]> Xiaolin Yang Yuqin Liu 2019-02-10 Jiangan Xie Hongjie Pan 2.1.162 Alex Ade Alexander Diehl Allen Xiang Stephan Schurer Caty Chung Matthew Brush Uma Vempati An ontology for the domain of cell lines and cell line cells Asiyah Yu Lin CLO: Cell Line Ontology Citation: Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer TC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y. CLO: The Cell Line Ontology. Journal of Biomedical Semantics. 2014, 5:37. doi:10.1186/2041-1480-5-37. PMID: 25852852. PMCID: PMC4387853. Daniel Cooper Helen Parkinson Hiroshi Masuya James Malone Jie Zheng OWL-DL Sirarat Sarntivijai Stefanie Seltmann The Cell Line Ontology (CLO) is a community-based ontology of cell lines. The CLO is developed to unify publicly available cell line entry data from multiple sources to a standardized logically defined format based on consensus design patterns. Yongqun "Oliver" He (YH) Yue Liu BFO OWL specification label BFO OWL specification label BFO OWL规范标签 BFO OWL规范标签 BFO OWL specification label Really of interest to developers only Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. BFO OWL规范标签 只对开发人员感兴趣 将本体中的实体关联到用于在代码中表示它的变量的名称，这些代码从lispy规范生成BFO OWL 文件。 BFO CLIF规范标签 BFO CLIF specification label BFO CLIF specification label BFO CLIF规范标签 Person:Alan Ruttenberg BFO CLIF specification label Person:Alan Ruttenberg Really of interest to developers only Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 BFO CLIF规范标签 只对开发人员感兴趣 将本体中的实体关联到用于在BFO2 CLIF规范中表示它的术语上。 Cell line LINCS ID 细胞系LINCS ID LINCS ID 细胞系LINCS ID An annotation property that represents an ID used in the NIH LINCS project. An annotation property that represents an LINCS ID of a cell line. Oliver He, Jiangan Xie, Jie Zheng 表示细胞系的LINCS ID的注释属性。 Oliver He, Jiangan Xie Oliver He, Jiangan Xie STR profile STR图谱 用于说明细胞系的STR图谱的注释属性。 An annotation property that specifies an STR profile of a cell line cell. An annotation property that specifies an STR profile of a cell line cell. Yongqun He Yongqun He PubChem AID An annotation property that represents a PubMed BioAssay Identifier accession number. Oliver He https://pubchem.ncbi.nlm.nih.gov/help.html problematic cell line annotation 问题细胞注释 An annotation property that describes the information of a problematic cell line. An annotation property that describes the information of a problematic cell line. Yongqun He Yongqun He 描述有问题的细胞系信息的注释属性。 cell line cell origin Oliver He An annotation property that describes the origin of a cell line. cell line cell feature An annotation property that describes the features of a cell line and cell line cell. Oliver He Known mutation annotation An annotation property that describes known mutation(s) about a cell. Oliver He Cell culture condition Resource ID 资源ID Hongjie Pan An annotation property that describes the Resource ID of the cells in National Infrastructure of Cell Line Resource. Hongjie Pan 描述“国家实验细胞资源共享平台”中细胞的资源ID的注释属性。 Chinese standardized name 中文名称 An annotation property that describes the English full name of a cell line. Hongjie Pan Hongjie Pan 描述细胞系中文名称的注释属性。 Morphological Characteristics 形态特征 描述细胞系形态特征的注释属性。 Hongjie Pan An annotation property that describes the morphological characteristics of a cell line. Hongjie Pan Growth Characteristics 生长特性 描述细胞系生长特性的注释属性。 An annotation property that describes the growth characteristics of a cell line. Hongjie Pan Hongjie Pan specific characteristics 特征特性 An annotation property that describes the general characteristics of a cell line. 描述细胞系基本特性的注释属性。 Hongjie Pan Hongjie Pan culture conditions 培养条件 Hongjie Pan 描述细胞系培养条件的注释属性。 Hongjie Pan An annotation property that describes the culture conditions of a cell line. passage situation 传代情况 An annotation property that describes the passage situation of a cell line. 描述细胞系传代情况的注释属性。 Hongjie Pan Hongjie Pan Frozen Storage Conditions 冻存条件 An annotation property that describes the frozen storage conditions of a cell line. Hongjie Pan Hongjie Pan 描述细胞系冷冻储存条件的注释属性。 mycoplasma detection 支原体检测 Hongjie Pan Hongjie Pan 描述支原体检测细胞系的注释属性。 An annotation property that describes the mycoplasma detection of a cell line. Isozyme Analysis 同工酶分析 Hongjie Pan 描述细胞系同工酶分析的注释属性。 An annotation property that describes the isozyme analysis of a cell line. Hongjie Pan chromosome style 染色体类型 描述细胞系染色体类型的注释属性。 An annotation property that describes the chromosome style of a cell line. Hongjie Pan Hongjie Pan application permission 使用权限 Hongjie Pan 描述细胞系使用权限的注释属性。 An annotation property that describes the application permission of a cell line. Cells in class A can be free distributed; cells in class B can be distributed with the permission of the donar; cells in Class C should be safety deposited Hongjie Pan picture 图片 Hongjie Pan 描述细胞系图片的注释属性。 An annotation property that describes the picture of a cell line. Hongjie Pan depository 保藏单位 描述细胞系保藏的注释属性。 An annotation property that describes the depository of a cell line. Hongjie Pan Hongjie Pan contacts 联系方式 Hongjie Pan 描述细胞系联系人信息的注释属性。 An annotation property that describes the contact information of a cell line. Hongjie Pan passage method 传代方法 An annotation property that describes the passage method of a cell line. 描述细胞系传代方法的注释属性。 Hongjie Pan Hongjie Pan 编辑首选术语 editor preferred term 编辑首选标签 editor preferred label 编辑首选术语~编辑首选标签 editor preferred term~editor preferred label editor preferred label editor preferred term editor preferred term~editor preferred label 编辑首选术语 编辑首选标签 editor preferred term editor preferred label editor preferred term editor preferred term~editor preferred label GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) editor preferred label 对于一类或属性的简洁的、有意义的、与人类友好的名称由本体开发商首选。 （美国英语） 编辑首选术语 编辑首选标签 用法示例 example of usage example of usage 用法示例 A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold. GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober example example of usage 例子 用法示例 短语描述一个类的名字应该如何使用。也可包括其他类型有助于直接理解类的语义的例子，如广为人知的类的原型子类或实例。虽然高水平的术语必不可少，对于低级别术语的示例（例如，Affymetrix HU133阵列）不 in branch in branch An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet. GROUP:OBI OBI_0000277 in branch has curation status 有管理状态 has curation status 有管理状态 OBI_0000281 PERSON:Alan Ruttenberg PERSON:Bill Bug PERSON:Melanie Courtot has curation status 有管理状态 definition textual definition textual definition 文本定义 definition definition textual definition 定义 定义 文本定义 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. definition GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. definition textual definition 2012-04-05: Barry Smith OBI的官方定义解释了一个类或属性的含义：'应该是亚里士多德式的，形式化和规范化的。可以用口语定义'是糟糕的。 您能解决这样的问题吗？ 解释关于类或属性的表达含义的必要和充分条件的陈述。 Alan Ruttenberg 您提出的定义是一个合理的备选，除非它很常见，没有给出必要和充分的条件。大多数情况下它们是必要的，偶尔是必要的，充分的或者仅仅仅充分的。它们通常使用不是自己定义的术语，因此它们实际上不能通过这些标准进行评估。 关于拟议定义的具体内容： 我们没有“含义”，或“表达”或“属性”的定义。对于在预期意义上的“参考”，我认为我们使用术语“指示”。对于'表达'，我认为我们和你的意思是符号，或标识符。对于“含义”，它不同于类和属性。对于类，我们希望文档能够让读者确定一个实体是否是该类的实例。对于属性，让我们的目标读者决定，给定一对潜在的关系，判断关系成立的断言正确与否。 “目标读者”部分表明我们也指定了我们期望的能够理解定义的人，并且概括了人类和计算机读者以包含文本和逻辑定义。 就我个人而言，我更愿意削弱对文档的定义，并指出什么是可取的。 我们还有一个悬而未决的问题，就是如何针对不同的受众定位不同的定义。临床读者阅读chebi需要来自受过化学训练的受众的不同类型的定义文档/定义，同样需要一个适合本体工作者的定义。 The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. textual definition OBI的官方定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 官方的定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 定义 editor note editor note 编者注 editor note 编者注 1 IAO:0000116 editor_note editor_note true uberon An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. GROUP:OBI:<http://purl.obfoundry.org/obo/obi> IAO:0000116 IAO:0000116 PERSON:Daniel Schober editor note editor_note editor_note editor_note editor_note uberon uberon 管理者注释用于其编辑器。它可能不包含在本体的出版版本中，所以它应该不包含最终用户了解本体所需的信息。 编者注 编辑_注释 编辑_注释 term editor definition editor 术语编辑者 definition editor term editor 术语编辑者 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115. 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115. GROUP:OBI:<http://purl.obolibrary.org/obo/obi> Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people PERSON:Daniel Schober definition editor term editor 20110707，MC：术语编辑和定义进行相应的修改。见http://code.google.com/p/information-artifact-ontology/issues/detail?id=115。 术语编辑者 输入文件中术语编辑者的名称。术语编辑者是有关术语的信息交汇点。术语编辑者可以是，但并不总是，定义的作者，这可能是由几个人完成 alternative term alternative term 替代术语 替代术语 An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent) GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober alternative term 一类或属性的替代名称，这意味着与所述首选名称同样的事物（语义上等价） 替代术语 definition source definition source 定义来源 定义来源 Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober definition source formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 定义来源 正式引用，例如在外部数据库中的标识符，用于表示/定义的属性源（S）。自由文本表示/为定义属性源（S）。实例：在2007年1月31日的作者姓名，URI，MeSH术语C04，PUBMEDID，维基uri 论OBO-讨论邮件-列表，请参阅http://bit.ly/hgm99w curator notes curator notes 管理者注释 curator note curator note curator notes 管理者注释 IAO:0000232 curator_notes curator_notes true uberon An administrative note of use for a curator but of no use for a user IAO:0000232 PERSON:Alan Ruttenberg curator note curator_notes curator_notes uberon 管理者_注释 管理者_注释 管理者注释 管理者注释对管理者有用对用户无用 引自 imported from imported from 引自 For external terms/classes, the ontology from which the term was imported GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Alan Ruttenberg PERSON:Melanie Courtot imported from 外部术语/类，术语引入的本体 引自 expand expression to expand expression to 说明 elucidation elucidation 说明 Person:Barry Smith Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms elucidation person:Alan Ruttenberg 在最高级别的本体中的原始术语如BFO是对我们理解现实最基本，以至于无法以非循环的方式来定义它们的术语。对于这些，因此，我们只能提供说明，通过例子和公理进行补充 说明 具有相关联的公理（nl） has associated axiom(nl) has associated axiom(nl) 具有相关联的公理（nl） An axiom associated with a term expressed using natural language Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(nl) 与一个使用自然语言表达的术语相关的公理 具有相关联的公理（nl） 具有相关联的公理（fol） has associated axiom(fol) has associated axiom(fol) 具有相关联的公理（fol） An axiom expressed in first order logic using CLIF syntax Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(fol) 使用CLIF语法在第一逻辑进行表达的公理 具有相关联的公理（fol） term replaced by code code code NHC0 Semantic_Type Conceptual Entity Semantic Type Semantic_Type Semantic_Type P106 In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS. The semantic type describes the sort of thing or category to which a concept belongs in the context of the UMLS semantic network. Display_Name Display Name Display Name Provides an alternative Preferred Name for use in some NCI systems. Display_Name Display_Name Conceptual Entity P107 Preferred_Name Preferred Term Conceptual Entity The word or phrase that NCI uses by preference to refer to the concept. P108 Preferred Name Preferred Name Preferred_Name Preferred_Name UMLS_CUI P207 Concept Unique Identifiers, or CUIs, are concept numbers assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept. UMLS_CUI UMLS_CUI Conceptual Entity UMLS CUI Contributing_Source This property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake. Contributing Source Conceptual Entity Contributing_Source P322 Contributing_Source ALT_DEFINITION Conceptual Entity [source] Definition ALT_DEFINITION ALT_DEFINITION P325 English language definitions of what a source other than NCI means by the concept. These are limited to 1024 characters. They include information about the definition's source in a form that can easily be interpreted by software. Legacy_Concept_Name A retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding. Legacy Concept Name Legacy Concept Name Conceptual Entity P366 Subsource P92 Currently used by MMHCC to identify the source of various mouse disease concepts. Subsource Conceptual Entity Subsource Subsource symbol from nomenclature authority the symbol assigned by the nomenclature authority Oliver He, Yue Liu full name from nomenclature authority the full name assigned by the nomenclature authority Oliver He, Yue Liu NCBI GeneID Oliver He, Yue Liu A GeneID in the NCBI Gene database NCBI LocusTag Oliver He, Yue Liu the NCBI LocusTag name of a gene gene map location the map location of a gene Oliver He, Yue Liu modification date a date of content modification Oliver He, Yue Liu organism NCBITaxon ID The NCBITaxon ontology ID of an organism. Oliver He, Yue Liu chromosome ID of gene A chromosome ID where a gene is located. Oliver He type of gene Oliver He an annotation property that specifies the type of a gene nomenclature status an annotation property that specifies a nomenclature status Oliver He has GO association YH: use the convention: GO_ID (EC: xx; Qualifier: xx; PMID: xxxxx;) where GO_ID is a GO ID, EC is the Evidence Code, Qualifier is a specific association type, and PMID is a PubMed ID of a paper that supports the gene-GO association. an annotation property that shows the GO information associated with a specific gene. Yongqun He has PubMed association YH: use the format: PMID: pmid1, pmid2, ... where pmid1 and pmid2 are specfic PubMed IDs (PMIDs). Yongqun He An annotation property that represents a gene's association with PubMed publication(s). temporal interpretation temporal interpretation https://code.google.com/p/obo-relations/wiki/ROAndTime https://github.com/oborel/obo-relations/wiki/ROAndTime An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context. temporal interpretation dubious_for_taxon dubious_for_taxon 可疑_于_分类 dubious_for_taxon 可疑_于_分类 RO:0002174 S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T. dubious_for_taxon dubious_for_taxon this relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take time to resolve. Example: metencephalon in teleost true true uberon RO:0002174 S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T. dubious_for_taxon dubious_for_taxon this relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take time to resolve. Example: metencephalon in teleost uberon S可疑_于_分类 T如果在T的任何实例中可能找不到S的实例， 可疑_于_分类 可疑_于_分类 这种关系缺乏一个强有力的逻辑解释，但可以以理想状态用在不_在_分类中，其中有必要说明该类的定义对于所考虑的分类群来说过于严格，但放置一个不_在_分类链接会导致链的不一致，需要时间来解决。例如：后脑硬骨 present_in_taxon present_in_taxon 存在_于_分类 present_in_taxon 存在_于_分类 RO:0002175 S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S applicable for taxon present_in_taxon present_in_taxon true true uberon RO:0002175 S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S applicable for taxon present_in_taxon present_in_taxon uberon S存在_于_分类 T如果T的某个实例有一些S，这并不意味着T的所有实例都有S - 它可能只是某些生命阶段或者性别具有S 存在_于_分类 存在_于_分类 适用于分类单元 external_definition external_definition external_definition 外部_定义 外部_定义 An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000001 external_definition external_definition true uberon An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000001 external_definition external_definition uberon 外部_定义 外部_定义 对外部来源未修改的类的替代文本定义。这个定义可能被用来为新类推导出一个广义的定义。 这个注释的属性可以用从外部本体如IAO注解属性替换 axiom_lost_from_external_ontology axiom_lost_from_external_ontology axiom_lost_from_external_ontology 公理_丢失_自_外部_本体 公理_丢失_自_外部_本体 A textual description of an axiom loss in this ontology compared to an external ontology. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000002 axiom_lost_from_external_ontology axiom_lost_from_external_ontology true uberon A textual description of an axiom loss in this ontology compared to an external ontology. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000002 axiom_lost_from_external_ontology axiom_lost_from_external_ontology uberon 与外部本体相比，本本体中的公理缺失的文本描述。 公理_丢失_自_外部_本体 公理_丢失_自_外部_本体 这个注释的属性可以用从外部本体如IAO注解属性替换 homology_notes homology_notes 同源_注释 homology_notes 同源_注释 Notes on the homology status of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000003 homology_notes homology_notes true uberon Notes on the homology status of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000003 homology_notes homology_notes uberon 关于这个类的同源性状态的注释。 同源_注释 同源_注释 这个注释的属性可以用从外部本体如IAO注解属性替换 external_comment external_comment An alternate comment for a class taken unmodified from an external source. Note that obo format only allows a single comment for a class, and does not provide a structured means of adding provenance info. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000005 external_comment external_comment true uberon implements_design_pattern implements_design_pattern UBPROP:0000006 implements_design_pattern implements_design_pattern true uberon has_relational_adjective has_relational_adjective has_relational_adjective 有_关系_形容词 有_关系_形容词 UBPROP:0000007 Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. has_relational_adjective has_relational_adjective true uberon UBPROP:0000007 Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. has_relational_adjective has_relational_adjective uberon 有_关系的_形容词 有_关系的_形容词 用于将类连接到其标签的形容词形式。例如，具有标签“肠”的类可能具有关系形容词“肠的”。 taxon_notes taxon_notes 分类_注释 taxon_notes 分类_注释 Notes on the how instances of this class vary across species. UBPROP:0000008 taxon_notes taxon_notes true uberon Notes on the how instances of this class vary across species. UBPROP:0000008 taxon_notes taxon_notes uberon 关于这个类的实例在不同物种间的差异的注释。 分类_注释 分类_注释 function_notes function_notes function_notes 功能_注释 功能_注释 Notes on the evolved function of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000009 function_notes function_notes true uberon Notes on the evolved function of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000009 function_notes function_notes uberon 关于这个类的实例的演变函数的注释。 功能_注释 功能_注释 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 structure_notes 结构_注释 structure_notes structure_notes 结构_注释 Notes on the structure, composition or histology of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000010 structure_notes structure_notes true uberon Notes on the structure, composition or histology of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000010 structure_notes structure_notes uberon 关于这个类的实例的结构、组成或组织学的注释。 结构_注释 结构_注释 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 development_notes 发育_注释 development_notes development_notes 发育_注释 Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 development_notes development_notes true uberon Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 development_notes development_notes uberon 关于这个类的实例的个体发育的注释。 发育_注释 发育_注释 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 external_ontology_notes external_ontology_notes external_ontology_notes 外部_本体_注释 外部_本体_注释 Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 external_ontology_notes external_ontology_notes true uberon Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 external_ontology_notes external_ontology_notes uberon 外部_本体_注释 外部_本体_注释 注意在其他本体中如何表示相似或等价的类。 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 terminology_notes terminology_notes Notes on how lexical conventions regarding this class, in particular any issues that may arise due to homonyny or synonymy. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000013 terminology_notes terminology_notes true uberon fma_set_term fma_设定_术语 fma_set_term fma_set_term fma_设定_术语 FMA has terms like 'set of X'. In general we do not include set-of terms in uberon, but provide a mapping between the singular form and the FMA set term UBPROP:0000202 fma_set_term fma_set_term true uberon FMA has terms like 'set of X'. In general we do not include set-of terms in uberon, but provide a mapping between the singular form and the FMA set term UBPROP:0000202 fma_set_term fma_set_term uberon FMA具有像'一组X'这样的术语。