]> Oliver He hPSCreg-CLO Edison Ong Stefanie Seltmann BFO OWL specification label BFO OWL specification label BFO OWL规范标签 BFO OWL规范标签 BFO OWL specification label Really of interest to developers only Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. BFO OWL规范标签 只对开发人员感兴趣 将本体中的实体关联到用于在代码中表示它的变量的名称，这些代码从lispy规范生成BFO OWL 文件。 BFO CLIF规范标签 BFO CLIF specification label BFO CLIF specification label BFO CLIF规范标签 Person:Alan Ruttenberg BFO CLIF specification label Person:Alan Ruttenberg Really of interest to developers only Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 BFO CLIF规范标签 只对开发人员感兴趣 将本体中的实体关联到用于在BFO2 CLIF规范中表示它的术语上。 Cell line LINCS ID 细胞系LINCS ID LINCS ID 细胞系LINCS ID An annotation property that represents an ID used in the NIH LINCS project. An annotation property that represents an LINCS ID of a cell line. Oliver He, Jiangan Xie, Jie Zheng 表示细胞系的LINCS ID的注释属性。 Oliver He, Jiangan Xie Oliver He, Jiangan Xie 编辑首选术语 editor preferred term 编辑首选标签 editor preferred label 编辑首选术语~编辑首选标签 editor preferred term~editor preferred label editor preferred label editor preferred term editor preferred term~editor preferred label 编辑首选术语 编辑首选标签 editor preferred term editor preferred label editor preferred term editor preferred term~editor preferred label GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) editor preferred label 对于一类或属性的简洁的、有意义的、与人类友好的名称由本体开发商首选。 （美国英语） 编辑首选术语 编辑首选标签 用法示例 example of usage example of usage 用法示例 A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold. GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober example example of usage 例子 用法示例 短语描述一个类的名字应该如何使用。也可包括其他类型有助于直接理解类的语义的例子，如广为人知的类的原型子类或实例。虽然高水平的术语必不可少，对于低级别术语的示例（例如，Affymetrix HU133阵列）不 has curation status 有管理状态 has curation status 有管理状态 OBI_0000281 PERSON:Alan Ruttenberg PERSON:Bill Bug PERSON:Melanie Courtot has curation status 有管理状态 definition textual definition textual definition 文本定义 definition definition textual definition 定义 定义 文本定义 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. definition GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. definition textual definition 2012-04-05: Barry Smith OBI的官方定义解释了一个类或属性的含义：'应该是亚里士多德式的，形式化和规范化的。可以用口语定义'是糟糕的。 您能解决这样的问题吗？ 解释关于类或属性的表达含义的必要和充分条件的陈述。 Alan Ruttenberg 您提出的定义是一个合理的备选，除非它很常见，没有给出必要和充分的条件。大多数情况下它们是必要的，偶尔是必要的，充分的或者仅仅仅充分的。它们通常使用不是自己定义的术语，因此它们实际上不能通过这些标准进行评估。 关于拟议定义的具体内容： 我们没有“含义”，或“表达”或“属性”的定义。对于在预期意义上的“参考”，我认为我们使用术语“指示”。对于'表达'，我认为我们和你的意思是符号，或标识符。对于“含义”，它不同于类和属性。对于类，我们希望文档能够让读者确定一个实体是否是该类的实例。对于属性，让我们的目标读者决定，给定一对潜在的关系，判断关系成立的断言正确与否。 “目标读者”部分表明我们也指定了我们期望的能够理解定义的人，并且概括了人类和计算机读者以包含文本和逻辑定义。 就我个人而言，我更愿意削弱对文档的定义，并指出什么是可取的。 我们还有一个悬而未决的问题，就是如何针对不同的受众定位不同的定义。临床读者阅读chebi需要来自受过化学训练的受众的不同类型的定义文档/定义，同样需要一个适合本体工作者的定义。 The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. textual definition OBI的官方定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 官方的定义，解释类或属性的含义。应该是亚里士多德式的，形式化和规范化的。 可以通过口语定义进行扩充。 定义 editor note editor note 编者注 editor note 编者注 1 IAO:0000116 IAO:0000116 editor_note editor_note editor_note editor_note true true uberon uberon An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. GROUP:OBI:<http://purl.obfoundry.org/obo/obi> IAO:0000116 IAO:0000116 PERSON:Daniel Schober editor note editor_note editor_note editor_note editor_note uberon uberon 管理者注释用于其编辑器。它可能不包含在本体的出版版本中，所以它应该不包含最终用户了解本体所需的信息。 编者注 编辑_注释 编辑_注释 term editor definition editor 术语编辑者 definition editor term editor 术语编辑者 20110707, MC: label update to term editor and definition modified accordingly. See http://code.google.com/p/information-artifact-ontology/issues/detail?id=115. 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115. GROUP:OBI:<http://purl.obolibrary.org/obo/obi> Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people PERSON:Daniel Schober definition editor term editor 20110707，MC：术语编辑和定义进行相应的修改。见http://code.google.com/p/information-artifact-ontology/issues/detail?id=115。 术语编辑者 输入文件中术语编辑者的名称。术语编辑者是有关术语的信息交汇点。术语编辑者可以是，但并不总是，定义的作者，这可能是由几个人完成 alternative term alternative term 替代术语 替代术语 An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent) GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober alternative term 一类或属性的替代名称，这意味着与所述首选名称同样的事物（语义上等价） 替代术语 definition source definition source 定义来源 定义来源 Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Daniel Schober definition source formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 定义来源 正式引用，例如在外部数据库中的标识符，用于表示/定义的属性源（S）。自由文本表示/为定义属性源（S）。实例：在2007年1月31日的作者姓名，URI，MeSH术语C04，PUBMEDID，维基uri 论OBO-讨论邮件-列表，请参阅http://bit.ly/hgm99w curator notes curator notes 管理者注释 curator note curator note curator notes 管理者注释 IAO:0000232 IAO:0000232 curator_notes curator_notes curator_notes curator_notes true true uberon uberon An administrative note of use for a curator but of no use for a user IAO:0000232 PERSON:Alan Ruttenberg curator note curator_notes curator_notes uberon 管理者_注释 管理者_注释 管理者注释 管理者注释对管理者有用对用户无用 引自 imported from imported from 引自 For external terms/classes, the ontology from which the term was imported GROUP:OBI:<http://purl.obolibrary.org/obo/obi> PERSON:Alan Ruttenberg PERSON:Melanie Courtot imported from 外部术语/类，术语引入的本体 引自 expand expression to expand expression to OBO foundry unique label 说明 elucidation elucidation 说明 Person:Barry Smith Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms elucidation person:Alan Ruttenberg 在最高级别的本体中的原始术语如BFO是对我们理解现实最基本，以至于无法以非循环的方式来定义它们的术语。对于这些，因此，我们只能提供说明，通过例子和公理进行补充 说明 具有相关联的公理（nl） has associated axiom(nl) has associated axiom(nl) 具有相关联的公理（nl） An axiom associated with a term expressed using natural language Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(nl) 与一个使用自然语言表达的术语相关的公理 具有相关联的公理（nl） 具有相关联的公理（fol） has associated axiom(fol) has associated axiom(fol) 具有相关联的公理（fol） An axiom expressed in first order logic using CLIF syntax Person:Alan Ruttenberg Person:Alan Ruttenberg has associated axiom(fol) 使用CLIF语法在第一逻辑进行表达的公理 具有相关联的公理（fol） symbol from nomenclature authority the symbol assigned by the nomenclature authority Oliver He, Yue Liu full name from nomenclature authority the full name assigned by the nomenclature authority Oliver He, Yue Liu NCBI GeneID Oliver He, Yue Liu A GeneID in the NCBI Gene database NCBI LocusTag Oliver He, Yue Liu the NCBI LocusTag name of a gene gene map location the map location of a gene Oliver He, Yue Liu modification date a date of content modification Oliver He, Yue Liu organism NCBITaxon ID The NCBITaxon ontology ID of an organism. Oliver He, Yue Liu chromosome ID of gene A chromosome ID where a gene is located. Oliver He type of gene Oliver He an annotation property that specifies the type of a gene nomenclature status an annotation property that specifies a nomenclature status Oliver He has GO association an annotation property that shows the GO information associated with a specific gene. Yongqun He has PubMed association Yongqun He An annotation property that represents a gene's association with PubMed publication(s). temporal interpretation temporal interpretation https://code.google.com/p/obo-relations/wiki/ROAndTime https://github.com/oborel/obo-relations/wiki/ROAndTime An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context. temporal interpretation external_definition external_definition 外部_定义 external_definition 外部_定义 An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000001 UBPROP:0000001 external_definition external_definition external_definition external_definition true true uberon uberon An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000001 external_definition external_definition uberon 外部_定义 外部_定义 对外部来源未修改的类的替代文本定义。这个定义可能被用来为新类推导出一个广义的定义。 这个注释的属性可以用从外部本体如IAO注解属性替换 axiom_lost_from_external_ontology axiom_lost_from_external_ontology axiom_lost_from_external_ontology 公理_丢失_自_外部_本体 公理_丢失_自_外部_本体 A textual description of an axiom loss in this ontology compared to an external ontology. A textual description of an axiom loss in this ontology compared to an external ontology. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000002 UBPROP:0000002 axiom_lost_from_external_ontology axiom_lost_from_external_ontology axiom_lost_from_external_ontology axiom_lost_from_external_ontology true true uberon uberon A textual description of an axiom loss in this ontology compared to an external ontology. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000002 axiom_lost_from_external_ontology axiom_lost_from_external_ontology uberon 与外部本体相比，本本体中的公理缺失的文本描述。 公理_丢失_自_外部_本体 公理_丢失_自_外部_本体 这个注释的属性可以用从外部本体如IAO注解属性替换 homology_notes homology_notes homology_notes 同源_注释 同源_注释 Notes on the homology status of this class. Notes on the homology status of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000003 UBPROP:0000003 homology_notes homology_notes homology_notes homology_notes true true uberon uberon Notes on the homology status of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000003 homology_notes homology_notes uberon 关于这个类的同源性状态的注释。 同源_注释 同源_注释 这个注释的属性可以用从外部本体如IAO注解属性替换 has_relational_adjective has_relational_adjective has_relational_adjective 有_关系_形容词 有_关系_形容词 UBPROP:0000007 UBPROP:0000007 Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. has_relational_adjective has_relational_adjective has_relational_adjective has_relational_adjective true true uberon uberon UBPROP:0000007 Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. has_relational_adjective has_relational_adjective uberon 有_关系的_形容词 有_关系的_形容词 用于将类连接到其标签的形容词形式。例如，具有标签“肠”的类可能具有关系形容词“肠的”。 taxon_notes taxon_notes taxon_notes 分类_注释 分类_注释 Notes on the how instances of this class vary across species. Notes on the how instances of this class vary across species. UBPROP:0000008 UBPROP:0000008 taxon_notes taxon_notes taxon_notes taxon_notes true true uberon uberon Notes on the how instances of this class vary across species. UBPROP:0000008 taxon_notes taxon_notes uberon 关于这个类的实例在不同物种间的差异的注释。 分类_注释 分类_注释 function_notes function_notes function_notes 功能_注释 功能_注释 Notes on the evolved function of instances of this class. Notes on the evolved function of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000009 UBPROP:0000009 function_notes function_notes function_notes function_notes true true uberon uberon Notes on the evolved function of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000009 function_notes function_notes uberon 关于这个类的实例的演变函数的注释。 功能_注释 功能_注释 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 development_notes 发育_注释 development_notes development_notes 发育_注释 Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 development_notes development_notes true uberon Notes on the ontogenic development of instances of this class. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000011 development_notes development_notes uberon 关于这个类的实例的个体发育的注释。 发育_注释 发育_注释 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 external_ontology_notes external_ontology_notes external_ontology_notes 外部_本体_注释 外部_本体_注释 Notes on how similar or equivalent classes are represented in other ontologies. Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 UBPROP:0000012 external_ontology_notes external_ontology_notes external_ontology_notes external_ontology_notes true true uberon uberon Notes on how similar or equivalent classes are represented in other ontologies. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000012 external_ontology_notes external_ontology_notes uberon 外部_本体_注释 外部_本体_注释 注意在其他本体中如何表示相似或等价的类。 这个注解属性可以用来自外部本体的注释属性（例如IAO）替换 terminology_notes Notes on how lexical conventions regarding this class, in particular any issues that may arise due to homonyny or synonymy. This annotation property may be replaced with an annotation property from an external ontology such as IAO UBPROP:0000013 terminology_notes terminology_notes true uberon has_rank has_rank A metadata relation between a class and its taxonomic rank (eg species, family) ncbi_taxonomy ncbi_taxonomy contributor Contributor Contributor Contributor 贡献者 contributor 贡献者 dc-contributor dc-contributor dc-contributor dc-contributor true true uberon uberon dc-contributor dc-contributor uberon An entity responsible for making contributions to the content of the resource. Examples of a Contributor include a person, an organisation, or a service. Typically, the name of a Contributor should be used to indicate the entity. 一个实体应该有助于 资源的内容 贡献者的例子包括一个人，一个 组织或者一个服务。 典型地， 一个贡献者的名字 应该用于指示这个实体. dc-贡献者 dc-贡献者 Creator Creator An entity primarily responsible for making the content of the resource. Examples of a Creator include a person, an organisation, or a service. Typically, the name of a Creator should be used to indicate the entity. Date Date A date associated with an event in the life cycle of the resource. Typically, Date will be associated with the creation or availability of the resource. Recommended best practice for encoding the date value is defined in a profile of ISO 8601 [W3CDTF] and follows the YYYY-MM-DD format. 描述 Description Description Description 描述 An account of the content of the resource. Description may include but is not limited to: an abstract, table of contents, reference to a graphical representation of content or a free-text account of the content. 描述应该包含但不限于一个摘要， 内容表格, 内容的图形表示 或内容的自由文本描述 资源内容的说明。 Format Format The physical or digital manifestation of the resource. Typically, Format may include the media-type or dimensions of the resource. Format may be used to determine the software, hardware or other equipment needed to display or operate the resource. Examples of dimensions include size and duration. Recommended best practice is to select a value from a controlled vocabulary (for example, the list of Internet Media Types [MIME] defining computer media formats). Source Source A reference to a resource from which the present resource is derived. The present resource may be derived from the Source resource in whole or in part. Recommended best practice is to reference the resource by means of a string or number conforming to a formal identification system. Subject and Keywords Subject and Keywords The topic of the content of the resource. Typically, a Subject will be expressed as keywords, key phrases or classification codes that describe a topic of the resource. Recommended best practice is to select a value from a controlled vocabulary or formal classification scheme. Title Title Typically, a Title will be a name by which the resource is formally known. A name given to the resource. created_by creation_date has_alternative_id 有_可替代的_id has_alternative_id has_alternative_id 有_可替代的_id has_broad_synonym has_broad_synonym has_broad_synonym 有_广义的_同义词 有_广义的_同义词 database_cross_reference 数据库_交叉_引用 database_cross_reference database_cross_reference 数据库_交叉_引用 has_exact_synonym has_exact_synonym has_exact_synonym 有_精确的_同义词 有_精确的_同义词 has_narrow_synonym has_narrow_synonym has_narrow_synonym 有_狭义的_同义词 有_狭义的_同义词 has_obo_namespace has_obo_namespace has_obo_namespace 有_obo_命名空间 有_obo_命名空间 disease_ontology has_related_synonym has_related_synonym 有_相关的_同义词 has_related_synonym 有_相关的_同义词 id in_subset 在_子集 in_subset in_subset 在_子集 shorthand shorthand shorthand 标签 label label label depicted_by depicted_by 由_描述 part of part_of part of part_of Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. http://www.obofoundry.org/ro/#OBO_REL:part_of Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. a core relation that holds between a part and its whole is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) part_of this day is part of this year (occurrent parthood) has part has part has_part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. a core relation that holds between a whole and its part has part has_part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) inheres in at all times realizes Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process realizes this disease course realizes this disease this investigation realizes this investigator role this shattering realizes this fragility to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) concretized by at some time occupies spatial region at some time has_quality has_quality http://www.ebi.ac.uk/efo/has_quality has spatial occupant at some time has disposition at all times part of continuant at some time has continuant part at some time part of continuant at all times that whole exists has continuant part at all times that part exists has disease Jie Zheng, Yongqun He, Yu Lin, Allen Xiang This is a shortcut relation. It is equivalent to: participates_in some 'disease couse' and realizes some disease a disease disposition has been realized by a bearer. is in cell line repository an object property that specifies a cell line repository for a specifc cell line. SS, YH, UV, SS is disease model for an object property that represents a relation between a cell line cell and a disease. Asiyah Yu Lin, Yongqun He This object property is largely equivalent to the previous term 'is model for' (http://www.ebi.ac.uk/cellline#is_model_for). derived from organism a 'cell line cell derives from' object property between an entity (e.g., cell line cell in CLO) and an organism where the cell line cell is derived from some cell from the organism. In CLO, this is a short cut relation that represents: 'derived from' some (cell and ('part of' some organism)) derived from anatomic part a 'derives from' object property between an entity (i.e., cell line cell in CLO) and an anatomic part from an organism where the cell line cell is derived from some cell in the anatomic part (e.g., tissue or organ). The anatomic part is typically defined by UBERON in CLO. in CLO, this is a short cut relation that represents: 'derived from' some (cell and ('part of' some 'anatomic part')) derived from cell derived from cell line is about 7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of "mentions" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered "about" are predications - "The only person who knows the answer is sitting beside me" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic. Smith, Ceusters, Ruttenberg, 2000 years of philosophy This document is about information artifacts and their representations is about is_about is a (currently) primitive relation that relates an information artifact to an entity. person:Alan Ruttenberg has_specified_input 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works. PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Coutot A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_input see is_input_of example_of_usage is_specified_input_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Alan Ruttenberg is_specified_input_of some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay has_specified_output PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Courtot A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. PERSON: Alan Ruttenberg has_specified_output is_specified_output_of PERSON:Bjoern Peters A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Alan Ruttenberg is_specified_output_of achieves_planned_objective achieves_planned_objective A cell sorting process achieves the objective specification 'material separation objective' BP, AR, PPPB branch PPPB branch derived This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process. achieves_planned_objective modified according to email thread from 1/23/09 in accordince with DT and PPPB branch has grain has grain PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349 has grain the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car. Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form PERSON: Alan Ruttenberg objective_achieved_by This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process. objective_achieved_by OBI OBI is genome of organism is gene of organism bearer of A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence bearer of bearer_of is bearer of this apple is bearer of this red color this vase is bearer of this fragility participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process participates in participates_in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation has participant Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. a relation between a process and a continuant, in which the continuant is somehow involved in the process has participant http://www.obofoundry.org/ro/#OBO_REL:has_participant has_participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) concretizes A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant). A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant. An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process). concretizes has_quality derives_from derives from derives_from This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'. a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives from derives_from this cell derives from this parent cell (cell division) this nucleus derives from this parent nucleus (nuclear division) derives into This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'. a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity derives into derives_into this parent cell derives into this cell (cell division) this parent nucleus derives into this nucleus (nuclear division) has plasma membrane part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. overlaps http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) x overlaps y if and only if there exists some z such that x has part z and z part of y develops_from develops from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y develops into capable of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. capable of part of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. developmentally preceded by Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p developmentally succeeded by Inverse of developmentally preceded by mereotopologically related to A mereological relationship or a topological relationship Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) functionally related to has developmental potential involving x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). has potential to develop into x has the potential to develop into y iff x develops into y or if x is capable of developing into y has potential to directly develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y causally related to This relation groups causal relations between material entities and causal relations between processes immediate transformation of direct_transformation_of immediately transforms from causal agent in A relationship between a material entity and a process where the material entity has some causal role that influences the process causal relation between material entity and a process A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. has causal agent Inverse of 'causal agent in' related via dependence to A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes. lacks_plasma_membrane_part lacks_plasma_membrane_part http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y) entity 实体 entity BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 实体 An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) Entity Entity Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf Julius Caesar Verdi’s Requiem 实体 entity entity the Second World War your body mass index BFO 2参考：在经验性总结分析的所有领域，我们遇到两种一般术语。首先是指共相或类型的一般术语：animaltuberculosissurgical proceduredisease其次，是用来指以下实例组的一般术语，这些实例组实例化一个给定共性但对应于该共相的任何子共相的扩展，因为没有实体的内在本质讨论因为他们-只有他们-被视为属于给定的群体。例子是：对斯德哥尔摩病人进行的周三手术过程中诊断出结核分枝杆菌而购买的动物，被确定为临床试验的候选人＃2056-555根据莱昂纳多·达·芬奇（Leonardo da Vinci）条款制定的656-PPV表格的签名人。这些术语代表所谓的“专业化'[81 一个实体是存在或已经存在或将存在的任何事物。 （BFO2公理标签参考：[001-001]） 你的身体质量指数 凯撒大帝 威尔第年代安魂曲 实体 实体不具有闭合公理，因为子类不一定丧失所有可能性。例如，Werner Ceusters的“现实的部分”包括4类，实体（当BFO构造它们时）、普遍性、配置和关系。这是一个开放性的问题，即在BFO中所解释的实体是否会在某个时候也包含这些其他的现实部分。参见，例如“如何完全追踪所有事物”在http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf 第二次世界大战 continuant 常体 Continuant (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] continuant (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. continuant continuant if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) 常体 常体 BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) BFO 2参考：持续实体是可以被分割的实体，只能沿着空间维度分割成部分，例如产生您的桌子的部分，我们称之为它的腿、顶部、指甲。 “我的桌子从窗户延伸到门口。它有空间部分，可以在空间切成两半。不过，就时间而言，一个事物是连续的。“[60，p。 240 一个在任何时候都存在的实体，它持续存在，在维持其特性的同时且没有暂时的部分。 一个常体是一个持续、持久或持续存在且同时保持其身份的实体。 （BFO2中的公理标签参考：[008-002]） 如果b是一个常体，并且如果对于某个t，c在t时刻具有_常体_部分b，则c是一个常体。 （BFO2公理标签参考：[126-001]） 如果b是一个常体，并且如果，对于某个t，c是在t时刻的b的常体_部分，则c是一个常体。 （BFO2公理标签参考：[009-002]） 如果b是物质实体，则在b存在期间有一些时间间隔（以下称为一维时间区域）。 （BFO2公理标签：[011-002]） 常体 常体不具有闭合公理，因为子类不一定丧失所有可能性。例如，在涉及引入一些Ceuster的实体的其他部分的扩展中，提出了普遍性是否是连续性的问题 occurrent 行体 (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] 行体 (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] An entity that has temporal parts and that happens, unfolds or develops through time. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region Occurrent Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) Occurrent Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. 行体 BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) occurrent occurrent BFO 2参考：不是时间或时空区域的每一个行体都是依赖于某个独立的且不是空间区域的常体 BFO 2参考：每个过程之间获得的s-依赖和它的参与者从某种意义上说，必要的时候，除非这些或那些参与者也存在，否则这个过程是不可能存在的。一个过程可能有一系列参与者在其展开的不同阶段。因此在足球比赛过程中的不同时间场上可能会有不同的球员;但整个游戏的过程依赖于所有这些玩家。这个过程的一些暂时的部分将只s-依赖_于一些玩家。 Simons使用不同的术语来表示发生在不同区域的行体关系：通过'spn [e]'表示给定occurrent e的时空位置。并称这个区域为跨度。我们可以说一个行体在它的跨度内，在任何一个较大的地区，覆盖了所有较小的地区。现在假设我们已经固定了一个参考框架，以便我们不仅可以谈及时空，而且可以谈及空间区域（地点）和时间区域（时间）。一个行体的（相对于一个参考框架）的延伸是它正好占据的空间，而它的拼写同样也是它正好占据的时间。我们写“spr [e]”和“spl [e]”。分别为e的延伸和拼写，省略框架的提及。 occurrent 一个行体是一个在时间上展开的实体，或者是一个实体的瞬时边界（例如一个起点或终点），或者是一个时空或时空区域，其中这样一个实体占据_时空_区域或占据_空间_区域的。 （BFO2公理标签参考：[077-002]） 具有时间部分且随时间发生、展开或发展的实体。 如果b是具有时间部分的实体，则b是一个行体实体。 （BFO2公理标签参考：[079-001]） 每一个行体都会占据_时空_区域一些时空区域。 （BFO2公理标签参考：[108-001]） 行体 行体并不具有闭合公理，因为子类不一定丧失所有可能性。一个例子是一个进程和另一个进程的进程边界的总和。 independent continuant 独立常体 IndependentContinuant (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] 独立常体(IndependentContinuant) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) IndependentContinuant ic a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) ic independent continuant the bottom right portion of a human torso the interior of your mouth b是一个独立常体= Def. b是一个常体，使得在t时刻不存在c，也不存在t，从而在t时刻b s-依赖_于c。 （BFO2公理标签参考：[017-002]） 一个分子 一个原子 一个心脏 一个有机体 一个空间区域 一个管弦乐队。 一把椅子 一条腿 人体躯干的右下部分 你的嘴巴内部 对于任何独立常体b和任何时刻t，都有一些空间区域r，使得b在t时刻位_于r处。 （BFO2公理标签参考：[134-001]） 对于在其生命周期中的每个时间区域内每个独立的常体b和时间t，在t期间存在s-依赖_于b的实体。 （BFO2公理标签参考：[018-002]） 常体是质量和可实现实体的载体，其中其他实体在其中并且本身不能在任何地方存在。 独立常体(Independent Continuant) spatial region true true (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] s-region BFO 2 Reference: Spatial regions do not participate in processes. Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. SpatialRegion (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) process 过程 (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] BFO:0000015 Process a process of cell-division, \ a beating of the heart a process of meiosis p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) process (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. process process the course of a disease the life of an organism your process of aging. 一个减数分裂的过程 一个生物体的生命 一个细胞分裂的过程，\一个跳动的心脏 过程 Process BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) a process of sleeping bfo the flight of a bird p是一个进程= Def. p是一个常体，其具有时间适当的部分且对于某个时间t，p s-依赖_于t时刻的一些物质实体。 （BFO2公理标签参考：[083-003]） 一只鸟的飞行 过程 BFO 2参考文献：相比在行体领域的情况，自然单位在独立常体领域的存在更普遍。因此这里没有对象的对等物。在BFO 1.0'过程'中充当了这样一个对等物。在BFO 2.0中，“过程”相当于“物质实体”的对等物。那些自然的-与工程设计相对比，这里的意思是：在现实领域中确实存在的故意执行-单位通常是寄生于常体侧存在的自然单位，或者它们本质上是允许的。因此，我们可以计算生命;我们可以算足球比赛;我们可以计算在实验或化学制造中进行的化学反应。我们不能计算如发生在昆虫交配行为中的过程。即使自然单位是可识别的，例如周期性过程的周期，例如跳动心脏或生物体的睡眠/觉醒周期，过程在讨论中形成一个没有我们发现的那种不连续性（时间间隔）的序列，在这种不连续性中，如台球或斑马鱼或行星被明确的空间差距分开。有机体的生命是过程单元，但是它们也是从其他先前的过程（如受精）中连续地展开，然后展开连续的一系列后期过程，例如死后衰变。过程界限的清晰例子几乎总是属于法定类型（午夜，手术室宣布的死亡时间或者死亡证明，战争状态的开始） 一个常体，其具有时间适当的部分且对于某个时间t，p s-依赖_于t时刻的一些物质实体。 一个睡眠的过程 你的老化过程。 疾病的过程 过程 disposition 倾向 Disposition (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] disposition (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] Disposition an atom of element X has the disposition to decay to an atom of element Y b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) 倾向 (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type [89 BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. certain people have a predisposition to colon cancer children are innately disposed to categorize objects in certain ways. disposition the cell wall is disposed to filter chemicals in endocitosis and exocitosis BFO 2参考：倾向存在于强度连续体中。只有一小部分触发事件才能实现较弱的倾向形式。这些形式出现在相当数量的类似案例中。 倾向 If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) disposition the cell wall is disposed to filter chemicals in endocytosis and exocytosis b是倾向方式：b是可实现的实体； b的持有人是一些物质实体； b是这样的，如果它不复存在，那么它的持有人发生了物理变化； b的实现发生在且因为这个持有者处于一些特殊的物理环境中；这种实现是由于持有者的物理构成而发生的。 （BFO2公理标签参考：[062-002]） 倾向 元素X的原子具有衰减到元素Y的原子的倾向 如果b是一个可实现的实体，那么对于存在b的所有t时刻，b s-依赖_于t时刻的一个物质实体。 （BFO2公理标签参考：[063-002]） 孩子天生就倾向于以特定的方式对物体进行分类。 某些人有结肠癌的倾向 细胞壁被设置为过滤内吞作用和胞吐作用中的化学物质 realizable entity 可实现实体 (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] 可实现实体(RealizableEntity) A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) RealizableEntity realizable (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] realizable realizable entity the role of being a doctor 你的生殖器官的功能 你的血液的凝结倾向 可实现的 (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] RealizableEntity To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of this boundary to delineate where Utah and Colorado meet 一个特定依赖性常体，在常体实体中存在，并且在每个实体或一组实体中都不会全部展现出来。可实现实体的展示或实现是在特定情况下发生的特定表现、功能或过程。 作为医生的角色 可实现实体 所有可实现依赖常体都有独立常体，这些独立常体不是空间区域作为承载。 （BFO2公理标签参考：[060-002]） 要说b是一个可实现实体，就是说b是一个特定依赖性常体，它存在于某些依赖常体中，这个连续体不是一个空间区域，而是一个在相关类型的过程中实现的类型实例。 （BFO2公理标签参考：[058-002]） 这个边界角色描绘了犹他州和科罗拉多州的交汇点 这块金属的导电倾向。 quality 性质 性质 (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) bfo quality (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] BFO:0000019 If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) Quality quality quality the ambient temperature of this portion of air the color of a tomato the mass of this piece of gold. 性质 Quality the length of the circumference of your waist the shape of your nose the shape of your nostril 你的腰围的长度 你的鼻子的形状 你的鼻孔的形状 如果一个实体在任何时候都存在一个性质，那么在它存在的每个时间它就是一个性质。 （BFO2公理标签参考：[105-001]） 性质 番茄的颜色 质量是一个特定依赖性常体，与角色和性格相反，不需要任何进一步的过程才能实现。 （BFO2公理标签参考：[055-001]） 这块黄金的质量。 这部分空气的环境温度 specifically dependent continuant 特定依赖性常体 (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) sdc (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] SpecificallyDependentContinuant 特定依赖性常体(SpecificallyDependentContinuant) Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. SpecificallyDependentContinuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. sdc specifically dependent continuant the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella b是一个关系特定依赖性常体 = Def. b是特定依赖性常体并且有n &gt;1个独立常体c1，... cn不是空间区域且是这样的，即对于全部1个 i&lt;j n，ci和cj没有共同的部分，对于每个1 i n，在b存在的过程中每个时间t，b s-依赖_于 ci（BFO2中的公理标号：[131-004]） b是一个特定依赖性常体 = Def. b是一个常体& 存在一些独立常体c，c不是一个空间区域且是这样的，在b的存在过程地每个时间t，b s-依赖_于c。 （BFO2公理标签参考：[050-003]） 一个在其他实体中存在或由其他实体承担的常体。 A的每个实例都需要一些特定的B实例，这些B实例必须始终相同。 交互特定依赖性常体：这个键的功能打开这个锁和这个锁的相互依赖的配置：被这个键打开 作为医生的角色 关系独立常体（对个载体）：约翰对玛丽的爱，约翰与这座雕像之间的所有关系，以及约翰与他的下属之间的权力关系。 具体而言，相关常体不具有闭合公理，因为子类不一定丧失所有可能性。我们不确定在这里会发生什么，但是会有如什么是承诺，义务等等的问题。 在它中心的一块四分熟烤菲力牛排的粉色 局部特定依赖性常体：这个番茄的性质 捕食者角色和猎物角色的相互依赖由两个生物体在给定的相互作用中扮演 特定依赖性常体 质子供体和受体在化学反应中的相互依赖[79 这个洞的形状。 这条鱼的腐烂倾向 这部分马苏里拉奶酪的气味 这颗心的功能：抽血 role 角色 Role role 角色 (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. 角色 John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. Role b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) role role the priest role the role of a boundary to demarcate two neighboring administrative territories the role of a building in serving as a military target the role of a stone in marking a property boundary the role of subject in a clinical trial the student role BFO 2参考：非刚性共相的一个主要例子涉及角色，及为相应的管理目的而开发的本体可以完全由这类实体的代表组成。因此，“教授”的定义如下，b为t时的教授实例=Def.有一些c，c为教授角色的实例 & 在t时刻，c存在_于b，表示非刚性共相，所以还要做“护士”、“学生”、“上校”、“纳税人”等等。 （这些术语在哲学术语中都是阶段排序的。）通过在定义中使用角色术语，我们可以为这些实体创建一个BFO一致性处理，而这些实体根据这个事实，即一个教授实例可能同时是工会成员，没有教授角色类型的实例也是（在任何时候）工会成员角色类型的实例（任何时候任何颜色类型的实例都是长度类型的实例）。如果就业岗位的本体应该根据上述模式的角色来定义，这就使得本体能够正确地处理这样一个事实，即个人在生命的某个阶段只实例化相应的共相-教授、中士、护士。 b是一个角色意味着：b是可实现实体 & b的存在是因为在某些特定的物理、社会或制度环境中存在一些单一的承载者，在这种环境下，承载者不必是“ b不是这样的，如果它不复存在，那么承载者的物理组成就会改变。 （BFO2公理标签参考：[061-001]） 一个可实现实体，它的表现会带来某种结果或结局，而这种结果或结局对于一个常体来说并不是必不可少的，因为它是一种事物，但它可以在某种自然的，社会的或制度的环境中，被这种常体所服务或参与。 作为军事目标的建筑物的角色 学生角色 患者在临床试验中的作用 牧师的角色 石头在标记一个属性边界中的角色 约翰对玛丽的丈夫角色依赖于玛丽对约翰的妻子角色，二者都依赖于由约翰和玛丽组成的对象集合，其中包括约翰和玛丽作为成员部分通过婚姻关系性质而成为一体。 角色 边界划分两个邻近的行政区域的角色 fiat object part 虚拟对象部分 BFO:0000024 bfo three-dimensional spatial region ThreeDimensionalSpatialRegion 3d-s-region (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) a cube-shaped region of space a sphere-shaped region of space, object 客体 BFO:0000030 bfo generically dependent continuant 普遍依赖性常体 gdc GenericallyDependentContinuant (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] 普遍依赖性常体(GenericallyDependentContinuant) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. GenericallyDependentContinuant The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) gdc generically dependent continuant the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. b是一个普遍依赖性常体 = Def. b是g-依赖_于一个或多个其他实体的常体。 （BFO2公理标签参考：[074-001]） 依赖于一个或另一个独立常体承载者的常体。对于A的每个实例都需要某个（一个独立常体类型）B的实例，但是B实例服务的对象可能会随时变化。 在您的笔记本电脑上的PDF文件，这个PDF文件是我的笔记本电脑上的副本 数据库中的条目是在硬盘驱动器中实例化为性质实例的模式。数据库本身就是这些模式的集合。在创建数据库时，您将创建普遍依赖性常体类型数据库的特定实例。数据库中的每个条目都是普遍依赖性常体类型IAO的一个实例：信息内容实体。 普遍依赖性常体 这个蛋白质分子的序列;在该蛋白质分子中是其序列的拷贝。 material entity 物质实体 (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] 物质实体(MaterialEntity) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 material BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. BFO:0000040 Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) MaterialEntity MaterialEntity a flame a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic bfo every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) material material entity the undetached arm of a human being BFO 2参考文献：“物质”旨在涵盖质量和能量（我们将在BFO的后续版本中介绍对部分能量的本体处理）。物质的一部分是任何包括基本粒子在内的适当或不适当的部分：夸克和轻子，包括电子，是迄今为止发现的最小的粒子；重子粒子在更高的粒度水平（包括质子和中子）；原子和分子的含量更高，形成由生物学家研究的细胞、器官、生物体和其他物质实体，由地质学家研究的岩石部分，由古生物学家研究的化石等等。物质实体是三维实体（在三个空间维度上扩展的实体），与它们参与的过程相反，它们是四维实体 （实体也沿着时间维度延伸）。根据FMA，物质实体可以有作为部分的非物质实体-包括下面标识为位置的实体；例如你的小肠的内部（或“腔”）是您身体的一部分。 BFO 2.0在这里体现了遵循FMA的决定。 BFO 2参考：对象，许可对象部分和对象聚合并是材料实体的细节。邀请用户提出物质实体的新子类别。 BFO 2参考：物质实体（常体）甚至可以在获得和丢失物质部分时保持其性质。常体与行体形成对比，后者在连续的时间部分或阶段展开自己[60] 一个人 一个人的无袖手臂 一个光子 一个海浪 一个物质实体是一个独立常体，它的某些部分是适当的或不适当的常体部分。 （BFO2公理标签参考：[019-002]） 一个独立常体，是空间扩展的，其性质独立于其他实体，可以通过时间来维持。 一个能量波 一场流行病 一阵烟雾 一阵龙卷风 人类的一个总和。 以一个物质实体作为常体部分的每个实体都是物质实体。 （BFO2公理标签参考：[020-002]） 森林大火 火焰 物质 物质实体 物质实体为常体部分的每个实体也是物质实体。 （BFO2公理标签参考：[021-002]） 飓风 immaterial entity 非物质实体 BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10 immaterial ImmaterialEntity anatomical structure 解剖结构 material anatomical entity 物质解剖实体 cell part 细胞部分 molecular entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. CHEBI:23367 chebi_ontology chemical entity chemical entity 化学实体 A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. CHEBI:24431 chebi_ontology chemical entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. CHEBI:24431 chebi_ontology chemical entity 化学实体 化学实体是对化学感兴趣的物理实体，包括分子实体、其部分及化学物质。 organic group Any substituent group or skeleton containing carbon. CHEBI:33247 chebi_ontology amino-acid residue CHEBI:33708 When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. amino acid residue chebi_ontology protein residue organic amino compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. CHEBI:50047 chebi_ontology cell line cell culturing cell line cell culturing 细胞系细胞培养 a maintaining cell culture process that keeps cell line cell alive and actively cultured. 维持细胞株存活和活跃培养的细胞培养过程。 YH YH a maintaining cell culture process that keeps cell line cell alive and actively cultured. cell line cell cell line cell 细胞系细胞 A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture cell line cell 一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分 Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters A 'cell line cell' is a part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures. A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture 一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分 A 'cell line cell' is a part of a cell line established through the passaging/selection of a primary cultured cells or the experimental modification of an existing cell line. New types of cell line cells are established after sufficient passaging of a primary culture to establish a stable and homogenous population that qualifies as a line (typically 1-20 passages), or following some spontaneous or experimental modification that confers novel characteristics to an existing line. A cell line cell typically has mutations of five or more genes compared to the original cell that derives the cell line cell. Some gene mutations may turn on some oncogenes. Cell line cells can be in active culture, stored in a quiescent state for future use (e.g. frozen in liquid nitrogen), or applied in experimental procedures. Yongqun He, Matthew Brush, Sirarat Sarntivijai, Alexander Diehl, Jie Zheng, Yu Lin, Bjoern Peters cell line cell “细胞系细胞”是通过原代培养细胞的传代/选择或现有细胞系的实验性修饰而建立的细胞系的一部分。新类型的细胞系细胞的建立过程是原代培养物充分传代后以建立符合条件（典型地1-20代）的稳定且同质的群体，或者在某些自发或实验性修饰之后赋予现有细胞系新的特征。与产生细胞系细胞的原始细胞相比，细胞系细胞通常具有5个或更多个基因的突变。 一些基因突变可能会开启一些致癌基因。 细胞系细胞可处于活性培养物中，以静止状态储存以供将来使用（例如在液氮中冷冻），或者在实验程序使用。 细胞系细胞 adherent cell line culturing adherent cell line culturing 贴壁细胞系培养 adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation. adherent cell line culturing is a cell line culturing method where cells require a surface for growth and differentiation. 贴壁细胞系培养是一种细胞系培养方法，其中细胞需要一个表面进行生长和分化。 cell line repository role cell line repository role 细胞库角色 SS, YH a role that inheres in a cell line repository organization. 一个细胞系资源组织中所起的作用 SS, YH a role that inheres in a cell line repository organization. cell line repository cell line repository 细胞库 一个作为细胞系存储库的组织。 SS, YH SS, YH an organization that serves as a repository of cell lines. an organization that serves as a repository of cell lines. immortal cell line cell immortal cell line cell 永生细胞系细胞 immortal cell line cell permanent cell line cell A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line. Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak continuous cell line cell 连续细胞系细胞 A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line. 预期能够进行无限次分裂的细胞系细胞，作为永生细胞系一部分，能够支持体外无限增殖。 永久细胞系细胞 Yongqun He, Matthew Brush, Allen Xiang, Asiyah Yu Lin, Sirarat Sarntivijai, James Malone, Jie Zheng, Tomasz Adamusiak continuous cell line cell immortal cell line cell permanent cell line cell 永生细胞系细胞 adherent cell culture growth mode adherent cell culture growth mode 贴壁细胞培养生长模式 一种细胞培养生长模式：细胞需要粘附在细胞培养板上生长 YH YH a cell culture growth mode that indicates a cell needs to adhere to a cell culture plate to grow. a cell culture growth mode that indicates a cell needs to adhere to a cell culture plate to grow. cell culture growth mode cell culture growth mode 细胞培养生长模式 YH a disposition that represents a mode of cell culture growth, i.e., the cell will grow at a specific cell culture mode. For example, an adherent cell culture growh mode means that the cell will grow when the cell is adhere to a cell culture plate. YH a disposition that represents a mode of cell culture growth, i.e., the cell will grow at a specific cell culture mode. For example, an adherent cell culture growh mode means that the cell will grow when the cell is adhere to a cell culture plate. 一种代表细胞培养生长模式的配置，即细胞将以特定细胞培养模式生长。 例如，贴壁细胞培养生长模式意味着当细胞粘附于细胞培养板时细胞将生长。 cell line 细胞系 A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene". Note that common usage in the literature is often of the form "a human colorectal cancer cell line", as seen above. But such references to studies in "a line" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'. In the spring of 2013, a working group comprised of domain experts and representatives from CLO, OBI, CL, and ReO worked to establish a consensus model and definitions of cultured cells across these efforts. This included a careful characterization of how the term 'cell line' should be defined and applied. Notes about this work and its outcomes can be found on the CLO wiki here: http://code.google.com/p/clo-ontology/wiki/Cell_Lines The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, ‘lines’ are capable of being characterized and stably propagated over a period of time. A new *type* of cell line can be established not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.). The definition provided here establishes the 'scale' of cell populations that qualify as cell lines - specifically those with a shared propagation history in culture. In this way, the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.  As defined here, 'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quiescent state for future use. 当培养物经过有意的实验过程以建立更均匀和稳定的细胞群时（参见“建立细胞系”），使用术语“系”。这将需要一个或多次传代，但可能涉及额外的选择过程。通过这样的传代和/或选择过程，产生的'细胞系'达到一定水平的遗传稳定性和组成均一性，这在原代培养物中通常是不存在的。由于它们的相对同质性，“细胞系”能够在一段时间内被表征和稳定地增殖。一种新*型*细胞系不仅可以通过原代培养物的传代/选择建立，而且可以通过对现有系列的实验性修饰（例如永生化，稳定的遗传修饰，用于抗性子集的药物选择等）来建立。 这里提供的定义确立了符合细胞系特征的细胞群的“范围” - 特别是那些在培养中具有共同繁殖历史的细胞群。通过这种方式，“细胞系”类划分代表研究人员在科学实践中实际使用的细胞群 - 例如作为培养、实验和分享的投入。定义是这样的，细胞系将显示重要的属性。例如，它们将具有相对均匀的细胞类型组成，因为它们的连续共增殖而经历了类似的选择压力。此外，这些细胞群还可以通过传代数来表征，这也是由于它们共同的传代史。如此处所定义的，“细胞系”可以指活性培养物中，实验性应用的或以静止状态存储以备将来使用的细胞群。 He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene". Note that common usage in the literature is often of the form "a human colorectal cancer cell line", as seen above. But such references to studies in "a line" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'. A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). In the spring of 2013, a working group comprised of domain experts and representatives from CLO, OBI, CL, and ReO worked to establish a consensus model and definitions of cultured cells across these efforts. This included a careful characterization of how the term 'cell line' should be defined and applied. Notes about this work and its outcomes can be found on the CLO wiki here: http://code.google.com/p/clo-ontology/wiki/Cell_Lines MB, SS, JZ, MAH, BP, CS, YH MB, SS, JZ, MAH, BP, CS, YH 在2013年春季，由CLO，OBI，CL和ReO的领域专家和代表组成的工作组经过这些努力中建立了共识模型和培养细胞的定义。 这包括仔细描述术语“细胞系”应该如何定义和应用。 关于这项工作及其结果的说明可以在CLO wiki上找到： http://code.google.com/p/clo-ontology/wiki/Cell_Lines The term 'line' is used when a culture has undergone an intentional experimental process to establish a more uniform and stable population of cells (see 'establishing cell line'). This will require one or more passages, but may involve additional selection processes. Through such passaging and/or selection processes, the resulting 'line' attains some level of genetic stability and compositional homogeneity which is typically absent in primary cultures. Because of their relative homogeneity, ‘lines’ are capable of being characterized and stably propagated over a period of time. A new *type* of cell line can be established not only through the passaging/selection of a primary culture, but also through experimental modifications of existing lines (e.g. immortalization, stable genetic modifications, drug selection for a resistant subset, etc.). The definition provided here establishes the 'scale' of cell populations that qualify as cell lines - specifically those with a shared propagation history in culture. In this way, the 'cell line' class demarcates populations that represent what researchers actually use in the practice of science - e.g. as inputs to culturing, experimentation, and sharing. The definition is such that cell lines will exhibit important attributes. For example, they will have a relatively homogenous cell type composition as they have experienced similar selective pressures due to their continuous co-propagation. In addition, these populations can also be characterized by a passage number, again owing to their common passaging history.  As defined here, 'cell line' can refer to a population of cells in active culture, applied experimentally, or stored in a quiescent state for future use. 一个培养细胞群体，其代表具有共同增殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。 培养的细胞群体代表具有共同繁殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。 He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.: "为了评估APC的转录效应，我们研究了含有锌诱导型APC基因的人结直肠癌细胞系（HT29-APC）和含有类似诱导型lacZ基因的对照细胞系（HT29-β-Gal）". 请注意，文献中的常见用法通常是“人类结直肠癌细胞系”的形式",如上所见。 但是对"一个细胞系"研究的这种引用，指的是输入培养或实验的离散细胞群体，而不是整个细胞系。 我们将这些离散的群体称为'细胞系'。 cell line 细胞系 immortal eukaryotic cell line cell immortal eukaryotic cell line cell 永生的真核细胞系细胞 ZX, YH a immortal cell line cell that is derived from eukaryotic cell ZX, YH a immortal cell line cell that is derived from eukaryotic cell 源自真核细胞的永生细胞系细胞 immortal animal cell line cell immortal animal cell line cell 永生的动物细胞系细胞 ZX, YH a immortal eukaryotic cell line that is derived from animal cell immortal animal cell line ZX, YH a immortal eukaryotic cell line that is derived from animal cell immortal animal cell line 永生的动物细胞系 源自动物细胞的永生真核细胞系 immortal connective tissue cell line cell immortal connective tissue cell line cell 永生的结缔组织细胞系细胞 ZX, YH a immortal animal cell line that is derived from connective tissue cell ZX, YH a immortal animal cell line that is derived from connective tissue cell 源自结缔组织细胞的永生动物细胞系 immortal fibroblast cell line cell immortal fibroblast cell line cell 永生的成纤维细胞系细胞 ZX, YH a immortal connective tissue cell line that is derived from fibroblast immortal fibroblast cell line ZX, YH a immortal connective tissue cell line that is derived from fibroblast immortal fibroblast cell line 永生的成纤维细胞系 源自成纤维细胞的永生结缔组织细胞系 immortal somatic cell line cell immortal somatic cell line cell 永生的体细胞系细胞 ZX, YH a cell line that is derived from somatic cell ZX, YH a cell line that is derived from somatic cell 源自体细胞的细胞系 immortal arm-derived fibroblast cell line cell An immortal fibroblast cell line cell that derives from arm. Yue Liu, Yongqun He immortal human arm-derived fibroblast cell line cell An immortal arm-derived fibroblast cell line cell that derives from human. Yue Liu, Yongqun He immortal human fibroblast cell line cell immortal human fibroblast cell line cell 永生的人成纤维细胞系细胞 An immortal fibroblast cell line cell that derives from human. Yue Liu, Yongqun He An immortal fibroblast cell line cell that derives from human. Yue Liu, Yongqun He 源自人的永生成纤维细胞系细胞。 