiroshi A immortal human blood cell line cell that has the characteristics: Chronic myelogenous leukemia , subclone of RCB0495 KU812. Originator: Kishi, Kenji RCB0256 cell A immortal human blood cell line cell that has the characteristics: Typical human B cell leukemia. BALL-1 RIKEN Cell bank Team Yongqun He Derived from tissue: blood in animal: human. Register: Maekawa, T. (Ito,F.) JCRB0071 CHEMBL: CHEMBL3308839 CVCL: CVCL_1075 RCB0256 LCL-1005 RCB1882 cell RCB1882 Derived from tissue: blood in animal: human. RIKEN Cell bank Team Yongqun He CHEMBL: CHEMBL3308839 JCRB0071 CVCL: CVCL_1075 LCL-1005 A immortal human blood cell line cell that has the characteristics: Human cell line derived from B cell leukemia. TKG0467 (Deposited from Tohoku Univ.). Originator: Miyoshi, I. & Hiraki, S. Register: Obinata, Masuo BALL-1 RCB1938 cell RCB1938 Originator: Hirose, M. A immortal human blood cell line cell that has the characteristics: Human cell line derived from T cell leukemia. TKG0463(Deposited from Tohoku Univ.). LCL-1038 Register: Obinata, Masuo JHSF: JCRB0094 P30/OHK RIKEN Cell bank Team Yongqun He Derived from tissue: Peripheral blood in animal: human. RCB1894 cell Register: Obinata, Masuo Originator: Nishihira, Tetsuro Sanger: COSMIC ID:753621 LCL-1564 CHEMBL: CHEMBL3308178 RIKEN Cell bank Team Yongqun He TE-1 A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Squamous cell carcinoma. TKG0462(Deposited from Tohoku Univ.). RCB1894 CVCL: CVCL_1759 Derived from tissue: esophagus in animal: human. RCB1951 cell CHEMBL: CHEMBL3308221 CVCL: CVCL_1763 RCB1951 TE-15 Originator: Nishihira, Tetsuro (Akaishi, T.) Derived from tissue: esophagus in animal: human. A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer (highly differentiated squamous cell carcinoma). Not transplantable to nude mouse. TKG0266 (Deposited from Tohoku Univ.). LCL-1568 Sanger: COSMIC ID:753614 Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He RCB2098 cell Originator: Nishihira, Tetsuro Derived from tissue: esophagus in animal: human. CVCL: CVCL_1766 RCB2098 Register: Obinata, Masuo CHEMBL: CHEMBL3308525 TE-8 Sanger: COSMIC ID:753623 A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Moderately differentiated squamous cell carcinoma. TKG0259(Deposited from Tohoku Univ.). RIKEN Cell bank Team Yongqun He LCL-1571 RCB2099 cell TE-10 RIKEN Cell bank Team Yongqun He LCL-1565 Register: Obinata, Masuo A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Highly differentiated squamous cell carcinoma. TKG0261(Deposited from Tohoku Univ.). CHEMBL: CHEMBL3308218 Sanger: COSMIC ID:753622 CVCL: CVCL_1760 Derived from tissue: esophagus in animal: human. RCB2099 Originator: Nishihira, Tetsuro RCB2100 cell Register: Obinata, Masuo CVCL: CVCL_1761 Originator: Nishihira, Tetsuro A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Moderately differentiated squamous cell carcinoma. TKG0262(Deposited from Tohoku Univ.). Sanger: COSMIC ID:946354 TE-11 Derived from tissue: esophagus in animal: human. RIKEN Cell bank Team Yongqun He LCL-1566 CHEMBL: CHEMBL3308219 RCB2100 RCB1949 cell RCB1949 Derived from tissue: esophagus in animal: human. CVCL: CVCL_1764 Sanger: COSMIC ID:735784 Originator: Nishihira, Tetsuro RIKEN Cell bank Team Yongqun He A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from poorly differntiated esophageal squamous cell carcinoma. Not transplantable to nude mouse. TKG0256 (Deposited from Tohoku Univ.). Register: Obinata, Masuo LCL-1569 CHEMBL: CHEMBL3308179 TE-5 RCB1950 cell LCL-1570 RIKEN Cell bank Team Yongqun He Derived from tissue: esophagus in animal: human. Register: Obinata, Masuo CHEMBL: CHEMBL3308180 TE-6 RCB1950 CVCL: CVCL_1765 A immortal human esophagus-derived cell line cell that has the characteristics: Highly differentiated squamous carcinoma (esophagus), not transplantable to nude mouse. 　A culture submitted to the Cell Resource Center for Biomedical Research was found to be contaminated with mycoplasma. Progeny were cured by Treatments with BM Cyclin and MC210. TKG0257 (Deposited from Tohoku Univ.). Sanger: COSMIC ID:946355 Originator: Nishihira, Tetsuro RCB0774 cell Derived from tissue: esophagus, lymph node meta in animal: human. Register: Sato, Kanji LCL-1151 RCB0774 CHEMBL: CHEMBL3308289 Originator: Sato, Kanji Sanger: COSMIC ID:753555 CVCL: CVCL_1187 RIKEN Cell bank Team Yongqun He EC-GI-10 A immortal human esophagus-derived cell line cell that has the characteristics: Produce hypercalcemia in nude mice. PTH-related protein, IL-1alpha producing. RCB1988 cell RCB1988 A immortal human esophagus-derived cell line cell that has the characteristics: Human esophageal squamous cell carcinoma (poorly differentiated) cell line. Not transplantable to nude mouse. TKG0260 (Deposited from Tohoku Univ.). Sanger: COSMIC ID:946353 RIKEN Cell bank Team Yongqun He Originator: Nishihira, T. (Sekine, Y.) LCL-1572 Derived from tissue: esophagus, pleural effusion in animal: human. CVCL: CVCL_1767 CHEMBL: CHEMBL3308181 Register: Obinata, Masuo TE-9 RCB1976 cell CVCL: CVCL_1102 LCL-2033 Ca9-22 RIKEN Cell bank Team Yongqun He JHSF: JCRB0625 A immortal human gingiva-derived cell line cell that has the characteristics: Human gingival carcinoma cell line. Expressing remarkable EGF receptor. HLA-A 2/24. TKG0485(Deposited from Tohoku Univ.). CHEMBL: CHEMBL3308714 RCB1976 Derived from tissue: gingiva in animal: human. Register: Obinata, Masuo RCB0508 cell Register: Saotome, Kouichi Originator: Saotome, K. & Sibukawa, A. H-EMC-SS RCB0508 RIKEN Cell bank Team Yongqun He ECACC: 94042258 Derived from tissue: muscle in animal: human. A immortal human muscle cell line cell that has the characteristics: Extraskeltal myxoid chondrosarcoma LCL-1458 RCB1945 cell CHEMBL: CHEMBL3308482 JHSF: JCRB0622 HSC-2 A immortal human mouth-derived cell line cell that has the characteristics: Human cell line derived from oral squamous cell carcinoma occurred in 69-yo, male patient. HLA-A 24/. TKG0487 (Deposited from Tohoku Univ.). Originator: Hiraki S RCB1945 disease: oral cavity cancer,squamous cell carcinoma Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He Derived from tissue: mouth in animal: human. LCL-1206 CVCL: CVCL_1287 RCB2102 cell LCL-1202 RCB2102 RIKEN Cell bank Team Yongqun He Originator: Miyauchi, T. HO-1-u-1 JHSF: JCRB0828 disease: oral cavity cancer,squamous cell carcinoma Derived from tissue: mouth floor in animal: human. Register: Obinata, Masuo A immortal human mouth-derived cell line cell that has the characteristics: Human cell line derived from squamous cell carcinoma at mouth floor. TKG0455(Deposited from Tohoku Univ.). RCB0489 cell CHEMBL: CHEMBL3308176 RCB0489 Derived from tissue: testis in animal: human. CVCL: CVCL_1604 Originator: Motoyama, Teiichi NEC8 RIKEN Cell bank Team Yongqun He LCL-1900 JHSF: JCRB0250 Register: Motoyama, Teiichi A immortal human testis-derived cell line cell that has the characteristics: Embryonal carcinoma, testis. RCB0982 cell Sanger: COSMIC ID:906850 CHEMBL: CHEMBL3308162 RCB0982 ECC4 Originator: Ishihara, Noriko Register: Motoyama, Teiichi A immortal human intestine-derived cell line cell that has the characteristics: Small-cell gastrointestinal carcinoma. High levels of creatine kinase brain isoenzyme. Cell growth is slow. LCL-1115 RIKEN Cell bank Team Yongqun He Derived from tissue: intestine in animal: human. CVCL: CVCL_1190 RCB1953 cell A immortal human adrenal gland-derived cell line cell that has the characteristics: Human cell line derived from neuroblastoma. Dibuty-cAMP (1 mM) induces differentiation. TKG0486(Deposited from Tohoku Univ.). RIKEN Cell bank Team Yongqun He Originator: Miyake, S. NB-1 Register: Obinata, Masuo JHSF: JCRB0621 LCL-1977 RCB1953 Derived from tissue: sympatho adrenal cell in animal: human. RCB2135 cell Register: Obinata, Masuo Derived from tissue: ovary, ascites meta in animal: human. A immortal human ovary-derived fibroblast cell line cell that has the characteristics: Human cell line derived from adenocarcinoma of ovary. TKG0602(Deposited from Tohoku Univ.). RIKEN Cell bank Team Yongqun He RCB2135 Originator: Hamilton T.C. LCL-1522 NIH:OVCAR-3 ATCC: HTB-161 RCB1154 cell A immortal human ovary-derived fibroblast cell line cell that has the characteristics: Granulosa cell tumor. Possible to produce progesterone after HCG addition. Cell growth is slow. Originator: Nishi, Yoshihiro & Nawata, Hajime Sanger: COSMIC ID:924186 Derived from tissue: ovary, peritoneum in animal: human. CHEMBL: CHEMBL3308155 LCL-1297 KGN CVCL: CVCL_0375 Register: Nishi, Y. & Nawata, H. RIKEN Cell bank Team Yongqun He RCB1154 RCB2145 cell Register: Obinata, Masuo RIKEN Cell bank Team Yongqun He PC-3 Derived from tissue: prostate, bone meta in animal: human. RCB2145 ATCC: CRL-1435 A immortal human prostate gland-derived cell line cell that has the characteristics: Human cell line derived from bone metastasis of prostatic cancer. TKG0600(Deposited from Tohoku Univ.). LCL-1299 RCB0478 cell Register: Nishi, Yoshisuke A immortal human bone marrow-derived cell line cell that has the characteristics: N-myc gene amplification RCB0478 NB16 Derived from tissue: bone marrow in animal: human. Originator: Gilbert, F. RIKEN Cell bank Team Yongqun He RIKEN: COSMIC ID:910929; Riken RCB0478,RCB0478 LCL-1993 RCB2084 cell RCB2084 Derived from tissue: bone marrow in animal: human. CVCL: CVCL_1736 Originator: Hiraki A immortal human bone marrow-derived cell line cell that has the characteristics: Human T-cell line derived from acute lynphblastic leukemia. TKG0251 (Deposited from Tohoku Univ.). LCL-1024 Register: Obinata, Masuo DSMZ: ACC 521 RIKEN Cell bank Team Yongqun He CHEMBL: CHEMBL3308541 TALL-1 RCB1166 cell KG-1 Register: DSMZ Derived from tissue: bone marrow in animal: human. A immortal human bone marrow-derived cell line cell that has the characteristics: Human acute myeloid leukemia. The variant subline (RCB1928 KG-1a) CD3-,CD13+,CD14-,CD15+,CD19-,CD33+ LCL-1056 RCB1166 ATCC: CCL-246 RIKEN Cell bank Team Yongqun He RCB1928 cell Originator: Koeffler,H.P. & Golde,D,W. RCB1928 Derived from tissue: bone marrow in animal: human. LCL-1057 ATCC: CCL-246.1 A immortal human bone marrow-derived cell line cell that has the characteristics: Human cell line derived from acute myelogenous leukemia. The variant subline of KG-1(RCB1166) cell line. TKG0402(Deposited from Tohoku Univ.). RIKEN Cell bank Team Yongqun He KG-1a Register: Obinata, Masuo RCB1902 cell RIKEN Cell bank Team Yongqun He CHEMBL: CHEMBL3308109 disease: tongue cancer,squamous cell carcinoma LCL-1218 A immortal human tongue-derived cell line cell that has the characteristics: Human tongue squamous cell carcinoma derived cell line. TKG0489 (Deposited from Tohoku Univ.). Derived from tissue: tongue in animal: human. JHSF: JCRB0624 RCB1902 CVCL: CVCL_1289 HSC-4 Register: Obinata, Masuo RCB1974 cell LCL-1221 CVCL: CVCL_1675 JHSF: JCRB0260 RCB1974 RIKEN Cell bank Team Yongqun He A immortal human tongue-derived cell line cell that has the characteristics: Human cell line derived from tongue cancer. Squamous cell carcinoma. TKG0470(Deposited from Tohoku Univ.). SAS disease: tongue cancer,squamous cell carcinoma Originator: Takahashi, K. Derived from tissue: tongue in animal: human. Register: Obinata, Masuo CHEMBL: CHEMBL3308781 RCB1975 cell RCB1975 LCL-1217 A immortal human tongue-derived cell line cell that has the characteristics: Human tongue squamous cell carcinoma cell line. HLA-A 2/24. TKG0484(Deposited from Tohoku Univ.). disease: tongue cancer,squamous cell carcinoma Register: Obinata, Masuo CHEMBL: CHEMBL3307947 Originator: Momose, F. CVCL: CVCL_1288 JHSF: JCRB0623 Derived from tissue: tongue in animal: human. RIKEN Cell bank Team Yongqun He HSC-3 RCB0881 cell Sanger: COSMIC ID:909256 Originator: Sawada, Tetsuji A immortal human mammary gland-derived cell line cell that has the characteristics: Same as OCUB-1, OCUB-F. Chromosome = pseudotetraploid. Derived from tissue: mammary gland, pleural fluid in animal: human. CVCL: CVCL_1621 CHEMBL: CHEMBL3308245 OCUB-M RIKEN Cell bank Team Yongqun He RCB0881 Register: Sawada, Tetsuji ZN LCL-1489 cell cell type cell A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CALOHA:TS-2035 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000324 FMA:68646 GO:0005623 KUPO:0000002 The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). VHOG:0001533 WBbt:0004017 XAO:0003012 cell PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. "...Epithelial cells were harvested from histologically confirmed adenocarcinomas .." cell primary cultured cell A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. primary cultured cell native cell A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). CARO:0000013 To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12). cell cell in vivo cultured cell A cell in vitro that is or has been maintained or propagated as part of a cell culture. Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. cell cultured cell neuroblast BTO:0000930 FBbt:00005146 FMA:70563 cell A cell that will develop into a neuron often after a migration phase. stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. CALOHA:TS-2086 FMA:63368 cell neuronal stem cell BTO:0002881 CALOHA:TS-2360 FMA:86684 NSC Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. cell neural stem cell multi fate stem cell A stem cell that can give rise to multiple lineages of cells. FMA:84789 cell multi-fate stem cell multifate stem cell multipotent cell multipotent stem cell non-terminally differentiated cell A precursor cell with a limited number of potential fates. BTO:0000125 FMA:84782 blast cell cell define using PATO mulit-potent or oligopotent? fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. BTO:0000452 BTO:0000452 CALOHA:TS-0362 CL:0000057 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496 FMA:63877 James Malone NIFSTD:nlx_cell_20090201 These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#fibroblast VHOG:0001482 cell mouse embryonic fibroblast primary dermal fibroblast epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. BTO:0000414 BTO:0000414 CALOHA:TS-2026 CARO:0000077 CL:0000066 Cell that cover the surface of the body and line its cavities. Cell that line the inner and outer surfaces of the body by forming cellular layers (epithelium) or masses (MSH). EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000475 FBbt:00000124 FMA:66768 James Malone NIFSTD:sao441624014 Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#epithelial_cell WBbt:0003672 cell epithelial epitheliocyte blood cell A cell found predominately in the blood. FMA:62844 cell T cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. BTO:0000782 CALOHA:TS-1001 CL:0000084 CL:0000804 CL:0000812 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000208 FMA:62870 James Malone T lymphocyte T lymphocyte T-cell T-lymphocyte Th1 Th2 URI: http://www.ebi.ac.uk/cellline#T_cell VHOG:0001479 cell immature T cell immature T cell mature T cell mature T cell pancreatic T effector cell bipolar neuron A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. FMA:67282 cell peripheral neuron A neuron that is part of nerve found outside the central nervous system. FMA:84664 cell contractile cell A cell whose primary function is to shorten. cell muscle cell A mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. BTO:0000888 BTO:0000902 CALOHA:TS-2032 CL:0000187 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000609 FBbt:00005074 FMA:67328 James Malone Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (muscle fibers), cardiac (myocytes, cardiac), and smooth (myocytes, smooth muscle). They are derived from embryonic (precursor) muscle cells called myoblasts (MSH). NIFSTD:sao519252327 Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#muscle_cell WBbt:0003675 cell muscle fiber myocyte myocyte electrically active cell A cell whose function is determined by the generation or the reception of an electric signal. cell motile cell A cell that moves by its own activities. cell B cell A lymphocyte of B lineage with the phenotype CD19-positive and surface immunoglobulin-positive. A lymphocyte of B lineage with the phenotype CD19-positive, CD20-positive, and capable of B cell mediated immunity. B Cells B Lymphocytes B lymphocyte B-Lymphocyte B-cell B-lymphocyte BTO:0000776 Bursa-Dependent Lymphocytes Bursa-Equivalent Lymphocyte CALOHA:TS-0068 CL:0000236 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000101 FMA:62869 Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins. James Malone NCIt:C12474 VHOG:0001480 cell eukaryotic cell cell electrically responsive cell A cell whose function is determined by its response to an electric signal. cell neuron BTO:0000938 CALOHA:TS-0683 FBbt:00005106 FMA:54527 The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. VHOG:0001483 WBbt:0003679 cell nerve cell lymphocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. BTO:0000775 CALOHA:TS-0583 Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) FMA:62863 VHOG:0001535 cell animal cell cell monocyte BTO:0000876 CALOHA:TS-0638 FMA:62864 Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. cell experimentally modified cell in vitro A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12 cell experimentally modified cell in vitro somatic stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. CALOHA:TS-2086 FMA:63368 cell leukocyte An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. BTO:0000751 CALOHA:TS-0549 FMA:62852 cell immune cell leucocyte white blood cell myeloid cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. BTO:0001441 CALOHA:TS-0647 cell myeloid leukocyte A cell of the monocyte, granulocyte, or mast cell lineage. cell myeloblast BTO:0000187 FMA:83524 The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. cell myeloid lineage restricted progenitor cell A progenitor cell restricted to the myeloid lineage. BTO:0004730 CALOHA:TS-2099 FMA:70339 Note that this is a class of cell types, not an identified single cell type. cell myeloid progenitor cell hematopoietic cell A cell of a hematopoietic lineage. BTO:0000574 CALOHA:TS-2017 FMA:70366 FMA:83598 cell haematopoietic cell haemopoietic cell hemopoietic cell cell in vitro 'In vitro', translating literally to 'in glass', typically refers to a controlled, often sterile, laboratory setting where cells or other specimens are placed by some agent for the purpose of studying or manipulating them as part of some research investigation. 'In vitro' is intended to contrast with 'native',which refers to cells or other biological entities that are found in a natural setting. It describes unicellular organisms removed from a natural environement and multicellular organism cells removed from an organism, or cells derived in culture from such displaced cells. 2012-01-12T09:58:38Z A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. cell haendel hematopoietic lineage restricted progenitor cell 2010-01-06T03:43:20Z A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. cell tmeehan nongranular leukocyte 2010-07-22T11:30:33Z A leukocyte that lacks granules. FMA:62855 agranular leukocyte cell tmeehan nucleate cell 2010-09-07T03:32:33Z A cell containing at least one nucleus. FMA:67513 cell tmeehan neural cell 2010-09-15T01:34:57Z A cell that is part of the nervous system. CALOHA:TS-2040 FMA:70333 cell tmeehan connective tissue cell 2010-09-15T03:01:54Z A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. CALOHA:TS-2096 CL:1000406 FMA:63875 cell tmeehan somatic cell 2010-09-24T09:44:42Z A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). BTO:0001268 FMA:72300 WBbt:0008378 cell tmeehan hematopoietic precursor cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. precursor cell A cell that, by division or terminal differentiation, can give rise to other cell types. Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. simple genetic disease "A hereditary disease that is the result of one or more abnormal alleles and may be dominant (a single copy of the abnormal allele is sufficient to give rise to the disease), semi-dominant, or recessive (requiring both copies of the gene to have an abnormal allele)." [DO:wk\,ls] URI: http://www.ebi.ac.uk/cellline#simple_genetic_disease Askin's tumor Askin tumor DOID:0050608 disease_ontology reproductive organ benign neoplasm An organ system benign neoplasm that is located_in reproductive system organs. DOID:0050622 disease_ontology organ system cancer 2011-06-13T03:28:33Z A cancer that is classified based on the organ it starts in. DOID:0050686 disease_ontology snadendla cell type cancer 2011-06-13T03:28:50Z A cancer that is classified by the type of cell from which it is derived. DOID:0050687 disease_ontology snadendla lymphoplasmacytic lymphoma 2012-09-18T02:00:45Z A B-cell lymphocytic neoplasm characterized by an uncontrolled increase of B-cells. DOID:0050747 ICD10CM:C88.0 ICD9CM:273.3 MSH:D008258 NCI:C80307 OMIM:153600 OMIM:610430 ORDO:33226 SNOMEDCT_US_2015_03_01:109981009 SNOMEDCT_US_2015_03_01:154750002 SNOMEDCT_US_2015_03_01:190014001 SNOMEDCT_US_2015_03_01:190817009 SNOMEDCT_US_2015_03_01:190818004 SNOMEDCT_US_2015_03_01:190821002 SNOMEDCT_US_2015_03_01:267503004 SNOMEDCT_US_2015_03_01:35562000 UMLS_CUI:C0024419 UMLS_CUI:C2936755 Waldenström's macroglobulinemia Xref MGI. disease_ontology lschriml lymphoma A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs. DOID:0060058 DOID:1033 DOID:353 ICD10CM:C85.9 MSH:D008223 NCI:C3208 NCI:C7065 SNOMEDCT_US_2015_03_01:115244002 SNOMEDCT_US_2015_03_01:118600007 SNOMEDCT_US_2015_03_01:134218000 SNOMEDCT_US_2015_03_01:188676008 SNOMEDCT_US_2015_03_01:188694002 SNOMEDCT_US_2015_03_01:188695001 SNOMEDCT_US_2015_03_01:188704004 SNOMEDCT_US_2015_03_01:189959002 SNOMEDCT_US_2015_03_01:189965002 SNOMEDCT_US_2015_03_01:21964009 SNOMEDCT_US_2015_03_01:269627002 SNOMEDCT_US_2015_03_01:414628006 UMLS_CUI:C0024299 UMLS_CUI:C0598798 disease_ontology lymphoid cancer non-Hodgkin lymphoma A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma. DOID:0060060 OMIM mapping confirmed by DO. [LS]. OMIM:605027 disease_ontology cutaneous T cell lymphoma A non-Hodgkin's lymphoma that is caused by a mutation of T cells. DOID:0060061 disease_ontology benign neoplasm 2011-05-11T12:18:41Z A disease of cellular proliferation that results in abnormal growths in the body which lack the ability to metastasize. DOID:0060072 disease_ontology lschriml breast benign neoplasm 2011-06-08T01:02:29Z DOID:0060082 disease_ontology lschriml immune system cancer 2011-06-08T01:11:18Z An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system. DOID:0060083 disease_ontology lschriml organ system benign neoplasm 2011-07-14T12:12:23Z A benign neoplasm that is classified by the organ system from which it is arising from. DOID:0060085 disease_ontology lschriml male reproductive organ benign neoplasm 2011-07-14T12:20:52Z DOID:0060087 disease_ontology lschriml musculoskeletal system cancer 2011-07-15T02:30:51Z An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs. DOID:0060100 DOID:0060124 disease_ontology lschriml skeletal system cancer myeloma "A bone marrow cancer that affects plasma cells in which abnormal plasma cells multiply uncontrollably in the bone marrow and occasionally in other parts of the body." [url:http\://www.merck.com/mmhe/sec14/ch175/ch175c.html#sec14-ch175-ch175c-328] URI: http://www.ebi.ac.uk/cellline#myeloma intestinal cancer A gastrointestinal system cancer that is located_in the intestine. DOID:10155 ICD10CM:C26.0 ICD9CM:159.0 MSH:D007414 NCI:C4572 SNOMEDCT_US_2015_03_01:187819006 SNOMEDCT_US_2015_03_01:190089002 SNOMEDCT_US_2015_03_01:363508008 SNOMEDCT_US_2015_03_01:93838000 UMLS_CUI:C0346627 disease_ontology malignant intestinal tumors malignant neoplasm of intestine pelvic cancer "A cancer by anatomical entity that is manifested in the pelvic region." [url:http\://www.wrongdiagnosis.com/p/pelvic_cancer/intro.htm] "neoplasm of pelvis (disorder)" EXACT [SNOMEDCT_2005_07_31:126644004] "pelvis neoplasm" EXACT [CSP2005:2005-4862] MSH2010_2010_02_22:D010386 SNOMEDCT_2010_1_31:126644004 UMLS_CUI:C0030793 URI: http://www.ebi.ac.uk/cellline#pelvic_cancer malignant neoplasm of pelvis "malignant neoplasm of pelvis NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:188370005] "malignant neoplasm of pelvis, NOS" EXACT [SNOMEDCT_2005_07_31:93953009] "malignant tumor of pelvis (disorder)" EXACT [SNOMEDCT_2005_07_31:363484005] ICD9CM_2010:195.3 SNOMEDCT_2010_1_31:188370005 SNOMEDCT_2010_1_31:363484005 SNOMEDCT_2010_1_31:93953009 UMLS_CUI:C0153663 URI: http://www.ebi.ac.uk/cellline#malignant_neoplasm_of_pelvis prostate carcinoma A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:10286 EFO:0001663 KEGG:05215 NCI:C4863 SNOMEDCT_US_2015_03_01:154531004 SNOMEDCT_US_2015_03_01:254900004 SNOMEDCT_US_2015_03_01:363448003 UMLS_CUI:C0600139 cancer of prostate carcinoma OF PROSTATE carcinoma of prostate carcinoma of prostate (disorder) disease_ontology lymphoid cancer "A hematologic cancer that is located_in lymphocytes which is composed_of white blood cell." [url:http\://www.cancer.gov/dictionary/?CdrID=46298] "lymphoid neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414628006] "lymphoid neoplasm" EXACT [CSP2005:2004-6589] "lymphoid tumor" EXACT [NCI2004_11_17:C7065] NCI2009_04D:C7065 SNOMEDCT_2010_1_31:414628006 UMLS_CUI:C0598798 URI: http://www.ebi.ac.uk/cellline#lymphoid_cancer breast fibrocystic disease DOID:10354 Diffuse cystic mastopathy FIBROcystic DISEASE OF breast Fibrocystic disease of breast Fibrocystic disease of breast (disorder) ICD10CM:N60 ICD10CM:N60.1 ICD9CM:610.1 MSH:D005348 NCI:C3039 SNOMEDCT_US_2015_03_01:198091009 SNOMEDCT_US_2015_03_01:237436008 SNOMEDCT_US_2015_03_01:27431007 UMLS_CUI:C0016034 breast Fibrocystic Change disease_ontology lymphoblastic leukemia A leukemia that has_material_basis_in lymphoblasts (immature white blood cells). DOID:1037 ICD10CM:C91 ICD10CM:C91.9 ICD10CM:C91.90 ICD9CM:204 ICD9CM:204.9 ICD9CM_2010:204 ICD9CM_2010:204.9 MSH2010_2010_02_22:D007945 MSH:D007945 NCI2009_04D:C7539 NCI:C7539 SNOMEDCT_2010_1_31:154587007 SNOMEDCT_2010_1_31:188725004 SNOMEDCT_2010_1_31:188731001 SNOMEDCT_2010_1_31:190033006 SNOMEDCT_2010_1_31:269631008 SNOMEDCT_2010_1_31:32280000 SNOMEDCT_2010_1_31:93170002 SNOMEDCT_US_2015_03_01:154587007 SNOMEDCT_US_2015_03_01:188725004 SNOMEDCT_US_2015_03_01:188731001 SNOMEDCT_US_2015_03_01:190033006 SNOMEDCT_US_2015_03_01:269631008 SNOMEDCT_US_2015_03_01:32280000 SNOMEDCT_US_2015_03_01:93170002 UMLS_CUI:C0023448 UMLS_CUI:C0023448 URI: http://www.ebi.ac.uk/cellline#lymphoblastic_leukemia disease_ontology chronic lymphocytic leukemia A lymphoblastic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood. B-cell chronic lymphocytic leukemia B-cell chronic lymphoid leukemia CLL DOID:1040 EFO:0000095 ICD10CM:C91.1 ICD10CM:C91.10 ICD9CM:204.1 MSH:D015451 NCI:C3162 NCI:C3163 OMIM:109543 OMIM:151400 OMIM:609630 OMIM:612557 OMIM:612558 OMIM:612559 ORDO:67038 SNOMEDCT_US_2015_03_01:154589005 SNOMEDCT_US_2015_03_01:277473004 SNOMEDCT_US_2015_03_01:51092000 SNOMEDCT_US_2015_03_01:92814006 UMLS_CUI:C0023434 Xref MGI. chronic lymphatic leukemia disease_ontology lymphoplasmacytic leukemia stomach cancer A gastrointestinal system cancer that is located_in the stomach. Ca body - stomach Ca lesser curvature - stomach (disorder) DOID:10534 DOID:10539 DOID:10542 DOID:10543 DOID:4713 ICD10CM:C16 ICD10CM:C16.2 ICD10CM:C16.5 ICD10CM:C16.6 ICD10CM:C16.9 ICD9CM:151 ICD9CM:151.4 ICD9CM:151.5 ICD9CM:151.6 ICD9CM:151.9 MSH:D013274 NCI:C3387 NCI:C9331 OMIM mapping confirmed by DO. [SN]. OMIM:137215 OMIM:613659 SNOMEDCT_US_2015_03_01:126824007 SNOMEDCT_US_2015_03_01:154450001 SNOMEDCT_US_2015_03_01:154451002 SNOMEDCT_US_2015_03_01:154452009 SNOMEDCT_US_2015_03_01:154453004 SNOMEDCT_US_2015_03_01:187731004 SNOMEDCT_US_2015_03_01:187742008 SNOMEDCT_US_2015_03_01:187743003 SNOMEDCT_US_2015_03_01:187744009 SNOMEDCT_US_2015_03_01:187750004 SNOMEDCT_US_2015_03_01:255080008 SNOMEDCT_US_2015_03_01:269458007 SNOMEDCT_US_2015_03_01:269459004 SNOMEDCT_US_2015_03_01:269460009 SNOMEDCT_US_2015_03_01:269529007 SNOMEDCT_US_2015_03_01:269530002 SNOMEDCT_US_2015_03_01:269531003 SNOMEDCT_US_2015_03_01:269532005 SNOMEDCT_US_2015_03_01:363349007 SNOMEDCT_US_2015_03_01:93717002 SNOMEDCT_US_2015_03_01:93818001 SNOMEDCT_US_2015_03_01:93867004 SNOMEDCT_US_2015_03_01:94074003 UMLS_CUI:C0024623 UMLS_CUI:C0038356 UMLS_CUI:C0153421 UMLS_CUI:C0153422 UMLS_CUI:C0153423 ca greater curvature of stomach disease_ontology gastric neoplasm malignant neoplasm of body of stomach malignant neoplasm of lesser curve of stomach unspecified (disorder) malignant tumor of body of stomach (disorder) malignant tumor of greater curve of stomach (disorder) malignant tumor of lesser curve of stomach (disorder) gastric lymphoma DOID:10540 Lymphoma of the stomach MSH:C535648 NCI:C4636 SNOMEDCT_US_2015_03_01:276811008 UMLS_CUI:C0349532 disease_ontology gastric lymphoma (disorder) lymphoid leukemia DOID:10747 ICD9CM:204.2 SNOMEDCT_US_2015_03_01:154590001 SNOMEDCT_US_2015_03_01:188726003 SNOMEDCT_US_2015_03_01:190035004 SNOMEDCT_US_2015_03_01:33560006 SNOMEDCT_US_2015_03_01:95274002 UMLS_CUI:C0152271 disease_ontology subacute lymphoid leukemia duodenum adenocarcinoma A duodenum cancer that derives_from epithelial cells of glandular origin. DOID:10816 Duodenal adenocarcinoma NCI:C7889 SNOMEDCT_US_2015_03_01:408644002 UMLS_CUI:C0278804 adenocarcinoma of duodenum adenocarcinoma of duodenum (disorder) disease_ontology urinary bladder cancer An urinary system cancer that results_in malignant growth located_in the urinary bladder. DOID:11054 DOID:5428 ICD10CM:C67 ICD10CM:C67.9 ICD9CM:188 ICD9CM:188.9 KEGG:05219 MSH:D001749 NCI:C2901 NCI:C9334 OMIM mapping confirmed by DO. [SN]. OMIM:109800 SNOMEDCT_US_2015_03_01:126885006 SNOMEDCT_US_2015_03_01:154540000 SNOMEDCT_US_2015_03_01:188248005 SNOMEDCT_US_2015_03_01:269607003 SNOMEDCT_US_2015_03_01:363455001 SNOMEDCT_US_2015_03_01:399326009 SNOMEDCT_US_2015_03_01:93689003 UMLS_CUI:C0005684 UMLS_CUI:C0005695 bladder cancer disease_ontology tumor of the bladder esophageal carcinoma A esophageal cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:1107 