一般来说，我们不包含uberon中的集合项，但提供单数形式和FMA集合项之间的映射 fma_设定_术语 fma_设定_术语 has_rank has_rank A metadata relation between a class and its taxonomic rank (eg species, family) ncbi_taxonomy ncbi_taxonomy Title Title Typically, a Title will be a name by which the resource is formally known. A name given to the resource. contributor 贡献者 Contributor Contributor contributor Contributor 贡献者 dc-contributor dc-contributor true uberon dc-contributor dc-contributor uberon An entity responsible for making contributions to the content of the resource. Examples of a Contributor include a person, an organisation, or a service. Typically, the name of a Contributor should be used to indicate the entity. 一个实体应该有助于 资源的内容 贡献者的例子包括一个人，一个 组织或者一个服务。 典型地， 一个贡献者的名字 应该用于指示这个实体. dc-贡献者 dc-贡献者 Creator Creator An entity primarily responsible for making the content of the resource. Examples of a Creator include a person, an organisation, or a service. Typically, the name of a Creator should be used to indicate the entity. Date Date A date associated with an event in the life cycle of the resource. Typically, Date will be associated with the creation or availability of the resource. Recommended best practice for encoding the date value is defined in a profile of ISO 8601 [W3CDTF] and follows the YYYY-MM-DD format. 描述 Description Description Description 描述 An account of the content of the resource. Description may include but is not limited to: an abstract, table of contents, reference to a graphical representation of content or a free-text account of the content. 描述应该包含但不限于一个摘要， 内容表格, 内容的图形表示 或内容的自由文本描述 资源内容的说明。 Format Format The physical or digital manifestation of the resource. Typically, Format may include the media-type or dimensions of the resource. Format may be used to determine the software, hardware or other equipment needed to display or operate the resource. Examples of dimensions include size and duration. Recommended best practice is to select a value from a controlled vocabulary (for example, the list of Internet Media Types [MIME] defining computer media formats). Source Source A reference to a resource from which the present resource is derived. The present resource may be derived from the Source resource in whole or in part. Recommended best practice is to reference the resource by means of a string or number conforming to a formal identification system. Subject and Keywords Subject and Keywords The topic of the content of the resource. Typically, a Subject will be expressed as keywords, key phrases or classification codes that describe a topic of the resource. Recommended best practice is to select a value from a controlled vocabulary or formal classification scheme. Title Title Typically, a Title will be a name by which the resource is formally known. A name given to the resource. consider has_alternative_id 有_可替代的_id has_alternative_id has_alternative_id 有_可替代的_id has_broad_synonym has_broad_synonym has_broad_synonym 有_广义的_同义词 有_广义的_同义词 database_cross_reference 数据库_交叉_引用 database_cross_reference database_cross_reference 数据库_交叉_引用 has_exact_synonym has_exact_synonym has_exact_synonym 有_精确的_同义词 有_精确的_同义词 has_narrow_synonym has_narrow_synonym has_narrow_synonym 有_狭义的_同义词 有_狭义的_同义词 has_obo_namespace has_obo_namespace has_obo_namespace 有_obo_命名空间 有_obo_命名空间 has_related_synonym has_related_synonym 有_相关的_同义词 has_related_synonym 有_相关的_同义词 in_subset 在_子集 in_subset in_subset 在_子集 shorthand shorthand shorthand 标签 label label label depicted_by depicted_by 由_描述 part of part_of part of part_of Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. http://www.obofoundry.org/ro/#OBO_REL:part_of Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. a core relation that holds between a part and its whole is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) part_of this day is part of this year (occurrent parthood) has part has part has_part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. a core relation that holds between a whole and its part has part has_part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) inheres in at all times realized in Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) is realized by realized in realized_in this disease is realized in this disease course this fragility is realized in this shattering this investigator role is realized in this investigation realizes Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process realizes this disease course realizes this disease this investigation realizes this investigator role this shattering realizes this fragility to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) participates_in concretized by at some time occurs in located_in located_in occupies spatial region at some time has_quality has_quality http://www.ebi.ac.uk/efo/has_quality exists at has occurrent part has spatial occupant at some time part of occurrent occupies temporal region has temporal occupant has disposition at all times specifically depends on at some time part of continuant at some time has continuant part at some time part of continuant at all times that whole exists has continuant part at all times that part exists derives from patient having disease In most cases, the patient in the relation is used to refer human patient. However, an animal patient (or veterinary patient) can also be referred. a 'derives from' object property between an entity (in CLO case, cell line) and a disease in a patient where the entity is derived from some cell in the patient who has the disease. This is a short cut relation that represents: 'derived from' some (cell and ('part of' some 'organism' and ('has disease' some disease))) Yongqun He has disease Jie Zheng, Yongqun He, Yu Lin, Allen Xiang This is a shortcut relation. It is equivalent to: participates_in some 'disease couse' and realizes some disease a disease disposition has been realized by a bearer. is in cell line repository an object property that specifies a cell line repository for a specifc cell line. SS, YH, UV, SS is disease model for an object property that represents a relation between a cell line cell and a disease. Asiyah Yu Lin, Yongqun He This object property is largely equivalent to the previous term 'is model for' (http://www.ebi.ac.uk/cellline#is_model_for). transfected to express an object property that represents a relation between a cell line cell and a protein where the cell line cell is genetically transfected to stably express a foreign protein in the cell line cell. Oliver He, Asiyah Yu Lin HeLa ICRP cell is transfected to express a Initiator caspase reporter protein (IC-RP) derived from organism a 'cell line cell derives from' object property between an entity (e.g., cell line cell in CLO) and an organism where the cell line cell is derived from some cell from the organism. In CLO, this is a short cut relation that represents: 'derived from' some (cell and ('part of' some organism)) derived from anatomic part a 'derives from' object property between an entity (i.e., cell line cell in CLO) and an anatomic part from an organism where the cell line cell is derived from some cell in the anatomic part (e.g., tissue or organ). The anatomic part is typically defined by UBERON in CLO. in CLO, this is a short cut relation that represents: 'derived from' some (cell and ('part of' some 'anatomic part')) derived from cell derived from cell line cell line cell derived from a 'derived from' object property that specifies the domain of the property is a cell line cell. Oliver He cell line cell derived from anatomical part a 'cell line cell derives from' object property between a cell line cell and an anatomic part from an organism where the cell line cell is derived from some cell in the tissue. The anatomic part is typically defined by UBERON in CLO. This is a short cut relation that represents: 'derived from' some (cell and ('part of' some 'anatomic part')) Oliver He cell line cell derived from organism Oliver He a 'cell line cell derives from' object property between a cell line cell and an organism where the cell line cell is derived from some cell from the organism. This is a short cut relation that represents: 'derived from' some (cell and ('part of' some organism)) induced by cell culture reagent overexpresses gene is about 7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of "mentions" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered "about" are predications - "The only person who knows the answer is sitting beside me" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic. Smith, Ceusters, Ruttenberg, 2000 years of philosophy This document is about information artifacts and their representations is about is_about is a (currently) primitive relation that relates an information artifact to an entity. person:Alan Ruttenberg mentions 7/6/2009 Alan Ruttenberg. P4 RC1 munges our GCI so remove it for now: mentions some entity equivalentTo has_part some ('generically denotes' some entity) 7/6/2009 Alan Ruttenberg: Add this relation following conversation with Jonathan Rees that N&S GCI for is_about was too strong. Really it was simply sufficient. To effect this change we introduce this relation, which is subproperty of is_about, and have previous GCI use this relation "mentions" in it's (logical) definition An information artifact IA mentions an entity E exactly when it has a component/part that denotes E PERSON: Jonathan Rees Person: Alan Ruttenberg has_specified_input 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works. PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Coutot A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_input see is_input_of example_of_usage is_specified_input_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Alan Ruttenberg is_specified_input_of some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay has_specified_output PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Courtot A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_output is_manufactured_by Alan Ruttenberg Liju Fan c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this. has_make has_manufacturer http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities) is_manufactured_by is_specified_output_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Alan Ruttenberg is_specified_output_of achieves_planned_objective achieves_planned_objective A cell sorting process achieves the objective specification 'material separation objective' BP, AR, PPPB branch PPPB branch derived This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process. achieves_planned_objective modified according to email thread from 1/23/09 in accordince with DT and PPPB branch has grain has grain PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349 has grain the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car. Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form PERSON: Alan Ruttenberg objective_achieved_by This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process. objective_achieved_by OBI OBI is genome of organism is gene of organism inheres in A dependent inheres in its bearer at all times for which the dependent exists. a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence inheres in inheres_in this fragility inheres in this vase this red color inheres in this apple bearer of A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence bearer of bearer_of is bearer of this apple is bearer of this red color this vase is bearer of this fragility participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process participates in participates_in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation has participant Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. a relation between a process and a continuant, in which the continuant is somehow involved in the process has participant http://www.obofoundry.org/ro/#OBO_REL:has_participant has_participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) concretizes A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant). A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant. An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process). concretizes has function A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists. a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence has function has_function this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function) has_quality derives_from derives from derives_from This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'. a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives from derives_from this cell derives from this parent cell (cell division) this nucleus derives from this parent nucleus (nuclear division) derives into This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'. a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives into derives_into this parent cell derives into this cell (cell division) this parent nucleus derives into this nucleus (nuclear division) located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location ends after David Osumi-Sutherland X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) happens during X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y)) d during David Osumi-Sutherland ends during David Osumi-Sutherland o overlaps X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). has plasma membrane part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. overlaps http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) x overlaps y if and only if there exists some z such that x has part z and z part of y only_in_taxon develops_from develops from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y develops into capable of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. capable of part of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. has output Chris Mungall p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p. produces developmentally preceded by Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p developmentally succeeded by Inverse of developmentally preceded by expresses Chris Mungall Inverse of 'expressed in' mereotopologically related to A mereological relationship or a topological relationship Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) functionally related to output_of has developmental potential involving x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). has potential to develop into x has the potential to develop into y iff x develops into y or if x is capable of developing into y has potential to directly develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y causally related to This relation groups causal relations between material entities and causal relations between processes existence starts during existence starts during RO:0002488 Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s. begins_to_exist_during existence_starts_during existence_starts_during uberon existence starts with RO:0002489 Relation between continuant and occurrent, such that c comes into existence at the start of p. existence_starts_with existence_starts_with uberon immediate transformation of direct_transformation_of immediately transforms from existence starts during or after RO:0002496 existence_starts_during_or_after existence_starts_during_or_after uberon causal agent in A relationship between a material entity and a process where the material entity has some causal role that influences the process causal relation between material entity and a process A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. has causal agent Inverse of 'causal agent in' related via dependence to A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes. produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. Melissa Haendel Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue. a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. produced by a produced_by b iff some process that occurs_in b has_output a. has_completed has_high_plasma_membrane_amount has_high_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). has_low_plasma_membrane_amount has_low_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). has_not_completed lacks_part lacks_part http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y lacks_plasma_membrane_part lacks_plasma_membrane_part http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) has_gene_template lacks_part has expression is model for a relation that indicates a cell line cell is a model for studying a disease. Domain: a cell line cell Range: a disease. has_disease_location has_disease_location contained_in peripheral vein peripheral vein 外周静脉 SNOMEDID: T-48097 URI: http://www.ebi.ac.uk/cellline#Structure_of_peripheral_vein SNOMEDID: T-48097 URI: http://www.ebi.ac.uk/cellline#Structure_of_peripheral_vein amniotic fluid Aqua Amnii Liquor Amnii The fluid within the amniotic cavity which surrounds and protects the developing embryo. (NCI)CDISC Amniotic cavity fluid which is produced by the AMNION and fetal lungs and kidneys.MSH2001 The fluid within the amniotic cavity which surrounds and protects the developing embryo. It is initially produced by the amnion and then later by the lungs and kidneys. The amount at term normally varies from 500 to 2000 ml. UMLS: C0002638 URI: http://www.ebi.ac.uk/cellline#Amniotic_fluid Waters (Amniotic Fluid) amniotic sac UMLS: C0883994 URI: http://www.ebi.ac.uk/cellline#Amniotic_Sac chorionic villus Tiny vascular tissue projections from the membranous sac that surrounds the embryo. UMLS: C0008508 URI: http://www.ebi.ac.uk/cellline#Chorionic_Villus embryonic fluid Embryonic Fluids Embryonic Tissue, Fluids, Secretions UMLS: C1516820 URI: http://www.ebi.ac.uk/cellline#Embryonic_Fluid gonad gonad 性腺 A reproductive system organ that produces and releases either sperm (testis) or eggs (ovary). Gonadal Gonads The part of the reproductive system that produces and releases eggs (ovaries) or sperm (testicles/testes).NCI-GLOSS UMLS: C0018067 URI: http://www.ebi.ac.uk/cellline#Organ A reproductive system organ that produces and releases either sperm (testis) or eggs (ovary). Gonadal Gonads The part of the reproductive system that produces and releases eggs (ovaries) or sperm (testicles/testes).NCI-GLOSS UMLS: C0018067 URI: http://www.ebi.ac.uk/cellline#Organ 产生和释放卵子（卵巢）或精子（睾丸）的生殖系统的一部分.NCI-GLOSS 产生和释放精子（睾丸）或卵子（卵巢）的生殖系统器官。 iliac vein A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.MSH2001 UMLS: C0020888 URI: http://www.ebi.ac.uk/cellline#Iliac_Vein rhomboid Rhomboid (body structure) Rhomboid - muscle UMLS: C1260952 UMLS: T-13606 URI: http://www.ebi.ac.uk/cellline#Rhomboid entity 实体 entity BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 实体 An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) Entity Entity Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf Julius Caesar Verdi’s Requiem 实体 entity entity the Second World War your body mass index BFO 2参考：在经验性总结分析的所有领域，我们遇到两种一般术语。首先是指共相或类型的一般术语：animaltuberculosissurgical proceduredisease其次，是用来指以下实例组的一般术语，这些实例组实例化一个给定共性但对应于该共相的任何子共相的扩展，因为没有实体的内在本质讨论因为他们-只有他们-被视为属于给定的群体。例子是：对斯德哥尔摩病人进行的周三手术过程中诊断出结核分枝杆菌而购买的动物，被确定为临床试验的候选人＃2056-555根据莱昂纳多·达·芬奇（Leonardo da Vinci）条款制定的656-PPV表格的签名人。这些术语代表所谓的“专业化'[81 一个实体是存在或已经存在或将存在的任何事物。 （BFO2公理标签参考：[001-001]） 你的身体质量指数 凯撒大帝 威尔第年代安魂曲 实体 实体不具有闭合公理，因为子类不一定丧失所有可能性。例如，Werner Ceusters的“现实的部分”包括4类，实体（当BFO构造它们时）、普遍性、配置和关系。这是一个开放性的问题，即在BFO中所解释的实体是否会在某个时候也包含这些其他的现实部分。