CCD-1112Sk cell ATCC: CRL-2429 https://www.atcc.org/products/all/CRL-2429 CCD-1112Sk AG07645 cell ALZHEIMER DISEASE, FAMILIAL, TYPE 3 AG07645 Chao Pang OMIM: 607822 stem cell line cell While stem cells hold great promise for biomedical research, the in vitro propagation and maintenance of these cells in an undifferentiated state is essential. Reference: https://www.atcc.org/~/media/7E031EF950594BC3B85A411AE1DC9684.ashx A cell line cell that is cultured in vitro and possesses two capabilities: (1) it can self-renew, which means that it can divide indefinitely while remaining in an undifferentiated state; and (2) it is pluripotent or multipotent, which means that it can differentiate to form a specialized cell type. WEB: https://en.wikipedia.org/wiki/Stem-cell_line Yongqun He, Sirarat Sarntivijai, Alexander Diehl embryonic stem cell line cell A stem cell line cell that is dervied from an embryotic stem cell, a pluripotent stem cell derived from the inner cell mass of a blastocyst, an early-stage perimplantation embryo. YH, AD ES cell line cell https://en.wikipedia.org/wiki/Embryonic_stem_cell human embryonic stem cell line cell https://en.wikipedia.org/wiki/Embryonic_stem_cell YH, AD hES cell line cell An embryonic stem cell line cell that is dervied from a cell in human embryo. hESC line cell hESC Line H1 cell A human ES cell line cell that expresses cell surface markers specific to undifferentiated nonhuman primate ES and human EC cells: : stage-specific embryonic antigen (SSEA)–3, SSEA-4, TRA-l-60, TRA-1- 81, and alkaline phosphatase. It has a normal 46, XY karyotype, O+ blood type. Teratomas are formed upon cell injection into SCID mice. These teratomas include cells from all three germ layers. H1-hESC YH, AD https://discovery.lifemapsc.com/stem-cell-differentiation/in-vitro-cells/inner-cell-mass-homo-sapiens-line-h1-wa01-wicell-research-institute-inc induced pluripotent stem cell line cell https://en.wikipedia.org/wiki/Embryonic_stem_cell YH, AD A stem cell line cell that is pluripotent and is generated from an adult somatic cell. https://www.ncbi.nlm.nih.gov/pubmed/16904174 iPS cell https://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell iPSC human induced pluripotent stem cell line cell human iPS cell line cell hiPSC YH, AD, SS An induced pluripotent stem cell line cell that is derived from a human cell. H9 ES cell https://discovery.lifemapsc.com/stem-cell-differentiation/in-vitro-cells/inner-cell-mass-homo-sapiens-line-h9-wa09-wicell-research-institute-inc LES-1001 http://lincsportal.ccs.miami.edu/cells/#/view/LES-1001 LINCS team, YH This human ES cell line expresses cell surface markers specific to undifferentiated nonhuman primate ES and human EC cells: stage-specific embryonic antigen (SSEA)–3, SSEA-4, TRA-l-60, TRA-1- 81, and alkaline phosphatase. It has a normal 46, XX karyotype. Teratomas are formed upon cell injection into SCID mice. These teratomas include cells from all three germ layers. human fibroblast-induced pluripotent stem cell line cell human fibroblast-iPS cell line cell YH, SS forskin fibroblast-derived hiPSC SS, YH human forskin fibroblast-induced pluripotent stem cell line cell BIHi001-A cell https://hpscreg.eu/cell-line/BIHi001-A Cellosaurus:CVCL_IT54 Stefanie Seltmann, Oliver He BCRT#1 BCRT-3 BioSamples:SAMEA103885931 tissue donor An organism that provides/donotes a tissue to be used for a biomedical study or a clinical application. Stefanie Seltmann, Oliver He human tissue donor A human thoat donotes tissue Stefanie Seltmann, Oliver He EDi008-B G51D-4 EDIi008-B Cellosaurus: CVCL_LE56 https://www.ncbi.nlm.nih.gov/pubmed/23404372 BioSamples: SAMEA3174606 EDINi008-B https://hpscreg.eu/cell-line/EDi008-B Stefanie Seltmann, Oliver He ECACC: 66540061 EBiSC: EDi008-B AAUe001-A Stefanie Seltmann, Yongqun He AAUe002-A Stefanie Seltmann, Yongqun He AAUe003-A Stefanie Seltmann, Yongqun He AAUe004-A Stefanie Seltmann, Yongqun He ACTe001-A Stefanie Seltmann, Yongqun He ACTe002-A Stefanie Seltmann, Yongqun He ACTe003-A Stefanie Seltmann, Yongqun He AXORe001-A Stefanie Seltmann, Yongqun He AXORe002-A Stefanie Seltmann, Yongqun He AXORe004-A Stefanie Seltmann, Yongqun He AXORe005-A Stefanie Seltmann, Yongqun He AXORe007-A Stefanie Seltmann, Yongqun He BCHe001-A Stefanie Seltmann, Yongqun He BCHe002-A Stefanie Seltmann, Yongqun He BCHe003-A Stefanie Seltmann, Yongqun He BCHe004-A Stefanie Seltmann, Yongqun He BCHe005-A Stefanie Seltmann, Yongqun He BCHe006-A Stefanie Seltmann, Yongqun He BCRTi001-A Stefanie Seltmann, Yongqun He BCRTi002-A Stefanie Seltmann, Yongqun He BCRTi004-A Stefanie Seltmann, Yongqun He BCRTi005-A Stefanie Seltmann, Yongqun He BIHi002-A Stefanie Seltmann, Yongqun He BIHi004-A Stefanie Seltmann, Yongqun He BIHi005-A Stefanie Seltmann, Yongqun He BIHi006-D Stefanie Seltmann, Yongqun He BIHi007-A Stefanie Seltmann, Yongqun He BIHi008-A Stefanie Seltmann, Yongqun He BIHi009-A Stefanie Seltmann, Yongqun He BIHi010-A Stefanie Seltmann, Yongqun He BIHi011-A Stefanie Seltmann, Yongqun He BIHi012-A Stefanie Seltmann, Yongqun He BIHi015-A Stefanie Seltmann, Yongqun He BIHi016-A Stefanie Seltmann, Yongqun He BIHi017-A Stefanie Seltmann, Yongqun He BIHi018-A Stefanie Seltmann, Yongqun He BIHi019-A Stefanie Seltmann, Yongqun He BIHi024-A Stefanie Seltmann, Yongqun He BIHi025-A Stefanie Seltmann, Yongqun He BIHi028-B Stefanie Seltmann, Yongqun He BIHi029-A Stefanie Seltmann, Yongqun He BIHi030-C Stefanie Seltmann, Yongqun He BIHi031-B Stefanie Seltmann, Yongqun He BIHi038-B Stefanie Seltmann, Yongqun He BIONi010-A Stefanie Seltmann, Yongqun He BIONi010-B Stefanie Seltmann, Yongqun He BIONi010-C Stefanie Seltmann, Yongqun He BIONi013-A Stefanie Seltmann, Yongqun He BIONi014-A Stefanie Seltmann, Yongqun He BIONi015-A Stefanie Seltmann, Yongqun He BIONi016-A Stefanie Seltmann, Yongqun He BIONi017-A Stefanie Seltmann, Yongqun He BIONi018-A Stefanie Seltmann, Yongqun He BIONi019-A Stefanie Seltmann, Yongqun He BIONi020-A Stefanie Seltmann, Yongqun He BIONi021-A Stefanie Seltmann, Yongqun He BIONi022-A Stefanie Seltmann, Yongqun He BIONi023-A Stefanie Seltmann, Yongqun He BIONi024-A Stefanie Seltmann, Yongqun He BIONi025-A Stefanie Seltmann, Yongqun He BIONi026-A Stefanie Seltmann, Yongqun He BIONi027-A Stefanie Seltmann, Yongqun He BIONi028-A Stefanie Seltmann, Yongqun He BIONi029-A Stefanie Seltmann, Yongqun He BIONi030-A Stefanie Seltmann, Yongqun He BIONi031-A Stefanie Seltmann, Yongqun He BIONi032-A Stefanie Seltmann, Yongqun He BIONi033-A Stefanie Seltmann, Yongqun He BIONi034-A Stefanie Seltmann, Yongqun He BIONi035-A Stefanie Seltmann, Yongqun He BIONi037-A Stefanie Seltmann, Yongqun He BIOTi001-A Stefanie Seltmann, Yongqun He BJMUe001-A Stefanie Seltmann, Yongqun He BJMUe002-A Stefanie Seltmann, Yongqun He BJMUe003-A Stefanie Seltmann, Yongqun He BJMUe004-A Stefanie Seltmann, Yongqun He CAMe001-A Stefanie Seltmann, Yongqun He CAMe002-A Stefanie Seltmann, Yongqun He CAMi001-A Stefanie Seltmann, Yongqun He CAMi002-A Stefanie Seltmann, Yongqun He CAMi002-B Stefanie Seltmann, Yongqun He CAMi002-C Stefanie Seltmann, Yongqun He CAMi004-A Stefanie Seltmann, Yongqun He CAMi005-A Stefanie Seltmann, Yongqun He CAMi005-B Stefanie Seltmann, Yongqun He CBi001-A Stefanie Seltmann, Yongqun He CBi002-A Stefanie Seltmann, Yongqun He CDIi001-A Stefanie Seltmann, Yongqun He CDIi004-A Stefanie Seltmann, Yongqun He CEBe001-A Stefanie Seltmann, Yongqun He CEBe002-A Stefanie Seltmann, Yongqun He CEBe006-A Stefanie Seltmann, Yongqun He CEBe007-A Stefanie Seltmann, Yongqun He CEBe008-A Stefanie Seltmann, Yongqun He CEBe009-A Stefanie Seltmann, Yongqun He CEBe010-A Stefanie Seltmann, Yongqun He CEBe011-A Stefanie Seltmann, Yongqun He CEBe012-A Stefanie Seltmann, Yongqun He CEBe013-A Stefanie Seltmann, Yongqun He CEBe014-A Stefanie Seltmann, Yongqun He CEBe015-A Stefanie Seltmann, Yongqun He CEBe016-A Stefanie Seltmann, Yongqun He CEBe017-A Stefanie Seltmann, Yongqun He CEBe018-A Stefanie Seltmann, Yongqun He CEBe019-A Stefanie Seltmann, Yongqun He CEBe020-A Stefanie Seltmann, Yongqun He CEBe021-A Stefanie Seltmann, Yongqun He CEBe022-A Stefanie Seltmann, Yongqun He CEBe023-A Stefanie Seltmann, Yongqun He CEBe024-A Stefanie Seltmann, Yongqun He CEBe025-A Stefanie Seltmann, Yongqun He CEBe026-A Stefanie Seltmann, Yongqun He CEBe027-A Stefanie Seltmann, Yongqun He CEBe028-A Stefanie Seltmann, Yongqun He CEBe029-A Stefanie Seltmann, Yongqun He CEBe030-A Stefanie Seltmann, Yongqun He CEBe031-A Stefanie Seltmann, Yongqun He CEBe032-A Stefanie Seltmann, Yongqun He CEBe033-A Stefanie Seltmann, Yongqun He CEBe034-A Stefanie Seltmann, Yongqun He CEBe035-A Stefanie Seltmann, Yongqun He CENSOi001-B Stefanie Seltmann, Yongqun He CENSOi002-B Stefanie Seltmann, Yongqun He CENSOi003-B Stefanie Seltmann, Yongqun He CENSOi005-A Stefanie Seltmann, Yongqun He CENSOi007-A Stefanie Seltmann, Yongqun He CENSOi008-A Stefanie Seltmann, Yongqun He CHAe001-A Stefanie Seltmann, Yongqun He CHAe002-A Stefanie Seltmann, Yongqun He CHULAe001-A Stefanie Seltmann, Yongqun He CHUQi001-A Stefanie Seltmann, Yongqun He CIMHi001-A Stefanie Seltmann, Yongqun He CIMHi002-A Stefanie Seltmann, Yongqun He CIMHi003-A Stefanie Seltmann, Yongqun He CMFTe001-A Stefanie Seltmann, Yongqun He CMFTe002-A Stefanie Seltmann, Yongqun He CMFTe003-A Stefanie Seltmann, Yongqun He CMFTe004-A Stefanie Seltmann, Yongqun He CRMi001-A Stefanie Seltmann, Yongqun He CRMi003-A Stefanie Seltmann, Yongqun He CRMi004-A Stefanie Seltmann, Yongqun He CRMi005-A Stefanie Seltmann, Yongqun He CRTDi001-A Stefanie Seltmann, Yongqun He CSSi001-A Stefanie Seltmann, Yongqun He CSSi002-A Stefanie Seltmann, Yongqun He CSSi003-A Stefanie Seltmann, Yongqun He CSSi004-A Stefanie Seltmann, Yongqun He CSSi005-A Stefanie Seltmann, Yongqun He CSSi006-A Stefanie Seltmann, Yongqun He CSSi007-A Stefanie Seltmann, Yongqun He CSUe001-A Stefanie Seltmann, Yongqun He CSUe004-A Stefanie Seltmann, Yongqun He CSUe005-A Stefanie Seltmann, Yongqun He CUBi001-A Stefanie Seltmann, Yongqun He CUBi002-B Stefanie Seltmann, Yongqun He DALCe001-A Stefanie Seltmann, Yongqun He DANi001-C Stefanie Seltmann, Yongqun He EDe001-A Stefanie Seltmann, Yongqun He EDe002-A Stefanie Seltmann, Yongqun He EDe003-A Stefanie Seltmann, Yongqun He EDe004-A Stefanie Seltmann, Yongqun He EDe005-A Stefanie Seltmann, Yongqun He EDe006-A Stefanie Seltmann, Yongqun He EDe008-A Stefanie Seltmann, Yongqun He EDe009-A Stefanie Seltmann, Yongqun He 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Stefanie Seltmann, Yongqun He ESe018-A Stefanie Seltmann, Yongqun He ESe019-A Stefanie Seltmann, Yongqun He ESe020-A Stefanie Seltmann, Yongqun He ESe021-A Stefanie Seltmann, Yongqun He ESe022-A Stefanie Seltmann, Yongqun He ESe023-A Stefanie Seltmann, Yongqun He ESe024-A Stefanie Seltmann, Yongqun He ESe025-A Stefanie Seltmann, Yongqun He ESe026-A Stefanie Seltmann, Yongqun He ESe027-A Stefanie Seltmann, Yongqun He ESe028-A Stefanie Seltmann, Yongqun He ESe029-A Stefanie Seltmann, Yongqun He ESi001-A Stefanie Seltmann, Yongqun He ESi002-A Stefanie Seltmann, Yongqun He ESi003-A Stefanie Seltmann, Yongqun He ESi004-A Stefanie Seltmann, Yongqun He ESi005-A Stefanie Seltmann, Yongqun He ESi005-B Stefanie Seltmann, Yongqun He ESi006-A Stefanie Seltmann, Yongqun He ESi007-A Stefanie Seltmann, Yongqun He ESi008-A Stefanie Seltmann, Yongqun He ESi008-B Stefanie Seltmann, Yongqun He ESi028-A Stefanie Seltmann, Yongqun He ESi030-A Stefanie Seltmann, Yongqun He ESi031-A Stefanie Seltmann, Yongqun He ESi031-B Stefanie Seltmann, Yongqun He ESi031-C Stefanie Seltmann, Yongqun He ESi031-D Stefanie Seltmann, Yongqun He ESi032-A Stefanie Seltmann, Yongqun He ESi033-A Stefanie Seltmann, Yongqun He ESi034-A Stefanie Seltmann, Yongqun He ESi034-B Stefanie Seltmann, Yongqun He ESi035-A Stefanie Seltmann, Yongqun He ESi036-A Stefanie Seltmann, Yongqun He ESi037-A Stefanie Seltmann, Yongqun He ESi038-A Stefanie Seltmann, Yongqun He ESi038-B Stefanie Seltmann, Yongqun He ESi038-C Stefanie Seltmann, Yongqun He ESi040-A Stefanie Seltmann, Yongqun He ESi041-A Stefanie Seltmann, Yongqun He ESi041-B Stefanie Seltmann, Yongqun He ESi041-C Stefanie Seltmann, Yongqun He ESi042-A Stefanie Seltmann, Yongqun He ESi043-A Stefanie Seltmann, Yongqun He ESi044-A Stefanie Seltmann, Yongqun He ESi044-B Stefanie Seltmann, Yongqun He ESi044-C Stefanie Seltmann, Yongqun He ESi044-D Stefanie Seltmann, Yongqun He ESi045-A Stefanie Seltmann, Yongqun He ESi045-B Stefanie Seltmann, Yongqun He ESi045-C Stefanie Seltmann, Yongqun He ESi045-D Stefanie Seltmann, Yongqun He ESi046-A Stefanie Seltmann, Yongqun He ESi048-A Stefanie Seltmann, Yongqun He ESi049-A Stefanie Seltmann, Yongqun He ESi050-A Stefanie Seltmann, Yongqun He ESi051-A Stefanie Seltmann, Yongqun He ESi052-A Stefanie Seltmann, Yongqun He ESi053-A Stefanie Seltmann, Yongqun He ESi054-A Stefanie Seltmann, Yongqun He ESi055-A Stefanie Seltmann, Yongqun He ESi056-A Stefanie Seltmann, Yongqun He ESi057-A Stefanie Seltmann, Yongqun He ESi057-B Stefanie Seltmann, Yongqun He ESi058-A Stefanie Seltmann, Yongqun He ESi058-B Stefanie Seltmann, Yongqun He ESi059-A Stefanie Seltmann, Yongqun He ESi059-B Stefanie Seltmann, Yongqun He ESi060-A Stefanie Seltmann, Yongqun He ESi060-B Stefanie Seltmann, Yongqun He ESi065-A Stefanie Seltmann, Yongqun He ESIBIe001-A Stefanie Seltmann, Yongqun He ESIBIe002-A Stefanie Seltmann, Yongqun He ESIBIe003-A Stefanie Seltmann, Yongqun He ESIBIe004-A Stefanie Seltmann, Yongqun He ESIBIe005-A Stefanie Seltmann, Yongqun He ESIBIe006-A Stefanie Seltmann, Yongqun He EVMSe001-A Stefanie Seltmann, Yongqun He EVMSe002-A Stefanie Seltmann, Yongqun He EVMSe003-A Stefanie Seltmann, Yongqun He FAMRCi001-A Stefanie Seltmann, Yongqun He FAMRCi001-B Stefanie Seltmann, Yongqun He FAMRCi002-A Stefanie Seltmann, Yongqun He FAMRCi003-A Stefanie Seltmann, Yongqun He FAMRCi003-B Stefanie Seltmann, Yongqun He GENEAe001-A Stefanie Seltmann, Yongqun He GENEAe002-A Stefanie Seltmann, Yongqun He GENEAe003-A Stefanie Seltmann, Yongqun He GENEAe004-A Stefanie Seltmann, Yongqun He GENEAe005-A Stefanie Seltmann, Yongqun He GENEAe006-A Stefanie Seltmann, Yongqun He GENEAe007-A Stefanie Seltmann, Yongqun He GENEAe008-A Stefanie Seltmann, Yongqun He GENEAe009-A Stefanie Seltmann, Yongqun He GENEAe010-A Stefanie Seltmann, Yongqun He GENEAe011-A Stefanie Seltmann, Yongqun He GENEAe012-A Stefanie Seltmann, Yongqun He GENEAe013-A Stefanie Seltmann, Yongqun He GENEAe014-A Stefanie Seltmann, Yongqun He GENEAe015-A Stefanie Seltmann, Yongqun He GENEAe016-A Stefanie Seltmann, Yongqun He GENEAe017-A Stefanie Seltmann, Yongqun He GENEAe018-A Stefanie Seltmann, Yongqun He GENEAe019-A Stefanie Seltmann, Yongqun He GENEAe020-A Stefanie Seltmann, Yongqun He GENEAe021-A Stefanie Seltmann, Yongqun He GENYOi004-A Stefanie Seltmann, Yongqun He GUCASe001-A Stefanie Seltmann, Yongqun He GUCASe002-A Stefanie Seltmann, Yongqun He GZHMCe001-A Stefanie Seltmann, Yongqun He GZHMCe002-A Stefanie Seltmann, Yongqun He GZHMCe003-A Stefanie Seltmann, Yongqun He GZHMCe004-A Stefanie Seltmann, Yongqun He HADe001-A Stefanie Seltmann, Yongqun He HADe002-A Stefanie Seltmann, Yongqun He HADe003-A Stefanie Seltmann, Yongqun He HADe004-A Stefanie Seltmann, Yongqun He HADe005-A Stefanie Seltmann, Yongqun He HADe006-A Stefanie Seltmann, Yongqun He HADe007-A Stefanie Seltmann, Yongqun He HADe008-A Stefanie Seltmann, Yongqun He HADe009-A Stefanie Seltmann, Yongqun He HEBHMUi001-A Stefanie Seltmann, Yongqun He HMGUi001-A Stefanie Seltmann, Yongqun He HUBi001-A Stefanie Seltmann, Yongqun He HUJIe001-A Stefanie Seltmann, Yongqun He HUSTe001-A Stefanie Seltmann, Yongqun He HUSTe002-A Stefanie Seltmann, Yongqun He HVRDe001-A Stefanie Seltmann, Yongqun He HVRDe002-A Stefanie Seltmann, Yongqun He HVRDe004-A Stefanie Seltmann, Yongqun He HVRDe005-A Stefanie Seltmann, Yongqun He HVRDe006-A Stefanie Seltmann, Yongqun He HVRDe007-A Stefanie Seltmann, Yongqun He HVRDe008-A Stefanie Seltmann, Yongqun He HVRDe009-A Stefanie Seltmann, Yongqun He HVRDe010-A Stefanie Seltmann, Yongqun He HVRDe011-A Stefanie Seltmann, Yongqun He HVRDe012-A Stefanie Seltmann, Yongqun He HVRDe013-A Stefanie Seltmann, Yongqun He HVRDe014-A Stefanie Seltmann, Yongqun He HVRDe015-A Stefanie Seltmann, Yongqun He HVRDe016-A Stefanie Seltmann, Yongqun He HVRDe017-A Stefanie Seltmann, Yongqun He HVRDi004-B Stefanie Seltmann, Yongqun He HVRDi005-A Stefanie Seltmann, Yongqun He HVRDi006-A Stefanie Seltmann, Yongqun He HVRDi007-A Stefanie Seltmann, Yongqun He HVRDi008-A Stefanie Seltmann, Yongqun He HVRDi009-A Stefanie Seltmann, Yongqun He HVRDi010-A Stefanie Seltmann, Yongqun He IAIi001-A Stefanie Seltmann, Yongqun He IAIi002-A Stefanie Seltmann, Yongqun He IAIi003-A Stefanie Seltmann, Yongqun He IAIi004-A Stefanie Seltmann, Yongqun He IBMSi001-A Stefanie Seltmann, Yongqun He IBMSi002-A Stefanie Seltmann, Yongqun He IBMSi003-A Stefanie Seltmann, Yongqun He IBPi001-A Stefanie Seltmann, Yongqun He IBPi002-A Stefanie Seltmann, Yongqun He ICAGi001-A Stefanie Seltmann, Yongqun He ICGi005-A Stefanie Seltmann, Yongqun He ICGi005-B Stefanie Seltmann, Yongqun He ICGi006-A Stefanie Seltmann, Yongqun He ICGi006-B Stefanie Seltmann, Yongqun He ICGi007-A Stefanie Seltmann, Yongqun He ICGi008-A Stefanie Seltmann, Yongqun He ICGi008-B Stefanie Seltmann, Yongqun He IDISi001-A Stefanie Seltmann, Yongqun He IDVi001-A Stefanie Seltmann, Yongqun He IDVi002-A Stefanie Seltmann, Yongqun He IMGTi001-A Stefanie Seltmann, Yongqun He IMGTi001-B Stefanie Seltmann, Yongqun He IMGTi003-A Stefanie Seltmann, Yongqun He IMHe001-A Stefanie Seltmann, Yongqun He IMHe002-A Stefanie Seltmann, Yongqun He IMHe003-A Stefanie Seltmann, Yongqun He IMHe004-A Stefanie Seltmann, Yongqun He IMHe005-A Stefanie Seltmann, Yongqun He IMHe006-A Stefanie Seltmann, Yongqun He IMHe007-A Stefanie Seltmann, Yongqun He IMHe008-A Stefanie Seltmann, Yongqun He IMHe009-A Stefanie Seltmann, Yongqun He IMHe010-A Stefanie Seltmann, Yongqun He IMHe011-A Stefanie Seltmann, Yongqun He IMHe012-A Stefanie Seltmann, Yongqun He IMHe013-A Stefanie Seltmann, Yongqun He IMHe014-A Stefanie Seltmann, Yongqun He IMHe015-A Stefanie Seltmann, Yongqun He IMHe016-A Stefanie Seltmann, Yongqun He IMHe017-A Stefanie Seltmann, Yongqun He IMHe018-A Stefanie Seltmann, Yongqun He INSRMe001-A Stefanie Seltmann, Yongqun He INSRMe002-A Stefanie Seltmann, Yongqun He INSRMe003-A Stefanie Seltmann, Yongqun He INSRMe004-A Stefanie Seltmann, Yongqun He INSRMe005-A Stefanie Seltmann, Yongqun He INSRMe006-A Stefanie Seltmann, Yongqun He INSRMe007-A Stefanie Seltmann, Yongqun He INSRMe008-A Stefanie Seltmann, Yongqun He INSRMe009-A Stefanie Seltmann, Yongqun He INSRMe010-A Stefanie Seltmann, Yongqun He INSRMe011-A Stefanie Seltmann, Yongqun He INSRMe012-A Stefanie Seltmann, Yongqun He INSRMe013-A Stefanie Seltmann, Yongqun He INSRMe014-A Stefanie Seltmann, Yongqun He INSRMe015-A Stefanie Seltmann, Yongqun He INSRMe016-A Stefanie Seltmann, Yongqun He INSRMe017-A Stefanie Seltmann, Yongqun He INSRMe018-A Stefanie Seltmann, Yongqun He IRFMNi001-A Stefanie Seltmann, Yongqun He IRFMNi002-A Stefanie Seltmann, Yongqun He IRFMNi002-B Stefanie Seltmann, Yongqun He IRMBi001-A Stefanie Seltmann, Yongqun He IRMBi002-A Stefanie Seltmann, Yongqun He ISMMSi001-A Stefanie Seltmann, Yongqun He ISMMSi001-B Stefanie Seltmann, Yongqun He ISMMSi002-A Stefanie Seltmann, Yongqun He ISMMSi002-B Stefanie Seltmann, Yongqun He ITSe001-A Stefanie Seltmann, Yongqun He JNCSRe001-A Stefanie Seltmann, Yongqun He JNCSRe002-A Stefanie Seltmann, Yongqun He KCLe001-A Stefanie Seltmann, Yongqun He KCLe002-A Stefanie Seltmann, Yongqun He KCLe003-A Stefanie Seltmann, Yongqun He KCLe004-A Stefanie Seltmann, Yongqun He KCLe005-A Stefanie Seltmann, Yongqun He KCLe006-A Stefanie Seltmann, Yongqun He KCLe007-A Stefanie Seltmann, Yongqun He KCLe008-A Stefanie Seltmann, Yongqun He KCLe009-A Stefanie Seltmann, Yongqun He KCLe010-A Stefanie Seltmann, Yongqun He KCLe011-A Stefanie Seltmann, Yongqun He KCLe012-A Stefanie Seltmann, Yongqun He KCLe013-A Stefanie Seltmann, Yongqun He KCLe014-A Stefanie Seltmann, Yongqun He KCLe015-A Stefanie Seltmann, Yongqun He KCLi001-A Stefanie Seltmann, Yongqun He KCLi002-A Stefanie Seltmann, Yongqun He KCLi003-A Stefanie Seltmann, Yongqun He KGUi001-A Stefanie Seltmann, Yongqun He KGUi002-A Stefanie Seltmann, Yongqun He KIe001-A Stefanie Seltmann, Yongqun He KIe002-A Stefanie Seltmann, Yongqun He KIe003-A Stefanie Seltmann, Yongqun He KIe004-A Stefanie Seltmann, Yongqun He KIe005-A Stefanie Seltmann, Yongqun He KIe006-A Stefanie Seltmann, Yongqun He KIe007-A Stefanie Seltmann, Yongqun He KIe008-A Stefanie Seltmann, Yongqun He KIe009-A Stefanie Seltmann, Yongqun He KIe010-A Stefanie Seltmann, Yongqun He KIe011-A Stefanie Seltmann, Yongqun He KIe012-A Stefanie Seltmann, Yongqun He KIe013-A Stefanie Seltmann, Yongqun He KIe014-A Stefanie Seltmann, Yongqun He KIe015-A Stefanie Seltmann, Yongqun He KIe016-A Stefanie Seltmann, Yongqun He KIe017-A Stefanie Seltmann, Yongqun He KIe018-A Stefanie Seltmann, Yongqun He KIe019-A Stefanie Seltmann, Yongqun He KIe020-A Stefanie Seltmann, Yongqun He KIe021-A Stefanie Seltmann, Yongqun He KIe022-A Stefanie Seltmann, Yongqun He KIe023-A Stefanie Seltmann, Yongqun He KIe024-A Stefanie Seltmann, Yongqun He KIe025-A Stefanie Seltmann, Yongqun He KIe026-A Stefanie Seltmann, Yongqun He KIe027-A Stefanie Seltmann, Yongqun He KIe028-A Stefanie Seltmann, Yongqun He KIe029-A Stefanie Seltmann, Yongqun He KIe030-A Stefanie Seltmann, Yongqun He KIe031-A Stefanie Seltmann, Yongqun He KIe032-A Stefanie Seltmann, Yongqun He KIe033-A Stefanie Seltmann, Yongqun He KLRMMEi001-A Stefanie Seltmann, Yongqun He KMUe001-A Stefanie Seltmann, Yongqun He KMUe002-A Stefanie Seltmann, Yongqun He KMUe003-A Stefanie Seltmann, Yongqun He KMUe004-A Stefanie Seltmann, Yongqun He KMUe005-A Stefanie Seltmann, Yongqun He KSCBi001-A Stefanie Seltmann, Yongqun He KSCBi002-A Stefanie Seltmann, Yongqun He KSCBi002-B Stefanie Seltmann, Yongqun He KSCBi003-A Stefanie Seltmann, Yongqun He KSCBi005-A Stefanie Seltmann, Yongqun He KUe001-A Stefanie Seltmann, Yongqun He KUe002-A Stefanie Seltmann, Yongqun He KUe003-A Stefanie Seltmann, Yongqun He KUe004-A Stefanie Seltmann, Yongqun He KUe005-A Stefanie Seltmann, Yongqun He KUe006-A Stefanie Seltmann, Yongqun He KUe007-A Stefanie Seltmann, Yongqun He KUe008-A Stefanie Seltmann, Yongqun He KUe009-A Stefanie Seltmann, Yongqun He KUe010-A Stefanie Seltmann, Yongqun He KUe011-A Stefanie Seltmann, Yongqun He KUe012-A Stefanie Seltmann, Yongqun He KUe013-A Stefanie Seltmann, Yongqun He KUe014-A Stefanie Seltmann, Yongqun He KUe015-A Stefanie Seltmann, Yongqun He KUIFMSi004-A Stefanie Seltmann, Yongqun He KUIFMSi009-A Stefanie Seltmann, Yongqun He KUIFMSi009-B Stefanie Seltmann, Yongqun He KUIFMSi011-A Stefanie Seltmann, Yongqun He KUIFMSi011-B Stefanie Seltmann, Yongqun He KUIFMSi011-C Stefanie Seltmann, Yongqun He KUIFMSi011-D Stefanie Seltmann, Yongqun He KUIFMSi011-E Stefanie Seltmann, Yongqun He KUIMSe001-A Stefanie Seltmann, Yongqun He KUIMSe002-A Stefanie Seltmann, Yongqun He KUIMSe003-A Stefanie Seltmann, Yongqun He LEIi004-A Stefanie Seltmann, Yongqun He LEIi005-A Stefanie Seltmann, Yongqun He LEIi006-A Stefanie Seltmann, Yongqun He LUBi001-A Stefanie Seltmann, Yongqun He LUBi001-B Stefanie Seltmann, Yongqun He LUBi001-C Stefanie Seltmann, Yongqun He LUMCe001-A Stefanie Seltmann, Yongqun He LUMCe002-A Stefanie Seltmann, Yongqun He LUMCe003-A Stefanie Seltmann, Yongqun He LUMCe004-A Stefanie Seltmann, Yongqun He LUMCi004-A Stefanie Seltmann, Yongqun He MHHi001-A Stefanie Seltmann, Yongqun He MHHi002-A Stefanie Seltmann, Yongqun He MHHi003-A Stefanie Seltmann, Yongqun He MHHi004-A Stefanie Seltmann, Yongqun He MHHi005-A Stefanie Seltmann, Yongqun He MHHi006-A Stefanie Seltmann, Yongqun He MIHe001-A Stefanie Seltmann, Yongqun He MIHe002-A Stefanie Seltmann, Yongqun He MIHe003-A Stefanie Seltmann, Yongqun He MIHe004-A Stefanie Seltmann, Yongqun He MIHe005-A Stefanie Seltmann, Yongqun He MIHe006-A Stefanie Seltmann, Yongqun He MIHe007-A Stefanie Seltmann, Yongqun He MIHe008-A Stefanie Seltmann, Yongqun He MIHe009-A Stefanie Seltmann, Yongqun He MIZMe001-A Stefanie Seltmann, Yongqun He MIZMe002-A Stefanie Seltmann, Yongqun He MIZMe003-A Stefanie Seltmann, Yongqun He MIZMe004-A Stefanie Seltmann, Yongqun He MIZMe005-A Stefanie Seltmann, Yongqun He MIZMe006-A Stefanie Seltmann, Yongqun He MIZMe007-A Stefanie Seltmann, Yongqun He MIZMe008-A Stefanie Seltmann, Yongqun He MIZMe009-A Stefanie Seltmann, Yongqun He MIZMe010-A Stefanie Seltmann, Yongqun He MIZMe011-A Stefanie Seltmann, Yongqun He MIZMe012-A Stefanie Seltmann, Yongqun He MIZMe013-A Stefanie Seltmann, Yongqun He MIZMe014-A Stefanie Seltmann, Yongqun He MIZMe015-A Stefanie Seltmann, Yongqun He MLi002-A Stefanie Seltmann, Yongqun He MPIi001-A Stefanie Seltmann, Yongqun He MPIi002-A Stefanie Seltmann, Yongqun He MPIi003-A Stefanie Seltmann, Yongqun He MPIi005-A Stefanie Seltmann, Yongqun He MSHRIe001-A Stefanie Seltmann, Yongqun He MSHRIe002-A Stefanie Seltmann, Yongqun He MUi010-A Stefanie Seltmann, Yongqun He MUi015-A Stefanie Seltmann, Yongqun He MUNIe001-A Stefanie Seltmann, Yongqun He MUNIe002-A Stefanie Seltmann, Yongqun He MUNIe003-A Stefanie Seltmann, Yongqun He MUNIe004-A Stefanie Seltmann, Yongqun He MUNIe005-A Stefanie Seltmann, Yongqun He MUNIe006-A Stefanie Seltmann, Yongqun He MUNIe007-A Stefanie Seltmann, Yongqun He MUNIi001-A Stefanie Seltmann, Yongqun He MUNIi002-A Stefanie Seltmann, Yongqun He MUNIi003-A Stefanie Seltmann, Yongqun He MUNIi004-A Stefanie Seltmann, Yongqun He NERCe002-A Stefanie Seltmann, Yongqun He NERCe003-A Stefanie Seltmann, Yongqun He NIRRHe001-A Stefanie Seltmann, Yongqun He NIRRHe002-A Stefanie Seltmann, Yongqun He NTUe001-A Stefanie Seltmann, Yongqun He NTUe002-A Stefanie Seltmann, Yongqun He NTUe003-A Stefanie Seltmann, Yongqun He NUIGi001-A Stefanie Seltmann, Yongqun He NYSCFe001-A Stefanie Seltmann, Yongqun He NYSCFe002-A Stefanie Seltmann, Yongqun He NYSCFe003-A Stefanie Seltmann, Yongqun He OSRi001-A Stefanie Seltmann, Yongqun He OSRi004-A Stefanie Seltmann, Yongqun He PCIi001-A Stefanie Seltmann, Yongqun He PCIi002-A Stefanie Seltmann, Yongqun He PCIi003-A Stefanie Seltmann, Yongqun He PCIi004-A Stefanie Seltmann, Yongqun He PCIi005-A Stefanie Seltmann, Yongqun He PFIZi001-A Stefanie Seltmann, Yongqun He PFIZi002-A Stefanie Seltmann, Yongqun He PFIZi003-A Stefanie Seltmann, Yongqun He PFIZi004-A Stefanie Seltmann, Yongqun He PFIZi009-A Stefanie Seltmann, Yongqun He PFIZi013-A Stefanie Seltmann, Yongqun He PFIZi014-A Stefanie Seltmann, Yongqun He PFIZi015-A Stefanie Seltmann, Yongqun He PFIZi016-A Stefanie Seltmann, Yongqun He PFIZi017-A Stefanie Seltmann, Yongqun He PFIZi018-A Stefanie Seltmann, Yongqun He PFIZi019-A Stefanie Seltmann, Yongqun He PFIZi021-A Stefanie Seltmann, Yongqun He PFIZi022-A Stefanie Seltmann, Yongqun He PFIZi023-A Stefanie Seltmann, Yongqun He PFIZi024-A Stefanie Seltmann, Yongqun He PFIZi025-A Stefanie Seltmann, Yongqun He PFIZi027-A Stefanie Seltmann, Yongqun He PFIZi028-A Stefanie Seltmann, Yongqun He PFIZi029-A Stefanie Seltmann, Yongqun He PFIZi030-A Stefanie Seltmann, Yongqun He PFIZi031-A Stefanie Seltmann, Yongqun He PFIZi032-A Stefanie Seltmann, Yongqun He POWHe001-A Stefanie Seltmann, Yongqun He POWHe002-A Stefanie Seltmann, Yongqun He RASe001-A Stefanie Seltmann, Yongqun He RASe002-A Stefanie Seltmann, Yongqun He RASe003-A Stefanie Seltmann, Yongqun He RBi001-A Stefanie Seltmann, Yongqun He RCe005-A Stefanie Seltmann, Yongqun He RCe006-A Stefanie Seltmann, Yongqun He RCe007-A Stefanie Seltmann, Yongqun He RCe008-A Stefanie Seltmann, Yongqun He RCe009-A Stefanie Seltmann, Yongqun He RCe010-A Stefanie Seltmann, Yongqun He RCe011-A Stefanie Seltmann, Yongqun He RCe012-A Stefanie Seltmann, Yongqun He RCe013-A Stefanie Seltmann, Yongqun He RCe014-A Stefanie Seltmann, Yongqun He RCe015-A Stefanie Seltmann, Yongqun He RCe016-A Stefanie Seltmann, Yongqun He RCe017-A Stefanie Seltmann, Yongqun He RCe018-A Stefanie Seltmann, Yongqun He RCe019-A Stefanie Seltmann, Yongqun He RCe020-A Stefanie Seltmann, Yongqun He RCe021-A Stefanie Seltmann, Yongqun He RCi001-A Stefanie Seltmann, Yongqun He RCi001-B Stefanie Seltmann, Yongqun He RCi002-A Stefanie Seltmann, Yongqun He RCi002-B Stefanie Seltmann, Yongqun He RCi003-A Stefanie Seltmann, Yongqun He RCi003-B Stefanie Seltmann, Yongqun He RCi004-A Stefanie Seltmann, Yongqun He RCi004-B Stefanie Seltmann, Yongqun He RCi005-A Stefanie Seltmann, Yongqun He RCi006-A Stefanie Seltmann, Yongqun He RCi007-C Stefanie Seltmann, Yongqun He RCi009-A Stefanie Seltmann, Yongqun He RCSIi002-A Stefanie Seltmann, Yongqun He RCSIi003-A Stefanie Seltmann, Yongqun He RCSIi004-A Stefanie Seltmann, Yongqun He RCSIi005-A Stefanie Seltmann, Yongqun He REGUi001-A Stefanie Seltmann, Yongqun He REGUi002-A Stefanie Seltmann, Yongqun He RGIe001-A Stefanie Seltmann, Yongqun He RGIe002-A Stefanie Seltmann, Yongqun He RGIe003-A Stefanie Seltmann, Yongqun He RGIe004-A Stefanie Seltmann, Yongqun He RGIe005-A Stefanie Seltmann, Yongqun He RGIe006-A Stefanie Seltmann, Yongqun He RGIe007-A Stefanie Seltmann, Yongqun He RGIe008-A Stefanie Seltmann, Yongqun He RGIe009-A Stefanie Seltmann, Yongqun He RGIe010-A Stefanie Seltmann, Yongqun He RGIe011-A Stefanie Seltmann, Yongqun He RGIe012-A Stefanie Seltmann, Yongqun He RGIe013-A Stefanie Seltmann, Yongqun He RGIe014-A Stefanie Seltmann, Yongqun He RGIe015-A Stefanie Seltmann, Yongqun He RGIe016-A Stefanie Seltmann, Yongqun He RGIe017-A Stefanie Seltmann, Yongqun He RGIe018-A Stefanie Seltmann, Yongqun He RGIe019-A Stefanie Seltmann, Yongqun He RGIe020-A Stefanie Seltmann, Yongqun He RGIe021-A Stefanie Seltmann, Yongqun He RGIe022-A Stefanie Seltmann, Yongqun He RGIe023-A Stefanie Seltmann, Yongqun He RGIe024-A Stefanie Seltmann, Yongqun He RGIe025-A Stefanie Seltmann, Yongqun He RGIe026-A Stefanie Seltmann, Yongqun He RGIe027-A Stefanie Seltmann, Yongqun He RGIe028-A Stefanie Seltmann, Yongqun He RGIe029-A Stefanie Seltmann, Yongqun He RGIe030-A Stefanie Seltmann, Yongqun He RGIe031-A Stefanie Seltmann, Yongqun He RGIe032-A Stefanie Seltmann, Yongqun He RGIe033-A Stefanie Seltmann, Yongqun He RGIe034-A Stefanie Seltmann, Yongqun He RGIe035-A Stefanie Seltmann, Yongqun He RGIe036-A Stefanie Seltmann, Yongqun He RGIe037-A Stefanie Seltmann, Yongqun He RGIe038-A Stefanie Seltmann, Yongqun He RGIe039-A Stefanie Seltmann, Yongqun He RGIe040-A Stefanie Seltmann, Yongqun He RGIe041-A Stefanie Seltmann, Yongqun He RGIe042-A Stefanie Seltmann, Yongqun He RGIe043-A Stefanie Seltmann, Yongqun He RGIe044-A Stefanie Seltmann, Yongqun He RGIe045-A Stefanie Seltmann, Yongqun He RGIe046-A Stefanie Seltmann, Yongqun He RGIe047-A Stefanie Seltmann, Yongqun He RGIe048-A Stefanie Seltmann, Yongqun He RGIe049-A Stefanie Seltmann, Yongqun He RGIe050-A Stefanie Seltmann, Yongqun He RGIe051-A Stefanie Seltmann, Yongqun He RGIe052-A Stefanie Seltmann, Yongqun He RGIe053-A Stefanie Seltmann, Yongqun He RGIe054-A Stefanie Seltmann, Yongqun He RGIe055-A Stefanie Seltmann, Yongqun He RGIe056-A Stefanie Seltmann, Yongqun He RGIe057-A Stefanie Seltmann, Yongqun He RGIe058-A Stefanie Seltmann, Yongqun He RGIe059-A Stefanie Seltmann, Yongqun He RGIe060-A Stefanie Seltmann, Yongqun He RGIe061-A Stefanie Seltmann, Yongqun He RGIe062-A Stefanie Seltmann, Yongqun He RGIe063-A Stefanie Seltmann, Yongqun He RGIe064-A Stefanie Seltmann, Yongqun He RGIe065-A Stefanie Seltmann, Yongqun He RGIe066-A Stefanie Seltmann, Yongqun He RGIe067-A Stefanie Seltmann, Yongqun He RGIe068-A Stefanie Seltmann, Yongqun He RGIe069-A Stefanie Seltmann, Yongqun He RGIe070-A Stefanie Seltmann, Yongqun He RGIe071-A Stefanie Seltmann, Yongqun He RGIe072-A Stefanie Seltmann, Yongqun He RGIe073-A Stefanie Seltmann, Yongqun He RGIe074-A Stefanie Seltmann, Yongqun He RGIe075-A Stefanie Seltmann, Yongqun He RGIe076-A Stefanie Seltmann, Yongqun He RGIe077-A Stefanie Seltmann, Yongqun He RGIe078-A Stefanie Seltmann, Yongqun He RGIe079-A Stefanie Seltmann, Yongqun He RGIe080-A Stefanie Seltmann, Yongqun He RGIe081-A Stefanie Seltmann, Yongqun He RGIe082-A Stefanie Seltmann, Yongqun He RGIe083-A Stefanie Seltmann, Yongqun He RGIe084-A Stefanie Seltmann, Yongqun He RGIe085-A Stefanie Seltmann, Yongqun He RGIe086-A Stefanie Seltmann, Yongqun He RGIe087-A Stefanie Seltmann, Yongqun He RGIe088-A Stefanie Seltmann, Yongqun He RGIe089-A Stefanie Seltmann, Yongqun He RGIe090-A Stefanie Seltmann, Yongqun He RGIe091-A Stefanie Seltmann, Yongqun He RGIe092-A Stefanie Seltmann, Yongqun He RGIe093-A Stefanie Seltmann, Yongqun He RGIe094-A Stefanie Seltmann, Yongqun He RGIe095-A Stefanie Seltmann, Yongqun He RGIe096-A Stefanie Seltmann, Yongqun He RGIe097-A Stefanie Seltmann, Yongqun He RGIe098-A Stefanie Seltmann, Yongqun He RGIe099-A Stefanie Seltmann, Yongqun He RGIe100-A Stefanie Seltmann, Yongqun He RGIe101-A Stefanie Seltmann, Yongqun He RGIe102-A Stefanie Seltmann, Yongqun He RGIe103-A Stefanie Seltmann, Yongqun He RGIe104-A Stefanie Seltmann, Yongqun He RGIe105-A Stefanie Seltmann, Yongqun He RGIe106-A Stefanie Seltmann, Yongqun He RGIe107-A Stefanie Seltmann, Yongqun He RGIe108-A Stefanie Seltmann, Yongqun He RGIe109-A Stefanie Seltmann, Yongqun He RGIe110-A Stefanie Seltmann, Yongqun He RGIe111-A Stefanie Seltmann, Yongqun He RGIe112-A Stefanie Seltmann, Yongqun He RGIe113-A Stefanie Seltmann, Yongqun He RGIe114-A Stefanie Seltmann, Yongqun He RGIe115-A Stefanie Seltmann, Yongqun He RGIe116-A Stefanie Seltmann, Yongqun He RGIe117-A Stefanie Seltmann, Yongqun He RGIe118-A Stefanie Seltmann, Yongqun He RGIe119-A Stefanie Seltmann, Yongqun He RGIe120-A Stefanie Seltmann, Yongqun He RGIe121-A Stefanie Seltmann, Yongqun He RGIe122-A Stefanie Seltmann, Yongqun He RGIe123-A Stefanie Seltmann, Yongqun He RGIe124-A Stefanie Seltmann, Yongqun He RGIe125-A Stefanie Seltmann, Yongqun He RGIe126-A Stefanie Seltmann, Yongqun He RGIe127-A Stefanie Seltmann, Yongqun He RGIe128-A Stefanie Seltmann, Yongqun He RGIe129-A Stefanie Seltmann, Yongqun He RGIe130-A Stefanie Seltmann, Yongqun He RGIe131-A Stefanie Seltmann, Yongqun He RGIe132-A Stefanie Seltmann, Yongqun He RGIe133-A Stefanie Seltmann, Yongqun He RGIe134-A Stefanie Seltmann, Yongqun He RGIe135-A Stefanie Seltmann, Yongqun He RGIe136-A Stefanie Seltmann, Yongqun He RGIe137-A Stefanie Seltmann, Yongqun He RGIe138-A Stefanie Seltmann, Yongqun He RGIe139-A Stefanie Seltmann, Yongqun He RGIe140-A Stefanie Seltmann, Yongqun He RGIe141-A Stefanie Seltmann, Yongqun He RGIe142-A Stefanie Seltmann, Yongqun He RGIe143-A Stefanie Seltmann, Yongqun He RGIe144-A Stefanie Seltmann, Yongqun He RGIe145-A Stefanie Seltmann, Yongqun He RGIe146-A Stefanie Seltmann, Yongqun He RGIe147-A Stefanie Seltmann, Yongqun He RGIe148-A Stefanie Seltmann, Yongqun He RGIe149-A Stefanie Seltmann, Yongqun He RGIe150-A Stefanie Seltmann, Yongqun He RGIe151-A Stefanie Seltmann, Yongqun He RGIe152-A Stefanie Seltmann, Yongqun He RGIe153-A Stefanie Seltmann, Yongqun He RGIe154-A Stefanie Seltmann, Yongqun He RGIe155-A Stefanie Seltmann, Yongqun He RGIe156-A Stefanie Seltmann, Yongqun He RIe001-A Stefanie Seltmann, Yongqun He RIe002-A Stefanie Seltmann, Yongqun He RIe003-A Stefanie Seltmann, Yongqun He RIe004-A Stefanie Seltmann, Yongqun He RIe005-A Stefanie Seltmann, Yongqun He RIe006-A Stefanie Seltmann, Yongqun He RIe007-A Stefanie Seltmann, Yongqun He RIe008-A Stefanie Seltmann, Yongqun He RIe009-A Stefanie Seltmann, Yongqun He RIe010-A Stefanie Seltmann, Yongqun He RIi001-A Stefanie Seltmann, Yongqun He RIi002-A Stefanie Seltmann, Yongqun He RIi003-A Stefanie Seltmann, Yongqun He RIi004-A Stefanie Seltmann, Yongqun He RIi005-A Stefanie Seltmann, Yongqun He RIi006-A Stefanie Seltmann, Yongqun He RIi007-A Stefanie Seltmann, Yongqun He RIi008-A Stefanie Seltmann, Yongqun He RIi009-A Stefanie Seltmann, Yongqun He RIi010-A Stefanie Seltmann, Yongqun He RIi011-A Stefanie Seltmann, Yongqun He RIi012-A Stefanie Seltmann, Yongqun He RIi013-A Stefanie Seltmann, Yongqun He RIi014-A Stefanie Seltmann, Yongqun He RIi015-A Stefanie Seltmann, Yongqun He RIi016-A Stefanie Seltmann, Yongqun He RUCDRi002-A Stefanie Seltmann, Yongqun He RUESe001-A Stefanie Seltmann, Yongqun He RUESe002-A Stefanie Seltmann, Yongqun He SALKe001-A Stefanie Seltmann, Yongqun He SBIi006-A Stefanie Seltmann, Yongqun He SCSe001-A Stefanie Seltmann, Yongqun He SCSe002-A Stefanie Seltmann, Yongqun He SCSe003-A Stefanie Seltmann, Yongqun He SCSe004-A Stefanie Seltmann, Yongqun He SCTi001-A Stefanie Seltmann, Yongqun He SCTi002-A Stefanie Seltmann, Yongqun He SDUe001-A Stefanie Seltmann, Yongqun He SDUe002-A Stefanie Seltmann, Yongqun He SDUe003-A Stefanie Seltmann, Yongqun He SDUe004-A Stefanie Seltmann, Yongqun He SDUe005-A Stefanie Seltmann, Yongqun He SDUe006-A Stefanie Seltmann, Yongqun He SDUe007-A Stefanie Seltmann, Yongqun He SJTUe001-A Stefanie Seltmann, Yongqun He SNUe001-A Stefanie Seltmann, Yongqun He SNUe002-A Stefanie Seltmann, Yongqun He SNUe003-A Stefanie Seltmann, Yongqun He SNUe004-A Stefanie Seltmann, Yongqun He SNUe005-A Stefanie Seltmann, Yongqun He SNUe006-A Stefanie Seltmann, Yongqun He SSCCe001-A Stefanie Seltmann, Yongqun He SSCCe002-A Stefanie Seltmann, Yongqun He SSCCe003-A Stefanie Seltmann, Yongqun He SSCCe004-A Stefanie Seltmann, Yongqun He SSCCe005-A Stefanie Seltmann, Yongqun He SSCCe006-A Stefanie Seltmann, Yongqun He SSCCe007-A Stefanie Seltmann, Yongqun He SSCCe008-A Stefanie Seltmann, Yongqun He SSMUe001-A Stefanie Seltmann, Yongqun He SSMUe002-A Stefanie Seltmann, Yongqun He SSMUe003-A Stefanie Seltmann, Yongqun He SSMUe004-A Stefanie Seltmann, Yongqun He SSMUe005-A Stefanie Seltmann, Yongqun He SSMUe006-A Stefanie Seltmann, Yongqun He SSMUe008-A Stefanie Seltmann, Yongqun He SSMUe009-A Stefanie Seltmann, Yongqun He SSMUe010-A Stefanie Seltmann, Yongqun He STBCi004-B Stefanie Seltmann, Yongqun He STBCi004-C Stefanie Seltmann, Yongqun He STBCi005-B Stefanie Seltmann, Yongqun He STBCi005-C Stefanie Seltmann, Yongqun He STBCi006-A Stefanie Seltmann, Yongqun He STBCi007-A Stefanie Seltmann, Yongqun He STBCi007-B Stefanie Seltmann, Yongqun He STBCi007-C Stefanie Seltmann, Yongqun He STBCi009-A Stefanie Seltmann, Yongqun He STBCi009-B Stefanie Seltmann, Yongqun He STBCi009-C Stefanie Seltmann, Yongqun He STBCi010-A Stefanie Seltmann, Yongqun He STBCi011-A Stefanie Seltmann, Yongqun He STBCi011-B Stefanie Seltmann, Yongqun He STBCi011-C Stefanie Seltmann, Yongqun He STBCi012-A Stefanie Seltmann, Yongqun He STBCi012-B Stefanie Seltmann, Yongqun He STBCi012-C Stefanie Seltmann, Yongqun He STBCi013-A Stefanie Seltmann, Yongqun He STBCi013-B Stefanie Seltmann, Yongqun He STBCi014-A Stefanie Seltmann, Yongqun He STBCi014-B Stefanie Seltmann, Yongqun He STBCi014-C Stefanie Seltmann, Yongqun He STBCi015-A Stefanie Seltmann, Yongqun He STBCi015-B Stefanie Seltmann, Yongqun He STBCi015-C Stefanie Seltmann, Yongqun He STBCi016-A Stefanie Seltmann, Yongqun He STBCi016-B Stefanie Seltmann, Yongqun He STBCi016-C Stefanie Seltmann, Yongqun He STBCi017-A Stefanie Seltmann, Yongqun He STBCi017-B Stefanie Seltmann, Yongqun He STBCi017-C Stefanie Seltmann, Yongqun He STBCi018-A Stefanie Seltmann, Yongqun He STBCi018-B Stefanie Seltmann, Yongqun He STBCi018-C Stefanie Seltmann, Yongqun He STBCi019-A Stefanie Seltmann, Yongqun He STBCi019-B Stefanie Seltmann, Yongqun He STBCi019-C Stefanie Seltmann, Yongqun He STBCi020-A Stefanie Seltmann, Yongqun He STBCi020-B Stefanie Seltmann, Yongqun He STBCi023-A Stefanie Seltmann, Yongqun He STBCi023-B Stefanie Seltmann, Yongqun He STBCi023-C Stefanie Seltmann, Yongqun He STBCi024-A Stefanie Seltmann, Yongqun He STBCi024-B Stefanie Seltmann, Yongqun He STBCi024-C Stefanie Seltmann, Yongqun He STBCi025-A Stefanie Seltmann, Yongqun He STBCi025-B Stefanie Seltmann, Yongqun He STBCi025-C Stefanie Seltmann, Yongqun He STBCi026-A Stefanie Seltmann, Yongqun He STBCi026-B Stefanie Seltmann, Yongqun He STBCi026-C Stefanie Seltmann, Yongqun He STBCi026-D Stefanie Seltmann, Yongqun He STBCi027-A Stefanie Seltmann, Yongqun He STBCi027-B Stefanie Seltmann, Yongqun He STBCi028-A Stefanie Seltmann, Yongqun He STBCi028-B Stefanie Seltmann, Yongqun He STBCi028-C Stefanie Seltmann, Yongqun He STBCi029-A Stefanie Seltmann, Yongqun He STBCi029-B Stefanie Seltmann, Yongqun He STBCi030-A Stefanie Seltmann, Yongqun He STBCi030-B Stefanie Seltmann, Yongqun He STBCi031-A Stefanie Seltmann, Yongqun He STBCi031-B Stefanie Seltmann, Yongqun He STBCi031-C Stefanie Seltmann, Yongqun He STBCi032-A Stefanie Seltmann, Yongqun He STBCi033-A Stefanie Seltmann, Yongqun He STBCi033-B Stefanie Seltmann, Yongqun He STBCi033-C Stefanie Seltmann, Yongqun He STBCi034-A Stefanie Seltmann, Yongqun He STBCi034-B Stefanie Seltmann, Yongqun He STBCi035-A Stefanie Seltmann, Yongqun He STBCi035-B Stefanie Seltmann, Yongqun He STBCi036-A Stefanie Seltmann, Yongqun He STBCi037-A Stefanie Seltmann, Yongqun He STBCi037-B Stefanie Seltmann, Yongqun He STBCi037-C Stefanie Seltmann, Yongqun He STBCi038-A Stefanie Seltmann, Yongqun He STBCi038-B Stefanie Seltmann, Yongqun He STBCi038-C Stefanie Seltmann, Yongqun He STBCi039-A Stefanie Seltmann, Yongqun He STBCi039-B Stefanie Seltmann, Yongqun He STBCi040-A Stefanie Seltmann, Yongqun He STBCi040-B Stefanie Seltmann, Yongqun He STBCi040-C Stefanie Seltmann, Yongqun He STBCi041-A Stefanie Seltmann, Yongqun He STBCi041-B Stefanie Seltmann, Yongqun He STBCi042-A Stefanie Seltmann, Yongqun He STBCi042-B Stefanie Seltmann, Yongqun He STBCi042-C Stefanie Seltmann, Yongqun He STBCi043-A Stefanie Seltmann, Yongqun He STBCi043-B Stefanie Seltmann, Yongqun He STBCi043-C Stefanie Seltmann, Yongqun He STBCi044-A Stefanie Seltmann, Yongqun He STBCi044-B Stefanie Seltmann, Yongqun He STBCi045-A Stefanie Seltmann, Yongqun He STBCi045-B Stefanie Seltmann, Yongqun He STBCi045-C Stefanie Seltmann, Yongqun He STBCi046-A Stefanie Seltmann, Yongqun He STBCi046-B Stefanie Seltmann, Yongqun He STBCi047-A Stefanie Seltmann, Yongqun He STBCi047-B Stefanie Seltmann, Yongqun He STBCi048-A Stefanie Seltmann, Yongqun He STBCi048-B Stefanie Seltmann, Yongqun He STBCi048-C Stefanie Seltmann, Yongqun He STBCi049-A Stefanie Seltmann, Yongqun He STBCi049-B Stefanie Seltmann, Yongqun He STBCi049-C Stefanie Seltmann, Yongqun He STBCi050-A Stefanie Seltmann, Yongqun He STBCi050-B Stefanie Seltmann, Yongqun He STBCi050-C Stefanie Seltmann, Yongqun He STBCi051-A Stefanie Seltmann, Yongqun He STBCi051-B Stefanie Seltmann, Yongqun He STBCi051-C Stefanie Seltmann, Yongqun He STBCi052-A Stefanie Seltmann, Yongqun He STBCi052-B Stefanie Seltmann, Yongqun He STBCi052-C Stefanie Seltmann, Yongqun He STBCi053-A Stefanie Seltmann, Yongqun He STBCi053-B Stefanie Seltmann, Yongqun He STBCi054-A Stefanie Seltmann, Yongqun He STBCi054-B Stefanie Seltmann, Yongqun He STBCi055-A Stefanie Seltmann, Yongqun He STBCi055-B Stefanie Seltmann, Yongqun He STBCi055-C Stefanie Seltmann, Yongqun He STBCi056-A Stefanie Seltmann, Yongqun He STBCi056-B Stefanie Seltmann, Yongqun He STBCi057-A Stefanie Seltmann, Yongqun He STBCi057-B Stefanie Seltmann, Yongqun He STBCi057-C Stefanie Seltmann, Yongqun He STBCi058-A Stefanie Seltmann, Yongqun He STBCi058-B Stefanie Seltmann, Yongqun He STBCi058-C Stefanie Seltmann, Yongqun He STBCi059-A Stefanie Seltmann, Yongqun He STBCi059-B Stefanie Seltmann, Yongqun He STBCi059-C Stefanie Seltmann, Yongqun He STBCi061-A Stefanie Seltmann, Yongqun He STBCi062-A Stefanie Seltmann, Yongqun He STBCi063-A Stefanie Seltmann, Yongqun He STBCi063-B Stefanie Seltmann, Yongqun He STBCi063-C Stefanie Seltmann, Yongqun He STBCi064-A Stefanie Seltmann, Yongqun He STBCi065-A Stefanie Seltmann, Yongqun He STBCi066-A Stefanie Seltmann, Yongqun He STBCi068-A Stefanie Seltmann, Yongqun He STBCi068-B Stefanie Seltmann, Yongqun He STBCi068-C Stefanie Seltmann, Yongqun He STBCi069-A Stefanie Seltmann, Yongqun He STBCi069-B Stefanie Seltmann, Yongqun He STBCi069-C Stefanie Seltmann, Yongqun He STBCi070-A Stefanie Seltmann, Yongqun He STBCi070-B Stefanie Seltmann, Yongqun He STBCi071-A Stefanie Seltmann, Yongqun He STBCi071-B Stefanie Seltmann, Yongqun He STBCi071-C Stefanie Seltmann, Yongqun He STBCi072-A Stefanie Seltmann, Yongqun He STBCi072-B Stefanie Seltmann, Yongqun He STBCi072-C Stefanie Seltmann, Yongqun He STBCi073-A Stefanie Seltmann, Yongqun He STBCi073-B Stefanie Seltmann, Yongqun He STBCi074-A Stefanie Seltmann, Yongqun He STBCi074-B Stefanie Seltmann, Yongqun He STBCi074-C Stefanie Seltmann, Yongqun He STBCi075-A Stefanie Seltmann, Yongqun He STBCi075-B Stefanie Seltmann, Yongqun He STBCi075-C Stefanie Seltmann, Yongqun He STBCi076-A Stefanie Seltmann, Yongqun He STBCi077-A Stefanie Seltmann, Yongqun He STBCi077-B Stefanie Seltmann, Yongqun He STBCi077-C Stefanie Seltmann, Yongqun He STBCi078-A Stefanie Seltmann, Yongqun He STBCi078-B Stefanie Seltmann, Yongqun He STBCi078-C Stefanie Seltmann, Yongqun He STBCi079-A Stefanie Seltmann, Yongqun He STBCi079-B Stefanie Seltmann, Yongqun He STBCi079-C Stefanie Seltmann, Yongqun He STBCi080-A Stefanie Seltmann, Yongqun He STBCi080-B Stefanie Seltmann, Yongqun He STBCi080-C Stefanie Seltmann, Yongqun He STBCi081-A Stefanie Seltmann, Yongqun He STBCi081-B Stefanie Seltmann, Yongqun He STBCi081-C Stefanie Seltmann, Yongqun He STBCi082-A Stefanie Seltmann, Yongqun He STBCi082-B Stefanie Seltmann, Yongqun He STBCi082-C Stefanie Seltmann, Yongqun He STBCi083-A Stefanie Seltmann, Yongqun He STBCi083-B Stefanie Seltmann, Yongqun He STBCi084-A Stefanie Seltmann, Yongqun He STBCi084-B Stefanie Seltmann, Yongqun He STBCi084-C Stefanie Seltmann, Yongqun He STBCi085-A Stefanie Seltmann, Yongqun He STBCi085-B Stefanie Seltmann, Yongqun He STBCi085-C Stefanie Seltmann, Yongqun He STBCi086-A Stefanie Seltmann, Yongqun He STBCi086-B Stefanie Seltmann, Yongqun He STBCi087-A Stefanie Seltmann, Yongqun He STBCi087-B Stefanie Seltmann, Yongqun He STBCi087-C Stefanie Seltmann, Yongqun He STBCi088-A Stefanie Seltmann, Yongqun He STBCi088-B Stefanie Seltmann, Yongqun He STBCi088-C Stefanie Seltmann, Yongqun He STBCi089-A Stefanie Seltmann, Yongqun He STBCi089-B Stefanie Seltmann, Yongqun He STBCi089-C Stefanie Seltmann, Yongqun He STBCi090-A Stefanie Seltmann, Yongqun He STBCi090-B Stefanie Seltmann, Yongqun He STBCi091-A Stefanie Seltmann, Yongqun He STBCi091-B Stefanie Seltmann, Yongqun He STBCi091-C Stefanie Seltmann, Yongqun He STBCi092-A Stefanie Seltmann, Yongqun He STBCi092-B Stefanie Seltmann, Yongqun He STBCi092-C Stefanie Seltmann, Yongqun He STBCi093-A Stefanie Seltmann, Yongqun He STBCi093-B Stefanie Seltmann, Yongqun He STBCi097-A Stefanie Seltmann, Yongqun He STBCi097-B Stefanie Seltmann, Yongqun He STBCi097-C Stefanie Seltmann, Yongqun He STBCi098-A Stefanie Seltmann, Yongqun He STBCi098-B Stefanie Seltmann, Yongqun He STBCi099-A Stefanie Seltmann, Yongqun He STBCi099-B Stefanie Seltmann, Yongqun He STBCi100-A Stefanie Seltmann, Yongqun He STBCi101-A Stefanie Seltmann, Yongqun He STBCi102-A Stefanie Seltmann, Yongqun He STBCi103-A Stefanie Seltmann, Yongqun He STBCi104-A Stefanie Seltmann, Yongqun He STBCi105-A Stefanie Seltmann, Yongqun He STBCi106-A Stefanie Seltmann, Yongqun He STBCi107-A Stefanie Seltmann, Yongqun He STBCi108-A Stefanie Seltmann, Yongqun He STBCi110-A Stefanie Seltmann, Yongqun He STBCi111-A Stefanie Seltmann, Yongqun He STBCi112-A Stefanie Seltmann, Yongqun He STBCi113-A Stefanie Seltmann, Yongqun He STBCi114-A Stefanie Seltmann, Yongqun He STBCi116-A Stefanie Seltmann, Yongqun He STBCi117-A Stefanie Seltmann, Yongqun He STBCi118-A Stefanie Seltmann, Yongqun He STBCi119-A Stefanie Seltmann, Yongqun He STBCi121-A Stefanie Seltmann, Yongqun He STBCi122-A Stefanie Seltmann, Yongqun He STBCi123-A Stefanie Seltmann, Yongqun He STBCi126-A Stefanie Seltmann, Yongqun He STBCi127-A Stefanie Seltmann, Yongqun He STBCi128-A Stefanie Seltmann, Yongqun He STBCi130-A Stefanie Seltmann, Yongqun He STBCi131-A Stefanie Seltmann, Yongqun He STBCi132-A Stefanie Seltmann, Yongqun He STBCi248-A Stefanie Seltmann, Yongqun He STBCi249-A Stefanie Seltmann, Yongqun He STBCi253-A Stefanie Seltmann, Yongqun He STBCi257-A Stefanie Seltmann, Yongqun He STBCi258-A Stefanie Seltmann, Yongqun He STBCi259-A Stefanie Seltmann, Yongqun He STBCi260-A Stefanie Seltmann, Yongqun He STBCi261-A Stefanie Seltmann, Yongqun He STBCi262-A Stefanie Seltmann, Yongqun He STBCi265-A Stefanie Seltmann, Yongqun He STBCi266-A Stefanie Seltmann, Yongqun He STBCi268-A Stefanie Seltmann, Yongqun He STBCi279-A Stefanie Seltmann, Yongqun He STBCi280-A Stefanie Seltmann, Yongqun He STBCi281-A Stefanie Seltmann, Yongqun He STBCi282-A Stefanie Seltmann, Yongqun He STBCi283-A Stefanie Seltmann, Yongqun He STBCi288-A Stefanie Seltmann, Yongqun He STBCi290-A Stefanie Seltmann, Yongqun He STBCi293-A Stefanie Seltmann, Yongqun He STBCi294-A Stefanie Seltmann, Yongqun He SUSMe001-A Stefanie Seltmann, Yongqun He SUSMe002-A Stefanie Seltmann, Yongqun He SUSMe003-A Stefanie Seltmann, Yongqun He SUSMe004-A Stefanie Seltmann, Yongqun He SUSMe005-A Stefanie Seltmann, Yongqun He SUSMe006-A Stefanie Seltmann, Yongqun He SUSMi001-A Stefanie Seltmann, Yongqun He SUSMi002-A Stefanie Seltmann, Yongqun He SYSUe001-A Stefanie Seltmann, Yongqun He SYSUe002-A Stefanie Seltmann, Yongqun He SYSUe003-A Stefanie Seltmann, Yongqun He SYSUe004-A Stefanie Seltmann, Yongqun He SYSUe005-A Stefanie Seltmann, Yongqun He SYSUe006-A