EFO:0002916 NCI:C3513 SNOMEDCT_US_2015_03_01:154441003 SNOMEDCT_US_2015_03_01:255079005 SNOMEDCT_US_2015_03_01:372138000 SNOMEDCT_US_2015_03_01:93785002 UMLS_CUI:C0152018 cancer of esophagus cancer of oesophagus carcinoma OF ESOPHAGUS carcinoma of esophagus (disorder) carcinoma of oesophagus disease_ontology peripheral nervous system neoplasm "neoplasm of peripheral nerve (disorder)" EXACT [SNOMEDCT_2005_07_31:126980002] "tumor of PNS" EXACT [NCI2004_11_17:C3321] MSH2010_2010_02_22:D010524 NCI2009_04D:C3321 SNOMEDCT_2010_1_31:126980002 UMLS_CUI:C0031118 URI: http://www.ebi.ac.uk/cellline#peripheral_nervous_system_neoplasm female genital cancer female reproductive organ cancer "A cancer of reproductive system that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva." [url:http\://en.wikipedia.org/wiki/Template\:Female_genital_neoplasia, url:http\://www.wrongdiagnosis.com/g/genital_system_cancer/intro.htm] A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva. DOID:120 DOID:1244 DOID:1281 ICD10CM:C57 ICD9CM:184 MSH2010_2010_02_22:D005833 MSH:D005833 NCI2009_04D:C3053 NCI:C3053 NCI:C4913 SNOMEDCT_2010_1_31:126907002 SNOMEDCT_US_2015_03_01:126907002 SNOMEDCT_US_2015_03_01:188207007 UMLS_CUI:C0017416 UMLS_CUI:C0017416 UMLS_CUI:C0153585 UMLS_CUI:C0699889 URI: http://www.ebi.ac.uk/cellline#female_genital_cancer disease_ontology female reproductive cancer malignant Gynecologic tumor malignant neoplasm of female genital organ leukemia A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells. DOID:1240 DOID:9145 ICD10CM:C95 ICD10CM:C95.9 ICD10CM:C95.90 ICD9CM:208 ICD9CM:208.9 MSH:D007938 NCI:C3161 SNOMEDCT_US_2015_03_01:154598008 SNOMEDCT_US_2015_03_01:188762002 SNOMEDCT_US_2015_03_01:188767008 SNOMEDCT_US_2015_03_01:190024009 SNOMEDCT_US_2015_03_01:190025005 SNOMEDCT_US_2015_03_01:190029004 SNOMEDCT_US_2015_03_01:190071003 SNOMEDCT_US_2015_03_01:255049003 SNOMEDCT_US_2015_03_01:87163000 SNOMEDCT_US_2015_03_01:93143009 UMLS_CUI:C0023418 disease_ontology blood coagulation disorder "postpartum coagulation defect with delivery" EXACT [] "postpartum coagulation defect" EXACT [] ICD9CM_2010:286 MSH2010_2010_02_22:D001778 NCI2009_04D:C2902 OMIM2009_05_01:MTHU008649 SNOMEDCT_2010_1_31:127073005 SNOMEDCT_2010_1_31:154815003 SNOMEDCT_2010_1_31:191303002 SNOMEDCT_2010_1_31:267562007 SNOMEDCT_2010_1_31:362970003 SNOMEDCT_2010_1_31:64779008 UMLS_CUI:C0005779 URI: http://www.ebi.ac.uk/cellline#blood_coagulation_disorder acute leukemia A leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia [ALL]) or myeloid cells (acute myelocytic leukemia [AML]) proliferate abnormally, replacing normal marrow tissue and hematopoietic cells and inducing anemia, thrombocytopenia, and granulocytopenia. DOID:12603 DOID:12621 ICD10CM:C95.0 ICD10CM:C95.00 ICD9CM:208.0 NCI2009_04D:C9298 NCI:C9300 OMIM:308960 SNOMEDCT_US_2015_03_01:154599000 SNOMEDCT_US_2015_03_01:188763007 SNOMEDCT_US_2015_03_01:24072005 SNOMEDCT_US_2015_03_01:91855006 Stem cell Leukemia Stem cell leukaemia UMLS_CUI:C0085669 UMLS_CUI:C1378511 disease_ontology malignant neoplasm of genitourinary organ ICD9CM_2010:187 SNOMEDCT_2010_1_31:188229006 SNOMEDCT_2010_1_31:188238008 UMLS_CUI:C0153597 URI: http://www.ebi.ac.uk/cellline#malignant_neoplasm_of_genitourinary_organ vulva carcinoma A vulva cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:1294 NCI:C4866 UMLS_CUI:C0677055 Vulvar carcinoma carcinoma of vulva disease_ontology malignant neoplasm of central nervous system "malignant neoplasm of central nervous system (disorder)" EXACT [SNOMEDCT_2005_07_31:372062007] "malignant neoplasm of central nervous system NOS" EXACT [MTHICD9_2006:192.9] "malignant neoplasm of central nervous system, NOS" EXACT [SNOMEDCT_2005_07_31:93744007] "malignant neoplasm of central nervous system, unspecified (disorder)" EXACT [SNOMEDCT_2005_07_31:190135002] "malignant tumor of CNS" EXACT [NCI2004_11_17:C4627] NCI2009_04D:C4627 SNOMEDCT_2010_1_31:190135002 SNOMEDCT_2010_1_31:372062007 SNOMEDCT_2010_1_31:93744007 UMLS_CUI:C0348374 URI: http://www.ebi.ac.uk/cellline#malignant_neoplasm_of_central_nervous_system brain neoplasm "BT - Brain tumour" EXACT [SNOMEDCT_2005_07_31:254935002] "brain neoplasm" EXACT [CSP2005:2006-2736] "neoplasm of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:126952004] "neoplasm of unspecified nature of brain (disorder)" EXACT [SNOMEDCT_2005_07_31:189537005] "neoplasm of unspecified nature of brain" EXACT [ICD9CM_2006:239.6] "tumor of the Brain" EXACT [NCI2004_11_17:C2907] ICD9CM_2010:239.6 MSH2010_2010_02_22:D001932 NCI2009_04D:C2907 OMIM2009_05_01:MTHU017414 SNOMEDCT_2010_1_31:126952004 SNOMEDCT_2010_1_31:189537005 SNOMEDCT_2010_1_31:254935002 UMLS_CUI:C0006118 URI: http://www.ebi.ac.uk/cellline#brain_neoplasm lung cancer A respiratory system cancer that is located_in the lung. DOID:13075 DOID:1322 DOID:1324 DOID:9881 ICD10CM:C34.1 ICD10CM:C34.2 ICD10CM:C34.3 ICD9CM:162.3 ICD9CM:162.4 ICD9CM:162.5 ICD9CM:162.8 OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210 SNOMEDCT_US_2015_03_01:187860004 SNOMEDCT_US_2015_03_01:187863002 SNOMEDCT_US_2015_03_01:187864008 SNOMEDCT_US_2015_03_01:187867001 SNOMEDCT_US_2015_03_01:187868006 SNOMEDCT_US_2015_03_01:187871003 SNOMEDCT_US_2015_03_01:187874006 SNOMEDCT_US_2015_03_01:269464000 UMLS_CUI:C0024624 UMLS_CUI:C0153491 UMLS_CUI:C0153492 UMLS_CUI:C0153493 disease_ontology lung neoplasm endometrial cancer A uterine cancer that is located_in tissues lining the uterus. DOID:1380 DOID:5654 EFO:0004230 ICD10CM:C54.1 KEGG:05213 MSH:D016889 NCI:C27815 NCI:C3012 SNOMEDCT_US_2015_03_01:123844007 UMLS_CUI:C0007103 UMLS_CUI:C0014170 disease_ontology endometrial Ca endometrial neoplasm malignant endometrial neoplasm malignant neoplasm of endometrium neoplasm of endometrium (disorder) primary malignant neoplasm of endometrium tumor of Endometrium disease of cellular proliferation "A disease of biological process that is characterized by abnormally rapid cell division." [url:http\://en.wikipedia.org/w/index.php?title=Cell_proliferation] "cell process disease" EXACT [] A disease that is characterized by abnormally rapid cell division. DOID:0000818 DOID:14566 URI: http://www.ebi.ac.uk/cellline#disease_of_cellular_proliferation cell process disease disease_ontology colon carcinoma A colon cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. Colonic carcinoma DOID:1520 NCI:C4910 OMIM mapping confirmed by DO. [SN]. OMIM:114500 SNOMEDCT_US_2015_03_01:154454005 SNOMEDCT_US_2015_03_01:269533000 UMLS_CUI:C0699790 carcinoma OF colon carcinoma of colon carcinoma of colon (disorder) disease_ontology glandular and epithelial neoplasm MSH2010_2010_02_22:D009375 UMLS_CUI:C0027660 URI: http://www.ebi.ac.uk/cellline#glandular_and_epithelial_neoplasm epithelial carcinoma "A carcinoma that derives_from the cells that line an organ." [url:http\://www.cancer.gov/dictionary/?CdrID=46422] "Unspecified epithelial neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:189559007] "epithelial neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:118285006] "epithelial neoplasm NOS (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:189546004] "epithelial neoplasm" RELATED [] "epithelial neoplasm, NOS" EXACT [NCI2004_11_17:C3709] "epithelial skin tumor" EXACT [] "epithelial tumor (qualifier value)" EXACT [SNOMEDCT_2005_07_31:134207000] "skin Epithelium tumor" EXACT [NCI2004_11_17:C7342] "tumor of surface epithelium (disorder)" EXACT [SNOMEDCT_2005_07_31:254649008] NCI2009_04D:C7342 SNOMEDCT_2010_1_31:254649008 UMLS_CUI:C0205853 UMLS_CUI:C0345976 URI: http://www.ebi.ac.uk/cellline#epithelial_carcinoma integumentary system disease URI: http://www.ebi.ac.uk/cellline#integumentary_system_disease breast cancer mammary cancer "A cancer of reproductive system that originates in the mammary gland." [url:http\://en.wikipedia.org/wiki/Mammary_tumor] "breast neoplasm" EXACT [MTH:120] "breast tumor" EXACT [NCI2004_11_17:C2910] "mammary neoplasm" RELATED [] "mammary tumor" EXACT [CSP2005:2016-0671] "neoplasm of breast (disorder)" EXACT [SNOMEDCT_2005_07_31:126926005] A thoracic cancer that originates in the mammary gland. DOID:1612 DOID:1648 DOID:4241 ICD10CM:C50 ICD9CM:174.8 MSH2010_2010_02_22:D001943 MSH:D001943 NCI2009_04D:C2910 NCI:C2910 NCI:C9335 OMIM:114480 OMIM:600048 OMIM:605365 SNOMEDCT_2010_1_31:126926005 SNOMEDCT_US_2015_03_01:126926005 SNOMEDCT_US_2015_03_01:154521006 SNOMEDCT_US_2015_03_01:190121004 SNOMEDCT_US_2015_03_01:254837009 SNOMEDCT_US_2015_03_01:269595005 UMLS_CUI:C0006142 UMLS_CUI:C0153555 UMLS_CUI:C1458155 UMLS_CUI:C1458155 URI: http://www.ebi.ac.uk/cellline#mammary_cancer breast tumor disease_ontology malignant neoplasm of breast malignant tumor of the breast mammary cancer mammary neoplasm mammary tumor primary breast cancer cancer "A neoplastic disease that is malignant and characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." [stedman:rlc, url:http\://en.wikipedia.org/wiki/cancer, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cancer] A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis. DOID:162 ICD10CM:C80 ICD10CM:C80.1 ICD9CM:199 ICD9CM_2010:239.4 MSH:D009369 NCI:C9305 SNOMEDCT_2010_1_31:189535002 SNOMEDCT_US_2015_03_01:154432008 SNOMEDCT_US_2015_03_01:154433003 SNOMEDCT_US_2015_03_01:154577008 SNOMEDCT_US_2015_03_01:187597000 SNOMEDCT_US_2015_03_01:188475001 SNOMEDCT_US_2015_03_01:188482002 SNOMEDCT_US_2015_03_01:190150006 SNOMEDCT_US_2015_03_01:269513004 SNOMEDCT_US_2015_03_01:269623003 SNOMEDCT_US_2015_03_01:269626006 SNOMEDCT_US_2015_03_01:269634000 SNOMEDCT_US_2015_03_01:363346000 SNOMEDCT_US_2015_03_01:38807002 UMLS_CUI:C0006826 UMLS_CUI:C0027639 URI: http://www.ebi.ac.uk/cellline#cancer Updating out dated UMLS CUI. disease_ontology malignant neoplasm malignant tumor primary cancer embryonal cancer of CNS "An embryonal cancer that are masses of rapidly growing cells that originates in embryonic (fetal) tissue in the brain and spinal cord." [url:http\://www.cancer.gov/cancertopics/childCNSembryonal] "embryonal neoplasm of CNS" RELATED [] "embryonal tumor of the CNS" EXACT [NCI2004_11_17:C6990] NCI2009_04D:C6990 UMLS_CUI:C1333378 URI: http://www.ebi.ac.uk/cellline#embryonal_cancer_of_CNS primitive neuroectodermal tumor "CNS PNET" EXACT [NCI2004_11_17:C5398] "CPNET" EXACT [SNOMEDCT_2005_07_31:39781001] "primitive neuroectodermal tumour" EXACT [SNOMEDCT_2005_07_31:189925001] MSH2010_2010_02_22:D018242 NCI2009_04D:C5398 SNOMEDCT_2010_1_31:189925001 SNOMEDCT_2010_1_31:39781001 UMLS_CUI:C0206663 URI: http://www.ebi.ac.uk/cellline#primitive_neuroectodermal_tumor musculoskeletal system disease "Musculo-skeletal disorder NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:274149006] "Musculo-skeletal disorder NOS" EXACT [SNOMEDCT_2005_07_31:156881000] "Musculo-skeletal disorder NOS" EXACT [SNOMEDCT_2005_07_31:268142006] "Musculoskeletal disease" EXACT [MTH:NOCODE] "Musuloskeletal disease" EXACT [SNOMEDCT_2005_07_31:268047003] "disorder of musculoskeletal system (disorder)" EXACT [SNOMEDCT_2005_07_31:928000] "musculoskeletal disorder" EXACT [CSP2005:4000-0257] MSH2010_2010_02_22:D009140 SNOMEDCT_2010_1_31:156881000 SNOMEDCT_2010_1_31:268047003 SNOMEDCT_2010_1_31:268142006 SNOMEDCT_2010_1_31:274149006 SNOMEDCT_2010_1_31:928000 UMLS_CUI:C0026857 URI: http://www.ebi.ac.uk/cellline#musculoskeletal_system_disease endocrine gland cancer "A cancer by anatomical entity that affects any gland in the endocrine system." [url:http\://www.wrongdiagnosis.com/e/endocrine_system_cancer/basics.htm] "Endocrine tumor" EXACT [NCI2004_11_17:C3010] "endocrine neoplasm" EXACT [CSP2005:2009-5861] "neoplasm of endocrine gland (disorder)" EXACT [SNOMEDCT_2005_07_31:127015005] "neoplasm of endocrine gland (disorder)" EXACT [SNOMEDCT_2005_07_31:387922007] "neoplasm of endocrine system (disorder)" EXACT [SNOMEDCT_2005_07_31:387927001] An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system. DOID:10009 DOID:170 Endocrine tumor ICD10CM:C75.9 ICD9CM:194.9 MSH2010_2010_02_22:D004701 MSH:D004701 NCI2009_04D:C3010 NCI:C3010 NCI:C3575 SNOMEDCT_2010_1_31:127015005 SNOMEDCT_2010_1_31:387922007 SNOMEDCT_2010_1_31:387927001 SNOMEDCT_US_2015_03_01:127015005 SNOMEDCT_US_2015_03_01:190140005 SNOMEDCT_US_2015_03_01:363347009 SNOMEDCT_US_2015_03_01:371982006 SNOMEDCT_US_2015_03_01:387922007 SNOMEDCT_US_2015_03_01:387927001 SNOMEDCT_US_2015_03_01:93780007 UMLS_CUI:C0014132 UMLS_CUI:C0014132 UMLS_CUI:C0153658 URI: http://www.ebi.ac.uk/cellline#endocrine_gland_cancer disease_ontology endocrine neoplasm malignant Endocrine tumor malignant neoplasm of endocrine gland malignant tumour of endocrine gland neoplasm of endocrine gland (disorder) neoplasm of endocrine system (disorder) neuroectodermal tumor "Neuroectodermal tumour" EXACT [SNOMEDCT_2005_07_31:253096008] "Neuroectodermal tumour" EXACT [SNOMEDCT_2005_07_31:73676002] "primitive Neuroectodermal neoplasm" EXACT [NCI2004_11_17:C3716] MSH2010_2010_02_22:D017599 NCI2009_04D:C3716 SNOMEDCT_2010_1_31:253096008 SNOMEDCT_2010_1_31:73676002 UMLS_CUI:C0206093 URI: http://www.ebi.ac.uk/cellline#neuroectodermal_tumor squamous cell carcinoma A carcinoma that derives_from squamous epithelial cells. DOID:1749 DOID:5512 EFO:0000707 MSH:D002294 MSH:D018307 NCI:C2929 SNOMEDCT_US_2015_03_01:154605007 SNOMEDCT_US_2015_03_01:189566008 SNOMEDCT_US_2015_03_01:28899001 SNOMEDCT_US_2015_03_01:402815007 UMLS_CUI:C0007137 UMLS_CUI:C0751688 disease_ontology epidermoid carcinoma malignant squamous cell tumor squamous carcinoma squamous cell Epithelioma squamous cell cancer squamous cell carcinoma (disorder) squamous cell carcinoma (morphologic abnormality) squamous cell carcinoma NOS (morphologic abnormality) soft tissue neoplasm "neoplasm of soft tissue (disorder)" EXACT [SNOMEDCT_2005_07_31:387837005] "neoplasm of soft tissues (disorder)" EXACT [SNOMEDCT_2005_07_31:126600002] "tumor of the soft tissue" EXACT [NCI2004_11_17:C3377] MSH2010_2010_02_22:D012983 NCI2009_04D:C3377 SNOMEDCT_2010_1_31:126600002 SNOMEDCT_2010_1_31:387837005 UMLS_CUI:C0037579 URI: http://www.ebi.ac.uk/cellline#soft_tissue_neoplasm thyroid cancer An endocrine gland cancer located_in the thryoid gland located in the neck below the thyroid cartilage. DOID:10008 DOID:1781 ICD10CM:C73 ICD9CM:193 KEGG:05216 MSH:D013964 NCI:C3414 NCI:C7510 SNOMEDCT_US_2015_03_01:127018007 SNOMEDCT_US_2015_03_01:154554008 SNOMEDCT_US_2015_03_01:363478007 SNOMEDCT_US_2015_03_01:94098005 Thyroid gland neoplasm UMLS_CUI:C0007115 UMLS_CUI:C0040136 disease_ontology malignant neoplasm of thyroid gland malignant tumour of thyroid gland neoplasm of thyroid gland thyroid neoplasm malignant mesothelioma A cell type cancer that has_material_basis_in mesothelial tissue. DOID:1790 DOID:4487 DOID:6965 DOID:7434 Diffuse malignant Mesothelioma MSH:C562839 NCI:C27926 NCI:C4456 NCI:C7865 NCI:C8420 OMIM mapping confirmed by DO. [SN]. OMIM:156240 SNOMEDCT_US_2015_03_01:62064005 UMLS_CUI:C0278752 UMLS_CUI:C0345967 UMLS_CUI:C0392400 UMLS_CUI:C1332338 advanced malignant mesothelioma asbestos-related malignant mesothelioma disease_ontology malignant tumor of Mesothelium pancreatic cancer An endocrine gland cancer located_in the pancreas. Ca body of pancreas Ca head of pancreas Ca tail of pancreas DOID:14356 DOID:1793 DOID:1797 DOID:3588 DOID:9859 ICD10CM:C25.0 ICD10CM:C25.1 ICD10CM:C25.2 ICD9CM:157.0 ICD9CM:157.1 ICD9CM:157.2 ICD9CM:157.8 KEGG:05212 MSH:D010190 NCI:C3305 OMIM:606856 OMIM:613347 OMIM:613348 OMIM:614320 ORDO:1333 ORDO:217074 SNOMEDCT_US_2015_03_01:126859007 SNOMEDCT_US_2015_03_01:154476001 SNOMEDCT_US_2015_03_01:154477005 SNOMEDCT_US_2015_03_01:154478000 SNOMEDCT_US_2015_03_01:187791002 SNOMEDCT_US_2015_03_01:187792009 SNOMEDCT_US_2015_03_01:187796007 SNOMEDCT_US_2015_03_01:269553001 SNOMEDCT_US_2015_03_01:269554007 SNOMEDCT_US_2015_03_01:269555008 SNOMEDCT_US_2015_03_01:363419009 SNOMEDCT_US_2015_03_01:93715005 SNOMEDCT_US_2015_03_01:93823001 SNOMEDCT_US_2015_03_01:94082003 UMLS_CUI:C0030297 UMLS_CUI:C0153458 UMLS_CUI:C0153459 UMLS_CUI:C0153460 UMLS_CUI:C0153463 Xref MGI. disease_ontology malignant neoplasm of body of pancreas malignant neoplasm of head of pancreas malignant neoplasm of tail of pancreas pancreas neoplasm pancreatic neoplasm pancreatic tumor urinary system disease URI: http://www.ebi.ac.uk/cellline#urinary_system_disease bone tissue neoplasm MSH2010_2010_02_22:D018213 UMLS_CUI:C0206639 URI: http://www.ebi.ac.uk/cellline#bone_tissue_neoplasm bone cancer A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue. CA - bone cancer CSP:2019-1041 DOID:184 DOID:3348 MSH:D001859 NCI:C9343 SNOMEDCT_US_2015_03_01:115239009 SNOMEDCT_US_2015_03_01:126537000 SNOMEDCT_US_2015_03_01:240201007 UMLS_CUI:C0005967 bone neoplasm bone tumor (morphologic abnormality) bone tumour disease_ontology malignant bone neoplasm malignant bone tumour malignant neoplasm of bone, NOS malignant osseous tumor neoplasm of bone (disorder) osseous tumor melanoma A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from melanocytes which are found in skin, the bowel and the eye. DOID:1909 EFO:0000756 KEGG:05218 MSH:D008545 NCI:C3224 Naevocarcinoma OMIM:155600 SNOMEDCT_US_2015_03_01:154501005 SNOMEDCT_US_2015_03_01:189749008 SNOMEDCT_US_2015_03_01:2092003 SNOMEDCT_US_2015_03_01:269503007 SNOMEDCT_US_2015_03_01:269577007 SNOMEDCT_US_2015_03_01:372244006 UMLS_CUI:C0025202 disease_ontology malignant melanoma cancer of reproductive system reproductive organ cancer "A cancer by anatomical entity that is manifested in the reproductive system." [url:http\://en.wikipedia.org/wiki/Reproductive_system#Examples_of_cancers] "Reproductive tumor" EXACT [NCI2004_11_17:C3674] "malignant reproductive system neoplasm" EXACT [] "reproductive system neoplasm" EXACT [CSP2005:2016-0492] An organ system cancer that is manifested in the reproductive organs. DOID:1900 DOID:193 NCI2009_04D:C3674 NCI:C3674 Reproductive tumor UMLS_CUI:C0178830 UMLS_CUI:C0178830 URI: http://www.ebi.ac.uk/cellline#cancer_of_reproductive_system cancer of reproductive system disease_ontology malignant reproductive system neoplasm glandular cell epithelial neoplasm "glandular cell Epithelium neoplasm" EXACT [NCI2004_11_17:C7132] NCI2009_04D:C7132 UMLS_CUI:C1333820 URI: http://www.ebi.ac.uk/cellline#glandular_cell_epithelial_neoplasm rectum adenocarcinoma A rectum cancer that derives_from epithelial cells of glandular origin. DOID:1996 NCI:C9383 Rectal adenocarcinoma SNOMEDCT_US_2015_03_01:254582000 UMLS_CUI:C0149978 adenocarcinoma of rectum adenocarcinoma of rectum (disorder) disease_ontology connective tissue cancer connective tissue neoplasm "Tumour of connective tissue" EXACT [SNOMEDCT_2005_07_31:254821003] "connective tissue neoplasm" EXACT [CSP2005:2008-3809] "neoplasm of connective tissues (disorder)" EXACT [SNOMEDCT_2005_07_31:126598008] A musculoskeletal system cancer that is located_in connective tissue. DOID:201 MSH2010_2010_02_22:D009372 MSH:D009372 SNOMEDCT_2010_1_31:126598008 SNOMEDCT_2010_1_31:254821003 SNOMEDCT_US_2015_03_01:126598008 SNOMEDCT_US_2015_03_01:254821003 Tumour of connective tissue UMLS_CUI:C0027656 UMLS_CUI:C0027656 URI: http://www.ebi.ac.uk/cellline#connective_tissue_neoplasm connective tissue neoplasm disease_ontology neoplasm of connective tissues vulva squamous cell carcinoma A vulva carcinoma and has_material_basis_in squamous cells and is located_in the epidermis of the vulvar tissue. DOID:2101 NCI:C4052 SNOMEDCT_US_2015_03_01:254895003 UMLS_CUI:C0280856 Vulvar Epidermoid carcinoma disease_ontology squamous cell carcinoma of vulva vulvar squamous cell carcinoma intracranial neoplasm "intracranial central nervous system tumors" EXACT [NCI2004_11_17:C4953] "intracranial tumor (disorder)" EXACT [SNOMEDCT_2005_07_31:254935002] NCI2009_04D:C4953 SNOMEDCT_2010_1_31:254935002 UMLS_CUI:C1527390 URI: http://www.ebi.ac.uk/cellline#intracranial_neoplasm hemorrhagic disorder "HEMORRHAGIC DISORDER" EXACT [MTH:NOCODE] "Haemorrhagic condition, unspecified" EXACT [SNOMEDCT_2005_07_31:191327000] "Hemorrhagic condition NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:191331006] "Hemorrhagic condition, unspecified (disorder)" EXACT [SNOMEDCT_2005_07_31:191437009] "Hemorrhagic diathesis" EXACT [MTHICD9_2006:287.9] "Hemorrhagic disease" EXACT [SNOMEDCT_2005_07_31:268884000] "Unspecified hemorrhagic conditions" EXACT [ICD9CM_2006:287.9] "hemorrhagic disorder" EXACT [CSP2005:0427-4811] ICD9CM_2010:287.9 MSH2010_2010_02_22:D006474 SNOMEDCT_2010_1_31:191327000 SNOMEDCT_2010_1_31:191331006 SNOMEDCT_2010_1_31:191437009 SNOMEDCT_2010_1_31:268884000 UMLS_CUI:C0019087 URI: http://www.ebi.ac.uk/cellline#hemorrhagic_disorder malignant neoplasm of lymphatic and hemopoietic tissue ICD9CM_2010:202.8 UMLS_CUI:C0029662 URI: http://www.ebi.ac.uk/cellline#malignant_neoplasm_of_lymphatic_and_hemopoietic_tissue female reproductive system disease ICD9CM_2010:629.9 MSH2010_2010_02_22:D005831 SNOMEDCT_2010_1_31:156032001 SNOMEDCT_2010_1_31:156066005 SNOMEDCT_2010_1_31:198486002 SNOMEDCT_2010_1_31:244938009 SNOMEDCT_2010_1_31:266680004 SNOMEDCT_2010_1_31:310789003 SNOMEDCT_2010_1_31:38233001 UMLS_CUI:C0017411 URI: http://www.ebi.ac.uk/cellline#female_reproductive_system_disease colon adenocarcinoma A colon carcinoma that derives_from epithelial cells of glandular origin. Colonic adenocarcinoma DOID:234 NCI:C4349 SNOMEDCT_US_2015_03_01:255082000 UMLS_CUI:C0338106 adenocarcinoma of colon adenocarcinoma of the colon disease_ontology disorder of plasma protein metabolism ICD9CM_2010:273.8 SNOMEDCT_2010_1_31:190822009 SNOMEDCT_2010_1_31:190825006 UMLS_CUI:C0029594 URI: http://www.ebi.ac.uk/cellline#disorder_of_plasma_protein_metabolism ovarian cancer A female reproductive organ cancer that is located_in the ovary. DOID:0060070 DOID:2144 DOID:2394 DOID:9595 ICD10CM:C56 ICD9CM:183.0 MSH:D010051 NCI:C4984 NCI:C7431 OMIM:167000 OMIM:607893 ORDO:213517 SNOMEDCT_US_2015_03_01:123843001 SNOMEDCT_US_2015_03_01:154528000 SNOMEDCT_US_2015_03_01:363443007 SNOMEDCT_US_2015_03_01:372117006 SNOMEDCT_US_2015_03_01:93934004 UMLS_CUI:C0919267 UMLS_CUI:C1140680 UMLS_CUI:C1299247 disease_ontology malignant Ovarian tumor malignant tumour of ovary ovarian neoplasm ovary neoplasm primary ovarian cancer tumor of the Ovary skin tumor of neural origin "neural tumor of the skin" EXACT [NCI2004_11_17:C4479] "skin tumor of neural origin (disorder)" EXACT [SNOMEDCT_2005_07_31:254758008] NCI2009_04D:C4479 SNOMEDCT_2010_1_31:254758008 UMLS_CUI:C0346055 URI: http://www.ebi.ac.uk/cellline#skin_tumor_of_neural_origin tumor of Dermis "neoplasm of Dermis" EXACT [NCI2004_11_17:C4475] "tumor of dermis (disorder)" EXACT [SNOMEDCT_2005_07_31:254735005] NCI2009_04D:C4475 SNOMEDCT_2010_1_31:254735005 UMLS_CUI:C0346041 URI: http://www.ebi.ac.uk/cellline#tumor_of_Dermis prostate adenocarcinoma A prostate carcinoma that derives_from epithelial cells of glandular origin. DOID:2526 NCI:C2919 SNOMEDCT_US_2015_03_01:399490008 UMLS_CUI:C0007112 disease_ontology hematologic cancer "A cancer that affects the blood or bone marrow." [url:http\://www.cancer.gov/dictionary/?CdrID=45708] "Hematologic malignancy (disorder)" EXACT [SNOMEDCT_2005_07_31:127221002] "Hematologic malignancy" EXACT [SNOMEDCT_2005_07_31:269475001] "Hematologic neoplasm (disorder)" EXACT [SNOMEDCT_2005_07_31:129154003] "Hematological tumors" EXACT [NCI2004_11_17:C27134] "blood cancer" EXACT [CSP2005:2004-0139] "hematopoietic and lymphoid system tumor" EXACT [] "hematopoietic cancer" EXACT [] "hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414388001] "hematopoietic tumors" EXACT [NCI2004_11_17:C27134] "malignant hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414644002] An immune system cancer located_in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes. DOID:1034 DOID:2531 DOID:2532 Hematologic malignancy Hematologic malignancy (disorder) Hematologic neoplasm (disorder) Hematological tumors MSH2010_2010_02_22:D019337 MSH:D019337 NCI2009_04D:C27134 NCI:C27134 SNOMEDCT_2010_1_31:414388001 SNOMEDCT_2010_1_31:414644002 SNOMEDCT_US_2015_03_01:414388001 SNOMEDCT_US_2015_03_01:414644002 UMLS_CUI:C0376544 UMLS_CUI:C0376544 URI: http://www.ebi.ac.uk/cellline#hematologic_cancer blood cancer disease_ontology hematopoietic and lymphoid system tumor hematopoietic cancer hematopoietic neoplasm (morphologic abnormality) hematopoietic tumors malignant hematopoietic neoplasm (morphologic abnormality) neuroblastic tumor NCI2009_04D:C6963 UMLS_CUI:C1334953 URI: http://www.ebi.ac.uk/cellline#neuroblastic_tumor kidney cancer kidney neoplasm "kidney neoplasm" EXACT [CSP2005:2021-1116] "neoplasm of kidney (disorder)" EXACT [SNOMEDCT_2005_07_31:126880001] "renal tumors" EXACT [NCI2004_11_17:C3150] A urinary system cancer that is located_in the kidney. DOID:11834 DOID:263 DOID:3676 ICD10CM:C64 ICD9CM:189.0 MSH2010_2010_02_22:D007680 MSH:D007680 NCI2009_04D:C3150 NCI:C3150 NCI:C7548 OMIM2009_05_01:MTHU018158 SNOMEDCT_2010_1_31:126880001 SNOMEDCT_US_2015_03_01:126880001 SNOMEDCT_US_2015_03_01:154542008 SNOMEDCT_US_2015_03_01:188249002 SNOMEDCT_US_2015_03_01:363518003 SNOMEDCT_US_2015_03_01:93849006 UMLS_CUI:C0022665 UMLS_CUI:C0022665 UMLS_CUI:C0494158 UMLS_CUI:C0740457 URI: http://www.ebi.ac.uk/cellline#kidney_neoplasm disease_ontology malignant neoplasm of kidney except pelvis malignant tumour of kidney renal cancer endometrial carcinoma A endometrial cancer that is located_in the tissue lining the uterus. DOID:2871 DOID:3000 MSH:D016889 MSH:D018269 NCI:C3769 NCI:C7558 OMIM mapping confirmed by DO. [SN]. OMIM:608089 SNOMEDCT_US_2015_03_01:154526001 SNOMEDCT_US_2015_03_01:254878006 SNOMEDCT_US_2015_03_01:269600001 SNOMEDCT_US_2015_03_01:30289006 SNOMEDCT_US_2015_03_01:93781006 UMLS_CUI:C0206687 UMLS_CUI:C0476089 carcinoma of the Endometrium disease_ontology endometrioid carcinoma endometrioid carcinoma of female Reproductive system cervix carcinoma A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:2893 MSH:D002583 NCI:C9039 OMIM mapping confirmed by DO. [SN]. OMIM:603956 SNOMEDCT_US_2015_03_01:154522004 SNOMEDCT_US_2015_03_01:154525002 SNOMEDCT_US_2015_03_01:188174005 SNOMEDCT_US_2015_03_01:269596006 SNOMEDCT_US_2015_03_01:269599004 SNOMEDCT_US_2015_03_01:285432005 SNOMEDCT_US_2015_03_01:363354003 SNOMEDCT_US_2015_03_01:93752005 UMLS_CUI:C0302592 cancer of cervix carcinoma OF CERVIX carcinoma cervix uteri carcinoma of cervix (disorder) carcinoma of the Cervix Uteri disease_ontology immunoproliferative disorder "Immunoproliferative disease - morphology" EXACT [SNOMEDCT_2005_07_31:134363002] "Immunoproliferative disease, no ICD-O subtype (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:86295000] "Immunoproliferative disorder (disorder)" EXACT [SNOMEDCT_2005_07_31:127071007] MSH2010_2010_02_22:D007160 SNOMEDCT_2010_1_31:127071007 SNOMEDCT_2010_1_31:134363002 SNOMEDCT_2010_1_31:86295000 UMLS_CUI:C0021070 URI: http://www.ebi.ac.uk/cellline#immunoproliferative_disorder paraproteinemia "Paraproteinaemia" EXACT [SNOMEDCT_2005_07_31:35601003] "Paraproteinemia (disorder)" EXACT [SNOMEDCT_2005_07_31:278501001] "Paraproteinemia NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:190816000] "Paraproteinemia" EXACT [NCI2004_11_17:C27468] "Paraproteinemia" EXACT [SNOMEDCT_2005_07_31:123061006] "paraproteinemia" EXACT [CSP2005:0449-2705] MSH2010_2010_02_22:D010265 NCI2009_04D:C27468 SNOMEDCT_2010_1_31:123061006 SNOMEDCT_2010_1_31:190816000 SNOMEDCT_2010_1_31:278501001 SNOMEDCT_2010_1_31:35601003 UMLS_CUI:C0030489 URI: http://www.ebi.ac.uk/cellline#paraproteinemia adenocarcinoma "adenocarcinoma NOS (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:189582009] "adenocarcinoma" EXACT [CSP2005:2000-0386] "adenocarcinoma" EXACT [NCI2004_11_17:C2852] "adenocarcinoma, no subtype (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:35917007] "adenocarcinomas" EXACT [SNOMEDCT_2005_07_31:189578007] MSH2010_2010_02_22:D000230 NCI2009_04D:C2852 OMIM2009_05_01:MTHU014125 SNOMEDCT_2010_1_31:189578007 SNOMEDCT_2010_1_31:189582009 SNOMEDCT_2010_1_31:35917007 SNOMEDCT_2010_1_31:443961001 UMLS_CUI:C0001418 URI: http://www.ebi.ac.uk/cellline#adenocarcinoma breast ductal carcinoma A breast carcinoma that derives_from the lining of milk ducts. DOID:3007 MSH:D044584 SNOMEDCT_US_2015_03_01:82711006 UMLS_CUI:C1176475 disease_ontology duct carcinoma, NOS cecum adenocarcinoma A cecum carcinoma that derives_from epithelial cells of glandular origin. Cecal adenocarcinoma DOID:3039 NCI:C5543 SNOMEDCT_US_2015_03_01:413446001 UMLS_CUI:C1332866 adenocarcinoma of cecum adenocarcinoma of cecum (disorder) disease_ontology carcinoma "A cancer that derives_from epithelial cells." [url:http\://en.wikipedia.org/wiki/Carcinoma] "carcinoma NOS (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:189549006] "carcinoma" EXACT [CSP2005:2000-1867] "carcinoma, no subtype (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:68453008] "epithelial carcinoma" EXACT [NCI2004_11_17:C2916] A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. CSP:2000-1867 DOID:2428 DOID:305 DOID:6570 MSH2010_2010_02_22:D002277 MSH:D002277 MSH:D009375 NCI2009_04D:C2916 NCI:C2916 NCI:C3709 SNOMEDCT_2010_1_31:154433003 SNOMEDCT_2010_1_31:189549006 SNOMEDCT_2010_1_31:269513004 SNOMEDCT_2010_1_31:68453008 SNOMEDCT_US_2015_03_01:118285006 SNOMEDCT_US_2015_03_01:134207000 SNOMEDCT_US_2015_03_01:154433003 SNOMEDCT_US_2015_03_01:188083002 SNOMEDCT_US_2015_03_01:189546004 SNOMEDCT_US_2015_03_01:189549006 SNOMEDCT_US_2015_03_01:189559007 SNOMEDCT_US_2015_03_01:269513004 SNOMEDCT_US_2015_03_01:68453008 SNOMEDCT_US_2015_03_01:71298006 UMLS_CUI:C0007097 UMLS_CUI:C0007097 UMLS_CUI:C0553707 UMLS_CUI:C1368683 URI: http://www.ebi.ac.uk/cellline#carcinoma disease_ontology epithelioma malignant Epithelioma glioblastoma multiforme An astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derived_from multiple cell types including astrocytes and oligondroctyes. DOID:3068 DOID:3075 DOID:3080 GBM GBM (Glioblastoma) MSH:D005909 NCI:C3058 NCI:C39750 NCI:C9094 SNOMEDCT_US_2015_03_01:189917003 SNOMEDCT_US_2015_03_01:269506004 SNOMEDCT_US_2015_03_01:63634009 UMLS_CUI:C0017636 UMLS_CUI:C0278878 UMLS_CUI:C1514422 adult glioblastoma multiforme disease_ontology grade IV adult Astrocytic tumor primary glioblastoma multiforme spongioblastoma multiforme astrocytoma A