参见，例如“如何完全追踪所有事物”在http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf 第二次世界大战 continuant 常体 Continuant (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] continuant (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. continuant continuant if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) 常体 常体 BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) BFO 2参考：持续实体是可以被分割的实体，只能沿着空间维度分割成部分，例如产生您的桌子的部分，我们称之为它的腿、顶部、指甲。 “我的桌子从窗户延伸到门口。它有空间部分，可以在空间切成两半。不过，就时间而言，一个事物是连续的。“[60，p。 240 一个在任何时候都存在的实体，它持续存在，在维持其特性的同时且没有暂时的部分。 一个常体是一个持续、持久或持续存在且同时保持其身份的实体。 （BFO2中的公理标签参考：[008-002]） 如果b是一个常体，并且如果对于某个t，c在t时刻具有_常体_部分b，则c是一个常体。 （BFO2公理标签参考：[126-001]） 如果b是一个常体，并且如果，对于某个t，c是在t时刻的b的常体_部分，则c是一个常体。 （BFO2公理标签参考：[009-002]） 如果b是物质实体，则在b存在期间有一些时间间隔（以下称为一维时间区域）。 （BFO2公理标签：[011-002]） 常体 常体不具有闭合公理，因为子类不一定丧失所有可能性。例如，在涉及引入一些Ceuster的实体的其他部分的扩展中，提出了普遍性是否是连续性的问题 occurrent 行体 (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] 行体 (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] An entity that has temporal parts and that happens, unfolds or develops through time. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region Occurrent Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) Occurrent Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. 行体 BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) occurrent occurrent BFO 2参考：不是时间或时空区域的每一个行体都是依赖于某个独立的且不是空间区域的常体 BFO 2参考：每个过程之间获得的s-依赖和它的参与者从某种意义上说，必要的时候，除非这些或那些参与者也存在，否则这个过程是不可能存在的。一个过程可能有一系列参与者在其展开的不同阶段。因此在足球比赛过程中的不同时间场上可能会有不同的球员;但整个游戏的过程依赖于所有这些玩家。这个过程的一些暂时的部分将只s-依赖_于一些玩家。 Simons使用不同的术语来表示发生在不同区域的行体关系：通过'spn [e]'表示给定occurrent e的时空位置。并称这个区域为跨度。我们可以说一个行体在它的跨度内，在任何一个较大的地区，覆盖了所有较小的地区。现在假设我们已经固定了一个参考框架，以便我们不仅可以谈及时空，而且可以谈及空间区域（地点）和时间区域（时间）。一个行体的（相对于一个参考框架）的延伸是它正好占据的空间，而它的拼写同样也是它正好占据的时间。我们写“spr [e]”和“spl [e]”。分别为e的延伸和拼写，省略框架的提及。 occurrent 一个行体是一个在时间上展开的实体，或者是一个实体的瞬时边界（例如一个起点或终点），或者是一个时空或时空区域，其中这样一个实体占据_时空_区域或占据_空间_区域的。 （BFO2公理标签参考：[077-002]） 具有时间部分且随时间发生、展开或发展的实体。 如果b是具有时间部分的实体，则b是一个行体实体。 （BFO2公理标签参考：[079-001]） 每一个行体都会占据_时空_区域一些时空区域。 （BFO2公理标签参考：[108-001]） 行体 行体并不具有闭合公理，因为子类不一定丧失所有可能性。一个例子是一个进程和另一个进程的进程边界的总和。 independent continuant 独立常体 IndependentContinuant (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] 独立常体(IndependentContinuant) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) IndependentContinuant ic a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) ic independent continuant the bottom right portion of a human torso the interior of your mouth b是一个独立常体= Def. b是一个常体，使得在t时刻不存在c，也不存在t，从而在t时刻b s-依赖_于c。 （BFO2公理标签参考：[017-002]） 一个分子 一个原子 一个心脏 一个有机体 一个空间区域 一个管弦乐队。 一把椅子 一条腿 人体躯干的右下部分 你的嘴巴内部 对于任何独立常体b和任何时刻t，都有一些空间区域r，使得b在t时刻位_于r处。 （BFO2公理标签参考：[134-001]） 对于在其生命周期中的每个时间区域内每个独立的常体b和时间t，在t期间存在s-依赖_于b的实体。 （BFO2公理标签参考：[018-002]） 常体是质量和可实现实体的载体，其中其他实体在其中并且本身不能在任何地方存在。 独立常体(Independent Continuant) spatial region true true (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] s-region BFO 2 Reference: Spatial regions do not participate in processes. Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. SpatialRegion (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) temporal region 时间区域 true true (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) TemporalRegion t-region (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional process 过程 (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] BFO:0000015 Process a process of cell-division, \ a beating of the heart a process of meiosis p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) process (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. process process the course of a disease the life of an organism your process of aging. 一个减数分裂的过程 一个生物体的生命 一个细胞分裂的过程，\一个跳动的心脏 过程 Process BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) a process of sleeping bfo the flight of a bird p是一个进程= Def. p是一个常体，其具有时间适当的部分且对于某个时间t，p s-依赖_于t时刻的一些物质实体。 （BFO2公理标签参考：[083-003]） 一只鸟的飞行 过程 BFO 2参考文献：相比在行体领域的情况，自然单位在独立常体领域的存在更普遍。因此这里没有对象的对等物。在BFO 1.0'过程'中充当了这样一个对等物。在BFO 2.0中，“过程”相当于“物质实体”的对等物。那些自然的-与工程设计相对比，这里的意思是：在现实领域中确实存在的故意执行-单位通常是寄生于常体侧存在的自然单位，或者它们本质上是允许的。因此，我们可以计算生命;我们可以算足球比赛;我们可以计算在实验或化学制造中进行的化学反应。我们不能计算如发生在昆虫交配行为中的过程。即使自然单位是可识别的，例如周期性过程的周期，例如跳动心脏或生物体的睡眠/觉醒周期，过程在讨论中形成一个没有我们发现的那种不连续性（时间间隔）的序列，在这种不连续性中，如台球或斑马鱼或行星被明确的空间差距分开。有机体的生命是过程单元，但是它们也是从其他先前的过程（如受精）中连续地展开，然后展开连续的一系列后期过程，例如死后衰变。过程界限的清晰例子几乎总是属于法定类型（午夜，手术室宣布的死亡时间或者死亡证明，战争状态的开始） 一个常体，其具有时间适当的部分且对于某个时间t，p s-依赖_于t时刻的一些物质实体。 一个睡眠的过程 你的老化过程。 疾病的过程 过程 disposition 倾向 Disposition (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] disposition (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] 倾向 (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type [89 BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. Disposition children are innately disposed to categorize objects in certain ways. 倾向 If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) an atom of element X has the disposition to decay to an atom of element Y b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) certain people have a predisposition to colon cancer disposition disposition the cell wall is disposed to filter chemicals in endocitosis and exocitosis the cell wall is disposed to filter chemicals in endocytosis and exocytosis BFO 2参考：倾向存在于强度连续体中。只有一小部分触发事件才能实现较弱的倾向形式。这些形式出现在相当数量的类似案例中。 b是倾向方式：b是可实现的实体； b的持有人是一些物质实体； b是这样的，如果它不复存在，那么它的持有人发生了物理变化； b的实现发生在且因为这个持有者处于一些特殊的物理环境中；这种实现是由于持有者的物理构成而发生的。 （BFO2公理标签参考：[062-002]） 倾向 元素X的原子具有衰减到元素Y的原子的倾向 如果b是一个可实现的实体，那么对于存在b的所有t时刻，b s-依赖_于t时刻的一个物质实体。 （BFO2公理标签参考：[063-002]） 孩子天生就倾向于以特定的方式对物体进行分类。 某些人有结肠癌的倾向 细胞壁被设置为过滤内吞作用和胞吐作用中的化学物质 realizable entity 可实现实体 (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] 可实现实体(RealizableEntity) A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) RealizableEntity realizable (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] realizable realizable entity the role of being a doctor 你的生殖器官的功能 你的血液的凝结倾向 可实现的 (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] RealizableEntity To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of this boundary to delineate where Utah and Colorado meet 一个特定依赖性常体，在常体实体中存在，并且在每个实体或一组实体中都不会全部展现出来。可实现实体的展示或实现是在特定情况下发生的特定表现、功能或过程。 作为医生的角色 可实现实体 所有可实现依赖常体都有独立常体，这些独立常体不是空间区域作为承载。 （BFO2公理标签参考：[060-002]） 要说b是一个可实现实体，就是说b是一个特定依赖性常体，它存在于某些依赖常体中，这个连续体不是一个空间区域，而是一个在相关类型的过程中实现的类型实例。 （BFO2公理标签参考：[058-002]） 这个边界角色描绘了犹他州和科罗拉多州的交汇点 这块金属的导电倾向。 quality 性质 性质 (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] 性质 Quality Quality a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) bfo quality (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] BFO:0000019 If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) quality quality the ambient temperature of this portion of air the color of a tomato the length of the circumference of your waist the mass of this piece of gold. the shape of your nose the shape of your nostril 你的腰围的长度 你的鼻子的形状 你的鼻孔的形状 如果一个实体在任何时候都存在一个性质，那么在它存在的每个时间它就是一个性质。 （BFO2公理标签参考：[105-001]） 性质 番茄的颜色 质量是一个特定依赖性常体，与角色和性格相反，不需要任何进一步的过程才能实现。 （BFO2公理标签参考：[055-001]） 这块黄金的质量。 这部分空气的环境温度 specifically dependent continuant 特定依赖性常体 (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. sdc (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] SpecificallyDependentContinuant 特定依赖性常体(SpecificallyDependentContinuant) Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key SpecificallyDependentContinuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. sdc specifically dependent continuant the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella b是一个关系特定依赖性常体 = Def. b是特定依赖性常体并且有n &gt;1个独立常体c1，... cn不是空间区域且是这样的，即对于全部1个 i&lt;j n，ci和cj没有共同的部分，对于每个1 i n，在b存在的过程中每个时间t，b s-依赖_于 ci（BFO2中的公理标号：[131-004]） b是一个特定依赖性常体 = Def. b是一个常体& 存在一些独立常体c，c不是一个空间区域且是这样的，在b的存在过程地每个时间t，b s-依赖_于c。 （BFO2公理标签参考：[050-003]） 一个在其他实体中存在或由其他实体承担的常体。 A的每个实例都需要一些特定的B实例，这些B实例必须始终相同。 交互特定依赖性常体：这个键的功能打开这个锁和这个锁的相互依赖的配置：被这个键打开 作为医生的角色 关系独立常体（对个载体）：约翰对玛丽的爱，约翰与这座雕像之间的所有关系，以及约翰与他的下属之间的权力关系。 具体而言，相关常体不具有闭合公理，因为子类不一定丧失所有可能性。我们不确定在这里会发生什么，但是会有如什么是承诺，义务等等的问题。 在它中心的一块四分熟烤菲力牛排的粉色 局部特定依赖性常体：这个番茄的性质 捕食者角色和猎物角色的相互依赖由两个生物体在给定的相互作用中扮演 特定依赖性常体 质子供体和受体在化学反应中的相互依赖[79 这个洞的形状。 这条鱼的腐烂倾向 这部分马苏里拉奶酪的气味 这颗心的功能：抽血 role 角色 A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. Role role 角色 (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. 角色 John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. Role b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) role role the priest role the role of a boundary to demarcate two neighboring administrative territories the role of a building in serving as a military target the role of a stone in marking a property boundary the role of subject in a clinical trial the student role BFO 2参考：非刚性共相的一个主要例子涉及角色，及为相应的管理目的而开发的本体可以完全由这类实体的代表组成。因此，“教授”的定义如下，b为t时的教授实例=Def.有一些c，c为教授角色的实例 & 在t时刻，c存在_于b，表示非刚性共相，所以还要做“护士”、“学生”、“上校”、“纳税人”等等。 （这些术语在哲学术语中都是阶段排序的。）通过在定义中使用角色术语，我们可以为这些实体创建一个BFO一致性处理，而这些实体根据这个事实，即一个教授实例可能同时是工会成员，没有教授角色类型的实例也是（在任何时候）工会成员角色类型的实例（任何时候任何颜色类型的实例都是长度类型的实例）。如果就业岗位的本体应该根据上述模式的角色来定义，这就使得本体能够正确地处理这样一个事实，即个人在生命的某个阶段只实例化相应的共相-教授、中士、护士。 b是一个角色意味着：b是可实现实体 & b的存在是因为在某些特定的物理、社会或制度环境中存在一些单一的承载者，在这种环境下，承载者不必是“ b不是这样的，如果它不复存在，那么承载者的物理组成就会改变。 （BFO2公理标签参考：[061-001]） 一个可实现实体，它的表现会带来某种结果或结局，而这种结果或结局对于一个常体来说并不是必不可少的，因为它是一种事物，但它可以在某种自然的，社会的或制度的环境中，被这种常体所服务或参与。 作为军事目标的建筑物的角色 学生角色 患者在临床试验中的作用 牧师的角色 石头在标记一个属性边界中的角色 约翰对玛丽的丈夫角色依赖于玛丽对约翰的妻子角色，二者都依赖于由约翰和玛丽组成的对象集合，其中包括约翰和玛丽作为成员部分通过婚姻关系性质而成为一体。 角色 边界划分两个邻近的行政区域的角色 fiat object part 虚拟对象部分 BFO:0000024 bfo three-dimensional spatial region ThreeDimensionalSpatialRegion 3d-s-region (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) a cube-shaped region of space a sphere-shaped region of space, object 客体 BFO:0000030 bfo generically dependent continuant 普遍依赖性常体 gdc GenericallyDependentContinuant (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] 普遍依赖性常体(GenericallyDependentContinuant) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. GenericallyDependentContinuant The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) gdc generically dependent continuant the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. b是一个普遍依赖性常体 = Def. b是g-依赖_于一个或多个其他实体的常体。 （BFO2公理标签参考：[074-001]） 依赖于一个或另一个独立常体承载者的常体。对于A的每个实例都需要某个（一个独立常体类型）B的实例，但是B实例服务的对象可能会随时变化。 在您的笔记本电脑上的PDF文件，这个PDF文件是我的笔记本电脑上的副本 数据库中的条目是在硬盘驱动器中实例化为性质实例的模式。数据库本身就是这些模式的集合。在创建数据库时，您将创建普遍依赖性常体类型数据库的特定实例。数据库中的每个条目都是普遍依赖性常体类型IAO的一个实例：信息内容实体。 普遍依赖性常体 这个蛋白质分子的序列;在该蛋白质分子中是其序列的拷贝。 function (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] Function A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc. function function the function of a hammer to drive in nails the function of a heart pacemaker to regulate the beating of a heart through electricity the function of amylase in saliva to break down starch into sugar material entity 物质实体 (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] 物质实体(MaterialEntity) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. BFO:0000040 MaterialEntity a flame material Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) MaterialEntity a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic bfo every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) material material entity the undetached arm of a human being BFO 2参考文献：“物质”旨在涵盖质量和能量（我们将在BFO的后续版本中介绍对部分能量的本体处理）。物质的一部分是任何包括基本粒子在内的适当或不适当的部分：夸克和轻子，包括电子，是迄今为止发现的最小的粒子；重子粒子在更高的粒度水平（包括质子和中子）；原子和分子的含量更高，形成由生物学家研究的细胞、器官、生物体和其他物质实体，由地质学家研究的岩石部分，由古生物学家研究的化石等等。物质实体是三维实体（在三个空间维度上扩展的实体），与它们参与的过程相反，它们是四维实体 （实体也沿着时间维度延伸）。根据FMA，物质实体可以有作为部分的非物质实体-包括下面标识为位置的实体；例如你的小肠的内部（或“腔”）是您身体的一部分。 BFO 2.0在这里体现了遵循FMA的决定。 BFO 2参考：对象，许可对象部分和对象聚合并是材料实体的细节。邀请用户提出物质实体的新子类别。 BFO 2参考：物质实体（常体）甚至可以在获得和丢失物质部分时保持其性质。常体与行体形成对比，后者在连续的时间部分或阶段展开自己[60] 一个人 一个人的无袖手臂 一个光子 一个海浪 一个物质实体是一个独立常体，它的某些部分是适当的或不适当的常体部分。 （BFO2公理标签参考：[019-002]） 一个独立常体，是空间扩展的，其性质独立于其他实体，可以通过时间来维持。 一个能量波 一场流行病 一阵烟雾 一阵龙卷风 人类的一个总和。 以一个物质实体作为常体部分的每个实体都是物质实体。 （BFO2公理标签参考：[020-002]） 森林大火 火焰 物质 物质实体 物质实体为常体部分的每个实体也是物质实体。 （BFO2公理标签参考：[021-002]） 飓风 immaterial entity 非物质实体 BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10 immaterial ImmaterialEntity anatomical structure 解剖结构 material anatomical entity 物质解剖实体 cell part 细胞部分 dopamine 0 153.079 153.17840 2-(3,4-Dihydroxyphenyl)ethylamine 2-(3,4-dihydroxyphenyl)ethylamine 3,4-Dihydroxyphenethylamine 3-Hydroxytyramine 4-(2-Aminoethyl)-1,2-benzenediol 4-(2-Aminoethyl)benzene-1,2-diol 4-(2-aminoethyl)-1,2-benzenediol 4-(2-aminoethyl)benzene-1,2-diol 4-(2-aminoethyl)catechol 4-(2-aminoethyl)pyrocatechol C8H11NO2 CAS:51-61-6 CHEBI:11695 CHEBI:11930 CHEBI:14203 CHEBI:1764 CHEBI:18243 CHEBI:23886 CHEBI:43686 Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. Deoxyepinephrine Dopamine DrugBank:DB00988 Drug_Central:947 HMDB:HMDB0000073 Hydroxytyramin InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 KEGG:C03758 KEGG:D07870 KNApSAcK:C00001408 LINCS:LSM-4630 MetaCyc:DOPAMINE NCCc1ccc(O)c(O)c1 PMID:10629745 PMID:11149432 PMID:9422813 Reaxys:1072822 VYFYYTLLBUKUHU-UHFFFAOYSA-N Wikipedia:Dopamine chebi_ontology dopamina dopamine dopaminum molecular entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. CHEBI:23367 chebi_ontology estradiol 0 272.178 272.38196 A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17. C18H24O2 CHEBI:23965 CHEBI:42364 InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1 PMID:10696569 PMID:24084694 VOXZDWNPVJITMN-WKUFJEKOSA-N Wikipedia:Estradiol [H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21 chebi_ontology estra-1,3,5(10)-triene-3,17-diol oestradiol chemical entity chemical entity 化学实体 A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. CHEBI:24431 chebi_ontology chemical entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. CHEBI:24431 chebi_ontology chemical entity 化学实体 化学实体是对化学感兴趣的物理实体，包括分子实体、其部分及化学物质。 estriol (16alpha,17beta)-estra-1,3,5(10)-triene-3,16,17-triol 0 1,3,5(10)-Estratriene-3,16-alpha,17beta-triol 16alpha,17beta-estriol 16alpha-hydroxyestradiol 288.173 288.38140 3,16alpha,17beta-trihydroxy-Delta(1,3,5)-estratriene A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer). Beilstein:2508172 C18H24O3 CAS:50-27-1 CHEBI:23969 CHEBI:27974 CHEBI:42467 CHEBI:4869 DrugBank:DB04573 Drug_Central:3187 ESTRIOL Estriel Estriol HMDB:HMDB0000153 InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1 KEGG:C05141 KEGG:D00185 LINCS:LSM-2368 LIPID_MAPS_instance:LMST02010003 MetaCyc:ESTRIOL Oestriol PDBeChem:ESL PMID:11133265 PMID:23777262 PMID:9373313 PROQIPRRNZUXQM-ZXXIGWHRSA-N Reaxys:2508172 Wikipedia:Estriol [H][C@]12CC[C@]3(C)[C@@H](O)[C@H](O)C[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21 chebi_ontology estra-1,3,5(10)-triene-3,16alpha,17beta-triol oestriol trihydroxyestrin serotonin 0 176.095 176.215 3-(2-Aminoethyl)-1H-indol-5-ol 3-(2-aminoethyl)-1H-indol-5-ol 5-HT 5-Hydroxytryptamine A primary amino compound that is the 5-hydroxy derivative of tryptamine. Beilstein:143524 C10H12N2O C1=CC(=CC=2C(=CNC12)CCN)O CAS:50-67-9 CHEBI:1420 CHEBI:26652 CHEBI:28790 CHEBI:49894 Enteramine Gmelin:1861995 HMDB:HMDB0000259 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 KEGG:C00780 KNApSAcK:C00001429 LINCS:LSM-6589 MetaCyc:SEROTONIN PDBeChem:SRO PMID:18593914 PMID:22770225 PMID:24136337 QZAYGJVTTNCVMB-UHFFFAOYSA-N Reaxys:143524 SEROTONIN Serotonin Wikipedia:Serotonin chebi_ontology serotonine thrombocytin thrombotonin organic group Any substituent group or skeleton containing carbon. CHEBI:33247 chebi_ontology catecholamine 0 151.063 151.163 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. C8H9NO2R2 CHEBI:23056 CHEBI:33567 CHEBI:3468 Catecholamine KEGG:C02012 catecholamines catecholamines chebi_ontology adrenaline (+-)-adrenaline (+-)-epinephrine 0 183.090 183.20446 2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen. Beilstein:2212160 C9H13NO3 CAS:329-65-7 CHEBI:33568 CNCC(O)c1ccc(O)c(O)c1 Drug_Central:4508 Gmelin:51559 InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 LINCS:LSM-4958 PMID:10052027 PMID:24252294 PMID:24719616 Reaxys:2212160 UCTWMZQNUQWSLP-UHFFFAOYSA-N chebi_ontology dl-adrenaline epinephrine racemic racepinefrina racepinefrine racepinefrinum amino-acid residue CHEBI:33708 When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. amino acid residue chebi_ontology protein residue Collagen Collagen 胶原蛋白 C4H6N2O3R2(C7H9N2O2R)n CAS:9064-67-9 CHEBI:3815 Collagen KEGG:C00211 chebi_ontology C4H6N2O3R2(C7H9N2O2R)n CAS:9064-67-9 CHEBI:3815 Collagen KEGG:C00211 chebi_ontology 胶原蛋白 organic amino compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. CHEBI:50047 chebi_ontology latrunculin A latrunculin A 拉春库林A (+)-latrunculin A (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one 0 421.192 421.55000 A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. C22H31NO5S CAS:76343-93-6 CHEBI:43626 CHEBI:69136 DDVBPZROPPMBLW-IZGXTMSKSA-N InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1 LAT-A LATRUNCULIN A LatA NSC 613011 PDBeChem:LAR PMID:10859320 PMID:12087066 PMID:17897856 PMID:19528469 PMID:20677927 PMID:22492972 PMID:22498812 PMID:3200109 PMID:3556584 PMID:9250716 Reaxys:4239363 [H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@H]2C[C@@H](CC[C@H](C)\C=C/C=C/CC\C(C)=C/C(=O)O2)O1 chebi_ontology (+)-latrunculin A (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one 0 421.192 421.55000 A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. C22H31NO5S CAS:76343-93-6 CHEBI:43626 CHEBI:69136 DDVBPZROPPMBLW-IZGXTMSKSA-N InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1 LAT-A LATRUNCULIN A LatA NSC 613011 PDBeChem:LAR PMID:10859320 PMID:12087066 PMID:17897856 PMID:19528469 PMID:20677927 PMID:22492972 PMID:22498812 PMID:3200109 PMID:3556584 PMID:9250716 Reaxys:4239363 [H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@H]2C[C@@H](CC[C@H](C)\C=C/C=C/CC\C(C)=C/C(=O)O2)O1 chebi_ontology (+)-拉春库林A 一种双环大环内酯类天然产物，由一种十六元的双环内酯，附在罕见的2-噻唑酮中形成。它是取自红海海绵Latrunculia magnifica和斐济群岛海绵Cacospongia mycofijiensis。微丝解聚剂抑制肌动蛋白聚合，微丝组织和微丝介导的过程。 拉春库林A cell line cell culturing cell line cell culturing 细胞系细胞培养 a maintaining cell culture process that keeps cell line cell alive and actively cultured. 维持细胞株存活和活跃培养的细胞培养过程。 YH YH a maintaining cell culture process that keeps cell line cell alive and actively cultured. cell line cell cell line cell 细胞系细胞 A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture cell line cell 一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分 Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters A 'cell line cell' is a part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures. A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture 一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分 A 'cell line cell' is a part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures. Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters cell line cell “细胞系细胞”是通过原代培养细胞的传代/选择或现有细胞系的实验性修饰而建立的细胞系的一部分。新类型的细胞系细胞的建立过程是原代培养物充分传代后以建立符合条件（典型地1-20代）的稳定且同质的群体，或者在某些自发或实验性修饰之后赋予现有细胞系新的特征。与产生细胞系细胞的原始细胞相比，细胞系细胞通常具有5个或更多个基因的突变。 一些基因突变可能会开启一些致癌基因。 细胞系细胞可处于活性培养物中，以静止状态储存以供将来使用（例如在液氮中冷冻），或者在实验程序使用。 细胞系细胞 suspension cell line culturing suspension cell line culturing 悬浮细胞培养 悬浮细胞系培养是其中细胞不需要生长和分化表面的细胞系培养方法。 该方法适用于适合悬浮培养的细胞或非贴壁细胞（如造血细胞） suspension cell line culturing is a cell line culturing method where cells do not require a surface for growth and differentiation. This method is appropriate for cells that are adapted to suspension culture or cells that are non-adhesive (e.g. hematopoietic cells) suspension cell line culturing is a cell line culturing method where cells do not require a surface for growth and differentiation. This method is appropriate for cells that are adapted to suspension culture or cells that are non-adhesive (e.g. hematopoietic cells) adherent cell line culturing adherent cell line culturing 贴壁细胞系培养 adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation. adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation. 