Stefanie Seltmann, Yongqun He TECHe001-A Stefanie Seltmann, Yongqun He TECHe002-A Stefanie Seltmann, Yongqun He TECHe003-A Stefanie Seltmann, Yongqun He TECHe004-A Stefanie Seltmann, Yongqun He TIFRe001-A Stefanie Seltmann, Yongqun He TIFRe002-A Stefanie Seltmann, Yongqun He TIFRe003-A Stefanie Seltmann, Yongqun He TMOi001-A Stefanie Seltmann, Yongqun He TRDSi001-A Stefanie Seltmann, Yongqun He TRDSi002-A Stefanie Seltmann, Yongqun He TRDSi004-A Stefanie Seltmann, Yongqun He TUMi001-A Stefanie Seltmann, Yongqun He TUSMi001-A Stefanie Seltmann, Yongqun He TUSMi002-A Stefanie Seltmann, Yongqun He TUSMi003-A Stefanie Seltmann, Yongqun He TUSMi004-A Stefanie Seltmann, Yongqun He TUSMi005-A Stefanie Seltmann, Yongqun He TUSMi006-A Stefanie Seltmann, Yongqun He UBASe001-A Stefanie Seltmann, Yongqun He UBASe002-A Stefanie Seltmann, Yongqun He UBASe003-A Stefanie Seltmann, Yongqun He UCLi001-A Stefanie Seltmann, Yongqun He UCLi002-A Stefanie Seltmann, Yongqun He UCLi003-A Stefanie Seltmann, Yongqun He UCLi004-A Stefanie Seltmann, Yongqun He UCLi004-B Stefanie Seltmann, Yongqun He UCLi004-C Stefanie Seltmann, Yongqun He UCLi005-A Stefanie Seltmann, Yongqun He UCLi006-A Stefanie Seltmann, Yongqun He UCLi009-A Stefanie Seltmann, Yongqun He UCLi009-B Stefanie Seltmann, Yongqun He UCLi010-A Stefanie Seltmann, Yongqun He UCLi010-B Stefanie Seltmann, Yongqun He UCLi011-A Stefanie Seltmann, Yongqun He UCLi012-A Stefanie Seltmann, Yongqun He UCSFe002-A Stefanie Seltmann, Yongqun He UCSFe003-A Stefanie Seltmann, Yongqun He UCSFe004-A Stefanie Seltmann, Yongqun He UCSFe005-A Stefanie Seltmann, Yongqun He UHe001-A Stefanie Seltmann, Yongqun He UHe002-A Stefanie Seltmann, Yongqun He UHe003-A Stefanie Seltmann, Yongqun He UHe004-A Stefanie Seltmann, Yongqun He UHe005-A Stefanie Seltmann, Yongqun He UHe006-A Stefanie Seltmann, Yongqun He UHi001-A Stefanie Seltmann, Yongqun He UHi001-B Stefanie Seltmann, Yongqun He UHOMe001-A Stefanie Seltmann, Yongqun He UJSi001-A Stefanie Seltmann, Yongqun He UKBi001-B Stefanie Seltmann, Yongqun He UKBi002-A Stefanie Seltmann, Yongqun He UKBi003-A Stefanie Seltmann, Yongqun He UKBi004-A Stefanie Seltmann, Yongqun He UKBi005-A Stefanie Seltmann, Yongqun He UKBi006-A Stefanie Seltmann, Yongqun He UKBi007-A Stefanie Seltmann, Yongqun He UKBi008-A Stefanie Seltmann, Yongqun He UKBi010-A Stefanie Seltmann, Yongqun He UKBi011-A Stefanie Seltmann, Yongqun He UKBi012-A Stefanie Seltmann, Yongqun He UKBi013-A Stefanie Seltmann, Yongqun He UKERi001-A Stefanie Seltmann, Yongqun He UKERi002-A Stefanie Seltmann, Yongqun He UKERi003-A Stefanie Seltmann, Yongqun He UKERi004-A Stefanie Seltmann, Yongqun He UKERi005-A Stefanie Seltmann, Yongqun He UKERi006-A Stefanie Seltmann, Yongqun He UKKi006-A Stefanie Seltmann, Yongqun He UKKi007-A Stefanie Seltmann, Yongqun He UKKi007-B Stefanie Seltmann, Yongqun He UKKi008-A Stefanie Seltmann, Yongqun He UKKi009-A Stefanie Seltmann, Yongqun He UKKi009-B Stefanie Seltmann, Yongqun He UKKi011-A Stefanie Seltmann, Yongqun He UKKi012-A Stefanie Seltmann, Yongqun He UKKi016-A Stefanie Seltmann, Yongqun He UKKi016-B Stefanie Seltmann, Yongqun He UKKi016-C Stefanie Seltmann, Yongqun He UKKi017-A Stefanie Seltmann, Yongqun He UKKi017-B Stefanie Seltmann, Yongqun He UKKi017-C Stefanie Seltmann, Yongqun He UKKi018-A Stefanie Seltmann, Yongqun He UKKi018-B Stefanie Seltmann, Yongqun He UKKi018-C Stefanie Seltmann, Yongqun He UKKi019-A Stefanie Seltmann, Yongqun He UKKi019-B Stefanie Seltmann, Yongqun He UKKi019-C Stefanie Seltmann, Yongqun He UKKi020-A Stefanie Seltmann, Yongqun He UKKi020-B Stefanie Seltmann, Yongqun He UKKi020-C Stefanie Seltmann, Yongqun He UKKi020-D Stefanie Seltmann, Yongqun He UKKi021-A Stefanie Seltmann, Yongqun He UKKi021-B Stefanie Seltmann, Yongqun He UKKi022-A Stefanie Seltmann, Yongqun He UKKi022-C Stefanie Seltmann, Yongqun He UKKi022-D Stefanie Seltmann, Yongqun He UKKi023-A Stefanie Seltmann, Yongqun He UKKi023-B Stefanie Seltmann, Yongqun He UKKi023-C Stefanie Seltmann, Yongqun He UKKi024-A Stefanie Seltmann, Yongqun He UKKi024-B Stefanie Seltmann, Yongqun He UKKi024-C Stefanie Seltmann, Yongqun He UKKi025-A Stefanie Seltmann, Yongqun He UKKi025-B Stefanie Seltmann, Yongqun He UKKi025-C Stefanie Seltmann, Yongqun He UKKi026-A Stefanie Seltmann, Yongqun He UKKi026-B Stefanie Seltmann, Yongqun He UKKi026-C Stefanie Seltmann, Yongqun He UKKi027-A Stefanie Seltmann, Yongqun He UKKi027-B Stefanie Seltmann, Yongqun He UKKi027-C Stefanie Seltmann, Yongqun He UKKi028-A Stefanie Seltmann, Yongqun He UKKi028-B Stefanie Seltmann, Yongqun He UKKi028-C Stefanie Seltmann, Yongqun He UKKi029-A Stefanie Seltmann, Yongqun He UKKi029-B Stefanie Seltmann, Yongqun He UKKi029-C Stefanie Seltmann, Yongqun He UKKi030-A Stefanie Seltmann, Yongqun He UKKi030-B Stefanie Seltmann, Yongqun He UKKi030-C Stefanie Seltmann, Yongqun He UKKi031-A Stefanie Seltmann, Yongqun He UKKi031-B Stefanie Seltmann, Yongqun He UKKi031-C Stefanie Seltmann, Yongqun He UKKi032-A Stefanie Seltmann, Yongqun He UKKi032-B Stefanie Seltmann, Yongqun He UKKi032-C Stefanie Seltmann, Yongqun He UKKi034-A Stefanie Seltmann, Yongqun He UKKi034-B Stefanie Seltmann, Yongqun He UKKi034-C Stefanie Seltmann, Yongqun He UKKi035-A Stefanie Seltmann, Yongqun He UKKi035-B Stefanie Seltmann, Yongqun He UKKi035-C Stefanie Seltmann, Yongqun He UKKi036-A Stefanie Seltmann, Yongqun He UKKi036-B Stefanie Seltmann, Yongqun He UKKi036-C Stefanie Seltmann, Yongqun He UKKi037-A Stefanie Seltmann, Yongqun He UKKi037-B Stefanie Seltmann, Yongqun He UKKi037-C Stefanie Seltmann, Yongqun He ULBe001-A Stefanie Seltmann, Yongqun He ULBe002-A Stefanie Seltmann, Yongqun He ULBe003-A Stefanie Seltmann, Yongqun He ULBe004-A Stefanie Seltmann, Yongqun He ULBe005-A Stefanie Seltmann, Yongqun He ULBi003-A Stefanie Seltmann, Yongqun He ULEIi001-A Stefanie Seltmann, Yongqun He UMANe001-A Stefanie Seltmann, Yongqun He UMANe002-A Stefanie Seltmann, Yongqun He UMANe003-A Stefanie Seltmann, Yongqun He UMANe004-A Stefanie Seltmann, Yongqun He UNEWe001-A Stefanie Seltmann, Yongqun He UNEWe002-A Stefanie Seltmann, Yongqun He UNEWe003-A Stefanie Seltmann, Yongqun He UNEWe004-A Stefanie Seltmann, Yongqun He UNEWe005-A Stefanie Seltmann, Yongqun He UNEWe006-A Stefanie Seltmann, Yongqun He UNEWe007-A Stefanie Seltmann, Yongqun He UNEWe008-A Stefanie Seltmann, Yongqun He UNEWe009-A Stefanie Seltmann, Yongqun He UNEWi001-A Stefanie Seltmann, Yongqun He UNEWi002-A Stefanie Seltmann, Yongqun He UNEWi003-A Stefanie Seltmann, Yongqun He UNEWi004-A Stefanie Seltmann, Yongqun He UNEWi005-A Stefanie Seltmann, Yongqun He UNEWi006-A Stefanie Seltmann, Yongqun He UNEWi011-A Stefanie Seltmann, Yongqun He UNEWi017-A Stefanie Seltmann, Yongqun He UNEWi018-A Stefanie Seltmann, Yongqun He UNEWi019-A Stefanie Seltmann, Yongqun He UNEWi021-A Stefanie Seltmann, Yongqun He UNEWi021-B Stefanie Seltmann, Yongqun He UNEWi021-C Stefanie Seltmann, Yongqun He UNEWi022-A Stefanie Seltmann, Yongqun He UNEWi022-B Stefanie Seltmann, Yongqun He UNEWi022-C Stefanie Seltmann, Yongqun He UNEWi023-A Stefanie Seltmann, Yongqun He UNEWi023-B Stefanie Seltmann, Yongqun He UNEWi023-C Stefanie Seltmann, Yongqun He UNEWi024-A Stefanie Seltmann, Yongqun He UNEWi024-B Stefanie Seltmann, Yongqun He UNEWi024-C Stefanie Seltmann, Yongqun He UNEWi025-A Stefanie Seltmann, Yongqun He UNEWi025-B Stefanie Seltmann, Yongqun He UNEWi025-C Stefanie Seltmann, Yongqun He UNEWi026-A Stefanie Seltmann, Yongqun He UNEWi026-B Stefanie Seltmann, Yongqun He UNEWi026-C Stefanie Seltmann, Yongqun He UNEWi027-A Stefanie Seltmann, Yongqun He UNIGEe001-A Stefanie Seltmann, Yongqun He UNOTe001-A Stefanie Seltmann, Yongqun He UNOTe002-A Stefanie Seltmann, Yongqun He UODi001-A Stefanie Seltmann, Yongqun He UOSe001-A Stefanie Seltmann, Yongqun He UOSe003-A Stefanie Seltmann, Yongqun He UOSe006-A Stefanie Seltmann, Yongqun He UOSe007-A Stefanie Seltmann, Yongqun He UOSe008-A Stefanie Seltmann, Yongqun He UOSe009-A Stefanie Seltmann, Yongqun He UOSe010-A Stefanie Seltmann, Yongqun He UOSe011-A Stefanie Seltmann, Yongqun He UOSe012-A Stefanie Seltmann, Yongqun He UOSe013-A Stefanie Seltmann, Yongqun He UOSe014-A Stefanie Seltmann, Yongqun He UOSe015-A Stefanie Seltmann, Yongqun He UOSe016-A Stefanie Seltmann, Yongqun He UOSe017-A Stefanie Seltmann, Yongqun He UOSe018-A Stefanie Seltmann, Yongqun He UOSi001-A Stefanie Seltmann, Yongqun He UOSi001-B Stefanie Seltmann, Yongqun He UOXFi001-A Stefanie Seltmann, Yongqun He UOXFi001-C Stefanie Seltmann, Yongqun He UOXFi001-D Stefanie Seltmann, Yongqun He UOXFi002-A Stefanie Seltmann, Yongqun He UOXFi002-B Stefanie Seltmann, Yongqun He UOXFi003-A Stefanie Seltmann, Yongqun He UOXFi003-C Stefanie Seltmann, Yongqun He UOXFi010-C Stefanie Seltmann, Yongqun He UPSFRe001-A Stefanie Seltmann, Yongqun He UPSFRe002-A Stefanie Seltmann, Yongqun He UPSFRe003-A Stefanie Seltmann, Yongqun He UPSFRi001-A Stefanie Seltmann, Yongqun He UPSFRi002-A Stefanie Seltmann, Yongqun He UPSFRi003-A Stefanie Seltmann, Yongqun He UPSFRi004-A Stefanie Seltmann, Yongqun He UPSFRi005-A Stefanie Seltmann, Yongqun He UPSFRi006-A Stefanie Seltmann, Yongqun He UPSFRi007-A Stefanie Seltmann, Yongqun He UPSFRi008-A Stefanie Seltmann, Yongqun He UPSFRi009-A Stefanie Seltmann, Yongqun He USCBi001-A Stefanie Seltmann, Yongqun He USPe001-A Stefanie Seltmann, Yongqun He UTAe001-A Stefanie Seltmann, Yongqun He UTAe002-A Stefanie Seltmann, Yongqun He UTAe003-A Stefanie Seltmann, Yongqun He UTAe004-A Stefanie Seltmann, Yongqun He UTAe005-A Stefanie Seltmann, Yongqun He UTAe006-A Stefanie Seltmann, Yongqun He UTAe007-A Stefanie Seltmann, Yongqun He UTAe008-A Stefanie Seltmann, Yongqun He VCYTe001-A Stefanie Seltmann, Yongqun He VIACe001-A Stefanie Seltmann, Yongqun He VIACe002-A Stefanie Seltmann, Yongqun He VIACe003-A Stefanie Seltmann, Yongqun He VIACe004-A Stefanie Seltmann, Yongqun He VIACe005-A Stefanie Seltmann, Yongqun He VUBe001-A Stefanie Seltmann, Yongqun He VUBe002-A Stefanie Seltmann, Yongqun He VUBe003-A Stefanie Seltmann, Yongqun He VUBe004-A Stefanie Seltmann, Yongqun He VUBe005-A Stefanie Seltmann, Yongqun He VUBe006-A Stefanie Seltmann, Yongqun He VUBe007-A Stefanie Seltmann, Yongqun He VUBe008-A Stefanie Seltmann, Yongqun He VUBe009-A Stefanie Seltmann, Yongqun He VUBe010-A Stefanie Seltmann, Yongqun He VUBe011-A Stefanie Seltmann, Yongqun He VUBe012-A Stefanie Seltmann, Yongqun He VUBe013-A Stefanie Seltmann, Yongqun He VUBe014-A Stefanie Seltmann, Yongqun He VUBe015-A Stefanie Seltmann, Yongqun He VUBe016-A Stefanie Seltmann, Yongqun He VUBe017-A Stefanie Seltmann, Yongqun He VUBe018-A Stefanie Seltmann, Yongqun He VUBe019-A Stefanie Seltmann, Yongqun He VUBe020-A Stefanie Seltmann, Yongqun He VUBe021-A Stefanie Seltmann, Yongqun He WAe007-A Stefanie Seltmann, Yongqun He WAe013-A Stefanie Seltmann, Yongqun He WAe014-A Stefanie Seltmann, Yongqun He WAe022-A Stefanie Seltmann, Yongqun He WAi001-A Stefanie Seltmann, Yongqun He WIBRe001-A Stefanie Seltmann, Yongqun He WIBRe002-A Stefanie Seltmann, Yongqun He WIBRe003-A Stefanie Seltmann, Yongqun He WIBRe004-A Stefanie Seltmann, Yongqun He WISCe001-A Stefanie Seltmann, Yongqun He WISCe002-A Stefanie Seltmann, Yongqun He WISCi003-A Stefanie Seltmann, Yongqun He WISCi004-A Stefanie Seltmann, Yongqun He WISCi004-B Stefanie Seltmann, Yongqun He WISCi005-A Stefanie Seltmann, Yongqun He WISCi005-B Stefanie Seltmann, Yongqun He WISCi005-C Stefanie Seltmann, Yongqun He WISCi006-A Stefanie Seltmann, Yongqun He WISCi007-A Stefanie Seltmann, Yongqun He WISCi007-B Stefanie Seltmann, Yongqun He WISCi007-C Stefanie Seltmann, Yongqun He WISCi008-A Stefanie Seltmann, Yongqun He WISCi008-B Stefanie Seltmann, Yongqun He WISCi008-C Stefanie Seltmann, Yongqun He WISCi009-A Stefanie Seltmann, Yongqun He WISCi009-B Stefanie Seltmann, Yongqun He WISi005-A Stefanie Seltmann, Yongqun He WISi006-A Stefanie Seltmann, Yongqun He WTSIi001-A Stefanie Seltmann, Yongqun He WTSIi001-B Stefanie Seltmann, Yongqun He WTSIi002-A Stefanie Seltmann, Yongqun He WTSIi003-A Stefanie Seltmann, Yongqun He WTSIi003-B Stefanie Seltmann, Yongqun He WTSIi004-A Stefanie Seltmann, Yongqun He WTSIi004-B Stefanie Seltmann, Yongqun He WTSIi005-A Stefanie Seltmann, Yongqun He WTSIi005-B Stefanie Seltmann, Yongqun He WTSIi006-A Stefanie Seltmann, Yongqun He WTSIi006-B Stefanie Seltmann, Yongqun He WTSIi007-A Stefanie Seltmann, Yongqun He WTSIi008-A Stefanie Seltmann, Yongqun He WTSIi009-A Stefanie Seltmann, Yongqun He WTSIi010-A Stefanie Seltmann, Yongqun He WTSIi010-B Stefanie Seltmann, Yongqun He WTSIi011-A Stefanie Seltmann, Yongqun He WTSIi011-B Stefanie Seltmann, Yongqun He WTSIi012-A Stefanie Seltmann, Yongqun He WTSIi012-B Stefanie Seltmann, Yongqun He WTSIi013-A Stefanie Seltmann, Yongqun He WTSIi014-A Stefanie Seltmann, Yongqun He WTSIi014-B Stefanie Seltmann, Yongqun He WTSIi015-A Stefanie Seltmann, Yongqun He WTSIi015-B Stefanie Seltmann, Yongqun He WTSIi016-A Stefanie Seltmann, Yongqun He WTSIi017-A Stefanie Seltmann, Yongqun He WTSIi017-B Stefanie Seltmann, Yongqun He WTSIi018-A Stefanie Seltmann, Yongqun He WTSIi018-B Stefanie Seltmann, Yongqun He WTSIi019-A Stefanie Seltmann, Yongqun He WTSIi019-B Stefanie Seltmann, Yongqun He WTSIi020-A Stefanie Seltmann, Yongqun He WTSIi020-B Stefanie Seltmann, Yongqun He WTSIi021-A Stefanie Seltmann, Yongqun He WTSIi021-B Stefanie Seltmann, Yongqun He WTSIi022-A Stefanie Seltmann, Yongqun He WTSIi022-B Stefanie Seltmann, Yongqun He WTSIi023-A Stefanie Seltmann, Yongqun He WTSIi023-B Stefanie Seltmann, Yongqun He WTSIi024-A Stefanie Seltmann, Yongqun He WTSIi025-A Stefanie Seltmann, Yongqun He WTSIi025-B Stefanie Seltmann, Yongqun He WTSIi026-A Stefanie Seltmann, Yongqun He WTSIi027-A Stefanie Seltmann, Yongqun He WTSIi028-A Stefanie Seltmann, Yongqun He WTSIi029-A Stefanie Seltmann, Yongqun He WTSIi030-A Stefanie Seltmann, Yongqun He WTSIi030-B Stefanie Seltmann, Yongqun He WTSIi031-A Stefanie Seltmann, Yongqun He WTSIi032-A Stefanie Seltmann, Yongqun He WTSIi032-B Stefanie Seltmann, Yongqun He WTSIi033-A Stefanie Seltmann, Yongqun He WTSIi034-A Stefanie Seltmann, Yongqun He WTSIi035-A Stefanie Seltmann, Yongqun He WTSIi036-A Stefanie Seltmann, Yongqun He WTSIi037-A Stefanie Seltmann, Yongqun He WTSIi038-A Stefanie Seltmann, Yongqun He WTSIi038-B Stefanie Seltmann, Yongqun He WTSIi039-A Stefanie Seltmann, Yongqun He WTSIi040-A Stefanie Seltmann, Yongqun He WTSIi041-A Stefanie Seltmann, Yongqun He WTSIi041-B Stefanie Seltmann, Yongqun He WTSIi042-A Stefanie Seltmann, Yongqun He WTSIi042-B Stefanie Seltmann, Yongqun He WTSIi044-A Stefanie Seltmann, Yongqun He WTSIi045-A Stefanie Seltmann, Yongqun He WTSIi046-A Stefanie Seltmann, Yongqun He WTSIi046-B Stefanie Seltmann, Yongqun He WTSIi047-A Stefanie Seltmann, Yongqun He WTSIi047-B Stefanie Seltmann, Yongqun He WTSIi048-A Stefanie Seltmann, Yongqun He WTSIi049-A Stefanie Seltmann, Yongqun He WTSIi049-B Stefanie Seltmann, Yongqun He WTSIi050-A Stefanie Seltmann, Yongqun He WTSIi051-A Stefanie Seltmann, Yongqun He WTSIi052-A Stefanie Seltmann, Yongqun He WTSIi053-A Stefanie Seltmann, Yongqun He WTSIi054-A Stefanie Seltmann, Yongqun He WTSIi054-B Stefanie Seltmann, Yongqun He WTSIi055-A Stefanie Seltmann, Yongqun He WTSIi055-B Stefanie Seltmann, Yongqun He WTSIi056-A Stefanie Seltmann, Yongqun He WTSIi057-A Stefanie Seltmann, Yongqun He WTSIi057-B Stefanie Seltmann, Yongqun He WTSIi058-A Stefanie Seltmann, Yongqun He WTSIi059-A Stefanie Seltmann, Yongqun He WTSIi060-A Stefanie Seltmann, Yongqun He WTSIi061-A Stefanie Seltmann, Yongqun He WTSIi062-A Stefanie Seltmann, Yongqun He WTSIi063-A Stefanie Seltmann, Yongqun He WTSIi064-A Stefanie Seltmann, Yongqun He WTSIi065-A Stefanie Seltmann, Yongqun He WTSIi065-B Stefanie Seltmann, Yongqun He WTSIi066-A Stefanie Seltmann, Yongqun He WTSIi066-B Stefanie Seltmann, Yongqun He WTSIi067-A Stefanie Seltmann, Yongqun He WTSIi067-B Stefanie Seltmann, Yongqun He WTSIi068-A Stefanie Seltmann, Yongqun He WTSIi068-B Stefanie Seltmann, Yongqun He WTSIi069-A Stefanie Seltmann, Yongqun He WTSIi070-A Stefanie Seltmann, Yongqun He WTSIi070-B Stefanie Seltmann, Yongqun He WTSIi071-A Stefanie Seltmann, Yongqun He WTSIi071-B Stefanie Seltmann, Yongqun He WTSIi072-A Stefanie Seltmann, Yongqun He WTSIi073-A Stefanie Seltmann, Yongqun He WTSIi073-B Stefanie Seltmann, Yongqun He WTSIi074-A Stefanie Seltmann, Yongqun He WTSIi075-A Stefanie Seltmann, Yongqun He WTSIi076-A Stefanie Seltmann, Yongqun He WTSIi077-A Stefanie Seltmann, Yongqun He WTSIi077-B Stefanie Seltmann, Yongqun He WTSIi078-A Stefanie Seltmann, Yongqun He WTSIi079-A Stefanie Seltmann, Yongqun He WTSIi079-B Stefanie Seltmann, Yongqun He WTSIi080-A Stefanie Seltmann, Yongqun He WTSIi081-A Stefanie Seltmann, Yongqun He WTSIi081-B Stefanie Seltmann, Yongqun He WTSIi082-A Stefanie Seltmann, Yongqun He WTSIi083-A Stefanie Seltmann, Yongqun He WTSIi084-A Stefanie Seltmann, Yongqun He WTSIi084-B Stefanie Seltmann, Yongqun He WTSIi085-A Stefanie Seltmann, Yongqun He 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Seltmann, Yongqun He WTSIi400-A Stefanie Seltmann, Yongqun He WTSIi401-A Stefanie Seltmann, Yongqun He WTSIi402-A Stefanie Seltmann, Yongqun He WTSIi402-B Stefanie Seltmann, Yongqun He WTSIi403-A Stefanie Seltmann, Yongqun He WTSIi403-B Stefanie Seltmann, Yongqun He WTSIi405-A Stefanie Seltmann, Yongqun He WTSIi405-B Stefanie Seltmann, Yongqun He WTSIi406-A Stefanie Seltmann, Yongqun He WTSIi407-A Stefanie Seltmann, Yongqun He WTSIi407-B Stefanie Seltmann, Yongqun He WTSIi408-A Stefanie Seltmann, Yongqun He WTSIi408-B Stefanie Seltmann, Yongqun He WTSIi409-A Stefanie Seltmann, Yongqun He WTSIi410-A Stefanie Seltmann, Yongqun He WTSIi410-B Stefanie Seltmann, Yongqun He WTSIi411-A Stefanie Seltmann, Yongqun He WTSIi412-A Stefanie Seltmann, Yongqun He WTSIi412-B Stefanie Seltmann, Yongqun He WTSIi414-A Stefanie Seltmann, Yongqun He WTSIi414-B Stefanie Seltmann, Yongqun He WTSIi415-A Stefanie Seltmann, Yongqun He WTSIi415-B Stefanie Seltmann, Yongqun He WTSIi416-A Stefanie Seltmann, Yongqun He WTSIi416-B Stefanie Seltmann, Yongqun He WTSIi417-A Stefanie Seltmann, Yongqun He WTSIi417-B Stefanie Seltmann, Yongqun He WTSIi419-A Stefanie Seltmann, Yongqun He WTSIi420-A Stefanie Seltmann, Yongqun He WTSIi420-B Stefanie Seltmann, Yongqun He WTSIi422-A Stefanie Seltmann, Yongqun He WTSIi422-B Stefanie Seltmann, Yongqun He WTSIi424-A Stefanie Seltmann, Yongqun He WTSIi424-B Stefanie Seltmann, Yongqun He WTSIi426-A Stefanie Seltmann, Yongqun He WTSIi428-A Stefanie Seltmann, Yongqun He WTSIi430-A Stefanie Seltmann, Yongqun He WTSIi430-B Stefanie Seltmann, Yongqun He WTSIi431-A Stefanie Seltmann, Yongqun He WTSIi436-A Stefanie Seltmann, Yongqun He WTSIi438-A Stefanie Seltmann, Yongqun He WTSIi439-A Stefanie Seltmann, Yongqun He WTSIi444-A Stefanie Seltmann, Yongqun He WTSIi445-A Stefanie Seltmann, Yongqun He WTSIi446-A Stefanie Seltmann, Yongqun He WTSIi447-A Stefanie Seltmann, Yongqun He WTSIi447-B Stefanie Seltmann, Yongqun He WTSIi448-A Stefanie Seltmann, Yongqun He WTSIi448-B Stefanie Seltmann, Yongqun He WTSIi450-A Stefanie Seltmann, Yongqun He WTSIi450-B Stefanie Seltmann, Yongqun He WTSIi452-A Stefanie Seltmann, Yongqun He WTSIi452-B Stefanie Seltmann, Yongqun He WTSIi453-A Stefanie Seltmann, Yongqun He WTSIi454-A Stefanie Seltmann, Yongqun He WTSIi454-B Stefanie Seltmann, Yongqun He WTSIi455-A Stefanie Seltmann, Yongqun He WTSIi456-A Stefanie Seltmann, Yongqun He WTSIi456-B Stefanie Seltmann, Yongqun He WTSIi457-A Stefanie Seltmann, Yongqun He WTSIi457-B Stefanie Seltmann, Yongqun He WTSIi458-A Stefanie Seltmann, Yongqun He WTSIi458-B Stefanie Seltmann, Yongqun He WTSIi459-A Stefanie Seltmann, Yongqun He WTSIi459-B Stefanie Seltmann, Yongqun He WTSIi460-A Stefanie Seltmann, Yongqun He WTSIi460-B Stefanie Seltmann, Yongqun He WTSIi461-A Stefanie Seltmann, Yongqun He WTSIi461-B Stefanie Seltmann, Yongqun He WTSIi462-A Stefanie Seltmann, Yongqun He WTSIi463-A Stefanie Seltmann, Yongqun He WTSIi463-B Stefanie Seltmann, Yongqun He WTSIi464-A Stefanie Seltmann, Yongqun He WTSIi464-B Stefanie Seltmann, Yongqun He WTSIi465-A Stefanie Seltmann, Yongqun He WTSIi465-B Stefanie Seltmann, Yongqun He WTSIi466-A Stefanie Seltmann, Yongqun He WTSIi466-B Stefanie Seltmann, Yongqun He WTSIi467-A Stefanie Seltmann, Yongqun He WTSIi468-A Stefanie Seltmann, Yongqun He WTSIi469-A Stefanie Seltmann, Yongqun He WTSIi470-A Stefanie Seltmann, Yongqun He WTSIi470-B Stefanie Seltmann, Yongqun He WTSIi472-A Stefanie Seltmann, Yongqun He WTSIi472-B Stefanie Seltmann, Yongqun He WTSIi473-A Stefanie Seltmann, Yongqun He WTSIi473-B Stefanie Seltmann, Yongqun He WTSIi474-A Stefanie Seltmann, Yongqun He WTSIi474-B Stefanie Seltmann, Yongqun He WTSIi475-A Stefanie Seltmann, Yongqun He WTSIi475-B Stefanie Seltmann, Yongqun He WTSIi476-A Stefanie Seltmann, Yongqun He WTSIi477-A Stefanie Seltmann, Yongqun He WTSIi478-A Stefanie Seltmann, Yongqun He WTSIi479-A Stefanie Seltmann, Yongqun He WTSIi479-B Stefanie Seltmann, Yongqun He WTSIi480-A Stefanie Seltmann, Yongqun He WTSIi480-B Stefanie Seltmann, Yongqun He WTSIi481-A Stefanie Seltmann, Yongqun He WTSIi482-A Stefanie Seltmann, Yongqun He WTSIi482-B Stefanie Seltmann, Yongqun He WTSIi483-A Stefanie Seltmann, Yongqun He WTSIi483-B Stefanie Seltmann, Yongqun He WTSIi484-A Stefanie Seltmann, Yongqun He WTSIi484-B Stefanie Seltmann, Yongqun He WTSIi485-A Stefanie Seltmann, Yongqun He WTSIi485-B Stefanie Seltmann, Yongqun He WTSIi486-A Stefanie Seltmann, Yongqun He WTSIi486-B Stefanie Seltmann, Yongqun He WTSIi487-A Stefanie Seltmann, Yongqun He WTSIi488-A Stefanie Seltmann, Yongqun He WTSIi488-B Stefanie Seltmann, Yongqun He WTSIi493-A Stefanie Seltmann, Yongqun He WTSIi493-B Stefanie Seltmann, Yongqun He WTSIi495-A Stefanie Seltmann, Yongqun He WTSIi495-B Stefanie Seltmann, Yongqun He WTSIi496-A Stefanie Seltmann, Yongqun He WTSIi497-A Stefanie Seltmann, Yongqun He WTSIi497-B Stefanie Seltmann, Yongqun He WTSIi498-A Stefanie Seltmann, Yongqun He WTSIi498-B Stefanie Seltmann, Yongqun He WTSIi499-A Stefanie Seltmann, Yongqun He WTSIi501-A Stefanie Seltmann, Yongqun He WTSIi501-B Stefanie Seltmann, Yongqun He WTSIi502-A Stefanie Seltmann, Yongqun He WTSIi503-A Stefanie Seltmann, Yongqun He WTSIi503-B Stefanie Seltmann, Yongqun He WTSIi506-A Stefanie Seltmann, Yongqun He WTSIi506-B Stefanie Seltmann, Yongqun He WTSIi507-A Stefanie Seltmann, Yongqun He WTSIi507-B Stefanie Seltmann, Yongqun He WTSIi508-A Stefanie Seltmann, Yongqun He WTSIi508-B Stefanie Seltmann, Yongqun He WTSIi509-A Stefanie Seltmann, Yongqun He WTSIi510-A Stefanie Seltmann, Yongqun He WTSIi510-B Stefanie Seltmann, Yongqun He WTSIi512-A Stefanie Seltmann, Yongqun He WTSIi514-A Stefanie Seltmann, Yongqun He WTSIi514-B Stefanie Seltmann, Yongqun He WTSIi515-A Stefanie Seltmann, Yongqun He WTSIi516-A Stefanie Seltmann, Yongqun He WTSIi516-B Stefanie Seltmann, Yongqun He WTSIi518-A Stefanie Seltmann, Yongqun He WTSIi519-A Stefanie Seltmann, Yongqun He WTSIi519-B Stefanie Seltmann, Yongqun He WTSIi522-A Stefanie Seltmann, Yongqun He WTSIi522-B Stefanie Seltmann, Yongqun He WTSIi524-A Stefanie Seltmann, Yongqun He WTSIi525-A Stefanie Seltmann, Yongqun He WTSIi525-B Stefanie Seltmann, Yongqun He WTSIi526-A Stefanie Seltmann, Yongqun He WTSIi526-B Stefanie Seltmann, Yongqun He WTSIi527-A Stefanie Seltmann, Yongqun He WTSIi527-B Stefanie Seltmann, Yongqun He WTSIi529-A Stefanie Seltmann, Yongqun He WTSIi529-B Stefanie Seltmann, Yongqun He WTSIi530-A Stefanie Seltmann, Yongqun He WTSIi531-A Stefanie Seltmann, Yongqun He WTSIi531-B Stefanie Seltmann, Yongqun He WTSIi534-A Stefanie Seltmann, Yongqun He WTSIi545-A Stefanie Seltmann, Yongqun He WTSIi548-A Stefanie Seltmann, Yongqun He WTSIi548-B Stefanie Seltmann, Yongqun He WTSIi554-A Stefanie Seltmann, Yongqun He WTSIi555-A Stefanie Seltmann, Yongqun He WTSIi558-A Stefanie Seltmann, Yongqun He WTSIi558-B Stefanie Seltmann, Yongqun He WTSIi560-A Stefanie Seltmann, Yongqun He WTSIi561-A Stefanie Seltmann, Yongqun He WTSIi563-A Stefanie Seltmann, Yongqun He WTSIi564-A Stefanie Seltmann, Yongqun He WTSIi565-A Stefanie Seltmann, Yongqun He WTSIi567-A Stefanie Seltmann, Yongqun He WTSIi568-A Stefanie Seltmann, Yongqun He WTSIi569-A Stefanie Seltmann, Yongqun He WTSIi569-B Stefanie Seltmann, Yongqun He WTSIi570-A Stefanie Seltmann, Yongqun He WTSIi571-A Stefanie Seltmann, Yongqun He WTSIi573-A Stefanie Seltmann, Yongqun He WTSIi573-B Stefanie Seltmann, Yongqun He WTSIi576-A Stefanie Seltmann, Yongqun He WTSIi580-A Stefanie Seltmann, Yongqun He WTSIi582-A Stefanie Seltmann, Yongqun He WTSIi590-A Stefanie Seltmann, Yongqun He WTSIi591-A Stefanie Seltmann, Yongqun He WTSIi591-B Stefanie Seltmann, Yongqun He WTSIi593-A Stefanie Seltmann, Yongqun He WTSIi593-B Stefanie Seltmann, Yongqun He WTSIi594-A Stefanie Seltmann, Yongqun He WTSIi594-B Stefanie Seltmann, Yongqun He WTSIi595-A Stefanie Seltmann, Yongqun He WTSIi595-B Stefanie Seltmann, Yongqun He WTSIi596-A Stefanie Seltmann, Yongqun He WTSIi597-A Stefanie Seltmann, Yongqun He WTSIi598-A Stefanie Seltmann, Yongqun He WTSIi598-B Stefanie Seltmann, Yongqun He WTSIi599-A Stefanie Seltmann, Yongqun He WTSIi599-B Stefanie Seltmann, Yongqun He WTSIi602-A Stefanie Seltmann, Yongqun He WTSIi602-B Stefanie Seltmann, Yongqun He WTSIi603-A Stefanie Seltmann, Yongqun He WTSIi603-B Stefanie Seltmann, Yongqun He WTSIi607-A Stefanie Seltmann, Yongqun He WTSIi607-B Stefanie Seltmann, Yongqun He WTSIi609-A Stefanie Seltmann, Yongqun He WTSIi609-B Stefanie Seltmann, Yongqun He WTSIi610-A Stefanie Seltmann, Yongqun He WTSIi611-A Stefanie Seltmann, Yongqun He WTSIi611-B Stefanie Seltmann, Yongqun He WTSIi612-A Stefanie Seltmann, Yongqun He WTSIi612-B Stefanie Seltmann, Yongqun He WTSIi613-A Stefanie Seltmann, Yongqun He WTSIi613-B Stefanie Seltmann, Yongqun He WTSIi614-A Stefanie Seltmann, Yongqun He WTSIi614-B Stefanie Seltmann, Yongqun He WTSIi615-A Stefanie Seltmann, Yongqun He WTSIi615-B Stefanie Seltmann, Yongqun He WTSIi617-A Stefanie Seltmann, Yongqun He WTSIi617-B Stefanie Seltmann, Yongqun He WTSIi618-A Stefanie Seltmann, Yongqun He WTSIi618-B Stefanie Seltmann, Yongqun He WTSIi619-A Stefanie Seltmann, Yongqun He WTSIi619-B Stefanie Seltmann, Yongqun He WTSIi620-A Stefanie Seltmann, Yongqun He WTSIi620-B Stefanie Seltmann, Yongqun He WTSIi621-A Stefanie Seltmann, Yongqun He WTSIi621-B Stefanie Seltmann, Yongqun He WTSIi622-A Stefanie Seltmann, Yongqun He WTSIi622-B Stefanie Seltmann, Yongqun He WTSIi623-A Stefanie Seltmann, Yongqun He WTSIi623-B Stefanie Seltmann, Yongqun He WTSIi624-A Stefanie Seltmann, Yongqun He WTSIi624-B Stefanie Seltmann, Yongqun He WTSIi626-A Stefanie Seltmann, Yongqun He WTSIi627-A Stefanie Seltmann, Yongqun He WTSIi632-A Stefanie Seltmann, Yongqun He WTSIi632-B Stefanie Seltmann, Yongqun He WTSIi633-A Stefanie Seltmann, Yongqun He WTSIi633-B Stefanie Seltmann, Yongqun He WTSIi634-A Stefanie Seltmann, Yongqun He WTSIi635-A Stefanie Seltmann, Yongqun He WTSIi636-A Stefanie Seltmann, Yongqun He WTSIi638-A Stefanie Seltmann, Yongqun He WTSIi638-B Stefanie Seltmann, Yongqun He WTSIi641-A Stefanie Seltmann, Yongqun He WTSIi641-B Stefanie Seltmann, Yongqun He WTSIi643-A Stefanie Seltmann, Yongqun He WTSIi643-B Stefanie Seltmann, Yongqun He WTSIi644-A Stefanie Seltmann, Yongqun He WTSIi644-B Stefanie Seltmann, Yongqun He WTSIi645-A Stefanie Seltmann, Yongqun He WTSIi646-A Stefanie Seltmann, Yongqun He WTSIi646-B Stefanie Seltmann, Yongqun He WTSIi648-A Stefanie Seltmann, Yongqun He WTSIi648-B Stefanie Seltmann, Yongqun He WTSIi654-A Stefanie Seltmann, Yongqun He WTSIi657-A Stefanie Seltmann, Yongqun He WTSIi657-B Stefanie Seltmann, Yongqun He WTSIi658-A Stefanie Seltmann, Yongqun He WTSIi659-A Stefanie Seltmann, Yongqun He WTSIi659-B Stefanie Seltmann, Yongqun He WTSIi660-A Stefanie Seltmann, Yongqun He WTSIi660-B Stefanie Seltmann, Yongqun He WTSIi661-A Stefanie Seltmann, Yongqun He WTSIi661-B Stefanie Seltmann, Yongqun He WTSIi662-A Stefanie Seltmann, Yongqun He WTSIi662-B Stefanie Seltmann, Yongqun He WTSIi665-A Stefanie Seltmann, Yongqun He WTSIi666-A Stefanie Seltmann, Yongqun He WTSIi666-B Stefanie Seltmann, Yongqun He WTSIi669-A Stefanie Seltmann, Yongqun He WTSIi669-B Stefanie Seltmann, Yongqun He WTSIi670-A Stefanie Seltmann, Yongqun He WTSIi672-A Stefanie Seltmann, Yongqun He WTSIi672-B Stefanie Seltmann, Yongqun He WTSIi673-A Stefanie Seltmann, Yongqun He WTSIi673-B Stefanie Seltmann, Yongqun He WTSIi674-A Stefanie Seltmann, Yongqun He WTSIi674-B Stefanie Seltmann, Yongqun He WTSIi675-A Stefanie Seltmann, Yongqun He WTSIi675-B Stefanie Seltmann, Yongqun He WTSIi676-A Stefanie Seltmann, Yongqun He WTSIi676-B Stefanie Seltmann, Yongqun He WTSIi679-A Stefanie Seltmann, Yongqun He WTSIi679-B Stefanie Seltmann, Yongqun He WTSIi680-A Stefanie Seltmann, Yongqun He WTSIi680-B Stefanie Seltmann, Yongqun He WTSIi682-A Stefanie Seltmann, Yongqun He WTSIi685-A Stefanie Seltmann, Yongqun He WTSIi685-B Stefanie Seltmann, Yongqun He WTSIi686-A Stefanie Seltmann, Yongqun He WTSIi686-B Stefanie Seltmann, Yongqun He WTSIi687-A Stefanie Seltmann, Yongqun He WTSIi687-B Stefanie Seltmann, Yongqun He WTSIi688-A Stefanie Seltmann, Yongqun He WTSIi688-B Stefanie Seltmann, Yongqun He WTSIi689-A Stefanie Seltmann, Yongqun He WTSIi690-A Stefanie Seltmann, Yongqun He WTSIi690-B Stefanie Seltmann, Yongqun He WTSIi691-A Stefanie Seltmann, Yongqun He WTSIi693-A Stefanie Seltmann, Yongqun He WTSIi693-B Stefanie Seltmann, Yongqun He WTSIi694-A Stefanie Seltmann, Yongqun He WTSIi697-A Stefanie Seltmann, Yongqun He WTSIi697-B Stefanie Seltmann, Yongqun He WTSIi698-A Stefanie Seltmann, Yongqun He WTSIi698-B Stefanie Seltmann, Yongqun He WTSIi699-A Stefanie Seltmann, Yongqun He WTSIi699-B Stefanie Seltmann, Yongqun He WTSIi700-A Stefanie Seltmann, Yongqun He WTSIi700-B Stefanie Seltmann, Yongqun He WTSIi703-A Stefanie Seltmann, Yongqun He WTSIi703-B Stefanie Seltmann, Yongqun He WTSIi705-A Stefanie Seltmann, Yongqun He WTSIi709-A Stefanie Seltmann, Yongqun He WTSIi712-A Stefanie Seltmann, Yongqun He WTSIi713-A Stefanie Seltmann, Yongqun He WTSIi713-B Stefanie Seltmann, Yongqun He WTSIi715-A Stefanie Seltmann, Yongqun He WTSIi717-A Stefanie Seltmann, Yongqun He WTSIi717-B Stefanie Seltmann, Yongqun He WTSIi718-A Stefanie Seltmann, Yongqun He WTSIi718-B Stefanie Seltmann, Yongqun He WTSIi720-A Stefanie Seltmann, Yongqun He WTSIi722-A Stefanie Seltmann, Yongqun He WTSIi726-A Stefanie Seltmann, Yongqun He WTSIi727-A Stefanie Seltmann, Yongqun He WTSIi732-A Stefanie Seltmann, Yongqun He WTSIi740-A Stefanie Seltmann, Yongqun He ZZUi004-A Stefanie Seltmann, Yongqun He ZZUi005-A Stefanie Seltmann, Yongqun He ZZUi006-A Stefanie Seltmann, Yongqun He ZZUi007-A Stefanie Seltmann, Yongqun He ZZUi009-A Stefanie Seltmann, Yongqun He ZZUi010-A Stefanie Seltmann, Yongqun He ZZUi011-A Stefanie Seltmann, Yongqun He ZZUi012-A Stefanie Seltmann, Yongqun He ZZUi013-A Stefanie Seltmann, Yongqun He BIHi005-A-4 Stefanie Seltmann & Yongqun He BIHi005-A-5 Stefanie Seltmann & Yongqun He BIONi010-C-2 Stefanie Seltmann & Yongqun He BIONi010-C-3 Stefanie Seltmann & Yongqun He BIONi010-C-4 Stefanie Seltmann & Yongqun He BIONi010-C-5 Stefanie Seltmann & Yongqun He BIONi010-C-6 Stefanie Seltmann & Yongqun He BIONi010-C-7 Stefanie Seltmann & Yongqun He BIONi010-C-8 Stefanie Seltmann & Yongqun He BIONi010-C-9 Stefanie Seltmann & Yongqun He BIONi010-C-10 Stefanie Seltmann & Yongqun He BIONi010-C-11 Stefanie Seltmann & Yongqun He BIONi010-C-12 Stefanie Seltmann & Yongqun He BIONi010-C-13 Stefanie Seltmann & Yongqun He BIONi010-C-15 Stefanie Seltmann & Yongqun He BIONi010-C-17 Stefanie Seltmann & Yongqun He BIONi010-C-18 Stefanie Seltmann & Yongqun He BIONi010-C-19 Stefanie Seltmann & Yongqun He BIONi010-C-24 Stefanie Seltmann & Yongqun He BIONi010-C-25 Stefanie Seltmann & Yongqun He BIONi037-A-1 Stefanie Seltmann & Yongqun He BIONi037-A-2 Stefanie Seltmann & Yongqun He BIONi037-A-3 Stefanie Seltmann & Yongqun He BIONi037-A-4 Stefanie Seltmann & Yongqun He CEBe002-A-1 Stefanie Seltmann & Yongqun He CEBe002-A-2 Stefanie Seltmann & Yongqun He CEBe002-A-3 Stefanie Seltmann & Yongqun He CEBe033-A-1 Stefanie Seltmann & Yongqun He CEBe034-A-1 Stefanie Seltmann & Yongqun He EDi001-A-1 Stefanie Seltmann & Yongqun He EDi001-A-2 Stefanie Seltmann & Yongqun He EDi001-A-3 Stefanie Seltmann & Yongqun He EDi001-A-4 Stefanie Seltmann & Yongqun He ESIBIe003-A-1 Stefanie Seltmann & Yongqun He ESIBIe003-A-2 Stefanie Seltmann & Yongqun He ESIBIe003-A-3 Stefanie Seltmann & Yongqun He ESIBIe003-A-4 Stefanie Seltmann & Yongqun He HMGUi001-A-1 Stefanie Seltmann & Yongqun He HVRDe001-A-1 Stefanie Seltmann & Yongqun He HVRDi004-B-1 Stefanie Seltmann & Yongqun He KIe001-A-1 Stefanie Seltmann & Yongqun He KIe004-A-1 Stefanie Seltmann & Yongqun He KIe006-A-1 Stefanie Seltmann & Yongqun He KIe007-A-1 Stefanie Seltmann & Yongqun He KIe008-A-1 Stefanie Seltmann & Yongqun He KIe009-A-1 Stefanie Seltmann & Yongqun He KIe010-A-1 Stefanie Seltmann & Yongqun He KIe011-A-1 Stefanie Seltmann & Yongqun He KIe012-A-1 Stefanie Seltmann & Yongqun He KIe013-A-1 Stefanie Seltmann & Yongqun He KIe014-A-1 Stefanie Seltmann & Yongqun He KIe015-A-1 Stefanie Seltmann & Yongqun He KIe016-A-1 Stefanie Seltmann & Yongqun He KIe017-A-1 Stefanie Seltmann & Yongqun He KIe018-A-1 Stefanie Seltmann & Yongqun He KIe019-A-1 Stefanie Seltmann & Yongqun He KIe020-A-1 Stefanie Seltmann & Yongqun He KIe021-A-1 Stefanie Seltmann & Yongqun He KIe022-A-1 Stefanie Seltmann & Yongqun He KIe024-A-1 Stefanie Seltmann & Yongqun He KIe024-A-2 Stefanie Seltmann & Yongqun He KIe024-A-3 Stefanie Seltmann & Yongqun He KIe024-A-4 Stefanie Seltmann & Yongqun He KSCBi002-B-1 Stefanie Seltmann & Yongqun He KSCBi005-A-1 Stefanie Seltmann & Yongqun He KUIFMSi004-D Stefanie Seltmann & Yongqun He KUIFMSi004-E Stefanie Seltmann & Yongqun He KUIFMSi004-B Stefanie Seltmann & Yongqun He KUIFMSi004-C Stefanie Seltmann & Yongqun He KUIMSe003-A-1 Stefanie Seltmann & Yongqun He LEIi004-A-1 Stefanie Seltmann & Yongqun He MPIi003-A-1 Stefanie Seltmann & Yongqun He MUNIe001-A-1 Stefanie Seltmann & Yongqun He MUNIe002-A-1 Stefanie Seltmann & Yongqun He MUNIe003-A-1 Stefanie Seltmann & Yongqun He MUNIe004-A-1 Stefanie Seltmann & Yongqun He MUNIe005-A-1 Stefanie Seltmann & Yongqun He MUNIe006-A-1 Stefanie Seltmann & Yongqun He NERCe002-A-1 Stefanie Seltmann & Yongqun He NERCe002-A-2 Stefanie Seltmann & Yongqun He NERCe002-A-3 Stefanie Seltmann & Yongqun He NERCe003-A-1 Stefanie Seltmann & Yongqun He NERCe003-A-2 Stefanie Seltmann & Yongqun He NERCe003-A-3 Stefanie Seltmann & Yongqun He POWHe001-A-1 Stefanie Seltmann & Yongqun He POWHe001-A-2 Stefanie Seltmann & Yongqun He POWHe001-A-3 Stefanie Seltmann & Yongqun He POWHe001-A-4 Stefanie Seltmann & Yongqun He RCe017-A-1 Stefanie Seltmann & Yongqun He RCe019-A-1 Stefanie Seltmann & Yongqun He SNUe003-A-1 Stefanie Seltmann & Yongqun He SNUe004-A-1 Stefanie Seltmann & Yongqun He SNUe005-A-1 Stefanie Seltmann & Yongqun He SNUe006-A-1 Stefanie Seltmann & Yongqun He STBCi006-A-1 Stefanie Seltmann & Yongqun He STBCi006-A-3 Stefanie Seltmann & Yongqun He STBCi006-A-4 Stefanie Seltmann & Yongqun He SUSMi001-A-1 Stefanie Seltmann & Yongqun He TECHe001-A-1 Stefanie Seltmann & Yongqun He TECHe001-A-2 Stefanie Seltmann & Yongqun He TECHe003-A-1 Stefanie Seltmann & Yongqun He TECHe004-A-1 Stefanie Seltmann & Yongqun He TMOi001-A-1 Stefanie Seltmann & Yongqun He TRDSi002-A-1 Stefanie Seltmann & Yongqun He UCSFe003-A-1 Stefanie Seltmann & Yongqun He UKBi011-A-1 Stefanie Seltmann & Yongqun He UKBi011-A-2 Stefanie Seltmann & Yongqun He UKBi011-A-3 Stefanie Seltmann & Yongqun He UKBi011-A-4 Stefanie Seltmann & Yongqun He UPSFRi004-A-1 Stefanie Seltmann & Yongqun He UPSFRi005-A-1 Stefanie Seltmann & Yongqun He VIACe001-A-1 Stefanie Seltmann & Yongqun He VIACe001-A-2 Stefanie Seltmann & Yongqun He VUBe001-A-1 Stefanie Seltmann & Yongqun He WAe001-A-1 Stefanie Seltmann & Yongqun He WAe001-A-10 Stefanie Seltmann & Yongqun He WAe001-A-11 Stefanie Seltmann & Yongqun He WAe009-A-1 Stefanie Seltmann & Yongqun He WAe009-A-2 Stefanie Seltmann & Yongqun He WAe009-A-10 Stefanie Seltmann & Yongqun He WIBRe001-A-1 Stefanie Seltmann & Yongqun He WIBRe001-A-2 Stefanie Seltmann & Yongqun He WISCe001-A-1 Stefanie Seltmann & Yongqun He WTSIi018-B-1 Stefanie Seltmann & Yongqun He WTSIi227-A-1 Stefanie Seltmann & Yongqun He cell cell type cell cell type 细胞 细胞类型 A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CALOHA:TS-2035 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000324 FMA:68646 GO:0005623 KUPO:0000002 The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). VHOG:0001533 WBbt:0004017 XAO:0003012 cell cell A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CALOHA:TS-2035 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000324 FMA:68646 GO:0005623 KUPO:0000002 PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. "...Epithelial cells were harvested from histologically confirmed adenocarcinomas .." The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). VHOG:0001533 WBbt:0004017 XAO:0003012 cell cell 细胞 细胞 细胞的定义是为了表示所有的细胞，因此细胞被定义为一个物质实体，而不是一个解剖结构，这意味着它是一个生物体的一部分（或一个整体）。 解剖学起源（生物体的一部分或来源于生物体）的物质实体，其组成部分是一个被浆膜包围的最大连接的细胞室 primary cultured cell primary cultured cell 原代培养细胞 A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. primary cultured cell A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. primary cultured cell 刚从一种生物体来源分离出来的培养细胞，或者在培养物传代之前从这种细胞的培养物中获得。 原代培养细胞 native cell native cell 自然细胞 A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). CARO:0000013 To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12). cell cell in vivo A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). CARO:0000013 To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12). cell cell in vivo 为了更好地适应单细胞生物体，“体内细胞”已被重新标记为“本地细胞”以更好地表达其寓意 - 也就是说，它是一个多细胞有机体中或自然环境中的细胞。“体内”旨在与“体外”形成对比，“体外”是指为了研究或操作的目的，有意将细胞或其他生物实体置于受控的，非自然的环境中。 （MAH 1.12.12）。 体内细胞 在自然环境中发现的细胞，其包括多细胞生物“体内” 细胞（即生物体的一部分）和环境中（即自然环境的一部分）的单细胞生物体。 细胞 cultured cell cultured cell 培养细胞 A cell in vitro that is or has been maintained or propagated as part of a cell culture. Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. cell cultured cell A cell in vitro that is or has been maintained or propagated as part of a cell culture. Note that this class was re-labeled to 'cultured cell' instead of 'cell line cell', as it intent was clarified to cover any cultured cells of multicellular and unicellular organisms. This includes cells actively being cultured, or cells that have been cultured but are stored in a quiescent state for future use. In having been cultured, cells must establish homeostasis and often replicate in a foreign environment. Accomodation of this stress initiates a selection of cells fit for such challenges, wherein necessary adaptive biochemical and.or genetic changes can occur. These changes can set them apart from the in vivo cells from which they derive, and such changes will typically accumulate and change over increasing time in culture. cell cultured cell 一种体外细胞，其作为或已被维持或增殖为细胞培养物的一部分。 培养细胞 注意到这一类被重新标记为“培养细胞”而不是“细胞系细胞”，因为其目的被澄清以涵盖多细胞和单细胞生物体的任何培养细胞。这包括活化培养的细胞，或已经培养但以静止状态储存以供将来使用的细胞。在培养过程中，细胞必须建立稳态，并经常在外部环境中复制。这种压力适应启动了适应这种挑战的细胞选择，其中可能发生必要的适应性生化和/或遗传改变。这些变化可以使它们与其来源的体内细胞分开，这种变化通常会随着培养时间的增加而积累和改变。 细胞 stem cell stem cell 干细胞 A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. CALOHA:TS-2086 FMA:63368 cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. CALOHA:TS-2086 FMA:63368 cell 一种相对未分化的细胞，其在整个生命中保留分裂和增殖的能力，以提供可分化成特化细胞的祖细胞。 细胞 hematopoietic stem cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. BTO:0000725 CALOHA:TS-0448 FMA:70337 FMA:86475 HSC Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. VHOG:0001485 blood forming stem cell cell colony forming unit hematopoietic hemopoietic stem cell multi fate stem cell multi fate stem cell 多能造血干细胞 A stem cell that can give rise to multiple lineages of cells. FMA:84789 cell multi-fate stem cell multifate stem cell multipotent cell multipotent stem cell A stem cell that can give rise to multiple lineages of cells. FMA:84789 cell multi-fate stem cell multifate stem cell multipotent cell multipotent stem cell 可以产生多种细胞系的干细胞。 多能干细胞(multi-fate stem cell) 多能干细胞(multifate stem cell) 多能干细胞(multipotent stem cell) 多能细胞 细胞 non-terminally differentiated cell A precursor cell with a limited number of potential fates. BTO:0000125 FMA:84782 blast cell cell define using PATO mulit-potent or oligopotent? myoblast A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. BTO:0000222 CALOHA:TS-0650 FBbt:00005083 FMA:70335 VHOG:0001529 cell fibroblast fibroblast 成纤维细胞 A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. BTO:0000452 BTO:0000452 CALOHA:TS-0362 CL:0000057 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496 FMA:63877 James Malone NIFSTD:nlx_cell_20090201 These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#fibroblast VHOG:0001482 cell mouse embryonic fibroblast primary dermal fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. BTO:0000452 BTO:0000452 CALOHA:TS-0362 CL:0000057 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496 FMA:63877 James Malone NIFSTD:nlx_cell_20090201 These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#fibroblast VHOG:0001482 cell mouse embryonic fibroblast primary dermal fibroblast 分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。 分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。有分支过程的轮廓扁平，不规则；呈梭形或纺锤形。 原发性真皮成纤维细胞 在结缔组织中发现的大而扁平的椭圆形细胞，负责纤维的形成。 小鼠胚胎成纤维细胞 细胞 这些细胞可以是波形蛋白阳性，纤连蛋白阳性，fsp1阳性，MMP-1阳性，胶原I阳性，胶原III阳性和α-SMA阴性。 间充质来源的结缔组织细胞，分泌蛋白质，尤其是分子胶原蛋白，结缔组织的细胞外纤维状基质由其形成。 epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. BTO:0000414 CALOHA:TS-2026 CARO:0000077 FBbt:00000124 FMA:66768 WBbt:0003672 cell epitheliocyte squamous epithelial cell CALOHA:TS-1249 cell stratified epithelial cell cell circulating cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. cell mesenchymal stem cell mesenchymal stem cell 间充质干细胞 A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. BMSC BTO:0002625 BTO:0003298 CFU-F CL:0002452 FMA:70546 MSC Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. bone marrow stromal cells cell colony-forming unit-fibroblast marrow stromal cells mesenchymal precursor cell mesenchymal progenitor cells mesenchymal stem cell mesenchymal stromal cell mesenchymal stromal cells stem cells, mesenchymal A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. BMSC BTO:0002625 BTO:0003298 CFU-F CL:0002452 FMA:70546 MSC Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. bone marrow stromal cells cell colony-forming unit-fibroblast marrow stromal cells mesenchymal precursor cell mesenchymal progenitor cells mesenchymal stem cell mesenchymal stromal cell mesenchymal stromal cells stem cells, mesenchymal 一种结缔组织细胞，通常会产生被组织为三维团块的其他细胞。这种细胞类型是CD73阳性，CD90阳性，CD105阳性，CD45阴性，CD34阴性和MHCII阴性。它们可以在体外进一步分化成成骨细胞，脂肪细胞，肌细胞，神经元或成软骨细胞。最初被描述为居于骨髓，现在已知这种细胞类型存在于许多（如果不是全部的话）成人器官中。 干细胞，间充质 细胞 许多但不是所有的间充质细胞都来源于中胚层。据报道，MSC为CD3阴性、CD4阴性、CD5阴性、CD8阴性、CD11a阴性、CD11b阴性、CD14阴性、CD19阴性、CD29阳性、CD31阴性、CD34阴性、CD38阴性、CD40阴性、CD44阳性、CD45阴性、CD49阳性、CD54阳性、CD66b阴性、CD79a阴性、CD80阴性、CD102阳性、CD106阳性、CD117阳性、CD121a阳性、CD121b阳性、CD123阳性、CD124阳性、CD133阴性、CD146阳性、CD166阳性、CD271阳性、B220阴性、Gr1阴性、MHCI阳性、MHCII阴性、SSEA4阴性、sca1阳性、Ter119阴性和血型糖蛋白A阴性。培养的MSC能够产生干细胞因子IL7，IL8，IL11，TGF-β，丝切蛋白，半乳糖凝集素-1，层粘连蛋白受体1，亲环蛋白A和MMP-2。 间充质前体细胞 间充质基质细胞(mesenchymal stromal cell) 间充质基质细胞(mesenchymal stromal cells) 间充质干细胞 间充质祖细胞 集落形成单位 - 成纤维细胞 骨髓基质细胞(bone marrow stromal cells) 骨髓基质细胞(marrow stromal cells) motile cell motile cell 游动细胞 A cell that moves by its own activities. cell A cell that moves by its own activities. cell 细胞 通过自己的活动进行移动的细胞。 keratinizing barrier epithelial cell cell stratified squamous epithelial cell cell eukaryotic cell eukaryotic cell 真核细胞 cell cell 细胞 keratin accumulating cell cell keratinocyte An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. BTO:0000667 CALOHA:TS-0500 CL:0002185 FMA:62879 Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. cell keratinized cell of epidermis malpighian cell stuff accumulating cell A cell that is specialised to accumulate a particular substance(s). cell extraembryonic cell cell epidermal cell An epithelial cell of the integument (the outer layer of an organism). BTO:0001470 CALOHA:TS-0283 CL:1000396 FMA:62411 cell cell of epidermis epithelial cell of skin stromal cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. BTO:0002064 FMA:83624 cell skeletal muscle myoblast A myoblast that differentiates into skeletal muscle fibers. FMA:84799 cell skeletal myoblast animal cell animal cell 动物细胞 cell cell 细胞 experimentally modified cell in vitro experimentally modified cell in vitro 体外实验修饰细胞 A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12 cell experimentally modified cell in vitro A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12 cell experimentally modified cell in vitro 体外实验修饰细胞 细胞 经过一个深思熟虑和特定的实验过程而发生物理变化的细胞。 这个类已经被重新标记为仅仅涉及体外实验修饰的细胞，类似地，这个定义已经稍微更新以反映这一点。 “实验修饰的细胞”仅指体外细胞，而不是体内/环境细胞中的修饰。目前没有代表未经修饰的体外细胞的类别（除了亲代“体外细胞”）或代表修饰的天然细胞的类别。在ReO中可以找到更细化的实验修饰细胞亚类。 MHB 1.12.12 muscle precursor cell cell A non-terminally differentiated cell that is capable of developing into a muscle cell. somatic stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. CALOHA:TS-2086 FMA:63368 cell hematopoietic cell A cell of a hematopoietic lineage. BTO:0000574 CALOHA:TS-2017 FMA:70366 FMA:83598 cell haematopoietic cell haemopoietic cell hemopoietic cell cell in vitro cell in vitro 体外细胞 'In vitro', translating literally to 'in glass', typically refers to a controlled, often sterile, laboratory setting where cells or other specimens are placed by some agent for the purpose of studying or manipulating them as part of some research investigation. 'In vitro' is intended to contrast with 'native',which refers to cells or other biological entities that are found in a natural setting. It describes unicellular organisms removed from a natural environement and multicellular organism cells removed from an organism, or cells derived in culture from such displaced cells. 2012-01-12T09:58:38Z A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. cell haendel 'In vitro', translating literally to 'in glass', typically refers to a controlled, often sterile, laboratory setting where cells or other specimens are placed by some agent for the purpose of studying or manipulating them as part of some research investigation. 'In vitro' is intended to contrast with 'native',which refers to cells or other biological entities that are found in a natural setting. It describes unicellular organisms removed from a natural environement and multicellular organism cells removed from an organism, or cells derived in culture from such displaced cells. 2012-01-12T09:58:38Z A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. cell haendel 在受控人造环境中维持或繁殖的细胞，其用于调查。 在字面上翻译成“类中”的“体外”通常指的是受控的，通常是无菌的实验室环境，其中细胞或其他样本被某些机构放置以用于研究或操纵它们作为一些研究调查的一部分。 “体外”旨在与“天然”形成对比，“天然”是指在自然环境中发现的细胞或其他生物实体。它描述了从天然环境中除去的单细胞生物体和从生物体中除去的多细胞生物体细胞，或从这种置换的细胞培养中得到的细胞。 细胞 bone cell 2011-11-16T04:28:16Z A connective tissue cell found in bone. adiehl cell ecto-epithelial cell 2010-06-29T03:38:22Z An epithelial cell derived from ectoderm. FMA:69074 cell tmeehan bone marrow cell 2010-07-22T04:48:15Z A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. BTO:0004850 FMA:83621 MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. cell tmeehan general ecto-epithelial cell 2010-08-26T08:31:08Z Epithelial cells derived from general body ectoderm and ectoderm placodes. FMA:70556 cell tmeehan peripheral blood stem cell 2010-09-07T03:57:09Z A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). BTO:0002669 FMA:86711 PBSC cell tmeehan connective tissue cell connective tissue cell 结缔组织细胞 2010-09-15T03:01:54Z A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. CALOHA:TS-2096 CL:1000406 FMA:63875 cell tmeehan 2010-09-15T03:01:54Z A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. CALOHA:TS-2096 CL:1000406 FMA:63875 cell tmeehan 细胞 身体支持或骨架组织的细胞，主要由胚胎中胚层产生，包括脂肪组织，软骨和骨骼。 