malignant glioma that is has_material_basis_in astocyte cells, a type of star-shaped glial cell, located_in the cerebrum. Astrocytic tumor DOID:3069 DOID:4861 MSH:D001254 NCI:C4951 NCI:C60781 NCI:C6958 SNOMEDCT_US_2015_03_01:189914005 SNOMEDCT_US_2015_03_01:38713004 UMLS_CUI:C0004114 UMLS_CUI:C0750935 astrocytoma of Cerebrum astrocytoma of brain (disorder) astrocytoma, no ICD-O subtype (morphologic abnormality) astroglioma cerebral astrocytoma disease_ontology malignant glioma "glioma, malignant" EXACT [SNOMEDCT_2005_07_31:189909006] "glioma, malignant, no ICD-O subtype" EXACT [SNOMEDCT_2005_07_31:74532006] "malignant Neuroglial tumor" EXACT [NCI2004_11_17:C4822] "malignant glioma (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:269505000] "malignant glioma - category" EXACT [SNOMEDCT_2005_07_31:416500007] A cell type cancer that has_material_basis_in glial cells and is located_in brain or located_in spine. DOID:2627 DOID:3070 Gliomas (morphologic abnormality) KEGG:05214 MSH2010_2010_02_22:D005910 MSH:D005910 NCI2009_04D:C4822 NCI:C3059 NCI:C4822 Neuroglial tumor OMIM:137800 OMIM:607248 OMIM:613028 OMIM:613029 OMIM:613030 OMIM:613031 OMIM:613032 OMIM:613033 ORDO:182067 SNOMEDCT_2010_1_31:189909006 SNOMEDCT_2010_1_31:269505000 SNOMEDCT_2010_1_31:416500007 SNOMEDCT_2010_1_31:74532006 SNOMEDCT_US_2015_03_01:115240006 SNOMEDCT_US_2015_03_01:189908003 SNOMEDCT_US_2015_03_01:189909006 SNOMEDCT_US_2015_03_01:189926000 SNOMEDCT_US_2015_03_01:269505000 SNOMEDCT_US_2015_03_01:393564001 SNOMEDCT_US_2015_03_01:416500007 SNOMEDCT_US_2015_03_01:74532006 UMLS_CUI:C0017638 UMLS_CUI:C0555198 UMLS_CUI:C0555198 URI: http://www.ebi.ac.uk/cellline#malignant_glioma disease_ontology glial cell tumor glioma glioma (morphologic abnormality) glioma NOS glioma NOS (morphologic abnormality) glioma, NOS glioma, malignant glioma, malignant, no ICD-O subtype malignant Neuroglial tumor malignant glioma (morphologic abnormality) malignant glioma - category cancer of the nervous system nervous system cancer "A cancer that affects the nervous system." [url:http\://emedicine.medscape.com/oncology] "neoplasm of nervous system (disorder)" EXACT [SNOMEDCT_2005_07_31:126950007] "nervous system neoplasm" EXACT [CSP2005:2012-5157] "tumor of the nervous system" EXACT [NCI2004_11_17:C3268] An organ system cancer located_in the nervous sytem that affects the central or peripheral nervous system. DOID:1193 DOID:3093 DOID:3195 DOID:4695 ICD9CM:192 ICD9CM:192.9 MSH2010_2010_02_22:D009380 MSH:D009380 NCI:C35562 SNOMEDCT_US_2015_03_01:188306000 UMLS_CUI:C0027665 UMLS_CUI:C0027665 UMLS_CUI:C0153643 UMLS_CUI:C1334956 URI: http://www.ebi.ac.uk/cellline#cancer_of_the_nervous_system disease_ontology malignant neoplasm of nervous system neoplasm of nervous system (disorder) nervous system neoplasm neural neoplasm neural tumor tumor of the nervous system neuroepithelial neoplasm "tumor of Neuroepithelium" EXACT [NCI2004_11_17:C3787] MSH2010_2010_02_22:D018302 NCI2009_04D:C3787 UMLS_CUI:C0206715 URI: http://www.ebi.ac.uk/cellline#neuroepithelial_neoplasm germ cell and embryonal cancer "germ cell and embryonal neoplasm" RELATED [] MSH2010_2010_02_22:D009373 UMLS_CUI:C0027658 URI: http://www.ebi.ac.uk/cellline#germ_cell_and_embryonal_cancer small cell sarcoma DOID:3098 MSH:D018228 NCI:C3746 SNOMEDCT_US_2015_03_01:73506006 UMLS_CUI:C0206652 disease_ontology kidney and Ureter tumor "renal and ureteral tumor" EXACT [NCI2004_11_17:C7514] NCI2009_04D:C7514 UMLS_CUI:C1334323 URI: http://www.ebi.ac.uk/cellline#kidney_and_Ureter_tumor gastrointestinal neoplasm gastrointestinal system cancer "GI tumor" EXACT [NCI2004_11_17:C3052] "gastrointestinal neoplasm" EXACT [CSP2005:2010-0179] "neoplasm of gastrointestinal tract" EXACT [SNOMEDCT_2005_07_31:126768004] "tumor of gastrointestinal tract (disorder)" EXACT [SNOMEDCT_2005_07_31:276806006] An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system. DOID:3119 DOID:4945 DOID:8377 GI tumor ICD10CM:C26.9 ICD9CM:239.0 MSH2010_2010_02_22:D005770 MSH:D004067 MSH:D005770 NCI2009_04D:C3052 NCI:C3052 NCI:C4890 SNOMEDCT_2010_1_31:126768004 SNOMEDCT_2010_1_31:276806006 SNOMEDCT_US_2015_03_01:126768004 SNOMEDCT_US_2015_03_01:128348002 SNOMEDCT_US_2015_03_01:128415001 SNOMEDCT_US_2015_03_01:189527000 SNOMEDCT_US_2015_03_01:276806006 SNOMEDCT_US_2015_03_01:367543008 SNOMEDCT_US_2015_03_01:428905002 SNOMEDCT_US_2015_03_01:93811007 UMLS_CUI:C0012243 UMLS_CUI:C0017185 UMLS_CUI:C0017185 UMLS_CUI:C0685938 URI: http://www.ebi.ac.uk/cellline#gastrointestinal_neoplasm digestive system cancer disease_ontology gastrointestinal tract cancer skin squamous cell carcinoma A skin carcinoma that has_material_basis_in squamous cells. DOID:3151 Epidermoid skin carcinoma NCI:C4819 SNOMEDCT_US_2015_03_01:254651007 UMLS_CUI:C0553723 disease_ontology squamous cell carcinoma of skin skin neoplasm "neoplasm of skin (disorder)" EXACT [SNOMEDCT_2005_07_31:126488004] "neoplasm of skin by site" EXACT [SNOMEDCT_2005_07_31:363230005] "skin neoplasm" EXACT [CSP2005:2020-0536] "tumor of the skin" EXACT [NCI2004_11_17:C3372] MSH2010_2010_02_22:D012878 NCI2009_04D:C3372 SNOMEDCT_2010_1_31:126488004 SNOMEDCT_2010_1_31:363230005 UMLS_CUI:C0037286 URI: http://www.ebi.ac.uk/cellline#skin_neoplasm oligodendroglioma DOID:3181 DOID:3182 MSH:D009837 NCI:C6960 UMLS_CUI:C0028945 UMLS_CUI:C1335110 disease_ontology oligodendroglial neoplasm oligodendroglial tumor neural neoplasm "neural tumor" EXACT [NCI2004_11_17:C35562] NCI2009_04D:C35562 UMLS_CUI:C1334956 URI: http://www.ebi.ac.uk/cellline#neural_neoplasm rhabdomyosarcoma A skeletal muscle cancer that arise from skeletal muscle progenitors. DOID:3247 MSH:D012208 NCI:C3359 SNOMEDCT_US_2015_03_01:134166003 SNOMEDCT_US_2015_03_01:302847003 SNOMEDCT_US_2015_03_01:30924005 UMLS_CUI:C0035412 disease_ontology central nervous system disease "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system." [url:http\://en.wikipedia.org/wiki/Central_nervous_system_disease] MSH2010_2010_02_22:D002493 NCI2009_04D:C2934 SNOMEDCT_2010_1_31:138748005 SNOMEDCT_2010_1_31:154981003 SNOMEDCT_2010_1_31:155049004 SNOMEDCT_2010_1_31:155059003 SNOMEDCT_2010_1_31:192641002 SNOMEDCT_2010_1_31:193076009 SNOMEDCT_2010_1_31:194566008 SNOMEDCT_2010_1_31:23853001 SNOMEDCT_2010_1_31:267144009 SNOMEDCT_2010_1_31:267679005 SNOMEDCT_2010_1_31:267700003 SNOMEDCT_2010_1_31:267702006 SNOMEDCT_2010_1_31:275539005 UMLS_CUI:C0007682 URI: http://www.ebi.ac.uk/cellline#central_nervous_system_disease osteosarcoma A bone cancer that is located_in bone that has_material_basis_in cells of mesenchymal origin. DOID:183 DOID:3347 MSH:D012516 MSH:D018213 NCI:C9145 OMIM mapping confirmed by DO. [SN]. OMIM:259500 Osteogenic sarcoma SNOMEDCT_US_2015_03_01:189878003 SNOMEDCT_US_2015_03_01:21708004 SNOMEDCT_US_2015_03_01:307576001 SNOMEDCT_US_2015_03_01:408387006 Skeletal sarcoma UMLS_CUI:C0029463 UMLS_CUI:C0206639 bone tissue neoplasm disease_ontology osteoid sarcoma osteogenic neoplasm "Osteogenic tumor" EXACT [NCI2004_11_17:C6603] NCI2009_04D:C6603 UMLS_CUI:C1335146 URI: http://www.ebi.ac.uk/cellline#osteogenic_neoplasm mesenchymal cell neoplasm "mesenchymal tumor" EXACT [NCI2004_11_17:C7059] NCI2009_04D:C7059 UMLS_CUI:C1334699 URI: http://www.ebi.ac.uk/cellline#mesenchymal_cell_neoplasm fibrosarcoma A connective tissue cancer that has_material_basis_in fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. DOID:156 DOID:3355 DOID:3509 Fibrocytic tumor MSH:D005354 MSH:D018218 NCI:C3043 NCI:C6605 NCI:C7075 SNOMEDCT_US_2015_03_01:443250000 SNOMEDCT_US_2015_03_01:53654007 UMLS_CUI:C0016057 UMLS_CUI:C0206643 UMLS_CUI:C1336021 disease_ontology fibrosarcoma of soft tissue fibrous tissue neoplasm bone Ewing's sarcoma A peripheral primitive neuroectodermal tumor that is located_in bone. DOID:3368 DOID:4984 DOID:6392 Ewing's sarcoma of bone (disorder) Ewing's sarcoma/bone peripheral primitive neuroectodermal tumor NCI:C35871 NCI:C4835 NCI:C6623 SNOMEDCT_US_2015_03_01:307608006 Skeletal Ewing's tumor UMLS_CUI:C0585474 UMLS_CUI:C1333481 UMLS_CUI:C1334406 bone Ewing sarcoma bone Ewing's sarcoma bone localized Ewing sarcoma bone localized Ewing's sarcoma disease_ontology localized Skeletal Ewing's sarcoma Ewing sarcoma A bone cancer that has_material_basis in neural crest cells derived_from undeveloped, undifferentiated neuroectoderm. DOID:0050607 DOID:3369 DOID:4158 DOID:4390 DOID:4391 DOID:4392 DOID:4980 Ewing's family localized tumor Ewing's sarcoma/peripheral primitive neuroectodermal tumor Ewing's tumor Ewings sarcoma Ewings sarcoma-primitive neuroectodermal tumor MSH:C563168 MSH:D012512 MSH:D018241 NCI:C27901 NCI:C27903 NCI:C4817 NCI:C7542 NCI:C7806 NCI:C9341 OMIM mapping confirmed by DO. [SN]. OMIM:612219 PNET of Thoracopulmonary Region SNOMEDCT_US_2015_03_01:128783001 SNOMEDCT_US_2015_03_01:134210007 SNOMEDCT_US_2015_03_01:253096008 SNOMEDCT_US_2015_03_01:703707001 SNOMEDCT_US_2015_03_01:73506006 SNOMEDCT_US_2015_03_01:73676002 SNOMEDCT_US_2015_03_01:76909002 UMLS_CUI:C0553580 UMLS_CUI:C0684337 UMLS_CUI:C0796547 UMLS_CUI:C0863029 UMLS_CUI:C0877849 UMLS_CUI:C1334408 disease_ontology localized Ewing sarcoma localized Ewing's sarcoma localized Ewing's sarcoma/peripheral primitive neuroectodermal tumor localized Ewing's tumor localized peripheral primitive neuroectodermal tumor peripheral primitive neuroectodermal tumor chondrosarcoma A connective tissue cancer that has_material_basis_in cells derived from transformed cells that produce cartilage. DOID:3370 DOID:3371 MSH:D002813 NCI:C2946 NCI:C7155 OMIM mapping confirmed by DO. [SN]. OMIM:215300 SNOMEDCT_US_2015_03_01:14990007 SNOMEDCT_US_2015_03_01:189886003 SNOMEDCT_US_2015_03_01:443520009 UMLS_CUI:C0008479 UMLS_CUI:C1335473 chondrosarcoma of bone disease_ontology primary chondrosarcoma of the bone liposarcoma A lipomatous cancer that arises in fat cells in deep soft tissue retroperitoneum. DOID:3382 MSH:D008080 NCI:C3194 SNOMEDCT_US_2015_03_01:189777004 SNOMEDCT_US_2015_03_01:254829001 SNOMEDCT_US_2015_03_01:49430005 UMLS_CUI:C0023827 disease_ontology disease of biological process "A disease that involves any biological process (GO:0008150) specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms." [DO:wk\,ls] URI: http://www.ebi.ac.uk/cellline#disease_of_biological_process breast adenocarcinoma A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast. DOID:3458 Mammary adenocarcinoma NCI:C5214 UMLS_CUI:C0858252 adenocarcinoma of breast disease_ontology breast carcinoma A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:3459 EFO:0000305 Mammary carcinoma NCI:C4872 SNOMEDCT_US_2015_03_01:154513000 SNOMEDCT_US_2015_03_01:254838004 SNOMEDCT_US_2015_03_01:286898006 UMLS_CUI:C0678222 carcinoma OF breast carcinoma of breast carcinoma of breast (disorder) carcinoma of breast NOS (disorder) disease_ontology adult fibrosarcoma DOID:3516 NCI:C7809 UMLS_CUI:C0278595 disease_ontology liver cancer A gastrointestinal system cancer that is located_in the liver. Ca liver - primary (disorder) DOID:12300 DOID:269 DOID:3571 DOID:7330 DOID:915 DOID:919 ICD10CM:C22.0 ICD10CM:C22.9 ICD9CM:155.0 ICD9CM:155.2 MSH:D008113 NCI:C34803 NCI:C7692 Resectable malignant neoplasm of Liver SNOMEDCT_US_2015_03_01:126851005 SNOMEDCT_US_2015_03_01:154470007 SNOMEDCT_US_2015_03_01:187768001 SNOMEDCT_US_2015_03_01:187771009 SNOMEDCT_US_2015_03_01:187779006 SNOMEDCT_US_2015_03_01:269548006 SNOMEDCT_US_2015_03_01:363361004 SNOMEDCT_US_2015_03_01:93870000 SNOMEDCT_US_2015_03_01:95214007 UMLS_CUI:C0023903 UMLS_CUI:C0024620 UMLS_CUI:C0345904 UMLS_CUI:C0854795 ca liver - primary disease_ontology hepatic cancer hepatic neoplasm malignant hepato-biliary neoplasm malignant neoplasm of liver malignant neoplasm of liver (disorder) malignant neoplasm of liver unspecified (disorder) malignant neoplasm of liver, not specified as primary or secondary malignant neoplasm of liver, primary malignant tumor of liver (disorder) neoplasm of liver (disorder) non-resectable primary hepatic malignant neoplasm primary liver cancer primary malignant neoplasm of Liver primary malignant neoplasm of liver primary malignant neoplasm of liver (disorder) primary malignant neoplasm of liver NOS (disorder) resectable malignant neoplasm of the liver choriocarcinoma Choriocarcinoma (disorder) Choriocarcinoma, no ICD-O subtype (morphologic abnormality) Chorioepithelioma Chorioepithelioma NOS DOID:3594 ICD10CM:C58 MSH:D002822 NCI:C2948 SNOMEDCT_US_2015_03_01:188188009 SNOMEDCT_US_2015_03_01:189444004 SNOMEDCT_US_2015_03_01:44769000 UMLS_CUI:C0008497 chorioepithelioma disease_ontology mucinous cystadenocarcinoma A cystadenocarcinoma that derives_from epithelial cells originating in glandular tissue, with a capsulated structure and mucus-producing cells. DOID:3603 MSH:D018282 NCI:C3776 Pseudomucinous cystadenocarcinoma SNOMEDCT_US_2015_03_01:189692006 SNOMEDCT_US_2015_03_01:79143006 UMLS_CUI:C0206699 disease_ontology mucinous cystadenocarcinoma (morphologic abnormality) mucinous cystadenocarcinoma NOS (morphologic abnormality) central nervous system neoplasm "CNS neoplasm" EXACT [CSP2005:2012-5421] "central nervous system tumors" EXACT [NCI2004_11_17:C9293] "neoplasm of central nervous system (disorder)" EXACT [SNOMEDCT_2005_07_31:126951006] MSH2010_2010_02_22:D016543 NCI2009_04D:C9293 SNOMEDCT_2010_1_31:126951006 UMLS_CUI:C0085136 URI: http://www.ebi.ac.uk/cellline#central_nervous_system_neoplasm uterine cancer A female reproductive organ cancer that is located_in the uterus. CA - cancer of uterus Ca uterus NOS DOID:363 DOID:4363 ICD10CM:C55 ICD9CM:179 MSH:D014594 NCI:C3435 NCI:C3552 SNOMEDCT_US_2015_03_01:126908007 SNOMEDCT_US_2015_03_01:156169001 SNOMEDCT_US_2015_03_01:188173004 SNOMEDCT_US_2015_03_01:269613007 SNOMEDCT_US_2015_03_01:371973000 SNOMEDCT_US_2015_03_01:93718007 SNOMEDCT_US_2015_03_01:94127009 Tumour of uterus UMLS_CUI:C0042138 UMLS_CUI:C0153567 disease_ontology malignant neoplasm of uterus (disorder) malignant uterine tumor neoplasm of uterus (disorder) uterine tumor uterus neoplasm skin disease MSH2010_2010_02_22:D012871 NCI2009_04D:C27554 NCI2009_04D:C3371 SNOMEDCT_2010_1_31:156292006 SNOMEDCT_2010_1_31:156396006 SNOMEDCT_2010_1_31:156400006 SNOMEDCT_2010_1_31:156445005 SNOMEDCT_2010_1_31:200580005 SNOMEDCT_2010_1_31:267859000 SNOMEDCT_2010_1_31:267860005 SNOMEDCT_2010_1_31:267873009 SNOMEDCT_2010_1_31:80659006 SNOMEDCT_2010_1_31:95320005 UMLS_CUI:C0037274 URI: http://www.ebi.ac.uk/cellline#skin_disease cervical adenocarcinoma A cervix carcinoma that derives_from epithelial cells of glandular origin. DOID:3702 NCI:C4029 SNOMEDCT_US_2015_03_01:154522004 SNOMEDCT_US_2015_03_01:254887002 SNOMEDCT_US_2015_03_01:269596006 UMLS_CUI:C0279672 adenocarcinoma cervix uteri adenocarcinoma of cervix (disorder) adenocarcinoma of the uterine Cervix disease_ontology ovary adenocarcinoma An ovarian carcinoma that derives_from epithelial cells of glandular origin. DOID:3713 DOID:7816 NCI:C7700 Ovarian adenocarcinoma UMLS_CUI:C0948216 adenocarcinoma of the ovary disease_ontology ovarian adenoacanthoma gastric adenocarcinoma A stomach carcinoma that derives_from epithelial cells of glandular origin. DOID:3717 NCI:C4004 SNOMEDCT_US_2015_03_01:408647009 UMLS_CUI:C0278701 adenocarcinoma of stomach (disorder) disease_ontology stomach adenocarcinoma plasmacytoma "Myeloma - solitary" EXACT [SNOMEDCT_2005_07_31:189507001] "Myeloma, solitary" EXACT [SNOMEDCT_2005_07_31:154644004] "Myeloma, solitary" EXACT [SNOMEDCT_2005_07_31:269652000] "Plasma cell tumor (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:274907000] "Plasma cell tumor NOS (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:190019006] "Plasma cell tumors (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:190016004] "Solitary myeloma (clinical)" EXACT [SNOMEDCT_2005_07_31:109987008] "Solitary myeloma" EXACT [MTHICD9_2006:238.6] "Solitary plasmacytoma of bone (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:10639003] "Solitary plasmacytoma" EXACT [NCI2004_11_17:C6932] "plasma cell neoplasm" EXACT [CSP2005:2004-8110] "plasmacytoma - disorder" EXACT [SNOMEDCT_2005_07_31:302852008] "plasmacytoma - disorder" EXACT [SNOMEDCT_2005_07_31:415112005] "plasmacytoma NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:308122007] "plasmacytoma NOS" EXACT [SNOMEDCT_2005_07_31:188720009] "plasmacytoma NOS" EXACT [SNOMEDCT_2005_07_31:190017008] "plasmacytoma" EXACT [NCI2004_11_17:C9349] MSH2010_2010_02_22:D010954 NCI2009_04D:C6932 NCI2009_04D:C9349 SNOMEDCT_2010_1_31:10639003 SNOMEDCT_2010_1_31:109987008 SNOMEDCT_2010_1_31:154644004 SNOMEDCT_2010_1_31:188719003 SNOMEDCT_2010_1_31:188720009 SNOMEDCT_2010_1_31:189507001 SNOMEDCT_2010_1_31:190016004 SNOMEDCT_2010_1_31:190017008 SNOMEDCT_2010_1_31:190019006 SNOMEDCT_2010_1_31:269652000 SNOMEDCT_2010_1_31:274907000 SNOMEDCT_2010_1_31:302852008 SNOMEDCT_2010_1_31:308122007 SNOMEDCT_2010_1_31:415112005 UMLS_CUI:C0032131 URI: http://www.ebi.ac.uk/cellline#plasmacytoma bladder squamous cell carcinoma A carcinoma of bladder that is manifested in squamous cells of the bladder. DOID:3742 Epidermoid carcinoma of the urinary bladder NCI:C4031 SNOMEDCT_US_2015_03_01:255111004 UMLS_CUI:C0279681 disease_ontology squamous cell carcinoma of bladder (disorder) cervical squamous cell carcinoma A cervix carcinoma that has_material_basis_in squamous cells of the cervix. DOID:3744 NCI:C4028 SNOMEDCT_US_2015_03_01:254886006 UMLS_CUI:C0279671 disease_ontology squamous cell carcinoma of cervix (disorder) squamous cell carcinoma of the Cervix Uteri esophagus squamous cell carcinoma An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus. DOID:3748 MSH:C562729 NCI:C4024 OMIM mapping confirmed by DO. [SN]. OMIM:133239 SCC of esophagus SNOMEDCT_US_2015_03_01:276804009 UMLS_CUI:C0279626 disease_ontology squamous cell carcinoma of esophagus squamous cell carcinoma of esophagus (disorder) male genital cancer male reproductive organ cancer "A cancer of reproductive system that is manifested in the male genital system. This includes organs such as the penis and scrotum." [url:http\://en.wikipedia.org/wiki/Template\:Male_genital_neoplasia, url:http\://www.wrongdiagnosis.com/g/genital_system_cancer/intro.htm] "male genital neoplasm" RELATED [] "male reproductive system neoplasm" EXACT [CSP2005:2016-2462] "neoplasm of male genital organ" EXACT [SNOMEDCT_2005_07_31:126895004] "tumor of male Reproductive system" EXACT [NCI2004_11_17:C3054] A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum. DOID:10284 DOID:3856 ICD10CM:C60-C63 ICD10CM:C63.9 ICD9CM:187.9 MSH2010_2010_02_22:D005834 MSH:D005834 NCI2009_04D:C3054 NCI:C3054 NCI:C8561 SNOMEDCT_2010_1_31:126895004 SNOMEDCT_US_2015_03_01:126895004 SNOMEDCT_US_2015_03_01:190127000 SNOMEDCT_US_2015_03_01:190130007 SNOMEDCT_US_2015_03_01:363515000 SNOMEDCT_US_2015_03_01:93885006 UMLS_CUI:C0017417 UMLS_CUI:C0017417 UMLS_CUI:C0153606 URI: http://www.ebi.ac.uk/cellline#male_genital_cancer disease_ontology male genital cancer male genital neoplasm male reproductive system neoplasm malignant neoplasm of male genital organ or tract malignant neoplasm of male genital organ, NOS malignant neoplasm of male genital organ, site unspecified malignant neoplasm of male genital organ, unspecified (disorder) malignant neoplasm of male genital organs (disorder) malignant tumor of male Reproductive system malignant tumor of male genital organ malignant tumor of male genital organ (disorder) neoplasm of male genital organ tumor of male Reproductive system lung carcinoma A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis. DOID:3905 EFO:0001071 ICD10CM:C34.90 NCI:C4878 OMIM mapping confirmed by DO. [SN]. SNOMEDCT_US_2015_03_01:154485001 SNOMEDCT_US_2015_03_01:187875007 SNOMEDCT_US_2015_03_01:269561006 UMLS_CUI:C0684249 cancer of lung carcinoma of lung disease_ontology lung squamous cell carcinoma A non-small cell lung carcinoma that has_material_basis_in the squamous cell. DOID:3907 Epidermoid cell carcinoma of the lung NCI:C3493 SNOMEDCT_US_2015_03_01:254634000 UMLS_CUI:C0149782 disease_ontology squamous cell carcinoma of lung non-small cell lung carcinoma A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma. DOID:3908 EFO:0003060 KEGG:05223 MSH:D002289 NCI:C2926 NSCLC Non-small cell lung cancer (disorder) SNOMEDCT_US_2015_03_01:254637007 UMLS_CUI:C0007131 disease_ontology lung adenocarcinoma A non-small cell lung carcinoma that derives_from epithelial cells of glandular origin. DOID:3910 DOID:4826 EFO:0000571 MSH:C538231 NCI:C27745 NCI:C3512 SNOMEDCT_US_2015_03_01:254626006 UMLS_CUI:C0152013 UMLS_CUI:C1335060 adenocarcinoma of lung disease_ontology nonsmall cell adenocarcinoma adrenal gland cancer An endocrine gland cancer located_in the adrenal glands which are located above the kidneys. DOID:11007 DOID:3953 ICD10CM:C74 ICD10CM:C74.9 ICD9CM:194.0 MSH:D000310 NCI:C2859 NCI:C9338 SNOMEDCT_US_2015_03_01:127021009 SNOMEDCT_US_2015_03_01:188337000 SNOMEDCT_US_2015_03_01:188338005 SNOMEDCT_US_2015_03_01:363355002 SNOMEDCT_US_2015_03_01:93665005 UMLS_CUI:C0001624 UMLS_CUI:C0750887 adrenal cancer adrenal neoplasm disease_ontology malignant Adrenal tumor malignant neoplasm of adrenal gland neoplasm of adrenal gland (disorder) tumor of the Adrenal gland adrenal cortical adenocarcinoma Adrenal cortex adenocarcinoma Adrenal cortical adenocarcinoma An adrenalcortical carcinoma that originating in the cortex of the adrenal gland and derives_from epithelial cells of glandular origin. DOID:3959 disease_ontology follicular thyroid carcinoma A thyroid carcinoma that has_material_basis_in follicular cells. DOID:3962 Follicular adenocarcinoma (morphologic abnormality) Follicular adenocarcinoma, well differentiated (morphologic abnormality) Follicular carcinoma Follicular carcinoma of the Thyroid gland Follicular thyroid carcinoma (disorder) MSH:D018263 NCI:C8054 OMIM mapping confirmed by DO. [SN]. OMIM:188470 SNOMEDCT_US_2015_03_01:189642005 SNOMEDCT_US_2015_03_01:255028004 SNOMEDCT_US_2015_03_01:28173006 SNOMEDCT_US_2015_03_01:5257006 Thyroid adenocarcinoma UMLS_CUI:C0206682 disease_ontology thyroid carcinoma A thyroid cancer that has_material_basis_in epithelial cells. DOID:3963 EFO:0002892 MSH:D013964 NCI:C4815 UMLS_CUI:C0549473 disease_ontology head and neck cancer, Thyroid papillary thyroid carcinoma A thyroid carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer. DOID:3969 MSH:C536915 NCI:C4035 OMIM mapping confirmed by DO. [SN]. OMIM:188550 Papillary carcinoma of the Thyroid gland SNOMEDCT_US_2015_03_01:255029007 SNOMEDCT_US_2015_03_01:4797003 UMLS_CUI:C0238463 disease_ontology cancer of urinary tract urinary system cancer An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra. DOID:3996 ICD10CM:C68.9 ICD9CM:189.9 ICD9CM_2010:189.9 SNOMEDCT_2010_1_31:190132004 SNOMEDCT_US_2015_03_01:190132004 UMLS_CUI:C0348371 UMLS_CUI:C0348371 URI: http://www.ebi.ac.uk/cellline#cancer_of_urinary_tract disease_ontology disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. DOID:4 MSH:D004194 NCI:C2991 SNOMEDCT_US_2015_03_01:64572001 UMLS_CUI:C0012634 disease_ontology ovarian carcinoma DOID:4001 EFO:0001075 MSH:C538090 NCI:C4908 OMIM mapping confirmed by DO. [SN]. Ovarian carcinoma UMLS_CUI:C0677886 disease_ontology urinary bladder urothelial carcinoma A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder. DOID:4006 NCI:C39851 SNOMEDCT_US_2015_03_01:255109008 SNOMEDCT_US_2015_03_01:393562002 UMLS_CUI:C0279680 bladder transitional cell carcinoma disease_ontology transitional cell carcinoma of bladder (disorder) urothelial bladder carcinoma bladder carcinoma A urinary bladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:4007 EFO:0000292 NCI:C4912 SNOMEDCT_US_2015_03_01:154540000 SNOMEDCT_US_2015_03_01:255108000 SNOMEDCT_US_2015_03_01:269607003 UMLS_CUI:C0699885 carcinoma OF BLADDER carcinoma bladder carcinoma of bladder carcinoma of bladder (disorder) carcinoma of urinary bladder disease_ontology pancreas adenocarcinoma A pancreatic carcinoma that derives_from epithelial cells of glandular origin. DOID:4074 NCI:C8294 SNOMEDCT_US_2015_03_01:700423003 UMLS_CUI:C0281361 adenocarcinoma of the pancreas disease_ontology pancreatic adenocarcinoma Ewings sarcoma-primitive neuroectodermal tumor (PNET) "peripheral Neuroectodermal neoplasm" EXACT [NCI2004_11_17:C9341] "peripheral neuroectodermal tumor (disorder)" EXACT [SNOMEDCT_2005_07_31:253096008] "peripheral neuroectodermal tumor (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:73676002] "peripheral neuroepithelioma (disorder)" EXACT [SNOMEDCT_2005_07_31:254764001] MSH2010_2010_02_22:D018241 NCI2009_04D:C9341 OMIM2009_05_01:612219 SNOMEDCT_2010_1_31:253096008 SNOMEDCT_2010_1_31:254764001 SNOMEDCT_2010_1_31:73676002 UMLS_CUI:C0684337 URI: http://www.ebi.ac.uk/cellline#Ewings_sarcoma-primitive_neuroectodermal_tumor_(PNET) cancer of skin "CA - skin cancer" EXACT [SNOMEDCT_2005_07_31:363511009] "malignant neoplasm of skin (disorder)" EXACT [SNOMEDCT_2005_07_31:372130007] "malignant neoplasm of skin NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:188143008] "malignant neoplasm of skin" EXACT [MTH:NOCODE] "malignant neoplasm of skin, unspecified (disorder)" EXACT [SNOMEDCT_2005_07_31:190107001] "melanoma and Non-melanoma skin cancer" EXACT [NCI2004_11_17:C2920] "skin cancer" EXACT [CSP2005:2020-0536] NCI2009_04D:C2920 SNOMEDCT_2010_1_31:188143008 SNOMEDCT_2010_1_31:190107001 SNOMEDCT_2010_1_31:363511009 SNOMEDCT_2010_1_31:372130007 UMLS_CUI:C0007114 URI: http://www.ebi.ac.uk/cellline#cancer_of_skin endometrial stromal sarcoma DOID:4226 ESS MSH:D018203 NCI:C8973 SNOMEDCT_US_2015_03_01:699356008 SNOMEDCT_US_2015_03_01:70555003 UMLS_CUI:C0206630 Undifferentiated endometrial sarcoma disease_ontology endometrial stromal sarcoma, high grade tissue disease URI: http://www.ebi.ac.uk/cellline#tissue_disease somatostatinoma DOID:4430 MSH:D013005 NCI:C3379 SNOMEDCT_US_2015_03_01:128642005 SNOMEDCT_US_2015_03_01:253006001 Somatostatin cell neoplasm Somatostatin cell tumour Somatostatinoma (disorder) UMLS_CUI:C0037661 disease_ontology renal cell carcinoma A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney. DOID:4450 EFO:0000681 MSH:D002292 NCI:C9385 OMIM:300854 RCC SNOMEDCT_US_2015_03_01:254915003 SNOMEDCT_US_2015_03_01:41607009 SNOMEDCT_US_2015_03_01:702391001 UMLS_CUI:C0007134 Xref MGI. adenocarcinoma of kidney disease_ontology hypernephroma (disorder) renal carcinoma A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products). DOID:4451 NCI:C9384 SNOMEDCT_US_2015_03_01:254915003 UMLS_CUI:C1378703 carcinoma of kidney disease_ontology kidney carcinoma renal clear cell carcinoma A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope. Clear cell carcinoma of kidney (disorder) Clear-cell metastatic renal cell carcinoma DOID:4467 MSH:C538445 added from NeuroDevNet [WAK]. MSH:D002292 NCI:C4033 SNOMEDCT_US_2015_03_01:188251003 SNOMEDCT_US_2015_03_01:254915003 SNOMEDCT_US_2015_03_01:41607009 UMLS_CUI:C0279702 clear cell kidney carcinoma conventional (Clear cell) renal cell carcinoma conventional renal cell carcinoma disease_ontology thyroid sarcoma A thyroid cancer that is located_in the supporting cells of the thyroid. DOID:4515 NCI:C6041 UMLS_CUI:C1336756 disease_ontology sarcoma of the Thyroid gland lung large cell carcinoma DOID:4556 NCI:C4450 SNOMEDCT_US_2015_03_01:254629004 UMLS_CUI:C0345958 disease_ontology large cell carcinoma of lung (disorder) large cell lung carcinoma biliary tract cancer A gastrointestinal system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct. DOID:4607 DOID:8092 ICD10CM:C24.9 ICD9CM:156.9 MSH:D001661 SNOMEDCT_US_2015_03_01:126853008 SNOMEDCT_US_2015_03_01:363415003 SNOMEDCT_US_2015_03_01:93688006 UMLS_CUI:C0005426 UMLS_CUI:C0750952 disease_ontology malignant tumour of biliary tract cancer by anatomical entity "A cancer that affects an anatomical entity." [DO:lh] "malignant neoplasm of aortic body and other paraganglia (disorder)" EXACT [SNOMEDCT_2005_07_31:188343003] "malignant neoplasm of aortic body and other paraganglia" EXACT [] ICD9CM_2010:199 MSH2010_2010_02_22:D009369 NCI2009_04D:C9305 SNOMEDCT_2010_1_31:154432008 SNOMEDCT_2010_1_31:154433003 SNOMEDCT_2010_1_31:154577008 SNOMEDCT_2010_1_31:187597000 SNOMEDCT_2010_1_31:188475001 SNOMEDCT_2010_1_31:188482002 SNOMEDCT_2010_1_31:190150006 SNOMEDCT_2010_1_31:269513004 SNOMEDCT_2010_1_31:269623003 SNOMEDCT_2010_1_31:269626006 SNOMEDCT_2010_1_31:269634000 SNOMEDCT_2010_1_31:363346000 SNOMEDCT_2010_1_31:38807002 UMLS_CUI:C0006826 URI: http://www.ebi.ac.uk/cellline#cancer_by_anatomical_entity breast metaplastic carcinoma DOID:4680 Metaplastic carcinoma of the breast NCI:C5164 UMLS_CUI:C1334708 disease_ontology metaplastic carcinoma of breast malignant neoplasm of nervous system ICD9CM_2010:192 ICD9CM_2010:192.9 SNOMEDCT_2010_1_31:188306000 UMLS_CUI:C0153643 URI: http://www.ebi.ac.uk/cellline#malignant_neoplasm_of_nervous_system male reproductive system disease ICD9CM_2010:600-608.99 ICD9CM_2010:608.9 MSH2010_2010_02_22:D005832 SNOMEDCT_2010_1_31:155905004 SNOMEDCT_2010_1_31:155933004 SNOMEDCT_2010_1_31:155945008 SNOMEDCT_2010_1_31:198089001 SNOMEDCT_2010_1_31:198553004 SNOMEDCT_2010_1_31:64557000 UMLS_CUI:C0017412 URI: http://www.ebi.ac.uk/cellline#male_reproductive_system_disease vascular hemostatic disorder "vascular hemostatic disease (disorder)" EXACT [SNOMEDCT_2005_07_31:21112004] MSH2010_2010_02_22:D020141 SNOMEDCT_2010_1_31:21112004 UMLS_CUI:C0600502 URI: http://www.ebi.ac.uk/cellline#vascular_hemostatic_disorder bile duct carcinoma A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:4897 MSH:D001650 NCI:C27814 SNOMEDCT_US_2015_03_01:70179006 UMLS_CUI:C0740277 disease_ontology pancreatic carcinoma A pancreas cancer that derives_from epithelial cells located_in the pancreas. DOID:4905 EFO:0002618 Exocrine pancreas carcinoma MSH:C562463 NCI:C3850 OMIM mapping confirmed by DO. [SN]. OMIM:260350 Pancreatic carcinoma, familial SNOMEDCT_US_2015_03_01:154475002 SNOMEDCT_US_2015_03_01:255089009 SNOMEDCT_US_2015_03_01:372142002 SNOMEDCT_US_2015_03_01:93938001 UMLS_CUI:C0235974 carcinoma of pancreas carcinoma of pancreas (disorder) disease_ontology exocrine cancer esophagus adenocarcinoma An esophageal carcinoma that derives_from epithelial cells of glandular origin. DOID:4914 MSH:C562730 