贴壁细胞系培养是一种细胞系培养方法，其中细胞需要一个表面进行生长和分化。 cell line cell modification a material processing that modifies an existing cell line cell to generate another cell line cell. Yongqun He cell line repository role cell line repository role 细胞库角色 SS, YH a role that inheres in a cell line repository organization. 一个细胞系资源组织中所起的作用 SS, YH a role that inheres in a cell line repository organization. cell line repository cell line repository 细胞库 一个作为细胞系存储库的组织。 SS, YH SS, YH an organization that serves as a repository of cell lines. an organization that serves as a repository of cell lines. adherent on coated surface cell line culturing adherent on coated surface cell line culturing is an adherent cell line culturing method that the surface is coated with extracellular matrix component to increase adhesion properties and provide other signals needed for growth and differentiation. ATCC cell line cell ATCC cell line SS, YH, UV, SS a cell line cell that is in the ATCC cell line repository HyperCLDB cell line cell SS, YH, UV, SS a cell line cell that is in the HyperCLDB cell line repository HyperCLDB cell line immortal human T cell line cell 永生的人T细胞系细胞 an immortal human lymphocyte cell line cell that is derived from T cell. 一种源自T细胞的永生人淋巴细胞系细胞。 YH YH an immortal human lymphocyte cell line cell that is derived from T cell. adherent on feeder cells cell line culturing adherent on feeder cells cell line culturing 在饲养细胞上贴壁培养细胞系 adherent-patchy cell line culturing adherent-patchy cell line culturing 贴壁斑片状细胞培养 loosely adherent cell line culturing loosely adherent cell line culturing 松散贴壁细胞培养 mouse, Swiss albino mortal cell line cell mortal cell line cell 非永生细胞系细胞 finite cell line cell Yongqun He, Matthew Brush, Sirarat Sarntivijai A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence. A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence. Yongqun He, Matthew Brush, Sirarat Sarntivijai finite cell line cell 有限细胞系细胞 immortal cell line cell immortal cell line cell 永生细胞系细胞 immortal cell line cell permanent cell line cell A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line. Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak continuous cell line cell 连续细胞系细胞 A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line. 预期能够进行无限次分裂的细胞系细胞，作为永生细胞系一部分，能够支持体外无限增殖。 永久细胞系细胞 Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak continuous cell line cell immortal cell line cell permanent cell line cell 永生细胞系细胞 immortal human cell line cell immortal human cell line cell 永生的人细胞系细胞 a immortal cell line that is dervied from human tissue. YH YH 一种源自人体组织的永生细胞系。 a immortal cell line that is dervied from human tissue. immortal human cell line 永生的人细胞系 immortal cat cell line cell An immortal skin-derived cell line cell that derives from cat. Yongqun He immortal frog cell line cell 永生的蛙细胞系细胞 An immortal skin-derived cell line cell that derives from frog. Yongqun He An immortal skin-derived cell line cell that derives from frog. Yongqun He 源自青蛙的永生皮肤衍生的细胞系细胞。 immortal hybrid cell line cell an immortal cell line cell that is generated by fusing two different types of cells. One of the parent cells is typically a cancer cell. Yongqun He immortal zebra fish cell line cell An immortal cell line cell that derives from zebra fish. Yongqun He mouse immortal cell line cell mouse immortal cell line suspension cell line cell suspension cell line a cell line that requires suspension cell cuturing. adherent cell line cell adherent cell line a cell line that is cultured through adherence cell culturing. adherent cell culture growth mode adherent cell culture growth mode 贴壁细胞培养生长模式 一种细胞培养生长模式：细胞需要粘附在细胞培养板上生长 YH YH a cell culture growth mode that indicates a cell needs to adhere to a cell culture plate to grow. a cell culture growth mode that indicates a cell needs to adhere to a cell culture plate to grow. suspension cell culture growth mode suspension cell culture growth mode 悬浮细胞培养生长模式 YH a cell culture growth mode that indicates a cell can grow when the cell is suspended in cell culture medium. a cell culture growth mode that indicates a cell can grow when the cell is suspended in cell culture medium. 一种细胞培养生长模式：当细胞悬浮在细胞培养基中时，细胞可以生长 YH cell culture growth mode cell culture growth mode 细胞培养生长模式 YH a disposition that represents a mode of cell culture growth, i.e., the cell will grow at a specific cell culture mode. For example, an adherent cell culture growh mode means that the cell will grow when the cell is adhere to a cell culture plate. YH a disposition that represents a mode of cell culture growth, i.e., the cell will grow at a specific cell culture mode. For example, an adherent cell culture growh mode means that the cell will grow when the cell is adhere to a cell culture plate. 一种代表细胞培养生长模式的配置，即细胞将以特定细胞培养模式生长。 例如，贴壁细胞培养生长模式意味着当细胞粘附于细胞培养板时细胞将生长。 cell line 细胞系 A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene". Note that common usage in the literature is often of the form "a human colorectal cancer cell line", as seen above. But such references to studies in "a line" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'. In the spring of 2013, a working group comprised of domain experts and representatives from CLO, OBI, CL, and ReO worked to establish a consensus model and definitions of cultured cells across these efforts. This included a careful characterization of how the term 'cell line' should be defined and applied. Notes about this work and its outcomes can be found on the CLO wiki here: http://code.google.com/p/clo-ontology/wiki/Cell_Lines The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, ‘lines’ are capable of being characterized and stably propagated over a period of time. A new *type* of cell line can be established not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.). The definition provided here establishes the 'scale' of cell populations that qualify as cell lines - specifically those with a shared propagation history in culture. In this way, the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.  As defined here, 'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quiescent state for future use. 当培养物经过有意的实验过程以建立更均匀和稳定的细胞群时（参见“建立细胞系”），使用术语“系”。这将需要一个或多次传代，但可能涉及额外的选择过程。通过这样的传代和/或选择过程，产生的'细胞系'达到一定水平的遗传稳定性和组成均一性，这在原代培养物中通常是不存在的。由于它们的相对同质性，“细胞系”能够在一段时间内被表征和稳定地增殖。一种新*型*细胞系不仅可以通过原代培养物的传代/选择建立，而且可以通过对现有系列的实验性修饰（例如永生化，稳定的遗传修饰，用于抗性子集的药物选择等）来建立。 这里提供的定义确立了符合细胞系特征的细胞群的“范围” - 特别是那些在培养中具有共同繁殖历史的细胞群。通过这种方式，“细胞系”类划分代表研究人员在科学实践中实际使用的细胞群 - 例如作为培养、实验和分享的投入。定义是这样的，细胞系将显示重要的属性。例如，它们将具有相对均匀的细胞类型组成，因为它们的连续共增殖而经历了类似的选择压力。此外，这些细胞群还可以通过传代数来表征，这也是由于它们共同的传代史。如此处所定义的，“细胞系”可以指活性培养物中，实验性应用的或以静止状态存储以备将来使用的细胞群。 He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene". Note that common usage in the literature is often of the form "a human colorectal cancer cell line", as seen above. But such references to studies in "a line" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'. A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). In the spring of 2013, a working group comprised of domain experts and representatives from CLO, OBI, CL, and ReO worked to establish a consensus model and definitions of cultured cells across these efforts. This included a careful characterization of how the term 'cell line' should be defined and applied. Notes about this work and its outcomes can be found on the CLO wiki here: http://code.google.com/p/clo-ontology/wiki/Cell_Lines MB, SS, JZ, MAH, BP, CS, YH MB, SS, JZ, MAH, BP, CS, YH 在2013年春季，由CLO，OBI，CL和ReO的领域专家和代表组成的工作组经过这些努力中建立了共识模型和培养细胞的定义。 这包括仔细描述术语“细胞系”应该如何定义和应用。 关于这项工作及其结果的说明可以在CLO wiki上找到： http://code.google.com/p/clo-ontology/wiki/Cell_Lines The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, ‘lines’ are capable of being characterized and stably propagated over a period of time. A new *type* of cell line can be established not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.). The definition provided here establishes the 'scale' of cell populations that qualify as cell lines - specifically those with a shared propagation history in culture. In this way, the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.  As defined here, 'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quiescent state for future use. 一个培养细胞群体，其代表具有共同增殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。 培养的细胞群体代表具有共同繁殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。 He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "为了评估APC的转录效应，我们研究了含有锌诱导型APC基因的人结直肠癌细胞系（HT29-APC）和含有类似诱导型lacZ基因的对照细胞系（HT29-β-Gal）". 请注意，文献中的常见用法通常是“人类结直肠癌细胞系”的形式",如上所见。 但是对"一个细胞系"研究的这种引用，指的是输入培养或实验的离散细胞群体，而不是整个细胞系。 我们将这些离散的群体称为'细胞系'。 cell line 细胞系 mixed adherent and suspension cell line culturing mixed adherent and suspension cell line culturing 混合贴壁悬浮细胞培养 mixed suspension clusters in suspension cell line culturing clusters in suspension cell line culturing 在悬浮细胞系培养中的成簇细胞 cell line co-expression Oliver Note: this term needs precise definition. will consult term users later. Ba/F3 cell line co-expression Ba/F3 Stably co-expresses EpoR and JAK2V617F EpoR and JAK2V617F constructs Ba/F3 cell line EpoR and JAK2V617F co-expression CHO cell line co-expression CHO cell line co-expression of lactamase CHO Established (in your ontology) Stably transfected with Cre-beta lactamase: Cre Bla CHO cell line suspension with feeder cells cell line culturing suspension-multicell aggregates cell line culturing immortal mouse cell line cell immortal mouse cell line cell 永生的小鼠细胞系细胞 a immortal cell line that is dervied from mouse tissue. Yue Liu, Yongqun He Yue Liu, Yongqun He a immortal cell line that is dervied from mouse tissue. immortal mouse cell line 从老鼠组织中得到的一种永生细胞系。 永生的小鼠细胞系 immortal mouse macrophage cell line a immortal cell line that is dervied from mouse macrophage. YH immortal stem cell line cell ZX, YH a cell line that is derived from stem cell immortal mouse liver cell line a immortal cell line that is dervied from mouse liver. YH immortal Gorilla gorilla cell line cell a immortal cell line that is dervied from a Gorilla gorilla tissue. YH immortal Gorilla gorilla cell line immortal somatic stem cell line cell ZX, YH a immortal stem cell line that is derived from somatic stem cell immortal epithelial fate stem cell line cell ZX, YH a immortal somatic stem cell line that is derived from epithelial fate stem cell immortal basal cell line cell ZX, YH a immortal epithelial fate stem cell line that is derived from basal cell immortal multi fate stem cell line cell ZX, YH a immortal somatic stem cell line that is derived from multi fate stem cell immortal neuronal stem cell line cell ZX, YH a immortal multi fate stem cell line that is derived from neuronal stem cell immortal neuroblast cell line cell ZX, YH a immortal neuronal stem cell line that is derived from neuroblast immortal mesenchymal cell line cell ZX, YH a immortal multi fate stem cell line that is derived from mesenchymal cell immortal non-terminally differentiated cell line cell immortal non-terminally differentiated cell line cell 永生的非终末分化细胞系细胞 ZX, YH a cell line that is derived from non-terminally differentiated cell immortal non-terminally differentiated cell line ZX, YH a cell line that is derived from non-terminally differentiated cell immortal non-terminally differentiated cell line 永生的非终末分化细胞系 源自非终末分化细胞的细胞系 immortal osteoblast cell line cell ZX, YH a immortal non-terminally differentiated cell line that is derived from osteoblast immortal osteoblast cell line immortal muscle precursor cell line cell immortal muscle precursor cell line cell 永生的肌前体细胞系细胞 ZX, YH a immortal non-terminally differentiated cell line that is derived from muscle precursor cell immortal muscle precursor cell line ZX, YH a immortal non-terminally differentiated cell line that is derived from muscle precursor cell immortal muscle precursor cell line 永生的肌前体细胞系 源自肌前体细胞的永生非终末分化细胞系 immortal myoblast cell line cell immortal myoblast cell line cell 永生的成肌细胞系细胞 ZX, YH a immortal muscle precursor cell line that is derived from myoblast immortal myoblast cell line ZX, YH a immortal muscle precursor cell line that is derived from myoblast immortal myoblast cell line 永生的成肌细胞系 源自成肌细胞的永生肌肉前体细胞系 immortal fusion competent myoblast cell line cell ZX, YH a immortal myoblast cell line that is derived from fusion competent myoblast immortal fusion competent myoblast cell line immortal secretory cell line cell immortal secretory cell line cell 永生的分泌细胞系细胞 ZX, YH a cell line that is derived from secretory cell immortal secretory cell line ZX, YH a cell line that is derived from secretory cell immortal secretory cell line 永生的分泌细胞系 源自分泌细胞的细胞系 immortal glandular epithelial cell line cell ZX, YH a immortal secretory cell line that is derived from glandular epithelial cell immortal anterior pituitary gland chromophil cell line cell ZX, YH a immortal glandular epithelial cell line cell that is derived from chromophil cell of anterior pituitary gland immortal thyrotroph cell line cell ZX, YH a immortal chromophil cell line cell of anterior pituitary gland that is derived from thyrotroph immortal pars distalis of adenohypophysis acidophil cell line cell ZX, YH a immortal chromophil cell line of anterior pituitary gland that is derived from acidophil cell of pars distalis of adenohypophysis immortal neck cell line cell ZX, YH a immortal glandular epithelial cell line that is derived from neck cell immortal glandular cell line of stomach cell ZX, YH a immortal glandular epithelial cell line that is derived from glandular cell of stomach immortal parietal cell line cell ZX, YH a immortal glandular cell line of stomach that is derived from parietal cell immortal exocrine cell line cell ZX, YH a immortal secretory cell line that is derived from exocrine cell immortal exocrine cell line immortal endocrine cell line cell immortal endocrine cell line cell 永生的内分泌细胞系细胞 ZX, YH a immortal secretory cell line that is derived from endocrine cell immortal endocrine cell line ZX, YH a immortal secretory cell line that is derived from endocrine cell immortal endocrine cell line 永生的内分泌细胞系 源自内分泌细胞的永生分泌细胞系 immortal mast cell line cell immortal mast cell line cell 永生的肥大细胞系细胞 ZX, YH a immortal endocrine cell line that is derived from mast cell immortal mast cell line ZX, YH a immortal endocrine cell line that is derived from mast cell immortal mast cell line 永生的肥大细胞系 由肥大细胞衍生的永生内分泌细胞系 immortal neuroendocrine cell line cell ZX, YH a immortal endocrine cell line cell that is derived from neuroendocrine cell immortal Leydig cell line cell ZX, YH a immortal endocrine cell line that is derived from Leydig cell immortal Leydig cell line immortal Sertoli cell line cell ZX, YH a immortal secretory cell line cell that is derived from Sertoli cell immortal plasma cell line cell immortal plasma cell line cell 永生的浆细胞系细胞 ZX, YH a immortal secretory cell line that is derived from plasma cell immortal plasma cell line ZX, YH a immortal secretory cell line that is derived from plasma cell immortal plasma cell line 永生的浆细胞系 源自浆细胞的永生分泌细胞系 immortal contractile cell line cell immortal contractile cell line cell 永生化的收缩细胞系细胞 ZX, YH an immortal cell line cell that is derived from contractile cell ZX, YH an immortal cell line cell that is derived from contractile cell 源自收缩细胞的永生细胞系细胞 immortal myofibroblast cell line cell ZX, YH a immortal contractile cell line cell that is derived from myofibroblast cell immortal muscle cell line cell immortal muscle cell line cell 永生的肌肉细胞系细胞 ZX, YH a immortal contractile cell line cell that is derived from muscle cell ZX, YH a immortal contractile cell line cell that is derived from muscle cell 源自肌肉细胞的永生收缩细胞系细胞 immortal skeletal muscle cell line cell ZX, YH a immortal muscle cell line cell that is derived from skeletal muscle cell immortal smooth muscle cell line cell ZX, YH a immortal muscle cell line cell that is derived from smooth muscle cell immortal electrically active cell line cell immortal electrically active cell line cell 永生的电活性细胞系细胞 ZX, YH an immortal cell line cell that is derived from electrically active cell ZX, YH an immortal cell line cell that is derived from electrically active cell 源自电活性细胞的永生细胞系细胞 immortal electrically responsive cell line cell immortal electrically responsive cell line cell 永生的电反应细胞系细胞 ZX, YH a immortal electrically active cell line cell that is derived from electrically responsive cell ZX, YH a immortal electrically active cell line cell that is derived from electrically responsive cell 源自电反应细胞的永生电活性细胞系细胞 immortal neuron cell line cell immortal neuron cell line cell 永生的神经元细胞系细胞 ZX, YH a immortal electrically responsive cell line cell that is derived from neuron ZX, YH a immortal electrically responsive cell line cell that is derived from neuron 源自神经元的永生电反应细胞系细胞 immortal bipolar neuron cell line cell immortal bipolar neuron cell line cell 永生的双极神经元细胞系细胞 ZX, YH a immortal neuron cell line cell that is derived from bipolar neuron ZX, YH a immortal neuron cell line cell that is derived from bipolar neuron 源自双极神经元的永生神经元细胞系细胞 immortal ON-bipolar cell line cell ZX, YH a immortal bipolar neuron cell line cell that is derived from ON-bipolar cell immortal peripheral neuron cell line cell immortal peripheral neuron cell line cell 永生的外周神经元细胞系细胞 ZX, YH a immortal neuron cell line cell that is derived from peripheral neuron ZX, YH a immortal neuron cell line cell that is derived from peripheral neuron 源自外周神经元的永生神经元细胞系细胞 immortal stellate cell line cell ZX, YH a immortal neuron cell line cell that is derived from stellate cell immortal barrier cell line cell ZX, YH an immortal cell line cell that is derived from barrier cell immortal lining cell line cell ZX, YH an immortal barrier cell line cell that is derived from lining cell immortal mesothelial cell line cell ZX, YH a immortal lining cell line cell that is derived from mesothelial cell immortal seminiferous tubule epithelial cell line cell ZX, YH a immortal mesothelial cell line cell that is derived from seminiferous tubule epithelial cell immortal spermatocyte cell line cell ZX, YH a immortal seminiferous tubule epithelial cell line cell that is derived from spermatocyte immortal endothelial cell line cell ZX, YH a immortal lining cell line cell that is derived from endothelial cell immortal myelinating Schwann cell line cell ZX, YH a immortal barrier cell line cell that is derived from myelinating Schwann cell immortal motile cell line cell immortal motile cell line cell 永生的游动细胞系细胞 ZX, YH a cell line that is derived from motile cell immortal motile cell line ZX, YH a cell line that is derived from motile cell immortal motile cell line 永生的游动细胞系 源自运动细胞的细胞系 immortal phagocyte cell line cell immortal phagocyte cell line cell 永生的吞噬细胞细胞系细胞 ZX, YH a immortal motile cell line that is derived from phagocyte ZX, YH a immortal motile cell line that is derived from phagocyte 源自吞噬细胞的永生游动细胞系， immortal mononuclear phagocyte cell line cell ZX, YH a immortal phagocyte cell line that is derived from mononuclear phagocyte immortal macrophage cell line cell immortal macrophage cell line cell 永生的巨噬细胞系细胞 ZX, YH a immortal phagocyte cell line that is derived from macrophage