amniocyte 2010-09-20T10:13:37Z A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. BTO:0000066 cell tmeehan gestational hematopoietic stem cell 2010-09-22T09:05:13Z A hematopoietic stem cell that exists during embryogenesis. cell tmeehan somatic cell somatic cell 体细胞 2010-09-24T09:44:42Z A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). BTO:0001268 FMA:72300 WBbt:0008378 cell tmeehan 2010-09-24T09:44:42Z A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). BTO:0001268 FMA:72300 WBbt:0008378 cell tmeehan 不会将其遗传物质传递给生物体后代（即非生殖细胞系）的生物体细胞。 细胞 mesenchymal stem cell of the bone marrow 2011-02-28T01:47:47Z A mesenchymal stem cell that is part of the bone marrow. cell tmeehan fibroblast of dermis 2011-02-28T05:05:33Z cell tmeehan fibroblast of lung 2011-02-28T05:11:03Z A fibroblast that is part of lung. BTO:0000764 CALOHA:TS-0575 cell tmeehan skin fibroblast 2011-03-14T12:31:49Z A fibroblast of skin. BTO:0001255 CALOHA:TS-0935 cell tmeehan hematopoietic precursor cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. stromal cell of bone marrow GOC:cjm a stromal cell that is part_of a bone marrow bone marrow stromal cell precursor cell precursor cell 前体细胞 A cell that, by division or terminal differentiation, can give rise to other cell types. 通过分裂或末端分化，该细胞可以产生其他细胞类型。 A cell that, by division or terminal differentiation, can give rise to other cell types. Work is needed on GO '细胞分化'仍需要更多的工作才清楚是否等价类的定义'自然细胞'胜任一些'细胞分化'的工作。另外，可能需要考虑将其与非终末分化细胞合并。 Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. foreskin keratinocyte CALOHA:TS-0385 Keratinocyte from foreskin. foreskin fibroblast CALOHA:TS-0384 Fibroblast from foreskin. BJ fibroblast cord blood hematopoietic stem cell 2015-05-26T18:58:34Z Any hematopoietic stem cell that is part of a umbilical cord blood. CL:2000095 TermGenie cell disease of metabolism A disease that involving errors in metabolic processes of building or degradation of molecules. SNOMEDCT_US_2018_03_01:75934005 MESH:D008659 NCI:C3235 DOID:0014667 ICD10CM:E88.9 SNOMEDCT_US_2018_03_01:30390004 ICD9CM:277.9 metabolic disease disease_ontology UMLS_CUI:C0025517 carbohydrate metabolism disease An acquired metabolic disease that is characterized by abnormal carbohydrate metabolism. DOID:0050013 disease_ontology sensory system disease DOID:0050155 A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell). disease_ontology monogenic disease DOID:0050177 disease_ontology A genetic disease that is the result of one or more abnormal alleles and may be dominant (a single copy of the abnormal allele is sufficient to give rise to the disease), semi-dominant, or recessive (requiring both copies of the gene to have an abnormal allele). arrhythmogenic right ventricular cardiomyopathy UMLS_CUI:C0349788 arrhythmogenic right ventricular dysplasia/cardiomyopathy An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle. ORDO:217656 ARVC cardiomyopathy DOID:0050431 Xref MGI. OMIM mapping confirmed by DO. [SN]. arrhythmogenic right ventricular dysplasia MESH:D019571 ORDO:247 ARVD NCI:C84571 disease_ontology ARVC OMIM:PS107970 Danon disease GARD:9730 OMIM mapping confirmed by DO. [SN]. A lysosomal storage disease that is characterized by cardiomyopathy, skeletal myopathy and intellectual disability and has_material_basis_in mutations in the LAMP2 gene. OMIM:300257 DOID:0050437 disease_ontology ANTOPOL DISEASE MESH:D052120 NCI:C84735 UMLS_CUI:C0878677 PSEUDOGLYCOGENOSIS II Usher syndrome disease_ontology Xref MGI. OMIM mapping confirmed by DO. [LS]. UMLS_CUI:C0271097 NCI:C85217 ORDO:886 UMLS_CUI:C2931205 UMLS_CUI:C1568248 UMLS_CUI:C1568249 DOID:0050439 NCI:C126329 SNOMEDCT_US_2018_03_01:57838006 A syndrome characterized by a combination of hearing loss and visual impairment. MESH:D052245 OMIM:PS276900 SNOMEDCT_US_2018_03_01:73119000 Brugada syndrome sudden unexplained nocturnal death syndrome UMLS_CUI:C1721096 Dream disease ICD10CM:I49.8 A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. UMLS_CUI:C1142166 disease_ontology SUNDS Pokkuri death syndrome ORDO:130 MESH:D053840 Bangungut DOID:0050451 Brugada type idiopathic ventricular fibrillation OMIM mapping confirmed by DO. [SN]. congenital muscular dystrophy Xref MGI. OMIM mapping confirmed by DO. [SN]. GARD:9138 ICD9CM:359.0 OMIM:254100 A muscular dystrophy that is characterized by diminished muscle tone (hypotonia), progressive muscle weakness and degeneration (atrophy), abnormally fixed joints, spinal rigidity, and delays in reaching motor milestones such as sitting or standing unassisted. DOID:0050557 disease_ontology ORDO:97242 UMLS_CUI:C2937300 organ system cancer A cancer that is classified based on the organ it starts in. disease_ontology 2011-06-13T03:28:33Z snadendla MESH:D009371 DOID:0050686 cell type cancer disease_ontology A cancer that is classified by the type of cell from which it is derived. DOID:0050687 snadendla 2011-06-13T03:28:50Z cardiomyopathy NCI:C53654 NCI:C34830 SNOMEDCT_US_2018_03_01:20072003 SNOMEDCT_US_2018_03_01:89461002 Cardiomyopathies UMLS_CUI:C0036529 A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle. MESH:D009202 added from NeuroDevNet [WAK]. 2012-01-03T02:54:11Z ICD10CM:I42.9 MESH:D009202 UMLS_CUI:C0878544 SNOMEDCT_US_2018_03_01:57809008 UMLS_CUI:C0033141 SNOMEDCT_US_2018_03_01:89600009 SNOMEDCT_US_2018_03_01:85898001 disease_ontology ICD9CM:425 ICD10CM:I42 ICD10CM:I51.5 lschriml ICD9CM:425.9 DOID:0050700 electroclinical syndrome DOID:0050701 lschriml An epilepsy syndrome that is a group of clinical entities showing a cluster of electro-clinical characteristics, classified according to age at onset, cognitive and developmental antecedents and consequences, motor and sensory examinations, EEG features, provoking or triggering factors, and patterns of seizure occurrence with respect to sleep. electro-clinical syndrome disease_ontology 2012-04-11T11:42:46Z neonatal period electroclinical syndrome 2012-04-11T11:48:18Z disease_ontology lschriml JA:Epilepsy Genetics Kiel An electroclinical syndrome with onset in the neonatal period less than 44 weeks of gestational age. DOID:0050702 early infantile epileptic encephalopathy A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures. GARD:9255 2012-05-10T10:02:58Z DOID:0050709 OMIM:PS308350 ORDO:1934 disease_ontology Early Infantile Epileptic Encephalopathy with Burst-Suppression lschriml DOID:2481 X-linked monogenic disease A monogenic disease that has_material_basis_in muations in genes on the X chromosome. disease_ontology lschriml 2012-07-24T12:47:31Z DOID:0050735 autosomal dominant disease lschriml 2012-07-24T12:51:47Z DOID:0050736 disease_ontology An autosomal genetic disease that is characterized by the presence of one disease-associated mutation of a gene which is sufficient to cause the disease. autosomal recessive disease DOID:0050737 lschriml disease_ontology An autosomal genetic disease that is characterized by the presence of two mutated copies of the gene, both of which must be present in order for the disease or trait to develop. 2012-07-24T12:51:47Z autosomal genetic disease DOID:0050739 2012-07-24T04:45:53Z lschriml disease_ontology A monogenic disease that has_material_basis_in a mutation in a single gene on one of the non-sex chromosomes. Joubert syndrome DOID:0050777 ICD10CM:Q04.3 JBTS GARD:6802 2013-04-04T11:25:32Z OMIM:PS213300 A ciliopathy that is characterized by congenital malformation of the brainstem and agenesis or hypoplasia of the cerebellar vermis leading to an abnormal respiratory pattern, nystagmus, hypotonia, ataxia, and delay in achieving motor milestones. Xref MGI. lschriml ORDO:475 disease_ontology glomerulosclerosis A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney. DOID:0050851 lschriml disease_ontology 2014-04-15T03:40:31Z synucleinopathy DOID:0050890 alpha Synucleinopathies disease_ontology 2014-08-14T03:29:17Z A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. Synucleinopathies lschriml hereditary ataxia GARD:6614 A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements. lschriml disease_ontology 2015-10-05T14:38:17Z DOID:0050951 autoimmune disease of central nervous system DOID:0060004 disease_ontology An autoimmune hypersensitivity disease located_in the central nervous system. intrinsic cardiomyopathy A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause. disease_ontology DOID:0060036 developmental disorder of mental health disease_ontology DOID:0060037 A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development. specific developmental disorder DOID:0060038 A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination. disease_ontology pervasive developmental disorder DOID:1208 DOID:0060040 disease_ontology pervasive development disorder ICD9CM:299.80 A developmental disorder of mental health that refers to a group of five disorders characterized by impairments in socialization and communication, as well as restricted interests and repetitive behaviors. UMLS_CUI:C0154451 autism spectrum disorder GARD:10248 disease_ontology A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior. MESH:D000067877 DOID:0060041 hypersensitivity reaction disease disease_ontology DOID:0060056 An immune system disease that has_material_basis_in abnormal immune responses. sensory system cancer 2011-07-25T01:51:56Z DOID:0060116 A nervous system cancer that is located in the sensory system. disease_ontology lschriml pain agnosia DOID:0060145 disease_ontology An agnosia that is a loss of the ability to perceive and process pain. lschriml analgesia 2011-08-22T12:04:56Z acquired metabolic disease 2011-08-24T02:53:03Z A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption. DOID:0060158 disease_ontology lschriml ciliopathy disease_ontology emitraka 2015-05-21T10:41:29Z A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia. DOID:0060340 chromosomal deletion syndrome A chromosomal disease that has_material_basis_in partial deletion of chromosomes. elvira DOID:0060388 2015-09-28T15:48:41Z disease_ontology Kabuki syndrome 2015-11-18T16:21:35Z UMLS_CUI:C0796004 disease_ontology OMIM:300867 MESH:C537705 ORDO:2322 GARD:6810 A syndrome characterized by multiple congenital anomalies and mental retardation. Other characteristics include a peculiar facial gestalt, short stature, skeletal and visceral abnormalities, cardiac anomalies, and immunological defects. DOID:0060473 KMS Niikawa-Kuroki syndrome Kabuki make up syndrome OMIM:147920 elvira NCI:C124837 catecholaminergic polymorphic ventricular tachycardia DOID:0060674 ICD10CM:I47.2 A heart conduction disease characterized by adrenergically induced ventricular tachycardia manifesting as syncope and sudden death during exercise, stress or catecholamine infusion without the presence of structural cardiac abnormalities. ORDO:3286 OMIM:PS604772 disease_ontology Smith-Magenis syndrome 17p11.2 microdeletion syndrome GARD:8197 chromosome 17p11.2 deletion syndrome disease_ontology MESH:D058496 ICD10CM:Q93.5 A chromosome deletion syndrome characterized by mild-to-moderate infantile hypotonia, minor skeletal anomalies, prepubertal short stature, brachydactyly, ophthalmologic and otolaryngologic abnormalities, peripheral neuropathy, developmental delay, cognitive impairment, and behavioral abnormalities that has_material basis_in a 3.7-Mb interstitial deletion in chromosome 17p11.2 or sometimes by mutations in the RAI1 gene in the same region. ORDO:819 OMIM:182290 DOID:0060768 hypomyelinating leukodystrophy DOID:0060786 HLD A leukodystrophy characterized by T2 hyperintensity and T1 iso- or hyperintensity of affected white matter in the central nervous system. OMIM:PS312080 disease_ontology muscular disease DOID:0080000 disease_ontology A musculoskeletal system disease that affects the muscles. bone disease DOID:1290 skeletal disease UMLS_CUI:C0005940 SNOMEDCT_US_2018_03_01:76069003 disease_ontology MESH:D001847 ICD10CM:M89.9 DOID:0080001 A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function. bone remodeling disease A bone disease that results_in formation or resorption abnormalities located_in bone. DOID:0080005 disease_ontology X-linked dominant disease disease_ontology A X-linked monogenic disease that has_material_basis_in dominant inheritance. DOID:0080009 X-linked recessive disease disease_ontology A X-linked monogenic disease that has_material_basis_in recessive inheritance. DOID:0080012 chromosomal disease disease_ontology A genetic disease that has_material_basis_in extra, missing, or re-arranged chromosomes. DOID:0080014 myofibrillar myopathy 1 lschriml DOID:0110286 ICD10CM:G71.0 A myofibrillar myopathy that has_material_basis_in heterozygous, homozygous, or compound heterozygous mutation in the desmin gene on chromosome 2q35. DOID:0080092 ORDO:363543 2015-11-10T16:59:22Z disease_ontology autosomal recessive limb-girdle muscular dystrophy type 2R OMIM:601419 desminopathy myofibrillar myopathy DOID:0080307 GARD:10529 disease_ontology OMIM:PS601419 A myopathy that is characterized by slowly progressive muscle weakness that can involve both proximal muscles and distal muscles. polycystic kidney disease OMIM:PS173900 DOID:0080322 disease_ontology Dravet syndrome An early infantile epileptic encephalopathy that has_material_basis_in heterozygous mutation in the SCN1A gene on chromosome 2q24. DOID:0080422 OMIM:607208 disease_ontology GARD:10430 DOID:0060171 ORDO:33069 early infantile epileptic encephalopathy 6 congenital muscular dystrophy due to LMNA mutation ICD10CM:G71.2 A congenital muscular dystrophy characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the LMNA gene on chromosome 1q22. congenital muscular dystrophy LMNA-related disease_ontology L-CMD OMIM:613205 DOID:0110640 ORDO:157973 LMNA-related congenital muscular dystrophy long QT syndrome 1 GARD:3284 disease_ontology LQT1 OMIM:192500 ICD10CM:I45.8 DOID:0110644 A long QT syndrome that has_material_basis_in dominant inheritance of mutation in the KCNQ1 gene on chromosome 11p15.5-p15.4. ventricular fibrillation with prolonged QT interval neuronal ceroid lipofuscinosis 3 ORDO:228346 CLN3 ICD10CM:E75.4 A neuronal ceroid lipofuscinosis that is characterized by juvenile-onset of progressive dementia, seizures, and progressive visual failure and an ultrastructural pattern of lipopigment with a 'fingerprint' profile and has_material_basis_in homozygous or compound heterozygous mutation in the CLN3 gene on chromosome 16p11. GARD:5897 Batten disease OMIM:204200 disease_ontology juvenile neuronal ceroid lipofuscinosis DOID:0110731 DOID:0050756 autosomal recessive osteopetrosis 4 OPTB4 GARD:5993 disease_ontology An osteopetrosis characterized by autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the CLCN7 gene on chromosome 16p13. infantile malignant osteopetrosis 2 OMIM:611490 DOID:0110944 heart conduction disease disease_ontology DOID:10273 ICD9CM:426.6 UMLS_CUI:C0029630 heart rhythm disease A cardiovascular system disease that involves the heart's electrical conduction system. prostate cancer OMIM:300147 DOID:10283 Xref MGI. OMIM mapping confirmed by DO. [SN]. OMIM:300704 NCI2004_11_17:C7378 OMIM:601518 NCI:C7378 OMIM:611955 OMIM:611958 OMIM:611100 tumor of the prostate OMIM:611959 MESH:D011471 DOID:514 OMIM:609558 KEGG:05215 prostatic neoplasm OMIM:608658 ORDO:1331 OMIM:608656 NGP - new growth of prostate prostate cancer, familial OMIM:602759 ICD10CM:C61 OMIM:611868 SNOMEDCT_US_2018_03_01:93974005 prostate neoplasm disease_ontology hereditary prostate cancer prostatic cancer NCI2004_11_17:C3343 OMIM:610321 OMIM:609299 UMLS_CUI:C0033578 CSP2005:2016-2641 NCI:C3343 UMLS_CUI:C0376358 A male reproductive organ cancer that is located_in the prostate. OMIM:611928 malignant tumor of the prostate ICD9CM:185 OMIM:610997 OMIM:176807 prostate carcinoma MTH:612 UMLS_CUI:C0600139 KEGG:05215 EFO:0001663 carcinoma OF PROSTATE DOID:10286 cancer of prostate carcinoma of prostate A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. disease_ontology NCI:C4863 leukodystrophy DOID:10579 UMLS_CUI:C0023520 disease_ontology NCI:C61253 GARD:6895 ICD9CM:330.0 SNOMEDCT_US_2018_03_01:5101009 A cerebral degeneration characterized by dysfunction of the white matter of the brain. retinitis pigmentosa UMLS_CUI:C0220701 UMLS_CUI:C0035334 OMIM:PS268000 MESH:C538365 OMIM:268000 A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss. Xref MGI. OMIM mapping confirmed by DO. [LS]. ORDO:791 ICD10CM:H35.52 DOID:10584 pericentral pigmentary retinopathy NCI:C85045 MESH:D012174 disease_ontology DOID:14742 SNOMEDCT_US_2018_03_01:28835009 GARD:5694 Alzheimer's disease Alzheimer disease Xref MGI. OMIM mapping confirmed by DO. [SN]. CSP2005:0485-6737 MESH:D000544 GARD:10254 SNOMEDCT_US_2018_03_01:73768007 SNOMEDCT_US_2018_03_01:26929004 ICD9CM:331.0 UMLS_CUI:C0002395 EFO:0000249 ICD10CM:G30.9 A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. DOID:10652 Alzheimers dementia NCI:C2866 disease_ontology ICD10CM:G30 KEGG:05010 age related macular degeneration Age Related Maculopathies NCI:C84391 DOID:10871 disease_ontology Senile macular retinal degeneration A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision. UMLS_CUI:C0242383 OMIM:PS603075 SNOMEDCT_US_2018_03_01:18222007 ICD9CM:362.50 Age Related Maculopathy Senile macular degeneration MESH:D008268 OMIM mapping confirmed by DO. [SN]. EFO:0001365 age-related macular degeneration ICD10CM:H35.30 obsessive-compulsive disorder disease_ontology DOID:10933 MTHICD9_2006:300.3 UMLS_CUI:C0028768 Anancastic neurosis SNOMEDCT_US_2018_03_01:71478004 ICD9CM:300.3 MESH:D009771 ICD10CM:F42 NCI:C88411 obsessive compulsive disorder ICD10CM:F42.9 ICD10CM:F42.8 An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions). nephritis MESH:D009393 A kidney disease that is characterized by an inflammation of the kidneys. SNOMEDCT_US_2018_03_01:52845002 disease_ontology DOID:10952 ICD10CM:N05 UMLS_CUI:C0027697 ICD10CM:N08 NCI:C26833 Alport syndrome NCI2004_11_17:C34842 disease_ontology SNOMEDCT_US_2018_03_01:57333009 UMLS_CUI:C0027706 A monogenic disease that is characterized by glomerulonephritis, endstage kidney disease, and hearing loss. MESH:D009394 ORDO:63 OMIM mapping confirmed by DO. [SN]. DOID:10983 Hereditary Nephritis GARD:5785 heart disease A cardiovascular system disease that involves the heart. DOID:114 MESH:D006331 NCI:C3079 ICD10CM:I51.9 SNOMEDCT_US_2018_03_01:56265001 ICD9CM:429.9 disease_ontology UMLS_CUI:C0018799 myotonic dystrophy type 1 SNOMEDCT_US_2018_03_01:77956009 UMLS_CUI:C0027126 DOID:11722 GARD:8310 A myotonic disease that is characterized by progressive muscle wasting and weakness affecting the distal skeletal and smooth muscles of lower legs, hands, neck, and face along with myotonia and cataracts and has_material_basis_in the autosomal dominant inheritance of the DMPK gene containing an expansion of a CTG trinucleotide repeat in the non-coding region. OMIM mapping confirmed by DO. [SN]. MESH:D009223 myotonic dystrophy of Steinert congenital myotonic dystrophy NCI:C84914 Steinert disease ICD10CM:G71.11 disease_ontology ICD9CM:359.21 OMIM:160900 Dystrophia myotonica Duchenne muscular dystrophy MTHICD9_2006:359.1 A muscular dystrophy that has material basis in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy. OMIM mapping confirmed by DO. [SN]. DOID:11723 SNOMEDCT_US_2018_03_01:76670001 NCI:C75482 OMIM:310200 Muscular dystrophy, Duchenne GARD:6291 UMLS_CUI:C0013264 MESH:D020388 disease_ontology limb-girdle muscular dystrophy UMLS_CUI:C0686353 Xref MGI. OMIM mapping confirmed by DO. [SN]. NCI:C84828 limb girdle muscular dystrophy GARD:6907 MESH:D049288 A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles. DOID:11724 ORDO:263 CSP2005:1849-6662 SNOMEDCT_US_2018_03_01:56096001 Erb's muscular dystrophy ICD10CM:G71.0 disease_ontology SNOMEDCT_US_2018_03_01:93153005 Leyden-Mbius muscular dystrophy hypertrophic cardiomyopathy NCI:C84773 hypertrophic obstructive cardiomyopathy Xref MGI. OMIM mapping confirmed by DO. [SN]. DOID:11986 KEGG:05410 disease_ontology ORDO:217568 ICD9CM:425.1 MESH:D002312 UMLS_CUI:C0949658 SNOMEDCT_US_2018_03_01:15471000 ICD10CM:I42.1 MESH:D024741 UMLS_CUI:C0007194 NCI:C34449 SNOMEDCT_US_2018_03_01:45227007 An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause. DOID:11984 SNOMEDCT_US_2018_03_01:83978005 ICD9CM:425.11 familial hypertrophic cardiomyopathy aplastic anemia disease_ontology GARD:5836 MESH:D000741 SNOMEDCT_US_2018_03_01:79000000 ICD9CM:284.9 NCI:C2870 An anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow. OMIM:609135 ICD10CM:D61.9 UMLS_CUI:C0002874 OMIM mapping confirmed by DO. [SN]. DOID:12449 autistic disorder SNOMEDCT_US_2018_03_01:34883005 DOID:12849 infantile autism EFO:0003758 Kanner's syndrome NCI:C97161 MESH:D001321 ORDO:106 SNOMEDCT_US_2018_03_01:43614003 MTHICD9_2006:299.0 disease_ontology UMLS_CUI:C0004352 ICD10CM:F84.0 autism An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years. SNOMEDCT_US_2018_03_01:38763009 autistic disorder of childhood onset childhood autism ICD9CM:299.0 Xref MGI. OMIM mapping confirmed by DO. [SN]. OMIM:209850 Huntington's disease ICD10CM:G10 KEGG:05016 MESH:D006816 ICD9CM:333.4 HD GARD:6677 disease_ontology NCI:C82342 ICD9CM_2006:333.4 DOID:12858 OMIM:143100 UMLS_CUI:C0020179 CSP2005:2057-3283 Huntington disease SNOMEDCT_US_2018_03_01:58756001 A neurodegenerative disease that has material basis in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has material basis in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities. Huntington's chorea cardiovascular system disease A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. ICD9CM:429.2 disease_ontology MESH:D002318 UMLS_CUI:C0007222 NCI:C2931 DOID:73 SNOMEDCT_US_2018_03_01:49601007 DOID:1287 disease of subdivision of hemolymphoid system neurodegenerative disease UMLS_CUI:C0524851 UMLS_CUI:C1285162 DOID:4874 ICD10CM:G31.9 A central nervous system disease that results in the progressive deterioration of function or structure of neurons. DOID:1289 disease_ontology NCI:C27090 Neurodegenerative disease degenerative disease NCI2004_11_17:C4802 MESH:D019636 dementia UMLS_CUI:C0154319 ICD9CM:290.8 A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior. disease_ontology MESH:D003704 DOID:1307 focal segmental glomerulosclerosis NCI:C37308 FGS CSP2005:4003-0020 EFO:0004236 FSGS GARD:6517 OMIM:PS603278 SNOMEDCT_US_2018_03_01:25821008 UMLS_CUI:C0017668 disease_ontology Xref MGI. OMIM mapping confirmed by DO. [SN]. DOID:1312 MESH:D005923 focal glomerular sclerosis DOID:3945 focal glomerulosclerosis congenital hypoplastic anemia ICD10CM:D61.01 DOID:1342 UMLS_CUI:C0702159 UMLS_CUI:C0949116 SNOMEDCT_US_2018_03_01:88854002 CSP2005:0427-0659 MESH:D029502 congenital aplastic anemia ICD10CM:D61.0 disease_ontology ICD9CM:284.0 SNOMEDCT_US_2018_03_01:28975000 DOID:13639 Constitutional aplastic anaemia osteopetrosis NCI:C26840 SNOMEDCT_US_2018_03_01:63941000 marble bone Albers-Schonberg disease GARD:4155 ORDO:667 OMIM:PS259700 ICD9CM:756.52 disease_ontology CSP2005:1849-7232 An osteosclerosis that has_material_basis_in lack of bone resorption which results_in abnormally hard and brittle bones. UMLS_CUI:C0029454 Xref MGI. OMIM mapping submitted by NeuroDevNet. [LS]. MESH:D010022 DOID:13533 ICD10CM:Q78.2 OMIM:PS607634 SNOMEDCT_US_2018_03_01:1926006 Fanconi anemia disease_ontology UMLS_CUI:C0015625 Fanconi panmyelopathy SNOMEDCT_US_2018_03_01:30575002 Fanconi pancytopenia OMIM:PS227650 DOID:13636 MESH:D005199 ORDO:84 Fanconi's anemia GARD:6425 ICD10CM:D61.09 NCI:C62505 Xref MGI. OMIM mapping confirmed by DO. [SN]. OMIM mapping by NeuroDevNet. [LS]. A congenital hypoplastic anemia characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. It is a result of a genetic defect in a cluster of proteins responsible for DNA repair. CADASIL ORDO:136 UMLS_CUI:C0751587 DOID:13945 hereditary multi-infarct dementia OMIM:600142 cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy NCI:C84606 A leukodystrophy characterized by recurrent subcortical ischemic stroke and cognitive impairment. GARD:1049 disease_ontology MESH:D046589 OMIM:PS125310 Down syndrome Downs syndrome disease_ontology MTHICD9_2006:758.0 Down's syndrome - trisomy 21 MESH:D004314 DOID:14250 NCI:C2993 OMIM:190685 ICD10CM:Q90.9 trisomy 21 syndrome G Trisomy NCI2004_11_17:C2993 Complete trisomy 21 syndrome A chromosomal disease that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability. UMLS_CUI:C0013080 GARD:10247 CSP2005:1254-8068 OMIM mapping confirmed by DO. [SN]. Down's syndrome ICD10CM:Q90 ICD9CM:758.0 SNOMEDCT_US_2018_03_01:41040004 fragile X syndrome MARKER X SYNDROME disease_ontology MARTIN-BELL SYNDROME A X-linked dominant disease that is characterized by moderate to severe mental retardation, macroorchidism, and distinct facial features, including long face, large ears, and prominent jaw, and has material basis in X-linked inheritance and a loss of FMR1 function. OMIM:300624 MESH:D005600 OMIM mapping confirmed by DO. [SN]. DOID:14261 ORDO:908 ICD9CM:759.83 UMLS_CUI:C0016667 ICD10CM:Q99.2 NCI:C84717 FRAGILE X MENTAL RETARDATION SYNDROME GARD:6464 SNOMEDCT_US_2018_03_01:613003 Marfan syndrome ICD10CM:Q87.40 disease_ontology ICD9CM:759.82 SNOMEDCT_US_2018_03_01:19346006 OMIM:154700 Marfan's syndrome UMLS_CUI:C0024796 GARD:6975 NCI:C34807 OMIM mapping confirmed by DO. [SN]. MESH:D008382 ICD10CM:Q87.4 DOID:14323 A connective tissue disease that is characterized by tall stature, elongated extremities, mitral valve prolapse, aortic dilatation, aortic dissection, and subluxation of the lens. Parkinson's disease ICD9CM:332.0 Xref MGI. OMIM mapping confirmed by DO. [SN]. ICD10CM:G20 ICD9CM:332 NCI:C26845 paralysis agitans DOID:14330 KEGG:05012 Parkinson disease UMLS_CUI:C0030567 SNOMEDCT_US_2018_03_01:49049000 MESH:D010300 A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. OMIM:PS168600 EFO:0002508 disease_ontology CSP2005:2057-3689 GARD:10251 ORDO:2828 Machado-Joseph disease DOID:1440 UMLS_CUI:C0024408 OMIM mapping confirmed by DO. [SN]. Azorean disease SNOMEDCT_US_2018_03_01:91952008 NCI:C84830 An autosomal dominant cerebellar ataxia that is characterized by slow degeneration of the hindbrain and has_material_basis_in expansion of CAG triplet repeats (glutamine) in the ATXN3 gene. MJD spinocerebellar ataxia type 3 MESH:D017827 disease_ontology OMIM:109150 spinocerebellar ataxia 3 autosomal dominant cerebellar ataxia DOID:2478 spinocerebellar ataxia UMLS_CUI:C0087012 MESH:D020754 NCI:C82341 A hereditary ataxia that has_material_basis_in autosomal dominant inheritance. DOID:1441 disease_ontology cerebral degeneration Brain degeneration UMLS_CUI:C0154671 disease_ontology SNOMEDCT_US_2018_03_01:73768007 ICD9CM:331.9 DOID:1443 SNOMEDCT_US_2018_03_01:52522001 GARD:6019 A brain disease that is characterized by loss of structure or function of neurons, including death of neurons and loss of brain tissue. neuronal ceroid lipofuscinosis ICD10CM:E75.4 ORDO:79262 NCI:C61257 disease_ontology GARD:10739 Xref MGI. OMIM mapping submitted by NeuroDevNet. [LS]. UMLS_CUI:C0027877 ORDO:216 OMIM:PS256730 CSP2005:1849-6833 DOID:14503 MESH:D009472 SNOMEDCT_US_2018_03_01:42012007 hereditary ceroid lipofuscinosis disease of cellular proliferation DOID:14566 disease_ontology DOID:0000818 neoplasm A disease that is characterized by abnormally rapid cell division. cell process disease major depressive disorder ICD9CM:296.2 DOID:2240 DOID:2241 DOID:1470 single major depressive episode ICD10CM:F32 ICD9CM:296.20 Xref MGI. ICD9CM:296.3 ICD10CM:F33 ICD10CM:F33.9 NCI:C34796 OMIM:608691 SNOMEDCT_US_2018_03_01:36923009 UMLS_CUI:C0154409 SNOMEDCT_US_2018_03_01:66344007 ICD10CM:F32.9 disease_ontology An endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities. OMIM:608520 UMLS_CUI:C0024517 DOID:7580 DOID:10614 ICD9CM:296.30 recurrent major depression cystic fibrosis An autosomal recessive disease that is characterized by the buildup of thick, sticky mucus that can damage many organs. ICD10CM:E84.9 NCI:C2975 DOID:1485 UMLS_CUI:C0010674 DOID:1484 OMIM:219700 MESH:D003550 OMIM mapping confirmed by DO. [SN]. mucoviscidosis DOID:12447 SNOMEDCT_US_2018_03_01:85809002 ICD9CM:277.0 ICD10CM:E84 disease_ontology DOID:13383 DOID:14395 GARD:6233 CF eye and adnexa disease disease_ontology SNOMEDCT_US_2018_03_01:31411005 ICD10CM:H35.00 SNOMEDCT_US_2018_03_01:42873008 A sensory system disease that is located_in the eye or the adnexa of the eye. UMLS_CUI:C0004608 ICD9CM:362.10 DOID:1492 reproductive system disease genital system disease DOID:6309 disease_ontology UMLS_CUI:C1335037 NCI:C27613 A disease of anatomical entity that is located_in reproductive system organs. DOID:15 disease of mental health ICD10CM:F99-F99 UMLS_CUI:C0004936 A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture. MESH:D001523 NCI:C2893 SNOMEDCT_US_2018_03_01:74732009 ICD10CM:F99 disease_ontology DOID:150 cognitive disorder A disease of mental health that affects cognitive functions including memory processing, perception and problem solving. cognitive disease disease_ontology NCI:C34870 MESH:D019965 NCI2004_11_17:C34870 Organic Mental disorder DOID:1561 UMLS_CUI:C0029227 ICD10CM:F09 endogenous depression NCI:C34532 UMLS_CUI:C0041696 clinical depression disease_ontology unipolar depression UMLS_CUI:C0011573 DOID:6340 A mental depression that is characterized by a dysregulation of the endogenous opioid system and not of the monaminergic system. OMIM:608516 EFO:0003761 MESH:D003866 OMIM mapping confirmed by DO. [LS]. DOID:1595 CSP2005:2483-6681 NCI:C35094 mental depression ICD10CM:F33.9 ICD10CM:F32.9 disease_ontology NCI:C2982 DOID:14672 SNOMEDCT_US_2018_03_01:41006004 UMLS_CUI:C0011570 MESH:D003863 DOID:1596 integumentary system disease DOID:16 A disease of anatomical entity that is located_in the integumentary system comprising the skin and its appendages. disease_ontology cancer primary cancer MESH:D009369 Updating out dated UMLS CUI. ICD9CM:199 stedman:rlc SNOMEDCT_US_2018_03_01:38807002 malignant neoplasm A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis. ICD10CM:C80.1 DOID:162 UMLS_CUI:C0006826 malignant tumor disease_ontology ICD10CM:C80 NCI:C9305 musculoskeletal system disease DOID:17 disease_ontology SNOMEDCT_US_2018_03_01:928000 A disease of anatomical entity that occurs in the muscular and/or skeletal system. MESH:D009140 NCI:C107377 UMLS_CUI:C0026857 vascular disease MESH:D014652 NCI:C26693 ICD9CM:442.9 SNOMEDCT_US_2018_03_01:85659009 DOID:324 DOID:325 UMLS_CUI:C0752127 MESH:D000783 UMLS_CUI:C0042373 vascular tissue disease A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart. MESH:D020758 SNOMEDCT_US_2018_03_01:27550009 UMLS_CUI:C0752130 ICD10CM:I72.9 DOID:0000405 UMLS_CUI:C0002940 NCI:C35117 DOID:45 DOID:2869 disease_ontology DOID:178 DOID:2403 MESH:D020760 urinary system disease A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra. disease_ontology Non-neoplastic urinary tract disease NCI2004_11_17:C27599 DOID:18 NCI:C27599 DOID:579 urinary tract disease UMLS_CUI:C1335051 epilepsy A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. ICD9CM:345.9 EFO:0000474 UMLS_CUI:C0014544 disease_ontology MESH:D004827 ICD10CM:G40.9 DOID:1826 ICD10CM:G40.909 SNOMEDCT_US_2018_03_01:84757009 epileptic syndrome epilepsy syndrome NCI:C3020 Gaucher's disease GARD:8233 ORDO:355 SNOMEDCT_US_2018_03_01:62201009 glucosylceramide beta-glucosidase deficiency Xref MGI. OMIM mapping confirmed by DO. [SN]. NCI:C61268 DOID:1926 UMLS_CUI:C0017205 disease_ontology kerasin thesaurismosis Gaucher disease glocucerebrosidase deficiency MESH:D005776 acid beta-glucosidase deficiency A sphingolipidosis characterized by deficiency of the enzyme glucocerebrosidase which results in the accumulation of harmful quantities of the glycolipid glucocerebroside throughout the body, especially within the bone marrow, spleen and liver. SNOMEDCT_US_2018_03_01:2859005 ICD10CM:E75.22 sphingolipidosis ICD10CM:E75.3 UMLS_CUI:C0037899 NCI:C117254 MESH:D013106 DOID:1927 SNOMEDCT_US_2018_03_01:58459009 A lipid storage disease characterized by functional deficiencies in the enzymes needed for lysosomal degradation of sphingolipid substrates. Sphingolipidosis disease_ontology sphingolipidoses GARD:7672 reproductive organ cancer UMLS_CUI:C0178830 DOID:193 NCI2004_11_17:C3674 disease_ontology DOID:1900 NCI:C3674 Reproductive tumor cancer of reproductive system An organ system cancer that is manifested in the reproductive organs. malignant reproductive system neoplasm Rubinstein-Taybi syndrome OMIM:180849 An autosomal dominant disease characterized by short stature, moderate to sever intellectual disability, distinctive facial features and broad thumbs and first toes; additionally it can include eye abnormalities, heart and kidney defects, dental problems and obesity. Xref MGI. OMIM mapping confirmed by DO. [SN]. Rubinstein syndrome MESH:D012415 SNOMEDCT_US_2018_03_01:45582004 ICD10CM:Q87.2 OMIM:610543 DOID:1933 NCI:C75466 UMLS_CUI:C0035934 disease_ontology Broad Thumb-Hallux syndrome OMIM:613684 proximal chromosome 16p13.3 deletion syndrome ORDO:783 GARD:7593 Bardet-Biedl syndrome NCI:C118632 disease_ontology ORDO:110 UMLS_CUI:C0752166 An autosomal recessive disease that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases. OMIM mapping confirmed by DO. [SN]. ICD10CM:Q87.89 SNOMEDCT_US_2018_03_01:5619004 MESH:D020788 OMIM:PS209900 DOID:1935 GARD:6866 degeneration of macula and posterior pole degeneration of macula or posterior pole degeneration of macula and posterior pole of retina ICD9CM_2006:362.5 ICD10CM:H35.3 ICD9CM:362.5 UMLS_CUI:C0339436 disease_ontology DOID:2007 anxiety disorder SNOMEDCT_US_2018_03_01:65673007 MESH:D001008 disease_ontology DOID:12884 anxiety NCI:C2878 anxiety state ICD10CM:F41.9 A cognitive disorder that involves an excessive, irrational dread of everyday situations. OMIM:607834 DOID:2030 UMLS_CUI:C0003469 communication disorder A specific developmental disorder that involves specific developmental disorders of speech and language. SNOMEDCT_US_2018_03_01:74825008 MESH:D003147 DOID:2033 ICD10CM:F80.9 disease_ontology NCI:C2958 UMLS_CUI:C0009460 ocular cancer UMLS_CUI:C0153632 eye neoplasm ICD9CM:190.8 Ocular tumor malignant eye neoplasm UMLS_CUI:C0015414 neoplasm of eye proper DOID:9985 neoplasm of eye disease_ontology NCI2004_11_17:C3030 DOID:2174 NCI:C3030 MESH:D005134 A sensory system cancer located_in the eye that is characterized by uncontrolled cellular proliferation in the eye. CSP2005:2018-3273 syndrome disease_ontology MESH:D013577 A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality. SNOMEDCT_US_2018_03_01:64572001 UMLS_CUI:C0039082 NCI:C28193 DOID:225 motor neuron disease UMLS_CUI:C0085084 disease_ontology ICD10CM:G12.20 ICD10CM:G12.2 ICD9CM:335.2 DOID:231 MESH:D016472 A neurodegenerative disease that is located_in the motor neurones. SNOMEDCT_US_2018_03_01:37340000 anemia anaemia UMLS_CUI:C0002871 ICD9CM:285.9 NCI:C2869 PRISM. DOID:2355 MESH:D000740 ICD10CM:D64.9 EFO:0004272 SNOMEDCT_US_2018_03_01:64593003 A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells. disease_ontology gangliosidosis MESH:D005733 UMLS_CUI:C0017083 disease_ontology ORDO:309144 DOID:2368 A sphingolipidosis that is characterized by the accumulation of lipids known as gangliosides. SNOMEDCT_US_2018_03_01:50967008 ICD10CM:E75.10 GARD:12510 multiple sclerosis SNOMEDCT_US_2018_03_01:24700007 A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. EFO:0003885 MESH:D009103 CSP2005:2042-2324 GARD:10255 OMIM mapping confirmed by DO. [LS]. DOID:2377 NCI:C3243 ICD10CM:G35 ICD9CM:340 Generalized multiple sclerosis UMLS_CUI:C0026769 OMIM:612596 disease_ontology OMIM:612595 OMIM:612594 insular sclerosis psychotic disorder ICD9CM:298.8 DOID:2468 EFO:0000677 A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality. mental or behavioural disorder disease_ontology UMLS_CUI:C0029516 prostate adenocarcinoma UMLS_CUI:C0007112 DOID:2526 A prostate carcinoma that derives_from epithelial cells of glandular origin. NCI:C2919 disease_ontology dermatitis disease_ontology skin inflammation DOID:8614 eczema SNOMEDCT_US_2018_03_01:4979002 DOID:8917 DOID:2723 SNOMEDCT_US_2018_03_01:43116000 NCI:C2983 ICD10CM:L30.9 MESH:D003872 A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin. UMLS_CUI:C0011603 epidermolysis bullosa UMLS_CUI:C0014527 Epidermolysis bullosa A vesiculobullous skin disease that is characterized by formation of blisters with only minor skin trauma, which can cause widespread wounds, dehydration, electrolyte abnormalities, and severe infection, frequently develops_from mutations in connective tissue elements, including genes encoding keratin, collagen, and laminin. DOID:2730 disease_ontology acantholysis bullosa ICD10CM:Q81 GARD:6359 ICD10CM:Q81.9 NCI:C67383 MESH:D004820 SNOMEDCT_US_2018_03_01:61003004 CSP2005:0726-9169 vesiculobullous skin disease UMLS_CUI:C0037275 A skin disease that is characterized by fluid filled blisters. disease_ontology MESH:D012872 DOID:2731 long QT syndrome ORDO:101016 NCI:C34786 OMIM:PS192500 SNOMEDCT_US_2018_03_01:9651007 ORDO:768 ICD9CM:426.82 MESH:D029597 GARD:6922 An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles). CSP2005:4009-0053 DOID:2843 ICD10CM:I45.81 disease_ontology SNOMEDCT_US_2018_03_01:20852007 UMLS_CUI:C0035828 long Q-T syndrome DOID:4069 Romano-Ward syndrome OMIM mapping confirmed by DO. [SN]. NCI:C85049 MESH:D008133 UMLS_CUI:C0023976 LQT immune system disease ICD10CM:D89.9 ICD9CM:279 UMLS_CUI:C0041806 ICD9CM:279.9 DOID:2914 disease_ontology A disease of anatomical entity that is located_in the immune system. EFO:0000540 glomerulonephritis NCI:C26784 UMLS_CUI:C0017658 GARD:6516 ICD10CM:N05 ICD10CM:N08 SNOMEDCT_US_2018_03_01:36171008 DOID:2921 disease_ontology sn:IEDB A nephritis that causes inflammation of the glomeruli located_in kidney. MESH:D005921 cystic kidney disease DOID:2975 disease_ontology renal Cyst UMLS_CUI:C0022679 NCI2004_11_17:C3970 MTH:646 MESH:D052177 adenocarcinoma DOID:299 disease_ontology NCI:C2852 SNOMEDCT_US_2018_03_01:35917007 UMLS_CUI:C0001418 adenocarcinomas MESH:D000230 A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue. carcinoma CSP2005:2000-5801 UMLS_CUI:C0007097 UMLS_CUI:C1368683 A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. disease_ontology SNOMEDCT_US_2018_03_01:68453008 malignant Epithelioma NCI:C3709 DOID:6570 NCI:C2916 MESH:D009375 DOID:2428 MESH:D002277 epithelioma SNOMEDCT_US_2018_03_01:71298006 DOID:305 UMLS_CUI:C0553707 NCI2004_11_17:C6927 nervous system cancer UMLS_CUI:C0153643 DOID:3093 neural tumor UMLS_CUI:C0027665 MESH:D009380 nervous system neoplasm NCI2004_11_17:C35562 neoplasm of nervous system tumor of the nervous system ICD9CM:192.9 DOID:1193 DOID:3195 ICD9CM:192 CSP2005:2012-5157 NCI2004_11_17:C3268 NCI:C35562 disease_ontology An organ system cancer located_in the nervous system that affects the central or peripheral nervous system. DOID:4695 UMLS_CUI:C1334956 malignant neoplasm of nervous system neural neoplasm Pelizaeus-Merzbacher disease Pelizaeus Merzbacher brain sclerosis disease_ontology OMIM:312080 MTHICD9_2006:330.0 MESH:D020371 hypomyelinating leukodystrophy 1 sudanophilic leukodystrophy, Paelizeus-Merzbacher type PMD NCI:C75487 SNOMEDCT_US_2018_03_01:64855000 DOID:3210 Pelizaeus-Merzbacher brain sclerosis diffuse familial brain sclerosis CSP2005:1849-5479 HLD1 A hypomyelinating leukodystrophy characterized by impaired myelin formation, nystagmus, spastic quadriplegia, ataxia, and developmental delay that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22. UMLS_CUI:C0205711 ORDO:702 Leukodystrophy, sudanophilic GARD:4265 lysosomal storage disease UMLS_CUI:C0085078 MESH:D016464 disease_ontology inborn lysosomal enzyme disorder lysosomal storage metabolism disorder DOID:3211 SNOMEDCT_US_2018_03_01:23585005 NCI:C61250 An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function. disorder of lysosomal enzyme CSP2005:1849-5878 demyelinating disease UMLS_CUI:C0011303 disease_ontology demyelinating disorder DOID:3213 NCI:C34527 MESH:D003711 NCI2004_11_17:C34527 central nervous system disease MESH:D002493 UMLS_CUI:C0007682 disease_ontology NCI:C2934 A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system. ICD10CM:G96.9 DOID:331 SNOMEDCT_US_2018_03_01:23853001 atopic dermatitis atopic eczema OMIM:PS603165 allergic dermatitis Allergic Atopic neurodermatitis Xref MGI. OMIM mapping confirmed by DO. [SN]. SNOMEDCT_US_2018_03_01:24079001 Besnier's prurigo A dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking. Atopic dermatitis EFO:0000274 UMLS_CUI:C0011615 OMIM:603165 ls:IEDB disease_ontology ICD10CM:L20 ICD10CM:L20.9 ICD10CM:L20.81 MESH:D003876 DOID:3310 bipolar disorder disease_ontology EFO:0000289 bipolar disorder manic phase NCI2004_11_17:C34423 ICD9CM:296.60 ICD10CM:F31 Manic Bipolar Affective disorder ICD9CM:296.40 ICD9CM:296.80 CSP2005:2483-6691 Depressive-manic psych. NCI:C34805 bipolar depression UMLS_CUI:C0005587 SNOMEDCT_US_2018_03_01:13746004 UMLS_CUI:C0005586 NCI:C34423 NCI:C34424 NCI2004_11_17:C34805 manic disorder DOID:3311 UMLS_CUI:C0236780 DOID:9554 DOID:9555 mixed bipolar disorder Manic bipolar I disorder A mood disorder that involves alternating periods of mania and depression. DOID:3312 UMLS_CUI:C0024713 CSP2005:2483-6684 ICD10CM:F31.9 SNOMEDCT_US_2018_03_01:68569003 Manic Depressive disorder SNOMEDCT_US_2018_03_01:16506000 MESH:D001714 manic depression amyotrophic lateral sclerosis ORDO:803 UMLS_CUI:C0002736 ICD10CM:G12.21 Lou Gehrig's disease motor neuron disease, bulbar DOID:332 disease_ontology OMIM:PS105400 MTHICD9_2006:335.20 KEGG:05014 ALS ICD9CM:335.20 EFO:0000253 NCI2004_11_17:C34373 MESH:D000690 NCI:C34373 A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. SNOMEDCT_US_2018_03_01:86044005 Tay-Sachs disease MTHICD9_2006:330.1 NCI:C85184 GM2 gangliosidosis, type 1 MESH:D013661 GARD:7737 DOID:3320 A GM2 gangliosidosis that is characterized the onset in infancy of developmental retardation, followed by paralysis, dementia and blindness, with death in the second or third year of life and has_material_basis_in homozygous or compound heterozygous mutation in the alpha subunit of the hexosaminidase A gene (HEXA) on chromosome 15q23. UMLS_CUI:C0039373 OMIM mapping confirmed by DO. [SN]. disease_ontology hexosaminidase A deficiency CSP2005:1849-8690 OMIM:272800 ICD10CM:E75.02 GM2 gangliosidosis A gangliosidosis that is characterized by excessive accumulation of ganglioside GM2 and related glycolipids in the lysosomes. ICD10CM:E75.0 ICD10CM:E75.00 UMLS_CUI:C0268274 disease_ontology gangliosidosis GM2 DOID:3321 MESH:D020143 SNOMEDCT_US_2018_03_01:33316007 mood disorder SNOMEDCT_US_2018_03_01:74421008 MESH:D019964 SNOMEDCT_US_2018_03_01:46206005 ICD10CM:F39 DOID:3324 UMLS_CUI:C0525045 disease_ontology episodic mood disorder Updating outdated UMLS CUI. A cognitive disorder that involves a disturbance in mood as the predominant underlying feature. EFO:0004247 ICD10CM:F30-F39 NCI:C92200 peripheral vascular disease SNOMEDCT_US_2018_03_01:2929001 DOID:2868 DOID:341 A vascular disease that is characterized by obstruction of larger arteries not within the coronary, aortic arch vasculature, or brain. arterial occlusive disease UMLS_CUI:C0003838 MESH:D016491 UMLS_CUI:C0031115 disease_ontology ICD9CM:443.81 skin disease Genodermatosis DOID:187 disease_ontology SNOMEDCT_US_2018_03_01:95320005 ICD9CM:702 DOID:6486 DOID:37 MESH:D012873 MESH:D012871 UMLS_CUI:C0029574 DOID:1698 An integumentary system disease that is located_in skin. DOID:1576 NCI:C3371 DOID:8948 skin and subcutaneous tissue disease SNOMEDCT_US_2018_03_01:5613003 SNOMEDCT_US_2018_03_01:80659006 UMLS_CUI:C0037277 UMLS_CUI:C0037274 NCI:C27554 male reproductive organ cancer MESH:D005834 NCI:C3054 disease_ontology ICD10CM:C60-C63 NCI2004_11_17:C3054 ICD10CM:C63.9 DOID:10284 CSP2005:2016-2462 NCI:C8561 malignant neoplasm of male genital organ neoplasm of male genital organ malignant tumor of male genital organ NCI2004_11_17:C8561 malignant neoplasm of male genital organs tumor of male Reproductive system ICD9CM:187.9 malignant neoplasm of male genital organ or tract SNOMEDCT_US_2018_03_01:93885006 DOID:3856 UMLS_CUI:C0153606 UMLS_CUI:C0017417 malignant tumor of male Reproductive system male genital cancer A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum. male genital neoplasm male reproductive system neoplasm disease NCI:C2991 DOID:4 A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. UMLS_CUI:C0012634 SNOMEDCT_US_2018_03_01:64572001 disease_ontology MESH:D004194 agnosia DOID:4019 SNOMEDCT_US_2018_03_01:6950007 DOID:4090 A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss. MESH:D001072 SNOMEDCT_US_2018_03_01:68345001 Dyspraxia Dyspraxia syndrome MESH:D000377 UMLS_CUI:C0003635 GARD:8 ICD10CM:R48.2 NCI:C84542 disease_ontology SNOMEDCT_US_2018_03_01:42341009 ICD10CM:R48.1 UMLS_CUI:C0001816 autoimmune hypersensitivity disease ICD9CM:720 An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues. disease_ontology hypersensitivity reaction type II disease Xref MGI. ls:IEDB OMIM:109100 DOID:417 autoimmune disease UMLS_CUI:C0003089 glucose metabolism disease DOID:4194 disorder of glucose metabolism disease_ontology NCI:C53655 MESH:D044882 UMLS_CUI:C1257958 myopathy SNOMEDCT_US_2018_03_01:52794005 NCI:C101216 ICD10CM:G72.9 ICD10CM:M62.9 disease_ontology ICD9CM:359.9 A muscular disease in which the muscle fibers do not function resulting in muscular weakness. UMLS_CUI:C0026848 SNOMEDCT_US_2018_03_01:75047002 ICD10CM:M60-M63 DOID:423 MESH:D009135 osteosclerosis UMLS_CUI:C0029464 MESH:D010026 disease_ontology NCI:C41236 A bone remodeling disease that results_in abnormal elevated bone density or mass. DOID:4254 SNOMEDCT_US_2018_03_01:49347007 ICD10CM:Q78.2 autoimmune disease of the nervous system An autoimmune hypersensitivity disease affecting the nervous system. autoimmune nervous system disorder MESH:D020274 UMLS_CUI:C0751871 disease_ontology CSP2005:1560-5548 DOID:438 NCI:C99383 macular degeneration UMLS_CUI:C0024437 NCI:C123330 ORDO:279 A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss. DOID:4448 MTHICD9_2006:362.50 disease_ontology Macular degeneration of retina Xref MGI. myotonic disease MESH:D020967 NCI:C84913 ICD9CM:359.2 disease_ontology DOID:450 UMLS_CUI:C0553604 A muscular dystrophy that is characterized by progressive muscle wasting and weakness. ICD10CM:G71.1 epidermolysis bullosa simplex SNOMEDCT_US_2018_03_01:67144006 OMIM:601001 UMLS_CUI:C0079298 GARD:10752 ICD10CM:Q81.0 An epidermolysis bullosa that is characterized by recurrent blistering at the level of the epidermis secondary to minor trauma, which can cause limited wounds, dehydration, electrolyte abnormalities, severe infection, among other issues, and has_material_basis_in mutation in the KRT5, KRT14, or PLEC genes, which encode keratin and plectin proteins that provide resilience in skin. OMIM:615425 Epidermolysis bullosa simplex MESH:D016110 NCI:C84692 DOID:4644 disease_ontology retinal cancer disease_ontology NCI:C4800 NCI:C3216 malignant neoplasm of retina Retinal tumor DOID:4645 MESH:D019572 DOID:770 malignant tumor of retina UMLS_CUI:C0024622 ICD9CM:190.5 UMLS_CUI:C0524801 malignant Retinal neoplasm SNOMEDCT_US_2018_03_01:93987004 neoplasm of retina NCI2004_11_17:C4800 NCI2004_11_17:C3216 ICD10CM:C69.2 prostate disease disease_ontology ICD10CM:N42.9 ICD9CM:602.9 MESH:D011469 NCI:C26865 SNOMEDCT_US_2018_03_01:30281009 DOID:47 UMLS_CUI:C0033575 male reproductive system disease ICD9CM:608.9 ICD9CM:600-608.99 ICD10CM:N50.9 disease_ontology MESH:D005832 UMLS_CUI:C0017412 A reproductive system disease that affects male reproductive organs. DOID:48 SNOMEDCT_US_2018_03_01:64557000 schizophrenia ICD10CM:F20 NCI:C3362 UMLS_CUI:C0036341 EFO:0000692 ICD9CM:295.90 Xref MGI. OMIM mapping confirmed by DO. [SN]. A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. SNOMEDCT_US_2018_03_01:58214004 DOID:14734 OMIM:181500 schizophrenia-1 MESH:D012559 disease_ontology DOID:5419 ICD9CM:295 ICD10CM:F20.9 ICD9CM:295.9 kidney disease UMLS_CUI:C0022658 DOID:557 A urinary system