NCI:C4025 Oesophageal adenocarcinoma NOS SNOMEDCT_US_2015_03_01:276803003 UMLS_CUI:C0279628 adenocarcinoma of esophagus adenocarcinoma of esophagus (disorder) disease_ontology gallbladder carcinoma A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. DOID:4948 NCI:C3844 SNOMEDCT_US_2015_03_01:187782001 SNOMEDCT_US_2015_03_01:255085003 SNOMEDCT_US_2015_03_01:372140005 SNOMEDCT_US_2015_03_01:93810008 UMLS_CUI:C0235782 cancer of the gallbladder carcinoma gallbladder carcinoma of gallbladder (disorder) disease_ontology bone marrow cancer "A bone marrow disease and hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow." [url:http\://nci.nih.gov/dictionary/?CdrID=430857] "Myeloid neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414792005] "Myeloproliferative disease NOS" EXACT [MTHICD9_2006:238.7] "Myeloproliferative disease, NOS" EXACT [SNOMEDCT_2005_07_31:20921005] "Myeloproliferative disease, no ICD-O subtype (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:128925001] "Myeloproliferative disorder (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414794006] "Myeloproliferative disorder" EXACT [SNOMEDCT_2005_07_31:188772004] "Myeloproliferative tumors" EXACT [NCI2004_11_17:C9290] "bone Marrow tumor" EXACT [NCI2004_11_17:C35370] "bone marrow neoplasm" EXACT [CSP2005:2004-0492] "malignant bone Marrow tumor" EXACT [NCI2004_11_17:C35501] "malignant neoplasm of bone marrow" EXACT [] "myeloproliferative disease" EXACT [] "myeloproliferative neoplasm" EXACT [CSP2005:2004-0893] "neoplasm of bone marrow (disorder)" EXACT [SNOMEDCT_2005_07_31:414824005] "primary malignant neoplasm of bone marrow (disorder)" EXACT [SNOMEDCT_2005_07_31:93720005] MSH2010_2010_02_22:D009196 NCI2009_04D:C9290 OMIM2009_05_01:MTHU010939 OMIM2009_05_01:MTHU010948 SNOMEDCT_2010_1_31:128925001 SNOMEDCT_2010_1_31:188772004 SNOMEDCT_2010_1_31:20921005 SNOMEDCT_2010_1_31:414792005 SNOMEDCT_2010_1_31:414794006 SNOMEDCT_2010_1_31:425333006 UMLS_CUI:C0027022 URI: http://www.ebi.ac.uk/cellline#bone_marrow_cancer bone marrow disease "bone Marrow disorder" EXACT [NCI2004_11_17:C34433] "bone marrow disorder (disorder)" EXACT [SNOMEDCT_2005_07_31:127035006] "bone marrow disorder" EXACT [CSP2005:0427-3773] MSH2010_2010_02_22:D001855 NCI2009_04D:C34433 SNOMEDCT_2010_1_31:127035006 UMLS_CUI:C0005956 URI: http://www.ebi.ac.uk/cellline#bone_marrow_disease esophageal cancer A gastrointestinal system cancer that is located_in the esophagus. Ca lower third oesophagus Ca middle third oesophagus DOID:10291 DOID:10292 DOID:10448 DOID:1102 DOID:1104 DOID:5041 ICD10CM:C15.3 ICD10CM:C15.4 ICD10CM:C15.5 ICD9CM:150.2 ICD9CM:150.3 ICD9CM:150.4 ICD9CM:150.5 ICD9CM:150.8 MSH:D004938 NCI:C3028 NCI:C3533 NCI:C3534 NCI:C3535 NCI:C4764 SNOMEDCT_US_2015_03_01:126817006 SNOMEDCT_US_2015_03_01:154443000 SNOMEDCT_US_2015_03_01:154444006 SNOMEDCT_US_2015_03_01:187724003 SNOMEDCT_US_2015_03_01:187725002 SNOMEDCT_US_2015_03_01:187726001 SNOMEDCT_US_2015_03_01:187727005 SNOMEDCT_US_2015_03_01:187729008 SNOMEDCT_US_2015_03_01:269523008 SNOMEDCT_US_2015_03_01:269524002 SNOMEDCT_US_2015_03_01:93656003 SNOMEDCT_US_2015_03_01:93877002 SNOMEDCT_US_2015_03_01:93895004 SNOMEDCT_US_2015_03_01:94119000 UMLS_CUI:C0014859 UMLS_CUI:C0153413 UMLS_CUI:C0153414 UMLS_CUI:C0153415 UMLS_CUI:C0153416 UMLS_CUI:C0496775 disease_ontology esophagus cancer malignant neoplasm of distal third of esophagus malignant neoplasm of lower third of oesophagus malignant neoplasm of middle third of oesophagus malignant neoplasm of proximal third of esophagus malignant neoplasm of upper third esophagus malignant tumor of Distal Third of esophagus malignant tumor of Proximal Third of esophagus malignant tumor of abdominal esophagus malignant tumor of the middle Third of the esophagus thoracic cancer "A cancer by anatomical entity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall." [url:http\://www.advocatehealth.com/cmc/body.cfm?id=203] "Thoracic tumor" EXACT [NCI2004_11_17:C3406] "thorax neoplasm" EXACT [CSP2005:2005-5041] "tumor of thorax (disorder)" EXACT [SNOMEDCT_2005_07_31:255058005] An organ system cancer located_in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall. DOID:3937 DOID:5093 ICD10CM:C76.1 ICD9CM:195.1 MSH2010_2010_02_22:D013899 MSH:D013899 NCI2009_04D:C3406 NCI:C3406 NCI:C3576 SNOMEDCT_2010_1_31:255058005 SNOMEDCT_US_2015_03_01:188361007 SNOMEDCT_US_2015_03_01:188365003 SNOMEDCT_US_2015_03_01:255058005 Thoracic tumor UMLS_CUI:C0039981 UMLS_CUI:C0039981 UMLS_CUI:C0153661 URI: http://www.ebi.ac.uk/cellline#thoracic_cancer disease_ontology thorax cancer thorax neoplasm tumor of thorax (disorder) uterine corpus sarcoma An uterine corpus cancer that is located_in the muscles of the uterus or located_in other tissues that support the uterus. DOID:5165 NCI:C6339 SNOMEDCT_US_2015_03_01:254877001 UMLS_CUI:C0338113 disease_ontology sarcoma of Corpus Uteri sarcoma of uterus (disorder) renal Wilms' tumor DOID:5176 NCI:C6951 Nonanaplastic renal Wilm's tumor UMLS_CUI:C1335062 disease_ontology nonanaplastic renal wilms tumor ovary leiomyosarcoma DOID:5263 NCI:C5234 UMLS_CUI:C1335163 disease_ontology leiomyosarcoma of Ovary cervical clear cell adenocarcinoma Clear cell carcinoma of the Cervix Uteri DOID:5303 NCI:C6344 UMLS_CUI:C1332912 disease_ontology ovarian clear cell adenocarcinoma DOID:5304 NCI:C40078 UMLS_CUI:C1518693 disease_ontology lung small cell carcinoma A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells. DOID:5409 KEGG:05222 MSH:D055752 NCI:C4917 OMIM mapping confirmed by DO. [SN]. OMIM:182280 Oat cell carcinoma of lung (disorder) SCLC SNOMEDCT_US_2015_03_01:254632001 SNOMEDCT_US_2015_03_01:254633006 UMLS_CUI:C0149925 disease_ontology small cell carcinoma of lung small cell carcinoma of lung (disorder) small cell neuroendocrine carcinoma of lung lung oat cell carcinoma DOID:5411 MSH:D018288 NCI:C3915 Oat cell carcinoma (morphologic abnormality) SNOMEDCT_US_2015_03_01:189555001 SNOMEDCT_US_2015_03_01:74364000 SNOMEDCT_US_2015_03_01:76817009 UMLS_CUI:C0262584 disease_ontology oat cell carcinoma poorly differentiated Endocrine neoplasm synovial sarcoma A synovium cancer which develops in the synovial membrane of the joints. DOID:5485 MSH:D013584 NCI:C3400 OMIM:300813 SNOMEDCT_US_2015_03_01:302851001 SNOMEDCT_US_2015_03_01:63211008 UMLS_CUI:C0039101 Xref MGI. disease_ontology stomach carcinoma A stomach cancer that is located_in the stomach. DOID:5517 EFO:0000178 NCI:C4911 SNOMEDCT_US_2015_03_01:154446008 SNOMEDCT_US_2015_03_01:255080008 SNOMEDCT_US_2015_03_01:372143007 UMLS_CUI:C0699791 cancer of the stomach carcinoma of stomach carcinoma of stomach (disorder) disease_ontology gastric carcinoma testicular germ cell cancer A testicular cancer that has_material_basis_in germ cells. DOID:5557 MSH:C563236 NCI:C8591 OMIM:273300 OMIM:300228 ORDO:3636504 UMLS_CUI:C1336708 disease_ontology germ cell tumor of testis testicular germ cell neoplasm mediastinum teratoma DOID:5568 NCI:C6438 UMLS_CUI:C1334682 disease_ontology teratoma of mediastinum kidney disease MSH2010_2010_02_22:D007674 NCI2009_04D:C3149 NCI2009_04D:C34843 OMIM2009_05_01:MTHU006258 SNOMEDCT_2010_1_31:155871008 SNOMEDCT_2010_1_31:266612003 SNOMEDCT_2010_1_31:266624005 SNOMEDCT_2010_1_31:266627003 SNOMEDCT_2010_1_31:274108006 SNOMEDCT_2010_1_31:90708001 UMLS_CUI:C0022658 URI: http://www.ebi.ac.uk/cellline#kidney_disease lung giant cell carcinoma A lung carcinoma that is located_in large undifferentiated cells. DOID:5583 DOID:5584 Giant cell carcinoma Giant cell lung carcinoma MSH:D018286 NCI:C3779 NCI:C4452 SNOMEDCT_US_2015_03_01:254631008 SNOMEDCT_US_2015_03_01:42596004 UMLS_CUI:C0206703 UMLS_CUI:C0345960 disease_ontology acute T cell leukemia CSP:2004-1600 CSP:2004-1803 DOID:5603 ICD10CM:C91.5 ICD10CM:C91.50 MSH:D015459 NCI:C3184 Precursor T Lymphoblastic Leukemia SNOMEDCT_US_2015_03_01:110007008 SNOMEDCT_US_2015_03_01:188729005 SNOMEDCT_US_2015_03_01:77430005 T-cell acute lymphoblastic leukemia (disorder) UMLS_CUI:C0023493 disease_ontology adult acute lymphocytic leukemia DOID:5604 NCI:C4967 UMLS_CUI:C0751606 adult acute lymphoid Leukemia disease_ontology gastric adenosquamous carcinoma Adenosquamous carcinoma of stomach DOID:5635 NCI:C5474 UMLS_CUI:C1333761 disease_ontology large intestine cancer An intestinal cancer that effects the long, tube-like organ that is connected to the small intestine at one end and the anus at the other. DOID:1994 DOID:1997 DOID:5672 ICD10CM:C18.9 MSH:D015179 NCI:C2955 NCI:C4978 NCI:C5105 SNOMEDCT_US_2015_03_01:363510005 SNOMEDCT_US_2015_03_01:408645001 SNOMEDCT_US_2015_03_01:93854002 UMLS_CUI:C0009402 UMLS_CUI:C0346629 UMLS_CUI:C1319315 disease_ontology cribriform carcinoma Cribriform carcinoma DOID:5675 MSH:D000230 NCI:C3680 SNOMEDCT_US_2015_03_01:30156004 UMLS_CUI:C0205643 disease_ontology ductal carcinoma, cribriform type adrenal neuroblastoma An adrenal gland cancer that derives_from immature neuroblastic cells. DOID:5718 NCI:C4827 SNOMEDCT_US_2015_03_01:281562007 UMLS_CUI:C0559460 disease_ontology neuroblastoma of Adrenal gland pediatric lymphoma DOID:5823 NCI:C5165 UMLS_CUI:C1332979 disease_ontology renal pelvis transitional cell carcinoma DOID:5974 NCI:C7355 UMLS_CUI:C0238410 Urothelial cell carcinoma of renal Pelvis disease_ontology lymphoproliferative disorder "Duncan's syndrome" EXACT [SNOMEDCT_2005_07_31:77121009] "Lymphoproliferative disease NOS" EXACT [MTHICD9_2006:238.7] "Lymphoproliferative disease, no ICD-O subtype (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:84631004] "Lymphoproliferative disorder (disorder)" EXACT [SNOMEDCT_2005_07_31:277466009] "Lymphoproliferative disorder (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414629003] "Lymphoproliferative disorder" EXACT [NCI2004_11_17:C9308] MSH2010_2010_02_22:D008232 NCI2009_04D:C9308 SNOMEDCT_2010_1_31:277466009 SNOMEDCT_2010_1_31:414629003 SNOMEDCT_2010_1_31:77121009 SNOMEDCT_2010_1_31:84631004 UMLS_CUI:C0024314 URI: http://www.ebi.ac.uk/cellline#lymphoproliferative_disorder blood protein disorder "blood protein disorder" EXACT [CSP2005:0449-0541] MSH2010_2010_02_22:D001796 UMLS_CUI:C0005830 URI: http://www.ebi.ac.uk/cellline#blood_protein_disorder hereditary disease "Hereditary disease (disorder)" EXACT [SNOMEDCT_2005_07_31:32895009] "Hereditary disease" EXACT [SNOMEDCT_2005_07_31:264530000] "Molecular disease" EXACT [NCI2004_11_17:C3101] "hereditary disorder" EXACT [CSP2005:1254-7727] MSH2010_2010_02_22:D030342 NCI2009_04D:C3101 SNOMEDCT_2010_1_31:264530000 SNOMEDCT_2010_1_31:32895009 UMLS_CUI:C0019247 URI: http://www.ebi.ac.uk/cellline#hereditary_disease connective tissue disease "Connective tissue dis." EXACT [SNOMEDCT_2005_07_31:268048008] "Connective tissue disease" EXACT [MTH:NOCODE] "Connective tissue disease" EXACT [SNOMEDCT_2005_07_31:201432001] "Connective tissue disorder" EXACT [NCI2004_11_17:C26729] "Other musculoskelet/connectiv" EXACT [SNOMEDCT_2005_07_31:268126004] "connective tissue disorder" EXACT [CSP2005:0729-7208] "disorder of connective tissue (disorder)" EXACT [SNOMEDCT_2005_07_31:105969002] MSH2010_2010_02_22:D003240 NCI2009_04D:C26729 SNOMEDCT_2010_1_31:105969002 SNOMEDCT_2010_1_31:201432001 SNOMEDCT_2010_1_31:268048008 SNOMEDCT_2010_1_31:268126004 UMLS_CUI:C0009782 URI: http://www.ebi.ac.uk/cellline#connective_tissue_disease plasma cell neoplasm "Plasma cell disorder (disorder)" EXACT [SNOMEDCT_2005_07_31:277576009] "Plasma cell dyscrasia (disorder)" EXACT [SNOMEDCT_2005_07_31:71390001] "Plasma cell neoplasm (disorder)" EXACT [SNOMEDCT_2005_07_31:415111003] "Plasma cell neoplasm (morphology)" EXACT [SNOMEDCT_2005_07_31:127580003] "Plasma cell tumour" EXACT [SNOMEDCT_2005_07_31:274907000] "Plasmacytic tumor" EXACT [NCI2004_11_17:C4665] MSH2010_2010_02_22:D010265 NCI2009_04D:C4665 SNOMEDCT_2010_1_31:277576009 SNOMEDCT_2010_1_31:71390001 UMLS_CUI:C1136084 URI: http://www.ebi.ac.uk/cellline#plasma_cell_neoplasm inborn errors of metabolism "A simple genetic disease that comprises a large class of genetic diseases involving disorders of metabolism." [url:http\://en.wikipedia.org/wiki/Inborn_errors_of_metabolism] "Inborn Errors of Metabolism" EXACT [NCI2004_11_17:C34816] "Inborn error of metabolism (disorder)" EXACT [SNOMEDCT_2005_07_31:86095007] "Metabolic hereditary disorder" EXACT [SNOMEDCT_2005_07_31:363205007] "inborn metabolism disorder" EXACT [CSP2005:1849-0057] MSH2010_2010_02_22:D008661 NCI2009_04D:C34816 SNOMEDCT_2010_1_31:363205007 SNOMEDCT_2010_1_31:86095007 UMLS_CUI:C0025521 URI: http://www.ebi.ac.uk/cellline#inborn_errors_of_metabolism gastric tubular adenocarcinoma DOID:6595 NCI:C5473 UMLS_CUI:C1333791 disease_ontology tubular adenocarcinoma of stomach hepatocellular carcinoma A liver carcinoma that has_material_basis_in undifferentiated hepatocytes. DOID:5005 DOID:684 EFO:0000182 HCC Hepatoma NCI2009_04D:C7711 NCI2009_04D:C7956 NCI:C7711 NCI:C7956 OMIM mapping confirmed by DO. [SN]. OMIM:114550 UMLS_CUI:C0279607 adult Hepatoma adult primary hepatocellular carcinoma disease_ontology embryonal cancer "A germ cell cancer that is associated with an embryo." [url:http\://www.cancer.gov/dictionary/?CdrID=44250] "embryo neoplasm" EXACT [CSP2005:2000-3997] "embryonal neoplasm" EXACT [NCI2004_11_17:C3264] NCI2009_04D:C3264 OMIM2009_05_01:MTHU006872 UMLS_CUI:C0027654 URI: http://www.ebi.ac.uk/cellline#embryonal_cancer disease of anatomical entity "A disease that manifests in a defined anatomical structure." [DO:wk\,ls, URL:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anatomic] "acellular anatomical structure disease" EXACT [] "disease of anatomical set" EXACT [] "disease of anatomical structure" EXACT [] "disease of material anatomical entity" EXACT [] "disease of physical anatomical entity" EXACT [] "disease of set of heterogenous clusters" EXACT [] URI: http://www.ebi.ac.uk/cellline#disease_of_anatomical_entity mature B-cell lymphocytic neoplasm NCI2009_04D:C27910 UMLS_CUI:C1334633 URI: http://www.ebi.ac.uk/cellline#mature_B-cell_lymphocytic_neoplasm B-cell lymphocytic neoplasm B-cell lymphoma "B-cell neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:413616009] A non-Hodgkin lymphoma that has_material_basis_in B cells. B-cell lymphocytic neoplasm DOID:707 MSH:D016393 NCI2009_04D:C27907 NCI:C27907 NCI:C3457 SNOMEDCT_2010_1_31:413616009 SNOMEDCT_US_2015_03_01:109979007 SNOMEDCT_US_2015_03_01:1929004 SNOMEDCT_US_2015_03_01:413616009 UMLS_CUI:C0079731 UMLS_CUI:C1332362 URI: http://www.ebi.ac.uk/cellline#B-cell_lymphocytic_neoplasm disease_ontology T-cell leukemia DOID:715 MSH:D015458 UMLS_CUI:C0023492 disease_ontology Urologic neoplasm "neoplasm of urinary system (disorder)" EXACT [SNOMEDCT_2005_07_31:126879004] "tumor of the urinary system" EXACT [NCI2004_11_17:C3431] "tumor of urinary tract (disorder)" EXACT [SNOMEDCT_2005_07_31:254913005] "urinary tract neoplasm" EXACT [CSP2005:2021-0179] MSH2010_2010_02_22:D014571 NCI2009_04D:C3431 SNOMEDCT_2010_1_31:126879004 SNOMEDCT_2010_1_31:254913005 UMLS_CUI:C0042076 URI: http://www.ebi.ac.uk/cellline#Urologic_neoplasm hematopoietic system disease "Blood disease (disorder)" EXACT [SNOMEDCT_2005_07_31:267552000] "Blood disease NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:267573000] "Blood disease NOS" EXACT [SNOMEDCT_2005_07_31:154842002] "Blood disease" EXACT [SNOMEDCT_2005_07_31:154785002] "Blood dyscrasia NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:191402006] "Blood dyscrasia NOS" EXACT [MTHICD9_2006:289.9] "Blood/blood forming organ NOS" EXACT [SNOMEDCT_2005_07_31:191446003] "DISEASE OF THE BLOOD AND BLOOD-FORMING ORGANS" EXACT [ICD9CM_2006:280-289.99] "Hematological disease" EXACT [MTH:NOCODE] "Unspecified disease of blood and blood-forming organs" EXACT [ICD9CM_2006:289.9] "blood disorder" EXACT [CSP2005:0427-3600] "disease of blood and/or blood-forming organ (navigational concept)" EXACT [SNOMEDCT_2005_07_31:191124002] "disease of hematopoietic system" EXACT [] "disorder of hematopoietic system (navigational concept)" EXACT [SNOMEDCT_2005_07_31:34093004] ICD9CM_2010:280-289.99 ICD9CM_2010:289.9 MSH2010_2010_02_22:D006402 SNOMEDCT_2010_1_31:154785002 SNOMEDCT_2010_1_31:154842002 SNOMEDCT_2010_1_31:191124002 SNOMEDCT_2010_1_31:191402006 SNOMEDCT_2010_1_31:191446003 SNOMEDCT_2010_1_31:267552000 SNOMEDCT_2010_1_31:267573000 SNOMEDCT_2010_1_31:34093004 UMLS_CUI:C0018939 URI: http://www.ebi.ac.uk/cellline#hematopoietic_system_disease lymphatic system disease "Adenopathy" EXACT [SNOMEDCT_2005_07_31:141342003] "Adenopathy" EXACT [SNOMEDCT_2005_07_31:269044004] "Lymphangiopathy, NOS" EXACT [SNOMEDCT_2005_07_31:3305006] "Lymphatic disease" EXACT [MTH:461] "Lymphatic disease" EXACT [MTH:NOCODE] "Lymphatic disease" EXACT [SNOMEDCT_2005_07_31:155452000] "Lymphatic disease" EXACT [SNOMEDCT_2005_07_31:266326002] "Lymphatic disorder" EXACT [NCI2004_11_17:C3206] "disease of lympoid system" EXACT [] "disorder of lymph node and lymphatics (disorder)" EXACT [SNOMEDCT_2005_07_31:234087005] "disorder of lymphatic system" EXACT [SNOMEDCT_2005_07_31:362971004] "disorder of lymphoid system" EXACT [SNOMEDCT_2005_07_31:111590001] "lymphatic disorder" EXACT [CSP2005:0427-7757] "lympoid system disease" EXACT [] MSH2010_2010_02_22:D008206 NCI2009_04D:C3206 OMIM2009_05_01:MTHU002630 SNOMEDCT_2010_1_31:111590001 SNOMEDCT_2010_1_31:141342003 SNOMEDCT_2010_1_31:155452000 SNOMEDCT_2010_1_31:234087005 SNOMEDCT_2010_1_31:266326002 SNOMEDCT_2010_1_31:269044004 SNOMEDCT_2010_1_31:3305006 SNOMEDCT_2010_1_31:362971004 UMLS_CUI:C0024228 URI: http://www.ebi.ac.uk/cellline#lymphatic_system_disease neuroblastoma An autonomic nervous system neoplasm that derives_from immature nerve cells. DOID:769 EFO:0000621 MSH:D009447 NCI:C3270 OMIM:256700 OMIM:613013 OMIM:613014 OMIM:613015 OMIM:613016 ORDO:635 SNOMEDCT_US_2015_03_01:189931003 SNOMEDCT_US_2015_03_01:269507008 SNOMEDCT_US_2015_03_01:432328008 SNOMEDCT_US_2015_03_01:87364003 UMLS_CUI:C0027819 disease_ontology neuroblastoma (Schwannian Stroma-Poor) gastrointestinal system disease "GIT disease" EXACT [SNOMEDCT_2005_07_31:155629009] "GIT disease" EXACT [SNOMEDCT_2005_07_31:266483008] "GIT disease" EXACT [SNOMEDCT_2005_07_31:53619000] "GIT disorder NOS" EXACT [SNOMEDCT_2005_07_31:155806004] "GIT disorder NOS" EXACT [SNOMEDCT_2005_07_31:266534007] "Gastroenteropathy" EXACT [SNOMEDCT_2005_07_31:25374005] "Non-neoplastic gastrointestinal disorder" EXACT [NCI2004_11_17:C27550] "alimentary system disease" EXACT [] "digestive system disorder" EXACT [] "disease of digestive tract (disorder)" EXACT [SNOMEDCT_2005_07_31:84410009] "disorder of gastrointestinal tract (disorder)" EXACT [SNOMEDCT_2005_07_31:119292006] "gastrointestinal disease and Manifestations" EXACT [NCI2004_11_17:C2990] "gastrointestinal disease" EXACT [] "gastrointestinal disorder" EXACT [CSP2005:1248-3545] "gastrointestinal tract disorder NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:286978000] "gastrointestinal tract disorder NOS" EXACT [SNOMEDCT_2005_07_31:155799006] ICD9CM_2010:520-579.99 MSH2010_2010_02_22:D004066 NCI2009_04D:C2990 SNOMEDCT_2010_1_31:155629009 SNOMEDCT_2010_1_31:155847001 SNOMEDCT_2010_1_31:197575000 SNOMEDCT_2010_1_31:266483008 SNOMEDCT_2010_1_31:53619000 UMLS_CUI:C0012242 URI: http://www.ebi.ac.uk/cellline#gastrointestinal_system_disease gastric signet ring cell adenocarcinoma DOID:8025 NCI:C5250 Signet Ring cell adenocarcinoma of the stomach UMLS_CUI:C1335965 disease_ontology digestive system cancer "A cancer by anatomical entitiy that is manifested in any part of the digestive system." [url:http\://www.wrongdiagnosis.com/d/digestive_system_cancer/intro.htm] "Digestive system neoplasm" EXACT [MTH:NOCODE] "digestive neoplasm" EXACT [CSP2005:4000-0164] "neoplasm of digestive system (disorder)" EXACT [SNOMEDCT_2005_07_31:128348002] "neoplasm of digestive tract" EXACT [SNOMEDCT_2005_07_31:128415001] "neoplasm of unspecified nature of digestive system (disorder)" EXACT [SNOMEDCT_2005_07_31:189527000] "neoplasm of unspecified nature of digestive system" EXACT [ICD9CM_2006:239.0] ICD9CM_2010:239.0 MSH2010_2010_02_22:D004067 SNOMEDCT_2010_1_31:128348002 SNOMEDCT_2010_1_31:128415001 SNOMEDCT_2010_1_31:189527000 UMLS_CUI:C0012243 URI: http://www.ebi.ac.uk/cellline#digestive_system_cancer kidney angiomyolipoma Angiomyolipoma of kidney (disorder) DOID:8411 NCI:C3888 SNOMEDCT_US_2015_03_01:254921004 UMLS_CUI:C0241961 disease_ontology renal Angiomyolipoma chronic myeloid leukemia A myeloid leukemia that is characterized by over production of white blood cells. CML CML - chronic Myelogenous Leukemia DOID:8551 DOID:8552 DOID:8606 EFO:0000339 ICD9CM:205.1 KEGG:05220 MSH:D015464 Myeloid Leukemia, chronic NCI:C3174 OMIM mapping confirmed by DO. [SN]. OMIM:608232 SNOMEDCT_US_2015_03_01:154592009 SNOMEDCT_US_2015_03_01:188735005 SNOMEDCT_US_2015_03_01:63364005 SNOMEDCT_US_2015_03_01:92818009 UMLS_CUI:C0023473 chronic granulocytic leukemia chronic myelogenous leukemia disease_ontology Hodgkin's lymphoma A lymphoma that is marked by the presence of a type of cell called the Reed-Sternberg cell. DOID:0060059 DOID:8567 DOID:8652 DOID:8671 DOID:8685 DOID:8710 DOID:8715 DOID:8841 DOID:8953 DOID:9096 DOID:9107 EFO:0000183 HL Hodgkin disease Hodgkin lymphoma Hodgkin's sarcoma Hodgkins lymphoma ICD10CM:C81 ICD10CM:C81.9 ICD9CM:201 ICD9CM:201.0 ICD9CM:201.1 ICD9CM:201.2 ICD9CM:201.9 MSH:D006689 NCI:C26956 NCI:C6914 NCI:C9357 OMIM:236000 OMIM:300221 OMIM:400021 ORDO:98293 SNOMEDCT_US_2015_03_01:118599009 SNOMEDCT_US_2015_03_01:118602004 SNOMEDCT_US_2015_03_01:118605002 SNOMEDCT_US_2015_03_01:118606001 SNOMEDCT_US_2015_03_01:14537002 SNOMEDCT_US_2015_03_01:154582001 SNOMEDCT_US_2015_03_01:188521005 SNOMEDCT_US_2015_03_01:188522003 SNOMEDCT_US_2015_03_01:188532005 SNOMEDCT_US_2015_03_01:188533000 SNOMEDCT_US_2015_03_01:188542007 SNOMEDCT_US_2015_03_01:188543002 SNOMEDCT_US_2015_03_01:188552006 SNOMEDCT_US_2015_03_01:188595005 SNOMEDCT_US_2015_03_01:188596006 SNOMEDCT_US_2015_03_01:188605006 SNOMEDCT_US_2015_03_01:189987006 SNOMEDCT_US_2015_03_01:189991001 SNOMEDCT_US_2015_03_01:189992008 SNOMEDCT_US_2015_03_01:269509006 SNOMEDCT_US_2015_03_01:309831004 SNOMEDCT_US_2015_03_01:46923007 SNOMEDCT_US_2015_03_01:52337003 SNOMEDCT_US_2015_03_01:70600005 SNOMEDCT_US_2015_03_01:74189002 UMLS_CUI:C0019829 disease_ontology stage I Subdiaphragmatic Hodgkin Lymphoma stage II Subdiaphragmatic Hodgkin Lymphoma Burkitt lymphoma A mature B-cell neoplasm of B-cells found in the germinal center. Burkitt lymphoma/leukaemia Burkitt's Lymphoma Burkitt's tumor Burkitt's tumor or lymphoma DOID:8584 ICD10CM:C83.7 ICD10CM:C83.70 ICD9CM:200.2 MSH:D002051 NCI:C2912 NCI:C7400 OMIM mapping confirmed by DO. [SN]. OMIM:113970 SNOMEDCT_US_2015_03_01:118617000 SNOMEDCT_US_2015_03_01:154581008 SNOMEDCT_US_2015_03_01:188509006 SNOMEDCT_US_2015_03_01:188518008 SNOMEDCT_US_2015_03_01:190022008 SNOMEDCT_US_2015_03_01:190023003 SNOMEDCT_US_2015_03_01:22197008 SNOMEDCT_US_2015_03_01:277571004 SNOMEDCT_US_2015_03_01:397400006 SNOMEDCT_US_2015_03_01:77381001 UMLS_CUI:C0006413 disease_ontology malignant lymphoma, Burkitt's type small Non-Cleaved cell Lymphoma, Burkitt's type gum cancer DOID:8602 DOID:8734 ICD10CM:C03 ICD10CM:C03.9 ICD9CM:143 ICD9CM:143.9 NCI:C9317 SNOMEDCT_US_2015_03_01:187651005 SNOMEDCT_US_2015_03_01:363382005 SNOMEDCT_US_2015_03_01:93819009 UMLS_CUI:C0153364 disease_ontology malignant Gingival tumor malignant neoplasm of gum malignant neoplasm of gum NOS (disorder) malignant neoplasm of other sites of gum malignant neoplasm of other sites of gum (disorder) malignant tumor of gum (disorder) malignant tumour of gingiva oral cavity cancer A gastrointestinal system cancer that is located_in the oral cavity. DOID:0050627 DOID:8617 DOID:8618 DOID:9049 DOID:9055 ICD10CM:C04 ICD10CM:C04.0 ICD10CM:C04.1 ICD10CM:C04.9 ICD9CM:144 ICD9CM:144.0 ICD9CM:144.1 ICD9CM:144.9 NCI:C9318 SNOMEDCT_US_2015_03_01:187652003 SNOMEDCT_US_2015_03_01:187653008 SNOMEDCT_US_2015_03_01:187656000 SNOMEDCT_US_2015_03_01:363385007 SNOMEDCT_US_2015_03_01:93672006 SNOMEDCT_US_2015_03_01:93802007 SNOMEDCT_US_2015_03_01:93860002 UMLS_CUI:C0153368 UMLS_CUI:C0153369 UMLS_CUI:C0496758 disease_ontology malignant neoplasm of anterior portion of floor of mouth malignant neoplasm of floor of mouth malignant neoplasm of lateral floor of mouth malignant neoplasm of lateral portion of floor of mouth malignant tumor of anterior floor of mouth (disorder) malignant tumor of lateral floor of mouth (disorder) malignant tumor of the Floor of the Mouth nervous system disease ICD9CM_2010:349.9 MSH2010_2010_02_22:D009422 NCI2009_04D:C26835 SNOMEDCT_2010_1_31:118940003 SNOMEDCT_2010_1_31:154981003 SNOMEDCT_2010_1_31:155262005 SNOMEDCT_2010_1_31:192641002 SNOMEDCT_2010_1_31:267679005 SNOMEDCT_2010_1_31:286946008 UMLS_CUI:C0027765 URI: http://www.ebi.ac.uk/cellline#nervous_system_disease tongue cancer DOID:8648 DOID:8649 DOID:8779 DOID:8900 DOID:8940 DOID:8999 DOID:9058 DOID:9068 DOID:9196 ICD10CM:C01 ICD10CM:C02.0 ICD10CM:C02.1 ICD10CM:C02.2 ICD10CM:C02.4 ICD10CM:C02.9 ICD9CM:141 ICD9CM:141.0 ICD9CM:141.1 ICD9CM:141.2 ICD9CM:141.3 ICD9CM:141.5 ICD9CM:141.6 ICD9CM:141.9 MSH:D014062 NCI:C3524 NCI:C9345 SNOMEDCT_US_2015_03_01:187632004 SNOMEDCT_US_2015_03_01:187633009 SNOMEDCT_US_2015_03_01:187636001 SNOMEDCT_US_2015_03_01:187637005 SNOMEDCT_US_2015_03_01:187638000 SNOMEDCT_US_2015_03_01:187642002 SNOMEDCT_US_2015_03_01:187644001 SNOMEDCT_US_2015_03_01:187646004 SNOMEDCT_US_2015_03_01:363375006 SNOMEDCT_US_2015_03_01:363376007 SNOMEDCT_US_2015_03_01:363377003 SNOMEDCT_US_2015_03_01:371974006 SNOMEDCT_US_2015_03_01:93687001 SNOMEDCT_US_2015_03_01:93773005 SNOMEDCT_US_2015_03_01:93848003 SNOMEDCT_US_2015_03_01:93868009 SNOMEDCT_US_2015_03_01:94100005 SNOMEDCT_US_2015_03_01:94101009 SNOMEDCT_US_2015_03_01:94134006 Tongue neoplasm malignant stage Unspecified UMLS_CUI:C0153349 UMLS_CUI:C0153350 UMLS_CUI:C0153351 UMLS_CUI:C0153356 UMLS_CUI:C0474963 UMLS_CUI:C0496755 UMLS_CUI:C0684333 disease_ontology malignant neoplasm of anterior 2/3 of tongue unspecified (disorder) malignant neoplasm of anterior two-thirds of tongue, part unspecified malignant neoplasm of base of tongue malignant neoplasm of border of tongue malignant neoplasm of dorsal surface of tongue malignant neoplasm of dorsal tongue NOS malignant neoplasm of dorsum of tongue NOS (disorder) malignant neoplasm of fixed part of tongue NOS malignant neoplasm of fixed part of tongue NOS (disorder) malignant neoplasm of junctional zone of tongue malignant neoplasm of lingual tonsil malignant neoplasm of mobile part of tongue NOS malignant neoplasm of other sites of tongue malignant neoplasm of other sites of tongue (disorder) malignant neoplasm of tip and lateral border of tongue malignant neoplasm of tip and/or lateral border of tongue malignant neoplasm of tongue malignant neoplasm of tongue NOS malignant neoplasm of tongue NOS (disorder) malignant neoplasm of tongue, NOS malignant neoplasm of tongue, tip and lateral border (disorder) malignant neoplasm of ventral surface of tongue malignant neoplasm of ventral tongue surface NOS (disorder) malignant tumor of Posterior Tongue malignant tumor of anterior two-thirds of tongue (disorder) malignant tumor of base of tongue (disorder) malignant tumor of lingual tonsil malignant tumor of lingual tonsil (disorder) malignant tumor of mobile part of tongue malignant tumor of tongue (disorder) lymphosarcoma DOID:8675 DOID:8967 Diffuse lymphoma ICD10CM:C85.9 ICD9CM:200.0 ICD9CM:200.1 ICD9CM:200.7 MSH:D008228 NCI:C26919 NCI:C27824 NCI:C3210 NCI:C3211 NCI:C3458 NCI:C3459 NCI:C3462 NCI:C3463 SNOMEDCT_US_2015_03_01:109964000 SNOMEDCT_US_2015_03_01:118601006 SNOMEDCT_US_2015_03_01:118604003 SNOMEDCT_US_2015_03_01:128929007 SNOMEDCT_US_2015_03_01:134176000 SNOMEDCT_US_2015_03_01:154579006 SNOMEDCT_US_2015_03_01:154580009 SNOMEDCT_US_2015_03_01:154583006 SNOMEDCT_US_2015_03_01:188488003 SNOMEDCT_US_2015_03_01:188497004 SNOMEDCT_US_2015_03_01:188498009 SNOMEDCT_US_2015_03_01:188508003 SNOMEDCT_US_2015_03_01:188675007 SNOMEDCT_US_2015_03_01:188676008 SNOMEDCT_US_2015_03_01:189964003 SNOMEDCT_US_2015_03_01:189965002 SNOMEDCT_US_2015_03_01:189982000 SNOMEDCT_US_2015_03_01:189983005 SNOMEDCT_US_2015_03_01:189986002 SNOMEDCT_US_2015_03_01:190012002 SNOMEDCT_US_2015_03_01:190168009 SNOMEDCT_US_2015_03_01:1929004 SNOMEDCT_US_2015_03_01:269628007 SNOMEDCT_US_2015_03_01:271385002 SNOMEDCT_US_2015_03_01:373168002 SNOMEDCT_US_2015_03_01:40152000 SNOMEDCT_US_2015_03_01:63086004 SNOMEDCT_US_2015_03_01:67824002 UMLS_CUI:C0024302 UMLS_CUI:C0024304 UMLS_CUI:C0024305 UMLS_CUI:C0024306 UMLS_CUI:C0079740 UMLS_CUI:C0079741 UMLS_CUI:C0079747 UMLS_CUI:C0079757 UMLS_CUI:C0079770 UMLS_CUI:C3714542 disease_ontology malignant lymphoma (category) myeloid leukemia A leukemia that is located_in myeloid tissue. DOID:8692 DOID:8878 DOID:8879 DOID:8910 DOID:9066 DOID:9126 ICD10CM:C92 ICD10CM:C92.9 ICD10CM:C92.90 ICD9CM:205 ICD9CM:205.9 LEUKEMIA MYELOGENOUS MSH:D007951 Myelogenous Leukemia in Remission Myeloid leukaemia Myeloid leukaemia (category) Myeloid leukemia Myeloid leukemia (disorder) Myeloid leukemia NOS (disorder) Myeloid leukemia in remission (disorder) Myeloid leukemia, NOS, without mention of remission Myeloid leukemia, disease (disorder) Myeloid leukemia, disease [Ambiguous] Myeloid leukemia, no ICD-O subtype (morphologic abnormality) Myeloid leukemias (morphologic abnormality) NCI:C3172 Non-Lymphocytic Leukemia Other myeloid leukemia Other myeloid leukemia (disorder) Other myeloid leukemia (morphologic abnormality) Other myeloid leukemia NOS (disorder) Other myeloid leukemia NOS (morphologic abnormality) Other myeloid leukemia in remission Other myeloid leukemia without mention of remission SNOMEDCT_US_2015_03_01:128934006 SNOMEDCT_US_2015_03_01:154587007 SNOMEDCT_US_2015_03_01:188732008 SNOMEDCT_US_2015_03_01:188743000 SNOMEDCT_US_2015_03_01:190047005 SNOMEDCT_US_2015_03_01:269631008 SNOMEDCT_US_2015_03_01:324170002 SNOMEDCT_US_2015_03_01:37810007 SNOMEDCT_US_2015_03_01:94717009 UMLS_CUI:C0023470 Unspecified myeloid leukemia in remission Unspecified myeloid leukemia without mention of remission disease_ontology myeloid granulocytic leukemia neuropathy "Neuropathy (disorder)" EXACT [SNOMEDCT_2005_07_31:264554005] "Neuropathy (disorder)" EXACT [SNOMEDCT_2005_07_31:386033004] "Neuropathy" EXACT [MTH:NOCODE] "Neuropathy" EXACT [SNOMEDCT_2005_07_31:193167000] "Neuropathy" EXACT [SNOMEDCT_2005_07_31:277317008] "Neuropathy" EXACT [SNOMEDCT_2005_07_31:277878001] "Neuropathy, NOS" EXACT [SNOMEDCT_2005_07_31:42658009] NCI2009_04D:C4731 OMIM2009_05_01:MTHU016030 SNOMEDCT_2010_1_31:193167000 SNOMEDCT_2010_1_31:264554005 SNOMEDCT_2010_1_31:277317008 SNOMEDCT_2010_1_31:277878001 SNOMEDCT_2010_1_31:386033004 SNOMEDCT_2010_1_31:42658009 UMLS_CUI:C0442874 URI: http://www.ebi.ac.uk/cellline#neuropathy soft tissue disease "Connective and soft tissue disease" EXACT [NCI2004_11_17:C27574] "Connective and soft tissue disorder" EXACT [MTH:NOCODE] "disease of deep fascial system" EXACT [] NCI2009_04D:C27574 UMLS_CUI:C1333150 URI: http://www.ebi.ac.uk/cellline#soft_tissue_disease acute monocytic leukemia CSP:2004-2820 DOID:8864 DOID:9208 ICD9CM:206.0 MSH:D007948 OMIM mapping confirmed by DO. [SN]. OMIM:151380 SNOMEDCT_US_2015_03_01:154594005 SNOMEDCT_US_2015_03_01:22331004 SNOMEDCT_US_2015_03_01:413441006 SNOMEDCT_US_2015_03_01:91859000 UMLS_CUI:C0023465 acute Monoblastic Leukemia and acute Monocytic Leukemia acute monocytic leukemia without mention of remission acute monocytic leukemia, FAB M5 (disorder) acute monocytic leukemia, morphology (morphologic abnormality) disease_ontology acute myeloid leukemia A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML - acute Myeloid Leukemia DOID:9118 DOID:9119 DOID:9171 ICD10CM:C92.0 ICD10CM:C92.00 ICD9CM:205.0 KEGG:05221 Leukemia, Myelocytic, acute MSH:D015470 NCI:C27753 NCI:C3171 OMIM mapping confirmed by DO. [SN]. OMIM:601626 OMIM:602439 SNOMEDCT_US_2015_03_01:154591002 SNOMEDCT_US_2015_03_01:17788007 SNOMEDCT_US_2015_03_01:277600006 SNOMEDCT_US_2015_03_01:413443009 SNOMEDCT_US_2015_03_01:91861009 UMLS_CUI:C0023467 acute myeloblastic leukemia acute myelogenous leukemia disease_ontology submandibular gland cancer DOID:9173 ICD10CM:C08.0 ICD9CM:142.1 NCI:C3526 SNOMEDCT_US_2015_03_01:363380002 SNOMEDCT_US_2015_03_01:94077005 UMLS_CUI:C0153360 disease_ontology malignant neoplasm of submaxillary gland malignant tumor of submandibular gland (disorder) malignant tumor of the Submandibular gland colorectal cancer A large intestine cancer that is located_in the colon and/or located_in the rectum. DOID:9256 KEGG:05210 MSH:D015179 OMIM:114500 OMIM:608812 OMIM:611469 OMIM:612229 OMIM:612230 OMIM:612231 OMIM:612232 OMIM:612589 OMIM:612590 OMIM:612591 OMIM:612592 OMIM:615083 UMLS_CUI:C1527249 disease_ontology brain disease MSH2010_2010_02_22:D001927 SNOMEDCT_2010_1_31:81308009 UMLS_CUI:C0006111 URI: http://www.ebi.ac.uk/cellline#brain_disease multiple myeloma and immunoproliferative neoplasm ICD9CM_2010:203 SNOMEDCT_2010_1_31:188717001 UMLS_CUI:C0153867 URI: http://www.ebi.ac.uk/cellline#multiple_myeloma_and_immunoproliferative_neoplasm acute lymphocytic leukemia A lymphoblastic leukemia that is characterized by over production of lymphoblasts. DOID:9952 EFO:0000220 ICD10CM:C91.0 ICD10CM:C91.00 ICD9CM:204.0 NCI:C3167 OMIM:247640 OMIM:613065 OMIM:613067 OMIM:615545 ORDO:513 SNOMEDCT_US_2015_03_01:128822004 SNOMEDCT_US_2015_03_01:154588002 SNOMEDCT_US_2015_03_01:190034000 SNOMEDCT_US_2015_03_01:90151006 SNOMEDCT_US_2015_03_01:91857003 UMLS_CUI:C0023449 Xref MGI. acute lymphoblastic leukemia disease_ontology objective specification 2009-03-16: original definition when imported from OBI read: "objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed." 2014-03-31: In the example of usage ("In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that. Answers the question, why did you do this experiment? In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction. OBI Plan and Planned Process/Roles Branch OBI_0000217 PERSON: Alan Ruttenberg PERSON: Barry Smith PERSON: Bjoern Peters PERSON: Jennifer Fostel a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved. goal specification objective specification action specification Alan Ruttenberg OBI Plan and Planned Process branch Pour the contents of flask 1 into flask 2 a directive information entity that describes an action the bearer will take action specification data item 2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers. 2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/ 2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum. 2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym. Data items include counts of things, analyte concentrations, and statistical summaries. PERSON: Alan Ruttenberg PERSON: Chris Stoeckert PERSON: Jonathan Rees a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. data data item information content entity 2014-03-10: The use of "thing" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ). A generically dependent continuant that is about some thing. Examples of information content entites include journal articles, data, graphical layouts, and graphs. OBI_0000142 PERSON: Chris Stoeckert an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity information content entity directive information entity 2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was "is the specification of a process that can be concretized and realized by an actor" with alternative term "instruction".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term. 2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it. 8/6/2009 Alan Ruttenberg: Changed label from "information entity about a realizable" after discussions at ICBO An information content entity whose concretizations indicate to their bearer how to realize them in a process. PERSON: Alan Ruttenberg PERSON: Bjoern Peters Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan directive information entity curation status specification Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting) GROUP:OBI:<http://purl.obolibrary.org/obo/obi> OBI_0000266 PERSON:Bill Bug The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. curation status specification data about an ontology part Person:Alan Ruttenberg data about an ontology part data about an ontology part is a data item about a part of an ontology, for example a term plan specification 2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was " a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term. 2014-03-31: A plan specification can have other parts, such as conditional specifications. A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified. Alan Ruttenberg Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved OBI Plan and Planned Process branch OBI_0000344 PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice. plan specification Muridae Muridae Mus musculus "Mus muscaris" RELATED misnomer [] "house mouse" EXACT genbank_common_name [] "mice C57BL/6xCBA/CaJ hybrid" RELATED misspelling [] "mouse" EXACT common_name [] GC_ID:1 Mus musculus URI: http://www.ebi.ac.uk/cellline#Mus_musculus house mouse mouse Viruses Viruses Euteleostomi Euteleostomi bony vertebrates Bacteria Bacteria eubacteria Homininae Homininae Archaea Archaea Eukaryota Eukaryota eucaryotes eukaryotes Euarchontoglires Euarchontoglires Glires "Rodents and rabbits" EXACT genbank_common_name [] GC_ID:1 Glires Rodents and rabbits URI: http://www.ebi.ac.uk/cellline#Glires Simiiformes Simiiformes Hominoidea "ape" EXACT common_name [] "apes" EXACT common_name [] GC_ID:1 Hominoidea URI: http://www.ebi.ac.uk/cellline#Hominoidea ape apes Tetrapoda Tetrapoda tetrapods Amniota Amniota amniotes Theria <Mammalia> Theria Theria <Mammalia> Opisthokonta Opisthokonta Bilateria Bilateria Sciurognathi Sciurognathi Muroidea Muroidea Murinae Murinae Mammalia "mammals" EXACT genbank_common_name [] "mammals" RELATED blast_name [] GC_ID:1 Mammalia URI: http://www.ebi.ac.uk/cellline#Mammalia mammals Vertebrata <Metazoa> Vertebrata Vertebrata <Metazoa> vertebrates Craniata <chordata> Craniata Craniata <chordata> Eutheria Eutheria eutherian mammals placental mammals placentals Primates "Primata" RELATED synonym [] "primate" EXACT equivalent_name [] "primates" RELATED blast_name [] GC_ID:1 Primates URI: http://www.ebi.ac.uk/cellline#Primates primate Catarrhini Catarrhini Hominidae "Pongidae" RELATED synonym [] "great apes" EXACT common_name [] GC_ID:1 Hominidae URI: http://www.ebi.ac.uk/cellline#Hominidae great apes Homo sapiens "human" EXACT genbank_common_name [] GC_ID:1 Homo sapiens URI: http://www.ebi.ac.uk/cellline#Homo_sapiens human human being man Rodentia "rodents" EXACT genbank_common_name [] "rodents" RELATED blast_name [] GC_ID:1 Rodentia URI: http://www.ebi.ac.uk/cellline#Rodentia rodents planned process 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.) 6/11/9: Edited at workshop. Used to include: is initiated by an agent Bjoern Peters Injecting mice with a vaccine in order to test its efficacy branch derived A processual entity that realizes a plan which is the concretization of a plan specification. This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call) planned process processed material Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples Is a material entity that is created or changed during material processing. PERSON: Alan Ruttenberg processed material culture medium a processed material that provides the needed nourishment for microorganisms or cells grown in vitro. A growth medium or culture medium is a substance in which microorganisms or cells can grow. Wikipedia, growth medium, Feb 29, 2008 OBI Person: Jennifer Fostel, Jie Zheng culture medium material processing A cell lysis, production of a cloning vector, creating a buffer. PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca Serra A planned process which results in physical changes in a specified input material OBI branch derived PERSON: Bjoern Peters material processing material transformation organization organization An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. EFO_URI: http://www.ebi.ac.uk/efo/EFO_0002010 GROUP: OBI James Malone Jie Zheng MO_177 PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Philippe Rocca-Serra PERSON: Susanna Sansone Tomasz Adamusiak organisation An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods. organization material transformation objective GROUP: OBI PlanAndPlannedProcess Branch PERSON: Bjoern Peters PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS. an objective specifiction that creates an specific output object from input materials. artifact creation objective material transformation objective material separation objective PPPB branch PPPB branch The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood. is an objective to transform a material entity into spatially separated components. material separation objective portioning objective A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material. The objective to obtain multiple aliquots of an enzyme preparation. portioning objective separation into different composition objective A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities). The objective to obtain cells contained in a sample of blood. We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives separation into different composition objective material maintenance objective An objective specification maintains some or all of the qualities of a material over time. PERSON: Bjoern Peters material maintenance objective PERSON: Bjoern Peters material maintenance a process with that achieves the objective to maintain some or all of the characteristics of an input material over time material maintenance secondary cultured cell A cultured cell that has been passaged or derives from a cell that has been passaged in culture. A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture. PERSON: Matthew Brush The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. secondary cultured cell Person: Matthew Brush establishing cell line a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics (e.g. immortalization or some other stable genetic modification, or selection of some defined subset). Person: Matthew Brush establishing cell line 2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and progatated over time. PERSON:Matthew Brush secondary cultured cell population secondary cultured cell population The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. PERSON:Matthew Brush A cultured cell population that is derived through one or more passages in culture. PERSON:Matthew Brush secondary cell culture sample The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. cell freezing medium A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. PERSON: Matthew Brush cell freezing medium culture media or serum + 10% DMSO is often used as cell freezing media. organism organism 10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms') A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. E.g Drosophila melanogaster Drosophila melanogaster EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000634 GROUP: OBI Biomaterial Branch James Malone Jie Zheng MO_508 NIFSTD:birnlex_376 Tomasz Adamusiak A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. WEB: http://en.wikipedia.org/wiki/Organism animal fungus organism plant virus cultured cell population A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. PERSON:Matthew Brush PERSON:Matthew Brush The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. cultured cell population 2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line. cell culture sample material component separation Bjoern Peters IEDB Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification a material processing in which components of an input material become segregated in space material component separation maintaining cell culture OBI branch derived PlanAndPlannedProcess Branch When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing maintaining cell culture establishing cell culture PERSON:Matthew Brush a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line). establishing cell culture A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics. This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms. PERSON:Matthew Brush cell culture splitting cell culture passaging An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone. OBI branch derived PlanAndPlannedProcess Branch The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media. The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing cell culture splitting uterine cervix BTO:0001421 BTO:0002249 CALOHA:TS-0134 EFO:0000979 EMAPA:29927 EV:0100114 FMA:17740 GAID:376 Lower, narrow portion of the uterus where it joins with the top end of the vagina. MA:0000392 MAT:0000292 MESH:A05.360.319.679.256 OpenCyc:Mx4rvVipEJwpEbGdrcN5Y29ycA The evolution of mammals is associated with radical changes in their reproductive biology, particularly the structure and function of the female reproductive organs. These changes include the evolution of the uterus, cervix, vagina, placenta and specialized cell types associated with each of those structures.[well established][VHOG] The narrow caudal end of the uterus that opens into the vagina. [TFD][VHOG] UBERON:0000002 UMLS:C0007874 VHOG:0001359 canalis cervicis uteri caudal segment of uterus cervical cervical canal cervical canal of uterus cervix cervix of uterus cervix uteri galen:CervixUteri neck of uterus uberon uterine cervix somatic nervous system EFO:0000892 FMA:9904 MA:0002850 MAT:0000099 MAT:0000342 MIAA:0000099 MIAA:0000342 PNS - somatic Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. UBERON:0000012 WBbt:0005760 somatic nervous system, somatic division somatic peripheral nervous system uberon zone of skin Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee (...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG] Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. EHDAA2:0001844 EHDAA:6530 EMAPA:17525 EV:0100152 FMA:86166 GAID:933 MA:0000151 MAT:0000284 MESH:A17.815 MIAA:0000284 OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA UBERON:0000014 VHOG:0000860 portion of skin region of skin skin skin region skin zone uberon we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive sense organ AEO:0000094 An organ that is capable of transducing sensory stimulus to the nervous system. BSA:0000121 BTO:0000202 CALOHA:TS-2043 EHDAA2:0001824 EHDAA:500 EMAPA:16192 EMAPA:35955 FBbt:00005155 GAID:63 HAO:0000930 MA:0000017 MESH:A09 Sinnesorgan UBERON:0000020 UMLS:C0935626 VHOG:0001407 WBbt:0006929 organ of sense organ system organ of sensory organ system organ of sensory system sense organ system organ sensillum sensor sensory organ sensory organ system organ sensory system organ uberon tube Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. UBERON:0000025 anatomical tube duct galen:Tube not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts) tubular uberon appendage AEO:0000193 An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA][BILA:0000018]. BILA:0000018 BTO:0001492 CARO:0010003 EFO:0000799 EHDAA2:0003193 EV:0100155 FBbt:00007000 HAO:0000144 MAT:0000023 MESH:A01.378 MIAA:0000023 Major subdivision of an organism that protrudes from the body[DOS, CARO]. OpenCyc:Mx4rvViC-JwpEbGdrcN5Y29ycA Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified][GO:0048736]. UBERON:0000026 UMLS:C0598782 VSAO:0000075 XAO:0000218 appendages appendicular extremitaet extremity limbs/digits/tail this is currently a subtype of organism subdivision - which would exclude feathers uberon follicular fluid BTO:0004383 CALOHA:TS-0728 FMA:18665 GAID:372 MA:0002511 MESH:A05.360.319.114.630.535.150 The fluid surrounding the ovum and granulosa cells in the ovarian follicle.. The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes and is rich in hyaluronic acid. UBERON:0000038 UMLS:C1709369 antral fluid, ovarian follicle liquor follicularis liquor folliculi liquor folliculi ovarian follicular fluid ovary follicle fluid ovary follicular fluid uberon serous membrane A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO] FMA:9581 GAID:19 MESH:A10.615.789 TAO:0005425 UBERON:0000042 UMLS:C0036760 ZFA:0005425 a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP] in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA. multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. serosa tunica serosa uberon wall of serous sac spherical lensed eye UBERON:0000049 simple eye that consists of a lens of one refractive index uberon vessel A tubular structure that contains, conveys body fluid, such as blood or lymph. UBERON:0000055 uberon ureter AAO:0010254 Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO] BTO:0001409 CALOHA:TS-1084 EFO:0000930 EHDAA2:0002139 EHDAA:9341 EMAPA:17950 EV:0100097 FMA:9704 GAID:438 MA:0000378 MAT:0000120 MESH:A05.810.776 MIAA:0000120 Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. OpenCyc:Mx4rvhmm6JwpEbGdrcN5Y29ycA The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG] UBERON:0000056 UMLS:C0041951 VHOG:0000605 XAO:0000144 galen:Ureter in humans, consists of adventitial, muscular and mucoa layers metanephric duct uberon ureteral ureteric anatomical structure AAO:0010825 AEO:0000003 BILA:0000003 CARO:0000003 EHDAA2:0003003 EMAPA:0 FBbt:00007001 FMA:67135 GAID:781 HAO:0000003 MA:0003000 MESH:A13 Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. TAO:0000037 TGMA:0001823 UBERON:0000061 VHOG:0001759 WBbt:0000100 XAO:0003000 ZFA:0000037 biological structure connected biological structure uberon organ Anatomical structure that performs a specific function or group of functions [WP]. CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4 CARO:0020004 EFO:0000634 EMAPA:35949 ENVO:01000162 FMA:67498 MA:0003001 OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. UBERON:0000062 UMLS:C0178784 WBbt:0003760 anatomical unit body organ element uberon organ part AAO:0011124 Anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas[FMA]. EFO:0000635 FMA:82472 UBERON:0000064 cardinal organ part regional part of organ uberon embryo stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. BilaDO:0000002 EV:0300001 FBdv:00005289 HsapDv:0000002 MmusDv:0000002 OGES:000000 OGES:000022 UBERON:0000068 WBls:0000003 WBls:0000092 WBls:0000102 XAO:1000012 embryogenesis embryonic stage uberon mixed endoderm/mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple UBERON:0000077 uberon life cycle stage A spatiotemporal region encompassing some part of the life cycle of an organism. BILS:0000105 EFO:0000399 FBdv:00007012 HsapDv:0000000 MmusDv:0000000 OlatDv:0000010 PdumDv:0000090 UBERON:0000105 WBls:0000002 XAO:1000000 ZFS:0000000 ZFS:0100000 developmental stage stage the WBls class 'all stages' belongs here as it is the superclass of other WBls stages this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here uberon we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage pelvic fin BTO:0004651 EFO:0003644 Paired fin located in the abdominal position of the body. Paired fin located in the abdominal position of the body.[TAO] Paired fin located in the abdominal position of the body.[VSAO] TAO:0001184 UBERON:0000152 VSAO:0000129 ZFA:0001184 ischioptérygie@fr nageoire pelvienne@fr uberon intestine AAO:0000246 ANISEED:1235303 BSA:0000093 BTO:0000648 CALOHA:TS-0490 EFO:0000834 EMAPA:32874 EMAPA:35180 EV:0100071 FMA:7199 GAID:295 In zebrafish, No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type. MA:0000328 MA:0001524 MESH:A03.492.411 MIAA:0000043 Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.[AAO] Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. TAO:0001338 The tract of the alimentary canal. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] This class is probably too inclusive UBERON:0000160 UMLS:C0021853 VHOG:0000056 WBbt:0005772 XAO:0000129 ZFA:0001338 bowel galen:Intestine intestinal intestinal tract uberon orifice Anatomical conduit that connects two adjacent body spaces, surrounded by two or more subdivisions of two or more organs. Examples: right atrioventricular orifice, orifice of artery, hilum of kidney, porta hepatis[FMA,modified]. FMA:3724 UBERON:0000161 anatomical orifice anatomical ostium hilum in FMA, this is an anatomical conduit *space*, rather than anatomical conduit uberon mouth AAO:0010355 BTO:0001090 BTO:0004698 CALOHA:TS-1315 Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO] EFO:0000825 EHDAA2:0001326 EHDAA:542 EMAPA:16262 FBbt:00003126 FMA:49184 GAID:75 MA:0000341 MA:0002474 MAT:0000038 MESH:A01.456.505.631 MIAA:0000038 Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG] OpenCyc:Mx4rvVidh5wpEbGdrcN5Y29ycA TADS:0000040 TAO:0000547 TAO:0000590 TGMA:0000131 The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). UBERON:0000165 VHOG:0000280 VHOG:0000812 XAO:0003029 ZFA:0000547 ZFA:0000590 adult mouth cavital oralis cavitas oris cavum oris galen:Mouth in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips mouth cavity oral oral region oral vestibule regio oralis rima oris some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives stoma stomatodaeum trophic apparatus uberon vestibule of mouth vestibulum oris pair of lungs FMA:68877 OpenCyc:Mx4rvVjKy5wpEbGdrcN5Y29ycA UBERON:0000170 lungs lungs pair pulmones set of lungs uberon breast BTO:0000149 CALOHA:TS-2083 EV:0100124 FMA:9601 GAID:33 MESH:A01.236 OpenCyc:Mx4rvVjV7ZwpEbGdrcN5Y29ycA The breasts of a female primate’s body contain the mammary glands, which secrete milk used to feed infants. Both men and women develop breasts from the same embryological tissues. However, at puberty female sex hormones, mainly estrogens, promote breast development, which does not happen with men. As a result women's breasts become more prominent than men's. The upper ventral region of an animal's torso. UBERON:0000310 UMLS:C0006141 galen:Breast mamma mammary part of chest mammary region uberon mucosa A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] AEO:0000199 BTO:0000886 CALOHA:TS-2031 EHDAA2_RETIRED:0003234 EV:0100382 FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately FMA:85355 FMA:85358 GAID:297 MESH:A10.615.550 OpenCyc:Mx4rvmKNOpwpEbGdrcN5Y29ycA UBERON:0000344 UMLS:C0026724 galen:Mucosa mucosa of organ mucosa of organ part mucosal mucosal region mucous membrane organ mucosa region of mucosa tunica mucosa uberon septum of telencephalon BAMS:SA BAMS:SEP BAMS:Sep BAMS:Spt BM:Tel-Spt BTO:0002705 EMAPA:32837 FMA:61842 Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996). MA:0000924 MESH:A08.186.211.577.750 Se Septal region Subdivision of the telencephalon on the midline between the lateral ventricles which contains the septum pellucidum and the septal nuclei[FMA][FMA:61842]. UBERON:0000446 UMLS:C0752060 area septalis http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=255 massa praecommissuralis septal area septum septum (NN) septum pellucidum (BNA,PNA) septum telencephali telencephalon septum uberon organism substance AAO:0010839 AEO:0000004 BILA:0000004 CALOHA:TS-2101 CARO:0000004 EHDAA2:0003004 EMAPA:35178 FBbt:00007019 FMA:9669 HAO:0000004 MA:0002450 Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. SPD:0000008 TAO:0001487 TGMA:0001824 UBERON:0000463 VHOG:0001726 XAO:0004001 ZFA:0001487 body fluid or substance body substance galen:BodySubstance organism substance portion of body substance uberon material anatomical entity AAO:0010264 AEO:0000006 Anatomical entity that has mass. BILA:0000006 CARO:0000006 EHDAA2:0003006 FBbt:00007016 FMA:67165 HAO:0000006 TAO:0001836 TGMA:0001826 UBERON:0000465 VHOG:0001721 uberon multicellular organism AAO:0010026 AEO:0000191 Anatomical structure that is an individual member of a species and consists of more than one cell. BILA:0000012 BSA:0000038 BTO:0000042 CARO:0000012 EFO:0002906 EHDAA2:0003103 EHDAA2:0003191 EHDAA:1 EHDAA:9178 EMAPA:25765 EV:0100016 FBbt:00000001 FMA:256135 HAO:0000012 Koerper TADS:0000001 TAO:0001094 TGMA:0001832 TODO - split body and mc organism? body continues after death stage UBERON:0000468 VHOG:0000671 WBbt:0007833 XAO:0003004 ZFA:0001094 animal body galen:Organism multi-cellular organism organism organismal uberon whole body whole organism testis (...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG] A gonad of a male animal. A gonad produces and releases sperm. AAO:0000606 BILA:0000124 BSA:0000085 BTO:0001363 CALOHA:TS-1030 EFO:0000984 EHDAA2:0002007 EHDAA:8146 EMAPA:17972 EV:0100102 FBbt:00004928 FMA:7210 GAID:396 HAO:0001007 MA:0000411 MAT:0000132 MESH:A05.360.444.849 MIAA:0000132 Male reproductive organ.[TAO] OpenCyc:Mx4rvVjM25wpEbGdrcN5Y29ycA TAO:0000598 The testes are descended in metatherian and eutherian mammals, first transabdominally, then inguinoscrotally UBERON:0000473 UBERON:0002117 UMLS:C0039597 VHOG:0000252 WBbt:0006794 XAO:0000157 ZFA:0000598 galen:Testis gonad of male genitalia gonad of male reproductive system male gonad orchis testes testicle testicular testiculus uberon organism subdivision AAO:0010053 AEO:0000032 Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. BILA:0000032 CALOHA:TS-2084 CARO:0000032 EFO:0000808 EHDAA2:0003032 EMAPA:36031 FBbt:00007009 FMA:7153 HAO:0000032 MA:0002433 MAT:0000293 MESH:A01 MIAA:0000293 OpenCyc:Mx4rvViAHJwpEbGdrcN5Y29ycA Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency TAO:0001308 TGMA:0001840 UBERON:0000475 UMLS:C0229962 VHOG:0001758 XAO:0003013 ZFA:0001308 anatomic region body part body region cardinal body part galen:BodyPart uberon anatomical cluster AAO:0010009 AEO:0000041 Anatomical group that has its parts adjacent to one another. BILA:0000041 CARO:0000041 EHDAA2:0003041 FBbt:00007277 FMA:49443 HAO:0000041 TADS:0000605 TAO:0001478 TGMA:0001842 UBERON:0000477 VHOG:0001737 Will be obsoleted in CARO v2 [https://github.com/obophenotype/caro/issues/3] XAO:0003160 ZFA:0001478 uberon extraembryonic structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. AAO:0010020 AEO:0000042 BILA:0000042 CALOHA:TS-2119 CARO:0000042 EHDAA2:0003042 EHDAA:46 FBbt:00005835 FMA:85537 HAO:0000042 TAO:0000020 TGMA:0001843 UBERON:0000478 UMLS:C1282438 VHOG:0000292 XAO:0004005 ZFA:0000020 extra-embryonic structure extraembryonic tissue see also conceptus extraembryonic component in EHDAA2. uberon tissue AAO:0000607 AAO:0010054 AEO:0000043 BILA:0000043 CALOHA:TS-2090 CARO:0000043 EHDAA2:0003043 EMAPA:35868 FBbt:00007003 FMA:9637 HAO:0000043 MA:0003002 MESH:A10 Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. TAO:0001477 TGMA:0001844 UBERON:0000479 UMLS:C0040300 VHOG:0001757 WBbt:0005729 XAO:0003040 ZFA:0001477 changed label and definition to reflect CARO2 galen:Tissue portion of tissue simple tissue tissue portion uberon cavitated compound organ AAO:0010016 AEO:0000072 BILA:0000072 CARO:0000072 Compound organ that contains one or more macroscopic anatomical spaces. EHDAA2:0003072 FMA:55671 HAO:0000072 TAO:0001490 TGMA:0001857 UBERON:0000489 VHOG:0001730 XAO:0003165 ZFA:0001490 cavitated organ this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future uberon embryo AAO:0011035 AEO:0000169 Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. BILA:0000056 BSA:0000039 BTO:0000379 CALOHA:TS-0229 EFO:0001367 EHDAA2:0000002 EHDAA2_RETIRED:0003236 EHDAA:38 EMAPA:16039 FBbt:00000052 FMA:69068 GAID:963 MAT:0000226 MESH:A16.254 MIAA:0000019 OGEM:000001 Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo OpenCyc:Mx4rwP1ceZwpEbGdrcN5Y29ycA UBERON:0000922 UMLS:C0013935 VHOG:0001766 XAO:0000113 ZFA:0000103 developing organism developmental tissue embryonic embryonic organism uberon stomach AAO:0000579 ANISEED:1235297 An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. BTO:0001307 CALOHA:TS-0980 EFO:0000837 EHDAA2:0001915 EHDAA:2993 EMAPA:17021 EV:0100070 FMA:7148 GAID:293 It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG] MA:0000353 MAT:0000051 MESH:A03.492.766 MIAA:0000051 OpenCyc:Mx4rvVjlqpwpEbGdrcN5Y29ycA Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO] TAO:0002121 UBERON:0000945 UMLS:C0038351 VHOG:0000408 Ventricular We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa XAO:0000128 anterior intestine galen:Stomach gaster mesenteron stomach chamber uberon ventriculus brain (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG] AAO:0010478 ABA:Brain BAMS:Br BAMS:Brain BILA:0000135 BTO:0000142 CALOHA:TS-0095 Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO] DHBA:10155 EFO:0000302 EHDAA2:0000183 EHDAA:2641 EHDAA:6485 EMAPA:16894 EV:0100164 FBbt:00005095 FMA:50801 GAID:571 HBA:4005 MA:0000168 MAT:0000098 MESH:A08.186.211 MIAA:0000098 OpenCyc:Mx4rvVjT65wpEbGdrcN5Y29ycA PBA:3999 Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO] TAO:0000008 The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO) UBERON:0000955 UMLS:C0006104 UMLS:C1269537 VHOG:0000157 XAO:0000010 ZFA:0000008 encephalon galen:Brain http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=21 requires review for applicability to invertebrate structures, e.g. synganglion suprasegmental levels of nervous system suprasegmental structures synganglion the brain uberon cornea AAO:0010344 BTO:0000286 CALOHA:TS-0171 Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman’s membrane in mammals. In fish, and aquatic vertebrates in general, the cornea plays no role in focusing light, since it has virtually the same refractive index as water EFO:0000377 EHDAA2:0000316 EHDAA:10199 EMAPA:17161 EV:0100341 FMA:58238 GAID:892 MA:0000266 MESH:A09.371.060.217 OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA TAO:0000640 UBERON:0000964 UMLS:C0010031 VHOG:0000164 XAO:0000180 ZFA:0000640 cornea of camera-type eye corneal the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure tunica cornea uberon eye An organ that detects light. BILA:0000017 BTO:0000439 CALOHA:TS-0309 EFO:0000827 EV:0100336 FBbt:00005162 GAID:69 MAT:0000140 MESH:A01.456.505.420 MIAA:0000140 Note that whilst this is classified as an organ, it is in fact more of a unit composed of different structures: in Drosophila, it includes the interommatidial bristle as a part; we consider here the vertebrate eye to include the eyeball/eye proper as a part, with the eye having as parts (when present): eyelids, conjuctiva, OpenCyc:Mx4rvViTvpwpEbGdrcN5Y29ycA This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each) UBERON:0000970 light-detecting organ ocular optic uberon visual apparatus pleura BTO:0001791 CALOHA:TS-2081 EFO:0001980 EMAPA:16775 EV:0100044 FMA:9583 GAID:360 In MA, is_a cavity lining. In FMA, is_a (viscous) serous membrane (which includes mesothelium plus connective tissue). Note the MA structure should probably be associated with the mesothelium of pleura in FMA. JB/EHDAA2 argues the term 'pleura' is best used for the mesothelial lining (thus excluding connective tissue). See http://purl.obolibrary.org/obo/uberon/tracker/86 MA:0000433 MESH:A04.716 OpenCyc:Mx4rv3zwLZwpEbGdrcN5Y29ycA The serous membrane that covers the lungs and lines the pleural cavity. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.264][VHOG] UBERON:0000977 UMLS:C0032225 VHOG:0000394 pleura pleural pleural tissue the serous membrane surrounding the lungs and lining the walls of the pleural cavity uberon wall of pleural sac gonad AAO:0000213 Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO] BILA:0000123 BSA:0000079 BTO:0000534 EMAPA:16857 EMAPA:17383 Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG] FBbt:00004858 FMA xref is a 'general anatomical term' FMA:18250 GAID:368 HAO:0000379 MA:0002420 MESH:A05.360.576 OpenCyc:Mx4rwQvdiZwpEbGdrcN5Y29ycA Reproductive organ that produces and releases eggs (ovary) or sperm (testis). TAO:0000413 The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO] UBERON:0000991 UMLS:C0018067 VHOG:0000397 WBbt:0005175 XAO:0003146 ZFA:0000413 gonada gonadal uberon female gonad (...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG] AAO:0000371 BILA:0000125 BSA:0000080 BTO:0000975 CALOHA:TS-0730 EFO:0000973 EHDAA2:0001360 EHDAA:8124 EMAPA:17962 EV:0100111 Either of paired female reproductive organs involved in production of ova and female sex hormones.[AAO] FBbt:00004865 FMA:7209 Female reproductive organ.[TAO] GAID:367 MA:0000384 MESH:A05.360.319.114.630 MIAA:0000125 OpenCyc:Mx4rvVi9QJwpEbGdrcN5Y29ycA Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous. Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity. Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct. Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo TAO:0000403 UBERON:0000992 UMLS:C0029939 VHOG:0000251 XAO:0000258 ZFA:0000403 female organism genitalia gonad female organism genitalia gonada female organism reproductive system gonad female organism reproductive system gonada female reproductive system gonad female reproductive system gonada genitalia of female organism gonad genitalia of female organism gonada gonad of female organism genitalia gonad of female organism reproductive system gonad of female reproductive system gonad of genitalia of female organism gonad of reproductive system of female organism gonada of female organism genitalia gonada of female organism reproductive system gonada of female reproductive system gonada of genitalia of female organism gonada of reproductive system of female organism ovarian ovaries ovarium ovary ovum-producing ovary reproductive system of female organism gonad reproductive system of female organism gonada the gonad of a female organism which contains germ cells uberon uterus An infundibulum, uterine tube, uterus, and vagina also differentiate along the oviducts of eutherian mammals.[well established][VHOG] BTO:0001424 CALOHA:TS-1102 EFO:0000975 EMAPA:29915 EV:0100113 FMA:17558 GAID:172 MA:0000389 MAT:0000127 MESH:A05.360.319.679 MIAA:0000127 Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle 'vagina' which functions as the birth canal. Marsupial embryos form a choriovitelline 'placenta' (which can be thought of as something between a monotreme egg and a 'true' placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream. OpenCyc:Mx4rvViojJwpEbGdrcN5Y29ycA The hollow muscular organ in female mammals in which the blastocyst normally becomes embedded and in which the developing embryo and fetus is nourished. Its cavity opens into the vagina below and into a uterine tube on either side. [TFD][VHOG] Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused [Wikipedia:Uterus] UBERON:0000995 UMLS:C0042149 VHOG:0001137 galen:Uterus the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth uberon uterine vagina 'The distal end of the oviducts differentiates as a vagina in Metatheria and Eutheria.' Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective, Third Edition (2001) Orlando Fla.: Harcourt College Publishers, p.688 A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]. BTO:0000243 CALOHA:TS-1103 EFO:0000976 EMAPA:18986 EV:0100117 FMA:19949 GAID:381 MA:0000394 MAT:0000128 MESH:A05.360.319.779 MIAA:0000128 OpenCyc:Mx4rvVj1B5wpEbGdrcN5Y29ycA Organ with organ cavity which connects the cervical canal of uterus to the vestibule of vagina.[FMA] The distal end of the oviducts differentiates as a vagina in Metatheria and Eutheria.[well established][VHOG] The genital canal in the female, leading from the opening of the vulva to the cervix of the uterus. [TFD][VHOG] UBERON:0000996 UMLS:C0042232 VHOG:0001138 distal oviductal region distal portion of oviduct galen:Vagina uberon vaginae vaginal mammalian vulva BTO:0003101 CALOHA:TS-1168 EFO:0000978 EV:0100118 FMA:20462 GAID:383 MA:0000395 MAT:0000169 MESH:A05.360.319.887 MIAA:0000169 OpenCyc:Mx4rvgAWeJwpEbGdrcN5Y29ycA The external genital organs of the female, including the labia majora, labia minora, clitoris, and vestibule of the vagina. [TFD][VHOG] UBERON:0000997 UMLS:C0042993 VHOG:0001458 external genital organs of the female mammal[WP]. female pudendum galen:Vulva mammalian vulva puboperineal region pudendum pudendum femininum pudendum femininum pudendum muliebre skin of female pudendum skin of vulva uberon vulva vulval nervous system A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] AAO:0000324 Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] BILA:0000079 BTO:0001484 CALOHA:TS-1313 EFO:0000802 EHDAA2:0001246 EHDAA:826 EMAPA:16469 EV:0100162 FBbt:00005093 FMA:7157 GAID:466 MA:0000016 MAT:0000026 MESH:A08 MIAA:0000026 Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] OpenCyc:Mx4rvViT_pwpEbGdrcN5Y29ycA TAO:0000396 The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. UBERON:0001016 UMLS:C0027763 VHOG:0000402 WBbt:0005735 XAO:0000177 ZFA:0000396 nerve net nervous neural neurological system systema nervosum uberon chordate pharynx (...) the earliest vertebrates possessed unjointed internal and external branchial arches, and musculature encircling the pharynx.[well established][VHOG] A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]. A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. AAO:0000967 Anatomical cavity bounded by the derivatives of the branchial arches.[AAO] BTO:0001049 CALOHA:TS-0785 Consider generalizing to deuterostome pharynx EFO:0000836 EHDAA2:0001458 EHDAA:2947 EMAPA:16706 EV:0100065 FMA:46688 GAID:155 MA/FMA pharynx not part of digestive/alimentary system, we are consistent with this scheme MA:0000432 MESH:A03.867 OpenCyc:Mx4rvViv7ZwpEbGdrcN5Y29ycA Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills. Kimmel et al, 1995.[TAO] Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills[ZFA:0000056, ZFIN:ZDB-PUB-961014-576]. TAO:0000056 The portion of the alimentary canal between the mouth and the oesophagus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] UBERON:0001042 UMLS:C0031354 VHOG:0000462 XAO:0003227 ZFA:0000056 galen:Pharynx pharynx relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: develops_from respiratory system (UBERON:0001004)[AAO] relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: part_of respiratory system (UBERON:0001004)[AAO] uberon esophagus AAO:0000145 ANISEED:1235301 Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO] BTO:0000959 CALOHA:TS-0700 EFO:0000835 EHDAA2:0001285 EHDAA:2937 EMAPA:16833 EV:0100069 FMA:7131 GAID:291 MA:0000352 MAT:0000048 MESH:A03.365 MIAA:0000048 OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA TAO:0000204 The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG] Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). UBERON:0001043 UMLS:C0014876 VHOG:0000450 XAO:0000127 ZFA:0000204 esophageal esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995) galen:Esophagus gullet oesophagus uberon rectum AAO:0010401 BTO:0001158 CALOHA:TS-1180 EFO:0000848 EHDAA2:0001592 EHDAA:5836 EMAPA:17896 EV:0100081 FMA:14544 GAID:311 In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html MA:0000336 MAT:0000050 MESH:A03.492.411.495.767 MIAA:0000050 OpenCyc:Mx4rvVjaU5wpEbGdrcN5Y29ycA The terminal portion of the large intestine between the ileo-pelvic colon and the anus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG] UBERON:0001052 UMLS:C0034896 VHOG:0001751 XAO:0000238 galen:Rectum intestinum rectum rectal rectal sac terminal portion of intestine terminal portion of large intestine the terminal portion of the intestinal tube, terminating with the anus uberon anatomical entity AAO:0010841 AEO:0000000 BILA:0000000 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. CARO:0000000 EHDAA2:0002229 FBbt:10000000 FBbt_root:00000000 FMA:62955 HAO:0000000 MA:0000001 TAO:0100000 TGMA:0001822 UBERON:0001062 UMLS:C1515976 XAO:0000000 ZFA:0100000 uberon ileocecal junction A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice FMA:11338 MA:0000332 UBERON:0001073 ileocaecal junction uberon caecum A cecum is present in most amniote species, and also in lungfish, but not in any living species of amphibian. In reptiles, it is usually a single median structure, arising from the dorsal side of the large intestine. Birds typically have two paired ceca, as, unlike other mammals, do hyraxes. Most mammalian herbivores have a relatively large cecum, hosting a large number of bacteria, which aid in the enzymatic breakdown of plant materials such as cellulose; in many species, it is considerably wider than the colon. In contrast, obligatory carnivores, whose diets contain little or no plant material, have a reduced cecum, which is often partially or wholly replaced by the vermiform appendix. Many fish have a number of small outpocketings, called pyloric ceca, along their intestine; despite the name they are not homologous with the cecum of amniotes, and their purpose is to increase the overall area of the digestive epithelium.[2] Some invertebrates, such as squid,[3] may also have structures with the same name, but these have no relationship with those of vertebrates. A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction. BTO:0000166 CALOHA:TS-0122 EFO:0000850 EHDAA2:0000206 EHDAA:3913 EMAPA:35197 EV:0100397 FMA:14541 GAID:307 Kardong: in some herbivorous lizards, a cecum is present between small and large intestines MA:0000334 MESH:A03.492.411.495.209 MIAA:0000288 OpenCyc:Mx4rve6u4JwpEbGdrcN5Y29ycA UBERON:0001153 UMLS:C0007531 VHOG:0001559 blind intestine blindgut caeca caecal caecum ceca cecum galen:Cecum intestinum caecum intestinum crassum caecum intestinum crassum cecum uberon colon AAO:0010400 Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG] BTO:0000269 CALOHA:TS-0158 EFO:0000361 EMAPA:18939 EV:0100079 FMA:14543 GAID:309 In mammals, the colon consists of four sections: the ascending colon, the transverse colon, the descending colon, and the sigmoid colon[WP] In zebrafish, the posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates[ZFIN] Last portion of the large intestine before it becomes the rectum. MA:0000335 MAP:0000001 MAT:0000526 MESH:A03.492.411.495.356 OpenCyc:Mx4rvgLEM5wpEbGdrcN5Y29ycA TAO:0000706 TODO - abstract this such that it legitimately covers all vertebrates The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.[AAO] The posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates. Wallace et al, 2005.[TAO] UBERON:0001155 UMLS:C0009368 VHOG:0000648 XAO:0000243 ZFA:0000706 colonic galen:Colon hindgut it extracts water and salt from solid wastes before they are eliminated from the body[WP] large bowel posterior intestine uberon right ureter An ureter that is part of a right side of organism [Automatically generated definition]. FMA:15571 MA:0001685 This class was created automatically from a combination of ontologies UBERON:0001222 UMLS:C0227682 https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern uberon urinary bladder A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] AAO:0000623 Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO] BTO:0001418 CALOHA:TS-1090 EFO:0000290 EHDAA2:0000174 EHDAA:9328 EMAPA:18321 EV:0100098 FMA:15900 GAID:0000004 In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG] MA:0000380 MAT:0000122 MESH:A05.810.161 MIAA:0000122 OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA UBERON:0001255 UMLS:C0005682 VHOG:0000740 XAO:0000154 bladder distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. galen:UrinaryBladder uberon urocyst vesica vesica urinaria vesical pancreas AAO:0010112 An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. As a secretory organ serving exocrine and endocrine functions, the pancreas is specific to the vertebrates[PMID:16417468] Hagfishes and lampreys are unique in the complete separation of their endocrine pancreas (islet or- gan) and their exocrine pancreas (50). The endocrine and exocrine pancreas are coassociated in crown gnathostomes (50). In Branchiostoma and Ciona, there is no diverticulum as there is in hagfishes, lampreys, and gnathostomes, only dispersed insulin-secreting cells in the walls of the gastrointestinal tract (51, 52) BTO:0000988 CALOHA:TS-0736 EFO:0000855 EHDAA2:0001367 EHDAA:6893 EMAPA:17503 EV:0100092 FMA:7198 GAID:334 In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG] MA:0000120 MAT:0000075 MESH:A03.734 MIAA:0000075 OpenCyc:Mx4rvVimZZwpEbGdrcN5Y29ycA Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO] TAO:0000140 The mature pancreas of higher vertebrates and mammals comprises two major functional units: the exocrine pancreas, which is responsible for the production of digestive enzymes to be secreted into the gut lumen, and the endocrine pancreas, which has its role in the synthesis of several hormones with key regulatory functions in food uptake and metabolism. The exocrine portion constitutes the majority of the mass of the pancreas, and contains only two different cell types, the secretory acinar cells and the ductular cells. The endocrine portion, which comprises only 1–2% of the total mass, contains five different cell types, which are organized into mixed functional assemblies referred to as the islets of Langerhans The zebrafish does not have a discrete pancreas. Exocrine pancreatic tissue can be found scattered along the intestinal tract. The acinar structure of the exocrine pancreas is very similar to that of mammals and comprises cells with a very dark, basophilic cytoplasm UBERON:0001264 UMLS:C0030274 VHOG:0000050 XAO:0000136 ZFA:0000140 galen:Pancreas pancreatic uberon acetabular part of hip bone AAO:0000770 Cavity for the articulation of the proximal bone of the hind limb.[AAO] During the transformation from the osteolepiform fins to tetrapod limbs, the appendages and girdles underwent a number of radical changes. The pelvic girdle became a weight-bearing structure by evolution of an ischium, a full mesio-ventral contact between the two sides of the girdle, an ilium, and a contact between the vertebral column and the girdle through a sacral rib. Fore- and hindlimbs shifted laterally by reorientation of the glenoid and the acetabulum.[well established][VHOG] EHDAA:10661 EMAPA:18346 FMA:16579 GAID:206 In reptiles and in birds, the acetabula are deep sockets. MA:0001335 MESH:A02.835.232.611.108 OpenCyc:Mx4rwJlP9ZwpEbGdrcN5Y29ycA RETIRED_EHDAA2:0001427 The acetabulum is a concave surface of the pelvis. The head of the femur meets with the pelvis at the acetabulum, forming the hip joint. There are three bones of the os coxae (hip bone) that come together to form the acetabulum. Contributing a little more than two-fifths of the structure is the ischium, which provides lower and side boundaries to the acetabulum. The ilium forms the upper boundary, providing a little less than two-fifths of the structure of the acetabulum. The rest is formed by the pubis, near the midline. It is bounded by a prominent uneven rim, which is thick and strong above, and serves for the attachment of the acetabular labrum, which reduces its opening, and deepens the surface for formation of the hip joint. At the lower part of the acetabulum is the acetabular notch, which is continuous with a circular depression, the acetabular fossa, at the bottom of the cavity of the acetabulum. The rest of the acetabulum is formed by a curved, crescent-moon shaped surface, the lunate surface, where the joint is made with the head of the femur. Its counterpart in the pectoral girdle is the glenoid fossa.[WP,unvetted]. UBERON:0001269 UMLS:C0000962 VHOG:0000974 acetabular region acetabulum uberon whilst WP defines this as a surface, MA treats it as a bone. There are other FMA classes that may be better suited to representing the surface. endometrium Animals that have estrous cycles reabsorb the endometrium if conception does not occur during that cycle. Animals that have menstrual cycles shed the endometrium through menstruation instead BTO:0001422 CALOHA:TS-0276 EFO:0000980 EMAPA:29917 EV:0100115 FMA:17742 GAID:377 MA:0000390 MAT:0000319 MESH:A05.360.319.679.490 MIAA:0000319 The maternal part of the placenta (of eutherian mammals) is the vascularized and glandular uterine lining, or endometrium.[well established][VHOG] The mucous membrane lining the uterus. [TFD][VHOG] UBERON:0001295 UMLS:C0014180 VHOG:0001285 endometrial in FMA this is subdivided into basal and outer the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy tunica mucosa (endometrium) tunica mucosa uteri uberon uterine endometrium uterine mucosa uterine mucous membrane bone element AAO:0000047 AEO:0000082 Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO] BTO:0000140 CALOHA:TS-0088 EFO:0000298 EHDAA2:0003082 EMAPA:32782 ENVO:00002039 EV:0100140 FMA:30317 FMA:5018 GAID:92 MA:0001459 MAT:0000299 MIAA:0000299 OpenCyc:Mx4rvViDlpwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVkCG5wpEbGdrcN5Y29ycA Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system.[TAO] Skeletal element that is composed of bone tissue. Skeletal element that is composed of bone tissue.[VSAO] TAO:0001514 The 'new animal phylogeny' reveals that many of the groups known to biomineralize sit among close relatives that do not, and it favours an interpretation of convergent or parallel evolution for biomineralization in animals. (...) Whether this 'biomineralization toolkit'of genes reflects a parallel co-option of a common suite of genes or the inheritance of a skeletogenic gene regulatory network from a biomineralizing common ancestor remains an open debate.[debated][VHOG] UBERON:0001474 UMLS:C0262950 VHOG:0001190 VSAO:0000057 XAO:0000169 ZFA:0001514 bone bone element bone organ galen:Bone relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] uberon vein AAO:0010212 AEO:0000209 Any of the tubular branching vessels that carry blood from the capillaries toward the heart. BTO:0000234 CALOHA:TS-1108 EFO:0000816 EHDAA2:0003254 EMAPA:35906 EV:0100031 FMA:50723 GAID:492 MA:0000067 MAT:0000037 MESH:A07.231.908 MIAA:0000037 OpenCyc:Mx4rvVjkWpwpEbGdrcN5Y29ycA Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO] TAO:0000082 TODO - check with MA - vein vs venous blood vessel The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG] UBERON:0001638 UMLS:C0042449 VHOG:0001743 XAO:0000115 ZFA:0000082 galen:Vein uberon vascular element vena venae venous subtree venous tree organ part venous vessel supraorbital vein FMA:50904 MA:0002228 The supraorbital vein begins on the forehead where it communicates with the frontal branch of the superficial temporal vein. It runs downward superficial to the Frontalis muscle, and joins the frontal vein at the medial angle of the orbit to form the angular vein. Previous to its junction with the frontal vein, it sends through the supraorbital notch into the orbit a branch which communicates with the ophthalmic vein; as this vessel passes through the notch, it receives the frontal diploic vein through a foramen at the bottom of the notch. The areas drained by this vessel are the forehead, eyebrow and upper eyelid. [WP,unvetted]. This class was created automatically from a combination of ontologies UBERON:0001654 UMLS:C0226535 supra-orbital vein uberon tongue A mobile mass of muscular tissue that is covered with mucous membrane, occupies much of the cavity of the mouth, forms part of its floor, bears the organ of taste, and assists in chewing and swallowing. [TFD][VHOG] A muscular organ in the floor of the mouth. AAO:0010360 BTO:0001385 CALOHA:TS-1050 EFO:0000833 EHDAA2:0002062 EHDAA:9144 EMAPA:17185 EV:0100058 FMA:54640 GAID:816 MA:0000347 MAT:0000040 MESH:A14.549.885 MIAA:0000040 Many species of fish have small folds at the base of their mouths that might informally be called tongues, but they lack a muscular structure like the true tongues found in most tetrapods Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG] Muscular organ in the floor of the mouth.[FEED] OpenCyc:Mx4rvVjmJ5wpEbGdrcN5Y29ycA_53KXLq9EdqAAAACs6hnmQ TAO:0005333 The tongue has contributions from all pharyngeal arches which changes with time. The tongue initially begins as swelling rostral to foramen cecum, the median tongue bud.. tongue muscles derive from the somites - http://php.med.unsw.edu.au/embryology/index.php?title=Tongue_Development#Pharyngeal_Arch_Contributions The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech[GO][GO:0043586]. UBERON:0001723 UMLS:C0040408 VHOG:0000419 XAO:0000446 ZFA:0005333 glossal glossus in MA the tongue is part of the oral region, which in uberon is treated as the oral opening. consider revising oral opening - oral region equivalence. lingual uberon larynx (In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG] AAO:0000268 An anatomical cluster consisting of the epiglottus, the arytenoid cartilages, the thyroid cartilage, the cricoid cartilage and the muscles, membranes, and ligaments connecting them, and also of the mucosal covering these structures.[FEED] Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located.[AAO] BTO:0001208 CALOHA:TS-0532 EFO:0000838 EHDAA2:0004063 EMAPA:18333 EV:0100039 FMA:55097 GAID:108 Heterogeneous cluster that connects the pharynx to the tracheobronchial tree[FMA]. Kehlkopf@ge MA:0000414 MAT:0000187 MESH:A04.329 MIAA:0000187 OpenCyc:Mx4rvViOnZwpEbGdrcN5Y29ycA This class was created automatically from a combination of ontologies UBERON:0001737 UMLS:C0023078 VHOG:0001279 XAO:0003081 galen:Larynx laryngeal uberon lymphoid tissue BTO:0000753 CALOHA:TS-0584 FMA:55220 GAID:342 MA:0002436 MESH:A10.549 Portion of connective tissue with various types of white blood cells enmeshed in it, most numerous being the lymphocytes[WP]. UBERON:0001744 UMLS:C0024296 galen:LymphoidTissue lymphatic tissue lymphocytic tissue uberon gingiva BTO:0000519 CALOHA:TS-2074 EFO:0001925 EMAPA:35945 EV:0100064 FMA has a 3-level breakdown of jaws into: region, jaw (skeleton+gums), skeleton. FMA:59762 GAID:1257 MA:0000342 MESH:A14.254.646.480 OpenCyc:Mx4rvViWnZwpEbGdrcN5Y29ycA The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]. UBERON:0001828 UMLS:C0017562 VHOG:0001269 galen:Gingiva gingival gingival mucosa gum gum tissue gums uberon mammary gland A mouse mammary gland contains a single duct or sinus, forming 5-10 secondary ducts A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males. Any of the milk-producing apocrine glands typically occurring in pairs in female mammals and consisting of lobes containing clusters of alveoli with a system of ducts to convey the milk to an external nipple or teat. [TFD][VHOG] BTO:0000817 Brustdruese CALOHA:TS-0595 EFO:0000854 EMAPA:17759 EV:0100125 MA:0000145 MAT:0000073 MESH:A10.336.482 MIAA:0000073 OpenCyc:Mx4rvVjVq5wpEbGdrcN5Y29ycA Originally this was classified as a female reproductive structure, as it was in the MP in 2011 The BTO class represents the combination of nipple plus lobe The FMA class represents an individule lobe. The nipple is not a part The MA class represents a composite structure, including the nipple, fat, connective tissue, smooth muscle as parts The detailed similarities of mammary glands in living monotremes, marsupials, and eutherians argue for a monophyletic origin of these glands, perhaps by the combination of parts of preexisting sebaceous and sweat glands.[well established][VHOG] The male Dayak fruit bat has lactating mammary glands The mammary glands of humans are in the thoracid/breast region. In other mammals they may be located elsewhere on the mammary ridges. UBERON:0001911 UMLS:C0929301 VHOG:0000398 dug glandula mammaria glandula mammaria lactiferous gland lobe of breast lobe of mammary gland mamma mammae mammary milk patch uberon blood vessel A vessel through which blood circulates in the body. AAO:0011004 AEO:0000207 Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG] Any of the vessels through which blood circulates in the body.[AAO] BTO:0001102 CALOHA:TS-0080 EFO:0000817 EHDAA2:0003252 EHDAA:240 EMAPA:32743 EMAPA:35993 FMA:50722 FMA:63183 FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX GAID:169 MA:0000060 MAT:0000393 MESH:A07.231 OpenCyc:Mx4rvVjxlpwpEbGdrcN5Y29ycA TAO:0002137 The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG] UBERON:0001981 UMLS:C0005847 VHOG:0001250 XAO:0001011 ZFA:0005314 annelids have blood vessels, but this class is not applicable to annelids. consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus region of vascular tree organ uberon vas sanguineum vascular element vascular tree organ region placenta BTO:0001078 CALOHA:TS-0799 EFO:0001407 EMAPA:35689 EV:0100119 Eutherians: In eutherians, the chorioallantoic membrane of the fetus establishes intimate contact with the adjacent vascular wall of the mother's uterus to produce the placenta, a composite structure formed in part from tissues of the fetus and in part from tissues of the mother [ISBN10:0073040584 (Vertebrates, Kardong)]. TODO - is taxon restriction too strict, even if we restrict def to allantoic placenta? - WP says: also found in some snakes and lizards with varying levels of development up to mammalian levels. Pough et al. 1992. Herpetology: Third Edition. Pearson Prentice Hall:Pearson Education, Inc., 2002. // See also: http://dx.doi.org/10.1002/jmor.11011 FMA:63934 GAID:379 MA:0000386 MAT:0000279 MESH:A16.759 MIAA:0000279 Marsupials possess only a rudimentary placenta, with reduced nutrient and oxygen exchanging capabilities. OpenCyc:Mx4rvv4zZ5wpEbGdrcN5Y29ycA Phylogenetic analyses of the concatenated data set using maximum parsimony, maximum likelihood and distance based (neighbour joining) methods all converged on a nearly identical, well supported topology defining four principal eutherian lineages. The results affirm monophyly of traditional placental orders (except Artiodactyla and Insectivora), and also support some previously proposed, as well as new, superordinal clades.[well established][VHOG] UBERON:0001987 UMLS:C0032043 VHOG:0001266 allantoic placenta eutherian placenta organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. placental uberon thyroid gland (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (2) a groove in the pharyngeal floor known as the endostyle, or a thyroid gland derived from part of the endostyle (...).[well established][VHOG] A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. AAO:0010544 BTO:0001379 CALOHA:TS-1047 EFO:0000861 EHDAA2:0002028 EHDAA:2148 EHDAA:2975 EMAPA:17068 EV:0100133 Either of paired structures located in the throat which develop from the ventral wall of the pharynx and excretes hormones involved in the morphological and functional changes during metamorphosis as well as influencing other tissues.