ZX, YH a immortal phagocyte cell line that is derived from macrophage 源自巨噬细胞的永生吞噬细胞系 immortal tissue-resident macrophage cell line cell ZX, YH a immortal macrophage cell line that is derived from tissue-resident macrophage immortal microglial cell line cell ZX, YH a immortal tissue-resident macrophage cell line that is derived from microglial cell immortal peritoneal macrophage cell line cell ZX, YH a immortal tissue-resident macrophage cell line that is derived from peritoneal macrophage immortal polygonal cell line cell ZX, YH a immortal phagocyte cell line that is derived from polygonal cell immortal polygonal cell line immortal amoeboid cell line cell ZX, YH a immortal motile cell line that is derived from amoeboid cell immortal amoeboid cell line immortal leukocyte cell line cell immortal leukocyte cell line cell 永生的白细胞系细胞 ZX, YH a immortal motile cell line that is derived from leukocyte immortal leukocyte cell line ZX, YH a immortal motile cell line that is derived from leukocyte immortal leukocyte cell line 永生的白细胞系 源自白细胞的永生游动细胞系 immortal dendritic cell line cell ZX, YH a immortal leukocyte cell line that is derived from dendritic cell immortal dendritic cell line immortal Langerhans cell line cell ZX, YH a immortal dendritic cell line that is derived from Langerhans cell immortal Langerhans cell line immortal myeloid leukocyte cell line cell immortal myeloid leukocyte cell line cell 永生的髓样白血球细胞系细胞 ZX, YH a immortal leukocyte cell line that is derived from myeloid leukocyte immortal myeloid leukocyte cell line ZX, YH a immortal leukocyte cell line that is derived from myeloid leukocyte immortal myeloid leukocyte cell line 永生的髓样白血球细胞系 源自髓系白细胞的永生白细胞系 immortal monocyte cell line cell immortal monocyte cell line cell 永生的单核细胞系细胞 ZX, YH a immortal myeloid leukocyte cell line that is derived from monocyte immortal monocyte cell line ZX, YH a immortal myeloid leukocyte cell line that is derived from monocyte immortal monocyte cell line 永生的单核细胞系 源自单核细胞的永生髓系白细胞系 immortal nongranular leukocyte cell line cell immortal nongranular leukocyte cell line cell 永生的无颗粒白细胞细胞系细胞 ZX, YH a immortal leukocyte cell line that is derived from nongranular leukocyte immortal nongranular leukocyte cell line ZX, YH a immortal leukocyte cell line that is derived from nongranular leukocyte immortal nongranular leukocyte cell line 永生的无颗粒白细胞细胞系 源自无粒白细胞的永生白细胞细胞系 immortal lymphocyte cell line cell immortal lymphocyte cell line cell 永生的淋巴细胞系细胞 ZX, YH a immortal nongranular leukocyte cell line that is derived from lymphocyte immortal lymphocyte cell line ZX, YH a immortal nongranular leukocyte cell line that is derived from lymphocyte immortal lymphocyte cell line 永生的淋巴细胞系 源自淋巴细胞的永生无颗粒白细胞细胞系 immortal T cell line cell immortal T cell line cell 永生的T细胞系细胞 ZX, YH a immortal lymphocyte cell line that is derived from T cell immortal T cell line ZX, YH a immortal lymphocyte cell line that is derived from T cell immortal T cell line 永生的T细胞系 源自T细胞的永生淋巴细胞系 immortal alpha-beta T cell line cell ZX, YH a immortal T cell line that is derived from alpha-beta T cell immortal alpha-beta T cell line immortal immature alpha-beta T cell line cell ZX, YH a immortal alpha-beta T cell line that is derived from immature alpha-beta T cell immortal immature alpha-beta T cell line immortal double-positive, alpha-beta thymocyte cell line cell ZX, YH a immortal immature alpha-beta T cell line that is derived from double-positive, alpha-beta thymocyte immortal double-positive, alpha-beta thymocyte cell line immortal mature alpha-beta T cell line cell ZX, YH a immortal alpha-beta T cell line that is derived from mature alpha-beta T cell immortal mature alpha-beta T cell line immortal CD4-positive, CD25-positive, alpha-beta regulatory T cell line cell ZX, YH a immortal mature alpha-beta T cell line that is derived from CD4-positive, CD25-positive, alpha-beta regulatory T cell immortal CD4-positive, CD25-positive, alpha-beta regulatory T cell line immortal induced T-regulatory cell line cell ZX, YH a immortal CD4-positive, CD25-positive, alpha-beta regulatory T cell line that is derived from induced T-regulatory cell immortal induced T-regulatory cell line immortal mature T cell line cell ZX, YH a immortal T cell line that is derived from mature T cell immortal mature T cell line immortal helper T cell line cell ZX, YH a immortal mature T cell line that is derived from helper T cell immortal helper T cell line immortal immature T cell line cell ZX, YH a immortal T cell line that is derived from immature T cell immortal immature T cell line immortal B cell line cell immortal B cell line cell 永生的B细胞系细胞 ZX, YH a immortal lymphocyte cell line that is derived from B cell immortal B cell line ZX, YH a immortal lymphocyte cell line that is derived from B cell immortal B cell line immortal B-cell line cell 永生的B-细胞系细胞 永生的B细胞系 源自B细胞的永生淋巴细胞系 immortal precursor B cell line cell ZX, YH a immortal B cell line that is derived from precursor B cell immortal precursor B cell line immortal natural killer cell line cell ZX, YH a immortal lymphocyte cell line that is derived from natural killer cell immortal natural killer cell line immortal single nucleate cell line cell ZX, YH a cell line that is derived from single nucleate cell immortal single nucleate cell line immortal multinucleate cell line cell ZX, YH a cell line that is derived from multinucleate cell immortal multinucleate cell line immortal eukaryotic cell line cell immortal eukaryotic cell line cell 永生的真核细胞系细胞 ZX, YH a immortal cell line cell that is derived from eukaryotic cell ZX, YH a immortal cell line cell that is derived from eukaryotic cell 源自真核细胞的永生细胞系细胞 immortal vegetative cell line (sensu Mycetozoa) cell ZX, YH a immortal eukaryotic cell line that is derived from vegetative cell (sensu Mycetozoa) immortal vegetative cell line (sensu Mycetozoa) immortal aggregate cell line cell ZX, YH a immortal vegetative cell line (sensu Mycetozoa) that is derived from aggregate cell immortal aggregate cell line immortal anterior like cell line cell ZX, YH a immortal vegetative cell line (sensu Mycetozoa) that is derived from anterior like cell immortal anterior like cell line immortal animal cell line cell immortal animal cell line cell 永生的动物细胞系细胞 ZX, YH a immortal eukaryotic cell line that is derived from animal cell immortal animal cell line ZX, YH a immortal eukaryotic cell line that is derived from animal cell immortal animal cell line 永生的动物细胞系 源自动物细胞的永生真核细胞系 immortal epithelial cell line cell immortal epithelial cell line cell 永生的上皮细胞系细胞 ZX, YH a immortal animal cell line that is derived from epithelial cell ZX, YH a immortal animal cell line that is derived from epithelial cell 源自上皮细胞的永生动物细胞系 immortal duct epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from duct epithelial cell immortal columnar/cuboidal epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from columnar/cuboidal epithelial cell immortal neurecto-epithelial cell line cell ZX, YH a immortal columnar/cuboidal epithelial cell line that is derived from neurecto-epithelial cell immortal neurecto-epithelial cell line immortal melanocyte cell line cell ZX, YH a immortal neurecto-epithelial cell line that is derived from melanocyte immortal pigmented epithelial cell line cell ZX, YH a immortal neurecto-epithelial cell line that is derived from pigmented epithelial cell immortal pigmented epithelial cell line immortal squamous epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from squamous epithelial cell immortal stratified squamous epithelial cell line cell ZX, YH a immortal squamous epithelial cell line that is derived from stratified squamous epithelial cell immortal keratinizing barrier epithelial cell line cell ZX, YH a immortal stratified squamous epithelial cell line that is derived from keratinizing barrier epithelial cell immortal keratinocyte cell line cell ZX, YH a immortal keratinizing barrier epithelial cell line that is derived from keratinocyte immortal epidermal cell line cell ZX, YH a immortal squamous epithelial cell line that is derived from epidermal cell immortal stratified epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from stratified epithelial cell immortal epithelial cell line of lung cell ZX, YH a immortal epithelial cell line that is derived from epithelial cell of lung immortal epithelial cell line of pancreas cell ZX, YH a immortal epithelial cell line that is derived from epithelial cell of pancreas immortal ecto-epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from ecto-epithelial cell immortal meso-epithelial cell line cell ZX, YH a immortal epithelial cell line that is derived from meso-epithelial cell immortal meso-epithelial cell line immortal extraembryonic cell line cell ZX, YH a immortal animal cell line that is derived from extraembryonic cell immortal trophoblast cell line cell ZX, YH a immortal extraembryonic cell line that is derived from trophoblast cell immortal trophoblast cell line immortal hematopoietic cell line cell immortal hematopoietic cell line cell 永生的造血细胞系细胞 ZX, YH a immortal animal cell line that is derived from hematopoietic cell immortal hematopoietic cell line ZX, YH a immortal animal cell line that is derived from hematopoietic cell immortal hematopoietic cell line 永生的造血细胞系 源自造血细胞的永生动物细胞系 immortal megakaryocyte-erythroid progenitor cell line cell immortal megakaryocyte-erythroid progenitor cell line cell 永生的巨细胞红细胞祖细胞系细胞 ZX, YH a immortal hematopoietic cell line that is derived from megakaryocyte-erythroid progenitor cell immortal megakaryocyte-erythroid progenitor cell line ZX, YH a immortal hematopoietic cell line that is derived from megakaryocyte-erythroid progenitor cell immortal megakaryocyte-erythroid progenitor cell line 永生的巨细胞红细胞祖细胞系 源自巨核细胞-红细胞祖细胞的永生造血细胞系 immortal blood cell line cell immortal blood cell line cell 永生的血细胞系细胞 ZX, YH a immortal hematopoietic cell line that is derived from blood cell immortal blood cell line ZX, YH a immortal hematopoietic cell line that is derived from blood cell immortal blood cell line 永生的血细胞系 源自血细胞的永生造血细胞系 immortal myeloid cell line cell immortal myeloid cell line cell 永生的骨髓细胞系细胞 ZX, YH a immortal hematopoietic cell line that is derived from myeloid cell immortal myeloid cell line ZX, YH a immortal hematopoietic cell line that is derived from myeloid cell immortal myeloid cell line 永生的骨髓细胞系 源自骨髓细胞的永生造血细胞系 immortal erythroblast cell line cell ZX, YH a immortal myeloid cell line that is derived from erythroblast immortal erythroblast cell line immortal hematopoietic lineage restricted progenitor cell line cell immortal hematopoietic lineage restricted progenitor cell line cell 永生的造血系限制性祖细胞系细胞 ZX, YH a immortal hematopoietic cell line that is derived from hematopoietic lineage restricted progenitor cell immortal hematopoietic lineage restricted progenitor cell line ZX, YH a immortal hematopoietic cell line that is derived from hematopoietic lineage restricted progenitor cell immortal hematopoietic lineage restricted progenitor cell line 永生的造血系限制性祖细胞系 源自造血谱系限制性祖细胞的永生造血细胞系 immortal pro-B cell line cell ZX, YH a immortal hematopoietic lineage restricted progenitor cell line that is derived from pro-B cell immortal pro-B cell line immortal myeloblast cell line cell immortal myeloblast cell line cell 永生的成髓细胞系细胞 ZX, YH a immortal hematopoietic lineage restricted progenitor cell line that is derived from myeloblast immortal myeloblast cell line ZX, YH a immortal hematopoietic lineage restricted progenitor cell line that is derived from myeloblast immortal myeloblast cell line 永生的成髓细胞系 源自成髓细胞的永生造血谱系限制性祖细胞系 immortal basophilic myeloblast cell line cell ZX, YH a immortal myeloblast cell line that is derived from basophilic myeloblast immortal basophilic myeloblast cell line immortal neural cell line cell immortal neural cell line cell 永生的神经细胞系细胞 ZX, YH a immortal animal cell line that is derived from neural cell immortal neural cell line ZX, YH a immortal animal cell line that is derived from neural cell immortal neural cell line 永生的神经细胞系 源自神经细胞的永生动物细胞系 immortal glial cell line cell ZX, YH a immortal neural cell line that is derived from glial cell immortal glial cell line immortal glial cell line (sensu Vertebrata) cell ZX, YH a immortal glial cell line that is derived from glial cell (sensu Vertebrata) immortal glial cell line (sensu Vertebrata) immortal astrocyte cell line cell ZX, YH a immortal glial cell line (sensu Vertebrata) that is derived from astrocyte immortal astrocyte cell line immortal connective tissue cell line cell immortal connective tissue cell line cell 永生的结缔组织细胞系细胞 ZX, YH a immortal animal cell line that is derived from connective tissue cell ZX, YH a immortal animal cell line that is derived from connective tissue cell 源自结缔组织细胞的永生动物细胞系 immortal fibroblast cell line cell immortal fibroblast cell line cell 永生的成纤维细胞系细胞 ZX, YH a immortal connective tissue cell line that is derived from fibroblast immortal fibroblast cell line ZX, YH a immortal connective tissue cell line that is derived from fibroblast immortal fibroblast cell line 永生的成纤维细胞系 源自成纤维细胞的永生结缔组织细胞系 immortal stromal cell line cell ZX, YH a immortal connective tissue cell line that is derived from stromal cell immortal stromal cell line immortal stuff accumulating cell line cell immortal stuff accumulating cell line cell 永生的积聚细胞系细胞 ZX, YH a cell line that is derived from stuff accumulating cell ZX, YH a cell line that is derived from stuff accumulating cell 源自积聚细胞的细胞系。 immortal parenchymal cell line cell ZX, YH a cell line that is derived from parenchymal cell immortal parenchymal cell line immortal nucleate cell line cell immortal nucleate cell line cell 永生的核细胞系细胞 ZX, YH a cell line that is derived from nucleate cell immortal nucleate cell line ZX, YH a cell line that is derived from nucleate cell immortal nucleate cell line 永生的核细胞系 源自有核细胞的细胞系 immortal somatic cell line cell immortal somatic cell line cell 永生的体细胞系细胞 ZX, YH a cell line that is derived from somatic cell ZX, YH a cell line that is derived from somatic cell 源自体细胞的细胞系 HeLa衍生细胞系细胞 HeLa derived cell line cell HeLa derived cell line cell 源自HeLa细胞的永生上皮细胞系细胞 a immortal epithelial cell line cell that is derived from HeLa cell Yongqun He Yongqun He a immortal epithelial cell line cell that is derived from HeLa cell hybridoma cell line cell hybridoma cell line cell 杂交瘤细胞系细胞 an immortal cell line cell that is established by fusing a specific antibody-producing B cell with a myeloma (B cell cancer) cell that is selected for its ability to produce a monoclonal antibody. WEB: http://en.wikipedia.org/wiki/Hybridoma_technology The production of monoclonal antibodies using the hybridoma technology was invented by Cesar Milstein and Georges J. F. Köhler in 1975. They shared the Nobel Prize of 1984 for Medicine and Physiology with Niels Kaj Jerne, who made other contributions to immunology. The production of monoclonal antibodies using the hybridoma technology was invented by Cesar Milstein and Georges J. F. Köhler in 1975. They shared the Nobel Prize of 1984 for Medicine and Physiology with Niels Kaj Jerne, who made other contributions to immunology. WEB: http://en.wikipedia.org/wiki/Hybridoma_technology Yongqun He Yongqun He 利用杂交瘤技术生产单克隆抗体是由Cesar Milstein和Georges J. F.Köhler于1975年发明的。他们与为免疫学做出贡献的Niels Kaj Jerne共同获得了1984年的诺贝尔医学和生理学奖。 an immortal cell line cell that is established by fusing a specific antibody-producing B cell with a myeloma (B cell cancer) cell that is selected for its ability to produce a monoclonal antibody. 通过将产生特异性抗体的B细胞与针对其产生单克隆抗体的能力而选择的骨髓瘤（B细胞癌）进行细胞融合而建立的永生细胞系细胞。 cell passageble capability Yongqun He a function of a cell that can be passaged in culture medium without death or genetic change. cell line lineage This term will be a subclass of BFO 2 'history'. The BFO 2 'history' term will be imported to CLO after the BFO 2 is finalized. Yongqun He cell line lineage is a history of the development of a cell line. The cell line lineage may include the original cell type from a tissue and organism that derives the cell line cell. It may also include the cell line passage and cell culturing information. Coriell cell line cell a cell line cell that is in the Coriell cell line repositories. SS, YH, UV, SS RIKEN Cell Bank cell SS, YH, UV, SS a cell line cell that is in the RIKEN Cell bank cloned cell line MHB 2013-07-16: This should be made into a defined class, using an axiom referencing a clonal cell expansion process, or a clonal cell line creation process. REO: REO_0000397 YH, SS, MHB A cell line comprised of cells which can all be traced back to a single ancestor cell, and which therefore can be treated as identical. This can be used to study just the progeny of single cells. clonal cell line immortal peripheral vein-derived B cell line cell immortal peripheral vein-derived B cell line cell 永生的外周静脉衍生B细胞系细胞 An immortal B cell line cell that derives from peripheral vein. Yue Liu, Yongqun He An immortal B cell line cell that derives from peripheral vein. Yue Liu, Yongqun He 源自外周静脉的永生B细胞系细胞 immortal organism part-derived cell line cell immortal organism part-derived cell line cell 永生的生物部分衍生细胞系细胞 An immortal cell line cell that derives from organism part. Yue Liu, Yongqun He An immortal cell line cell that derives from organism part. Yue Liu, Yongqun He 源自生物体部分的永生细胞系细胞。 immortal arm-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from arm. Yue Liu, Yongqun He immortal organism part-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from organism part. Yue Liu, Yongqun He immortal tunica albuginea of testis-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from tunica albuginea of testis. Yue Liu, Yongqun He immortal amniotic fluid-derived cell line cell An immortal cell line cell that derives from amniotic fluid. Yue Liu, Yongqun He immortal peripheral vein-derived T cell line cell immortal peripheral vein-derived T cell line cell 永生的外周静脉衍生T细胞系细胞 An immortal T cell line cell that derives from peripheral vein. Yue Liu, Yongqun He An immortal T cell line cell that derives from peripheral vein. Yue Liu, Yongqun He 源自外周静脉的永生T细胞系细胞。 immortal animal ovary-derived fibroblast cell line cell immortal animal ovary-derived fibroblast cell line cell 永生的动物卵巢衍生成纤维细胞系细胞 An immortal fibroblast cell line cell that derives from animal ovary. Yue Liu, Yongqun He An immortal fibroblast cell line cell that derives from animal ovary. Yue Liu, Yongqun He 源自动物卵巢的永生成纤维细胞系细胞。 immortal skin-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from skin. Yue Liu, Yongqun He immortal organism part-derived keratinocyte cell line cell An immortal keratinocyte cell line cell that derives from organism part. Yue Liu, Yongqun He immortal testis-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from testis. Yue Liu, Yongqun He immortal liver-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from liver. Yue Liu, Yongqun He immortal lung-derived fibroblast cell line cell immortal lung-derived fibroblast cell line cell 永生的肺衍生成纤维细胞系细胞 An immortal fibroblast cell line cell that derives from lung. Yue Liu, Yongqun He An immortal fibroblast cell line cell that derives from lung. Yue Liu, Yongqun He 源自肺的永生成纤维细胞系细胞。 