disease that is located_in the kidney. NCI:C34843 EFO:0003086 NCI:C3149 ICD10CM:N28.9 disease_ontology nephropathy SNOMEDCT_US_2018_03_01:90708001 ICD10CM:N08 MESH:D007674 eye disease NCI:C26767 ICD10CM:H44 disease_ontology DOID:5614 UMLS_CUI:C0015397 ICD9CM:360 An eye and adnexa disease that is located_in the eye. ICD10CM:H44.9 SNOMEDCT_US_2018_03_01:79517001 DOID:2933 ICD9CM:360.9 MESH:D005128 ICD9CM:379.90 retinal disease ICD10CM:H35.9 NCI:C62601 SNOMEDCT_US_2018_03_01:29555009 MESH:D012164 disease_ontology UMLS_CUI:C0035309 SNOMEDCT_US_2018_03_01:35426003 DOID:5679 An eye disease that is located_in the retina. NCI:C26875 ICD9CM:362.9 peripheral nervous system disease CSP2005:2042-6617 SNOMEDCT_US_2018_03_01:42658009 NCI:C27580 DOID:13069 disease_ontology DOID:574 ICD10CM:G64 A nervous system disease that affects the peripheral nervous system. UMLS_CUI:C1335029 peripheral neuropathy MTH:516 NCI:C27587 NCI:C119734 peripheral nerve disease UMLS_CUI:C0031117 MESH:D010523 ICD9CM:350-359.99 genetic disease MESH:D030342 disease_ontology SNOMEDCT_US_2018_03_01:32895009 A disease that has_material_basis_in genetic variations in the human genome. DOID:630 UMLS_CUI:C0019247 NCI:C3101 migraine UMLS_CUI:C0042331 DOID:12437 migraine variant migraine with or without aura UMLS_CUI:C0149931 migraine disorder ICD10CM:G43 ICD9CM:346.9 Xref MGI. OMIM mapping confirmed by DO. [SN]. NCI:C89715 ICD10CM:G43.909 A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. OMIM:157300 MESH:D008881 EFO:0003821 disease_ontology DOID:6364 ICD10CM:G43.9 SNOMEDCT_US_2018_03_01:37796009 ICD9CM:346 connective tissue disease disease_ontology NCI:C26729 CSP2005:0729-7208 A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage. DOID:65 MESH:D003240 connective tissue disorder disorder of connective tissue UMLS_CUI:C0009782 inherited metabolic disorder A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality. Inborn Errors of Metabolism CSP2005:1849-0057 NCI2004_11_17:C34816 MESH:D008661 NCI:C34816 UMLS_CUI:C0025521 DOID:655 Metabolic hereditary disorder inborn metabolism disorder SNOMEDCT_US_2018_03_01:86095007 disease_ontology muscle tissue disease DOID:66 disease_ontology tauopathy A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain. disease_ontology MESH:D024801 UMLS_CUI:C0949664 DOID:680 disease of anatomical entity DOID:7 DOID:5 DOID:2 DOID:1 DOID:8 A disease that manifests in a defined anatomical structure. disease_ontology DOID:72 DOID:71 hematopoietic system disease NCI:C26323 MESH:D006402 disease of hematopoietic system SNOMEDCT_US_2018_03_01:34093004 blood disorder DISEASE OF THE BLOOD AND BLOOD-FORMING ORGANS MTHICD9_2006:289.9 DOID:74 ICD9CM:280-289.99 Hematological disease A disease of anatomical entity that has_material_basis_in hematopoietic cells. CSP2005:0427-3600 ICD9CM:289.9 UMLS_CUI:C0018939 Blood dyscrasia ICD9CM_2006:280-289.99 disease_ontology Blood disease ICD10CM:D75.9 MTH:NOCODE retinoblastoma neuroblastoma of Retina OMIM mapping confirmed by DO. [LS]. GARD:7563 RB - Retinoblastoma A retinal cell cancer and malignant neoplasm of retina and neuroblastoma and neuroendocrine tumors that derives_from the tissues of the retina. NCI:C7541 OMIM:180200 NCI2004_11_17:C7541 disease_ontology NCI:C6956 NCI2004_11_17:C6956 RB MESH:D012175 SNOMEDCT_US_2018_03_01:19906005 UMLS_CUI:C0035335 DOID:768 retinal cell cancer UMLS_CUI:C1335765 A malignant neoplasm that derives_from the retina. disease_ontology DOID:771 NCI:C7061 retinal degeneration UMLS_CUI:C0035304 RETINA degeneration disease_ontology degeneration of retina SNOMEDCT_US_2018_03_01:95695004 DOID:8466 A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina. NCI:C34979 MTH:649 MESH:D012162 nervous system disease A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system. ICD10CM:G98.8 UMLS_CUI:C0027765 NCI:C26835 MESH:D009422 ICD10CM:G00-G99 DOID:863 ICD9CM:349.9 ICD10CM:G98 disease_ontology neuropathy SNOMEDCT_US_2018_03_01:42658009 DOID:870 peripheral neuropathy UMLS_CUI:C0442874 ICD10CM:G62.9 NCI:C4731 disease_ontology A nervous system disease that is located_in nerves or nerve cells. autosomal dominant polycystic kidney disease POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 DOID:898 MESH:D007690 ICD10CM:Q61.3 ORDO:730 SNOMEDCT_US_2018_03_01:82525005 disease_ontology NCI:C75464 Congenital biliary ectasias GARD:7419 A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion. UMLS_CUI:C0022680 ICD9CM:753.12 Xref MGI. OMIM mapping confirmed by DO. [SN]. Updating outdated UMLS CUI. Removing Caroli disease as a synonym as this is a distinct disease. erythromelalgia SNOMEDCT_US_2018_03_01:37151006 DOID:9240 UMLS_CUI:C0014804 OMIM:133020 ICD10CM:I73.81 ICD9CM:443.82 GARD:6377 MESH:D004916 disease_ontology NCI:C34593 frontotemporal dementia Wilhemsen-Lynch disease disease_ontology frontotemporal lobar degeneration multiple system tauopathy with presenile dementia MESH:D057180 SNOMEDCT_US_2018_03_01:42369001 GARD:8436 OMIM:600795 DOID:9255 OMIM:600274 Xref MGI. OMIM mapping confirmed by DO. [SN]. MESH:C563003 A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language. ORDO:282 pallidopontonigral degeneration UMLS_CUI:C0520716 diabetes mellitus MESH:D003920 disease_ontology DOID:9351 ICD9CM:250 NCI:C2985 SNOMEDCT_US_2018_03_01:73211009 UMLS_CUI:C0011849 A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. ICD10CM:E08-E13 brain disease ICD9CM:348.30 disease_ontology UMLS_CUI:C0006111 DOID:8510 ICD10CM:G93.9 encephalopathy NCI:C26920 A central nervous system disease that is located_in the brain. NCI:C96413 SNOMEDCT_US_2018_03_01:76011009 ICD10CM:G93.40 ICD9CM:348.3 DOID:936 SNOMEDCT_US_2018_03_01:81308009 MESH:D001927 UMLS_CUI:C0085584 ICD9CM:348.9 lipid storage disease ICD9CM:272.7 UMLS_CUI:C0023794 ICD9CM:272.8 DOID:10583 MTHICD9_2006:272.7 disease_ontology A lysosomal storage disease that involves the accumulation of harmful amounts of lipids (fats) in some of the body's cells and tissues. SNOMEDCT_US_2018_03_01:10741005 lipoidosis DOID:9455 SNOMEDCT_US_2018_03_01:11455007 inborn lipid storage disorder UMLS_CUI:C0029591 MESH:D008064 Lipoidosis ICD10CM:E75.6 Lipoid storage diseas CSP2005:1849-5707 muscular dystrophy ICD9CM:359.1 OMIM:309930 NCI:C84910 OMIM:309950 DOID:9884 OMIM:600416 ICD10CM:G71.0 A myopathy is characterized by progressive skeletal muscle weakness degeneration. GARD:7922 OMIM:159050 UMLS_CUI:C0026850 MESH:D009136 SNOMEDCT_US_2018_03_01:44292004 OMIM:310000 SNOMEDCT_US_2018_03_01:73297009 OMIM:158800 OMIM:310095 disease_ontology osteoblast differentiation osteoblast differentiation 成骨细胞分化 cellular_component cellular_component 细胞组分 A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). GO:0005575 GO:0008372 NIF_Subcellular:sao-1337158144 NIF_Subcellular:sao1337158144 Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code "no data" (ND), is used to indicate this. cell or subcellular entity cellular component cellular_component subcellular entity cell cell 细胞 GO:0005623 NIF_Subcellular:sao1813327414 The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Wikipedia:Cell_(biology) cell and encapsulating structures cellular_component movement of cell or subcellular component movement of cell or subcellular component 细胞或亚细胞组分的运动 biological_process biological_process 生物_过程 Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. GO:0000004 GO:0007582 GO:0008150 Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. Wikipedia:Biological_process biological process biological_process physiological process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. GO:0000004 GO:0007582 GO:0008150 Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. Wikipedia:Biological_process biological process biological_process physiological process 任何与整体生命功能相关的过程：细胞、组织、器官和生物体。一个过程是一个具有定义的开始和结束的分子事件的集合。 生物_过程 生物过程 生理过程 维基百科：生物_过程 需要说明的是，除了形成生物过程本体的根节点之外，还推荐将该术语用于生物过程未知的基因产物的注释。请注意，当这个术语被用于注释时，它表示没有关于从注释日期开始注释的基因产物的生物过程的信息;证据代码ND，没有数据，用来表示这一点。 cellular process cellular process 细胞过程 Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0008151 GO:0009987 GO:0050875 biological_process cell growth and/or maintenance cell physiology cellular physiological process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0008151 GO:0009987 GO:0050875 biological_process cell growth and/or maintenance cell physiology cellular physiological process 在细胞水平上进行的任何过程，但不一定限于单个细胞。例如，细胞通讯发生在多于一个的细胞中，但发生在细胞水平。 生物_过程 细胞生理学 细胞生理过程 细胞生长和/或维持 cell migration cell migration 细胞迁移 stem cell division stem cell division 干细胞分裂 cell differentiation cell differentiation 细胞分化 neuron differentiation neuron differentiation 神经元分化 epithelial cell differentiation epithelial cell differentiation 上皮细胞分化 developmental process developmental process 发展进程 macromolecular complex macromolecular complex 大分子复合物 cardiocyte differentiation cardiocyte differentiation 心肌细胞分化 locomotion locomotion 运动 GO:0040011 Self-propelled movement of a cell or organism from one location to another. biological_process GO:0040011 Self-propelled movement of a cell or organism from one location to another. biological_process 一个细胞或有机体从一个位置到另一个位置的自主运动。 生物_过程 MHC protein complex MHC protein complex MHC蛋白复合物 MHC class II protein complex MHC class II protein complex MHCⅡ类蛋白复合物 muscle cell differentiation muscle cell differentiation 肌细胞分化 protein complex protein complex 蛋白复合物 membrane part membrane part 膜部分 plasma membrane part plasma membrane part 质膜部分 cell part cell part 细胞部分 single-organism process 单一生物过程 single-organism cellular process single-organism cellular process 单个有机体的细胞过程 2012-12-11T16:56:55Z Any process that is carried out at the cellular level, occurring within a single organism. GO:0044763 biological_process janelomax 2012-12-11T16:56:55Z Any process that is carried out at the cellular level, occurring within a single organism. GO:0044763 biological_process janelomax 在细胞水平上进行的任何过程，发生在单个生物体内。 生物_过程 single-organism developmental process 单一生物体发育过程 fat cell differentiation fat cell differentiation 脂肪细胞分化 cellular developmental process cellular developmental process 细胞发育过程 cell motility cell motility 细胞运动 striated muscle cell differentiation striated muscle cell differentiation 横纹肌细胞分化 cell division cell division 细胞分裂 cardiac muscle cell differentiation cardiac muscle cell differentiation 心肌细胞分化 chondroblast differentiation chondroblast differentiation 成软骨细胞分化 membrane protein complex membrane protein complex 膜蛋白复合物 plasma membrane protein complex plasma membrane protein complex 质膜蛋白复合物 objective specification 目标说明 2009-03-16: original definition when imported from OBI read: "objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed." 2014-03-31: In the example of usage ("In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that. Answers the question, why did you do this experiment? In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction. OBI Plan and Planned Process/Roles Branch OBI_0000217 PERSON: Alan Ruttenberg PERSON: Barry Smith PERSON: Bjoern Peters PERSON: Jennifer Fostel a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved. goal specification objective specification 2009-03-16：从OBI引入的原始定义如下：“目标是一个不可实现的信息实体，它可以作为计划的适当部分朝着该计划的实现。” 2014-03-31：在使用的例子中（“在ChIP分析的方案中，客观规范说明了蛋白质和DNA相互作用的鉴定”），有一种方案是ChIP分析方案。该协议除了在纸上的具体化，还可以具体化为一个可实现的实体，例如一个人的计划。客观的规范是说一些蛋白质和DNA相互作用被识别的部分。这是一个过程终点的规范：过程中的边界，在这个过程之前，它们没有被识别，并且在这之后，它们被识别了。在实现这个计划的过程中，我们的目标是达到相互作用的目的，并且实现这个计划的参与者试图做到这一点。 OBI计划和计划过程/角色分支 一个指示信息实体，其描述预期过程终点。当一个计划规范的一部分，具体的过程是在一个计划的过程中实现的，在这个过程中，承载者试图影响世界，从而实现过程终点。 回答这个问题，你为什么做这个实验？ 在ChIP分析的方案中，这个客观规格说明了蛋白质和DNA相互作用的鉴定。 目标规范 目标说明 action specification 动作说明 Alan Ruttenberg OBI Plan and Planned Process branch Pour the contents of flask 1 into flask 2 a directive information entity that describes an action the bearer will take action specification OBI计划和计划过程分支 一个指导信息实体，其描述承载者将采取的行动 动作说明 将烧瓶1的内容物倒入烧瓶2中 data item 数据条目 2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/ 2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers. 2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum. 2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym. 2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/ Data items include counts of things, analyte concentrations, and statistical summaries. JAR: datum -- well, this will be very tricky to define, but maybe some information-like stuff that might be put into a computer and that is meant, by someone, to denote and/or to be interpreted by some process... I would include lists, tables, sentences... I think I might defer to Barry, or to Brian Cantwell Smith JAR: A data item is an approximately justified approximately true approximate belief JAR: datum -- 好吧，这将是非常棘手的定义，但也许一些 类似信息的东西可能会被放入计算机中 意思是由某人指示和/或被某些人过程解释 ... 我会纳入名单，表格，句子... 我想我可能会 遵从 Barry, 或者Brian Cantwell Smith JAR: 一个数据项是近似正确的近似值 PERSON: Alan Ruttenberg PERSON: Chris Stoeckert PERSON: Jonathan Rees a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. data data item 2/2/2009 Alan和Bjoern讨论FACS运行输出数据。 这是一个数据项，因为它是关于细胞群。 每个元素记录一个事件，并且通常进一步组成一组测量数据项，这些数据项记录由其中一个激光器激发的荧光强度。 2009-03-16：删除基准（datum）作为替代术语，因为基准（datum）特指单数形式，因此不是一个确切的同义词。 2009-03-16：数据项目模糊不清：我们把数据集合和数据合并为一个实体，不知道如何定义单数与复数。 所以数据项比数据更普遍。 2014-03-31：请参阅讨论http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/ 一个数据项是一个信息内容实体，其意图是关于某事的真实陈述（模数，例如测量精度或其他系统误差），并且是通过可靠地倾向于产生（近似）真实陈述的方法构建/获取的。 数据 数据条目 数据项包括事物数量，分析物浓度和统计总结。 information content entity 信息内容实体 2014-03-10: The use of "thing" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ). A generically dependent continuant that is about some thing. Examples of information content entites include journal articles, data, graphical layouts, and graphs. OBI_0000142 PERSON: Chris Stoeckert an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity information content entity information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907). Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity. 在分割之前，信息_内容t_实体 '被_编码_在' obi的一些数字_实体中 (040907). 在分割之前信息_内容_实体 '被_编码_在' obi的一些物理_文件中 (040907). 先前. 信息内容实体是不可实现的信息实体，其被“编码成” 一些数字或物理实体。 2014-03-10：使用“事物”旨在足够普遍，包括共相和配置（请参阅https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ）。 一个普遍依赖性常体，其涉及一些事物。 信息内容实体 信息内容实体是一般依赖于某个人造物的实体，并与某个实体的关系有关 信息内容的例子包括期刊文章、数据、图形布局和图表。 directive information entity 指令信息实体 2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was "is the specification of a process that can be concretized and realized by an actor" with alternative term "instruction".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term. 2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it. 8/6/2009 Alan Ruttenberg: Changed label from "information entity about a realizable" after discussions at ICBO An information content entity whose concretizations indicate to their bearer how to realize them in a process. PERSON: Alan Ruttenberg PERSON: Bjoern Peters Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan directive information entity 2009-03-16：出处：一个术语可实现的信息实体被提出应用于OBI（OBI_0000337），由PlanAndPlannedProcess分支编辑。原始定义是“可由具体行动者具体化和实现的过程的说明”并用替代术语“指令”来表示。随后，它被移到了IAO，其中定义了原始术语的目标满足于这个不同的术语的定义。 2009年8月6日Alan Ruttenberg：经过ICBO讨论从“关于可实现的信息实体”改变标签 2013-05-30 Alan Ruttenberg：指令信息实体与信息具体化的区别在于它可以具体化，可以是属性或可实现的实体。当个人选择了这个方向时，即具有（试图）实现它的意图，具体化是所创造的可实现实体。 Werner把它称为可实现的信息实体，因为它是不可实现的。然而这个名字也不正确。一个例子是一个配方。可实现的实体将是一个计划，但信息实体并不关于该计划，它一旦具体化就是计划。 -Alan 一个信息内容实体，其具体化向其承载者指示如何在一个过程中实现它们。 指令信息实体 curation status specification 管理状态说明 Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting) GROUP:OBI:<http://purl.obolibrary.org/obo/obi> OBI_0000266 PERSON:Bill Bug The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. curation status specification 更好地把管理作为一个过程的一部分，然后把标签与这个过程联系起来（在IAO会议上） 管理状态说明 该术语的管理状态。允许值来自预定义术语的枚举列表。有关每个枚举值的更详细定义，请参阅这些实例的规范。 data about an ontology part 关于本体部分的数据 Person:Alan Ruttenberg Person:Alan Ruttenberg data about an ontology part data about an ontology part is a data item about a part of an ontology, for example a term 关于本体部分的数据 关于本体部分的数据是关于本体的一部分的数据项，例如一个术语 plan specification 计划说明 2/3/2009 Comment from OBI review. Action specification not well enough specified. Conditional specification not well enough specified. Question whether all plan specifications have objective specifications. Request that IAO either clarify these or change definitions not to use them 2/3/2009 来自OBI综述的评论. 动作规范说明不够好。 条件规范说明不够好。 质疑所有计划规范是否具有客观规范。 IAO澄清这些或改变定义不使用它们的要求 2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was " a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term. 2014-03-31: A plan specification can have other parts, such as conditional specifications. A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified. Alan Ruttenberg Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved OBI Plan and Planned Process branch OBI_0000344 PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice. plan specification 2009-03-16：出处：一个术语被提出用于OBI（OBI_0000344），由PlanAndPlannedProcess分支编辑。原始定义是“计划是由参与者实现以实现作为计划的一部分的指定目标的过程的说明“。随后移到了IAO，原定义的目标满足于这个不同的术语的定义。 2014-03-31：计划规范可以包含其他部分，如条件规范。 OBI计划和计划过程分支 一个指令信息实体，当具体化时，具有行为规范和客观规范部分，在承载者试图通过指定的动作达到目标的过程中实现。 替代以前定义：一个计划是一组指示如何实现一个目标 计划说明 Viruses Viruses 病毒 Viruses Viruses 病毒 Euteleostomi Euteleostomi 骨脊椎动物 Euteleostomi bony vertebrates Euteleostomi GC_ID:1 NCBITaxon:40673 bony vertebrates bony vertebrates ncbi_taxonomy 多骨脊椎动物(bony vertebrates) 骨脊椎动物 Boreoeutheria 北方真兽类 Boreotheria GC_ID:1 PMID:11743200 PMID:11791233 ncbi_taxonomy Bacteria Bacteria 细菌 Bacteria eubacteria Bacteria eubacteria 真细菌(eubacteria) 细菌 Homininae Homininae 人亚科 Homininae Homininae 人亚科 Archaea Archaea 古生菌 Archaea Archaea 古生菌 Eukaryota Eukaryota 真核生物(Eukaryota) Eukaryota eucaryotes eukaryotes Eucarya Eucarya Eucaryotae Eucaryotae Eukarya Eukarya Eukaryota Eukaryotae Eukaryotae GC_ID:1 GC_ID:1 NCBITaxon:2759 PMID:23020233 PMID:23020233 eucaryotes eucaryotes eucaryotes euk- eukaryotes eukaryotes eukaryotes eukaryotes eukaryotes ncbi_taxonomy ncbi_taxonomy 真核生物(Eucarya) 真核生物(Eukarya) 真核生物(Eukaryota) 真核生物(eucaryotes) 真核生物(eucaryotes) 真核生物(eukaryotes) 真核生物(eukaryotes) 真核生物(eukaryotes) 真核生物界(Eucaryotae) 真核生物界(Eukaryotae) Euarchontoglires Euarchontoglires 灵长总目 Euarchontoglires Euarchontoglires GC_ID:1 PMID:11214319 PMID:12082125 PMID:12878460 PMID:15522813 ncbi_taxonomy 灵长总目 Simiiformes Simiiformes 类人猿下目 Simiiformes Simiiformes 类人猿下目 Hominoidea Hominoidea 人猿总科 "ape" EXACT common_name [] "apes" EXACT common_name [] GC_ID:1 Hominoidea URI: http://www.ebi.ac.uk/cellline#Hominoidea ape apes "ape" EXACT common_name [] "apes" EXACT common_name [] GC_ID:1 Hominoidea URI: http://www.ebi.ac.uk/cellline#Hominoidea ape apes “猿(ape)” EXACT common_name [] “猿(apes)” EXACT common_name [] 人猿总科 猿(ape) 类人猿(apes) Tetrapoda Tetrapoda 四足动物总纲 Tetrapoda tetrapods Tetrapoda tetrapods 四足动物(tetrapods) 四足动物总纲 Amniota Amniota 羊膜类 Amniota amniotes Amniota GC_ID:1 amniotes amniotes ncbi_taxonomy 羊膜(amniotes) 羊膜类 Theria <Mammalia> Theria <Mammalia> 真兽亚纲<哺乳类> Theria Theria <Mammalia> Theria Theria <Mammalia> 兽亚纲(Theria) 真兽亚纲<哺乳类> Opisthokonta Opisthokonta 后鞭毛生物 Opisthokonta Fungi/Metazoa group Fungi/Metazoa group GC_ID:1 NCBITaxon:33154 Opisthokonta ncbi_taxonomy ncbi_taxonomy opisthokonts opisthokonts 后鞭毛生物 后鞭毛生物 真菌/后生动物组 Metazoa 后生动物 Animalia NCBITaxon:33208 animals metazoan- metazoans multicellular animals ncbi_taxonomy 动物(animals) 动物界 后生动物 多细胞动物 Bilateria Bilateria 两侧对称动物 Bilateria Bilateria GC_ID:1 ncbi_taxonomy 两侧对称动物 Mammalia Mammalia 哺乳动物 "mammals" EXACT genbank_common_name [] "mammals" RELATED blast_name [] GC_ID:1 Mammalia URI: http://www.ebi.ac.uk/cellline#Mammalia mammals "mammals" EXACT genbank_common_name [] "mammals" RELATED blast_name [] GC_ID:1 GC_ID:1 Mammalia NCBITaxon:40674 URI: http://www.ebi.ac.uk/cellline#Mammalia mammal mammal- mammals mammals mammals ncbi_taxonomy ncbi_taxonomy “哺乳动物(mammals)” EXACT genbank_common_name [] “哺乳动物(mammals)” RELATED blast_name [] 哺乳动物 哺乳动物(mammals) Eumetazoa 真后生动物 Vertebrata <Metazoa> Vertebrata <Metazoa> 脊椎动物门<后生动物> Vertebrata Vertebrata <Metazoa> vertebrates GC_ID:1 Vertebrata Vertebrata Vertebrata <Metazoa> ncbi_taxonomy vertebrates vertebrates vertebrates 脊椎动物(Vertebrata) 脊椎动物(vertebrates) 脊椎动物门<后生动物> Craniata <chordata> Craniata <chordata> 脊椎动物门<脊索动物> Craniata Craniata <chordata> Craniata Craniata <chordata> 脊椎动物亚门(Craniata) 脊椎动物门<脊索动物> Eutheria Eutheria 真兽亚纲 Eutheria eutherian mammals placental mammals placentals Eutheria eutherian mammals placental mammals placentals 有胎盘类(placentals) 真兽亚纲 真兽类哺乳动物(eutherian mammals) 胎盘哺乳动物(placental mammals) Primates Primates 灵长目 "Primata" RELATED synonym [] "primate" EXACT equivalent_name [] "primates" RELATED blast_name [] GC_ID:1 Primates URI: http://www.ebi.ac.uk/cellline#Primates primate "Primata" RELATED synonym [] "primate" EXACT equivalent_name [] "primates" RELATED blast_name [] GC_ID:1 Primates URI: http://www.ebi.ac.uk/cellline#Primates primate “灵长目(Primata)” RELATED synonym [] “灵长类(primate)” EXACT equivalent_name [] “灵长类(primates)” RELATED blast_name [] 灵长目 灵长类动物(primate) Catarrhini Catarrhini 狭鼻类 Catarrhini Catarrhini 狭鼻类 Hominidae Hominidae 人科 "Pongidae" RELATED synonym [] "great apes" EXACT common_name [] GC_ID:1 Hominidae URI: http://www.ebi.ac.uk/cellline#Hominidae great apes "Pongidae" RELATED synonym [] "great apes" EXACT common_name [] GC_ID:1 Hominidae URI: http://www.ebi.ac.uk/cellline#Hominidae great apes “猩猩科(Pongidae)” RELATED synonym [] “类人猿(great apes)” EXACT common_name [] 人科 类人猿(great apes) Homo sapiens Homo sapiens 人类 "human" EXACT genbank_common_name [] GC_ID:1 Homo sapiens URI: http://www.ebi.ac.uk/cellline#Homo_sapiens human human being man "human" EXACT genbank_common_name [] GC_ID:1 GC_ID:1 Homo sapiens NCBITaxon:9606 URI: http://www.ebi.ac.uk/cellline#Homo_sapiens h human human human human being man man ncbi_taxonomy “人” EXACT genbank_common_name [] 人(human being) 人(human) 人(man) 人类 planned process 计划过程 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.) 6/11/9: Edited at workshop. Used to include: is initiated by an agent Bjoern Peters Injecting mice with a vaccine in order to test its efficacy We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some objectives is a planned process. branch derived 我们只考虑成功完成计划的流程。 计划可能会被修改，并会在执行过程中添加详细信息。 对于给定的计划流程，相关的已实现计划规范是包含执行期间所做的所有更改的计划规范。 这意味着代理人实现某些目标的所有过程 objectives is a planned process. 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.) 6/11/9: Edited at workshop. Used to include: is initiated by an agent A processual entity that realizes a plan which is the concretization of a plan specification. Bjoern Peters Injecting mice with a vaccine in order to test its efficacy This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call) branch derived planned process 6/11/9：在研讨会上编辑。用来包含：由代理发起 “计划者”：包括未来的方向感。如果计划在执行过程中发生改变，这可能会有问题。然而，即使代理人之前没有考虑到，在他的脑中可能被认为是计划的一部分的协议，也存在隐含的意外事件。因此，计划过程可以与执行之前中代理人所说的计划不同，通过执行过程中遇到的问题调整（例如，如果原计划中的试剂用完，则选择具有相同性质的另一种试剂）。 一个实现计划的过程实体，是计划规范的具体化。 分支派生 用疫苗注射小鼠以测试其功效 计划过程 这个类合并了以前分离的目标驱动过程和计划过程，因为他们之间的缺口难以维护。 （1/22/09，分公司） processed material 加工物质 Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples Is a material entity that is created or changed during material processing. PERSON: Alan Ruttenberg processed material 加工物质 实例包括凝胶基质、滤纸、石蜡膜和缓冲溶液、质谱仪、组织样品 是在物质处理过程中创建或更改的物质实体。 culture medium 培养基 a processed material that provides the needed nourishment for microorganisms or cells grown in vitro. changed from a role to a processed material based on on Aug 22, 2011 dev call. Details see the tracker item: http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178 Modification made by JZ. 根据2011年8月22日的dev call，将其从角色更改为已处理的材料。 详情请参阅跟踪项目： http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178 JZ进行修改。 A growth medium or culture medium is a substance in which microorganisms or cells can grow. Wikipedia, growth medium, Feb 29, 2008 OBI Person: Jennifer Fostel, Jie Zheng a processed material that provides the needed nourishment for microorganisms or cells grown in vitro. culture medium 为体外培养的微生物或细胞提供所需营养的加工材料。 培养基 生长培养基或培养基是微生物或细胞可以在其中生长的物质。维基百科，生长培养基，2008年2月29日 material processing 物质加工 A cell lysis, production of a cloning vector, creating a buffer. PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca Serra A cell lysis, production of a cloning vector, creating a buffer. A planned process which results in physical changes in a specified input material OBI branch derived PERSON: Bjoern Peters PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca Serra material processing material transformation OBI分支派生 导致指定的输入物质发生物理变化的计划过程 物质加工 物质转化 细胞裂解，克隆载体产生，缓冲液配制。 organization organization 组织 An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. EFO_URI: http://www.ebi.ac.uk/efo/EFO_0002010 GROUP: OBI James Malone Jie Zheng MO_177 PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Philippe Rocca-Serra PERSON: Susanna Sansone Tomasz Adamusiak organisation An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that. The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based: 1) there are organization_member_roles (president, treasurer, branch editor), with individual persons as bearers 2) there are organization_roles (employer, owner, vendor, patent holder) 3) an organization has a charter / rules / bylaws, which specify what roles there are, how they should be realized, and how to modify the charter/rules/bylaws themselves. It is debatable what the organization itself is (some kind of dependent continuant or an aggregate of people). This also determines who/what the bearer of organization_roles' are. My personal favorite is still to define organization as a kind of 'legal entity', but thinking it through leads to all kinds of questions that are clearly outside the scope of OBI. Interestingly enough, it does not seem to matter much where we place organization itself, as long as we can subclass it (University, Corporation, Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO, W3C, University of Oklahoma), and have it play roles. This leads to my proposal: We define organization through the statements 1 - 3 above, but without an 'is a' statement for now. We can leave it in its current place in the is_a hierarchy (material entity) or move it up to 'continuant'. We leave further clarifications to BFO, and close this issue for now. BP：定义总结了关于OBI开发者、角色、生物材料和否定者分支机构的长时间电子邮件讨论。如果一个组织是一个物质实体或一个依赖性常体，它就会开放，因为没有达成共识。因此，目前作为材料的安排是暂时的，以便随着发展而前进。以下是定义所依据的整个电子邮件的总结： 1）有组织会员（总裁，会计，分支机构 编辑），个人作为承担者 2）有组织_角色（雇主，所有者，供应商，专利持有人） 3）组织有一个章程/规定/细则，规定了哪些角色 有，应该如何实现，以及如何修改 章程/规定/细则本身。 值得商榷的是组织本身是什么（某种程度上的依赖性 常体或一群人）。这也决定了谁/什么 组织角色的持有者“是。我个人最喜欢的还是定义 组织作为一种“法律实体”，但是通过它会导致 各种明显超出OBI范围的问题。 有趣的是，我们放置的位置似乎并不重要 组织本身，只要我们可以将其子类化（大学、公司、 政府机构、医院），实例化它（Affymetrix、NCBI、NIH、ISO、 W3C、俄克拉荷马大学），并发挥其作用。 这引出了我的建议：我们通过陈述1 - 3来定义组织 但目前没有一个“是一个”的声明。我们可以把它留在其 在is_a层次结构（物质实体）中的当前位置或将其移动到 '常体'上。我们对BFO进一步澄清，并暂时关闭这个问题 EFO_URI: http://www.ebi.ac.uk/efo/EFO_0002010 GROUP: OBI James Malone Jie Zheng MO_177 PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Philippe Rocca-Serra PERSON: Susanna Sansone PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods. Tomasz Adamusiak organisation organization 一个可以担任角色的实体，有成员，并有一套组织规则。组织成员既可以是组织自己也可以是个人。成员可以承担在组织规则中确定的特定组织成员角色。组织规则还决定组织成员如何代表组织做出决定。 一个组织是一个可以扮演角色，有成员，有一套组织规则的连续性实体。组织成员既可以是组织自己也可以是个人。成员可以承担在组织规则中确定的特定组织成员角色。组织规则还决定组织成员如何代表组织做出决定。 组织 组织 material transformation objective 物质转化目标 GROUP: OBI PlanAndPlannedProcess Branch PERSON: Bjoern Peters PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS. GROUP: OBI PlanAndPlannedProcess Branch PERSON: Bjoern Peters PERSON: Frank Gibson PERSON: Jennifer Fostel PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS. an objective specifiction that creates an specific output object from input materials. artifact creation objective material transformation objective 人工创造的目标 创建一只感染LCM病毒的小鼠的目标。配制一个明确定义的PBS溶液的目标。 可以从输入材料创建特定的输出对象的目标设定 物质转化目标 组：OBI PlanAndPlannedProcess分支 material separation objective material separation objective 物质分解目标 PPPB branch PPPB branch The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood. is an objective to transform a material entity into spatially separated components. material separation objective PPPB branch PPPB branch The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood. is an objective to transform a material entity into spatially separated components. material separation objective PPPB分支 PPPB分支 物质分解目标 目的是将一个物质实体转化为空间分离的成分。 目的是获得多个等分的酶制剂。获得血液样本中所含细胞的目标。 portioning objective portioning objective 分配目标 A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material. The objective to obtain multiple aliquots of an enzyme preparation. portioning objective A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material. The objective to obtain multiple aliquots of an enzyme preparation. portioning objective 一个材料分离目标，旨在将材料分成多个部分，每个部分都包含一个相似的输入材料组成。 分配目标 目的是获得多个等分的酶制剂。 separation into different composition objective separation into different composition objective 分离成不同的组成目标 A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities). The objective to obtain cells contained in a sample of blood. We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives separation into different composition objective A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities). The objective to obtain cells contained in a sample of blood. We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives separation into different composition objective 一个材料分离目标，旨在分离具有不同类型部分的材料实体，并且以至少一个输出为少类型部分（模数杂质）的材料结束。 分离成不同的组成目标 我们应该用粮食的关系或密度来区别划分和其他子目标 获得血液样本中所含细胞的目标。 material maintenance objective material maintenance objective 物质维持目标 An objective specification maintains some or all of the qualities of a material over time. PERSON: Bjoern Peters material maintenance objective PERSON: Bjoern Peters An objective specification maintains some or all of the qualities of a material over time. PERSON: Bjoern Peters PERSON: Bjoern Peters material maintenance objective 在一段时间内保持了一种材料的一些或全部特性的。 物质维持目标 material maintenance material maintenance 物质维持 a process with that achieves the objective to maintain some or all of the characteristics of an input material over time material maintenance a process with that achieves the objective to maintain some or all of the characteristics of an input material over time material maintenance 物质维持 这个过程一段时间内实现了保持输入材料的部分或全部特性的目标 secondary cultured cell secondary cultured cell 二次培养细胞 A cultured cell that has been passaged or derives from a cell that has been passaged in culture. A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture. PERSON: Matthew Brush The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. secondary cultured cell A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture. Person: Matthew Brush A cultured cell that has been passaged or derives from a cell that has been passaged in culture. PERSON: Matthew Brush Person: Matthew Brush The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. secondary cultured cell 二次培养细胞 已经传代或来源于已经在培养中传代的细胞的培养细胞。 术语“次生细胞培养物” 通常用于生物学文本/协议中以指代初始传代后的任何细胞培养物。 我们把它包括在内，因为在初级培养和建立一个稳定的同质细胞系之间要经历很多代。 这样的培养物被认为是“次生培养物”； 但不是“细胞系”； 在它们的衍生物从“原代细胞培养物”到“细胞系”的中间传代/选择期间，这是更具体类型的次生培养物。 次生培养细胞已经在培养物中传代，或者是通过培养增殖获得的这种细胞的后代。 establishing cell line establishing cell line 建立细胞系 2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and progatated over time. PERSON:Matthew Brush Person: Matthew Brush establishing cell line 2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and progatated over time. Person: Matthew Brush establishing cell line 这个过程是通过将原代细胞培养物传代至相对遗传稳定性和组成均一性细胞培养物，或通过对现有细胞系的一些实验性修饰以产生具有新特征的新细胞系（例如永生化或一些其他稳定的遗传修饰，或选择某些定义的子集）。 2013-4-20 MHB：对于从原代培养物初始建立株系的情况，与输入原代培养物相比，连续传代和/或选择过程可赋予更多的遗传稳定性和组成均一性。 从历史上看，许多理论认为第一代是界定一个细胞系起始的最明确的时间点。 然而，实际上更常见的情况是，在认为培养物具有足够的稳定性和同质性以被认为是细胞系之前，可能需要多于一次的传代以及可能的附加的选择性技术。 这是OBI所采取的观点。 无论如何，重要的是，已经采取了一些有意的尝试性的步骤来建立一个更加同质和稳定的培养，这种培养可以随着时间的推移而被表征和发展。 PERSON:Matthew Brush a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics (e.g. immortalization or some other stable genetic modification, or selection of some defined subset). a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics (e.g. immortalization or some other stable genetic modification, or selection of some defined subset). 建立细胞系 secondary cultured cell population secondary cultured cell population 二次培养细胞群 secondary cell culture sample A cultured cell population that is derived through one or more passages in culture. secondary cultured cell population A cultured cell population that is derived through one or more passages in culture. The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. 通过一次或多次培养得到的一个培养细胞群。 The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. PERSON:Matthew Brush PERSON:Matthew Brush PERSON:Matthew Brush PERSON:Matthew Brush The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. secondary cell culture sample secondary cultured cell population 二次培养细胞群 二次细胞培养样品 术语“次生细胞培养物” 通常用于生物学文本/协议中以指代初始传代后的任何细胞培养物。 我们把它包括在内，因为在初级培养和建立一个稳定的同质细胞系之间要经历很多代。 这样的培养物被认为是“次生培养物”； 但不是“细胞系”； 在它们的衍生物从“原代细胞培养物”到“细胞系”的中间传代/选择期间，这是更具体类型的次生培养物。 cell freezing medium 细胞冻存液 A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. PERSON: Matthew Brush A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. PERSON: Matthew Brush culture media or serum + 10% DMSO is often used as cell freezing media. cell freezing medium culture media or serum + 10% DMSO is often used as cell freezing media. 一种处理过的材料，作为一种液体媒介，用于冷冻细胞以长期静止保存，其中含有在冻融循环中维持细胞活力所需的化学物质。 培养基或血清+ 10％DMSO通常用作细胞冷冻培养基。 细胞冻存液 organism organism 生物体 10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms') 13-02-2009: OBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus. This issue is outside the scope of OBI. 13-02-2009: OBI 并不确定生物体何时开始或结束成为生物体 - 例如 精子，胎儿。 这个问题超出了OBI的范围。 A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. E.g Drosophila melanogaster Drosophila melanogaster EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000634 GROUP: OBI Biomaterial Branch James Malone Jie Zheng MO_508 NIFSTD:birnlex_376 Tomasz Adamusiak 10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms') A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. E.g Drosophila melanogaster Drosophila melanogaster EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000634 GROUP: OBI Biomaterial Branch James Malone Jie Zheng MO_508 NIFSTD:birnlex_376 OBI:0100026 Tomasz Adamusiak WEB: http://en.wikipedia.org/wiki/Organism animal fungus obi organism plant virus 10/21/09：这是一个占位符术语，理想情况下应从NCBI分类法中导入，但是高级别的层次结构不符合我们的需要（包括质粒和“其他生物体”） 一个物质实体，是能够在正确的环境中复制，繁殖，生长和维护的个体生命系统，如动物，植物，细菌或病毒。生物体可能是单细胞的，或像人类一样，由数十亿个分化成特定的组织和器官的细胞组成。 一个物质实体，是能够在正确的环境中复制，繁殖，生长和维护的个体生命系统，如动物，植物，细菌或病毒。生物体可能是单细胞的，或像人类一样，由数十亿个分化成特定的组织和器官的细胞组成。 一个物质实体，是能够在正确的环境中复制，繁殖，生长和维护的个体生命系统，如动物，植物，细菌或病毒。生物体可能是单细胞的，或像人类一样，由数十亿个分化成特定的组织和器官的细胞组成。例如黑腹果蝇（Drosophila melanogaster） 动物 植物 生物体 病毒 菌 黑腹果蝇 cultured cell population cultured cell population 培养细胞群 A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. PERSON:Matthew Brush PERSON:Matthew Brush The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. cultured cell population 2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line. A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. PERSON:Matthew Brush PERSON:Matthew Brush The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. cell culture sample cell culture sample cultured cell population 2013-6-5 MHB：这个OBI类以前被称为“细胞培养”，但标签在2013年春季CLO比对工作之后发生了变化和定义更新，在此期间本类的意图被澄清，指的是培养的某些部分或而不是一个完整的细胞培养或细胞系。 “培养细胞群”的范围仅限于所有细胞成员必须共享一个增殖历史（即通过一个原始培养物的一个共同的谱系衍生）。在这样定义下，这个类可以用来指研究人员在科学实践中实际使用的群体—即培养、实验和共享的投入。这些群体中的细胞将是相对均匀的群体，因为它们经历连续的共同增殖而经历了类似的选择压力。这个群体也会有一个单一的数字，同样是由于他们共同的增殖史。培养细胞群仅代表细胞的集合（即，不包括培养基，培养皿等），并且包括培养的单细胞生物或培养的多细胞生物细胞的群体。它们可以在活跃的细胞培养中存在，以静止的状态存储以供将来使用，或者应用于实验。 在实验中应用的培养细胞群体：“表达TrkA的293细胞血清饥饿18小时，然后在细胞收获之前加入神经营养因子10分钟。” (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). 体外维持的培养细胞群体：“来自15天胚胎的大鼠皮层神经元在解离的细胞培养物中生长并在体外维持8-12周” (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). 培养细胞群 由一种培养细胞集合构成的加工材料，这些细胞在培养中一直保持在一起，并具有共同的增殖历史。 细胞培养样品 material component separation 物质成分分离 Bjoern Peters IEDB Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification a material processing in which components of an input material become segregated in space material component separation 使用细胞分选仪将T细胞混合物分成两部分；一个表面受体CD8，另一个缺乏受体或纯化 物质成分分离 输入物质的成分在空间中分离的物质处理 maintaining cell culture 维持细胞培养 OBI branch derived PlanAndPlannedProcess Branch When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing maintaining cell culture OBI分支派生 PlanAndPlannedProcess分支 一个协议应用程序，其中细胞在生物体外定义的环境中保持存活。细胞_培养的一部分 当从人体采集血液时，分离T细胞，然后限制细胞的稀释克隆，维持_细胞_培养步骤包括初始稀释并将细胞铺在培养物中的所有步骤，例如将培养物置于培养箱中，更换或添加培养基，分离细胞培养物 维持细胞培养 establishing cell culture establishing cell culture 建立细胞培养 这个过程是通过从一个新鲜来源分离和培养一种或多种细胞或者对现有的细胞培养物进行有意的实验性修饰以形成一种新的细胞培养物或细胞系（例如将原代培养物传代以产生二次培养物或细胞系，或对现有培养物或细胞系的永生化或稳定遗传修饰）。 PERSON:Matthew Brush A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics. This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms. A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics. This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms. establishing cell culture a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line). PERSON:Matthew Brush PERSON:Matthew Brush PERSON:Matthew Brush a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line). establishing cell culture 建立细胞培养 cell culture splitting 细胞培养分离 cell culture passaging An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone. An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone. OBI branch derived PlanAndPlannedProcess Branch The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media. The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing cell culture passaging cell culture splitting OBI分支派生 PlanAndPlannedProcess分支 参与同质细胞培养的一部分，并创造一个或多个额外的不同培养物，具有相似的性质。输入：细胞_培养，输出细胞_培养最小基数 2.细胞培养的一部分 取高密度的细胞培养物，计数细胞，除去部分细胞，并用新组织培养基将选定数量的细胞重新接种到新的培养瓶中。 细胞培养传代 细胞培养分离 genome 基因组 A genome is a material entity that represents the entirety of an organism's hereditary information. The genome includes both the genes and the non-coding sequences of the DNA and RNA. Book: Eugene Nester, Denise Anderson, C. Evans Roberts, Jr., Microbiology (Companion Site): A Human Perspective, 7th Edition. Mcgraw Hill, October 18, 2011. ISBN-13: 978-0073375311 Oliver He WEB: http://en.wikipedia.org/wiki/Genome 基因组是一个物质实体，它代表了有机体遗传信息的全部。 基因组包括DNA和RNA的基因和非编码序列。 gene 基因 WEB: http://www.ncbi.nlm.nih.gov/books/NBK21640/ A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. Oliver He In addition to the coding regions (exons), a gene includes transcription-control regions and sometimes introns. Although the majority of genes encode proteins, some encode tRNAs, rRNAs, and other types of RNA. 基因是代表合成功能性蛋白质或RNA分子所需的全部DNA序列的物质实体。 除了编码区（外显子）外，基因还包括转录调控基因也区，有时还包括内含子。 虽然大多数基因编码蛋白质，但一些编码tRNAs，rRNAs和其他类型的RNA。 gene disposition 基因倾向 Yongqun He a disposition that a gene can be used as a blueprint for generating a new form of product such as protein. WEB: http://www.ncbi.nlm.nih.gov/IEB/ToolBox/CPP_DOC/lxr/source/src/objects/entrezgene/entrezgene.asn YH: According to NCBI Gene project, there are two gene types: unknown (0) , tRNA (1) , rRNA (2) , snRNA (3) , scRNA (4) , snoRNA (5) , protein-coding (6) , pseudo (7) , transposon (8) , miscRNA (9) , ncRNA (10) , other (255). Therefore, we have generated corresponding gene dispositions. Note that we don't use the term "gene type" here to differentiate the meanings of "type" and "disposition". 一种基因可以用作产生蛋白质等新型产物蓝图的倾向。 genome of Eukaryota 真核生物基因组 2759 The genome of an organism of Eukaryota Yue Liu, Bin Zhao, Oliver He 真核生物体的基因组 genome of Homo sapiens 人类基因组 9606 The genome of an organism of Homo sapiens Yue Liu, Bin Zhao, Oliver He 人类的基因组 gene of Eukaryota gene of Eukaryota 真核生物基因 2759 A gene of an organism of Eukaryota Yue Liu, Bin Zhao, Oliver He 2759 A gene of an organism of Eukaryota Yue Liu, Bin Zhao, Oliver He 真核生物体的一个基因 gene of Homo sapiens gene of Homo sapiens 人类基因 9606 A gene of an organism of Homo sapiens Yue Liu, Bin Zhao, Oliver He 9606 Yue Liu, Bin Zhao, Oliver He 人类生物体的一个基因 protein-coding gene of Homo sapiens 9606 A gene of Homo sapiens that has a protein-coding gene disposition Bin Zhao, Oliver He CTNNB1 1499 20140408 3 3p21 9606 Bin Zhao, Yue Liu, Oliver He CTNNB CTNNB1 Ensembl:ENSG00000168036 GO_0000122 (EC: IBA); GO_0000578 (EC: IBA); GO_0000922 (EC: IEA); GO_0001102 (EC: IPI, PMID: 19443654); GO_0001569 (EC: IBA); GO_0001569 (EC: IC); GO_0001658 (EC: IBA); GO_0001701 (EC: IEA); GO_0001702 (EC: IBA); GO_0001708 (EC: IEA); GO_0001711 (EC: IBA); GO_0001764 (EC: IEA); GO_0001837 (EC: TAS, PMID: 14679171); GO_0001840 (EC: IEA); GO_0001889 (EC: IBA); GO_0002052 (EC: IEA); GO_0002053 (EC: IEA); GO_0002089 (EC: IEA); GO_0003136 (EC: IBA); GO_0003266 (EC: IEA); GO_0003337 (EC: IBA); GO_0003682 (EC: IEA); GO_0003690 (EC: IEA); GO_0003700 (EC: IEA); GO_0003713 (EC: IDA, PMID: 11751639); GO_0003713 (EC: IMP, PMID: 12949260); GO_0004871 (EC: NAS, PMID: 10192393); GO_0005198 (EC: IBA); GO_0005515 (EC: IPI, PMID: 10773885); GO_0005634 (EC: IDA, PMID: 10980594); GO_0005654 (EC: TAS); GO_0005667 (EC: IDA, PMID: 11751639); GO_0005737 (EC: IDA, PMID: 11793365); GO_0005813 (EC: IDA, PMID: 18086858); GO_0005829 (EC: IDA, PMID: 10980594); GO_0005829 (EC: TAS); GO_0005886 (EC: IDA); GO_0005911 (EC: IDA, PMID: 19151727); GO_0005912 (EC: IDA, PMID: 16858403); GO_0005913 (EC: IDA, PMID: 10403777); GO_0005915 (EC: IBA); GO_0005916 (EC: IBA); GO_0005938 (EC: IDA, PMID: 19038973); GO_0006351 (EC: IEA); GO_0006915 (EC: TAS); GO_0006921 (EC: TAS); GO_0007016 (EC: IBA); GO_0007155 (EC: IMP, PMID: 19101069); GO_0007160 (EC: IBA); GO_0007398 (EC: IBA); GO_0007403 (EC: IBA); GO_0007494 (EC: IEA); GO_0008022 (EC: IPI, PMID: 10773885); GO_0008134 (EC: IPI); GO_0008134 (EC: TAS, PMID: 16344550); GO_0008285 (EC: IDA, PMID: 12970740); GO_0009898 (EC: IBA); GO_0009948 (EC: IEA); GO_0009950 (EC: IBA); GO_0009954 (EC: IBA); GO_0010909 (EC: IMP, PMID: 15853773); GO_0014010 (EC: IBA); GO_0016020 (EC: ISS); GO_0016055 (EC: IDA, PMID: 10644691); GO_0016323 (EC: IEA); GO_0016328 (EC: IDA, PMID: 12072559); GO_0016337 (EC: IMP, PMID: 18593713); GO_0016342 (EC: IDA, PMID: 18593713); GO_0019899 (EC: IPI, PMID: 18356165); GO_0019900 (EC: IPI, PMID: 8638126); GO_0019901 (EC: IBA); GO_0019903 (EC: IPI, PMID: 16574648); GO_0021819 (EC: IEA); GO_0022009 (EC: IBA); GO_0030018 (EC: IBA); GO_0030027 (EC: IBA); GO_0030054 (EC: IDA, PMID: 19038973); GO_0030054 (EC: TAS, PMID: 17047063); GO_0030057 (EC: IBA); GO_0030316 (EC: IEA); GO_0030326 (EC: IBA); GO_0030331 (EC: IPI, PMID: 15304487); GO_0030521 (EC: NAS, PMID: 15572661); GO_0030539 (EC: IBA); GO_0030877 (EC: IDA, PMID: 16188939); GO_0030902 (EC: IBA); GO_0030997 (EC: IDA, PMID: 18086858); GO_0031016 (EC: IBA); GO_0031069 (EC: IBA); GO_0031528 (EC: IBA); GO_0031641 (EC: IEA); GO_0032331 (EC: IBA); GO_0032355 (EC: IDA, PMID: 15304487); GO_0032403 (EC: IEA); GO_0032481 (EC: TAS); GO_0032993 (EC: IDA, PMID: 10825188); GO_0033077 (EC: IBA); GO_0033234 (EC: IDA); GO_0034097 (EC: IEA); GO_0034333 (EC: IMP); GO_0034394 (EC: IMP); GO_0034750 (EC: IEA); GO_0035050 (EC: IEA); GO_0035112 (EC: IEA); GO_0035115 (EC: IEA); GO_0035116 (EC: IEA); GO_0035255 (EC: IEA); GO_0035257 (EC: IPI, PMID: 12799378); GO_0035257 (EC: TAS, PMID: 16344550); GO_0035315 (EC: TAS, PMID: 19251162); GO_0036023 (EC: ISS); GO_0042129 (EC: IBA); GO_0042475 (EC: IBA); GO_0042493 (EC: IEP, PMID: 18291362); GO_0042692 (EC: TAS); GO_0042733 (EC: IEA); GO_0043065 (EC: IDA, PMID: 12970740); GO_0043123 (EC: IBA); GO_0043198 (EC: IBA); GO_0043410 (EC: IBA); GO_0043587 (EC: IBA); GO_0044212 (EC: IDA, PMID: 18193033); GO_0044325 (EC: IPI, PMID: 19996314); GO_0044334 (EC: IMP, PMID: 17072303); GO_0044336 (EC: IMP, PMID: 12154096); GO_0045087 (EC: TAS); GO_0045177 (EC: IEA); GO_0045202 (EC: IBA); GO_0045294 (EC: IPI, PMID: 7650039); GO_0045296 (EC: IPI, PMID: 12734196); GO_0045445 (EC: IEA); GO_0045453 (EC: IEA); GO_0045603 (EC: IEA); GO_0045669 (EC: IBA); GO_0045671 (EC: IBA); GO_0045743 (EC: IBA); GO_0045765 (EC: TAS, PMID: 18756595); GO_0045892 (EC: IMP, PMID: 19653274); GO_0045893 (EC: IDA, PMID: 12970740); GO_0045893 (EC: IMP, PMID: 12949260); GO_0045944 (EC: IDA, PMID: 11751639); GO_0045944 (EC: IMP, PMID: 15592430); GO_0046332 (EC: IPI, PMID: 18593713); GO_0046686 (EC: IEA); GO_0048145 (EC: TAS, PMID: 16858403); GO_0048262 (EC: IBA); GO_0048469 (EC: IEA); GO_0048471 (EC: IDA, PMID: 19038973); GO_0048489 (EC: IBA); GO_0048538 (EC: IBA); GO_0048599 (EC: IBA); GO_0048617 (EC: IBA); GO_0048660 (EC: IMP, PMID: 17122440); GO_0048715 (EC: IEA); GO_0050681 (EC: NAS, PMID: 15572661); GO_0050808 (EC: IBA); GO_0051145 (EC: IBA); GO_0051149 (EC: TAS); GO_0051291 (EC: IEA); GO_0060066 (EC: IEA); GO_0060070 (EC: IDA, PMID: 12937339); GO_0060440 (EC: IBA); GO_0060441 (EC: IEA); GO_0060479 (EC: IBA); GO_0060484 (EC: IBA); GO_0060492 (EC: IBA); GO_0060742 (EC: IEA); GO_0060769 (EC: IBA); GO_0060789 (EC: IBA); GO_0060916 (EC: IBA); GO_0061047 (EC: IBA); GO_0061154 (EC: IMP); GO_0061198 (EC: IEA); GO_0061324 (EC: ISS); GO_0070062 (EC: IDA, PMID: 19199708); GO_0070369 (EC: IDA, PMID: 9065401); GO_0070411 (EC: IPI, PMID: 18593713); GO_0070412 (EC: IPI); GO_0070491 (EC: IEA); GO_0070602 (EC: IMP); GO_0071260 (EC: IEA); GO_0071363 (EC: IMP, PMID: 16858403); GO_0071681 (EC: IDA, PMID: 10868478); GO_0071944 (EC: IDA, PMID: 19038973); GO_0072033 (EC: IBA); GO_0072053 (EC: IBA); GO_0072054 (EC: IBA); GO_0072079 (EC: IBA); GO_0072182 (EC: ISS); GO_0090279 (EC: IDA, PMID: 19996314); GO_2000008 (EC: IDA, PMID: 19996314); GO_2000017 (EC: IEA); GO_2001234 (EC: IEA) HGNC:2514 HPRD:00286 MIM:116806 MRD19 OK/SW-cl.35 Official from a nomenclature committee PMID: 7542250; 7642713; 7650039; 7702605; 7706414; 7736793; 7806582; 7829088; 7876318; 7890674; 7954478; 8227214; 8259519; 8638126; 8663237; 8757136; 8838805; 9054423; 9065401; 9065402; 9110993; 9139698; 9214391; 9233779; 9245795; 9286858; 9294210; 9312064; 9348292; 9405455; 9419974; 9434630; 9482734; 9500465; 9512503; 9521872; 9535896; 9545347; 9566905; 9601641; 9632714; 9734785; 9738936; 9751710; 9762469; 9819408; 9823329; 9843967; 9852041; 9927029; 9971746; 9990852; 10021369; 10023660; 10026156; 10029089; 10037471; 10074433; 10092585; 10187801; 10192393; 10207020; 10228155; 10321728; 10330181; 10330403; 10341227; 10381631; 10391090; 10398436; 10403777; 10435629; 10462524; 10477752; 10488109; 10491393; 10545404; 10620020; 10635315; 10644691; 10655994; 10666372; 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21195420; 21196339; 21207157; 21215703; 21225227; 21239045; 21240516; 21254927; 21259057; 21284870; 21292023; 21297666; 21297984; 21299429; 21299609; 21303971; 21317931; 21323417; 21325624; 21331989; 21336184; 21344156; 21350711; 21352379; 21354309; 21355306; 21357396; 21362399; 21368895; 21369691; 21378377; 21383695; 21384147; 21385933; 21391741; 21411632; 21422242; 21447180; 21448924; 21454805; 21457159; 21466614; 21479203; 21494638; 21502434; 21505183; 21506126; 21521850; 21524889; 21527747; 21531001; 21532622; 21538055; 21545903; 21562161; 21565795; 21569306; 21575861; 21577209; 21584489; 21602666; 21610149; 21612684; 21613219; 21617231; 21622533; 21625458; 21638320; 21643019; 21649463; 21661417; 21664290; 21665151; 21670201; 21671177; 21677537; 21678082; 21691299; 21704588; 21726809; 21743491; 21744004; 21747169; 21757651; 21761366; 21764279; 21769465; 21775056; 21781302; 21781452; 21781455; 21792768; 21803632; 21807967; 21821917; 21822311; 21822615; 21832049; 21836063; 21841793; 21849806; 21852086; 21852538; 21858114; 21858154; 21860425; 21875946; 21880956; 21881488; 21881870; 21884207; 21884214; 21890473; 21894439; 21901162; 21906983; 21908588; 21928230; 21935866; 21949247; 21949397; 21952639; 21963094; 21963849; 21965288; 21975680; 21980461; 21986938; 21987572; 21992464; 21993766; 21994129; 21999200; 22007144; 22014042; 22014044; 22017875; 22020335; 22022540; 22023520; 22024040; 22028615; 22034877; 22041457; 22049531; 22053859; 22053931; 22056988; 22080244; 22080605; 22081130; 22083140; 22083958; 22086512; 22093097; 22095489; 22095947; 22099930; 22100495; 22110128; 22110662; 22115830; 22126602; 22133004; 22135721; 22139084; 22142772; 22152854; 22154485; 22155184; 22156527; 22158051; 