[AAO] FMA:9603 GAID:465 In fish, it is usually located below the gills and is not always divided into distinct lobes. However, in some teleosts, patches of thyroid tissue are found elsewhere in the body, associated with the kidneys, spleen, heart, or eyes In larval lampreys, the thyroid originates as an exocrine gland, secreting its hormones into the gut, and associated with the larva's filter-feeding apparatus. In the adult lamprey, the gland separates from the gut, and becomes endocrine, but this path of development may reflect the evolutionary origin of the thyroid. For instance, the closest living relatives of vertebrates, the tunicates and Amphioxus, have a structure very similar to that of larval lampreys, and this also secretes iodine-containing compounds (albeit not thyroxine) In tetrapods, the thyroid is always found somewhere in the neck region. In most tetrapod species, there are two paired thyroid glands - that is, the right and left lobes are not joined together. However, there is only ever a single thyroid gland in most mammals, and the shape found in humans is common to many other species MA:0000129 MAT:0000081 MESH:A06.407.900 MIAA:0000081 OpenCyc:Mx4rvVjLT5wpEbGdrcN5Y29ycA UBERON:0002046 UMLS:C0040132 VHOG:0000418 XAO:0000162 galen:ThyroidGland glandula thyroidea thyroid uberon viscus AAO:0010386 An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper.[AAO] An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. BTO:0001491 EHDAA:512 EMAPA:16245 FMA:7085 MA:0000019 MESH:A01.960 Organsystem@ge RETIRED_EHDAA2:0002201 UBERON:0002075 UMLS:C0042779 XAO:0003034 general anatomical term in FMA. Note that we place the MA class here temporarily, although properly systems should be distinguished from organs splanchnic tissue uberon viscera visceral organ visceral organ system visceral tissue spleen AAO:0010395 An organ involved in red blood cell filtration and immune response.[AAO] BTO:0001281 CALOHA:TS-0956 EFO:0000869 EMAPA:18767 EV:0100055 FMA:7196 GAID:1289 In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells MA:0000141 MAT:0000085 MESH:A15.382.520.604.713 MIAA:0000085 Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA TAO:0000436 UBERON:0002106 UMLS:C0037993 VHOG:0000120 With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] XAO:0000328 ZFA:0000436 galen:Spleen lien lienal splenic the organ that functions to filter blood and to store red corpuscles and platelets uberon liver AAO:0010111 All vertebrates possess a liver (reference 1); Later in craniate evolution, an anterior gill arch was transformed into jaws, and many new types of feeding subsequently evolved.(...) A liver evolved that, among its many functions, stores considerable energy as glycogen or lipid (reference 2).[well established][VHOG] An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. The zebrafish liver differs from the mammalian liver in that the hepatocytes are not clearly organized in cords or lobules and the typical portal triads are not apparent. In addition, the zebrafish liver does not have Kuppfer cells. Furthermore, a clear distinction can be made between the male and female liver in the adult zebrafish. The female hepatocytes are very basophilic (Figure 15c) as a result of the production of vitellogenin (Van der Ven et al. 2003). BTO:0000759 CALOHA:TS-0564 EFO:0000887 EHDAA2:0000997 EHDAA:2197 EMAPA:16846 EV:0100089 FMA:7197 GAID:288 MA:0000358 MAT:0000097 MESH:A03.620 MIAA:0000097 Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function. OpenCyc:Mx4rvVimppwpEbGdrcN5Y29ycA Organ which secretes bile and participates in formation of certain blood proteins.[AAO] TAO:0000123 The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates. UBERON:0002107 UMLS:C0023884 VHOG:0000257 XAO:0000133 ZFA:0000123 galen:Liver hepatic iecur jecur relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO] secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. uberon kidney A paired organ of the urinary tract which has the production of urine as its primary function. AAO:0000250 BTO:0000671 CALOHA:TS-0510 EFO:0000929 EMAPA:17373 EV:0100096 FMA:7203 GAID:423 MA:0000368 MAT:0000119 MESH:A05.810.453 MIAA:0000119 One of either of a pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.[AAO] OpenCyc:Mx4rvVjlYpwpEbGdrcN5Y29ycA UBERON:0002113 UMLS:C0022646 XAO:0003267 galen:Kidney renal reniculate kidney uberon exocrine gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas AEO:0000097 BTO:0000765 CALOHA:TS-2012 Currently this is logically defined by the system it belongs to, but a better system may be base this on presence/absence of ducts. However, the dual nature of the liver should be taken into consideration here. Consider adding subclasses EHDAA2:0003097 EMAPA:35327 FMA:9596 GAID:34 MA:0002564 MESH:A10.336 UBERON:0002365 UMLS:C0015282 ducted gland glandula exocrina uberon prostate gland BTO:0001129 CALOHA:TS-0828 EFO:0000858 EMAPA:19287 EV:0100104 FMA:9600 GAID:392 MA:0000404 MAT:0000078 MESH:A05.360.444.575 MIAA:0000078 OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA TODO - FMA treats the gland as part of the prostate - see also FMA:74119. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. UBERON:0002367 UMLS:C0033572 VHOG:0001261 galen:ProstateGland male prostate prostata prostate prostatic uberon endocrine gland AEO:0000098 BTO:0001488 CALOHA:TS-1300 EHDAA2:0003098 EMAPA:35999 Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. FMA:9602 GAID:335 MA:0002563 MESH:A06.407 OpenCyc:Mx4rvbkiRZwpEbGdrcN5Y29ycA UBERON:0002368 UMLS:C0014133 ductless gland ductless gland glandula endocrina glandulae endocrinae uberon adrenal gland AAO:0010551 All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG] Anatomical structure which is found on the surface of the kidney and secretes various hormones including epinephrine, norephinephrine, aldosterone, corticosterone, and cortisol.[AAO] BTO:0000047 CALOHA:TS-0016 EFO:0000238 EMAPA:18426 EV:0100135 Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]. FMA:9604 GAID:446 MA:0000116 MAT:0000071 MESH:A06.407.071 MIAA:0000071 OpenCyc:Mx4rvXYiz5wpEbGdrcN5Y29ycA The origin of the adrenal gland is still controversial. It is thought to share the same origin as the kidney and gonads, derived from coelomic epithelium of the urogenital ridge and/or the underlying mesenchyme (Keegan and Hammer, 2002; Morohashi, 1997). We follow Kardong and state homology at the level of the cortex and medulla rather than gland as a whole UBERON:0002369 UMLS:C0001625 VHOG:0001141 XAO:0000164 adrenal adrenal capsule adrenal medulla cell atrabiliary capsule epinephric gland epinephros galen:AdrenalGland glandula adrenalis glandula suprarenalis glandula suprarenalis interrenal gland suprarenal capsule suprarenal cortex manufactures corticosteroids; suprarenal medulla manufactures epinephrine and norepinephrine; suprarenal medulla receives preganglionic sympathetic innervation from the greater thoracic splanchnic n. suprarenal gland uberon bone marrow AAO:0011007 BTO:0000141 BTO:0000829 CALOHA:TS-0087 EFO:0000868 EMAPA:32760 EV:0100046 FMA:9608 GAID:1287 In adults, marrow in large bones produces new blood cells[Wikipedia:Bone_marrow] MA:0000134 MAT:0000084 MESH:A15.382.216 MIAA:0000084 OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG] UBERON:0002371 UMLS:C0005953 VHOG:0001218 XAO:0000123 galen:BoneMarrow medulla of bone medulla ossea medulla ossium the soft tissue that fills the cavities of bones uberon tonsil BTO:0001387 CALOHA:TS-1053 EFO:0001401 EMAPA:35871 EV:0100052 FMA:9609 GAID:341 MA:0000143 MESH:A03.867.603.925 Mandel OpenCyc:Mx4rvVivrZwpEbGdrcN5Y29ycA UBERON:0002372 UMLS:C0836921 UMLS:C1519547 UMLS:C1519548 VHOG:0001139 either of the two small almond-shaped masses of lymph tissue found on either side of the oropharynx the term 'tonsil' can be ambiguous, sometimes refering specifically to the palatine tonsil, sometimes generically to include the cecal tonsils of avians. This class represents lymphoid tissue that is part of the tonsillar ring, in the mouth/throat region uberon round window of inner ear EMAPA:19239 FMA:56932 GAID:878 MA:0002814 MESH:A09.246.631.246.814 UBERON:0002502 cochlear window fenestra cochleae fenestra rotunda round window round window of petrous part of temporal bone the opening on the medial wall of the middle ear leading into the cochlea, closed in life by the secondary tympanic membrane; serves to regulate fluid pressure in the inner ear uberon gland AAO:0000212 AEO:0000096 BTO:0000522 Druese EFO:0000797 EHDAA2:0003096 EHDAA:2161 EHDAA:4475 EHDAA:6522 EMAPA:18425 FBbt:00100317 FMA:7146 FMA:86294 HAO:0000375 MA:0003038 MAT:0000021 MIAA:0000021 OpenCyc:Mx4rwP3vyJwpEbGdrcN5Y29ycA UBERON:0002530 UBERON:MIAA_0000021 UMLS:C1285092 WikipediaCategory:Glands an organ that functions as a secretory or excretory organ galen:Gland glandula glandular glandular organ uberon paired fin Fin that is one of a pair located ventrally on the organism. TAO:0002278 UBERON:0002534 VSAO:0000111 ZFA:0005596 artioptérygie@fr nageoire paire@fr pelvic/pectoral fin uberon surface structure AAO:0010337 AEO_RETIRED:0000010 Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. EHDAA2_RETIRED:0003010 Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA] TAO:0000292 UBERON:0003102 VSAO:0000001 XAO:0003028 ZFA:0000292 anatomical surface feature galen:SurfaceRegion surface feature surface region uberon compound organ AAO:0010015 AEO:0000024 Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. BILA:0000024 CARO:0000024 EHDAA2:0003024 HAO:0000024 TADS:0000598 TAO:0000496 TGMA:0001837 UBERON:0003103 VHOG:0001723 XAO:0003041 ZFA:0000496 organ this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs uberon reproductive organ An organ involved in reproduction EMAPA:17381 GO uses genitalia for the singular organ MA:0001752 MESH:A05.360 OpenCyc:Mx4rwO39aJwpEbGdrcN5Y29ycA TGMA:0000591 UBERON:0003133 UMLS:C0017420 WBbt:0008422 genital organ genitalia reproductive system organ sex organ uberon mouth mucosa A mucous membrane that lines the mouth. BTO:0002860 CALOHA:TS-0716 EMAPA:26937 FMA:59660 GAID:951 MA:0002794 MESH:A10.615.550.599 UBERON:0003729 UMLS:C0026639 buccal mucosa mouth mucosa mouth mucous membrane mouth organ mucosa mucosa of mouth mucosal lining of mouth mucous membrane of mouth oral mucosa oral mucous membrane oral part of viscerocranial mucosa the mucous membrane epithelium of the mouth. It can be divided into three categories: masticatory, lining, and specialized[Wikipedia:Oral_mucosa]. this is defined as any mucous membrane of the mouth - including palate, lips, uvula, etc. ncit split mouth/oral mucosa into lip and buccal. In future we may split into masticatory/keratinized (gingiva + hard palate) vs lining/non-keratinized (lips, cheeks, floor of mouth, soft palate). FMA distinguishes between mucosa of mouth and region of mouth (the latter including the buccal mucosa) tunica mucosa oris tunica mucosa oris uberon sex gland Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. MA:0001751 UBERON:0003937 genitalia gland gland of genitalia gland of reproductive system reproductive gland reproductive system gland uberon anatomical conduit AEO:0000080 Any tube, opening or passage that connects two distinct anatomical spaces. EHDAA2:0003080 FMA has both conduit and conduit space. In EHDAA2 this is a surface feature FMA:242873 UBERON:0004111 foramen foramina opening ostia ostium uberon endoderm-derived structure An anatomical structure that develops (entirely or partially) from the endoderm. Grouping term for query purposes UBERON:0004119 uberon mesoderm-derived structure An anatomical structure that develops (entirely or partially) from the mesoderm. Grouping term for query purposes UBERON:0004120 uberon ectoderm-derived structure An anatomical structure that develops (entirely or partially) from the ectoderm. Grouping term for query purposes UBERON:0004121 uberon hemopoietic organ BTO:0004605 FMA:7143 MA:0000747 Organ that is part of the hematopoietic system. UBERON:0004177 consider splitting out lymph organ, compare with lymph node haematological system organ haemopoietic system organ hematopoeitic or lymphoid organ hematopoeitic organ hematopoietic system organ lymph organ lymphoid organ organ of haematological system organ of haemopoietic system organ of hematopoietic system organ of organa haemopoietica organa haemopoietica organ the FMA class 'lymphoid organ' is a general anatomical term the organs in which the formed elements of the blood and lymph are produced[http://encyclopedia2.thefreedictionary.com/Hematopoietic+Organs]. uberon endodermal part of digestive tract A portions of the gut that is derived from endoderm. EMAPA:32930 UBERON:0004185 endodermal gut gut endoderm uberon comma-shaped body CSB EMAPA:27681 EMAPA:27835 The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron UBERON:0004198 ZFA:0005588 uberon cavity lining MA:0002448 UBERON:0004457 consider merging with serous membrane in MA this groups pericardium, pleura and periotoneal cavity lining uberon paired limb/fin An appendage that is part of a appendage girdle complex. UBERON:0004708 UBERON:0009872 VSAO:0000067 girdle-associated appendage jointed paired lateral appendage limb or fin limb/fin paired appendage pectoral or pelvic appendage pelvic/pectoral appendage this class is the union of the classes limb, pectoral fin and pelvic fin. uberon skeletal element AAO:0011129 Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] TAO:0001890 UBERON:0004765 VSAO:0000128 XAO:0004012 ZFA:0005494 galen:SkeletalStructure uberon ectodermal part of digestive tract A portion of the gut that is derived from ectoderm. UBERON:0004906 ectodermal gut gut ectoderm uberon subdivision of digestive tract A proximal-distal subdivision of the digestive tract. FBbt:00100315 FMA:71131 UBERON:0004921 alimentary system subdivision intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct. intestinal tract segment of intestinal tract subdivision of alimentary system uberon organ component layer A part of a wall of an organ that forms a layer. FMA:82485 UBERON:0004923 uberon immune organ An organ that is part of a immune system [Automatically generated definition]. UBERON:0005057 immune system organ uberon reproductive structure An anatomical structure that is part of the reproductive system. UBERON:0005156 reproductive system structure uberon multi cell part structure A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. AAO:0011000 CARO:0001000 FBbt:00007060 FMA:83115 UBERON:0005162 cell part cluster multi-cell-component structure multi-cell-part structure uberon we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.' abdomen element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. MA:0000522 UBERON:0005172 abdomen organ uberon abdominal segment element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. MA:0000529 UBERON:0005173 abdominal segment organ uberon trunk region element An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. MA:0000516 UBERON:0005177 trunk organ uberon thoracic segment organ An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. MA:0000563 UBERON:0005181 uberon upper body organ developing anatomical structure AEO:0000125 CALOHA:TS-2122 EHDAA2:0003125 FBbt:00007006 MIAA:0000019 UBERON:0005423 developing structure developmental structure developmental tissue uberon zone of bone organ FMA:10483 UBERON:0005913 bone organ zone uberon excretory tube A tube that is part of a excretory system. UBERON:0006555 uberon adrenal/interrenal gland All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG] This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells[GO] UBERON:0006858 VHOG:0001141 adrenal - interrenal gland adrenal gland - interrenal gland adrenal gland/interrenal tissue keep this grouping class so long as it is required for GO suprarenal gland - interrenal gland uberon digestive gland A gland, such as the liver or pancreas, that secretes into the alimentary canal substances necessary for digestion. AAO:0000130 BTO:0000345 UBERON:0006925 digestive system gland uberon digestive tract diverticulum Branch or outpocketing of the digestive tract. FBbt:00100316 UBERON:0009854 diverticulum of gut intestinal pouch uberon sac UBERON:0009856 diverticulum galen:Diverticulum pouch uberon multicellular anatomical structure An anatomical structure that has more than one cell as a part. CARO:0010000 FBbt:00100313 UBERON:0010000 multicellular structure uberon neural crest-derived structure An anatomical structure that develops from the neural crest. Grouping term for query purposes UBERON:0010313 uberon structure with developmental contribution from neural crest An anatomical structure that has some part that develops from the neural crest. Grouping term for query purposes UBERON:0010314 uberon central nervous system cell part cluster A multi cell part structure that is part of a central nervous system. FMA:83143 UBERON:0011215 cell part cluster of neuraxis neuraxis layer uberon organ system subdivision Anatomical structure, which consists of a specific set of the members of (predominantly) one organ or organ part subclass interconnected by zones of continuity or body substances; is demarcated from other subdivisions of the same organ system by one or more zones of continuity or anatomical lines; together with other subdivisions of the same organ system, it constitutes an organ system. Examples: rib cage, facial skeleton, portal system, central nervous system, upper respiratory tract, muscle group of back. FBbt:00007330 FMA:67509 UBERON:0011216 uberon epithelium-associated lymphoid tissue FMA:62811 UBERON:0012069 uberon hemopoietic tissue Blood-forming tissue, consisting of reticular fibers and cells. Also known as hemopoietic tissue Bone marrow in humans, kidney interstitium in Danio, within a stroma of reticuloendothelial tissue CALOHA:TS-2142 FMA:14073 UBERON:0012429 UMLS:C0229619 bone marrow tissue haemopoietic tissue hematopoietic tissue textus haemopoieticus uberon subdivision of uterine tube FMA class may only represent the uterine portion FMA:18302 UBERON:0013515 subdivision of fallopian tube subdivision of oviduct subdivision of uterine tube uberon uterine tube zone zone of uterine tube subdivision of tube UBERON:0013522 uberon digestive system element Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. UBERON:0013765 digestive organ digestive system organ uberon lateral structure Any structure that is placed on one side of the left-right axis of a bilaterian. This class is primarily to implement taxon constraints. It may be removed in the future. UBERON:0015212 uberon abdominal viscera A viscus that is part of a abdomen. FMA:32413 FMA:67355 UBERON:0017672 abdominal viscera abdominal viscera set set of abdominal viscera uberon bladder organ A membranous sac in animals that serves as the receptacle of a liquid or contains gas. BTO:0000123 UBERON:0018707 bladder uberon reproductive system mucosa BTO:0002439 UBERON:0019042 genital mucosa uberon gray matter of forebrain DHBA:10157 UBERON:0019264 uberon exocrine gland of integumental system An exocrine gland that is part of a integumental system. UBERON:0019319 integumental exocrine gland integumental system exocrine gland uberon lymphomyeloid tissue FMA:79770 UBERON:0034769 uberon cervical carcinoma female gonad Ewings sarcoma A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. There are conspicuous foci of necrosis in association with irregular masses of small, regular, rounded or ovoid cells with very scanty cytoplasm. The tumor occurs usually before the age of 20, about twice as frequently in males as in females. (From Dorland, 27th ed; Stedman, 25th ed) A small round cell tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing's sarcoma/peripheral neuroectodermal tumor. It affects mostly males under age 20, and it can occur in soft tissue or bone. Pain and the presence of a mass are the most common clinical symptoms. A spectrum of malignant tumors, affecting mostly males under age 20, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. These tumors may occur in the soft tissues or the bones. Pain and the presence of a mass are the most common clinical symptoms. DOID:3369 ES Ewing Family of Tumors Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Ewing Tumor Ewing sarcoma Ewing's Family of Tumors Ewing's Family of Tumours Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor Ewing's sarcoma Ewing's sarcoma (morphologic abnormality) Ewing's tumour Ewings Tumor GeneRIF:11313995 GeneRIF:11956622 GeneRIF:11992404 GeneRIF:12054564 GeneRIF:12172985 GeneRIF:12447693 GeneRIF:12527902 GeneRIF:12557222 GeneRIF:12700668 GeneRIF:14528100 GeneRIF:14977835 GeneRIF:15044653 GeneRIF:15077162 GeneRIF:15273724 GeneRIF:15282325 GeneRIF:15310753 GeneRIF:15328192 GeneRIF:15581626 GeneRIF:15748890 GeneRIF:15919668 James Malone MSH:D012512 NCIt:C27291 NCIt:C4817 SNOMEDCT:76909002 Tomasz Adamusiak Tumors of the Ewing's Family URI: http://www.ebi.ac.uk/cellline#Ewing_sarcoma 'bone' BTO:0000140 Bones EV:0100140 FMAID:30317 James Malone MAT:0000299 NCIt:C12366 Osseous Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system. SAEL:10 TAO:0001514 The hard form of connective tissue that constitutes the majority of the skeleton of most vertebrates; it consists of an organic component (the cells and matrix) and an inorganic, or mineral, component; the matrix contains a framework of collagenous fibers and is impregnated with the mineral component, chiefly calcium phosphate (85 per cent) and calcium carbonate (10 per cent), which imparts the quality of rigidity to bone. URI: http://www.ebi.ac.uk/cellline#bone XAO:0000169 osseous tissue breast carcinoma A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. A carcinoma that originates from breast tissue. CA - Carcinoma of breast CANCER, BREAST Cancer of Breast Cancer of the Breast Carcinoma of Breast Carcinoma of breast (disorder) Carcinoma of breast NOS Carcinoma of breast NOS (disorder) Carcinoma of the Breast DOID:3459 GeneRIF:10713110 GeneRIF:11724803 GeneRIF:11759817 GeneRIF:11802810 GeneRIF:11822878 GeneRIF:11839578 GeneRIF:11859072 GeneRIF:11891846 GeneRIF:11909957 GeneRIF:11948115 GeneRIF:11962738 GeneRIF:11986781 GeneRIF:11992405 GeneRIF:11994274 GeneRIF:12015771 GeneRIF:12034875 GeneRIF:12037665 GeneRIF:12105188 GeneRIF:12115372 GeneRIF:12133473 GeneRIF:12174926 GeneRIF:12197229 GeneRIF:12231533 GeneRIF:12452027 GeneRIF:12462387 GeneRIF:12490973 GeneRIF:12496062 GeneRIF:12499259 GeneRIF:12522268 GeneRIF:12529969 GeneRIF:12538354 GeneRIF:12552965 GeneRIF:12566312 GeneRIF:12581744 GeneRIF:12592371 GeneRIF:12637343 GeneRIF:12640109 GeneRIF:12648519 GeneRIF:12650602 GeneRIF:12653579 GeneRIF:12784332 GeneRIF:12878859 GeneRIF:12879463 GeneRIF:14500350 GeneRIF:14519635 GeneRIF:14584041 GeneRIF:14612940 GeneRIF:14638862 GeneRIF:14654792 GeneRIF:14666627 GeneRIF:14687724 GeneRIF:14692019 GeneRIF:14729059 GeneRIF:14871985 GeneRIF:14966279 GeneRIF:14991534 GeneRIF:15034014 GeneRIF:15034868 GeneRIF:15059510 GeneRIF:15059886 GeneRIF:15067342 GeneRIF:15073116 GeneRIF:15102684 GeneRIF:15102687 GeneRIF:15149158 GeneRIF:15156151 GeneRIF:15168344 GeneRIF:15193258 GeneRIF:15241820 GeneRIF:15241822 GeneRIF:15353581 GeneRIF:15374639 GeneRIF:15451571 GeneRIF:15492258 GeneRIF:15550849 GeneRIF:15578430 GeneRIF:15592496 GeneRIF:15671541 GeneRIF:15693887 GeneRIF:15742334 GeneRIF:15743035 GeneRIF:15837735 GeneRIF:15856430 GeneRIF:15856473 GeneRIF:15863392 GeneRIF:15867228 GeneRIF:15882617 GeneRIF:15920544 GeneRIF:15935701 GeneRIF:15944917 GeneRIF:15999367 GeneRIF:16000313 GeneRIF:16007173 GeneRIF:16024059 GeneRIF:16027728 GeneRIF:16049961 GeneRIF:16054892 GeneRIF:16144914 GeneRIF:16273187 GeneRIF:16295419 James Malone Mammary Carcinoma NCIt:C4872 SNOMEDCT:254838004 SNOMEDCT:286898006 URI: http://www.ebi.ac.uk/cellline#breast_carcinoma breast carcinoma cardiovascular system disease A body system disease which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. ASCVD CARDIOVASC DIS CIRCULATORY DISEASE NOS CVD CVD, NOS CVS disease Cardiovascular Diseases Cardiovascular Disorders Cardiovascular disease, NOS Cardiovascular disease, unspecified Cardiovascular disorder Cardiovascular disorder, NOS Cardiovascular system disease Circulatory system disease NOS Circulatory system disease NOS (disorder) DOID:1287 Disease affecting entire cardiovascular system Disease affecting entire cardiovascular system (disorder) Disease of cardiovascular system Disease of cardiovascular system (disorder) Disease of cardiovascular system, NOS Disorder of cardiovascular system Disorder of cardiovascular system (disorder) Disorder of circulatory system Disorder of circulatory system, NOS Disorder of the circulatory system GeneRIF:11744804 GeneRIF:11821707 GeneRIF:11822583 GeneRIF:11912547 GeneRIF:11934214 GeneRIF:11935372 GeneRIF:11985486 GeneRIF:12052142 GeneRIF:12052841 GeneRIF:12056504 GeneRIF:12065317 GeneRIF:12187094 GeneRIF:12195022 GeneRIF:12201209 GeneRIF:12204797 GeneRIF:12365916 GeneRIF:12431476 GeneRIF:12476328 GeneRIF:12606536 GeneRIF:12669427 GeneRIF:12690916 GeneRIF:12743009 GeneRIF:12818409 GeneRIF:12861348 GeneRIF:12867276 GeneRIF:12898464 GeneRIF:12911596 GeneRIF:12943734 GeneRIF:14967720 GeneRIF:14983217 GeneRIF:14998943 GeneRIF:15008790 GeneRIF:15010202 GeneRIF:15116245 GeneRIF:15166781 GeneRIF:15226189 GeneRIF:15240653 GeneRIF:15257013 GeneRIF:15282206 GeneRIF:15302608 GeneRIF:15314690 GeneRIF:15340249 GeneRIF:15342688 GeneRIF:15351863 GeneRIF:15363820 GeneRIF:15375785 GeneRIF:15459608 GeneRIF:15528465 GeneRIF:15531184 GeneRIF:15565175 GeneRIF:15576850 GeneRIF:15591764 GeneRIF:15598684 GeneRIF:15618240 GeneRIF:15619076 GeneRIF:15627719 GeneRIF:15634270 GeneRIF:15648548 GeneRIF:15653176 GeneRIF:15668644 GeneRIF:15683719 GeneRIF:15735209 GeneRIF:15750260 GeneRIF:15780075 GeneRIF:15780820 GeneRIF:15823283 GeneRIF:15855354 GeneRIF:15856070 GeneRIF:15859024 GeneRIF:15869613 GeneRIF:15939053 GeneRIF:16018179 GeneRIF:16028070 GeneRIF:16046727 GeneRIF:16102632 GeneRIF:16103519 GeneRIF:16109314 GeneRIF:16132053 GeneRIF:16159596 GeneRIF:16159602 GeneRIF:16161810 GeneRIF:16224057 GeneRIF:16260427 GeneRIF:16324215 ICD9:390-459.99 ICD9:420-429.99 ICD9:423 ICD9:423.8 ICD9:424 ICD9:429 ICD9:429.2 ICD9:429.7 ICD9:429.79 ICD9:429.8 ICD9:429.81 ICD9:429.89 ICD9:459.9 ILL-DEFINED HRT DIS NEC James Malone MSH:D002318 NCIt:C2931 OTHER SEQUELAE OF MI NEC Other diseases of endocardium Other diseases of endocardium (disorder) Other diseases of pericardium Other diseases of pericardium (disorder) Other disorders of papillary muscle Other forms of heart disease Other forms of heart disease (disorder) Other heart disease Other heart disease (disorder) Other heart disease NOS Other heart disease NOS (disorder) Other ill-defined heart disease Other ill-defined heart disease (disorder) Other ill-defined heart disease NOS Other ill-defined heart disease NOS (disorder) Other ill-defined heart diseases Other pericardial disease NOS Other pericardial disease NOS (disorder) Other sequelae of myocardial infarction, not elsewhere classified Other specified diseases of pericardium Other specified pericardial disease NOS Other specified pericardial disease NOS (disorder) PAPILLARY MUSCLE DIS NEC PERICARDIAL DISEASE NEC Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. SNOMEDCT:105980002 SNOMEDCT:194901009 SNOMEDCT:194962004 SNOMEDCT:195150009 SNOMEDCT:195151008 SNOMEDCT:195551001 SNOMEDCT:195553003 SNOMEDCT:195588003 SNOMEDCT:195594006 SNOMEDCT:195646003 SNOMEDCT:266239001 SNOMEDCT:266240004 SNOMEDCT:266241000 SNOMEDCT:266251004 SNOMEDCT:266309008 SNOMEDCT:49601007 URI: http://www.ebi.ac.uk/cellline#cardiovascular_disease Unspecified circulatory system disorder [X]Cardiovascular disease, unspecified [X]Cardiovascular disease, unspecified (disorder) [X]Other forms of heart disease [X]Other forms of heart disease (disorder) [X]Other ill-defined heart diseases [X]Other ill-defined heart diseases (disorder) [X]Other specified diseases of pericardium [X]Other specified diseases of pericardium (disorder) cardiovascular disease circulatory system disease disease of subdivision of hemolymphoid system disease A disease is a disposition that describes states of disease associated with a particular sample and/or organism. James Malone reproductive system disease DOID:15 Disorder of reproductive system Disorder of reproductive system (disorder) James Malone Non-neoplastic Reproductive system disease SNOMEDCT:362968007 Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#reproductive_system_disease genital system disease reproductive system disease germ cell cancer A cancer that is derived from germ cells. Cancer, Embryonal Cancer, Embryonal and Mixed DOID:2994 EMBRYONAL NEOPL Embryonal Cancers Embryonal Neoplasms GERM CELL EMBRYONAL NEOPL GeneRIF:12163388 GeneRIF:12620992 GeneRIF:12629412 GeneRIF:12727846 GeneRIF:12736724 GeneRIF:12777997 GeneRIF:12824871 GeneRIF:14555521 GeneRIF:14633588 GeneRIF:15330164 GeneRIF:15467433 GeneRIF:15491742 GeneRIF:15691383 GeneRIF:15896468 GeneRIF:15982323 GeneRIF:16188233 Germ Cell Cancers Germ Cell Tumors Germ Cell and Embryonal Neoplasms Germ Cell and Embryonic Neoplasms Germ cell neoplasm Germ cell neoplasm (morphologic abnormality) Germ cell neoplasm NOS (morphologic abnormality) Germ cell neoplasms (morphologic abnormality) Germ cell tumor, NOS Germinoma Germinoma (morphologic abnormality) James Malone MSH:D009373 NCIt:C3708 NEOPL GERM CELL NEOPL GERM CELL EMBRYONIC Neoplasm of Germ Cell Neoplasm of the Germ Cell Neoplasm, Embryonal Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS. Neoplasms, Embryonal and Mixed Neoplasms, Germ Cell SNOMEDCT:115233005 SNOMEDCT:189839002 SNOMEDCT:189854008 SNOMEDCT:28307001 SNOMEDCT:402878003 Tumor of Germ Cell Tumor of the Germ Cell URI: http://www.ebi.ac.uk/cellline#germ_cell_tumor [M]Germ cell neoplasm NOS [M]Germ cell neoplasm NOS (morphologic abnormality) [M]Germ cell neoplasms [M]Germ cell neoplasms (morphologic abnormality) germ cell cancer germ cell tumor germ cell tumor (disorder) germ cell tumour malignant tumor of the germ cell glioma A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas. Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) DOID:2627 GeneRIF:11705870 GeneRIF:11716065 GeneRIF:11716067 GeneRIF:11716069 GeneRIF:11809417 GeneRIF:11836615 GeneRIF:11844831 GeneRIF:11856869 GeneRIF:11859970 GeneRIF:11913980 GeneRIF:11920587 GeneRIF:11930164 GeneRIF:11948808 GeneRIF:11949822 GeneRIF:12061725 GeneRIF:12084351 GeneRIF:12118245 GeneRIF:12125964 GeneRIF:12130632 GeneRIF:12133571 GeneRIF:12198774 GeneRIF:12231538 GeneRIF:12388547 GeneRIF:12388552 GeneRIF:12496285 GeneRIF:12507885 GeneRIF:12507886 GeneRIF:12509854 GeneRIF:12518988 GeneRIF:12545160 GeneRIF:12576462 GeneRIF:12600989 GeneRIF:12609716 GeneRIF:12629150 GeneRIF:12651623 GeneRIF:12651906 GeneRIF:12684632 GeneRIF:12698196 GeneRIF:12730958 GeneRIF:12735302 GeneRIF:12738994 GeneRIF:12764090 GeneRIF:12778072 GeneRIF:12783249 GeneRIF:12799382 GeneRIF:12810672 GeneRIF:12821932 GeneRIF:12843258 GeneRIF:12843260 GeneRIF:12850541 GeneRIF:12856717 GeneRIF:12881718 GeneRIF:12883693 GeneRIF:12907597 GeneRIF:12932816 GeneRIF:12957651 GeneRIF:12962281 GeneRIF:12963026 GeneRIF:13130092 GeneRIF:13130506 GeneRIF:14504888 GeneRIF:14530312 GeneRIF:14558597 GeneRIF:14597411 GeneRIF:14603470 GeneRIF:14633698 GeneRIF:14676120 GeneRIF:14705150 GeneRIF:14719118 GeneRIF:14991747 GeneRIF:14997014 GeneRIF:15015771 GeneRIF:15015772 GeneRIF:15041728 GeneRIF:15047712 GeneRIF:15056287 GeneRIF:15072448 GeneRIF:15088070 GeneRIF:15094455 GeneRIF:15123617 GeneRIF:15126357 GeneRIF:15138575 GeneRIF:15160992 GeneRIF:15161654 GeneRIF:15178645 GeneRIF:15184909 GeneRIF:15193433 GeneRIF:15198128 GeneRIF:15201971 GeneRIF:15201989 GeneRIF:15218947 GeneRIF:15254085 GeneRIF:15256062 GeneRIF:15269346 GeneRIF:15273738 GeneRIF:15332324 GeneRIF:15334059 GeneRIF:15361550 GeneRIF:15383564 GeneRIF:15451022 GeneRIF:15469737 GeneRIF:15469871 GeneRIF:15469933 GeneRIF:15509526 GeneRIF:15527101 GeneRIF:15531913 GeneRIF:15547763 GeneRIF:15557754 GeneRIF:15580288 GeneRIF:15580296 GeneRIF:15589840 GeneRIF:15592495 GeneRIF:15657358 GeneRIF:15671555 GeneRIF:15684595 GeneRIF:15696967 GeneRIF:15696973 GeneRIF:15737330 GeneRIF:15743799 GeneRIF:15774464 GeneRIF:15788675 GeneRIF:15791479 GeneRIF:15809742 GeneRIF:15812817 GeneRIF:15814461 GeneRIF:15816541 GeneRIF:15867349 GeneRIF:15867356 GeneRIF:15870690 GeneRIF:15882793 GeneRIF:15893739 GeneRIF:15915502 GeneRIF:15948146 GeneRIF:15958622 GeneRIF:15973152 GeneRIF:15989758 GeneRIF:16027728 GeneRIF:16033774 GeneRIF:16033775 GeneRIF:16049340 GeneRIF:16084492 GeneRIF:16092940 GeneRIF:16098466 GeneRIF:16215635 GeneRIF:16264179 GeneRIF:16304992 GeneRIF:16389900 GeneRIF:9109541 Glial Cell Tumor Glial Neoplasm Glial Tumor Glioma Glioma (except Nasal glioma, not neoplastic) Glioma NOS Glioma NOS (morphologic abnormality) Glioma, Mixed Glioma, NOS (except Nasal glioma, not neoplastic) Glioma, malignant (morphologic abnormality) Glioma, malignant, no ICD-O subtype Gliomas Gliomas (morphologic abnormality) Gliomas, Malignant Gliomas, Mixed James Malone MSH:D005910 Malignant glioma NCIt:C3059 Neoplasm of Neuroglia Neoplasm of the Neuroglia Neoplasms of Neuroglia Neuroglial Neoplasm Neuroglial Neoplasms Neuroglial Tumor Replaced with central nervous system cancer (EFO_0000326) SNOMEDCT:115240006 SNOMEDCT:189908003 SNOMEDCT:189926000 SNOMEDCT:74532006 Tumor of Neuroglia Tumor of the Neuroglia Tumors of Neuroglia Tumors, Glial Cell URI: http://www.ebi.ac.uk/cellline#obsolete_glioma [M]Glioma NOS [M]Glioma NOS (morphologic abnormality) [M]Gliomas [M]Gliomas (morphologic abnormality) glial tumors glioma (morphologic abnormality) obsolete_glioma immune system disease AUTOIMMUNE DISEASE NEC Autoimmune disease, not elsewhere classified DEFIC CELL IMMUNITY NOS DOID:2914 Disorder of the immune mechanism NOS Disorder of the immune mechanism NOS (disorder) ICD9:279 ICD9:279.1 ICD9:279.10 ICD9:279.19 ICD9:279.4 ICD9:279.8 ICD9:279.9 IMMUNDEF T-CELL DEF NOS IMMUNE MECHANISM DIS NEC IMMUNE MECHANISM DIS NOS Immune System and Related Disorders Immunodeficiency and Immunosuppression Disorders Immunodeficiency with predominant T-cell defect, unspecified James Malone NCIt:C27351 Other deficiency of cell-mediated immunity Other specified disorders involving the immune mechanism Other specified disorders of the immune mechanism Other specified disorders of the immune mechanism (disorder) SNOMEDCT:191017001 SNOMEDCT:191019003 SNOMEDCT:191035005 URI: http://www.ebi.ac.uk/cellline#immune_system_disease Unspecified disorder of immune mechanism [X]Disorder involving the immune mechanism, unspecified [X]Disorder involving the immune mechanism, unspecified (disorder) immune system disease lymphoma A cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs. A general term for various neoplastic diseases of the lymphoid tissue. A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas. DOID:353 GeneRIF:11720250 GeneRIF:11751994 GeneRIF:11836626 GeneRIF:11866986 GeneRIF:11869933 GeneRIF:11920179 GeneRIF:11932403 GeneRIF:11937265 GeneRIF:11985791 GeneRIF:11999550 GeneRIF:12048235 GeneRIF:12082638 GeneRIF:12145697 GeneRIF:12149433 GeneRIF:12208847 GeneRIF:12217802 GeneRIF:12218099 GeneRIF:12351407 GeneRIF:12393693 GeneRIF:12438221 GeneRIF:12469325 GeneRIF:12496417 GeneRIF:12532332 GeneRIF:12532453 GeneRIF:12539045 GeneRIF:12549480 GeneRIF:12555065 GeneRIF:12567186 GeneRIF:12569164 GeneRIF:12579309 GeneRIF:12604405 GeneRIF:12682649 GeneRIF:12688322 GeneRIF:12721791 GeneRIF:12807718 GeneRIF:12884297 GeneRIF:12897143 GeneRIF:12915884 GeneRIF:12967477 GeneRIF:14612522 GeneRIF:14654791 GeneRIF:14662861 GeneRIF:14666612 GeneRIF:14691303 GeneRIF:14702288 GeneRIF:14724650 GeneRIF:14767575 GeneRIF:14998493 GeneRIF:15121848 GeneRIF:15126346 GeneRIF:15133473 GeneRIF:15160902 GeneRIF:15215324 GeneRIF:15223017 GeneRIF:15226424 GeneRIF:15263076 GeneRIF:15265020 GeneRIF:15325703 GeneRIF:15356104 GeneRIF:15467748 GeneRIF:15474489 GeneRIF:15516976 GeneRIF:15522957 GeneRIF:15551285 GeneRIF:15562971 GeneRIF:15569983 GeneRIF:15640350 GeneRIF:15649253 GeneRIF:15668399 GeneRIF:15677569 GeneRIF:15692060 GeneRIF:15705798 GeneRIF:15713979 GeneRIF:15716988 GeneRIF:15735694 GeneRIF:15743832 GeneRIF:15744340 GeneRIF:15762053 GeneRIF:15889157 GeneRIF:15890690 GeneRIF:15902285 GeneRIF:15940251 GeneRIF:15985538 GeneRIF:16108830 GeneRIF:16194892 GeneRIF:16201318 GeneRIF:16277027 Germinoblastic Sarcomas Germinoblastoma Germinoblastomas James Malone Lymphoma (Hodgkin's and Non-Hodgkin's) Lymphoma (Non-Hodgkin) Lymphoma (clinical) Lymphoma, NOS Lymphomas Lymphomas, Malignant MSH:D008223 Malignant lymphoma Malignant lymphoma (clinical) Malignant lymphoma NOS of unspecified site Malignant lymphoma NOS of unspecified site (disorder) Malignant lymphoma, NOS Malignant lymphoma, no ICD-O subtype Microglioma [obs] NCIt:C3208 Reticulolymphosarcoma Reticulolymphosarcoma NOS Reticulolymphosarcomas SNOMEDCT:118600007 SNOMEDCT:188694002 SNOMEDCT:188695001 SNOMEDCT:21964009 Sarcoma, Germinoblastic This is potentially too broad as well as overlaps with leukemia and should be obsoleted. URI: http://www.ebi.ac.uk/cellline#lymphoma lymphoma malignant lymphoma (disorder) malignant lymphoma NOS (disorder) malignant lymphoma, no ICD-O subtype (morphologic abnormality) disease of metabolism A congenital (due to inherited enzyme abnormality) or acquired (due to failure of a metabolic important organ) disorder resulting from an abnormal metabolic process. -- 2003 DOID:0014667 GeneRIF:12093894 GeneRIF:12215968 GeneRIF:12242462 GeneRIF:12707035 GeneRIF:12815182 GeneRIF:12824951 GeneRIF:14592951 GeneRIF:15231871 GeneRIF:15246202 GeneRIF:15277400 GeneRIF:15677734 GeneRIF:16018179 Generalised metabolic disorder Generalized metabolic disorder Generalized metabolic disorder (disorder) Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed) ICD9:277.9 James Malone MD - Metabolic disorders METAB DIS METABOLISM DISORDER NOS MSH:D008659 Metabolic Diseases Metabolic disease (disorder) Metabolic disease, NOS Metabolic disorder Metabolic disorder, NOS Metabolic disorders NCIt:C3235 SNOMEDCT:267456000 SNOMEDCT:30390004 SNOMEDCT:75934005 Thesaurismoses Thesaurismosis URI: http://www.ebi.ac.uk/cellline#metabolic_disease Unspecified disorder of metabolism disease of metabolism disorder of metabolism NOS disorder of metabolism NOS (disorder) metabolic disease metabolism disorder neuroblastoma (Neuroblastoma NOS) or (sympathicoblastoma) A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH). A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation. Central neuroblastoma DOID:769 GeneRIF:11705866 GeneRIF:11737230 GeneRIF:11744098 GeneRIF:11782392 GeneRIF:11807986 GeneRIF:11836564 GeneRIF:11859407 GeneRIF:11861392 GeneRIF:11870543 GeneRIF:11877670 GeneRIF:11877677 GeneRIF:11881792 GeneRIF:11928813 GeneRIF:12031683 GeneRIF:12085233 GeneRIF:12118090 GeneRIF:12154078 GeneRIF:12163469 GeneRIF:12174591 GeneRIF:12185581 GeneRIF:12209604 GeneRIF:12239177 GeneRIF:12438307 GeneRIF:12545167 GeneRIF:12557224 GeneRIF:12576454 GeneRIF:12593854 GeneRIF:12598334 GeneRIF:12629151 GeneRIF:12629521 GeneRIF:12647219 GeneRIF:12672031 GeneRIF:12675130 GeneRIF:12717420 GeneRIF:12808116 GeneRIF:12829373 GeneRIF:12884264 GeneRIF:12888911 GeneRIF:12907629 GeneRIF:12916719 GeneRIF:12962147 GeneRIF:12964007 GeneRIF:13679866 GeneRIF:14645238 GeneRIF:14654552 GeneRIF:14663483 GeneRIF:14719101 GeneRIF:14724587 GeneRIF:14745549 GeneRIF:14988008 GeneRIF:14995074 GeneRIF:15004408 GeneRIF:15015775 GeneRIF:15024693 GeneRIF:15083193 GeneRIF:15117961 GeneRIF:15136145 GeneRIF:15166121 GeneRIF:15168079 GeneRIF:15218241 GeneRIF:15240516 GeneRIF:15280446 GeneRIF:15316056 GeneRIF:15322424 GeneRIF:15328517 GeneRIF:15375504 GeneRIF:15448191 GeneRIF:15486895 GeneRIF:15488758 GeneRIF:15514946 GeneRIF:15516980 GeneRIF:15518890 GeneRIF:15547663 GeneRIF:15607966 GeneRIF:15618969 GeneRIF:15644444 GeneRIF:15650242 GeneRIF:15719172 GeneRIF:15735700 GeneRIF:15741235 GeneRIF:15827327 GeneRIF:15849504 GeneRIF:15882878 GeneRIF:15930276 GeneRIF:15994346 GeneRIF:15998644 GeneRIF:16007146 GeneRIF:16051641 GeneRIF:16091745 GeneRIF:16092940 GeneRIF:16098972 GeneRIF:16125842 GeneRIF:16166307 GeneRIF:16177824 GeneRIF:16228012 GeneRIF:16232196 James Malone MSH:D009447 NB - Neuroblastoma NCIt:C3270 NIFSTD:birnlex_12631 Neuroblastoma (Schwannian Stroma-Poor) Neuroblastoma, NOS Neuroblastomas SNOMEDCT:269507008 SNOMEDCT:87364003 Sympathicoblastoma Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#neuroblastoma [M]Neuroblastoma NOS [M]Neuroblastoma NOS (morphologic abnormality) neuroblastoma neuroblastoma (morphologic abnormality) neuroblastoma NOS (morphologic abnormality) organism part James Malone Jie Zheng MO_954 The part of organism's anatomy or substance arising from an organism from which the biomaterial was derived, excludes cells. E.g. tissue, organ, system, sperm, blood or body location (arm). Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#organism_part tissue, organ, system, sperm, blood or body location (arm). osteosarcoma A malignant mesenchymal tumor arising from the bone. A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) A usually aggressive malignant bone-forming mesenchymal tumor, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs. Bone Sarcoma DOID:3347 GeneRIF:11606061 GeneRIF:11746983 GeneRIF:11776394 GeneRIF:11920494 GeneRIF:11927012 GeneRIF:11943335 GeneRIF:12009018 GeneRIF:12054567 GeneRIF:12154052 GeneRIF:12209731 GeneRIF:12237108 GeneRIF:12376862 GeneRIF:12393937 GeneRIF:12479099 GeneRIF:12544770 GeneRIF:12660817 GeneRIF:12663494 GeneRIF:12709413 GeneRIF:12788094 GeneRIF:12792742 GeneRIF:12972634 GeneRIF:13678785 GeneRIF:14524531 GeneRIF:14528100 GeneRIF:14584080 GeneRIF:14598886 GeneRIF:14645574 GeneRIF:14679136 GeneRIF:14704791 GeneRIF:14710359 GeneRIF:14719070 GeneRIF:15026342 GeneRIF:15087387 GeneRIF:15145525 GeneRIF:15201972 GeneRIF:15210853 GeneRIF:15221963 GeneRIF:15310147 GeneRIF:15448009 GeneRIF:15469899 GeneRIF:15476586 GeneRIF:15488761 GeneRIF:15580288 GeneRIF:15583032 GeneRIF:15609301 GeneRIF:15662138 GeneRIF:15668906 GeneRIF:15701832 GeneRIF:15719069 GeneRIF:15796961 GeneRIF:15814634 GeneRIF:15870699 GeneRIF:15900593 GeneRIF:15922739 GeneRIF:16010425 GeneRIF:16035619 GeneRIF:16087680 GeneRIF:16157226 GeneRIF:16328004 James Malone MSH:D012516 NCIt:C9145 NCIt:C9312 Osseous Sarcoma Osteoblastic osteosarcoma Osteoblastic sarcoma Osteochondrosarcoma Osteogenic Sarcomas Osteogenic sarcoma, NOS Osteosarcoma - disorder Osteosarcoma of bone Osteosarcoma of bone (disorder) Osteosarcoma, NOS Osteosarcoma, no ICD-O subtype Osteosarcoma, no ICD-O subtype (morphologic abnormality) Osteosarcomas SNOMEDCT:21708004 SNOMEDCT:307576001 Sarcoma of Bone Sarcoma of the Bone Sarcoma, Osteogenic Skeletal sarcoma URI: http://www.ebi.ac.uk/cellline#osteosarcoma [M]Osteosarcoma NOS osteoid sarcoma osteosarcoma sarcoma A cancer that affects connective tissue resulting in mesoderm proliferation. A malignant mesenchymal neoplasm arising exclusively from the soft tissues. Representative examples include soft tissue sarcoma, extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor, and malignant hemangiopericytoma. A malignant mesenchymal neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones. Connective Tissue Sarcoma DOID:1115 GeneRIF:11953898 GeneRIF:12112526 GeneRIF:12435619 GeneRIF:12539045 GeneRIF:12610779 GeneRIF:14507652 GeneRIF:14612455 GeneRIF:14710346 GeneRIF:15018431 GeneRIF:15201968 GeneRIF:15710230 GeneRIF:15716602 GeneRIF:15809709 GeneRIF:16154137 GeneRIF:16327442 ICD9:171 ICD9:171.0 ICD9:171.2 ICD9:171.3 ICD9:171.4 ICD9:171.5 ICD9:171.6 ICD9:171.7 ICD9:171.8 ICD9:171.9 James Malone MAL NEO SOFT TIS ABDOMEN MAL NEO SOFT TIS PELVIS MAL NEO SOFT TIS THORAX MAL NEO SOFT TISSUE ARM MAL NEO SOFT TISSUE HEAD MAL NEO SOFT TISSUE LEG MAL NEO SOFT TISSUE NEC MAL NEO SOFT TISSUE NOS MAL NEOPL TRUNK NOS Malignant Neoplasm of the Soft Tissue Malignant Soft Tissue Neoplasm Malignant Soft Tissue Tumor Malignant Tumor of the Soft Tissue Malignant mesenchymal tumour Malignant neoplasm of connective and other soft tissue Malignant neoplasm of connective and other soft tissue (disorder) Malignant neoplasm of connective and other soft tissue of abdomen Malignant neoplasm of connective and other soft tissue of head, face, and neck Malignant neoplasm of connective and other soft tissue of lower limb, including hip Malignant neoplasm of connective and other soft tissue of pelvis Malignant neoplasm of connective and other soft tissue of thorax Malignant neoplasm of connective and other soft tissue of trunk, unspecified Malignant neoplasm of connective and other soft tissue of upper limb, including shoulder Malignant neoplasm of connective and other soft tissue, site unspecified Malignant neoplasm of other specified sites of connective and other soft tissue Malignant neoplasm of soft tissue Malignant neoplasm of soft tissue (disorder) Malignant tumor of soft tissue Malignant tumour of soft tissue Mesenchymal tumor, malignant NCIt:C4867 NCIt:C9118 NCIt:C9306 SNOMEDCT:187985009 SNOMEDCT:189764008 SNOMEDCT:2424003 SNOMEDCT:269469005 Sarcoma of Soft Tissue Sarcoma of Soft Tissue and Bone Sarcoma of the Soft Tissue Sarcoma of the Soft Tissue and Bone Sarcoma, NOS Sarcoma, no ICD-O subtype Sarcoma, no ICD-O subtype (morphologic abnormality) Soft Tissue Sarcoma Soft tissue tumour, malignant Type of cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. URI: http://www.ebi.ac.uk/cellline#sarcoma [M]Sarcoma NOS [M]Sarcoma NOS (morphologic abnormality) connective and soft tissue neoplasm sarcoma tumor of soft tissue and skeleton cardiovascular system BTO:0000088 CV system EHDAA:394 EMAPA:16104 EV:0100017 FBbt:00005057 FMAID:7161 James Malone MA:0000010 MAT:0000016 MFO:000290 Organ system which consists of the heart, the systemic and pulmonary arterial and venous system, the lymphatic and the portal venous system. SAEL:16 TADS:0000146 TAO:0000010 The system of heart and blood vessels. URI: http://www.ebi.ac.uk/cellline#cardiovascular_system XAO:0000100 ZFA:0000010 circulatory system digestive system component AAO:0000129 EHDAA:514 EMAPA:16246 EV:0100056 FBbt:00005055 FMAID:7152 James Malone MA:0000323 MAT:0000018 MFO:0002980 SAEL:28 TADS:0000170 TAO:0000339 The organ system involved in the absorption of nutrients. URI: http://www.ebi.ac.uk/cellline#digestive_system_component WBbt:0005748 XAO:0000125 ZFA:0000339 alimentary system digestive system gastrointestinal system gland A cell, group of cells, or organ of endothelial origin that selectively removes materials from the blood, concentrates or alters them, and secretes them for further use in the body or for elimination from the body. BTO:0000522 FBbt:00003214 James Malone MA:0002563 MA:0002564 SAEL:33 SAEL:37 TAO:0001158 URI: http://www.ebi.ac.uk/cellline#gland XAO:0000158 haemopoietic system James Malone MA:0002434 MAT:0000022 SAEL:48 URI: http://www.ebi.ac.uk/cellline#haemopoietic_system XAO:0000122 hematological system hematolymphoid system muscular system AAO:0000307 BTO:0001485 EV:0100146 FBbt:00005069 James Malone MA:0000015 MAT:0000025 MFO:0002100 TADS:0000324 TAO:0000548 The bodily system that is composed of skeletal, smooth, and cardiac muscle tissue and functions in movement of the body or of materials through the body, maintenance of posture, and heat production. URI: http://www.ebi.ac.uk/cellline#muscular_system WBbt:0005737 ZFA:0000548 motor system muscle muscle system muscles musculature musculature system muscule system nervous system A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com) AAO:0000324 All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems. BTO:0001484 EHDAA:826 EMAPA:16469 EV:0100162 FBbt:00005093 FMAID:7157 James Malone MA:0000016 MAT:0000026 NIFSTD:birnlex_844 SAEL:71 TAO:0000396 The nervous system is essentially a biological information highway, and is responsible for controlling all the biological processes and movement in the body, and can also receive information and interpret it via electrical signals which are used in this nervous system. It consists of the Central Nervous System (CNS), essentially the processing area and the Peripheral Nervous System which detects and sends electrical impulses that are used in the nervous system. Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#nervous_system WBbt:0005735 XAO:0000177 ZFA:0000396 respiratory system structure . A system of organs subserving the function of respiration and in air-breathing vertebrates consisting typically of the lungs and their nervous and circulatory supply and the channels by which these are continuous with the outer air. AAO:0000541 Apparatus respiratorius BTO:0000203 EHDAA:2203 EMAPA:16727 EV:0100036 FBbt:00005024 FMAID:7158 Functional system which consists of structures involved in respiration. James Malone MA:0000327 MAT:0000030 MFO:0003160 SAEL:90 TADS:0000043 TAO:0000272 URI: http://www.ebi.ac.uk/cellline#respiratory_system_structure XAO:0000117 respiratory system respiratory tract tracheal system skeleton structure EHDAA:5047 EMAPA:17213 FMAID:23875 James Malone MA:0000018 MAT:0000032 Set of all bones Set of bones in the entire body. Set of bones of body Skeleton TAO:0000434 URI: http://www.ebi.ac.uk/cellline#skeleton_structure ZFA:0000434 skeletal system skeleton component integumental system A division of the whole organism into specialized systems. AAO:0000239 BTO:0000634 EHDAA:6520 EMAPA:17524 EV:0100151 FBbt:00004856 FMAID:72979 Integumentary system James Malone MA:0000014 MAT:0000033 Something that covers or encloses; especially: an enveloping layer (as a skin, membrane, or husk) of an organism or one of its parts. TADS:0000108 The taxon-independent term for the outer covering of an organism URI: http://www.ebi.ac.uk/cellline#integumental_system WBbt:0005730 XAO:0000176 dermal system epithelial system - sensu C elegans integument tegument animal reproductive system EHDAA:5923 EMAPA:17381 EV:0100100 FBbt:00004857 FMAID:7160 James Malone MAT:0000305 Reproductive system SAEL:89 TAO:0000632 URI: http://www.ebi.ac.uk/cellline#animal_reproductive_system XAO:0000142 genital system reproductive system - animals intestine AAO:0000246 BTO:0000648 Bowel EHDAA:518 EV:0100071 FMAID:7199 James Malone MA:0000328 MAT:0000043 MFO:0003040 SAEL:55 TADS:0000165 TAO:0001338 TGMA:0001819 The fluid-feeding habit of adult mosquitoes is reflected in the structure and ultrastructure of the alimentary canal. The tubular part of the alimentary canal that extends from the stomach to the anus. URI: http://www.ebi.ac.uk/cellline#intestine WBbt:0005772 XAO:0000129 ZFA:0001338 adult alimentary canal gut intestines mammary gland BTO:0000817 EHDAA:6522 EMAPA:17759 EV:0100125 FMAID:62088 James Malone Lactiferous gland Lobe of breast Lobe of mammary gland Lobular organ which consist of a lactiferous duct tree and the set of lactiferous acini that are connected to duct tree. Examples: There are variable numbers of lactiferous duct trees. MA:0000145 MAT:0000073 SAEL:64 The specialized accessory gland of the skin of female mammals that secretes milk. In the human female, it is a compound tubuloalveolar gland composed of 15 to 25 lobes arranged radially about the nipple and separated by connective and adipose tissue, each lobe having its own excretory (lactiferous) duct opening on the nipple. The lobes are subdivided into lobules, with the alveolar ducts and alveoli being the secretory portion of the gland. URI: http://www.ebi.ac.uk/cellline#mammary_gland glandula mammaria mamma lymphatic system EHDAA:8677 EMAPA:18248 FMAID:5034 James Malone MA:0000139 SAEL:63 URI: http://www.ebi.ac.uk/cellline#lymphatic_system peripheral nervous system AAO:0000429 BTO:0001028 EHDAA:2893 EMAPA:16665 FBbt:00005098 James Malone MAT:0000338 PNS TADS:0000221 The outer parts of the nervous system that perform sensory and motor functions. The peripheral nervous system (PNS) connects the central nervous system (CNS) to sensory organs (such as the eye and ear), other organs of the body, muscles, blood vessels and glands. URI: http://www.ebi.ac.uk/cellline#peripheral_nervous_system XAO:0000178 sympathetic nervous system BTO:0001832 EHDAA:3769 EMAPA:16985 EV:0100374 FMAID:9906 James Malone MA:0000225 MAT:0000100 Nervous structures including ganglia outside of the central nervous system. One of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord, and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera, and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. PNS - sympathetic Sympathetic part of autonomic division of nervous system TAO:0001576 URI: http://www.ebi.ac.uk/cellline#sympathetic_nervous_system XAO:0000211 ZFA:0000142 peripheral nervous system pns sympathetic chain lung AAO:0000275 BTO:0000763 EHDAA:2205 EMAPA:16728 EV:0100042 FMAID:7195 James Malone Lobular organ which has as its parts alveoli connected to the tracheobronchial tree. Examples: There are only two instances, right lung and left lung. MA:0000415 MAT:0000135 One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates. SAEL:62 URI: http://www.ebi.ac.uk/cellline#lung XAO:0000119 lungs connective tissue BTO:0000421 EV:0100150 FMAID:9640 James Malone MAT:0000301 Portion of connective tissue SAEL:23 TAO:0009189 The tissue which binds together and is the support of the various structures of the body. It is made up of fibroblasts, fibroglia, collagen fibrils, and elastic fibrils. It is derived from the mesoderm and in a broad sense includes the collagenous, elastic, mucous, reticular, osseous, and cartilaginous tissue. Some also include the blood in this group of tissues. Connective tissue is classified according to concentration of fibers as loose (areolar) and dense, the latter having more abundant fibers than the former. Tissue which consists of fibroblasts, osteocytes or chondrocytes and intercellular matrix produced by these cells. Examples: bone (tissue), dense regular elastic tissue, areolar tissue, neuroglia, adipose tissue. URI: http://www.ebi.ac.uk/cellline#connective_tissue XAO:0000173 fascia muscle attachment cell tendon tendon cell skin BTO:0001253 EHDAA:6530 EMAPA:17525 EV:0100152 FMAID:7163 James Malone MAT:0000284 MFO:0003200 Nonparenchymatous organ that consists of the epidermis, dermis and sets of hair and nails and which surrounds the entire body. Subdivisions of the skin surround various body parts; as a whole, the skin constitutes the external layer of the body. Examples: There is only one skin. SAEL:95 Skin of body The integument of an animal (as a fur-bearing mammal or a bird) separated from the body usually with its hair or feathers. URI: http://www.ebi.ac.uk/cellline#skin XAO:0000023 female reproductive system . BTO:0000083 EHDAA:8116 EMAPA:17959 EV:0100110 FBbt:00004864 FMAID:45663 Gonochoristic organism that can produce female gametes. James Malone MA:0000381 TADS:0000352 The reproductive system in women includes the ovaries, the fallopian tubes, the uterus (womb), the cervix, and the vagina (birth canal). URI: http://www.ebi.ac.uk/cellline#female_reproductive_system XAO:0000156 ZFA:0000303 gynaecological tissue animal ovary AAO:0000371 EHDAA:8124 EMAPA:17962 EV:0100111 FBbt:00004865 FMAID:7209 Female reproductive organ. James Malone MA:0000384 MAT:0000125 SAEL:76 TADS:0000400 TAO:0000403 URI: http://www.ebi.ac.uk/cellline#animal_ovary XAO:0000258 ZFA:0000403 ovaries ovary cervix A constricted portion of an organ or part; especially: the narrow outer end of the uterus. BTO:0001421 Cervical canal Cervical canal of uterus Cervix of uterus EV:0100114 FMAID:17740 James Malone MAT:0000292 Neck of uterus SAEL:118 URI: http://www.ebi.ac.uk/cellline#cervix Uterine cervix multiple myeloma DOID:9538 GeneRIF:11568006 GeneRIF:11745168 GeneRIF:11792572 GeneRIF:11830480 GeneRIF:11830493 GeneRIF:11830495 GeneRIF:11839670 GeneRIF:11840273 GeneRIF:11872084 GeneRIF:11877256 GeneRIF:11877293 GeneRIF:11877294 GeneRIF:11877296 GeneRIF:11896542 GeneRIF:11902142 GeneRIF:11918087 GeneRIF:11940485 GeneRIF:11985783 GeneRIF:12001122 GeneRIF:12002771 GeneRIF:12070027 GeneRIF:12070032 GeneRIF:12161360 GeneRIF:12199782 GeneRIF:12200385 GeneRIF:12200397 GeneRIF:12231535 GeneRIF:12239172 GeneRIF:12351414 GeneRIF:12368157 GeneRIF:12377412 GeneRIF:12393489 GeneRIF:12393542 GeneRIF:12430875 GeneRIF:12433678 GeneRIF:12433679 GeneRIF:12456503 GeneRIF:12459170 GeneRIF:12471202 GeneRIF:12517814 GeneRIF:12543106 GeneRIF:12560229 GeneRIF:12569357 GeneRIF:12574959 GeneRIF:12576455 GeneRIF:12604407 GeneRIF:12626569 GeneRIF:12649140 GeneRIF:12651942 GeneRIF:12660820 GeneRIF:12665525 GeneRIF:12682635 GeneRIF:12707028 GeneRIF:12743296 GeneRIF:12791655 GeneRIF:12845688 GeneRIF:12855565 GeneRIF:12888915 GeneRIF:12931219 GeneRIF:12969979 GeneRIF:12970749 GeneRIF:14512299 GeneRIF:14513045 GeneRIF:14513053 GeneRIF:14514474 GeneRIF:14592826 GeneRIF:14656874 GeneRIF:14671622 GeneRIF:14677065 GeneRIF:14692531 GeneRIF:14715624 GeneRIF:14755377 GeneRIF:14976049 GeneRIF:15000866 GeneRIF:15003892 GeneRIF:15010462 GeneRIF:15041705 GeneRIF:15061198 GeneRIF:15070695 GeneRIF:15070697 GeneRIF:15070700 GeneRIF:15138161 GeneRIF:15172968 GeneRIF:15199411 GeneRIF:15203873 GeneRIF:15205949 GeneRIF:15215163 GeneRIF:15458509 GeneRIF:15471949 GeneRIF:15475450 GeneRIF:15479729 GeneRIF:15512823 GeneRIF:15534117 GeneRIF:15583754 GeneRIF:15626731 GeneRIF:15657357 GeneRIF:15671442 GeneRIF:15677557 GeneRIF:15692064 GeneRIF:15692072 GeneRIF:15705883 GeneRIF:15725479 GeneRIF:15731173 GeneRIF:15731178 GeneRIF:15735670 GeneRIF:15753365 GeneRIF:15788896 GeneRIF:15878977 GeneRIF:15899516 GeneRIF:15902294 GeneRIF:15920166 GeneRIF:15933061 GeneRIF:15940250 GeneRIF:16002735 GeneRIF:16026644 GeneRIF:16030194 GeneRIF:16044163 GeneRIF:16091744 ICD9:203.0 ICD9:203.00 James Malone Kahler's disease MULT MYELM W/O REMISSION Multiple myeloma (clinical) Multiple myeloma (disorder) Multiple myeloma without mention of remission Multiple myeloma, morphology (morphologic abnormality) Multiple myeloma, no ICD-O subtype Multiple myeloma, no ICD-O subtype (morphologic abnormality) Myeloma, NOS Myelomatosis NCIt:C3242 Plasma Cell Myeloma Plasmacytic myeloma SNOMEDCT:109989006 SNOMEDCT:55921005 URI: http://www.ebi.ac.uk/cellline#multiple_myeloma [M]Plasma cell myeloma multiple myeloma myeloma endocrine system disease DOID:28 Disease of endocrine gland Disease, Endocrine Diseases of Endocrine System Disorder of endocrine gland Disorder of endocrine system Disorder of endocrine system (disorder) ENDOCRINE DIS ENDOCRINE DISORDER NOS ENDOCRINE DISORDERS ENDOCRINE SYSTEM DIS Endocrine Diseases and Manifestations Endocrine Disorder Endocrine diseases Endocrine disorder NOS (disorder) Endocrine disturbance Endocrine disturbance NOS Endocrine disturbance NOS (disorder) Endocrine gland disease NOS Endocrine gland disease NOS (disorder) Endocrinopathy Endocrinopathy, NOS GeneRIF:15132716 GeneRIF:15240634 GeneRIF:15296474 GeneRIF:15736104 Hormone abnormality Hormone abnormality (finding) Hormone disorders Hormone disturbance Hormone disturbance NOS ICD9:259.9 James Malone MSH:D004700 NCIt:C27565 NCIt:C3009 Non-Neoplastic Endocrine Disorder Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES. SNOMEDCT:190594008 SNOMEDCT:267475005 SNOMEDCT:267489000 SNOMEDCT:362969004 SNOMEDCT:84452004 System Diseases, Endocrine URI: http://www.ebi.ac.uk/cellline#endocrine_system_disease Unspecified endocrine disorder endocrine system disease endocrine system FMAID:9668 NCIt:C12705 URI: http://www.ebi.ac.uk/cellline#endocrine_system endocrine system RIKEN Cell Bank an organization that serves as a cell ine repository. Its website is: http://www.brc.riken.jp/lab/cell/english/. SS, YH,YL example to be eventually removed example to be eventually removed metadata complete Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. metadata complete organizational term PERSON:Alan Ruttenberg organizational term term created to ease viewing/sort terms for development purpose, and will not be included in a release ready for release Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." ready for release metadata incomplete Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. metadata incomplete uncurated Nothing done yet beyond assigning a unique class ID and proposing a preferred term. uncurated pending final vetting All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. pending final vetting to be replaced with external ontology term Alan Ruttenberg Terms with this status should eventually replaced with a term from another ontology. group:OBI to be replaced with external ontology term requires discussion A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. Alan Ruttenberg group:OBI requires discussion axiom holds for all times axiom holds for all times