immortal embryo-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from embryo. Yue Liu, Yongqun He immortal thoracic aorta-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from thoracic aorta. Yue Liu, Yongqun He immortal gum-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from gum. Yue Liu, Yongqun He immortal digit-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from digit. Yue Liu, Yongqun He immortal skin-derived cell line cell immortal skin-derived cell line cell 永生的皮肤衍生细胞系细胞 An immortal cell line cell that derives from skin. Yue Liu, Yongqun He An immortal cell line cell that derives from skin. Yue Liu, Yongqun He 源自皮肤的永生细胞系细胞。 immortal trachealis-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from trachealis. Yue Liu, Yongqun He immortal neck-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from neck. Yue Liu, Yongqun He immortal umbilical cord-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from umbilical cord. Yue Liu, Yongqun He immortal abdominal aorta-derived endothelial cell line cell An immortal endothelial cell line cell that derives from abdominal aorta. Yue Liu, Yongqun He immortal iliac vein-derived endothelial cell line cell An immortal endothelial cell line cell that derives from iliac vein. Yue Liu, Yongqun He immortal common iliac artery-derived endothelial cell line cell An immortal endothelial cell line cell that derives from common iliac artery. Yue Liu, Yongqun He immortal gonad-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from gonad. Yue Liu, Yongqun He immortal amnion-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from amnion. Yue Liu, Yongqun He immortal thigh-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from thigh. Yue Liu, Yongqun He immortal umbilical vein-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from umbilical vein. Yue Liu, Yongqun He immortal vasculature-derived cell line cell immortal vasculature-derived cell line cell 永生化的血管衍生细胞系细胞 An immortal cell line cell that derives from vasculature. Yue Liu, Yongqun He An immortal cell line cell that derives from vasculature. Yue Liu, Yongqun He 源自血管系统的永生细胞系细胞。 immortal spleen-derived cell line cell An immortal cell line cell that derives from spleen. Yue Liu, Yongqun He immortal multi-cellular organism-derived cell line cell An immortal cell line cell that derives from multi-cellular organism. Yue Liu, Yongqun He immortal fetal membrane-derived cell line cell immortal fetal membrane-derived cell line cell 永生的胎膜衍生细胞系细胞 An immortal cell line cell that derives from fetal membrane. Yue Liu, Yongqun He An immortal cell line cell that derives from fetal membrane. Yue Liu, Yongqun He 源自胎膜的永生细胞系细胞。 immortal dento-alveolar joint-derived cell line cell immortal dento-alveolar joint-derived cell line cell 永生的牙齿-牙槽骨关节衍生细胞系细胞 An immortal cell line cell that derives from dento-alveolar joint. Yue Liu, Yongqun He An immortal cell line cell that derives from dento-alveolar joint. Yue Liu, Yongqun He 源自牙齿-牙槽骨关节的永生细胞系细胞。 immortal mixed endoderm/mesoderm-derived structure-derived cell line cell immortal mixed endoderm/mesoderm-derived structure-derived cell line cell 永生的混合内胚层/中胚层衍生结构衍生的细胞系细胞 An immortal cell line cell that derives from mixed endoderm/mesoderm-derived structure. Yue Liu, Yongqun He An immortal cell line cell that derives from mixed endoderm/mesoderm-derived structure. Yue Liu, Yongqun He 源自混合内胚层/中胚层衍生结构的永生细胞系细胞。 immortal late embryo-derived cell line cell An immortal cell line cell that derives from late embryo. Yue Liu, Yongqun He immortal muscle spindle-derived cell line cell An immortal cell line cell that derives from muscle spindle. Yue Liu, Yongqun He immortal thymus-derived cell line cell immortal thymus-derived cell line cell 永生的胸腺衍生细胞系细胞 An immortal cell line cell that derives from thymus. Yue Liu, Yongqun He An immortal cell line cell that derives from thymus. Yue Liu, Yongqun He 源自胸腺的永生细胞系细胞。 immortal amnion-derived cell line cell An immortal cell line cell that derives from amnion. Yue Liu, Yongqun He immortal tongue-derived cell line cell immortal tongue-derived cell line cell 永生的舌衍生细胞系细胞 An immortal cell line cell that derives from tongue. Yue Liu, Yongqun He An immortal cell line cell that derives from tongue. Yue Liu, Yongqun He 源自舌头的永生细胞系细胞。 immortal lung-derived cell line cell immortal lung-derived cell line cell 永生化的肺衍生细胞系细胞 An immortal cell line cell that derives from pair of lungs. Yue Liu, Yongqun He An immortal cell line cell that derives from pair of lungs. Yue Liu, Yongqun He 源自一对肺的永生细胞系细胞。 immortal kidney-derived cell line cell immortal kidney-derived cell line cell 永生化的肾衍生细胞系细胞 An immortal cell line cell that derives from kidney. Yue Liu, Yongqun He An immortal cell line cell that derives from kidney. Yue Liu, Yongqun He 源自肾的永生细胞系细胞。 immortal abdominal cavity-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from abdominal cavity. Yue Liu, Yongqun He immortal thoracic aorta-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from thoracic aorta. Yue Liu, Yongqun He immortal placenta-derived cell line cell immortal placenta-derived cell line cell 永生化的胎盘衍生细胞系细胞 An immortal cell line cell that derives from placenta. Yue Liu, Yongqun He An immortal cell line cell that derives from placenta. Yue Liu, Yongqun He 源自胎盘的永生细胞系细胞。 immortal pericardium-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from pericardium. Yue Liu, Yongqun He immortal embryo-derived cell line cell immortal embryo-derived cell line cell 永生化的胚胎衍生细胞系细胞 An immortal cell line cell that derives from embryo. Yue Liu, Yongqun He An immortal cell line cell that derives from embryo. Yue Liu, Yongqun He 源自胚胎的永生细胞系细胞。 immortal foetal structure-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from foetal structure. Yue Liu, Yongqun He immortal external genitalia-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from external genitalia. Yue Liu, Yongqun He immortal prostate gland-derived cell line cell immortal prostate gland-derived cell line cell 永生化的前列腺衍生细胞系细胞 An immortal cell line cell that derives from prostate gland. Yue Liu, Yongqun He An immortal cell line cell that derives from prostate gland. Yue Liu, Yongqun He 源自前列腺的永生细胞系细胞。 immortal septum of telencephalon-derived cell line cell immortal septum of telencephalon-derived cell line cell 永生的端脑中隔衍生细胞系细胞 An immortal cell line cell that derives from septum of telencephalon. Yue Liu, Yongqun He An immortal cell line cell that derives from septum of telencephalon. Yue Liu, Yongqun He 源自端脑中隔的永生细胞系细胞。 immortal larva-derived cell line cell immortal larva-derived cell line cell 永生的幼虫衍生细胞系细胞 An immortal cell line cell that derives from larva. Yue Liu, Yongqun He An immortal cell line cell that derives from larva. Yue Liu, Yongqun He 源自幼虫的永生细胞系细胞。 immortal area X-derived cell line cell An immortal cell line cell that derives from area X. Yue Liu, Yongqun He immortal somatic nervous system-derived cell line cell An immortal cell line cell that derives from somatic nervous system. Yue Liu, Yongqun He immortal lymph-derived cell line cell An immortal cell line cell that derives from lymph. Yue Liu, Yongqun He immortal thoracic aorta-derived endothelial cell line cell An immortal endothelial cell line cell that derives from thoracic aorta. Yue Liu, Yongqun He immortal liver-derived cell line cell immortal liver-derived cell line cell 永生的肝衍生细胞系细胞 An immortal cell line cell that derives from liver. Yue Liu, Yongqun He An immortal cell line cell that derives from liver. Yue Liu, Yongqun He 源自肝脏的永生细胞系细胞。 immortal colon-derived cell line cell immortal colon-derived cell line cell 永生的结肠衍生细胞系细胞 An immortal cell line cell that derives from colon. Yue Liu, Yongqun He An immortal cell line cell that derives from colon. Yue Liu, Yongqun He 源自结肠的永生细胞系细胞。 immortal caecum-derived cell line cell immortal caecum-derived cell line cell 永生的盲肠衍生细胞系细胞 An immortal cell line cell that derives from caecum. Yue Liu, Yongqun He An immortal cell line cell that derives from caecum. Yue Liu, Yongqun He 源自盲肠的永生细胞系细胞。 immortal pancreas-derived cell line cell immortal pancreas-derived cell line cell 永生的胰腺衍生细胞系细胞 An immortal cell line cell that derives from pancreas. Yue Liu, Yongqun He An immortal cell line cell that derives from pancreas. Yue Liu, Yongqun He 源自胰腺的永生细胞系细胞。 immortal brain-derived cell line cell immortal brain-derived cell line cell 永生化的大脑衍生细胞系细胞 An immortal cell line cell that derives from brain. Yue Liu, Yongqun He An immortal cell line cell that derives from brain. Yue Liu, Yongqun He 源自大脑的永生细胞系细胞。 immortal tail-derived cell line cell An immortal cell line cell that derives from tail. Yue Liu, Yongqun He immortal collecting duct of renal tubule-derived cell line cell immortal collecting duct of renal tubule-derived cell line cell 永生的肾小管集合管衍生细胞系细胞 An immortal cell line cell that derives from collecting duct of renal tubule. Yue Liu, Yongqun He An immortal cell line cell that derives from collecting duct of renal tubule. Yue Liu, Yongqun He 源自肾小管集合管的永生细胞系细胞。 immortal mesonephros-derived cell line cell An immortal cell line cell that derives from mesonephros. Yue Liu, Yongqun He immortal female gonad-derived cell line cell immortal female gonad-derived cell line cell 永生的雌性性腺衍生细胞系细胞 An immortal cell line cell that derives from female gonad. Yue Liu, Yongqun He An immortal cell line cell that derives from female gonad. Yue Liu, Yongqun He 源自雌性性腺的永生细胞系细胞。 immortal chorion-derived cell line cell An immortal cell line cell that derives from chorion. Yue Liu, Yongqun He immortal lymphoid follicle-derived cell line cell An immortal cell line cell that derives from lymphoid follicle. Yue Liu, Yongqun He immortal leg-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from leg. Yue Liu, Yongqun He immortal limb/fin-derived cell line cell An immortal cell line cell that derives from limb/fin. Yue Liu, Yongqun He immortal testis-derived cell line cell immortal testis-derived cell line cell 永生的睾丸衍生细胞系细胞 An immortal cell line cell that derives from testis. Yue Liu, Yongqun He An immortal cell line cell that derives from testis. Yue Liu, Yongqun He 源自睾丸的永生细胞系细胞。 immortal stomach-derived cell line cell immortal stomach-derived cell line cell 永生化的胃衍生细胞系细胞 An immortal cell line cell that derives from stomach. Yue Liu, Yongqun He An immortal cell line cell that derives from stomach. Yue Liu, Yongqun He 源自胃的永生细胞系细胞。 immortal endothelium-derived cell line cell An immortal cell line cell that derives from endothelium. Yue Liu, Yongqun He immortal foreskin-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from foreskin. Yue Liu, Yongqun He immortal achilles tendon-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from achilles tendon. Yue Liu, Yongqun He immortal bone element-derived cell line cell immortal bone element-derived cell line cell 永生的骨元素衍生细胞系细胞 An immortal cell line cell that derives from bone element. Yue Liu, Yongqun He An immortal cell line cell that derives from bone element. Yue Liu, Yongqun He 源自骨元素的永生细胞系细胞。 immortal thyroid gland-derived cell line cell immortal thyroid gland-derived cell line cell 永生的甲状腺衍生细胞系细胞 An immortal cell line cell that derives from thyroid gland. Yue Liu, Yongqun He An immortal cell line cell that derives from thyroid gland. Yue Liu, Yongqun He 源自甲状腺的永生细胞系细胞。 immortal urinary bladder-derived cell line cell immortal urinary bladder-derived cell line cell 永生的膀胱衍生细胞系细胞 An immortal cell line cell that derives from urinary bladder. Yue Liu, Yongqun He An immortal cell line cell that derives from urinary bladder. Yue Liu, Yongqun He 源自膀胱的永生细胞系细胞。 immortal acetabular part of hip bone-derived cell line cell immortal acetabular part of hip bone-derived cell line cell 髋关节髋臼衍生细胞系细胞 An immortal cell line cell that derives from acetabular part of hip bone. Yue Liu, Yongqun He An immortal cell line cell that derives from acetabular part of hip bone. Yue Liu, Yongqun He 源自髋关节髋臼的永生细胞系细胞 immortal breast-derived cell line cell 永生的乳腺衍生细胞系细胞 immortal breast-derived cell line cell An immortal cell line cell that derives from breast. Yue Liu, Yongqun He An immortal cell line cell that derives from breast. Yue Liu, Yongqun He 源自乳腺的永生细胞系细胞。 immortal epithelium-derived cell line cell An immortal cell line cell that derives from epithelium. Yue Liu, Yongqun He immortal comma-shaped body-derived cell line cell immortal comma-shaped body-derived cell line cell 永生的逗点状体衍生细胞系细胞 An immortal cell line cell that derives from comma-shaped body. Yue Liu, Yongqun He An immortal cell line cell that derives from comma-shaped body. Yue Liu, Yongqun He 源自逗点状体的永生细胞系细胞 immortal supra-orbital vein-derived cell line cell immortal supra-orbital vein-derived cell line cell 永生的眶上静脉衍生细胞系细胞 An immortal cell line cell that derives from supra-orbital vein. Yue Liu, Yongqun He An immortal cell line cell that derives from supra-orbital vein. Yue Liu, Yongqun He 源自眶上静脉的永生细胞系细胞。 immortal ear-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from ear. Yue Liu, Yongqun He immortal inguinal region-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from inguinal region. Yue Liu, Yongqun He immortal mesothelium-derived cell line cell An immortal cell line cell that derives from mesothelium. Yue Liu, Yongqun He immortal uterus-derived cell line cell immortal uterus-derived cell line cell 永生的子宫衍生细胞系细胞 An immortal cell line cell that derives from uterus. Yue Liu, Yongqun He An immortal cell line cell that derives from uterus. Yue Liu, Yongqun He 源自子宫的永生细胞系细胞。 immortal endometrium-derived cell line cell An immortal cell line cell that derives from endometrium. Yue Liu, Yongqun He immortal uterine cervix-derived cell line cell immortal uterine cervix-derived cell line cell 永生的子宫颈衍生细胞系细胞 An immortal cell line cell that derives from uterine cervix. Yue Liu, Yongqun He An immortal cell line cell that derives from uterine cervix. Yue Liu, Yongqun He 源自子宫颈的永生衍生细胞系细胞 immortal heart-derived cell line cell An immortal cell line cell that derives from heart. Yue Liu, Yongqun He immortal pituitary gland-derived cell line cell immortal pituitary gland-derived cell line cell 永生的垂体衍生细胞系细胞 An immortal cell line cell that derives from pituitary gland. Yue Liu, Yongqun He An immortal cell line cell that derives from pituitary gland. Yue Liu, Yongqun He 源自垂体的永生细胞系细胞。 immortal gill-derived cell line cell An immortal cell line cell that derives from gill. Yue Liu, Yongqun He immortal follicular fluid-derived cell line cell An immortal cell line cell that derives from follicular fluid. Yue Liu, Yongqun He immortal eye-derived cell line cell immortal eye-derived cell line cell 永生化的眼衍生细胞系细胞 An immortal cell line cell that derives from eye. Yue Liu, Yongqun He An immortal cell line cell that derives from eye. Yue Liu, Yongqun He 源自眼的永生细胞系细胞。 immortal organism part-derived plasma cell line cell immortal organism part-derived plasma cell line cell 永生的生物部分衍生的浆细胞系细胞 An immortal plasma cell line cell that derives from organism part. Yue Liu, Yongqun He An immortal plasma cell line cell that derives from organism part. Yue Liu, Yongqun He 源自生物体部分的永生浆细胞系细胞。 immortal floating rib-derived cell line cell An immortal cell line cell that derives from floating rib. Yue Liu, Yongqun He immortal mammary gland-derived cell line cell An immortal cell line cell that derives from mammary gland. Yue Liu, Yongqun He immortal thorax-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from thorax. Yue Liu, Yongqun He immortal paired fin-derived cell line cell An immortal cell line cell that derives from paired fin. Yue Liu, Yongqun He immortal neural nucleus-derived cell line cell immortal neural nucleus-derived cell line cell 永生的神经核衍生细胞系细胞 An immortal cell line cell that derives from neural nucleus. Yue Liu, Yongqun He An immortal cell line cell that derives from neural nucleus. Yue Liu, Yongqun He 源自神经核的永生细胞系细胞。 immortal Ammon's horn-derived cell line cell An immortal cell line cell that derives from Ammon's horn. Yue Liu, Yongqun He immortal bone marrow-derived cell line cell An immortal cell line cell that derives from bone marrow. Yue Liu, Yongqun He immortal islet of Langerhans-derived cell line cell immortal islet of Langerhans-derived cell line cell 永生的胰岛衍生细胞系细胞 An immortal cell line cell that derives from islet of Langerhans. Yue Liu, Yongqun He An immortal cell line cell that derives from islet of Langerhans. Yue Liu, Yongqun He 源自胰岛的永生细胞系细胞。 immortal pyramid of medulla oblongata-derived cell line cell An immortal cell line cell that derives from pyramid of medulla oblongata. Yue Liu, Yongqun He mouse x mouse hybridoma cell line cell 小鼠x小鼠杂交瘤细胞系细胞 Yongqun He a hybridoma cell line cell that is established by fusing cells from two mice. a hybridoma cell line cell that is established by fusing cells from two mice. 大部分杂交瘤细胞是小鼠x小鼠 most hybridoma cell line cells are mouse x mouse Yongqun He most hybridoma cell line cells are mouse x mouse 通过融合来自两只小鼠的细胞建立的杂交瘤细胞系细胞。 immortal uterine cervix-derived epithelial cell line cell immortal uterine cervix-derived epithelial cell line cell 永生的宫颈衍生上皮细胞系细胞 An immortal epithelial cell line cell that derives from uterine cervix. Yue Liu, Yongqun He An immortal epithelial cell line cell that derives from uterine cervix. Yue Liu, Yongqun He 源自子宫颈的永生上皮细胞系细胞。 immortal ileocecal junction-derived cell line cell immortal ileocecal junction-derived cell line cell 永生的回盲连接衍生细胞系细胞 An immortal cell line cell that derives from ileocecal junction. Yue Liu, Yongqun He An immortal cell line cell that derives from ileocecal junction. Yue Liu, Yongqun He 源自回盲连接的永生细胞系细胞。 immortal compact bone-derived cell line cell An immortal cell line cell that derives from compact bone. Yue Liu, Yongqun He immortal abdominal aorta-derived cell line cell An immortal cell line cell that derives from abdominal aorta. Yue Liu, Yongqun He immortal bronchus-derived cell line cell An immortal cell line cell that derives from bronchus. Yue Liu, Yongqun He immortal iliac artery-derived cell line cell An immortal cell line cell that derives from iliac artery. Yue Liu, Yongqun He immortal synovial membrane of synovial joint-derived cell line cell An immortal cell line cell that derives from synovial membrane of synovial joint. Yue Liu, Yongqun He immortal iliac vein-derived cell line cell An immortal cell line cell that derives from iliac vein. Yue Liu, Yongqun He immortal vagina-derived cell line cell An immortal cell line cell that derives from vagina. Yue Liu, Yongqun He immortal larynx-derived cell line cell immortal larynx-derived cell line cell 永生的喉衍生细胞系细胞 An immortal cell line cell that derives from larynx. Yue Liu, Yongqun He An immortal cell line cell that derives from larynx. Yue Liu, Yongqun He 源自喉的永生细胞系细胞。 immortal inferior cervical ganglion-derived cell line cell An immortal cell line cell that derives from inferior cervical ganglion. Yue Liu, Yongqun He immortal esophagus-derived cell line cell immortal esophagus-derived cell line cell 永生的食管衍生细胞系细胞 An immortal cell line cell that derives from esophagus. Yue Liu, Yongqun He An immortal cell line cell that derives from esophagus. Yue Liu, Yongqun He 源自食管的永生细胞系细胞。 