22158061; 22166221; 22174153; 22180573; 22187462; 22194818; 22198706; 22199277; 22202456; 22209340; 22211293; 22213192; 22221700; 22230368; 22231735; 22232518; 22234184; 22234612; 22241478; 22246236; 22276175; 22281980; 22287118; 22298898; 22298956; 22300273; 22303878; 22304920; 22307379; 22328737; 22333550; 22337891; 22350414; 22369945; 22372443; 22383975; 22391162; 22392736; 22392999; 22406377; 22407433; 22415718; 22425263; 22427053; 22438981; 22454041; 22455883; 22456437; 22458737; 22459450; 22460269; 22466651; 22469663; 22475572; 22494971; 22504420; 22505738; 22507326; 22509309; 22509369; 22516360; 22524844; 22526905; 22535304; 22540002; 22544606; 22550094; 22560296; 22576020; 22576689; 22579815; 22609776; 22613727; 22613765; 22614067; 22622416; 22630347; 22647378; 22653977; 22665063; 22668871; 22674979; 22682247; 22685558; 22692453; 22699938; 22702043; 22704062; 22705350; 22713211; 22715382; 22721621; 22723415; 22728435; 22730322; 22734943; 22739727; 22751121; 22766303; 22766794; 22773696; 22777005; 22800756; 22805760; 22815287; 22823957; 22848100; 22855334; 22864797; 22865883; 22905262; 22908324; 22912335; 22914623; 22915253; 22918686; 22919265; 22938416; 22944692; 22945641; 22946055; 22952611; 22955108; 22956765; 22958082; 23009572; 23020601; 23029025; 23030478; 23032819; 23042269; 23056515; 23065461; 23067217; 23068095; 23068607; 23086933; 23094073; 23099107; 23114888; 23117548; 23138978; 23142810; 23152409; 23159080; 23168683; 23174221; 23208497; 23211630; 23216017; 23220849; 23221384; 23222438; 23233089; 23235344; 23240619; 23243000; 23243217; 23245941; 23246962; 23252868; 23261982; 23268410; 23269799; 23273980; 23274133; 23275444; 23280187; 23292837; 23295859; 23301872; 23302090; 23307470; 23316072; 23317545; 23321667; 23325790; 23333633; 23337059; 23339186; 23349466; 23349811; 23355201; 23375645; 23405266; 23409032; 23437103; 23447569; 23452984; 23483729; 23489693; 23490077; 23499736; 23516071; 23516639; 23525311; 23539445; 23559415; 23559584; 23576562; 23578392; 23582741; 23583404; 23583669; 23592333; 23598517; 23602568; 23603171; 23613467; 23629955; 23640056; 23661344; 23667531; 23671189; 23671587; 23677639; 23690607; 23691015; 23704310; 23707389; 23717499; 23718855; 23727580; 23743566; 23744067; 23767917; 23784889; 23785285; 23787212; 23790492; 23796566; 23811937; 23826417; 23836524; 23840677; 23840886; 23844214; 23844215; 23887712; 23900566; 23913621; 23936352; 23950177; 23954158; 23959799; 23967107; 23983127; 23999248; 24003087; 24011952; 24019458; 24021281; 24042437; 24055345; 24061522; 24071572; 24096034; 24123033; 24127488; 24129577; 24145651; 24157255; 24158438; 24182564; 24255178; 24261884; 24276407; 24317174; 24342833; 24355586; 24413733; 24449884; 24469040; 24501426 Vega:OTTHUMG00000131393 WEB: http://www.ncbi.nlm.nih.gov/gene armadillo catenin (cadherin-associated protein), beta 1, 88kDa catenin (cadherin-associated protein), beta 1, 88kDa protein-coding GBA 1 1q21 20140408 2629 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000177628 GBA GBA1 GCB GLUC GO_0004348 (EC: IDA, PMID: 19279011); GO_0005102 (EC: ISS, PMID: 18022370); GO_0005515 (EC: IPI); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005765 (EC: ISS, PMID: 18022370); GO_0005765 (EC: TAS); GO_0005975 (EC: IEA); GO_0006665 (EC: TAS); GO_0006680 (EC: IMP, PMID: 19279011); GO_0006687 (EC: TAS); GO_0008219 (EC: IEA); GO_0009268 (EC: IEA); GO_0023021 (EC: IMP, PMID: 19279008); GO_0032715 (EC: IDA, PMID: 19279008); GO_0033561 (EC: IEA); GO_0033574 (EC: IEA); GO_0035307 (EC: IMP, PMID: 19279008); GO_0043202 (EC: ISS, PMID: 18022370); GO_0043407 (EC: IMP, PMID: 19279008); GO_0043589 (EC: IEA); GO_0043627 (EC: IEA); GO_0044281 (EC: TAS); GO_0046512 (EC: IMP, PMID: 19279011); GO_0046513 (EC: IMP, PMID: 19279011); GO_0050728 (EC: IC, PMID: 19279008); GO_0051384 (EC: IEA); GO_0071356 (EC: IMP, PMID: 19279008); GO_0097066 (EC: IEA) HGNC:4177 HPRD:06973 MIM:606463 Official from a nomenclature committee PMID: 1572652; 1594045; 1698821; 1899336; 1972019; 1974409; 2295698; 2438102; 2914709; 3001061; 3353383; 3359914; 3456607; 3472750; 3547401; 3687939; 3863141; 3864160; 4003396; 6091633; 6455062; 6816512; 6885065; 7613473; 7627184; 7627192; 7916532; 8076951; 8112750; 8118460; 8188616; 8294033; 8432537; 8694790; 8780099; 8790604; 8829654; 8829663; 8889578; 8889591; 8907609; 8937765; 9040001; 9061570; 9153297; 9182788; 9217217; 9225972; 9279145; 9331372; 9516376; 9554454; 9554746; 9637431; 9650766; 9683600; 9705233; 9851895; 10079102; 10340647; 10352942; 10360404; 10447266; 10527671; 10649495; 10744424; 11584048; 11708865; 11933202; 12048121; 12107439; 12173027; 12359135; 12360742; 12360744; 12434014; 12477932; 12482401; 12587096; 12667141; 12754519; 12792654; 12803123; 12972024; 14728994; 14757764; 14994233; 15146461; 15322500; 15489334; 15517591; 15517592; 15525722; 15591280; 15610510; 15857183; 15954102; 15967693; 15982918; 16086325; 16148263; 16223608; 16329099; 16344560; 16476943; 16781064; 16790605; 16830265; 16861620; 16981045; 16996765; 17187079; 17427031; 17462935; 17574891; 17620502; 17689991; 17702778; 17703984; 17713797; 17875915; 17897319; 17996473; 18022370; 18030725; 18074383; 18078074; 18160183; 18178337; 18264947; 18313951; 18332251; 18338393; 18429048; 18434642; 18541113; 18562733; 18586535; 18586596; 18619939; 18674488; 18829375; 18852351; 18979180; 18987351; 19224617; 19260119; 19279008; 19279011; 19286695; 19332698; 19383421; 19394250; 19425057; 19433656; 19433657; 19458969; 19459886; 19460752; 19527940; 19578116; 19846850; 19882201; 19913121; 19945510; 19953087; 20004703; 20053430; 20131388; 20148966; 20177787; 20182943; 20223112; 20301387; 20301402; 20301446; 20425034; 20528910; 20580583; 20628086; 20643691; 20700730; 20729108; 20816920; 20947659; 20971030; 20980259; 20980263; 21087600; 21098288; 21221911; 21242499; 21338444; 21569768; 21621439; 21633851; 21653695; 21674799; 21700325; 21723784; 21734182; 21742527; 21745757; 21831682; 21856586; 21889374; 21915911; 21963094; 22001711; 22021190; 22160715; 22167193; 22173904; 22192918; 22220748; 22227325; 22268729; 22282650; 22344629; 22352271; 22387070; 22427207; 22442429; 22451204; 22493294; 22542428; 22658918; 22659419; 22797727; 22803570; 22812582; 22935721; 22968580; 23034917; 23035075; 23062841; 23079555; 23151436; 23225227; 23227814; 23255161; 23413260; 23418083; 23426826; 23434032; 23490118; 23580063; 23588557; 23635853; 23639447; 23699752; 23719189; 24070323; 24351928 Vega:OTTHUMG00000035841 WEB: http://www.ncbi.nlm.nih.gov/gene glucosidase, beta, acid glucosidase, beta, acid protein-coding HNF4A 20 20140408 20q13.12 3172 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000101076 GO_0001077 (EC: ISS); GO_0001102 (EC: ISS); GO_0003677 (EC: IDA, PMID: 10551874); GO_0003700 (EC: IDA, PMID: 10330009); GO_0003705 (EC: IEA); GO_0003707 (EC: IEA); GO_0004879 (EC: IEA); GO_0005102 (EC: IDA, PMID: 12220494); GO_0005504 (EC: IDA, PMID: 12220494); GO_0005515 (EC: IPI, PMID: 16488887); GO_0005634 (EC: IDA, PMID: 14563941); GO_0005654 (EC: TAS); GO_0005737 (EC: IDA, PMID: 14563941); GO_0006357 (EC: IDA, PMID: 10330009); GO_0006357 (EC: IMP, PMID: 18163890); GO_0006367 (EC: TAS); GO_0006591 (EC: IMP, PMID: 17827783); GO_0006629 (EC: IEA); GO_0006805 (EC: IMP, PMID: 17827783); GO_0007548 (EC: IEA); GO_0007596 (EC: IDA, PMID: 12911579); GO_0008270 (EC: IEA); GO_0008285 (EC: IMP, PMID: 18163890); GO_0009749 (EC: ISS); GO_0010467 (EC: TAS); GO_0010470 (EC: IEA); GO_0019216 (EC: IDA, PMID: 10551874); GO_0023019 (EC: IEA); GO_0030308 (EC: IMP, PMID: 18163890); GO_0031018 (EC: TAS); GO_0042593 (EC: ISS); GO_0042803 (EC: IDA, PMID: 12220494); GO_0043565 (EC: IEA); GO_0044212 (EC: IDA, PMID: 16488887); GO_0045893 (EC: IDA, PMID: 16488887); GO_0045944 (EC: IDA, PMID: 7615825); GO_0045944 (EC: IMP, PMID: 17827783); GO_0050796 (EC: ISS); GO_0055088 (EC: IMP, PMID: 17827783); GO_0055091 (EC: ISS); GO_0060395 (EC: IEA); GO_0060398 (EC: NAS, PMID: 17991764); GO_0070328 (EC: ISS); GO_2000189 (EC: ISS) HGNC:5024 HNF4 HNF4A HNF4a7 HNF4a8 HNF4a9 HNF4alpha HPRD:02612 MIM:600281 MODY MODY1 NR2A1 NR2A21 Official from a nomenclature committee PMID: 1899928; 7568236; 7615825; 7651430; 7926813; 8622695; 8945471; 8964514; 9048927; 9115274; 9243109; 9267996; 9294105; 9313765; 9371825; 9434765; 9449683; 9717844; 9792714; 9792724; 9795230; 9812974; 10085149; 10330009; 10551874; 10594021; 10609119; 10652338; 10737800; 10786636; 10882110; 10995777; 11229886; 11549316; 11590126; 11717395; 11733490; 11741883; 11772903; 11780052; 11811951; 11818510; 11834723; 11916906; 11994285; 12036449; 12050210; 12083813; 12086970; 12089346; 12101254; 12110948; 12133007; 12203996; 12205093; 12220494; 12235114; 12413008; 12477932; 12504020; 12519792; 12522137; 12544512; 12551987; 12627330; 12631740; 12669197; 12697672; 12701690; 12740371; 12829997; 12855700; 12911579; 12944908; 14551916; 14563941; 14654354; 14702039; 14722127; 14988562; 15047632; 15047633; 15123688; 15194767; 15281001; 15322103; 15337761; 15342556; 15358161; 15470081; 15504983; 15519277; 15520459; 15547294; 15561969; 15604093; 15616580; 15651981; 15660729; 15728204; 15734869; 15735891; 15735892; 15744310; 15752752; 15793260; 15794920; 15796896; 15826954; 15830177; 15831710; 15919766; 15928245; 15933212; 15983230; 16007190; 16051671; 16186411; 16223942; 16338932; 16351573; 16488887; 16502298; 16523192; 16562587; 16584384; 16644680; 16712791; 16731855; 16731861; 16752173; 16771709; 16804065; 16838170; 16873704; 16882880; 16883527; 16893891; 16929032; 16936201; 16946562; 16955255; 16978381; 16980607; 17007050; 17022998; 17052457; 17259399; 17264800; 17291450; 17300672; 17317687; 17327436; 17343826; 17344191; 17353931; 17393984; 17403900; 17407387; 17464991; 17466274; 17563455; 17574576; 17576804; 17601994; 17636037; 17764444; 17785436; 17805472; 17827402; 17827783; 17876342; 17885207; 17891372; 17894829; 17895379; 17920062; 17923767; 17932483; 17958743; 17965524; 17991764; 17992261; 18028455; 18029348; 18056193; 18162503; 18163890; 18184923; 18199540; 18234786; 18268044; 18305369; 18305375; 18332101; 18346225; 18356407; 18391435; 18395097; 18426912; 18498634; 18513187; 18513302; 18552123; 18561282; 18602983; 18654034; 18660489; 18666237; 18728231; 18765665; 18805788; 18811724; 18829458; 18844932; 18988528; 19048623; 19060906; 19115260; 19147806; 19154258; 19179483; 19188435; 19228875; 19228884; 19302415; 19336534; 19353766; 19389810; 19406499; 19435525; 19454287; 19467232; 19549071; 19563409; 19575803; 19578796; 19651776; 19740748; 19748811; 19761587; 19805548; 19846556; 19913121; 19915572; 19924231; 19934400; 19948975; 19966299; 20003313; 20079163; 20086032; 20158877; 20164212; 20167659; 20211142; 20301549; 20308432; 20361036; 20371703; 20375098; 20379614; 20384434; 20463007; 20516075; 20546279; 20558840; 20576917; 20622021; 20628086; 20670916; 20682687; 20684663; 20686565; 20705777; 20714348; 20735474; 20863361; 20871093; 20878384; 20926756; 20931292; 20976847; 21047794; 21062274; 21062980; 21292004; 21300955; 21352552; 21384409; 21442235; 21493011; 21494118; 21618351; 21633728; 21646355; 21683639; 21708125; 21725089; 21733563; 21744425; 21760481; 21799848; 21814221; 21831733; 21852396; 21874001; 21922456; 21983932; 21988832; 22009745; 22060211; 22068426; 22140441; 22153071; 22155889; 22158537; 22197810; 22240483; 22282358; 22308320; 22333269; 22357705; 22383578; 22432108; 22505616; 22628013; 22791717; 22802087; 22902540; 22914433; 22939635; 22952853; 22960426; 23038264; 23052196; 23108025; 23128233; 23268925; 23292115; 23307400; 23348805; 23628799; 23652628; 23775631; 23803251; 23874642; 23878349 RP5-1013A22.1 TCF TCF14 Vega:OTTHUMG00000032531 WEB: http://www.ncbi.nlm.nih.gov/gene hepatocyte nuclear factor 4, alpha hepatocyte nuclear factor 4, alpha protein-coding LRP2 2 20140408 2q31.1 4036 9606 Bin Zhao, Yue Liu, Oliver He DBS Ensembl:ENSG00000081479 GO_0001523 (EC: TAS); GO_0005509 (EC: IEA); GO_0005515 (EC: IPI, PMID: 14528014); GO_0005764 (EC: TAS, PMID: 7768901); GO_0005765 (EC: IDA, PMID: 17897319); GO_0005768 (EC: IEA); GO_0005783 (EC: IEA); GO_0005794 (EC: IEA); GO_0005886 (EC: TAS); GO_0005905 (EC: IEA); GO_0006486 (EC: TAS, PMID: 2786251); GO_0006629 (EC: TAS, PMID: 7768901); GO_0006897 (EC: TAS, PMID: 7768901); GO_0006898 (EC: IEA); GO_0007603 (EC: TAS); GO_0008202 (EC: TAS); GO_0008283 (EC: IEA); GO_0016021 (EC: IEA); GO_0016324 (EC: ISS); GO_0017124 (EC: IEA); GO_0030139 (EC: IEA); GO_0030900 (EC: IEA); GO_0031526 (EC: IEA); GO_0042359 (EC: TAS); GO_0043235 (EC: IDA); GO_0044281 (EC: TAS); GO_0070062 (EC: IDA, PMID: 19056867) GP330 HGNC:6694 HPRD:02509 LRP2 MIM:600073 Official from a nomenclature committee PMID: 1382088; 2786251; 7512726; 7579068; 7657789; 7686151; 7768901; 7775583; 7959795; 8187828; 8344937; 8706697; 8710893; 8898021; 9071320; 9228033; 9334227; 9492085; 9655248; 9727058; 9773776; 9837937; 10073957; 10203351; 10330424; 10364184; 10753646; 10769163; 10772929; 10827173; 10982792; 11095640; 11158855; 11274227; 11278724; 11421580; 11595644; 11717447; 11912251; 11994745; 12107412; 12169628; 12508107; 12707383; 12713445; 12723989; 12768436; 12879166; 14528014; 14657389; 15134832; 15583024; 15670845; 15951480; 16174284; 16344560; 16713569; 16828734; 16908842; 17260971; 17457342; 17474147; 17555532; 17632512; 17897319; 17979745; 18070591; 18174661; 18448595; 18559602; 18685438; 18791690; 19056867; 19913121; 19940034; 20031551; 20038220; 20052685; 20139978; 20301732; 20379614; 20468071; 20628086; 20800603; 20971101; 21079607; 21104416; 21595846; 22170372; 22174918; 22437417; 22565184; 22578327; 22649097; 23274376; 23275343; 23673647; 23909735; 24197071 Vega:OTTHUMG00000132179 WEB: http://www.ncbi.nlm.nih.gov/gene low density lipoprotein receptor-related protein 2 low density lipoprotein receptor-related protein 2 protein-coding NEUROG1 20140408 4762 5 5q23-q31 9606 AKA Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000181965 GO_0000989 (EC: ISS); GO_0003677 (EC: ISS); GO_0003682 (EC: ISS); GO_0003700 (EC: TAS, PMID: 8816493); GO_0005634 (EC: IEA); GO_0006351 (EC: IEA); GO_0006357 (EC: TAS, PMID: 8816493); GO_0007399 (EC: TAS, PMID: 8816493); GO_0030182 (EC: IEA); GO_0031536 (EC: IEA); GO_0042472 (EC: IEA); GO_0043204 (EC: IEA); GO_0045165 (EC: IEA); GO_0045666 (EC: ISS); GO_0045944 (EC: ISS); GO_0046983 (EC: IEA); GO_0051091 (EC: ISS); GO_0070888 (EC: ISS) HGNC:7764 HPRD:03430 MIM:601726 Math4C NEUROD3 NEUROG1 Official from a nomenclature committee PMID: 8816493; 9119405; 11239394; 11732772; 12477932; 12526089; 15489334; 17044100; 18053270; 18799289; 19086053; 19813087; 20102160; 20211142; 21326223; 21697133; 23034738; 23419067 Vega:OTTHUMG00000129138 WEB: http://www.ncbi.nlm.nih.gov/gene bHLHa6 neurogenin 1 neurogenin 1 ngn1 protein-coding POU5F1 20140408 5460 6 6p21.31 9606 Bin Zhao, Yue Liu, Oliver He DADB-104B20.2 Ensembl:ENSG00000204531 GO_0000981 (EC: ISS); GO_0001714 (EC: IDA); GO_0001824 (EC: ISS); GO_0003130 (EC: IMP, PMID: 19736317); GO_0003677 (EC: IDA, PMID: 16153702); GO_0003700 (EC: IDA, PMID: 16153702); GO_0005515 (EC: IPI, PMID: 11099378); GO_0005634 (EC: IC, PMID: 16153702); GO_0005634 (EC: IDA, PMID: 18000303); GO_0005654 (EC: IDA); GO_0005667 (EC: IDA, PMID: 19736317); GO_0005737 (EC: IDA, PMID: 18281244); GO_0005829 (EC: IDA, PMID: 18000303); GO_0006355 (EC: IDA, PMID: 16153702); GO_0006366 (EC: ISS); GO_0008134 (EC: IPI, PMID: 19736317); GO_0009611 (EC: IEP, PMID: 17982423); GO_0009653 (EC: TAS, PMID: 9814708); GO_0009786 (EC: ISS); GO_0010468 (EC: IMP, PMID: 18388306); GO_0031625 (EC: IPI, PMID: 19274063); GO_0035019 (EC: IDA, PMID: 19409607); GO_0035019 (EC: IMP, PMID: 18388306); GO_0035198 (EC: IDA, PMID: 18710938); GO_0035413 (EC: IDA, PMID: 19736317); GO_0042789 (EC: ISS); GO_0043565 (EC: IDA); GO_0044212 (EC: IDA, PMID: 19736317); GO_0044822 (EC: IDA); GO_0045944 (EC: IDA, PMID: 19736317); GO_0060391 (EC: IDA, PMID: 19736317); GO_0060795 (EC: IMP, PMID: 19736317); GO_0060913 (EC: IDA, PMID: 19736317); GO_0060965 (EC: IMP, PMID: 19409607); GO_0090081 (EC: IMP, PMID: 19736317); GO_0090308 (EC: IDA, PMID: 19736317) HGNC:9221 HPRD:01252 MIM:164177 OCT3 OCT4 OTF-3 OTF3 OTF4 Oct-3 Oct-4 Official from a nomenclature committee PMID: 1408763; 1723621; 7908264; 8088794; 8500351; 8567814; 8889549; 9368058; 9814708; 10742100; 11096094; 11099378; 11689681; 11891324; 12477932; 12653732; 12727846; 12841847; 12923055; 15047715; 15105401; 15342930; 15467907; 15513931; 15615706; 15625129; 15695770; 15729702; 15749924; 15790780; 15917470; 16149048; 16153702; 16229821; 16421218; 16557044; 16582099; 16702430; 16892178; 16916925; 16951404; 17011492; 17013377; 17068183; 17093407; 17136117; 17205510; 17211834; 17226773; 17245123; 17273778; 17314032; 17314394; 17379765; 17390031; 17409736; 17413979; 17506876; 17525163; 17549357; 17554336; 17573914; 17682839; 17761754; 17923501; 17959850; 17982423; 18000303; 18029452; 18032701; 18088417; 18157115; 18191611; 18199879; 18231740; 18254969; 18269588; 18281244; 18295396; 18338169; 18339675; 18366076; 18388306; 18439155; 18440631; 18467432; 18593985; 18594515; 18612434; 18617685; 18676852; 18687992; 18710938; 18757296; 18765667; 18787205; 18806776; 18810488; 18818365; 18946985; 18957414; 18985733; 19023518; 19058139; 19060217; 19102659; 19103427; 19126554; 19170206; 19171782; 19203577; 19224167; 19224238; 19271143; 19274063; 19274762; 19327014; 19347886; 19350677; 19383152; 19394308; 19396148; 19409607; 19414369; 19438894; 19445899; 19458492; 19483629; 19489092; 19528230; 19536159; 19549847; 19559696; 19657699; 19696409; 19718018; 19736317; 19751112; 19777066; 19816951; 19851445; 19884257; 19898493; 19966271; 19968627; 19969351; 20027182; 20034424; 20038322; 20051954; 20054811; 20074550; 20101213; 20103622; 20123703; 20139178; 20171362; 20173672; 20203285; 20224565; 20224970; 20230781; 20333750; 20347080; 20356403; 20379614; 20404147; 20412569; 20412747; 20433421; 20458727; 20462980; 20477760; 20497257; 20505756; 20505821; 20508149; 20510497; 20526341; 20587610; 20594032; 20647538; 20662612; 20698766; 20721963; 20736927; 20805580; 20818602; 20824712; 20858707; 20879854; 20881960; 20937145; 20942235; 20953172; 20958186; 20981110; 21048921; 21107090; 21135096; 21151097; 21151833; 21159654; 21166886; 21227461; 21262915; 21273125; 21301344; 21365617; 21376027; 21394007; 21403679; 21419292; 21477851; 21479367; 21480394; 21496429; 21533858; 21547540; 21559451; 21602143; 21602158; 21631526; 21674242; 21684074; 21692598; 21725800; 21798248; 21801394; 21804543; 21844352; 21852325; 21868340; 21900452; 21912425; 21938739; 21946204; 21947321; 21951846; 21960344; 21962512; 21987575; 22014056; 22037460; 22160855; 22207173; 22247013; 22252524; 22286766; 22300949; 22301499; 22311737; 22340650; 22363145; 22378186; 22387393; 22392999; 22393366; 22396540; 22429998; 22446105; 22448662; 22474382; 22482508; 22506928; 22528324; 22576801; 22588915; 22613719; 22727933; 22743827; 22777760; 22795133; 22824146; 22832160; 22844522; 22847005; 22901285; 22903480; 22914767; 22922943; 22944295; 23000165; 23002208; 23024368; 23041284; 23052207; 23076549; 23088399; 23136034; 23185410; 23211052; 23213213; 23255053; 23276226; 23279472; 23290742; 23302226; 23307247; 23314702; 23340171; 23349823; 23391989; 23433354; 23438193; 23499384; 23525564; 23539445; 23541921; 23545524; 23549118; 23588367; 23594289; 23601300; 23609451; 23613252; 23613880; 23615404; 23636800; 23643069; 23670345; 23736381; 23828673; 23872274; 23928699; 23933063; 23955597; 23984394; 24182453; 24324071 POU class 5 homeobox 1 POU class 5 homeobox 1 POU5F1 Vega:OTTHUMG00000031206 WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding RB1 13 13q14.2 20140408 5925 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000139687 GO_0000075 (EC: TAS, PMID: 10825186); GO_0000082 (EC: TAS); GO_0000083 (EC: TAS, PMID: 19149898); GO_0000278 (EC: TAS); GO_0000785 (EC: TAS, PMID: 3657987); GO_0001047 (EC: IDA, PMID: 15735762); GO_0001102 (EC: IEA); GO_0003677 (EC: TAS, PMID: 3657987); GO_0003700 (EC: TAS, PMID: 3657987); GO_0003713 (EC: NAS, PMID: 15572661); GO_0005515 (EC: IPI, PMID: 10613832); GO_0005634 (EC: IDA, PMID: 17540172); GO_0005654 (EC: TAS); GO_0005819 (EC: IEA); GO_0006338 (EC: TAS, PMID: 19149898); GO_0006351 (EC: IEA); GO_0006469 (EC: IPI, PMID: 9858607); GO_0007050 (EC: TAS, PMID: 19149898); GO_0007070 (EC: TAS, PMID: 19149898); GO_0007093 (EC: TAS, PMID: 9529249); GO_0007265 (EC: IEP, PMID: 9054499); GO_0007346 (EC: IMP); GO_0008134 (EC: IPI, PMID: 16360038); GO_0016032 (EC: IEA); GO_0016514 (EC: TAS, PMID: 19149898); GO_0016605 (EC: IDA, PMID: 9448006); GO_0019900 (EC: IDA, PMID: 16286473); GO_0030521 (EC: NAS, PMID: 15572661); GO_0031134 (EC: IMP); GO_0031175 (EC: IEA); GO_0031625 (EC: IPI, PMID: 10944455); GO_0034088 (EC: IMP); GO_0034349 (EC: IEA); GO_0035189 (EC: TAS, PMID: 19149898); GO_0035914 (EC: IEA); GO_0042551 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16360038); GO_0043353 (EC: IEA); GO_0043433 (EC: TAS, PMID: 9529249); GO_0043550 (EC: IDA, PMID: 16286473); GO_0045445 (EC: IMP, PMID: 15541338); GO_0045651 (EC: IEA); GO_0045842 (EC: IMP); GO_0045879 (EC: IEA); GO_0045892 (EC: IDA, PMID: 10783144); GO_0045892 (EC: TAS, PMID: 19149898); GO_0045893 (EC: NAS, PMID: 15572661); GO_0045944 (EC: IEA); GO_0048565 (EC: IEA); GO_0048667 (EC: IEA); GO_0050680 (EC: IEA); GO_0050681 (EC: NAS, PMID: 15572661); GO_0051146 (EC: IEA); GO_0051219 (EC: IPI, PMID: 16360038); GO_0051402 (EC: IEA); GO_0071459 (EC: IMP); GO_0071922 (EC: IMP); GO_0071930 (EC: IEA); GO_0090230 (EC: TAS); GO_0097284 (EC: IEA); GO_2000134 (EC: TAS, PMID: 19149898) HGNC:9884 HPRD:01574 MIM:614041 OSRC Official from a nomenclature committee PMID: 1352398; 1352883; 1388726; 1532458; 1638634; 1641004; 1756735; 1857421; 2005966; 2594029; 2601691; 2701949; 2717184; 2839300; 3413073; 3480530; 3653883; 3657987; 3823889; 7287000; 7503932; 7525595; 7538672; 7542657; 7558034; 7592647; 7629134; 7664264; 7673249; 7704558; 7724524; 7732011; 7739537; 7756179; 7777526; 7791904; 7795591; 7818556; 7828850; 7838535; 7877691; 7881418; 7902321; 7923370; 7927327; 7935440; 7958924; 8058329; 8152792; 8170997; 8217609; 8230483; 8242749; 8246996; 8255752; 8278403; 8346196; 8346255; 8350924; 8381715; 8384581; 8434021; 8475068; 8490568; 8490963; 8493578; 8552662; 8560263; 8605116; 8626527; 8647086; 8651278; 8657117; 8662825; 8756624; 8756626; 8776589; 8816797; 8816798; 8832394; 8867812; 8870681; 8896460; 8946919; 9003781; 9010216; 9029153; 9053846; 9054499; 9071815; 9125176; 9128241; 9139732; 9140452; 9145110; 9169441; 9178770; 9178893; 9190208; 9199321; 9223517; 9242374; 9256431; 9258347; 9311732; 9312071; 9315635; 9315663; 9343168; 9380698; 9395244; 9400991; 9422723; 9448006; 9453249; 9464540; 9468139; 9468140; 9491888; 9495340; 9501179; 9525916; 9529249; 9545246; 9553123; 9559293; 9566894; 9566959; 9632747; 9632788; 9671498; 9675141; 9697699; 9710587; 9712901; 9721205; 9724731; 9813067; 9819434; 9858607; 9858615; 9885575; 9973307; 9988677; 10022926; 10026157; 10049762; 10078201; 10082561; 10196196; 10197586; 10198259; 10202152; 10207050; 10220405; 10228159; 10321733; 10330166; 10339564; 10353443; 10359315; 10359664; 10376528; 10393912; 10409732; 10446990; 10486249; 10490602; 10491434; 10499802; 10518542; 10523633; 10613832; 10615135; 10644764; 10647931; 10671068; 10702291; 10721693; 10734134; 10748174; 10778858; 10779342; 10779361; 10783144; 10825186; 10850422; 10866689; 10869426; 10888886; 10938106; 10938588; 10944455; 10958676; 11034201; 11042686; 11073989; 11073990; 11085541; 11090181; 11094070; 11113200; 11126356; 11158299; 11162467; 11254678; 11259609; 11268000; 11283269; 11285237; 11350943; 11358960; 11420704; 11433299; 11447271; 11470869; 11484059; 11500496; 11521194; 11524739; 11533237; 11566021; 11568901; 11571651; 11571652; 11583618; 11583987; 11593423; 11596110; 11668642; 11684023; 11748221; 11788883; 11805327; 11832063; 11839806; 11847125; 11896613; 11900540; 11909966; 11931757; 11940667; 11956626; 11960384; 11964378; 11971966; 11997511; 12016586; 12021356; 12032846; 12036888; 12037672; 12054658; 12065415; 12085226; 12096339; 12096344; 12140374; 12145697; 12153616; 12173465; 12190313; 12197776; 12200151; 12210730; 12241561; 12361598; 12362308; 12374284; 12377414; 12391156; 12391839; 12397079; 12401721; 12419581; 12434308; 12439743; 12450794; 12459729; 12461781; 12466551; 12466959; 12473678; 12475961; 12477932; 12479814; 12499093; 12502741; 12507935; 12508351; 12509456; 12519773; 12525503; 12528819; 12532331; 12532471; 12556968; 12569181; 12588990; 12594215; 12598654; 12621062; 12629508; 12676926; 12682072; 12711675; 12757710; 12761493; 12800980; 12809602; 12845674; 12860972; 12891711; 12944478; 12947005; 12949733; 12963846; 12963997; 12970441; 14506250; 14519639; 14527418; 14533007; 14534726; 14555653; 14585976; 14625809; 14627988; 14631100; 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15949438; 15998794; 16007129; 16020958; 16042572; 16127685; 16186801; 16188218; 16205627; 16205633; 16212876; 16214886; 16249186; 16254459; 16269091; 16273238; 16286473; 16303160; 16306221; 16315642; 16326706; 16332962; 16337594; 16343421; 16352731; 16354195; 16360038; 16368535; 16374512; 16388084; 16397580; 16458891; 16464825; 16501607; 16510145; 16570290; 16581787; 16595082; 16600870; 16614728; 16616093; 16616919; 16619045; 16627785; 16645588; 16682076; 16682285; 16685266; 16698799; 16764854; 16766265; 16782892; 16816134; 16824683; 16880741; 16912045; 16912184; 16916716; 16935576; 16936805; 16948516; 16962592; 16964284; 16966377; 16984923; 16985050; 17008050; 17012228; 17015477; 17028578; 17031475; 17043357; 17045206; 17047088; 17053782; 17094467; 17131485; 17145812; 17160137; 17163992; 17182682; 17183714; 17187060; 17216555; 17242198; 17254966; 17274640; 17286450; 17287852; 17297463; 17299438; 17318405; 17332242; 17369289; 17369843; 17380128; 17390023; 17413032; 17428253; 17455244; 17461478; 17490733; 17495525; 17511743; 17517622; 17523078; 17540172; 17549378; 17557897; 17576813; 17597480; 17609271; 17616526; 17616676; 17640669; 17642181; 17652530; 17666433; 17671693; 17686574; 17695524; 17702869; 17704056; 17716930; 17804741; 17827154; 17877762; 17880527; 17900658; 17913706; 17913805; 17916908; 17960112; 17963824; 17972097; 17974914; 17977825; 17991896; 17996702; 18000883; 18048012; 18071317; 18073205; 18181215; 18196971; 18211953; 18216119; 18236071; 18239623; 18259216; 18262051; 18281541; 18294958; 18296270; 18305152; 18306932; 18321963; 18332869; 18348166; 18360108; 18381962; 18383208; 18386058; 18391203; 18431743; 18458534; 18459177; 18477220; 18483265; 18503160; 18546941; 18593909; 18624751; 18628207; 18632617; 18677112; 18677770; 18691182; 18694959; 18697743; 18702872; 18755268; 18766991; 18768921; 18779498; 18782450; 18794045; 18794899; 18801742; 18843795; 18948382; 18950845; 18976938; 19058005; 19081374; 19124506; 19130399; 19137728; 19140325; 19141402; 19144636; 19149898; 19152247; 19160091; 19212661; 19223331; 19225156; 19249677; 19258477; 19279001; 19280657; 19351817; 19383911; 19389926; 19390654; 19421149; 19430707; 19458004; 19465901; 19477924; 19497860; 19524571; 19556322; 19556892; 19588502; 19594747; 19597473; 19631451; 19633425; 19640284; 19648117; 19666944; 19723065; 19738611; 19789190; 19802012; 19817957; 19838216; 19863319; 19880526; 19883508; 19903334; 19919588; 19926638; 19950226; 20003272; 20037816; 20041224; 20059380; 20082263; 20090211; 20100483; 20140018; 20157766; 20195357; 20223825; 20226061; 20226085; 20237430; 20301625; 20336668; 20362553; 20372796; 20372802; 20379614; 20428774; 20435627; 20447117; 20453000; 20499310; 20503270; 20534814; 20551165; 20558744; 20565234; 20594292; 20596833; 20614030; 20627193; 20628002; 20668449; 20680651; 20680693; 20694007; 20705054; 20713352; 20864684; 20870719; 20871633; 20890425; 20924203; 20940255; 20948315; 20948316; 20948989; 20971808; 21042734; 21048031; 21055153; 21085491; 21099110; 21099295; 21119616; 21139044; 21139048; 21148318; 21203526; 21241471; 21253829; 21278246; 21325879; 21329664; 21387305; 21440621; 21447152; 21470325; 21478909; 21491492; 21493295; 21498571; 21518927; 21558273; 21567202; 21593597; 21602887; 21615945; 21654082; 21663659; 21665145; 21674866; 21689726; 21697511; 21725359; 21740549; 21752283; 21763628; 21809081; 21850486; 21855804; 21875955; 21880723; 21890473; 21900881; 21903422; 21906983; 21952639; 21956461; 21980403; 21988832; 21990374; 22078878; 22084214; 22094256; 22112645; 22157621; 22182413; 22184068; 22203219; 22205104; 22219649; 22262832; 22265791; 22299668; 22310660; 22322860; 22333593; 22366686; 22448711; 22493456; 22505724; 22569856; 22576742; 22586056; 22643222; 22644489; 22692183; 22696061; 22698402; 22701041; 22706203; 22730229; 22733537; 22744425; 22768064; 22787429; 22790852; 22802529; 22874878; 22895174; 22939629; 22955272; 22998184; 23000965; 23022380; 23041127; 23059827; 23108995; 23178825; 23232572; 23308053; 23315497; 23339186; 23359405; 23370776; 23408605; 23427156; 23429261; 23441118; 23449391; 23498719; 23532519; 23543736; 23595191; 23602568; 23618872; 23670186; 23707559; 23715307; 23752268; 23788249; 23832541; 23845465; 23853093; 23859194; 23892435; 23900870; 23900873; 23916291; 23936312; 23949216; 23967107; 23969248; 23981575; 24078560; 24103329; 24135281; 24189068; 24231354; 24323028; 24334458; 24335704; 24347427 RB RB1 RP11-174I10.1 Vega:OTTHUMG00000016900 WEB: http://www.ncbi.nlm.nih.gov/gene p105-Rb pRb pp110 protein-coding retinoblastoma 1 retinoblastoma 1 SORT1 1 1p13.3|1p21.3-p13.1 20140408 6272 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000134243 GO_0001503 (EC: IEA); GO_0005515 (EC: IPI, PMID: 10085125); GO_0005765 (EC: IEA); GO_0005769 (EC: IDA, PMID: 11331584); GO_0005789 (EC: IEA); GO_0005794 (EC: IDA, PMID: 11331584); GO_0005886 (EC: IDA, PMID: 11331584); GO_0005886 (EC: NAS, PMID: 14985763); GO_0005905 (EC: IDA, PMID: 11331584); GO_0006895 (EC: IDA, PMID: 11331584); GO_0006897 (EC: IDA, PMID: 11331584); GO_0007186 (EC: IMP, PMID: 18258592); GO_0007218 (EC: IDA, PMID: 9756851); GO_0007275 (EC: IEA); GO_0008333 (EC: IDA, PMID: 11331584); GO_0008625 (EC: IDA, PMID: 14985763); GO_0009986 (EC: IDA, PMID: 10085125); GO_0010008 (EC: IEA); GO_0010465 (EC: IDA, PMID: 14985763); GO_0010468 (EC: IMP, PMID: 18258592); GO_0014902 (EC: IMP, PMID: 18258592); GO_0016021 (EC: IDA, PMID: 15992544); GO_0016023 (EC: IDA, PMID: 9756851); GO_0016050 (EC: IDA, PMID: 15992544); GO_0019899 (EC: IPI, PMID: 10085125); GO_0030136 (EC: IDA, PMID: 11331584); GO_0030140 (EC: IEA); GO_0030379 (EC: IDA, PMID: 9756851); GO_0031965 (EC: IEA); GO_0032509 (EC: IDA, PMID: 11331584); GO_0032580 (EC: IEA); GO_0032868 (EC: IMP, PMID: 15992544); GO_0038180 (EC: IDA, PMID: 14985763); GO_0046323 (EC: IMP, PMID: 15992544); GO_0048011 (EC: IMP, PMID: 14985763); GO_0048227 (EC: IDA, PMID: 11331584); GO_0048406 (EC: IPI, PMID: 14985763); GO_0048471 (EC: IDA, PMID: 11331584); GO_0051005 (EC: IDA, PMID: 10085125) Gp95 HGNC:11186 HPRD:03910 LDLCQ6 MIM:602458 NT3 Official from a nomenclature committee PMID: 9013611; 9305862; 9657377; 9756851; 9927419; 10085125; 10390649; 11257441; 11331584; 11390366; 11499680; 11821067; 11859376; 12209882; 12360476; 12419319; 12477932; 12482870; 12598608; 14657016; 14702039; 14985763; 15313463; 15364913; 15489334; 15930396; 15987945; 15992544; 16087676; 16263699; 16344560; 16710414; 17220298; 17353931; 18029348; 18088323; 18191449; 18193043; 18193044; 18258592; 18603531; 18624930; 18713973; 19060906; 19060910; 19148283; 19198609; 19219422; 19299407; 19322201; 19487539; 19837406; 19875813; 20015111; 20031591; 20036257; 20048080; 20085800; 20159974; 20167577; 20339536; 20383146; 20570916; 20584990; 20613775; 20628624; 20679960; 20686565; 20686566; 20738937; 20816088; 20971364; 21087763; 21139048; 21245145; 21261755; 21378988; 21378990; 21466885; 21521695; 21730062; 21909109; 21963094; 21966426; 22128158; 22256600; 22297619; 22361451; 22418572; 22751103; 22768187; 22884962; 23102784; 23118302; 23236149; 23283322; 23318115; 23438231; 23485461; 23535823; 23660633; 23704887; 23895422; 24128306 SORT1 Vega:OTTHUMG00000011999 WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding sortilin 1 sortilin 1 SNCA 20140408 4 4q21 6622 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000145335 GO_0000287 (EC: IDA, PMID: 11850416); GO_0001774 (EC: IEA); GO_0001921 (EC: IDA, PMID: 18980610); GO_0001933 (EC: IEA); GO_0001956 (EC: IEA); GO_0005504 (EC: IDA, Qualifier: NOT, PMID: 16687662); GO_0005507 (EC: IDA); GO_0005509 (EC: IDA, PMID: 11312271); GO_0005515 (EC: IPI, PMID: 11943812); GO_0005543 (EC: IEA); GO_0005576 (EC: TAS); GO_0005634 (EC: IDA, PMID: 12406186); GO_0005640 (EC: IEA); GO_0005737 (EC: IDA, PMID: 12406186); GO_0005739 (EC: IEA); GO_0005791 (EC: IEA); GO_0005794 (EC: IEA); GO_0005829 (EC: IDA, PMID: 8248242); GO_0005840 (EC: IEA); GO_0005886 (EC: IDA, PMID: 12958153); GO_0005938 (EC: IDA, PMID: 19157893); GO_0006631 (EC: IEA); GO_0006638 (EC: IEA); GO_0006644 (EC: IEA); GO_0006919 (EC: IDA); GO_0007006 (EC: IEA); GO_0007568 (EC: IEA); GO_0008017 (EC: IEA); GO_0008021 (EC: IEA); GO_0008198 (EC: IDA, PMID: 11850416); GO_0008270 (EC: IDA, PMID: 11850416); GO_0008344 (EC: IEA); GO_0010040 (EC: IDA, PMID: 11850416); GO_0010517 (EC: IDA, PMID: 15641770); GO_0010642 (EC: IDA, PMID: 12239163); GO_0014048 (EC: IEA); GO_0014059 (EC: TAS); GO_0015629 (EC: IDA, PMID: 17408955); GO_0016234 (EC: IDA); GO_0016491 (EC: IDA); GO_0019894 (EC: IPI, PMID: 16176937); GO_0019904 (EC: IEA); GO_0030054 (EC: IEA); GO_0030424 (EC: IDA, PMID: 12958153); GO_0030426 (EC: IDA, PMID: 12958153); GO_0030544 (EC: IPI, PMID: 18975920); GO_0031092 (EC: IDA, Qualifier: colocalizes_with, PMID: 12239163); GO_0031115 (EC: IDA); GO_0031623 (EC: IDA, PMID: 18980610); GO_0031648 (EC: IDA); GO_0032026 (EC: IDA, PMID: 11850416); GO_0032410 (EC: IDA, PMID: 16882008); GO_0032496 (EC: IDA, PMID: 12406186); GO_0032769 (EC: IDA, PMID: 11943812); GO_0033138 (EC: ISS); GO_0034341 (EC: IDA, PMID: 19157893); GO_0034599 (EC: IEA); GO_0035067 (EC: IDA, PMID: 16959795); GO_0040012 (EC: IEA); GO_0042393 (EC: IDA, PMID: 16959795); GO_0042416 (EC: TAS); GO_0042493 (EC: IEA); GO_0042775 (EC: IEA); GO_0042802 (EC: IPI, PMID: 16330551); GO_0043014 (EC: IPI, PMID: 11698390); GO_0043027 (EC: IDA, PMID: 10818098); GO_0043030 (EC: IEA); GO_0043066 (EC: IMP, PMID: 10818098); GO_0043154 (EC: IMP, PMID: 10818098); GO_0043195 (EC: IEA); GO_0043205 (EC: IDA, PMID: 18346205); GO_0043206 (EC: TAS); GO_0043274 (EC: IEA); GO_0043524 (EC: IEA); GO_0044344 (EC: IEA); GO_0045502 (EC: IPI, PMID: 16176937); GO_0045807 (EC: IDA, PMID: 18980610); GO_0045920 (EC: IMP, PMID: 12239163); GO_0045963 (EC: IEA); GO_0047485 (EC: IEA); GO_0048148 (EC: IEA); GO_0048156 (EC: IDA, PMID: 17408955); GO_0048169 (EC: IEA); GO_0048471 (EC: IDA); GO_0048487 (EC: IEA); GO_0048488 (EC: ISS); GO_0050808 (EC: IEA); GO_0050812 (EC: IEA); GO_0051219 (EC: IDA); GO_0051281 (EC: IDA, PMID: 15641770); GO_0051583 (EC: TAS); GO_0051585 (EC: IDA, PMID: 12958153); GO_0051612 (EC: IDA, PMID: 16882008); GO_0051622 (EC: IDA, PMID: 17156375); GO_0055074 (EC: IDA, Qualifier: NOT, PMID: 12239163); GO_0055114 (EC: IDA); GO_0060079 (EC: IEA); GO_0060291 (EC: IEA); GO_0060732 (EC: IDA, PMID: 15641770); GO_0060961 (EC: IDA, Qualifier: NOT, PMID: 19146388); GO_0070495 (EC: IDA, PMID: 12239163); GO_0070555 (EC: IDA, PMID: 12406186); GO_0071280 (EC: IDA); GO_0071872 (EC: TAS); GO_0071902 (EC: IDA) HGNC:11138 HPRD:01227 MIM:163890 NACP Official from a nomenclature committee PARK1 PARK4 PD1 PMID: 7558013; 7568089; 7601450; 7601479; 7802671; 8248242; 8895469; 9163350; 9197268; 9462735; 9750188; 10092675; 10319874; 10407019; 10417297; 10464279; 10506125; 10617630; 10764738; 10818098; 10852916; 10973942; 11078745; 11156617; 11162638; 11173882; 11207390; 11227130; 11261505; 11279280; 11292651; 11312271; 11331421; 11357958; 11376188; 11425308; 11438481; 11447312; 11472875; 11487204; 11502187; 11532993; 11588587; 11603807; 11683992; 11687285; 11698390; 11701929; 11724769; 11742726; 11744621; 11748744; 11751692; 11790792; 11812148; 11812782; 11813001; 11814343; 11814405; 11821392; 11823645; 11850416; 11852183; 11889756; 11893734; 11900526; 11943812; 11956199; 12025860; 12042811; 12044636; 12059041; 12062445; 12070658; 12084935; 12096713; 12115139; 12121974; 12122208; 12124613; 12138709; 12145295; 12151787; 12217698; 12220378; 12239163; 12351642; 12352614; 12358748; 12367530; 12377775; 12406186; 12428717; 12428728; 12477932; 12493604; 12534279; 12534296; 12541013; 12551928; 12558071; 12576551; 12586824; 12598733; 12610000; 12661766; 12670421; 12672538; 12672549; 12684441; 12695511; 12714745; 12716427; 12716914; 12722828; 12727333; 12752402; 12783249; 12784265; 12807436; 12807439; 12815044; 12815663; 12819014; 12857790; 12859192; 12859200; 12867415; 12868067; 12868068; 12885775; 12893833; 12900507; 12923179; 12923682; 12928483; 12958153; 12963044; 12973692; 14506232; 14507911; 14550771; 14572463; 14583385; 14593171; 14596606; 14627698; 14645218; 14657499; 14657500; 14690528; 14692700; 14699135; 14711827; 14742448; 14755719; 14756560; 14987449; 14996933; 14997013; 15028717; 15033366; 15050722; 15064394; 15078109; 15096050; 15099020; 15103328; 15109581; 15132984; 15135042; 15155902; 15159488; 15180968; 15207266; 15234109; 15236975; 15247485; 15265037; 15280438; 15282274; 15289452; 15300629; 15304594; 15317865; 15333840; 15338643; 15364911; 15365127; 15451224; 15451225; 15455394; 15459341; 15465356; 15489334; 15496679; 15498564; 15502868; 15502874; 15522241; 15522881; 15541000; 15542733; 15544803; 15556002; 15576511; 15590652; 15590933; 15591046; 15596612; 15615715; 15615727; 15622440; 15628875; 15628878; 15632170; 15641770; 15670652; 15671022; 15671169; 15671870; 15672325; 15673432; 15684072; 15685368; 15717024; 15718234; 15731118; 15732111; 15755676; 15765523; 15767574; 15791003; 15817478; 15840579; 15845543; 15852347; 15854772; 15863497; 15894486; 15895422; 15896322; 15904919; 15911350; 15917102; 15935068; 15935070; 15939304; 15941712; 15944382; 15955578; 15976091; 15978696; 15981014; 16020543; 16020550; 16037493; 16051265; 16081040; 16096643; 16110277; 16166095; 16176937; 16216085; 16227205; 16239214; 16242637; 16250025; 16269331; 16291942; 16297908; 16330147; 16330551; 16338184; 16344560; 16358335; 16365047; 16399671; 16403519; 16406146; 16410343; 16455667; 16464864; 16500997; 16516382; 16520971; 16524375; 16543523; 16567160; 16595633; 16604306; 16606366; 16606927; 16609851; 16611810; 16618118; 16651889; 16678164; 16679556; 16679557; 16687662; 16714300; 16752390; 16762368; 16780837; 16794039; 16806952; 16824047; 16847063; 16882008; 16896109; 16896314; 16930553; 16934409; 16947080; 16953580; 16959772; 16959793; 16959795; 16981712; 16997873; 17005870; 17010992; 17012252; 17012257; 17017516; 17017543; 17049244; 17055279; 17077307; 17078049; 17156375; 17156376; 17166628; 17174013; 17176082; 17199224; 17200685; 17209557; 17209570; 17222106; 17254569; 17291816; 17292657; 17309880; 17325715; 17335904; 17373725; 17374032; 17374033; 17374364; 17376994; 17387688; 17408955; 17451452; 17465029; 17489854; 17530780; 17531291; 17531952; 17554782; 17558898; 17573347; 17576801; 17603039; 17625105; 17635667; 17653558; 17675576; 17681534; 17683088; 17692832; 17706644; 17708336; 17712623; 17714183; 17785456; 17853477; 17868672; 17872362; 17873367; 17893145; 17904099; 17918232; 17955272; 17963364; 17982729; 17985233; 18000672; 18005258; 18018485; 18018486; 18031063; 18036154; 18039462; 18055555; 18061619; 18065497; 18070888; 18162487; 18162536; 18178617; 18179253; 18182484; 18182779; 18195004; 18195271; 18210157; 18211709; 18221373; 18245082; 18258594; 18261456; 18261982; 18282005; 18291704; 18295208; 18314273; 18322262; 18322396; 18322646; 18329380; 18331289; 18335262; 18343814; 18346205; 18362284; 18369446; 18382667; 18390556; 18393229; 18404644; 18413475; 18417705; 18423664; 18436529; 18436957; 18440504; 18449945; 18451726; 18463503; 18463504; 18485051; 18491043; 18492487; 18494470; 18505736; 18539297; 18541113; 18541383; 18562315; 18566453; 18568448; 18571778; 18606870; 18614564; 18617532; 18622040; 18625222; 18634833; 18650345; 18661559; 18676060; 18692132; 18702517; 18702696; 18704197; 18704525; 18708765; 18751989; 18769546; 18775438; 18824390; 18843496; 18848547; 18852445; 18852892; 18951507; 18955133; 18973254; 18973346; 18975920; 18980610; 18985386; 19002552; 19004816; 19018246; 19022350; 19027885; 19032594; 19047559; 19049426; 19070597; 19071095; 19074459; 19101068; 19115126; 19126542; 19135032; 19139307; 19141614; 19146388; 19151622; 19152986; 19157893; 19164293; 19167501; 19182805; 19183551; 19196539; 19198857; 19203374; 19205068; 19219857; 19220042; 19224617; 19224863; 19248830; 19261853; 19289119; 19291219; 19295143; 19328209; 19345692; 19356597; 19361478; 19369384; 19404653; 19405094; 19410557; 19412953; 19429025; 19444607; 19460374; 19460457; 19470380; 19475667; 19476547; 19498036; 19501571; 19507712; 19526103; 19526281; 19535993; 19540308; 19548659; 19549071; 19553474; 19562770; 19576176; 19576220; 19580781; 19596443; 19609719; 19630439; 19632874; 19645749; 19646423; 19651612; 19651786; 19653131; 19655784; 19680561; 19722699; 19747490; 19759002; 19762560; 19771175; 19816809; 19826908; 19833127; 19833540; 19834617; 19837084; 19845160; 19847913; 19855133; 19875982; 19878656; 19889641; 19890971; 19891973; 19892735; 19895818; 19900407; 19915575; 19915576; 20026050; 20029978; 20036828; 20041693; 20043104; 20070850; 20071342; 20074453; 20074637; 20077428; 20089532; 20098416; 20106983; 20114052; 20121219; 20132485; 20140223; 20148295; 20152114; 20169066; 20197038; 20226185; 20301402; 20334438; 20334701; 20371330; 20379614; 20381070; 20383623; 20392839; 20403393; 20409326; 20423081; 20423294; 20437598; 20445049; 20445061; 20448034; 20463956; 20478361; 20489724; 20506312; 20513365; 20524960; 20533263; 20534649; 20540950; 20540987; 20550572; 20554859; 20599975; 20604806; 20615443; 20629174; 20634198; 20640532; 20648655; 20664293; 20664530; 20668263; 20669025; 20685363; 20693280; 20696318; 20697047; 20697102; 20711177; 20725866; 20798282; 20805224; 20828147; 20842103; 20847452; 20849899; 20854101; 20855506; 20876215; 20876472; 20887775; 20887871; 20919750; 20945981; 20947801; 20959456; 20969957; 20977677; 21044603; 21044948; 21046180; 21054681; 21056999; 21058943; 21060011; 21084426; 21085664; 21103359; 21103907; 21108951; 21116546; 21117662; 21124796; 21127069; 21159074; 21162130; 21166675; 21167933; 21179192; 21212878; 21215793; 21235576; 21236518; 21238487; 21245015; 21245577; 21248740; 21249223; 21255620; 21256122; 21271299; 21272100; 21280130; 21289072; 21292315; 21296890; 21300904; 21304957; 21309955; 21310263; 21317042; 21319811; 21330368; 21330369; 21331461; 21338582; 21342025; 21358815; 21391235; 21412942; 21425343; 21439320; 21443877; 21445308; 21453448; 21461961; 21462277; 21466165; 21474915; 21488084; 21489994; 21491910; 21524999; 21527634; 21541339; 21565333; 21570984; 21593311; 21600984; 21601954; 21611169; 21613474; 21641618; 21652707; 21653695; 21656370; 21656851; 21658409; 21658411; 21672073; 21683963; 21684335; 21689664; 21693148; 21693152; 21699177; 21700325; 21714002; 21718702; 21720016; 21721555; 21736378; 21738487; 21742527; 21746851; 21756873; 21757905; 21767644; 21779395; 21782946; 21795682; 21798243; 21798244; 21813214; 21816655; 21819966; 21832049; 21832061; 21838671; 21841800; 21846727; 21848810; 21849493; 21853288; 21858077; 21863007; 21865317; 21880335; 21883224; 21900206; 21905118; 21936000; 21953452; 21953697; 21953863; 21985244; 21990355; 21993592; 21994367; 22001247; 22003392; 22009045; 22009151; 22025277; 22029383; 22039514; 22042430; 22045699; 22065755; 22067166; 22076805; 22079575; 22082318; 22090514; 22104010; 22119730; 22147697; 22153624; 22155643; 22163275; 22165993; 22166424; 22167382; 22178859; 22182688; 22207004; 22227187; 22243833; 22248692; 22262231; 22267729; 22275250; 22286107; 22291217; 22302797; 22314685; 22315227; 22315428; 22319455; 22326202; 22334684; 22349157; 22350713; 22357653; 22361813; 22367999; 22392151; 22399752; 22399753; 22407793; 22411133; 22425546; 22426402; 22436655; 22438815; 22445250; 22451204; 22453917; 22475625; 22503729; 22508282; 22508489; 22513881; 22533435; 22537068; 22549133; 22550057; 22552968; 22558453; 22560502; 22570709; 22573613; 22581044; 22591216; 22610785; 22615757; 22617348; 22619171; 22622968; 22647715; 22669510; 22694188; 22695112; 22701661; 22705949; 22735540; 22737239; 22764233; 22767608; 22771474; 22771809; 22776201; 22814000; 22819391; 22821666; 22836259; 22843682; 22850485; 22860160; 22863883; 22880029; 22912757; 22914317; 22923346; 22923347; 22923367; 22936307; 22939629; 22940885; 22941029; 22944910; 22948283; 22961477; 22981881; 22983916; 22986484; 22988096; 23000061; 23011138; 23013868; 23022913; 23028833; 23038403; 23039195; 23077033; 23077527; 23098910; 23100443; 23123341; 23129765; 23149132; 23153578; 23175842; 23180276; 23182315; 23183827; 23200460; 23201181; 23225002; 23225009; 23225525; 23244416; 23250862; 23252394; 23283657; 23284971; 23300640; 23300799; 23308173; 23313024; 23319586; 23328951; 23333298; 23334595; 23344955; 23349712; 23360753; 23361255; 23362176; 23365056; 23374072; 23374074; 23383169; 23384371; 23389286; 23392688; 23413261; 23426727; 23437071; 23452040; 23454347; 23454680; 23457458; 23458258; 23463005; 23466394; 23492776; 23499431; 23505409; 23507417; 23509976; 23509978; 23532841; 23534813; 23553480; 23562552; 23576548; 23580063; 23583776; 23587141; 23603399; 23603979; 23607785; 23609437; 23626796; 23630590; 23656991; 23661100; 23667637; 23669636; 23674386; 23674458; 23674490; 23703938; 23705016; 23737253; 23739956; 23744071; 23744550; 23796501; 23817832; 23820587; 23827677; 23831067; 23891486; 23900411; 23936403; 24005725; 24026176; 24047453; 24066883; 24070323; 24113654; 24191706; 24218576; 24315858; 24374342; 24381286; 24501346 SNCA WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding synuclein, alpha (non A4 component of amyloid precursor) synuclein, alpha (non A4 component of amyloid precursor) SORL1 11 11q23.2-q24.2 20140408 6653 9606 Bin Zhao, Yue Liu, Oliver He C11orf32 Ensembl:ENSG00000137642 GO_0004888 (EC: TAS, PMID: 9157966); GO_0005515 (EC: IPI, PMID: 14764453); GO_0005615 (EC: IDA, PMID: 14764453); GO_0005768 (EC: IDA, PMID: 16174740); GO_0005771 (EC: IEA); GO_0005794 (EC: IDA, PMID: 16174740); GO_0005887 (EC: TAS, PMID: 9157966); GO_0006605 (EC: IMP, PMID: 16174740); GO_0006869 (EC: IEA); GO_0006898 (EC: TAS, PMID: 9157966); GO_0007165 (EC: TAS, PMID: 9157966); GO_0008203 (EC: IEA); GO_0008219 (EC: IEA); GO_0008283 (EC: IEA); GO_0014910 (EC: IDA, PMID: 14764453); GO_0016020 (EC: IDA, PMID: 14764453); GO_0016477 (EC: IEA); GO_0030169 (EC: IPI, PMID: 17326667); GO_0034362 (EC: IEA); GO_0043025 (EC: IEA); GO_0070062 (EC: IDA, PMID: 19056867) HGNC:11185 HPRD:03595 LR11 LRP9 MIM:602005 Official from a nomenclature committee PMID: 8619474; 8940146; 9157966; 10375696; 11294867; 11557679; 11821067; 12477932; 12530537; 12970790; 14702039; 14764453; 15313836; 16174740; 16344560; 16407538; 16489755; 16531402; 16565469; 17110338; 17220890; 17326667; 17420311; 17589324; 17721864; 17826910; 17949987; 17975299; 17978276; 18063222; 18090307; 18093545; 18407551; 18541377; 18562096; 18603531; 18685254; 18713574; 18830724; 18938222; 19056867; 19064752; 19077115; 19364927; 19368828; 19539718; 19584446; 19653016; 19822782; 19889229; 19889475; 19913121; 20015111; 20047743; 20301340; 20379614; 20413850; 20534741; 20574532; 20625269; 20628086; 20634593; 20667857; 20689279; 20838585; 20880607; 20946940; 20970138; 21145461; 21147781; 21185108; 21206043; 21220680; 21385844; 21730226; 21989385; 21994944; 21997402; 22044026; 22127416; 22268729; 22279231; 22286501; 22297619; 22321011; 22472873; 22621900; 22750733; 22836009; 22927900; 22996644; 23127357; 23455993; 23463934; 23486467; 23525328; 23565137; 23602568; 23813966; 24001769 SORL1 SORLA SorLA-1 Vega:OTTHUMG00000166057 WEB: http://www.ncbi.nlm.nih.gov/gene gp250 protein-coding sortilin-related receptor, L(DLR class) A repeats containing sortilin-related receptor, L(DLR class) A repeats containing HNF1A 12 12q24.2 20140408 6927 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000135100 GO_0001077 (EC: ISS); GO_0003677 (EC: IDA, PMID: 10333057); GO_0003700 (EC: IDA, PMID: 11980910); GO_0005515 (EC: IPI, PMID: 11980910); GO_0005634 (EC: IDA); GO_0005730 (EC: IDA, Qualifier: NOT); GO_0005737 (EC: IDA, PMID: 12530534); GO_0006357 (EC: IDA, PMID: 10330009); GO_0030073 (EC: IMP, PMID: 10333057); GO_0035565 (EC: IMP, Qualifier: NOT, PMID: 15355349); GO_0035623 (EC: IMP, PMID: 11269503); GO_0042593 (EC: IMP, PMID: 11269503); GO_0042803 (EC: IPI, PMID: 1677179); GO_0043234 (EC: IDA, PMID: 11980910); GO_0043565 (EC: IEA); GO_0044212 (EC: IDA, PMID: 12453420); GO_0045893 (EC: IDA, PMID: 11980910); GO_0045944 (EC: ISS); GO_0046323 (EC: IMP, PMID: 11269503); GO_0046982 (EC: IDA, PMID: 12530534); GO_0046983 (EC: IPI, PMID: 12453420); GO_0060261 (EC: IGI, PMID: 15355349) HGNC:11621 HNF-1A HNF1 HNF1 homeobox A HNF1 homeobox A HNF1A HPRD:00800 IDDM20 LFB1 MIM:142410 MODY3 Official from a nomenclature committee PMID: 1535333; 1677179; 1707031; 2044952; 2263635; 2460858; 7795649; 7900999; 8288579; 8945470; 9032114; 9075818; 9075819; 9092652; 9097962; 9112026; 9133564; 9166684; 9287053; 9287055; 9313763; 9313764; 9392505; 9439666; 9604876; 9621514; 9626139; 9754819; 9792724; 9867222; 10078571; 10084598; 10102714; 10209158; 10330009; 10333057; 10482964; 10588527; 10649494; 10677375; 10777539; 10779377; 10944108; 11134330; 11162430; 11266540; 11269503; 11440371; 11522670; 11668618; 11772903; 11827432; 11938027; 11978637; 11980910; 12011060; 12012276; 12050210; 12107263; 12107757; 12235114; 12355088; 12378390; 12442280; 12453420; 12453961; 12453975; 12453976; 12477932; 12488960; 12488961; 12488962; 12530534; 12544512; 12547858; 12565907; 12574234; 12605834; 12627330; 12707037; 12712243; 12726923; 12730871; 12743700; 12762846; 12773136; 12788852; 12794133; 12860991; 12934344; 14500717; 14575719; 14583183; 14715527; 14728801; 14747304; 14988562; 15111528; 15194767; 15217781; 15270800; 15277395; 15300627; 15305805; 15326484; 15355349; 15489334; 15520459; 15522234; 15542842; 15569134; 15598887; 15616580; 15660195; 15660729; 15740590; 15830177; 15841481; 15847654; 15899904; 15928245; 15930087; 15961790; 15983230; 15983330; 16046299; 16046319; 16147992; 16186275; 16223942; 16241915; 16249556; 16254374; 16276364; 16297991; 16341674; 16367885; 16442529; 16443774; 16562587; 16632067; 16675441; 16712787; 16714285; 16752173; 16760222; 16781669; 16788384; 16793932; 16873704; 16893891; 16930618; 16963153; 17021248; 17033837; 17037983; 17049664; 17116178; 17130528; 17192490; 17194452; 17264800; 17327436; 17353931; 17407072; 17440016; 17440429; 17458140; 17475670; 17569132; 17573900; 17601994; 17638895; 17828387; 17932728; 17937063; 17965524; 18003757; 18080173; 18160415; 18172616; 18221440; 18332101; 18346225; 18391435; 18399756; 18433021; 18433912; 18439548; 18439552; 18440731; 18498634; 18513302; 18513305; 18586913; 18593771; 18671716; 18672310; 18720549; 18777455; 18811724; 18854284; 18940312; 19060906; 19119252; 19150152; 19169489; 19188435; 19198612; 19228875; 19264593; 19280766; 19289501; 19304666; 19336507; 19349540; 19351817; 19357985; 19388975; 19453261; 19490620; 19536331; 19564454; 19567438; 19578796; 19672314; 19687008; 19741195; 19749792; 19782160; 19794065; 19878569; 19913121; 19924231; 19933992; 20018894; 20028982; 20031592; 20069546; 20075150; 20096102; 20106981; 20113359; 20132997; 20133952; 20172480; 20195357; 20393147; 20394740; 20396999; 20416077; 20460578; 20546258; 20568120; 20571754; 20581827; 20628086; 20633866; 20634891; 20648472; 20679960; 20682687; 20686565; 20690076; 20705777; 20716378; 20727736; 20738937; 20829431; 20834067; 20863361; 20971364; 20980261; 21047120; 21062467; 21168233; 21170474; 21176092; 21182953; 21195701; 21196492; 21203500; 21208426; 21224407; 21300955; 21348892; 21353246; 21429061; 21437455; 21454713; 21498636; 21573907; 21647738; 21683639; 21747169; 21814873; 21909109; 21975049; 21988832; 22001757; 22010049; 22060211; 22160269; 22290433; 22340386; 22341299; 22357705; 22383952; 22395466; 22413961; 22432108; 22466651; 22474109; 22517943; 22569176; 22665711; 22671145; 22788528; 22798294; 22802087; 22849862; 22939635; 22993150; 23009393; 23052196; 23144326; 23183503; 23263486; 23274891; 23348805; 23430038; 23603156; 23607861; 23616187; 23679181; 23760703; 23803251; 23824729; 23844046; 23878349; 23922447; 24100303 TCF-1 TCF1 Vega:OTTHUMG00000151015 WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding TBK1 12 12q14.1 20140408 29110 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000183735 GO_0002224 (EC: TAS); GO_0002756 (EC: TAS); GO_0003676 (EC: IEA); GO_0004672 (EC: NAS, PMID: 10581243); GO_0004674 (EC: TAS); GO_0005515 (EC: IPI, PMID: 14743216); GO_0005524 (EC: IEA); GO_0005737 (EC: IDA); GO_0005829 (EC: TAS); GO_0006954 (EC: TAS); GO_0007249 (EC: TAS); GO_0009615 (EC: TAS); GO_0010008 (EC: TAS); GO_0010629 (EC: IEA); GO_0016032 (EC: IEA); GO_0032480 (EC: TAS); GO_0032481 (EC: TAS); GO_0032606 (EC: TAS); GO_0032727 (EC: IDA, PMID: 16127453); GO_0032728 (EC: IDA, PMID: 16127453); GO_0033138 (EC: NAS); GO_0034138 (EC: TAS); GO_0034142 (EC: TAS); GO_0035666 (EC: TAS); GO_0043123 (EC: IEP, PMID: 12761501); GO_0045087 (EC: TAS); GO_0045359 (EC: IEA); GO_0045944 (EC: IDA, PMID: 16127453); GO_0050830 (EC: IEA); GO_0051219 (EC: IPI, PMID: 14530355); GO_0051607 (EC: IEA) HGNC:11584 HPRD:05322 MIM:604834 NAK Official from a nomenclature committee PMID: 7706279; 8601309; 9721103; 10581243; 10783893; 10990461; 11839743; 12133833; 12477932; 12568715; 12692549; 12702806; 12761501; 14530355; 14560022; 14702039; 14743216; 15276183; 15367631; 15485837; 15489227; 15489334; 15556946; 15619605; 15661910; 15695821; 15841462; 16051665; 16127453; 16153868; 16155125; 16223731; 16281057; 16344560; 16380379; 16393995; 16394098; 16537515; 16887178; 16888014; 16914100; 16973572; 17018283; 17327220; 17526488; 17568778; 17599067; 17823124; 17991829; 18307994; 18353649; 18508731; 18583960; 18614628; 18636086; 18977754; 19017982; 19153231; 19160540; 19307177; 19380831; 19419966; 19615732; 19656901; 19820708; 19847166; 19953087; 19955181; 19958770; 20098747; 20174559; 20304918; 20331378; 20449947; 20462248; 20562859; 20588308; 20628368; 21048031; 21074459; 21139048; 21204785; 21270402; 21332394; 21364999; 21447600; 21464307; 21492457; 21617041; 21813773; 21832049; 21868362; 21885437; 21903422; 21906983; 21911421; 21931631; 21939555; 21963094; 21987572; 21988832; 22072751; 22079989; 22127978; 22261722; 22306015; 22330071; 22388039; 22394562; 22505724; 22610919; 22619329; 22745133; 22787218; 22792062; 22851595; 22851696; 22908223; 22939624; 22945920; 23007157; 23028469; 23096996; 23157677; 23209807; 23286385; 23308279; 23395611; 23395801; 23453972; 23542348; 23649622; 23675467; 23717208; 23836654; 23950712; 23962979; 24027431; 24056301; 24062311; 24250222; 24255178; 24449872 T2K TANK-binding kinase 1 TANK-binding kinase 1 TBK1 Vega:OTTHUMG00000168796 WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding TREM2 20140408 54209 6 6p21.1 9606 Bin Zhao, Yue Liu, Oliver He Ensembl:ENSG00000095970 GO_0001530 (EC: IEA); GO_0004872 (EC: TAS, PMID: 10799849); GO_0005576 (EC: IEA); GO_0005886 (EC: TAS); GO_0006959 (EC: TAS, PMID: 10799849); GO_0007411 (EC: TAS); GO_0016021 (EC: IEA); GO_0045087 (EC: TAS) HGNC:17761 HPRD:05473 MIM:605086 Official from a nomenclature committee PMID: 10799849; 12080485; 12477932; 12645956; 12754369; 12913093; 12925681; 15489334; 15966270; 16505336; 16715077; 17530208; 18546367; 18551625; 19019460; 19079182; 19230638; 19457124; 19913121; 20301376; 20421649; 20628086; 20640189; 21834902; 22939635; 23150908; 23150934; 23380991; 23391427; 23407992; 23533697; 23582655; 23721075; 23759145; 23800361; 23855982; 23855984; 23870839; 24078628; 24131187 RP1-238O23.2 TREM-2 TREM2 Trem2a Trem2b Trem2c Vega:OTTHUMG00000014671 WEB: http://www.ncbi.nlm.nih.gov/gene protein-coding triggering receptor expressed on myeloid cells 2 triggering receptor expressed on myeloid cells 2 LRRK2 12 120892 12q12 20140408 9606 AURA17 Bin Zhao, Yue Liu, Oliver He DARDARIN Ensembl:ENSG00000188906 GO_0000165 (EC: IDA, PMID: 17200152); GO_0000186 (EC: IDA, PMID: 19302196); GO_0000187 (EC: IDA, PMID: 19302196); GO_0001934 (EC: IMP); GO_0003924 (EC: IDA); GO_0004672 (EC: IDA, PMID: 16269541); GO_0004674 (EC: IDA, PMID: 17200152); GO_0004708 (EC: IDA, PMID: 19302196); GO_0005096 (EC: IDA, PMID: 17442267); GO_0005515 (EC: IPI, PMID: 16321986); GO_0005524 (EC: IEA); GO_0005525 (EC: IDA, PMID: 16980962); GO_0005615 (EC: IDA); GO_0005737 (EC: IDA, PMID: 16321986); GO_0005739 (EC: IDA); GO_0005802 (EC: IEA); GO_0005829 (EC: IDA); GO_0005886 (EC: IEA); GO_0006184 (EC: IDA); GO_0006914 (EC: IEA); GO_0006979 (EC: IMP, PMID: 19692353); GO_0007264 (EC: IEA); GO_0007528 (EC: IMP); GO_0008021 (EC: IEA); GO_0008340 (EC: IMP, PMID: 19692353); GO_0010508 (EC: IMP); GO_0010508 (EC: ISS); GO_0014041 (EC: IMP); GO_0015631 (EC: IDA); GO_0016234 (EC: IMP); GO_0017048 (EC: IPI); GO_0018105 (EC: IDA, PMID: 19576176); GO_0018107 (EC: IDA); GO_0021772 (EC: IMP); GO_0022028 (EC: IMP); GO_0030424 (EC: IEA); GO_0031398 (EC: IDA, PMID: 16352719); GO_0031966 (EC: IDA); GO_0032436 (EC: ISS); GO_0032473 (EC: IDA, PMID: 16269541); GO_0032839 (EC: IDA); GO_0034211 (EC: IDA, PMID: 17260967); GO_0034211 (EC: IMP, PMID: 17200152); GO_0034260 (EC: IDA); GO_0035564 (EC: ISS); GO_0035640 (EC: IMP); GO_0040012 (EC: IMP, PMID: 19692353); GO_0042391 (EC: IMP); GO_0042802 (EC: IPI, PMID: 16321986); GO_0042803 (EC: IPI, PMID: 16321986); GO_0043005 (EC: IDA); GO_0043025 (EC: IDA); GO_0043068 (EC: IDA, PMID: 17200152); GO_0043547 (EC: IDA, PMID: 17442267); GO_0044325 (EC: IPI); GO_0045121 (EC: IEA); GO_0046777 (EC: IDA, PMID: 16269541); GO_0046777 (EC: IMP, PMID: 16980962); GO_0048312 (EC: IMP); GO_0051018 (EC: IPI); GO_0060161 (EC: IMP); GO_0061001 (EC: IMP); GO_0070062 (EC: IDA, PMID: 19056867); GO_0070997 (EC: IMP, PMID: 19692353); GO_0071407 (EC: IEA); GO_1902692 (EC: IMP); GO_2000172 (EC: IMP) HGNC:18618 LRRK2 MIM:609007 Official from a nomenclature committee PARK8 PMID: 11891824; 12213963; 12477932; 14691730; 14702039; 15146197; 15541308; 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23241745; 23250886; 23251661; 23268655; 23300640; 23318930; 23325906; 23379419; 23389884; 23421816; 23455607; 23472874; 23507417; 23531835; 23588498; 23628791; 23664753; 23771111; 23820587; 23824357; 23842774; 23916833; 23924436; 23937259; 24015287; 24018986; 24211199; 24326068; 24351927; 24403142 RIPK7 ROCO2 Vega:OTTHUMG00000059742 WEB: http://www.ncbi.nlm.nih.gov/gene leucine-rich repeat kinase 2 leucine-rich repeat kinase 2 protein-coding biological sex sex biological sex sex 生物性 生物性别 An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved. EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000695 James Malone Jie Zheng MO_680 NCIt:C28421 PATO:0000047 Term applied to any organism able to undergo sexual reproduction in order to differentiate the individuals or types involved. Sexual reproduction is defined as the ability to exchange genetic material with the potential of recombinant progeny. The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. Tomasz Adamusiak biological sex biological sex http://mged.sourceforge.net/ontologies/MGEDOntology.owl#sex An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved. EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000695 James Malone Jie Zheng MO_680 NCIt:C28421 PATO:0000047 Term applied to any organism able to undergo sexual reproduction in order to differentiate the individuals or types involved. Sexual reproduction is defined as the ability to exchange genetic material with the potential of recombinant progeny. The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. Tomasz Adamusiak biological sex biological sex http://mged.sourceforge.net/ontologies/MGEDOntology.owl#sex 凭借持有者进行有性增殖的能力，有机体的质量成为持有者的固有部分，由此区分所涉及的个人或类型。 生物性 生物性 男性与女性区别的物理属性或特质的集合;男女之间的生理差异;男性或女性的显著特点。 适用于任何能够进行有性繁殖的生物，以区分所涉及的个体或类型。 female female 女性 A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes. CARO:0000028 James Malone Jie Zheng MO_506 PATO:0000383 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#female A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes. CARO:0000028 James Malone Jie Zheng MO_506 PATO:0000383 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#female 在个体或种群中固有的一种生物性别特性，它只产生可以由雄性配子受精的配子。 male male 雄性 A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes. CARO:0000027 James Malone Jie Zheng MO_652 PATO:0000384 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#male A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes. CARO:0000027 James Malone Jie Zheng MO_652 PATO:0000384 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#male 在个体或群体中固有的生物性质量，即生殖器官只包含雄性配子 physical object quality physical object quality 物理对象性质 physical object quality physical object quality 物理对象性质 cellular quality cellular quality 细胞性质 cellular potency cellular potency 细胞潜能 cellular potency cellular potency 细胞潜能 multipotent multipotent 多能的 multipotent multipotent 多能的 pluripotent pluripotent organismal quality organismal quality 生物性质 organismal quality organismal quality 生物性质 protein protein 蛋白质 An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA. An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA. PR:000000001 Proteins descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. protein 通过一个遗传编码mRNA的核糖体介导的翻译而从头产生的氨基酸链。 CD34 molecule CD34 molecule CD34 分子 A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. CD34 hematopoietic progenitor cell antigen CD34 A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. CD34 hematopoietic progenitor cell antigen CD34 是人CD34基因或其1:1直系同源物的翻译产物的蛋白质。它是由淋巴造血祖细胞特异性表达的白细胞膜蛋白。它包含一个单次跨膜结构域，并在早期造血前体和血管相关组织上显示出不同的表达。作为一个支架，它以成簇、组织特异性的方式呈现出选择素碳水化合物配体，以允许在炎症过程中白细胞和内皮细胞之间更高的亲合力相互作用。与相关的唾液黏蛋白（内切多糖和足细胞标记蛋白）一样，细胞外区域主要是由可被唾液酸化的O-连接碳水化合物密集取代的N-末端粘蛋白样结构域组成。粘蛋白样区域之后是一个含有半胱氨酸的球状结构域。该结构域可以折叠成免疫球蛋白样结构，因为2个半胱氨酸的位置在免疫球蛋白超家族的C2集中是保守的。细胞质结构域长约73-76个残基且高度保守。 造血祖细胞抗原CD34 receptor-type tyrosine-protein phosphatase C receptor-type tyrosine-protein phosphatase C 受体型酪氨酸蛋白磷酸酶C A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. CD45 L-CA PTPRC T200 leukocyte common antigen ly-5 lymphocyte antigen 5 A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. CD45 L-CA PTPRC T200 leukocyte common antigen ly-5 lymphocyte antigen 5 是人PTPRC基因或其1：1直系同源物的翻译产物的蛋白质。它由一个胞外结构域，一个单跨膜片段和两个串联的胞质内蛋白酪氨酸磷酸酶结构域组成。含有1至3个纤连蛋白III型结构域（Pfam：PF00041）的拷贝，随后是两个蛋白酪氨酸磷酸酶（Pfam：PF00102）结构域的拷贝。受体型酪氨酸蛋白磷酸酶C（CD45）通过与T和B细胞上的受体分子特异性结合来调节信号转导和淋巴细胞活化。CD45 (180-235 kDa)的多种亚型可由3个变量外显子4(a)、5(B)和6(C)的选择性剪接产生，编码位于分子的N端胞外区域的序列。 淋巴细胞抗原5 白细胞常见抗原 endoglin endoglin 内皮糖蛋白 A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof. CD105 END ENG Edg cell surface MJ7/18 antigen A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof. CD105 END ENG Edg cell surface MJ7/18 antigen 是人ENG基因或其1：1直系同源物的翻译产物的蛋白质。 细胞表面MJ7/18抗原 5'-nucleotidase 5'-nucleotidase 5'-核苷酸酶 5'-NT A protein that is a translation product of the human NT5E gene or a 1:1 ortholog thereof. CD73 NT5 NT5E NTE ecto-5'-nucleotidase 5'-NT A protein that is a translation product of the human NT5E gene or a 1:1 ortholog thereof. CD73 NT5 NT5E NTE ecto-5'-nucleotidase 是人NT5E基因或其1:1直系同源物的翻译产物的蛋白质。 胞外5'核苷酸酶 Thy-1 membrane glycoprotein Thy-1 membrane glycoprotein Thy-1膜糖蛋白 A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. CD90 CDw90 THY1 Thy-1 Thy-1 antigen A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. CD90 CDw90 THY1 Thy-1 Thy-1 antigen Thy-1抗原 是人THY1基因或其1:1直系同源物的翻译产物的蛋白质。 insulin An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. Category=gene. INS PR:000009054 protein amino acid chain amino acid chain 氨基酸链 An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues linked by peptide bonds or derivatives of such bonds. peptide polypeptide An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues linked by peptide bonds or derivatives of such bonds. An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. Category=external. PR:000018263 peptide polypeptide protein 多肽 是氨基酸链成分的聚合物的有机氨基化合物（未修饰的氨基酸残基和/或通过肽键或这些键的衍生物连接修饰的氨基酸残基）。 肽 modified amino-acid residue An organic group that results from covalent modification or chemical alteration to the side chain or backbone atoms of an amino acid residue or derivative thereof, where such alteration maintains the integrity of the amino acid chain containing the residue. Category=external. Note: This entity is distinct from MOD:00000 "protein modification" in that the latter includes proteolytic cleavages. [PRO:DAN, PRO:JSG] PR:000025513 modified amino acid chain residue modified protein residue protein unmodified amino-acid residue An amino-acid residue that has not been covalently modified by chemical alteration to the side chain or backbone atoms. Category=external. PR:000026291 protein unmodified amino acid chain residue unmodified protein residue peptidyl modified amino-acid residue An amino-acid residue that results from covalent modification or chemical alteration to the side chain or backbone atoms such that the peptide bonds remain. Category=external. PR:000036198 protein non-peptidyl modified amino-acid residue An organic group that results from covalent modification or chemical alteration to the backbone atoms of amino acid residues so that their peptide bond is altered but the C1 and alpha-N bond is uncleaved. Category=external. PR:000036199 protein amino acid chain component 氨基酸链组分 A fiat object part that is either a modified amino-acid residue or an unmodified amino-acid residue. Category=external. Note: This entity is distinct from CHEBI: "amino-acid residue" in that it includes residues that are technically not part of that class. [PRO:JSG] PR:000036907 amino-acid residue protein 氨基酸残基 类别=外部。 注意：该实体不同于CHEBI：“氨基酸残基”，因为它包括技术上不属于该类别的残基。[PRO：JSG] 虚拟对象部分，它是一个修饰的氨基酸残基或一个未修饰的氨基酸残基。 蛋白 insulin family protein A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. Category=family. PR:000045358 fam:INS protein peripheral nervous system A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. PNS pars peripherica systema nervosum periphericum zone of skin zone of skin 皮肤区 (...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG] Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. EHDAA2:0001844 EHDAA2:0001844 EHDAA:6530 EHDAA:6530 EMAPA:17525 EMAPA:17525 EV:0100152 EV:0100152 FMA:86166 FMA:86166 GAID:933 GAID:933 MA:0000151 MA:0000151 MAT:0000284 MAT:0000284 MESH:D012867 MESH:D012867 MIAA:0000284 MIAA:0000284 Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA UBERON:0000014 UBERON:0000014 VHOG:0000860 VHOG:0000860 portion of skin portion of skin region of skin region of skin skin skin skin region skin region skin zone skin zone uberon uberon we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive (...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG] Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. EHDAA2:0001844 EHDAA:6530 EMAPA:17525 EV:0100152 FMA:86166 GAID:933 MA:0000151 MAT:0000284 MESH:D012867 MIAA:0000284 Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA UBERON:0000014 VHOG:0000860 portion of skin region of skin skin skin region skin zone uberon we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive 我们假设他们说皮肤时小鼠、HOG和GAID都指皮肤区域。因此，我们选择皮肤作为一个确切的同义词，因为它更直观 皮肤 皮肤区域(region of skin) 皮肤区域(skin region) 皮肤区域(skin zone) 覆盖身体的器官的任何部分，由一层表皮和一层真皮组成。 请注意身体的整个皮肤（生物体中只有1个）和皮肤区域（皮肤区域可能有很多）之间的区别。 例如：膝盖的皮肤 部分皮肤 （...）这是已为大家接受的，即神经嵴细胞促进两个真皮骨架（硬骨鱼的骨颅面、牙齿和尾鳍鳍条）和外皮，包括颅面真皮和视网膜外的所有色素细胞（...）[well established] [VHOG] cutaneous appendage Anatomical projection that protrudes from the skin. Examples: hair, nail, feather, claw, hoof, horn, wattle, spur, beak, antler, bristle and some scales. CALOHA:TS-0051 CALOHA:TS-0051 FMA:71012 FMA:71012 Mammary glands develop by similar mechanisms, and there is an argument for including them here (e.g. http://www.ncbi.nlm.nih.gov/pubmed/20484386), but these structures do not fit the current definition (lactiferous glands are part of the integumentary system in FMA). Note the FMA class is a subdivision of epidermis, which may be too restrictive for our purposes here. UBERON:0000021 UBERON:0000021 epidermal appendage epidermal appendage epidermal growth epidermal growth skin appendage skin appendage uberon uberon tube tube 管 Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. UBERON:0000025 anatomical tube anatomical tube duct duct galen:Tube not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts) tubular uberon Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. UBERON:0000025 anatomical tube anatomical tube duct duct galen:Tube not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts) tubular uberon 不是每个解剖学导管都是一根管 - 例如，骨孔是骨头的开口，并且没有明显的单独的管结构。 管子可以运送大的混合物（例如消化管中的食物团）或者可以运输单个腺的分泌物（例如腺管） 任何中空的圆柱形解剖结构，包含一个运输物质的管腔。 管道 管道 肾小管 解剖管 解剖管 appendage AEO:0000193 An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA][BILA:0000018]. BILA:0000018 BTO:0001492 CARO:0010003 EFO:0000799 EHDAA2:0003193 EV:0100155 FBbt:00007000 HAO:0000144 MAT:0000023 MESH:D005121 MIAA:0000023 Major subdivision of an organism that protrudes from the body[DOS, CARO]. OpenCyc:Mx4rvViC-JwpEbGdrcN5Y29ycA Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified][GO:0048736]. UBERON:0000026 UMLS:C0598782 VSAO:0000075 XAO:0000218 appendages appendicular extremitaet extremity limbs/digits/tail this is currently a subtype of organism subdivision - which would exclude feathers uberon head head 头部 The head is the anterior-most division of the body [GO]. adult head cephalic area head (volume) The head is the anterior-most division of the body [GO]. adult head cephalic area head (volume) 头部区域 头部是身体最前面的部分[GO]。 头（体积） 成人头部 vessel vessel 血管 A tubular structure that contains, conveys body fluid, such as blood or lymph. UBERON:0000055 uberon A tubular structure that contains, conveys body fluid, such as blood or lymph. UBERON:0000055 uberon 包含传送体液如血液或淋巴液的管状结构。 anatomical wall anatomical wall 解剖壁 EMAPA:25036 FMA:82482 Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. UBERON:0000060 UBERON:0009915 galen:Wall in FMA, serosa is a wall organ wall organ wall uberon wall wall wall of organ wall of organ EMAPA:25036 FMA:82482 Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. UBERON:0000060 UBERON:0009915 galen:Wall in FMA, serosa is a wall organ wall organ wall uberon wall wall wall of organ wall of organ 器官墙(organ wall) 器官墙(organ wall) 器官墙(wall of organ) 器官墙(wall of organ) 在FMA中，绒毛膜是一层壁 壁 壁 毗邻器官腔的器官组件，其由器官组成层的最大聚集体构成。 anatomical structure anatomical structure 解剖结构 AAO:0010825 AAO:0010825 AEO:0000003 AEO:0000003 BILA:0000003 BILA:0000003 CARO:0000003 CARO:0000003 EHDAA2:0003003 EHDAA2:0003003 EMAPA:0 EMAPA:0 FBbt:00007001 FBbt:00007001 FMA:305751 FMA:305751 FMA:67135 FMA:67135 GAID:781 GAID:781 HAO:0000003 HAO:0000003 MA:0003000 MA:0003000 MESH:D000825 MESH:D000825 Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. TAO:0000037 TAO:0000037 TGMA:0001823 TGMA:0001823 UBERON:0000061 UBERON:0000061 VHOG:0001759 VHOG:0001759 WBbt:0000100 XAO:0003000 XAO:0003000 ZFA:0000037 ZFA:0000037 biological structure biological structure connected biological structure connected biological structure uberon uberon AAO:0010825 AEO:0000003 BILA:0000003 CARO:0000003 EHDAA2:0003003 EMAPA:0 FBbt:00007001 FMA:305751 FMA:67135 GAID:781 HAO:0000003 MA:0003000 MESH:D000825 Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. TAO:0000037 TGMA:0001823 UBERON:0000061 VHOG:0001759 WBbt:0000100 XAO:0003000 ZFA:0000037 biological structure biological structure connected biological structure connected biological structure uberon 材料解剖学实体，其具有由生物体自身基因组的协调表达产生的固有3D形状的单一连接结构。 生物结构 生物结构 连接生物结构 连接生物结构 organ part organ part 器官部分 A multicellular structure that is a part of an organ. AAO:0011124 AAO:0011124 EFO:0000635 EFO:0000635 FMA:82472 FMA:82472 UBERON:0000064 UBERON:0000064 cardinal organ part cardinal organ part currently defined in a very broad sense, may be replaced by more specific classes in the future regional part of organ regional part of organ uberon uberon A multicellular structure that is a part of an organ. AAO:0011124 EFO:0000635 FMA:82472 UBERON:0000064 cardinal organ part cardinal organ part currently defined in a very broad sense, may be replaced by more specific classes in the future regional part of organ regional part of organ uberon 主要器官部分 主要器官部分 器官区域部分 器官区域部分 是器官一部分的多细胞结构。 目前在很广泛的意义上定义，将来可能被更具体的类别所取代 subdivision of skeletal system Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. skeletal system part skeletal system subdivision external ectoderm external ectoderm 外胚层 (or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis EHDAA2:0001968 EHDAA:1494 EHDAA:350 EHDAA:4784 EHDAA:4790 EHDAA:4796 EHDAA:7860 EMAPA:16096 FMA:87656 The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. UBERON:0000076 UMLS:C1515087 merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) surface (external) ectoderm surface (external) ectoderm surface ectoderm surface ectoderm uberon (or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis EHDAA2:0001968 EHDAA:1494 EHDAA:350 EHDAA:4784 EHDAA:4790 EHDAA:4796 EHDAA:7860 EMAPA:16096 FMA:87656 The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. UBERON:0000076 UMLS:C1515087 merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) surface (external) ectoderm surface (external) ectoderm surface ectoderm surface ectoderm uberon (或外部外胚层)形成以下结构：口腔和鼻腔涎腺的皮肤上皮，以及口腔和鼻腔牙釉质的腺体--作为附注，牙本质和牙髓源于松果体和垂体晶状体和眼顶部外胚层嵴的角膜，该角膜诱导胚胎肢芽的发育。表皮上的感觉受体。 与非神经融合。 在脊椎动物中，外胚层有三部分：外胚层（也称为表面外胚层），神经外胚层（神经嵴和神经管） 从神经外胚层分离后不久开始增殖的外胚层表面（外部）层。 表面外胚层(surface ectoderm) 表面外胚层(surface ectoderm) 表面（外）胚层 表面（外）胚层 mixed endoderm/mesoderm-derived structure mixed endoderm/mesoderm-derived structure 混合内胚层/中胚层衍生结构 An anatomical structure that develops from the endoderm and the mesoderm. Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple UBERON:0000077 UBERON:0000077 uberon uberon An anatomical structure that develops from the endoderm and the mesoderm. Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple UBERON:0000077 uberon 从内胚层和中胚层发展而来的解剖结构。 用于查询目的分组术语。 注意发展关系正在改进，大多数结构应该从最多一层开始整体发展，但可能有多重贡献 male reproductive system male reproductive system 男性生殖系统 The organs associated with producing offspring in the gender that produces spermatozoa. genitalia of male organism male genital organ male genital system male genital tract male genitalia male genitals male organism genitalia male organism reproductive system male reproductive tract reproductive system of male organism systema genitale masculinum The organs associated with producing offspring in the gender that produces spermatozoa. genitalia of male organism male genital organ male genital system male genital tract male genitalia male genitals male organism genitalia male organism reproductive system male reproductive tract reproductive system of male organism systema genitale masculinum 在产生精子的类别中与产生后代有关的器官。 雄性生殖器(male genitalia) 雄性生殖器(male genitals) 雄性生殖器官 雄性生殖器生殖系统 雄性生殖系统 雄性生殖道(male genital tract) 雄性生殖道(male reproductive tract) 雄性生物体生殖器(genitalia of male organism) 雄性生物体生殖器(male organism genitalia) 雄性生物体生殖系统 neuron projection bundle A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. funiculus nerve fiber bundle neural fiber bundle anterior region of body anterior region of body 身体前部 excreta A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity AEO:0000184 BTO:0000491 EHDAA2_RETIRED:0003184 ENVO:02000022 FMA:9674 UBERON:0000174 UBERON:0000324 UBERON:0007550 excreted substance excretion galen:Excretion portion of excreted substance uberon waste substance blood blood 血 A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO] A fluid that is composed of blood plasma and erythrocytes. AAO:0000046 AAO:0000046 BTO:0000089 BTO:0000089 CALOHA:TS-0079 CALOHA:TS-0079 EFO:0000296 EFO:0000296 EHDAA2:0000176 EHDAA2:0000176 EHDAA:418 EHDAA:418 EMAPA:16332 EMAPA:16332 ENVO:02000027 ENVO:02000027 EV:0100047 EV:0100047 FMA:9670 FMA:9670 GAID:965 GAID:965 Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO] MA:0000059 MA:0000059 MESH:D001769 MESH:D001769 MIAA:0000315 MIAA:0000315 NCIT:C12434 OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG] TAO:0000007 TAO:0000007 This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. UBERON:0000178 UBERON:0000178 UMLS:C0005767 UMLS:C0005767 VHOG:0000224 VHOG:0000224 XAO:0000124 XAO:0000124 ZFA:0000007 ZFA:0000007 galen:Blood galen:Blood portion of blood portion of blood relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] uberon uberon vertebrate blood vertebrate blood whole blood whole blood A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO] A fluid that is composed of blood plasma and erythrocytes. AAO:0000046 BTO:0000089 CALOHA:TS-0079 EFO:0000296 EHDAA2:0000176 EHDAA:418 EMAPA:16332 ENVO:02000027 EV:0100047 FMA:9670 GAID:965 Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO] MA:0000059 MESH:D001769 MIAA:0000315 OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG] TAO:0000007 This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. UBERON:0000178 UMLS:C0005767 VHOG:0000224 XAO:0000124 ZFA:0000007 galen:Blood portion of blood relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] uberon vertebrate blood whole blood 一种复杂的细胞混合物，悬浮在液体基质中，将营养物质输送到细胞并去除废物。 (Source: BioGlossary, www.Biology-Text.com)[TAO] 全血 关系缺失:详细说明结缔组织的亚类(AAO:0000571)[AAO] 最近的发现强烈地表明，参与血细胞发育和功能的分子途径在脊椎动物和各种无脊椎动物门中是高度保守的。（...） 现在有充分的理由相信，在脊椎动物和无脊椎动物中，血细胞谱系从一种常见的祖细胞--原始血细胞--分化出来。[well established][VHOG] 由血浆和红细胞组成的液体 脊椎动物血液 这个类别不包括血液类似物，例如昆虫的血液类似物。 见UBERON:0000179血液淋巴液。 部分血液 高度特化的循环组织，其由悬浮在被称为血浆的流体介质中的几种细胞类型组成。 haemolymphatic fluid haemolymphatic fluid 血淋巴液 2009-04-08T04:38:19Z 2009-04-08T04:38:19Z CARO:0000081 CARO:0000081 Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. UBERON:0000179 UBERON:0000179 blood or blood analog blood or blood analog circulating fluid circulating fluid cjm cjm uberon uberon 2009-04-08T04:38:19Z CARO:0000081 Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. UBERON:0000179 blood or blood analog blood or blood analog circulating fluid circulating fluid cjm uberon 循环液 循环液 是血淋巴系统一部分的循环液。血液、淋巴液、间质液或其类似物。 血液或血液类似物 血液或血液类似物 blastula Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. blastosphere blastula embryo mucosa A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] AEO:0000199 BTO:0000886 CALOHA:TS-2031 EHDAA2_RETIRED:0003234 EV:0100382 FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately FMA:85355 FMA:85358 GAID:297 MESH:D009092 OpenCyc:Mx4rvmKNOpwpEbGdrcN5Y29ycA UBERON:0000344 UMLS:C0026724 galen:Mucosa mucosa of organ mucosa of organ mucosa of organ part mucosa of organ part mucosal mucosal region mucosal region mucous membrane mucous membrane organ mucosa organ mucosa region of mucosa region of mucosa tunica mucosa tunica mucosa uberon organism substance organism substance 生物体物质 AAO:0010839 AAO:0010839 AEO:0000004 AEO:0000004 BILA:0000004 BILA:0000004 CALOHA:TS-2101 CALOHA:TS-2101 CARO:0000004 CARO:0000004 EHDAA2:0003004 EHDAA2:0003004 EMAPA:35178 EMAPA:35178 FBbt:00007019 FBbt:00007019 FMA:9669 FMA:9669 HAO:0000004 HAO:0000004 MA:0002450 MA:0002450 Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. NCIT:C13236 SPD:0000008 SPD:0000008 TAO:0001487 TAO:0001487 TGMA:0001824 TGMA:0001824 UBERON:0000463 UBERON:0000463 VHOG:0001726 VHOG:0001726 XAO:0004001 XAO:0004001 ZFA:0001487 ZFA:0001487 body fluid or substance body fluid or substance body substance body substance galen:BodySubstance galen:BodySubstance organism substance organism substance portion of body substance portion of body substance portion of organism substance portion of organism substance uberon uberon AAO:0010839 AEO:0000004 BILA:0000004 CALOHA:TS-2101 CARO:0000004 EHDAA2:0003004 EMAPA:35178 FBbt:00007019 FMA:9669 HAO:0000004 MA:0002450 Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. SPD:0000008 TAO:0001487 TGMA:0001824 UBERON:0000463 VHOG:0001726 XAO:0004001 ZFA:0001487 body fluid or substance body fluid or substance body substance body substance galen:BodySubstance organism substance organism substance portion of body substance portion of body substance portion of organism substance portion of organism substance uberon 体液或物质 体液或物质 气态、液态、半固态或固态的材料解剖学实体；由解剖结构产生，或由吸入和摄入物质产生，这些物质在通过身体时已经被解剖结构修饰。 生物体物质 生物体物质 生物体物质的一部分 生物体物质的一部分 身体物质 身体物质 身体物质的一部分 身体物质的一部分 anatomical space anatomical space 解剖空间 AAO:0010110 AEO:0000005 BILA:0000005 CARO:0000005 EHDAA2:0003005 FBbt:00007017 FMA:5897 HAO:0000005 Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. TAO:0001668 TGMA:0001825 UBERON:0000464 UMLS:C0524461 VHOG:0001728 XAO:0003190 ZFA:0001643 anatomical spaces anatomical spaces lumen lumen lumen space lumen space space space uberon AAO:0010110 AEO:0000005 BILA:0000005 CARO:0000005 EHDAA2:0003005 FBbt:00007017 FMA:5897 HAO:0000005 Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. TAO:0001668 TGMA:0001825 UBERON:0000464 UMLS:C0524461 VHOG:0001728 XAO:0003190 ZFA:0001643 anatomical spaces anatomical spaces lumen lumen lumen space lumen space space space uberon 三维非物质解剖学实体，由形态发生或其他生理过程产生；被一个或多个解剖结构包围；包含一种或多种有机体物质或解剖结构。 内腔 内腔 内腔空间 内腔空间 空间 空间 解剖空间 解剖空间 material anatomical entity material anatomical entity 物质解剖实体 AAO:0010264 AAO:0010264 AEO:0000006 AEO:0000006 Anatomical entity that has mass. BILA:0000006 BILA:0000006 CARO:0000006 CARO:0000006 EHDAA2:0003006 EHDAA2:0003006 FBbt:00007016 FBbt:00007016 FMA:67165 FMA:67165 HAO:0000006 HAO:0000006 TAO:0001836 TAO:0001836 TGMA:0001826 TGMA:0001826 UBERON:0000465 UBERON:0000465 VHOG:0001721 VHOG:0001721 uberon uberon AAO:0010264 AEO:0000006 Anatomical entity that has mass. BILA:0000006 CARO:0000006 EHDAA2:0003006 FBbt:00007016 FMA:67165 HAO:0000006 TAO:0001836 TGMA:0001826 UBERON:0000465 VHOG:0001721 uberon 有质量的解剖学实体。 immaterial anatomical entity immaterial anatomical entity 非物质解剖实体 AAO:0010265 AEO:0000007 Anatomical entity that has no mass. BILA:0000007 CARO:0000007 EHDAA2:0003007 FBbt:00007015 FMA:67112 HAO:0000007 TAO:0001835 TGMA:0001827 UBERON:0000466 VHOG:0001727 immaterial physical anatomical entity immaterial physical anatomical entity uberon AAO:0010265 AEO:0000007 Anatomical entity that has no mass. BILA:0000007 CARO:0000007 EHDAA2:0003007 FBbt:00007015 FMA:67112 HAO:0000007 TAO:0001835 TGMA:0001827 UBERON:0000466 VHOG:0001727 immaterial physical anatomical entity immaterial physical anatomical entity uberon 没有质量的解剖实体。 非物质的物理解剖学实体 非物质的物理解剖学实体 anatomical system anatomical system 解剖系统 Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. anatomical systems body system connected anatomical system organ system system Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. anatomical systems body system connected anatomical system organ system system 器官系统 多细胞的，连接的解剖结构，具有多个器官作为它的部分，并且它的部分一起工作以实现一些共同的功能。 系统 解剖系统 身体系统 连接的解剖系统 multicellular organism multicellular organism 多细胞生物 AAO:0010026 AEO:0000191 Anatomical structure that is an individual member of a species and consists of more than one cell. BILA:0000012 BSA:0000038 BTO:0000042 CARO:0000012 EFO:0002906 EHDAA2:0003103 EHDAA2:0003191 EHDAA:1 EHDAA:9178 EMAPA:25765 EV:0100016 FBbt:00000001 FMA:256135 HAO:0000012 Koerper Koerper TADS:0000001 TAO:0001094 TGMA:0001832 TODO - split body and mc organism? body continues after death stage UBERON:0000468 VHOG:0000671 WBbt:0007833 XAO:0003004 ZFA:0001094 animal animal body body galen:Organism multi-cellular organism multi-cellular organism ncithesaurus:Whole_Organism organism organism organismal uberon whole body whole body whole organism whole organism AAO:0010026 AEO:0000191 Anatomical structure that is an individual member of a species and consists of more than one cell. BILA:0000012 BSA:0000038 BTO:0000042 CARO:0000012 EFO:0002906 EHDAA2:0003103 EHDAA2:0003191 EHDAA:1 EHDAA:9178 EMAPA:25765 EV:0100016 FBbt:00000001 FMA:256135 HAO:0000012 Koerper Koerper TADS:0000001 TAO:0001094 TGMA:0001832 TODO - split body and mc organism? body continues after death stage UBERON:0000468 VHOG:0000671 WBbt:0007833 XAO:0003004 ZFA:0001094 animal animal body body galen:Organism multi-cellular organism multi-cellular organism ncithesaurus:Whole_Organism organism organism organismal uberon whole body whole body whole organism whole organism 全身 全身 动物 动物 多细胞生物 多细胞生物 待办事项 - 拆分身体和MC机体？ 死后身体继续 整个生物体 整个生物体 是一个物种的个体成员并由多个细胞组成的解剖结构。 生物 生物 生物体的 身体 身体 躯体 躯体 female reproductive system The organs and associated structures associated with bearing offspring in a female animal. female genital system female genital tract female genitalia female genitals female organism genitalia female organism reproductive system female reproductive tract genitalia of female organism gynaecological tissue reproductive system of female organism systema genitale femininum organism subdivision organism subdivision 生物细分 AAO:0010053 AEO:0000032 Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. BILA:0000032 CALOHA:TS-2084 CARO:0000032 EFO:0000808 EHDAA2:0003032 EMAPA:36031 FBbt:00007009 FMA:7153 HAO:0000032 MA:0002433 MAT:0000293 MESH:D001829 MIAA:0000293 OpenCyc:Mx4rvViAHJwpEbGdrcN5Y29ycA Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency TAO:0001308 TGMA:0001840 UBERON:0000475 UMLS:C0229962 VHOG:0001758 XAO:0003013 ZFA:0001308 anatomic region anatomic region body part body part body region body region cardinal body part cardinal body part galen:BodyPart uberon AAO:0010053 AEO:0000032 Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. BILA:0000032 CALOHA:TS-2084 CARO:0000032 EFO:0000808 EHDAA2:0003032 EMAPA:36031 FBbt:00007009 FMA:7153 HAO:0000032 MA:0002433 MAT:0000293 MESH:D001829 MIAA:0000293 OpenCyc:Mx4rvViAHJwpEbGdrcN5Y29ycA Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency TAO:0001308 TGMA:0001840 UBERON:0000475 UMLS:C0229962 VHOG:0001758 XAO:0003013 ZFA:0001308 anatomic region anatomic region body part body part body region body region cardinal body part cardinal body part galen:BodyPart uberon 主要身体部分 主要身体部分 反映CARO2。 待办事项 - 检查包括FMA“主要身体部位在这里”，并检查子项的一致性 解剖区域 解剖区域 解剖结构是整个有机体的细分，由多个解剖系统的组分组成，大部分由一个连续的体壁区域包围。 身体的一部分 身体的一部分 身体部位 身体部位 acellular anatomical structure acellular anatomical structure 脱细胞解剖结构 Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. acellular anatomical structures Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. acellular anatomical structures 无细胞解剖结构 由细胞部分和细胞物质组成的解剖结构并不构成一个细胞或组织。 anatomical cluster anatomical cluster 解剖簇 AAO:0010009 AEO:0000041 Anatomical group that has its parts adjacent to one another. BILA:0000041 CARO:0000041 EHDAA2:0003041 FBbt:00007277 FMA:49443 HAO:0000041 TADS:0000605 TAO:0001478 TGMA:0001842 UBERON:0000477 VHOG:0001737 Will be obsoleted in CARO v2 [https://github.com/obophenotype/caro/issues/3] XAO:0003160 ZFA:0001478 uberon AAO:0010009 AEO:0000041 Anatomical group that has its parts adjacent to one another. BILA:0000041 CARO:0000041 EHDAA2:0003041 FBbt:00007277 FMA:49443 HAO:0000041 TADS:0000605 TAO:0001478 TGMA:0001842 UBERON:0000477 VHOG:0001737 Will be obsoleted in CARO v2 [https://github.com/obophenotype/caro/issues/3] XAO:0003160 ZFA:0001478 uberon 将在CARO v2中过时[https://github.com/obophenotype/caro/issues/3] 解剖集合的部分彼此相邻。 extraembryonic structure extraembryonic structure 胚外结构 A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. AAO:0010020 AAO:0010020 AEO:0000042 AEO:0000042 BILA:0000042 BILA:0000042 CALOHA:TS-2119 CALOHA:TS-2119 CARO:0000042 CARO:0000042 EHDAA2:0003042 EHDAA2:0003042 EHDAA:46 EHDAA:46 FBbt:00005835 FBbt:00005835 FMA:85537 FMA:85537 HAO:0000042 HAO:0000042 NCIT:C34055 TAO:0000020 TAO:0000020 TGMA:0001843 TGMA:0001843 UBERON:0000478 UBERON:0000478 UMLS:C1282438 UMLS:C1282438 VHOG:0000292 VHOG:0000292 XAO:0004005 XAO:0004005 ZFA:0000020 ZFA:0000020 extra-embryonic structure extra-embryonic structure extraembryonic structures extraembryonic structures extraembryonic tissue extraembryonic tissue see also conceptus extraembryonic component in EHDAA2. uberon uberon A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. AAO:0010020 AEO:0000042 BILA:0000042 CALOHA:TS-2119 CARO:0000042 EHDAA2:0003042 EHDAA:46 FBbt:00005835 FMA:85537 HAO:0000042 TAO:0000020 TGMA:0001843 UBERON:0000478 UMLS:C1282438 VHOG:0000292 XAO:0004005 ZFA:0000020 extra-embryonic structure extra-embryonic structure extraembryonic structures extraembryonic structures extraembryonic tissue extraembryonic tissue see also conceptus extraembryonic component in EHDAA2. uberon 一种与胚胎有关的多细胞解剖结构，来源于胚胎发育的合子，但不影响胚胎发育后的胚体或作为同一生物体一部分的结构。 参见EHDAA2中的概念胚外组分。 胚外组织(extraembryonic tissue) 胚外组织(extraembryonic tissue) 胚外结构(extra-embryonic structure) 胚外结构(extra-embryonic structure) 胚外结构(extraembryonic structures) 胚外结构(extraembryonic structures) tissue tissue 组织 AAO:0000607 AAO:0000607 AAO:0010054 AAO:0010054 AEO:0000043 AEO:0000043 BILA:0000043 BILA:0000043 CALOHA:TS-2090 CALOHA:TS-2090 CARO:0000043 CARO:0000043 EHDAA2:0003043 EHDAA2:0003043 EMAPA:35868 EMAPA:35868 FBbt:00007003 FBbt:00007003 FMA:9637 FMA:9637 HAO:0000043 HAO:0000043 MA:0003002 MA:0003002 MESH:D014024 MESH:D014024 Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. NCIT:C12801 TAO:0001477 TAO:0001477 TGMA:0001844 TGMA:0001844 UBERON:0000479 UBERON:0000479 UMLS:C0040300 UMLS:C0040300 VHOG:0001757 VHOG:0001757 WBbt:0005729 WBbt:0005729 XAO:0003040 XAO:0003040 ZFA:0001477 ZFA:0001477 changed label and definition to reflect CARO2 galen:Tissue galen:Tissue portion of tissue portion of tissue simple tissue simple tissue tissue portion tissue portion uberon uberon AAO:0000607 AAO:0010054 AEO:0000043 BILA:0000043 CALOHA:TS-2090 CARO:0000043 EHDAA2:0003043 EMAPA:35868 FBbt:00007003 FMA:9637 HAO:0000043 MA:0003002 MESH:D014024 Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. TAO:0001477 TGMA:0001844 UBERON:0000479 UMLS:C0040300 VHOG:0001757 WBbt:0005729 XAO:0003040 ZFA:0001477 changed label and definition to reflect CARO2 galen:Tissue portion of tissue portion of tissue simple tissue simple tissue tissue portion tissue portion uberon 多细胞解剖结构，由一个或几个类型的许多细胞组成，排列在细胞外基质中，使得它们的远程组织至少部分是其短程组织的重复。 改变标签和定义以反映CARO2 简单组织 简单组织 组织部分(portion of tissue) 组织部分(portion of tissue) 组织部分(tissue portion) 组织部分(tissue portion) multi-tissue structure multi-tissue structure 多组织结构 AAO:0010048 AEO:0000055 Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. BILA:0000055 CARO:0000055 EHDAA2:0003055 FBbt:00007010 HAO:0000055 TAO:0001488 TGMA:0001847 UBERON:0000481 VHOG:0001762 XAO:0003037 ZFA:0001488 multi-tissue structures multi-tissue structures uberon AAO:0010048 AEO:0000055 Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. BILA:0000055 CARO:0000055 EHDAA2:0003055 FBbt:00007010 HAO:0000055 TAO:0001488 TGMA:0001847 UBERON:0000481 VHOG:0001762 XAO:0003037 ZFA:0001488 multi-tissue structures multi-tissue structures uberon 具有至少两种不同类型的组织的两个或更多个部分并且通过特定的形态发生过程形成一个单一的不同类型的结构单元的解剖结构，所述结构单元由不同类型的其他不同结构单元的真实边界划分。 多组织结构 多组织结构 epithelium epithelium 上皮 AAO:0000144 AAO:0000144 AAO:0010055 AAO:0010055 AEO:0000066 AEO:0000066 BILA:0000066 BILA:0000066 BTO:0000416 BTO:0000416 CALOHA:TS-0288 CALOHA:TS-0288 CARO:0000066 CARO:0000066 EHDAA2:0003066 EHDAA2:0003066 EMAPA:32738 EMAPA:32738 FBbt:00007005 FBbt:00007005 FMA:9639 FMA:9639 GAID:402 GAID:402 HAO:0000066 HAO:0000066 MA:0003060 MA:0003060 MESH:D004848 MESH:D004848 NCIT:C12710 Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. TAO:0001486 TAO:0001486 The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG] UBERON:0000483 UBERON:0000483 UMLS:C0014609 UMLS:C0014609 VHOG:0000387 VHOG:0000387 XAO:0003045 XAO:0003045 ZFA:0001486 ZFA:0001486 epithelial epithelial tissue epithelial tissue portion of epithelium portion of epithelium uberon uberon AAO:0000144 AAO:0010055 AEO:0000066 BILA:0000066 BTO:0000416 CALOHA:TS-0288 CARO:0000066 EHDAA2:0003066 EMAPA:32738 FBbt:00007005 FMA:9639 GAID:402 HAO:0000066 MA:0003060 MESH:D004848 Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. TAO:0001486 The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG] UBERON:0000483 UMLS:C0014609 VHOG:0000387 XAO:0003045 ZFA:0001486 epithelial epithelial tissue epithelial tissue portion of epithelium portion of epithelium uberon 上皮的 上皮组织 上皮组织 上皮部分 上皮部分 后生动物组织的两种基本类型是上皮和结缔组织。最简单的后生动物和许多原始无脊椎动物的发育阶段仅由这两层组成。因此，上皮和结缔组织可能是后生动物的主要（原始）组织，两者在动物的功能组织中都是重要的。[well established][VHOG] 组织的一部分，由一层或多层上皮细胞通过细胞连接相互连接，并位于一个基底层的下方。例如：简单的鳞状上皮、腺状立方上皮、移行上皮、肌上皮[CARO]。 simple columnar epithelium AAO:0010063 AEO:0000068 BILA:0000068 CARO:0000068 EHDAA2_RETIRED:0003068 FBbt:00007027 FMA:45567 HAO:0000068 NCIT:C33552 TAO:0001496 UBERON:0000485 UMLS:C0836135 Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA] XAO:0004008 ZFA:0001496 columnar epithelium columnar epithlium epithelium simplex columnare simple columnar epithelia simple columnar epithelium uberon multilaminar epithelium multilaminar epithelium 多层上皮 AAO:0010059 AEO:0000069 BILA:0000069 BTO:0002074 CARO:0000069 EHDAA2:0003069 Epithelium that consists of more than one layer of epithelial cells.[CARO] Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] FMA:45562 HAO:0000069 TAO:0001494 UBERON:0000486 UMLS:C0682575 XAO:0004006 ZFA:0001494 laminated epithelium laminated epithelium stratified epithelium stratified epithelium uberon AAO:0010059 AEO:0000069 BILA:0000069 BTO:0002074 CARO:0000069 EHDAA2:0003069 Epithelium that consists of more than one layer of epithelial cells.[CARO] Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] FMA:45562 HAO:0000069 TAO:0001494 UBERON:0000486 UMLS:C0682575 XAO:0004006 ZFA:0001494 laminated epithelium laminated epithelium stratified epithelium stratified epithelium uberon 复层上皮(laminated epithelium) 复层上皮(laminated epithelium) 复层上皮(stratified epithelium) 复层上皮(stratified epithelium) 由多于一层的上皮细胞组成的上皮。[CARO] 由多于一层的上皮细胞组成的上皮，这些上皮细胞可能与基底膜接触也可能不接触。实例：角化复层鳞状上皮，纤毛层状柱状上皮。[FMA] atypical epithelium AAO:0010057 AEO:0000071 BILA:0000071 CARO:0000071 EHDAA2:0003071 Epithelium that consists of epithelial cells not arranged in one ore more layers. FMA:61741 HAO:0000071 TAO:0001493 UBERON:0000488 XAO:0004004 ZFA:0001493 atypical epithelia heterogenous epithelium uberon unilaminar epithelium unilaminar epithelium 单层上皮 AAO:0010062 AAO:0010062 AEO:0000073 AEO:0000073 BILA:0000073 BILA:0000073 BTO:0002073 BTO:0002073 CARO:0000073 CARO:0000073 EHDAA2:0003073 EHDAA2:0003073 Epithelium that consists of a single layer of epithelial cells.[CARO] Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] FMA:45561 FMA:45561 HAO:0000073 HAO:0000073 NCIT:C33554 TAO:0001495 TAO:0001495 UBERON:0000490 UBERON:0000490 UMLS:C0682574 UMLS:C0682574 XAO:0004007 XAO:0004007 ZFA:0001495 ZFA:0001495 consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable simple epithelium simple epithelium uberon uberon unilaminar epithelia unilaminar epithelia AAO:0010062 AEO:0000073 BILA:0000073 BTO:0002073 CARO:0000073 EHDAA2:0003073 Epithelium that consists of a single layer of epithelial cells.[CARO] Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] FMA:45561 HAO:0000073 TAO:0001495 UBERON:0000490 UMLS:C0682574 XAO:0004007 ZFA:0001495 consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable simple epithelium simple epithelium uberon unilaminar epithelia unilaminar epithelia 单层上皮(simple epithelium) 单层上皮(simple epithelium) 单层上皮(unilaminar epithelia) 单层上皮(unilaminar epithelia) 由单层上皮细胞组成的上皮。[CARO] 由单层上皮细胞组成的上皮。例如：内皮、间皮、腺体鳞状上皮。[FMA] 考虑在单层和多层之间添加不相交公理 - 但是请注意，这将使得EHDAA2:0003244（绒毛膜滋养层）不可满足 thoracic segment of trunk thoracic segment of trunk 躯干胸段 Subdivision of trunk that lies between the head and the abdomen. anterior subdivision of trunk thorax upper body upper trunk Subdivision of trunk that lies between the head and the abdomen. anterior subdivision of trunk thorax upper body upper trunk 上半身 上身 位于头部和腹部之间的躯干的细分。 