immortal femoral artery-derived cell line cell An immortal cell line cell that derives from femoral artery. Yue Liu, Yongqun He immortal prepuce of penis-derived cell line cell An immortal cell line cell that derives from prepuce of penis. Yue Liu, Yongqun He immortal gingival epithelium-derived cell line cell An immortal cell line cell that derives from gingival epithelium. Yue Liu, Yongqun He immortal gingiva-derived cell line cell An immortal cell line cell that derives from gingiva. Yue Liu, Yongqun He immortal mouth-derived cell line cell An immortal cell line cell that derives from mouth. Yue Liu, Yongqun He immortal peripheral vein-derived cell line cell An immortal cell line cell that derives from peripheral vein. Yue Liu, Yongqun He immortal peritoneum-derived cell line cell An immortal cell line cell that derives from peritoneum. Yue Liu, Yongqun He immortal round window-derived cell line cell immortal round window-derived cell line cell 永生的圆窗衍生细胞系细胞 An immortal cell line cell that derives from round window. Yue Liu, Yongqun He An immortal cell line cell that derives from round window. Yue Liu, Yongqun He 源自圆窗的永生细胞系细胞。 immortal conjunctiva structure-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from conjunctiva structure. Yue Liu, Yongqun He immortal intestine-derived cell line cell immortal intestine-derived cell line cell 永生的肠衍生细胞系细胞 An immortal cell line cell that derives from intestine. Yue Liu, Yongqun He An immortal cell line cell that derives from intestine. Yue Liu, Yongqun He 源自肠的永生细胞系细胞。 immortal rectum-derived cell line cell An immortal cell line cell that derives from rectum. Yue Liu, Yongqun He immortal pulmonary vein-derived cell line cell An immortal cell line cell that derives from pulmonary vein. Yue Liu, Yongqun He immortal buttock-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from buttock. Yue Liu, Yongqun He immortal tonsil-derived cell line cell An immortal cell line cell that derives from tonsil. Yue Liu, Yongqun He immortal umbilicus-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from umbilicus. Yue Liu, Yongqun He immortal posterior commissure-derived cell line cell immortal posterior commissure-derived cell line cell 永生的后连合衍生细胞系细胞 An immortal cell line cell that derives from posterior commissure. Yue Liu, Yongqun He An immortal cell line cell that derives from posterior commissure. Yue Liu, Yongqun He 源自后连合的永生细胞系细胞。 immortal soft palate-derived cell line cell An immortal cell line cell that derives from soft palate. Yue Liu, Yongqun He immortal adrenal gland-derived cell line cell immortal adrenal gland-derived cell line cell 永生的肾上腺衍生细胞系细胞 An immortal cell line cell that derives from adrenal gland. Yue Liu, Yongqun He An immortal cell line cell that derives from adrenal gland. Yue Liu, Yongqun He 源自肾上腺的永生细胞系细胞。 immortal pronephros-derived cell line cell An immortal cell line cell that derives from pronephros. Yue Liu, Yongqun He immortal organism part-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from organism part. Yue Liu, Yongqun He immortal sublingual artery-derived cell line cell An immortal cell line cell that derives from sublingual artery. Yue Liu, Yongqun He immortal aorta-derived cell line cell immortal aorta-derived cell line cell 永生的主动脉衍生细胞系细胞 An immortal cell line cell that derives from aorta. Yue Liu, Yongqun He An immortal cell line cell that derives from aorta. Yue Liu, Yongqun He 源自主动脉的永生细胞系细胞。 immortal ligament-derived cell line cell An immortal cell line cell that derives from ligament. Yue Liu, Yongqun He immortal uterus-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from uterus. Yue Liu, Yongqun He immortal cerebral lobe-derived cell line cell An immortal cell line cell that derives from cerebral lobe. Yue Liu, Yongqun He immortal squamous part of temporal bone-derived cell line cell An immortal cell line cell that derives from squamous part of temporal bone. Yue Liu, Yongqun He immortal pronephros-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from pronephros. Yue Liu, Yongqun He immortal mucosa-derived cell line cell An immortal cell line cell that derives from mucosa. Yue Liu, Yongqun He immortal epidermis-derived cell line cell An immortal cell line cell that derives from epidermis. Yue Liu, Yongqun He immortal submandibular gland-derived cell line cell An immortal cell line cell that derives from submandibular gland. Yue Liu, Yongqun He immortal lung-derived mesothelial cell line cell An immortal mesothelial cell line cell that derives from lung. Yue Liu, Yongqun He immortal eye structure-derived epithelial cell line cell An immortal epithelial cell line cell that derives from eye structure. Yue Liu, Yongqun He immortal hip-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from hip. Yue Liu, Yongqun He immortal prostate epithelium-derived cell line cell immortal prostate epithelium-derived cell line cell 永生的前列腺上皮衍生细胞系细胞 An immortal cell line cell that derives from prostate epithelium. Yue Liu, Yongqun He An immortal cell line cell that derives from prostate epithelium. Yue Liu, Yongqun He 源自前列腺上皮的永生细胞系细胞。 immortal retinal neural layer-derived cell line cell An immortal cell line cell that derives from retinal neural layer. Yue Liu, Yongqun He immortal ureter-derived cell line cell An immortal cell line cell that derives from ureter. Yue Liu, Yongqun He immortal iliac vein-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from iliac vein. Yue Liu, Yongqun He immortal common iliac artery-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from common iliac artery. Yue Liu, Yongqun He immortal mammary gland-derived keratinocyte cell line cell An immortal keratinocyte cell line cell that derives from mammary gland. Yue Liu, Yongqun He immortal umbilical vein-derived endothelial cell line cell An immortal endothelial cell line cell that derives from umbilical vein. Yue Liu, Yongqun He immortal scalp-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from scalp. Yue Liu, Yongqun He immortal skeletal muscle-derived myoblast cell line cell An immortal myoblast cell line cell that derives from skeletal muscle. Yue Liu, Yongqun He immortal organism part-derived endothelial cell line cell An immortal endothelial cell line cell that derives from organism part. Yue Liu, Yongqun He immortal sacrum-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from sacrum. Yue Liu, Yongqun He immortal shoulder-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from shoulder. Yue Liu, Yongqun He immortal placenta-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from placenta. Yue Liu, Yongqun He immortal dermis-derived cell line cell An immortal cell line cell that derives from dermis. Yue Liu, Yongqun He immortal cornea-derived cell line cell An immortal cell line cell that derives from cornea. Yue Liu, Yongqun He immortal mammalian vulva-derived cell line cell An immortal cell line cell that derives from mammalian vulva. Yue Liu, Yongqun He immortal spherical lensed eye-derived cell line cell immortal spherical lensed eye-derived cell line cell 永生的球面透镜眼衍生细胞系细胞 An immortal cell line cell that derives from spherical lensed eye. Yue Liu, Yongqun He An immortal cell line cell that derives from spherical lensed eye. Yue Liu, Yongqun He 源自球面透镜眼的永生细胞系细胞。 immortal ileum-derived cell line cell An immortal cell line cell that derives from ileum. Yue Liu, Yongqun He immortal cervix-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from cervix. Yue Liu, Yongqun He immortal rhomboid-derived myoblast cell line cell An immortal myoblast cell line cell that derives from rhomboid. Yue Liu, Yongqun He immortal abdominal cavity-derived cell line cell An immortal cell line cell that derives from abdominal cavity. Yue Liu, Yongqun He immortal umbilical vein-derived cell line cell An immortal cell line cell that derives from umbilical vein. Yue Liu, Yongqun He immortal duodenum-derived cell line cell An immortal cell line cell that derives from duodenum. Yue Liu, Yongqun He immortal connective tissue-derived cell line cell immortal connective tissue-derived cell line cell 永生的结缔组织衍生细胞系细胞 An immortal cell line cell that derives from connective tissue. Yue Liu, Yongqun He An immortal cell line cell that derives from connective tissue. Yue Liu, Yongqun He 源自结缔组织的永生细胞系细胞。 immortal parotid gland-derived cell line cell An immortal cell line cell that derives from parotid gland. Yue Liu, Yongqun He immortal ischium-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from ischium. Yue Liu, Yongqun He immortal buttock-derived cell line cell An immortal cell line cell that derives from buttock. Yue Liu, Yongqun He immortal anatomical cluster-derived cell line cell immortal anatomical cluster-derived cell line cell 永生的解剖簇衍生细胞系细胞 An immortal cell line cell that derives from anatomical cluster. Yue Liu, Yongqun He An immortal cell line cell that derives from anatomical cluster. Yue Liu, Yongqun He 源自解剖簇的永生细胞系细胞。 immortal thigh-derived cell line cell An immortal cell line cell that derives from thigh. Yue Liu, Yongqun He immortal chordate pharynx-derived cell line cell immortal chordate pharynx-derived cell line cell 永生的脊索动物咽衍生细胞系细胞 An immortal cell line cell that derives from chordate pharynx. Yue Liu, Yongqun He An immortal cell line cell that derives from chordate pharynx. Yue Liu, Yongqun He 来自脊索动物咽的永生细胞系细胞。 immortal retina-derived cell line cell immortal retina-derived cell line cell 永生的视网膜衍生细胞系细胞 An immortal cell line cell that derives from retina. Yue Liu, Yongqun He An immortal cell line cell that derives from retina. Yue Liu, Yongqun He 源自视网膜的永生细胞系细胞。 immortal yolk sac-derived cell line cell An immortal cell line cell that derives from yolk sac. Yue Liu, Yongqun He immortal nasal concha-derived cell line cell immortal nasal concha-derived cell line cell 永生的鼻甲衍生细胞系细胞 An immortal cell line cell that derives from nasal concha. Yue Liu, Yongqun He An immortal cell line cell that derives from nasal concha. Yue Liu, Yongqun He 源自鼻甲的永生细胞系细胞。 immortal arm-derived cell line cell An immortal cell line cell that derives from arm. Yue Liu, Yongqun He immortal sacrum-derived cell line cell An immortal cell line cell that derives from sacrum. Yue Liu, Yongqun He immortal conjunctiva-derived cell line cell An immortal cell line cell that derives from conjunctiva. Yue Liu, Yongqun He immortal trachea-derived cell line cell immortal trachea-derived cell line cell 永生的气管衍生细胞系细胞 An immortal cell line cell that derives from trachea. Yue Liu, Yongqun He An immortal cell line cell that derives from trachea. Yue Liu, Yongqun He 源自气管的永生细胞系细胞。 immortal respiration organ-derived cell line cell An immortal cell line cell that derives from respiration organ. Yue Liu, Yongqun He immortal renal glomerulus-derived cell line cell immortal renal glomerulus-derived cell line cell 永生的肾小球衍生细胞系细胞 An immortal cell line cell that derives from renal glomerulus. Yue Liu, Yongqun He An immortal cell line cell that derives from renal glomerulus. Yue Liu, Yongqun He 源自肾小球的永生细胞系细胞。 immortal nephron tubule-derived cell line cell An immortal cell line cell that derives from nephron tubule. Yue Liu, Yongqun He immortal sternum-derived cell line cell An immortal cell line cell that derives from sternum. Yue Liu, Yongqun He immortal hypodermis-derived cell line cell An immortal cell line cell that derives from hypodermis. Yue Liu, Yongqun He immortal proximal tubule-derived cell line cell An immortal cell line cell that derives from proximal tubule. Yue Liu, Yongqun He immortal mucosa of vagina-derived cell line cell An immortal cell line cell that derives from mucosa of vagina. Yue Liu, Yongqun He immortal endocervix-derived cell line cell An immortal cell line cell that derives from endocervix. Yue Liu, Yongqun He immortal organism part-derived mesothelial cell line cell An immortal mesothelial cell line cell that derives from organism part. Yue Liu, Yongqun He immortal human peripheral vein-derived B cell line cell immortal human peripheral vein-derived B cell line cell 永生的人外周静脉衍生B细胞系细胞 An immortal peripheral vein-derived B cell line cell that derives from human. Yue Liu, Yongqun He An immortal peripheral vein-derived B cell line cell that derives from human. Yue Liu, Yongqun He 来自人的永生外周静脉衍生B细胞系细胞 immortal pulmonary nerve plexus-derived cell line cell An immortal cell line cell that derives from pulmonary nerve plexus. Yue Liu, Yongqun He immortal pelvic fin-derived cell line cell An immortal cell line cell that derives from pelvic fin. Yue Liu, Yongqun He immortal right ureter-derived cell line cell An immortal cell line cell that derives from right ureter. Yue Liu, Yongqun He immortal superior rostral sulcus-derived cell line cell An immortal cell line cell that derives from superior rostral sulcus. Yue Liu, Yongqun He immortal gonad-derived cell line cell An immortal cell line cell that derives from gonad. Yue Liu, Yongqun He immortal cornea structure-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from cornea structure. Yue Liu, Yongqun He immortal glomerular capsule-derived cell line cell An immortal cell line cell that derives from glomerular capsule. Yue Liu, Yongqun He immortal nasal vestibule-derived cell line cell An immortal cell line cell that derives from nasal vestibule. Yue Liu, Yongqun He immortal adrenal cortex-derived cell line cell immortal adrenal cortex-derived cell line cell 永生的肾上腺皮质衍生细胞系细胞 An immortal cell line cell that derives from adrenal cortex. Yue Liu, Yongqun He An immortal cell line cell that derives from adrenal cortex. Yue Liu, Yongqun He 源自肾上腺皮质的永生细胞系细胞。 immortal 16914-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from 16914. Yue Liu, Yongqun He immortal organism part-derived epithelial cell line cell An immortal epithelial cell line cell that derives from organism part. Yue Liu, Yongqun He immortal axilla-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from axilla. Yue Liu, Yongqun He immortal pulmonary artery-derived endothelial cell line cell An immortal endothelial cell line cell that derives from pulmonary artery. Yue Liu, Yongqun He immortal pulmonary artery-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from pulmonary artery. Yue Liu, Yongqun He immortal retina structure-derived epithelial cell line cell An immortal epithelial cell line cell that derives from retina structure. Yue Liu, Yongqun He immortal calf-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from calf. Yue Liu, Yongqun He immortal nose structure-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from nose structure. Yue Liu, Yongqun He immortal carotid artery-derived smooth muscle cell line cell An immortal smooth muscle cell line cell that derives from carotid artery. Yue Liu, Yongqun He immortal brain-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from brain. Yue Liu, Yongqun He immortal chimpanzee peripheral vein-derived B cell line cell An immortal peripheral vein-derived B cell line cell that derives from chimpanzee. Yue Liu, Yongqun He immortal human arm-derived fibroblast cell line cell An immortal arm-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human organism part-derived fibroblast cell line cell An immortal organism part-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal cattle organism part-derived fibroblast cell line cell An immortal organism part-derived fibroblast cell line cell that derives from cattle. Yue Liu, Yongqun He immortal human tunica albuginea of testis-derived fibroblast cell line cell An immortal tunica albuginea of testis-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human amniotic fluid-derived cell line cell An immortal amniotic fluid-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal human peripheral vein-derived T cell line cell immortal human peripheral vein-derived T cell line cell 永生的人外周静脉衍生T细胞系细胞 An immortal peripheral vein-derived T cell line cell that derives from human. Yue Liu, Yongqun He An immortal peripheral vein-derived T cell line cell that derives from human. Yue Liu, Yongqun He 来自人的永生外周静脉衍生T细胞系细胞 immortal rat organism part-derived cell line cell An immortal organism part-derived cell line cell that derives from rat. Yue Liu, Yongqun He immortal chimpanzee organism part-derived fibroblast cell line cell An immortal organism part-derived fibroblast cell line cell that derives from chimpanzee. Yue Liu, Yongqun He immortal Chinese hamster ovary-derived fibroblast cell line cell immortal Chinese hamster ovary-derived fibroblast cell line cell 永生的中国仓鼠卵巢衍生成纤维细胞系细胞 An immortal animal ovary-derived fibroblast cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He An immortal animal ovary-derived fibroblast cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He 源自中国仓鼠的永生动物卵巢衍生成纤维细胞系细胞。 immortal Bornean orangutan skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Bornean orangutan. Yue Liu, Yongqun He immortal pig-tailed macaque skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from pig-tailed macaque. Yue Liu, Yongqun He immortal Kenya baboon skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Kenya baboon. Yue Liu, Yongqun He immortal long-tailed macaque organism part-derived cell line cell An immortal organism part-derived cell line cell that derives from long-tailed macaque. Yue Liu, Yongqun He immortal pig-tailed macaque organism part-derived keratinocyte cell line cell An immortal organism part-derived keratinocyte cell line cell that derives from pig-tailed macaque. Yue Liu, Yongqun He immortal long-tailed macaque organism part-derived keratinocyte cell line cell An immortal organism part-derived keratinocyte cell line cell that derives from long-tailed macaque. Yue Liu, Yongqun He immortal human testis-derived fibroblast cell line cell An immortal testis-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal pygmy chimpanzee skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from pygmy chimpanzee. Yue Liu, Yongqun He immortal human liver-derived fibroblast cell line cell An immortal liver-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal red-bellied lemur skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from red-bellied lemur. Yue Liu, Yongqun He immortal black lemur skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from black lemur. Yue Liu, Yongqun He immortal Kenya baboon organism part-derived keratinocyte cell line cell An immortal organism part-derived keratinocyte cell line cell that derives from Kenya baboon. Yue Liu, Yongqun He immortal variegated lemur skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from variegated lemur. Yue Liu, Yongqun He immortal small-eared galago skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from small-eared galago. Yue Liu, Yongqun He immortal western gorilla skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from western gorilla. Yue Liu, Yongqun He immortal Angolan colobus skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Angolan colobus. Yue Liu, Yongqun He immortal mouse organism part-derived fibroblast cell line cell An immortal organism part-derived fibroblast cell line cell that derives from mouse. Yue Liu, Yongqun He immortal Colobus guereza skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Colobus guereza. Yue Liu, Yongqun He immortal pygmy chimpanzee peripheral vein-derived B cell line cell An immortal peripheral vein-derived B cell line cell that derives from pygmy chimpanzee. Yue Liu, Yongqun He immortal Allen's swamp monkey skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Allen's swamp monkey. Yue Liu, Yongqun He immortal human lung-derived fibroblast cell line cell immortal human lung-derived fibroblast cell line cell 永生化的人肺衍生成纤维细胞系细胞 An immortal lung-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He An immortal lung-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生肺衍生成纤维细胞系细胞。 immortal mongoose lemur skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from mongoose lemur. Yue Liu, Yongqun He immortal Ring-tailed lemur skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Ring-tailed lemur. Yue Liu, Yongqun He immortal chimpanzee skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from chimpanzee. Yue Liu, Yongqun He immortal rhesus macaque skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from rhesus macaque. Yue Liu, Yongqun He immortal black-handed spider monkey skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from black-handed spider monkey. Yue Liu, Yongqun He immortal Chinese hamster embryo-derived fibroblast cell line cell An immortal embryo-derived fibroblast cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He immortal rat thoracic aorta-derived fibroblast cell line cell An immortal thoracic aorta-derived fibroblast cell line cell that derives from rat. Yue Liu, Yongqun He immortal Charles Island giant tortoise skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from Charles Island giant tortoise. Yue Liu, Yongqun He immortal rat testis-derived fibroblast cell line cell An immortal testis-derived fibroblast cell line cell that derives from rat. Yue Liu, Yongqun He immortal human gum-derived fibroblast cell line cell An immortal gum-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal mouse organism part-derived cell line cell An immortal organism part-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal human digit-derived fibroblast cell line cell An immortal digit-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human skin-derived cell line cell immortal human skin-derived cell line cell 永生化的人皮肤衍生细胞系细胞 An immortal skin-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal skin-derived cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生皮肤衍生的细胞系细胞。 immortal Indian muntjac organism part-derived fibroblast cell line cell An immortal organism part-derived fibroblast cell line cell that derives from Indian muntjac. Yue Liu, Yongqun He immortal human organism part-derived cell line cell immortal human organism part-derived cell line cell 永生化的人生物部分衍生细胞系细胞 An immortal organism part-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal organism part-derived cell line cell that derives from human. Yue Liu, Yongqun He 源于人的永生生物部分衍生细胞系细胞。 immortal European rabbit, rabbit trachealis-derived smooth muscle cell line cell An immortal trachealis-derived smooth muscle cell line cell that derives from European rabbit, rabbit. Yue Liu, Yongqun He immortal human neck-derived fibroblast cell line cell An immortal neck-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human umbilical cord-derived fibroblast cell line cell An immortal umbilical cord-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal lesser panda skin-derived fibroblast cell line cell An immortal skin-derived fibroblast cell line cell that derives from lesser panda. Yue Liu, Yongqun He immortal human abdominal aorta-derived endothelial cell line cell An immortal abdominal aorta-derived endothelial cell line cell that derives from human. Yue Liu, Yongqun He immortal human iliac vein-derived endothelial cell line cell An immortal iliac vein-derived endothelial cell line cell that derives from human. Yue Liu, Yongqun He immortal human common iliac artery-derived endothelial cell line cell An immortal common iliac artery-derived endothelial cell line cell that derives from human. Yue Liu, Yongqun He immortal human embryo-derived fibroblast cell line cell An immortal embryo-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human gonad-derived fibroblast cell line cell An immortal gonad-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human amnion-derived fibroblast cell line cell An immortal amnion-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human thigh-derived fibroblast cell line cell An immortal thigh-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human umbilical vein-derived fibroblast cell line cell An immortal umbilical vein-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal cattle cell line cell An immortal cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle vasculature-derived cell line cell An immortal vasculature-derived cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cat spleen-derived cell line cell An immortal spleen-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat fibroblast cell line cell An immortal fibroblast cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat cell line cell 永生的猫细胞系细胞 An immortal cell line cell that derives from cat. Yue Liu, Yongqun He An immortal cell line cell that derives from cat. Yue Liu, Yongqun He 源自猫的永生细胞系细胞。 immortal cat multi-cellular organism-derived cell line cell An immortal multi-cellular organism-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cattle fetal membrane-derived cell line cell An immortal fetal membrane-derived cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle spleen-derived cell line cell An immortal spleen-derived cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle dento-alveolar joint-derived cell line cell An immortal dento-alveolar joint-derived cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle mixed endoderm/mesoderm-derived structure-derived cell line cell An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cat late embryo-derived cell line cell An immortal late embryo-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat muscle spindle-derived cell line cell An immortal muscle spindle-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat thymus-derived cell line cell An immortal thymus-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal human amnion-derived cell line cell An immortal amnion-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal cat skin-derived cell line cell An immortal skin-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal human lymphocyte cell line cell immortal human lymphocyte cell line cell 永生的人淋巴细胞系细胞 An immortal lymphocyte cell line cell that derives from human. Yue Liu, Yongqun He An immortal lymphocyte cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生淋巴细胞系细胞。 immortal cat mixed endoderm/mesoderm-derived structure-derived cell line cell An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat tongue-derived cell line cell An immortal tongue-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat pair of lungs-derived cell line cell An immortal pair of lungs-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat fetal membrane-derived cell line cell An immortal fetal membrane-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal cat kidney-derived cell line cell immortal cat kidney-derived cell line cell 永生的猫肾衍生细胞系细胞 An immortal kidney-derived cell line cell that derives from cat. Yue Liu, Yongqun He An immortal kidney-derived cell line cell that derives from cat. Yue Liu, Yongqun He 源自猫的永生的肾衍生细胞系细胞。 immortal dog lung-derived fibroblast cell line cell An immortal lung-derived fibroblast cell line cell that derives from dog. Yue Liu, Yongqun He immortal dog abdominal cavity-derived fibroblast cell line cell An immortal abdominal cavity-derived fibroblast cell line cell that derives from dog. Yue Liu, Yongqun He immortal dog thoracic aorta-derived smooth muscle cell line cell An immortal thoracic aorta-derived smooth muscle cell line cell that derives from dog. Yue Liu, Yongqun He immortal cat placenta-derived cell line cell An immortal placenta-derived cell line cell that derives from cat. Yue Liu, Yongqun He immortal rat skin-derived cell line cell An immortal skin-derived cell line cell that derives from rat. Yue Liu, Yongqun He immortal human fibroblast cell line cell immortal human fibroblast cell line cell 永生的人成纤维细胞系细胞 An immortal fibroblast cell line cell that derives from human. Yue Liu, Yongqun He An immortal fibroblast cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生成纤维细胞系细胞。 immortal human pericardium-derived fibroblast cell line cell An immortal pericardium-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal cat embryo-derived cell line cell immortal cat embryo-derived cell line cell 永生的猫胚胎衍生细胞系细胞 An immortal embryo-derived cell line cell that derives from cat. Yue Liu, Yongqun He An immortal embryo-derived cell line cell that derives from cat. Yue Liu, Yongqun He 源自猫的永生胚胎衍生的细胞系细胞。 immortal European rabbit, rabbit embryo-derived cell line cell An immortal embryo-derived cell line cell that derives from European rabbit, rabbit. Yue Liu, Yongqun He cell line cell growth Yongqun He a cell growth where the cell is a cell line cell. immortal cat mononuclear phagocyte cell line cell An immortal mononuclear phagocyte cell line cell that derives from cat. Yue Liu, Yongqun He immortal human foetal structure-derived fibroblast cell line cell An immortal foetal structure-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human external genitalia-derived fibroblast cell line cell An immortal external genitalia-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal rat prostate gland-derived cell line cell An immortal prostate gland-derived cell line cell that derives from rat. Yue Liu, Yongqun He immortal human septum of telencephalon-derived cell line cell - Obsolete immortal human septum of telencephalon-derived cell line cell 端脑衍生细胞系细胞的永生化人间隔 An immortal septum of telencephalon-derived cell line cell that derives from human. Yue Liu, Yongqun He Obsolete - many cell line cells were previously mistakenly assigned under this class. Now no cell line cells available under this class. An immortal septum of telencephalon-derived cell line cell that derives from human. Yue Liu, Yongqun He 来自人的端脑中隔衍生细胞系细胞。 immortal cabbage moth larva-derived cell line cell An immortal larva-derived cell line cell that derives from cabbage moth. Yue Liu, Yongqun He immortal human mixed endoderm/mesoderm-derived structure-derived cell line cell immortal human mixed endoderm/mesoderm-derived structure-derived cell line cell 永生的人混合内胚层/中胚层衍生结构衍生的细胞系细胞 An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from human. Yue Liu, Yongqun He 来自人的永生混合内胚层/中胚层衍生结构衍生的细胞系细胞。 immortal monkey kidney-derived cell line cell immortal monkey kidney-derived cell line cell 永生化的猴肾衍生细胞系细胞 An immortal kidney-derived cell line cell that derives from monkey. Yue Liu, Yongqun He An immortal kidney-derived cell line cell that derives from monkey. Yue Liu, Yongqun He 源自猴子的永生肾衍生细胞系细胞。 immortal mouse lymphocyte cell line cell An immortal lymphocyte cell line cell that derives from mouse. Yue Liu, Yongqun He immortal human lung-derived cell line cell immortal human lung-derived cell line cell 永生的人肺衍生细胞系细胞 An immortal lung-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal lung-derived cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生肺衍生细胞系细胞。 immortal mouse pair of lungs-derived cell line cell immortal mouse pair of lungs-derived cell line cell 永生的小鼠肺对衍生细胞系细胞 An immortal pair of lungs-derived cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal pair of lungs-derived cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生肺对衍生细胞系细胞。 immortal mouse area X-derived cell line cell An immortal area X-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal Mus musculus x Rattus norvegicus area X-derived cell line cell An immortal area X-derived cell line cell that derives from Mus musculus x Rattus norvegicus. Yue Liu, Yongqun He immortal Chinese hamster somatic nervous system-derived cell line cell An immortal somatic nervous system-derived cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He mouse x rat hybridoma cell line cell Yongqun He a hybridoma cell line cell that is established by fusing cells from a mouse and a rat. immortal mouse fibroblast cell line cell immortal mouse fibroblast cell line cell 永生的小鼠成纤维细胞系细胞 An immortal fibroblast cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal fibroblast cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生成纤维细胞系细胞。 immortal common quail cell line cell An immortal cell line cell that derives from common quail. Yue Liu, Yongqun He immortal mouse lymph-derived cell line cell An immortal lymph-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal mouse multi-cellular organism-derived cell line cell An immortal multi-cellular organism-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal mouse embryo-derived cell line cell immortal mouse embryo-derived cell line cell 永生的小鼠胚胎衍生细胞系细胞 An immortal embryo-derived cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal embryo-derived cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生胚胎衍生的细胞系细胞。 immortal turnip moth embryo-derived cell line cell An immortal embryo-derived cell line cell that derives from turnip moth. Yue Liu, Yongqun He immortal cattle thoracic aorta-derived endothelial cell line cell An immortal thoracic aorta-derived endothelial cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle lung-derived fibroblast cell line cell An immortal lung-derived fibroblast cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle thoracic aorta-derived smooth muscle cell line cell An immortal thoracic aorta-derived smooth muscle cell line cell that derives from cattle. Yue Liu, Yongqun He immortal cattle thigh-derived fibroblast cell line cell An immortal thigh-derived fibroblast cell line cell that derives from cattle. Yue Liu, Yongqun He immortal pig thoracic aorta-derived smooth muscle cell line cell An immortal thoracic aorta-derived smooth muscle cell line cell that derives from pig. Yue Liu, Yongqun He immortal Syrian golden hamster induced T-regulatory cell line cell An immortal induced T-regulatory cell line cell that derives from Syrian golden hamster. Yue Liu, Yongqun He immortal human cell line cell immortal human cell line cell 永生的人细胞系细胞 An immortal cell line cell that derives from human. Yue Liu, Yongqun He An immortal cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生细胞系细胞。 immortal rat liver-derived cell line cell immortal rat liver-derived cell line cell 永生的大鼠肝衍生细胞系细胞 An immortal liver-derived cell line cell that derives from rat. Yue Liu, Yongqun He An immortal liver-derived cell line cell that derives from rat. Yue Liu, Yongqun He 源自大鼠的永生肝衍生细胞系细胞。 immortal human colon-derived cell line cell immortal human colon-derived cell line cell 永生化的人结肠衍生细胞系细胞 An immortal colon-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal colon-derived cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生结肠衍生细胞系细胞。 immortal human caecum-derived cell line cell immortal human caecum-derived cell line cell 永生的人盲肠衍生细胞系细胞 An immortal caecum-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal caecum-derived cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生盲肠衍生细胞系细胞。 immortal mouse pancreas-derived cell line cell An immortal pancreas-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal pig-tailed macaque lung-derived fibroblast cell line cell An immortal lung-derived fibroblast cell line cell that derives from pig-tailed macaque. Yue Liu, Yongqun He immortal human brain-derived cell line cell immortal human brain-derived cell line cell 永生的人大脑衍生细胞系细胞 An immortal brain-derived cell line cell that derives from human. Yue Liu, Yongqun He An immortal brain-derived cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生大脑衍生细胞系细胞。 immortal human trophoblast cell line cell An immortal trophoblast cell line cell that derives from human. Yue Liu, Yongqun He immortal mouse tail-derived cell line cell An immortal tail-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal mouse skin-derived cell line cell immortal mouse skin-derived cell line cell 永生的小鼠皮肤衍生细胞系细胞 An immortal skin-derived cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal skin-derived cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生皮肤衍生细胞系细胞。 immortal mouse collecting duct of renal tubule-derived cell line cell immortal mouse collecting duct of renal tubule-derived cell line cell 永生的小鼠肾小管集合管衍生细胞系细胞 An immortal collecting duct of renal tubule-derived cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal collecting duct of renal tubule-derived cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生肾小管集合管衍生细胞系细胞 immortal mouse myeloblast cell line cell An immortal myeloblast cell line cell that derives from mouse. Yue Liu, Yongqun He immortal human peripheral neuron cell line cell immortal human peripheral neuron cell line cell 永生的人外周神经元细胞系细胞 An immortal peripheral neuron cell line cell that derives from human. Yue Liu, Yongqun He An immortal peripheral neuron cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生外周神经元细胞系细胞。 immortal pig-tailed macaque arm-derived fibroblast cell line cell An immortal arm-derived fibroblast cell line cell that derives from pig-tailed macaque. Yue Liu, Yongqun He immortal pig-tailed macaque thoracic aorta-derived smooth muscle cell line cell An immortal thoracic aorta-derived smooth muscle cell line cell that derives from pig-tailed macaque. Yue Liu, Yongqun He immortal mouse mesonephros-derived cell line cell An immortal mesonephros-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal Chinese hamster female gonad-derived cell line cell immortal Chinese hamster female gonad-derived cell line cell 永生的中国仓鼠雌性性腺衍生细胞系细胞 An immortal female gonad-derived cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He An immortal female gonad-derived cell line cell that derives from Chinese hamster. Yue Liu, Yongqun He 源自中国仓鼠的永生雌性性腺衍生细胞系细胞。 immortal human chorion-derived cell line cell An immortal chorion-derived cell line cell that derives from human. Yue Liu, Yongqun He immortal horse thoracic aorta-derived smooth muscle cell line cell An immortal thoracic aorta-derived smooth muscle cell line cell that derives from horse. Yue Liu, Yongqun He immortal mouse lymphoid follicle-derived cell line cell An immortal lymphoid follicle-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal Syrian golden hamster fetal membrane-derived cell line cell An immortal fetal membrane-derived cell line cell that derives from Syrian golden hamster. Yue Liu, Yongqun He immortal vervet monkey cell line cell immortal vervet monkey cell line cell 永生的黑长尾猴细胞系细胞 An immortal cell line cell that derives from vervet monkey. Yue Liu, Yongqun He An immortal cell line cell that derives from vervet monkey. Yue Liu, Yongqun He 源自黑长尾猴的永生细胞系细胞。 immortal vervet monkey kidney-derived cell line cell immortal vervet monkey kidney-derived cell line cell 永生的黑长尾猴肾衍生细胞系细胞 An immortal kidney-derived cell line cell that derives from vervet monkey. Yue Liu, Yongqun He An immortal kidney-derived cell line cell that derives from vervet monkey. Yue Liu, Yongqun He 源自黑长尾猴的永生肾衍生细胞系细胞。 immortal mouse mast cell line cell immortal mouse mast cell line cell 永生的小鼠肥大细胞系细胞 An immortal mast cell line cell that derives from mouse. Yue Liu, Yongqun He An immortal mast cell line cell that derives from mouse. Yue Liu, Yongqun He 源自小鼠的永生肥大细胞系细胞。 immortal mouse epithelial cell line cell An immortal epithelial cell line cell that derives from mouse. Yue Liu, Yongqun He immortal mouse mixed endoderm/mesoderm-derived structure-derived cell line cell An immortal mixed endoderm/mesoderm-derived structure-derived cell line cell that derives from mouse. Yue Liu, Yongqun He immortal mouse liver-derived cell line cell immortal mouse liver-derived cell line cell 永生的小鼠肝衍生细胞系细胞