胸部 躯干前部细分 embryo embryo 胚胎 AAO:0011035 AEO:0000169 Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. BILA:0000056 BSA:0000039 BTO:0000379 CALOHA:TS-0229 EFO:0001367 EHDAA2:0000002 EHDAA2_RETIRED:0003236 EHDAA:38 EMAPA:16039 FBbt:00000052 FMA:69068 GAID:963 MAT:0000226 MESH:D004622 MIAA:0000019 OGEM:000001 Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo OpenCyc:Mx4rwP1ceZwpEbGdrcN5Y29ycA UBERON:0000922 UMLS:C0013935 VHOG:0001766 XAO:0000113 ZFA:0000103 developing organism developing organism developmental tissue developmental tissue embryonic embryonic organism embryonic organism uberon AAO:0011035 AEO:0000169 Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. BILA:0000056 BSA:0000039 BTO:0000379 CALOHA:TS-0229 EFO:0001367 EHDAA2:0000002 EHDAA2_RETIRED:0003236 EHDAA:38 EMAPA:16039 FBbt:00000052 FMA:69068 GAID:963 MAT:0000226 MESH:D004622 MIAA:0000019 OGEM:000001 Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo OpenCyc:Mx4rwP1ceZwpEbGdrcN5Y29ycA UBERON:0000922 UMLS:C0013935 VHOG:0001766 XAO:0000113 ZFA:0000103 developing organism developing organism developmental tissue developmental tissue embryonic embryonic organism embryonic organism uberon 包括以分裂为特征的生长和分化的早期阶段的有机体，基本组织的建立，以及原始器官和器官系统形成的解剖实体。例如，对哺乳动物而言，这个过程将从合子形成开始，到出生结束。对于昆虫，这个过程将从合子形成开始并以幼虫孵化结束。对于植物合子胚，这将从合子形成到种子休眠结束。对于植物营养体胚胎，这可能是从胚胎的细胞或细胞群体的初始确定直到胚胎变成独立于母体植物的时候。 发育的生物体 发育的生物体 发育组织 发育组织 在ZFA中弃用。注意，胚胎不属于胚胎结构--胚胎结构只是胚胎的一部分。 胚胎生物体 胚胎生物体 胚胎的 germ layer germ layer 胚层 A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. embryonic germ layer embryonic germ layers embryonic tissue germinal layer primary germ layer A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. embryonic germ layer embryonic germ layers embryonic tissue germinal layer primary germ layer 作为细胞分化的早期步骤，在动物胚胎的早期发育过程中原肠胚形成过程中产生的细胞层与其他这样的细胞层不同。三种类型的胚层是内胚层、外胚层和中胚层。 初生胚层 生发层 胚胎组织 胚胎胚层(embryonic germ layer) 胚胎胚层(embryonic germ layers) ectoderm ectoderm 外胚层 Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. embryonic ectoderm Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. embryonic ectoderm 原始胚层是胚胎的三个胚层的外层，并产生表皮和神经组织。 胚胎外胚层 endoderm endoderm 内胚层 Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. entoderm Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. entoderm 内胚层 初生胚层位于远离胚胎表面，并产生内部组织如肠。 heart heart 心脏 A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. AAO:0010210 As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG] BILA:0000020 BTO:0000562 Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO] CALOHA:TS-0445 EFO:0000815 EHDAA2:0000738 EHDAA:420 EMAPA:16105 EV:0100018 FMA:7088 GAID:174 Herz@de Herz@de MA:0000072 MAT:0000036 MESH:D006321 MIAA:0000036 OpenCyc:Mx4rvVjvDpwpEbGdrcN5Y29ycA Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO] TAO:0000114 Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" http://dx.doi.org/10.1101/gad.1485706 UBERON:0000948 UMLS:C0018787 VHOG:0000276 XAO:0000064 ZFA:0000114 branchial heart branchial heart cardiac cardium cardium chambered heart chambered heart galen:Heart relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO] uberon vertebrate heart vertebrate heart A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. AAO:0010210 As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG] BILA:0000020 BTO:0000562 Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO] CALOHA:TS-0445 EFO:0000815 EHDAA2:0000738 EHDAA:420 EMAPA:16105 EV:0100018 FMA:7088 GAID:174 Herz@de Herz@de MA:0000072 MAT:0000036 MESH:D006321 MIAA:0000036 OpenCyc:Mx4rvVjvDpwpEbGdrcN5Y29ycA Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO] TAO:0000114 Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" http://dx.doi.org/10.1101/gad.1485706 UBERON:0000948 UMLS:C0018787 VHOG:0000276 XAO:0000064 ZFA:0000114 branchial heart branchial heart cardiac cardium cardium chambered heart chambered heart galen:Heart relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO] uberon vertebrate heart vertebrate heart 关系类型变化:区分_于外侧板中胚层(AAO:0010574)变化为:发展_自外侧板中胚层(UBERON:0003081)[AAO] 分类注释：“海鞘管状的心脏缺乏腔室......蜕变后，海鞘的心脏形成一个简单的管状结构，有单层的肌上皮，该肌上皮与单层的心包壁连在一起。它缺少心室和心内膜....有腔心脏的创新是脊椎动物进化的一个关键事件，因为有腔的心脏产生高压的单向血流，这是大型脊椎动物有效血液供应的关键需求......所有现存的脊椎动物都有两个或两个以上的腔室（Moorman and Christoffels 2003）“ http://dx.doi.org/10.1101/gad.1485706 在由心肌腔室组成的脊椎动物心血管系统中发现的肌源性肌肉循环器官。这是主要的循环器官。 心肌 心脏的 正如所指出的，鸟类和哺乳动物的心脏有四个腔室，它们起源于鱼心的两个腔室（心房和心室）。[well established][VHOG] 脊椎动物心脏 脊椎动物心脏 腔心 腔心 血泵器官包括四个腔：静脉窦，心房，心室和延髓动脉[TAO]。 负责泵送血液的循环系统的一部分；由三个室--两个心房和一个心室组成。[AAO] 鳃心 鳃心 skeletal joint Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. articular joint articulation joint joints penis A intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination penes phallus reproductive system reproductive system 生殖系统(reproductive system) Anatomical system that has as its parts the organs concerned with reproduction. Geschlechtsorgan animal reproductive system genital system genital tract genitalia organa genitalia reproductive tissue reproductive tract systemata genitalia Anatomical system that has as its parts the organs concerned with reproduction. Geschlechtsorgan animal reproductive system genital system genital tract genitalia organa genitalia reproductive tissue reproductive tract systemata genitalia 动物生殖系统 器官生殖器 有与生殖器有关的器官部分的解剖系统。 生殖器 生殖器(Geschlechtsorgan) 生殖系统(genital system) 生殖组织 生殖道(genital tract) 生殖道(reproductive tract) 系统性生殖器 gonad gonad 性腺(gonad) AAO:0000213 Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO] BILA:0000123 BSA:0000079 BTO:0000534 EMAPA:16857 EMAPA:17383 Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG] FBbt:00004858 FMA xref is a 'general anatomical term' FMA:18250 GAID:368 HAO:0000379 MA:0002420 MESH:D006066 OpenCyc:Mx4rwQvdiZwpEbGdrcN5Y29ycA Reproductive organ that produces and releases eggs (ovary) or sperm (testis). TAO:0000413 The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO] UBERON:0000991 UMLS:C0018067 VHOG:0000397 WBbt:0005175 XAO:0003146 ZFA:0000413 gonada gonada gonadal gonads gonads uberon AAO:0000213 Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO] BILA:0000123 BSA:0000079 BTO:0000534 EMAPA:16857 EMAPA:17383 Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG] FBbt:00004858 FMA xref is a 'general anatomical term' FMA:18250 GAID:368 HAO:0000379 MA:0002420 MESH:D006066 OpenCyc:Mx4rwQvdiZwpEbGdrcN5Y29ycA Reproductive organ that produces and releases eggs (ovary) or sperm (testis). TAO:0000413 The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO] UBERON:0000991 UMLS:C0018067 VHOG:0000397 WBbt:0005175 XAO:0003146 ZFA:0000413 gonada gonada gonadal gonads gonads uberon FMA xref是"一般解剖学术语" 产生和释放卵子（卵巢）或精子（睾丸）的生殖器官。 产生和释放卵子（卵巢）或精子（睾丸）的生殖系统部分。 产生配子和由垂体促性腺激素控制的某些性激素的解剖结构。 对不同脊椎动物种类的研究表明，成年生殖腺的形态在不同的系统发生分类中非常相似。然而令人惊讶的是，用来创造相似器官的细胞和分子程序并不是进化上保守的。[uncertain][VHOG] 性腺 性腺(gonada) 性腺(gonada) 性腺(gonads) 性腺(gonads) skin epidermis (...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG] A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO] AAO:0000143 BTO:0000404 CALOHA:TS-0283 EFO:0000954 EMAPA:17528 EV:0100153 FMA:70596 GAID:932 MA:0000153 MAT:0000154 MESH:D004817 MIAA:0000154 TAO:0000105 The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO] The outer epithelial layer of the skin that is superficial to the dermis. UBERON:0001003 UMLS:C0014520 VHOG:0000077 XAO:0000028 ZFA:0000105 Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes). epidermal epidermis epidermis relationship loss: subclass external integument structures (AAO:0000961)[AAO] skin skin uberon vertebrate epidermis vertebrate epidermis digestive system digestive system 消化系统(digestive system) Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. alimentary system alimentary tract gastrointestinal system gut Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. alimentary system alimentary tract gastrointestinal system gut 有用于摄入、消化和吸收食物和排出残余废物的器官部分的解剖系统。 消化系统(alimentary system) 消化道 肠 胃肠系统 adipose tissue AAO:0000001 AEO:000020 Adipose tissue is unique to vertebrates. It is found in mostmammals, birds, reptiles and amphibians, and a variety is found in some species of fish. Furthermore, in insects the fat body found in larvae as well as in adults shares some homology with adipose tissue.[well established][VHOG] BTO:0001487 CALOHA:TS-0013 Connective tissue in which fat is stored.[TAO] EFO:0000790 EHDAA2:0003120 EMAPA:35112 EV:0100381 FMA:20110 GAID:920 In humans, adipose tissue is located beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue. Adipose tissue is found in specific locations, which are referred to as adipose depots. Adipose tissue contains several cell types, with the highest percentage of cells being adipocytes, which contain fat droplets. Other cell types include fibroblasts, macrophages, and endothelial cells. Adipose tissue contains many small blood vessels.; Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdomen, surrounding the kidney, and, when massive, extend into the pelvis. The mesenteric depot forms a glue-like web that supports the intestines, and the omental depot, which originates near the stomach and spleen, and, when massive, extends into the ventral abdomen. MA:0000009 MAT:0000015 MESH:D000273 MIAA:0000015 OpenCyc:Mx4rvVjc_ZwpEbGdrcN5Y29ycA Portion of connective tissue composed of adipocytes enmeshed in areolar tissue TAO:0002134 Tissue that contains adipocytes, used for cushioning, thermal insulation, lubrication (primarily in the pericardium) and energy storage.[AAO] UBERON:0001013 UMLS:C0001527 VHOG:0001284 XAO:0003049 ZFA:0005345 adipose adipose adipose bodyfat bodyfat fat fat fat tissue fat tissue fatty depot fatty depot fatty tissue fatty tissue galen:FattyTissue in FMA this is dense irregular connective tissue relationship loss: subclass connective tissue proper (AAO:0000099)[AAO] uberon musculature musculature 肌肉组织 A subdivision of the muscular system corresponding to a subdisivision of an organism. AAO:0011066 BTO:0000887 EFO:0001949 EMAPA:32715 EMAPA:35577 FMA:32558 In FMA this is classified as a set of organs. ZFA musculature system has subtypes, so it is classified here. WBbt muscular system has subtypes so it goes here. Note that we use the MA term set of skeletal muscles here as it seems most appropriate (*not* MA:musculature). AAO is generally confused here. MA:0000165 OpenCyc:Mx4rvVjmr5wpEbGdrcN5Y29ycA TAO:0000548 UBERON:0001015 UMLS:C0026845 VSAO:0005038 WBbt:0005737 ZFA:0000548 muscle group muscle group muscle system muscle system muscles muscles muscles set muscles set musculature musculature musculature system musculature system musculi musculi set of muscles set of muscles set of skeletal muscles set of skeletal muscles uberon A subdivision of the muscular system corresponding to a subdisivision of an organism. AAO:0011066 BTO:0000887 EFO:0001949 EMAPA:32715 EMAPA:35577 FMA:32558 In FMA this is classified as a set of organs. ZFA musculature system has subtypes, so it is classified here. WBbt muscular system has subtypes so it goes here. Note that we use the MA term set of skeletal muscles here as it seems most appropriate (*not* MA:musculature). AAO is generally confused here. MA:0000165 OpenCyc:Mx4rvVjmr5wpEbGdrcN5Y29ycA TAO:0000548 UBERON:0001015 UMLS:C0026845 VSAO:0005038 WBbt:0005737 ZFA:0000548 muscle group muscle group muscle system muscle system muscles muscles muscles set muscles set musculature musculature musculature system musculature system musculi musculi set of muscles set of muscles set of skeletal muscles set of skeletal muscles uberon 一套肌肉 一套肌肉 一套骨骼肌肉 一套骨骼肌肉 在FMA中，这被分类为一组器官。ZFA肌肉系统有亚型，故在此分类。WBbt肌肉系统有亚型，所以它在这里。注意，我们在这里使用骨骼肌的MA术语集合，因为它似乎是最适当的(*not* MA:musculature)。AAO在这里通常是混淆的。 肌 肌 肌肉 肌肉 肌肉系统(muscle system) 肌肉系统(muscle system) 肌肉系统(musculature system) 肌肉系统(musculature system) 肌肉系统的一个细分，对应于一个有机体的小细分。 肌肉组(muscle group) 肌肉组(muscle group) 肌肉组(muscles set) 肌肉组(muscles set) 肌肉组织 肌肉组织 nervous system nervous system 神经系统(nervous system) A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] AAO:0000324 Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] BILA:0000079 BTO:0001484 CALOHA:TS-1313 EFO:0000802 EHDAA2:0001246 EHDAA:826 EMAPA:16469 EV:0100162 FBbt:00005093 FMA:7157 GAID:466 MA:0000016 MAT:0000026 MESH:D009420 MIAA:0000026 Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] OpenCyc:Mx4rvViT_pwpEbGdrcN5Y29ycA TAO:0000396 The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. UBERON:0001016 UMLS:C0027763 VHOG:0000402 WBbt:0005735 XAO:0000177 ZFA:0000396 nerve net nerve net nervous neural neurological system neurological system systema nervosum systema nervosum uberon A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] AAO:0000324 Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] BILA:0000079 BTO:0001484 CALOHA:TS-1313 EFO:0000802 EHDAA2:0001246 EHDAA:826 EMAPA:16469 EV:0100162 FBbt:00005093 FMA:7157 GAID:466 MA:0000016 MAT:0000026 MESH:D009420 MIAA:0000026 Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] OpenCyc:Mx4rvViT_pwpEbGdrcN5Y29ycA TAO:0000396 The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. UBERON:0001016 UMLS:C0027763 VHOG:0000402 WBbt:0005735 XAO:0000177 ZFA:0000396 nerve net nerve net nervous neural neurological system neurological system systema nervosum systema nervosum uberon 由神经体和神经纤维组成的解剖学系统，其调节身体对外部和内部刺激的反应。[AAO] 由神经元和神经胶质细胞组成的身体调控系统。神经系统分为两部分，中枢神经系统(CNS)和外周神经系统(PNS)。（来源：BioGlossary，www.Biology-Text.com）[TAO] 神经 神经系统(neurological system) 神经系统(neurological system) 神经系统是主要包含神经元和神经胶质细胞的器官系统。在双侧对称的生物体中，它被安排在一个连接到中心体的树状结构网络中。神经系统的主要功能是调节和控制身体功能，接受感官输入，处理这些信息，并产生行为[CUMBO]。 神经系统是由真后生动物的祖先进化而来的。[well established][VHOG] 神经紧张 神经网 神经网 系统性神经 系统性神经 nerve An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. nerves neural subtree peripheral nerve strand of hair A filament, mostly protein, that grows from follicles found in the dermis[WP]. BTO:0001501 BTO:0001501 CALOHA:TS-0430 CALOHA:TS-0430 EFO:0000958 EFO:0000958 EMAPA:18769 EMAPA:18769 EV:0100157 EV:0100157 FMA:53667 FMA:53667 GAID:71 GAID:71 MA:0000155 MA:0000155 MAT:0000160 MAT:0000160 MESH:D006197 MESH:D006197 MIAA:0000160 MIAA:0000160 NCIT:C32705 OpenCyc:Mx4rvVjOX5wpEbGdrcN5Y29ycA-Mp88EdaAAACgycbRww OpenCyc:Mx4rvVjOX5wpEbGdrcN5Y29ycA-Mp88EdaAAACgycbRww TODO for now we treat vibrissa/whisker as a syonym, but these have different follicles. We could introduce subclasses (see also: Pangolin scales) UBERON:0001037 UBERON:0001037 UMLS:C0018494 UMLS:C0018494 VHOG:0001191 VHOG:0001191 coat hair coat hair coat/ hair coat/ hair fur fur hair hair microchaeta microchaeta quill quill setulae setulae this class defines an individual hair uberon uberon vibrissa vibrissa whisker whisker hindgut The caudalmost subdivision of a digestive tract. metenteron primordium primordium 原基 Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. bud future organ placode primordia rudiment Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. bud future organ placode primordia rudiment 原基 原基是连续细胞的群体，而这些细胞在形态学上是不同的，并且已经对应于后来的器官/组织[FBbt，Hartenstein，V。（2004）]。 基板 未来的器官 芽 萌芽 anatomical entity anatomical entity 解剖实体 AAO:0010841 AAO:0010841 AEO:0000000 AEO:0000000 BILA:0000000 BILA:0000000 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. CARO:0000000 CARO:0000000 EHDAA2:0002229 EHDAA2:0002229 FBbt:10000000 FBbt:10000000 FBbt_root:00000000 FBbt_root:00000000 FMA:62955 FMA:62955 HAO:0000000 HAO:0000000 MA:0000001 MA:0000001 NCIT:C12219 TAO:0100000 TAO:0100000 TGMA:0001822 TGMA:0001822 UBERON:0001062 UBERON:0001062 UMLS:C1515976 UMLS:C1515976 WBbt:0000100 XAO:0000000 XAO:0000000 ZFA:0100000 ZFA:0100000 uberon uberon AAO:0010841 AEO:0000000 BILA:0000000 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. CARO:0000000 EHDAA2:0002229 FBbt:10000000 FBbt_root:00000000 FMA:62955 HAO:0000000 MA:0000001 TAO:0100000 TGMA:0001822 UBERON:0001062 UMLS:C1515976 XAO:0000000 ZFA:0100000 uberon 生物实体，既可以是一个生物物种的个体成员，也可以构成一个生物物种一个个体成员的结构组织。 skin of back A zone of skin that is part of a back [Automatically generated definition]. EMAPA:36392 FMA:10462 FMA:22985 MA:0000498 TODO - distinguish between entire skin of region and arbitrary zone of skin on region UBERON:0001068 back skin back zone of skin skin, dorsal region uberon zone of skin of back skin of trunk A zone of skin that is part of a trunk [Automatically generated definition]. EMAPA:37278 FMA:12167 FMA:23093 MA:0000517 NCIT:C12295 TODO - distinguish between entire skin of region and arbitrary zone of skin on region UBERON:0001085 UMLS:C0205031 torso zone of skin trunk skin trunk zone of skin uberon zone of skin of torso zone of skin of trunk urine BTO:0001419 CALOHA:TS-1092 EFO:0001939 EMAPA:36554 ENVO:00002047 Excretion that is the output of a kidney FMA:12274 GAID:1189 MA:0002545 MAT:0000058 MESH:D014556 MIAA:0000058 NCIT:C13283 OpenCyc:Mx4rvVjGppwpEbGdrcN5Y29ycA UBERON:0001088 UMLS:C0042036 galen:Urine kidney excreta from some taxa (e.g. in aves) may not be liquid uberon scrotum BTO:0003098 CALOHA:TS-2341 EMAPA:19296 FMA:18252 GAID:393 In elephants the testes remain in the abdomen In hedgehogs the testes remain in the inguinal canal In humans and some other mammals, the base of the scrotum becomes covered with pubic hair at puberty In marsupials, the scrotum is not homologous to the eutherian scrotum, and development is under the control of X-linked genes, not androgens In marsupials, the scrotum is positioned in the caudal area of the abdomen, in the same position as the pouch in females. It has been suggested that the pouch and marsupial scrotum are sexual homologs, but it is more likely they arise from different primordia in the same morphogenetic field MA:0000409 MESH:D012611 NCIT:C12785 OpenCyc:Mx4rwUC_upwpEbGdrcN5Y29ycA The scrotum of marsupials is not homologous with the scrotum of mammals[ISBN:113945742X] UBERON:0001300 UMLS:C0036471 galen:Scrotum scrotal the external sac of skin that encloses the testes. It is an extension of the abdomen, and in placentals is located between the penis and anus. uberon prepuce of penis A retractable double-layered fold of skin and mucous membrane that covers the glans penis and protects the urinary meatus when the penis is not erect. BTO:0001113 CALOHA:TS-0383 EFO:0001664 EMAPA:18989 EV:0100109 FMA:19639 MA:0000407 OpenCyc:Mx4rvVjlTZwpEbGdrcN5Y29ycA UBERON:0001332 UMLS:C0227952 foreskin foreskin penile prepuce penile prepuce praeputium praeputium prepuce prepuce prepuce of male prepuce of male prepucium prepucium preputium preputium preputium penis preputium penis uberon anal region The anus and surrounding regions. Encompasses both internal and external regions, where present posterior posterior end of organism skin of abdomen A zone of skin that is part of an abdomen [Automatically generated definition]. EFO:0000214 FMA:22988 FMA:23000 MA:0000523 NCIT:C52758 UBERON:0001416 UMLS:C0222166 abdomen skin abdomen zone of skin abdominal skin skin of abdomen proper uberon zone of skin of abdomen skin of limb A zone of skin that is part of a limb [Automatically generated definition]. EMAPA:32726 FMA:23100 MA:0000694 NCIT:C53276 UBERON:0001419 UMLS:C1282135 limb skin limb zone of skin uberon zone of skin of limb skeletal system skeletal system 骨骼系统 Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. Skelettsystem set of all bones and joints skeleton system Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. Skelettsystem set of all bones and joints skeleton system 所有骨骼和关节的集合 由骨骼和关节系统组成的多元、多组织解剖集群的解剖系统。 骨架系统 骨骼系统 bone element bone element 骨骼元素 AAO:0000047 AEO:0000082 Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO] BTO:0000140 CALOHA:TS-0088 EFO:0000298 EHDAA2:0003082 EMAPA:32782 ENVO:00002039 EV:0100140 FMA:30317 FMA:5018 GAID:92 MA:0001459 MAT:0000299 MIAA:0000299 OpenCyc:Mx4rvViDlpwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVkCG5wpEbGdrcN5Y29ycA Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system.[TAO] Skeletal element that is composed of bone tissue. Skeletal element that is composed of bone tissue.[VSAO] TAO:0001514 The 'new animal phylogeny' reveals that many of the groups known to biomineralize sit among close relatives that do not, and it favours an interpretation of convergent or parallel evolution for biomineralization in animals. (...) Whether this 'biomineralization toolkit'of genes reflects a parallel co-option of a common suite of genes or the inheritance of a skeletogenic gene regulatory network from a biomineralizing common ancestor remains an open debate.[debated][VHOG] UBERON:0001474 UMLS:C0262950 VHOG:0001190 VSAO:0000057 XAO:0000169 ZFA:0001514 bone bone bone element bone organ bone organ bones bones galen:Bone relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] uberon AAO:0000047 AEO:0000082 Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO] BTO:0000140 CALOHA:TS-0088 EFO:0000298 EHDAA2:0003082 EMAPA:32782 ENVO:00002039 EV:0100140 FMA:30317 FMA:5018 GAID:92 MA:0001459 MAT:0000299 MIAA:0000299 OpenCyc:Mx4rvViDlpwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVkCG5wpEbGdrcN5Y29ycA Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system.[TAO] Skeletal element that is composed of bone tissue. Skeletal element that is composed of bone tissue.[VSAO] TAO:0001514 The 'new animal phylogeny' reveals that many of the groups known to biomineralize sit among close relatives that do not, and it favours an interpretation of convergent or parallel evolution for biomineralization in animals. (...) Whether this 'biomineralization toolkit'of genes reflects a parallel co-option of a common suite of genes or the inheritance of a skeletogenic gene regulatory network from a biomineralizing common ancestor remains an open debate.[debated][VHOG] UBERON:0001474 UMLS:C0262950 VHOG:0001190 VSAO:0000057 XAO:0000169 ZFA:0001514 bone bone bone element bone element bone organ bone organ bones bones galen:Bone relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO] uberon "新动物发展史"揭示了许多已知的生物矿化群存在于不存在生物矿化的近亲之中，并且它有利于解释动物生物矿化的会聚或平行进化。（...） 这个"生物矿化工具箱"反映的是一组共同基因的平行选择，还是来自一个生物矿化共同祖先的Skeletogenic基因调控网络的遗传，仍然是一个公开的争论。 关系缺失:详细说明结缔组织的亚类(AAO:0000571)[AAO] 又称骨组织，(Latin: os)。 是一种在许多脊椎动物中发现的硬骨内结缔组织。骨是身体器官的主要组织，支持身体结构，保护内部器官，（与肌肉结合）促进运动，并参与细胞形成、钙代谢和矿物质储存[AAO] 由骨组织组成的骨骼元素。 由骨组织组成的骨骼元素。[VSAO] 组织的一部分是钙化的结缔组织，构成骨骼系统的结构元素[TAO] 骨(bone) 骨(bone) 骨(bones) 骨(bones) 骨器官 骨器官 骨骼元素 骨骼元素 muscle of arm A muscle organ that is part of an arm [Automatically generated definition]. EHDAA:8277 EMAPA:36053 MA:0000594 RETIRED_EHDAA2:0000142 See notes on UBERON:0001460 for possible terminological confusion over term 'arm'. MA uses this consistent with uberon (forelimb muscle is subdivided into shoulder, arm and hand) UBERON:0001499 UBERON:0003272 arm muscle arm muscle system arm skeletal muscle arm skeletal muscle tissue muscle of upper arm or lower arm uberon upper arm / lower arm muscle skin of leg A zone of skin that is part of a leg [Automatically generated definition]. EMAPA:18156 EMAPA:18159 EMAPA:37352 FMA:37828 MA:0000674 NCIT:C52749 UBERON:0001511 UMLS:C0222279 leg skin leg zone of skin uberon zone of skin of leg muscle organ muscle organ 肌肉器官 AAO:0011066 EMAPA:32715 EMAPA:37474 EV:0100146 FMA:5022 GAID:131 It seems clear that the metazoan ancestor inherited from its unicellular descendants an actin cytoskeleton and motor-proteins of the myosin superfamily. Within metazoans, these two molecules were arranged into effective contractile units, the muscles. The basic trends for muscle evolution are already expressed in the diploblastic taxa.[well established][VHOG] MA:0000015 OpenCyc:Mx4rv2kf-5wpEbGdrcN5Y29ycA Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. Portion of tissue composed of contractile fibers.[TAO] TAO:0005145 UBERON:0001630 VHOG:0001245 XAO:0000172 ZFA:0005145 galen:Muscle muscle muscular uberon Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. muscle 由各种细长细胞组成的组织器官，善于收缩，从而产生运动和机械功[GO]。 肌肉 blood plasma The liquid component of blood, in which erythrocytes are suspended. blood plasm plasma portion of blood plasma portion of plasma blood vessel blood vessel 血管 A vessel through which blood circulates in the body. AAO:0011004 AEO:0000207 Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG] Any of the vessels through which blood circulates in the body.[AAO] BTO:0001102 CALOHA:TS-0080 EFO:0000817 EHDAA2:0003252 EHDAA:240 EMAPA:32743 EMAPA:35993 FMA:50722 FMA:63183 FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX GAID:169 MA:0000060 MAT:0000393 MESH:D001808 OpenCyc:Mx4rvVjxlpwpEbGdrcN5Y29ycA TAO:0002137 The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG] UBERON:0001981 UMLS:C0005847 VHOG:0001250 XAO:0001011 ZFA:0005314 annelids have blood vessels, but this class is not applicable to annelids. consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus region of vascular tree organ region of vascular tree organ uberon vas sanguineum vas sanguineum vascular element vascular element vascular tree organ region vascular tree organ region A vessel through which blood circulates in the body. AAO:0011004 AEO:0000207 Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG] Any of the vessels through which blood circulates in the body.[AAO] BTO:0001102 CALOHA:TS-0080 EFO:0000817 EHDAA2:0003252 EHDAA:240 EMAPA:32743 EMAPA:35993 FMA:50722 FMA:63183 FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX GAID:169 MA:0000060 MAT:0000393 MESH:D001808 OpenCyc:Mx4rvVjxlpwpEbGdrcN5Y29ycA TAO:0002137 The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG] UBERON:0001981 UMLS:C0005847 VHOG:0001250 XAO:0001011 ZFA:0005314 annelids have blood vessels, but this class is not applicable to annelids. consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus region of vascular tree organ region of vascular tree organ uberon vas sanguineum vas sanguineum vascular element vascular element vascular tree organ region vascular tree organ region FMA:63183血管被归类为"一般解剖学术语"。建议在JAX上从Terry H映射到血管树区域。 环节动物有血管，但该类不适用于环节动物。 考虑采用EMAPA父类血管成分,其包括微血管（例如毛细血管），血管丛 脊索动物和随后的脊椎动物的出现伴随着这种原始线性心脏的快速结构多样化：环状、单向循环、封闭的脉管系统和传导系统。[well established][VHOG] 血液在体内循环通过的任何血管。 [AAO] 血液在体内循环通过的任何血管。 [XAO:0001011_][VHOG] 血液通过血管在身体循环。 血管元件 血管元件 血管树器官区域(region of vascular tree organ) 血管树器官区域(region of vascular tree organ) 血管树器官区域(vascular tree organ region) 血管树器官区域(vascular tree organ region) 血管痉挛 血管痉挛 olfactory epithelium A sensory epithelium inside the nasal cavity that is responsible for detecting odors[WP]. AAO:0010158 BTO:0000108 CALOHA:TS-0703 EFO:0001972 EHDAA2:0001228 EHDAA:4774 EMAPA:17606 FMA:64803 Genes: V1Rs, Trpc2 present in lamprey MA:0001325 MAT:0000445 MOE NCIT:C33203 Sensory lining of the medial wall, roof and anterior aspects of the main olfactory cavity (cavum principale).[AAO] TAO:0000554 UBERON:0001997 UBERON:0004853 UMLS:C0599332 VHOG:0000985 ZFA:0000554 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=1900 main olfactory epithelium nasal cavity olfactory epithelium nasal epithelium nasal sensory epithelium olfactory membrane olfactory sensory epithelium pseudostratified main olfactory epithelium relationship loss: part_of principal cavity (AAO:0000992)[AAO] sensory olfactory epithelium uberon vasculature vasculature 血管系统 An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. BTO:0003718 FMA:69050 TAO:0005249 UBERON:0002049 ZFA:0005249 see also: vascular system. Consider merging? uberon vascular vascular network vascular network An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. BTO:0003718 FMA:69050 TAO:0005249 UBERON:0002049 ZFA:0005249 see also: vascular system. Consider merging? uberon vascular vascular network vascular network 包含有效地运输到生物周围的流体的互相连接的管状多组织结构[ZFA]。例如：肺的血管系统，脸部的血管系统。 另见：血管系统。 考虑合并？ 血管 血管网络 血管网络 embryonic structure embryonic structure 胚胎结构 Anatomical structure that is part of an embryo. developing embryonic structure developing structure embryonale Struktur embryonic anatomical structure embryonic structures Anatomical structure that is part of an embryo. developing embryonic structure developing structure embryonale Struktur embryonic anatomical structure embryonic structures 发育结构 发育胚胎结构 是胚胎一部分的解剖结构。 胚胎结构 胚胎解剖结构 dermis A collagenous layer of the skin subjacent to the epidermis and covering the hypodermis. It contains various types of cells (e.g. fibroblasts, pigment cells, nerve, blood vessels and scales. Le Guellec et al, 2004.[TAO] AAO:0000128 BTO:0000294 CALOHA:TS-2076 Consider adding a layer-of-skin grouping class for all skin layers EFO:0000953 EMAPA:17527 EV:0100154 FMA:70323 GAID:1321 MA:0000152 MAT:0000153 MESH:D020405 MIAA:0000153 TAO:0001119 The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. UBERON:0002067 UMLS:C0011646 VHOG:0000108 When approaching controversies surrounding skin evolution, we need to remember that the skin consists of two layers, an epidermis and a dermis, not a single evolving structure. (...) It is little wonder that controversies about homology exist. If we think of the epidermis, the dermis, and their interactions as an evolving unit, then their specialized products (hair, feathers, and reptilian scales) are broadly homologous.[well established][VHOG] XAO:0000217 ZFA:0001119 corium corium cutis cutis dermal uberon vertebrate dermis vertebrate dermis hypodermis A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO] A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]. BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument. BTO:0001314 CALOHA:TS-2366 FMA:70544 Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. TAO:0001136 UBERON:0002072 UMLS:C0278403 ZFA:0001136 hypoderm hypoderm hypodermal sub-tegumental tissue sub-tegumental tissue subcutaneous subcutaneous tissue subcutaneous tissue subcutaneus subcutis subcutis subtegumental tissue subtegumental tissue superficial fascia superficial fascia tela subcutanea tela subcutanea uberon vertebrate hypodermis vertebrate hypodermis postcranial axial skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. axial skeleton post-cranial axial skeleton skin of body The organ covering the body that consists of the dermis and epidermis. entire integument entire skin integument integumental organ pelt skin skin organ trunk trunk 躯干 AAO:0010339 BILA:0000116 BTO:0001493 CALOHA:TS-1071 EFO:0000966 EMAPA:31857 FMA:7181 MA:0000004 MAT:0000296 MIAA:0000296 OpenCyc:Mx4rvVkJjpwpEbGdrcN5Y29ycA Organism subdivision that is the part of the body posterior to the head and anterior to the tail.[AAO] Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. Organism subdivision which is the part of the body posterior to the head and anterior to the tail.[TAO] Rumpf Rumpf TAO:0001115 UBERON:0002100 UMLS:C0460005 XAO:0000054 XAO:0003025 ZFA:0001115 galen:Trunk thoracolumbar region thoracolumbar region torso torso trunk region trunk region uberon AAO:0010339 BILA:0000116 BTO:0001493 CALOHA:TS-1071 EFO:0000966 EMAPA:31857 FMA:7181 MA:0000004 MAT:0000296 MIAA:0000296 OpenCyc:Mx4rvVkJjpwpEbGdrcN5Y29ycA Organism subdivision that is the part of the body posterior to the head and anterior to the tail.[AAO] Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. Organism subdivision which is the part of the body posterior to the head and anterior to the tail.[TAO] Rumpf Rumpf TAO:0001115 UBERON:0002100 UMLS:C0460005 XAO:0000054 XAO:0003025 ZFA:0001115 galen:Trunk thoracolumbar region thoracolumbar region torso torso trunk region trunk region uberon 主干区域 主干区域 在颈部后方（或头部，当颈部区域不存在时）和在尾部区域前方的身体部分的有机体细分。当出现时包括骶骨。 朗夫 生物体在头部后面和尾部前面的部分。[AAO] 生物体的部分，它是身体头部后面和尾部前面的部分。[TAO] 胸腰区域 胸腰区域 躯干 躯干 hemolymphoid system hemolymphoid system 血淋巴系统 Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. haemolymphoid system hematolymphoid system lymphomyeloid complex Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. haemolymphoid system hematolymphoid system lymphomyeloid complex 淋巴细胞复合体 由造血系统和淋巴系统，或其类似物组成的解剖集群。 血淋巴系统 血淋巴系统(haemolymphoid system) integument Hautsystem@de The dermis, epidermis and hypodermis. dermal system dermis plus epidermis plus hypodermis dermoid system integumentum commune skin skin and subcutaneous tissue skin plus hypodermis tegument the integument vertebrate integument musculoskeletal system musculoskeletal system 肌肉骨骼系统 Anatomical system that consists of the muscular and skeletal systems. musculo-skeletal system Anatomical system that consists of the muscular and skeletal systems. musculo-skeletal system 由肌肉和骨骼系统组成的解剖系统。 肌肉骨骼系统 synovial joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA] articulatio synoviale diarthrodial joints diarthroses diarthrosis diarthrosis joint umbilical cord BTO:0001415 BTO:0001415 CALOHA:TS-1078 CALOHA:TS-1078 EFO:0001415 EFO:0001415 EHDAA2:0000312 EHDAA2:0000312 EHDAA:158 EHDAA:158 EMAPA:26115 EMAPA:26115 EV:0100127 EV:0100127 FMA:85541 FMA:85541 GAID:517 GAID:517 MAT:0000280 MAT:0000280 MESH:A16.254.789 MESH:A16.254.789 MIAA:0000280 MIAA:0000280 NCIT:C34320 OpenCyc:Mx4rvyewDJwpEbGdrcN5Y29ycA OpenCyc:Mx4rvyewDJwpEbGdrcN5Y29ycA See notes for connecting stalk The connecting cord from the developing embryo or fetus to the placenta. During prenatal development, the umbilical cord comes from the same zygote as the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta.property_value, external_definition the umbilical arteries return the deoxygenated, nutrient-depleted blood[WP]. The connecting cord from the developing embryo to the placenta. UBERON:0002331 UBERON:0002331 UMLS:C0041633 UMLS:C0041633 birth cord birth cord chorda umbilicalis chorda umbilicalis connecting stalk connecting stalk funiculus umbilicalis funiculus umbilicalis funiculus umbilicalis funiculus umbilicalis uberon uberon umbilical yolk stalk yolk stalk prostate gland prostate gland 前列腺 BTO:0001129 BTO:0001129 CALOHA:TS-0828 CALOHA:TS-0828 EFO:0000858 EFO:0000858 EMAPA:19287 EMAPA:19287 EV:0100104 EV:0100104 FMA:9600 FMA:9600 GAID:392 GAID:392 MA:0000404 MA:0000404 MAT:0000078 MAT:0000078 MESH:D011467 MESH:D011467 MIAA:0000078 MIAA:0000078 NCIT:C12410 OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA TODO - FMA treats the gland as part of the prostate - see also FMA:74119. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. UBERON:0002367 UBERON:0002367 UMLS:C0033572 UMLS:C0033572 VHOG:0001261 VHOG:0001261 galen:ProstateGland galen:ProstateGland male prostate male prostate prostata prostata prostate prostate prostatic uberon uberon BTO:0001129 CALOHA:TS-0828 EFO:0000858 EMAPA:19287 EV:0100104 FMA:9600 GAID:392 MA:0000404 MAT:0000078 MESH:D011467 MIAA:0000078 OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA TODO - FMA treats the gland as part of the prostate - see also FMA:74119. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. UBERON:0002367 UMLS:C0033572 VHOG:0001261 galen:ProstateGland male prostate prostata prostate prostatic uberon 前列腺 前列腺(prostata) 前列腺(prostate) 前列腺是位于哺乳动物男性尿道底部附近的部分肌肉、部分腺体，并分泌碱性粘液，这些粘液是射精液的主要成分。 待办事项-FMA将腺体视为前列腺的一部分 - 另见FMA：74119。 男性前列腺 bone marrow bone marrow 骨髓 AAO:0011007 AAO:0011007 BTO:0000141 BTO:0000141 BTO:0000829 BTO:0000829 CALOHA:TS-0087 CALOHA:TS-0087 EFO:0000868 EFO:0000868 EMAPA:32760 EMAPA:32760 EV:0100046 EV:0100046 FMA:9608 FMA:9608 GAID:1287 GAID:1287 In adults, marrow in large bones produces new blood cells[Wikipedia:Bone_marrow] MA:0000134 MA:0000134 MAT:0000084 MAT:0000084 MESH:D001853 MESH:D001853 MIAA:0000084 MIAA:0000084 NCIT:C12431 OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG] UBERON:0002371 UBERON:0002371 UMLS:C0005953 UMLS:C0005953 VHOG:0001218 VHOG:0001218 XAO:0000123 XAO:0000123 consider placement of NCIT:C53466 medullary bone galen:BoneMarrow galen:BoneMarrow medulla of bone medulla of bone medulla ossea medulla ossea medulla ossium medulla ossium medullary bone the soft tissue that fills the cavities of bones uberon uberon AAO:0011007 BTO:0000141 BTO:0000829 CALOHA:TS-0087 EFO:0000868 EMAPA:32760 EV:0100046 FMA:9608 GAID:1287 In adults, marrow in large bones produces new blood cells[Wikipedia:Bone_marrow] MA:0000134 MAT:0000084 MESH:D001853 MIAA:0000084 OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG] UBERON:0002371 UMLS:C0005953 VHOG:0001218 XAO:0000123 galen:BoneMarrow medulla of bone medulla of bone medulla ossea medulla ossea medulla ossium medulla ossium the soft tissue that fills the cavities of bones uberon 充满骨骼腔的软组织 在成人中，大骨头中的骨髓产生新的血细胞。[well established][VHOG] 待办事项-创造骨髓/头肾的超级类别。 两者都是造血系统中组织的一部分。 也可以考虑加入作为骨器官区域的子类别来保持与FMA的一致性。 另见：睾丸间质和壁囊器 骨髓(medulla of bone) 骨髓(medulla of bone) 骨髓(medulla ossium) 骨髓(medulla ossium) 骨髓是所有脊椎动物而不是鱼类的造血器官，在这些器官中，肾脏中发生造血。[Well well] [VHOG] 髓质骨 髓质骨 connective tissue connective tissue 结缔组织 AAO:0000098 BTO:0000421 Bindegewebe Bindegewebe CALOHA:TS-2009 EFO:0000952 EMAPA:35251 FMA:9640 GAID:100 MA also has set of connective tissues MA:0000011 MAT:0000301 MESH:D003238 MIAA:0000301 One of the four types of tissue in traditional classifications. It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category, such as involvement in structure and support, derived from mesoderm, and characterized largely by the traits of non-living tissue.[AAO] OpenCyc:Mx4rv-aBgZwpEbGdrcN5Y29ycA Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.[TAO] TAO:0001641 Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance.[VSAO] UBERON:0002384 UMLS:C0009780 VSAO:0000017 XAO:0001017 ZFA:0001632 galen:ConnectiveTissue portion of connective tissue portion of connective tissue textus connectivus textus connectivus uberon AAO:0000098 BTO:0000421 Bindegewebe Bindegewebe CALOHA:TS-2009 EFO:0000952 EMAPA:35251 FMA:9640 GAID:100 MA also has set of connective tissues MA:0000011 MAT:0000301 MESH:D003238 MIAA:0000301 One of the four types of tissue in traditional classifications. It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category, such as involvement in structure and support, derived from mesoderm, and characterized largely by the traits of non-living tissue.[AAO] OpenCyc:Mx4rv-aBgZwpEbGdrcN5Y29ycA Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.[TAO] TAO:0001641 Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance.[VSAO] UBERON:0002384 UMLS:C0009780 VSAO:0000017 XAO:0001017 ZFA:0001632 galen:ConnectiveTissue portion of connective tissue portion of connective tissue textus connectivus textus connectivus uberon MA也有一套结缔组织。 传统分类中的四种组织中的一种。这主要是排除的范畴，而不是定义精确的范畴，但这一范畴中的所有或大多数组织都有某些共同的特征，如结构和支持的参与，源自中胚层，主要以非活组织的特征为特征。[AAO] 具有沉积非极化的细胞外基质（包括结缔组织纤维和基质）的细胞的组织。 具有沉积非极化细胞外基质（包括结缔组织纤维和基质物质）的细胞的组织。[VSAO] 组织的一部分，由中胚层来源的细胞和由蛋白质纤维和碳水化合物组成的细胞间基质组成，支持、包裹和结合其它组织。[TAO] 结缔组织 结缔组织 结缔组织(textus connectivus) 部分结缔组织 部分结缔组织 muscle tissue muscle tissue 肌肉组织 AAO:0000306 AEO:0000122 CALOHA:TS-0642 EHDAA2:0003122 EMAPA:32715 FMA:9641 MA:0002437 MESH:D009132 Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO] UBERON:0002385 UMLS:C2328219 Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach. galen:MuscleTissue muscular tissue muscular tissue portion of muscle tissue portion of muscle tissue textus muscularis textus muscularis uberon AAO:0000306 AEO:0000122 CALOHA:TS-0642 EHDAA2:0003122 EMAPA:32715 FMA:9641 MA:0002437 MESH:D009132 Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO] UBERON:0002385 UMLS:C2328219 Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach. galen:MuscleTissue muscular tissue muscular tissue portion of muscle tissue portion of muscle tissue textus muscularis textus muscularis uberon 传统分类中的四种组织中的一种。包含具有收缩丝的细胞的组织，这些收缩丝彼此移动并改变细胞的大小。肌肉组织也分为三种不同的类别。[AAO] 肌组织 肌组织 肌肉组织 肌肉组织 肌肉组织是由肌动蛋白和肌球蛋白纤维组成的收缩组织[GO]。 肌肉组织的一部分 肌肉组织的一部分 脊椎动物肌肉根据其结构和功能特性分为三种主要的肌肉类型：骨骼，心脏和平滑肌。在Dmel中，对应物是躯体，心脏/心脏和内脏。这里我们采取一种基于细胞类型的方法。 hematopoietic system hematopoietic system 造血系统 Anatomical system that is involved in the production of hematopoietic cells. Blutbildungssystem haematological system haematopoietic system haemopoietic system hematological system hematolymphoid system hemopoietic system organa haemopoietica Anatomical system that is involved in the production of hematopoietic cells. Blutbildungssystem haematological system haematopoietic system haemopoietic system hematological system hematolymphoid system hemopoietic system organa haemopoietica 参与造血细胞生成的解剖系统。 血液系统 血液系统(haematological system) 血淋巴系统 造血系统 造血系统(haematopoietic system) 造血系统(hemopoietic system) 造血系统(organa haemopoietica) immune system immune system 免疫系统 Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. 通过产生免疫应答来保护身体免受外来物质、细胞和组织的影响的解剖系统，尤其包括胸腺、脾脏、淋巴组织、包括B细胞和T细胞的淋巴细胞以及抗体。 integumental system integumental system 体被系统 Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. body surface dermal system external covering of organism integumentary system integumentum commune organism surface surface Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. body surface dermal system external covering of organism integumentary system integumentum commune organism surface surface 外皮系统 生物体的外部覆盖 生物体表面 真皮系统 表面 身体表面 连接的解剖系统，形成动物与环境之间的屏障。在脊椎动物中，包皮系统由表皮、真皮加上相关的腺体和附属物如头发和鳞屑组成。在无脊椎动物，包皮系统可能包括角质层。 abdominal segment of trunk The abdominal segment of the torso. abdomen/pelvis/perineum lower body lower trunk lumbar region bone tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. bone calcium tissue mineralized bone tissue osseous tissue osteogenic tissue portion of bone tissue gland gland 腺(gland) AAO:0000212 AAO:0000212 AEO:0000096 AEO:0000096 BTO:0000522 BTO:0000522 Druese Druese EFO:0000797 EFO:0000797 EHDAA2:0003096 EHDAA2:0003096 EHDAA:2161 EHDAA:2161 EHDAA:4475 EHDAA:4475 EHDAA:6522 EHDAA:6522 EMAPA:18425 EMAPA:18425 FBbt:00100317 FBbt:00100317 FMA:7146 FMA:7146 FMA:86294 FMA:86294 HAO:0000375 HAO:0000375 MA:0003038 MA:0003038 MAT:0000021 MAT:0000021 MIAA:0000021 MIAA:0000021 NCIT:C13319 OpenCyc:Mx4rwP3vyJwpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3vyJwpEbGdrcN5Y29ycA UBERON:0002530 UBERON:0002530 UBERON:MIAA_0000021 UBERON:MIAA_0000021 UMLS:C1285092 UMLS:C1285092 WikipediaCategory:Glands WikipediaCategory:Glands an organ that functions as a secretory or excretory organ galen:Gland galen:Gland glandula glandula glandular glandular organ glandular organ uberon uberon AAO:0000212 AEO:0000096 BTO:0000522 Druese Druese EFO:0000797 EHDAA2:0003096 EHDAA:2161 EHDAA:4475 EHDAA:6522 EMAPA:18425 FBbt:00100317 FMA:7146 FMA:86294 HAO:0000375 MA:0003038 MAT:0000021 MIAA:0000021 OpenCyc:Mx4rwP3vyJwpEbGdrcN5Y29ycA UBERON:0002530 UBERON:MIAA_0000021 UMLS:C1285092 WikipediaCategory:Glands an organ that functions as a secretory or excretory organ galen:Gland glandula glandula glandular glandular organ glandular organ uberon 动物腺 动物腺 腺(glandula) 腺(glandula) 腺器官 腺器官 腺状的 起分泌或排泄器官作用的器官 epiblast (generic) epiblast (generic) 外胚层（通用） In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] blastocyst ectoblast epiblast epiblastus primitive ectoderm In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] blastocyst ectoblast epiblast epiblastus primitive ectoderm 原始外胚层 在羊膜动物胚胎学中，外胚层是来源于哺乳动物内细胞团或鸟类和爬行动物胚盘的组织类型。它位于下胚层的上方。在哺乳动物胚胎发生中，外胚层的柱状细胞与滋养层毗邻，而下胚层的立方细胞更接近胚泡。外胚层虽然被称为初级外胚层，但在称为原肠胚形成的过程中分化形成三胚层的所有三层结构[WP]。原肠胚形成期间形成的胚层的两层外层，对应于原肠胚形成期间的原始外胚层和原肠胚形成后的明确的外胚层[ZFA] 外胚叶 外胚层(ectoblast) 外胚层(epiblast) 胚泡 presomitic mesoderm PSM Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. presumptive somite mesoderm segmental plate somitogenic mesoderm somitomeric mesoderm unsegmented mesenchyme unsegmented paraxial mesoderm blood island blood island 血岛 Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. VBI blood islands caudal hematopoietic tissue posterior ICM posterior blood island ventral blood island ventral lateral plate mesoderm Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. VBI blood islands caudal hematopoietic tissue posterior ICM posterior blood island ventral blood island ventral lateral plate mesoderm 后ICM 后血岛 尾部造血组织 腹侧板中胚层 腹血岛 血岛 血岛是发育中的胚胎中的结构，产生循环系统的许多不同部分。它们主要来源于成血管细胞形成的丛。在它们内部，通过将合胞体中央部分液化成血浆产生空泡。这样形成的血管腔可能是细胞内的。外周的扁平细胞形成内皮。有核红血球体由附着在腔内壁原始的血管母细胞的小块肿块发展而来，或者直接从平坦的内皮细胞发展而来。在任何一种情况下，由此形成的合体块体从血管突出并附着在血管上。这样的肿块被称为血岛，血红蛋白在其内部逐渐积累。之后，表面上的细胞聚集起来，形成了桑葚状的外形。然后红细胞散开，在血浆中被带走。这种游离血细胞不断分裂。已经在大面积静脉和动脉的血管以及背主动脉中看见血岛，[WP，unvetted]。 intermediate mesoderm IM The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. intermediate mesenchyme intermediate plate intermediate plate mesoderm mesenchyma intermedium paraxial mesoderm The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO] mesoderma paraxiale paraxial mesenchyme somitic mesoderm lateral plate mesoderm lateral plate mesoderm 侧板中胚层 LPM Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. lateral mesoderm lateral plate lateral plate mesenchyme mesoderma laminae lateralis LPM Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. lateral mesoderm lateral plate lateral plate mesenchyme mesoderma laminae lateralis 中胚层外侧薄层 位于胚胎外围的胚胎三个主要胚层的中间部分与胚外中胚层相连，分裂成包围胚胎内胚体的两层，并产生体壁结构[ MP。 外侧中胚层 外侧板 外侧板间充质 heart primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. cardiac field fused heart primordium sclerotome Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. sclerotomes sclerotomus female organism Gonochoristic organism that can produce female gametes. female female human body male organism male organism 雄性生物 Gonochoristic organism that can produce male gametes. male male human body Gonochoristic organism that can produce male gametes. male male human body 男性人体 能产生雄性配子的雌雄异体生物。 雄性 surface structure surface structure 表面结构 AAO:0010337 AEO_RETIRED:0000010 Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. EHDAA2_RETIRED:0003010 Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA] TAO:0000292 UBERON:0003102 VSAO:0000001 XAO:0003028 ZFA:0000292 anatomical surface feature anatomical surface feature consider obsoleting. See issue/1305 galen:SurfaceRegion surface feature surface feature surface region surface region surface structures surface structures uberon AAO:0010337 AEO_RETIRED:0000010 Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. EHDAA2_RETIRED:0003010 Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA] TAO:0000292 UBERON:0003102 VSAO:0000001 XAO:0003028 ZFA:0000292 anatomical surface feature anatomical surface feature consider obsoleting. See issue/1305 galen:SurfaceRegion surface feature surface feature surface region surface region surface structures surface structures uberon 与外部上皮层重叠并与生物体周围空间相邻的解剖结构。 生物体的细分，即体表解剖结构的集合。[ZFA] 考虑过时。 见问题/ 1305 表面区域 表面区域 表面特征 表面特征 表面结构 表面结构 解剖学表面特征 解剖学表面特征 compound organ compound organ 复合器官 AAO:0010015 AEO:0000024 Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. BILA:0000024 CARO:0000024 EHDAA2:0003024 HAO:0000024 TADS:0000598 TAO:0000496 TGMA:0001837 UBERON:0003103 VHOG:0001723 XAO:0003041 ZFA:0000496 organ organ this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs uberon AAO:0010015 AEO:0000024 Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. BILA:0000024 CARO:0000024 EHDAA2:0003024 HAO:0000024 TADS:0000598 TAO:0000496 TGMA:0001837 UBERON:0003103 VHOG:0001723 XAO:0003041 ZFA:0000496 organ organ this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs uberon 具有至少两种不同类型的两个或更多个多组织结构，并且通过特定的形态形成过程，形成了一个单一的独立结构单元，由不同类型的其他不同解剖结构的真实边界划分 器官 器官 这个类是为了与CARO保持一致而引入的。 然而，在这个本体中，我们通常将器官直接归类于“器官” 而不是细分为复合和简单的器官 mesenchyme mesenchyme 间充质 Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]. mesenchyma mesenchymal tissue mesenchyme tissue portion of mesenchymal tissue portion of mesenchyme tissue Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]. mesenchyma mesenchymal tissue mesenchyme tissue portion of mesenchymal tissue portion of mesenchyme tissue 由松散组织的未分化的中胚层细胞构成的组织部分产生结缔组织、血液、淋巴管、骨和软骨等结构[XAO]。一种网状细胞排列，比上皮细小[ZFA]。胚胎中胚层的一部分，由松散的、未分化的细胞以凝胶状的基质形成，而结缔组织，骨，软骨以及循环系统和淋巴系统由凝胶状基质发展而来[BTO]。 部分间充质组织 部分间质组织 间质 间质组织(mesenchymal tissue) 间质组织(mesenchyme tissue) reproductive organ reproductive organ 生殖器官 An organ involved in reproduction EMAPA:17381 GO uses genitalia for the singular organ MA:0001752 MESH:D005835 OpenCyc:Mx4rwO39aJwpEbGdrcN5Y29ycA TGMA:0000591 UBERON:0003133 UMLS:C0017420 WBbt:0008422 genital organ genital organ genitalia genitalia reproductive system organ reproductive system organ sex organ sex organ uberon An organ involved in reproduction EMAPA:17381 GO uses genitalia for the singular organ MA:0001752 MESH:D005835 OpenCyc:Mx4rwO39aJwpEbGdrcN5Y29ycA TGMA:0000591 UBERON:0003133 UMLS:C0017420 WBbt:0008422 genital organ genital organ genitalia genitalia reproductive system organ reproductive system organ sex organ sex organ uberon GO使用生殖器作为单一器官。 参与生殖的器官 性器官 性器官 生殖器 生殖器 生殖器官 生殖器官 生殖系统器官 生殖系统器官 female reproductive organ A female organ involved in reproduction female organism reproductive organ female organism reproductive structure female organism reproductive system organ female organism sex organ female reproductive gland/organ female reproductive system organ female sex organ reproductive organ of female organism reproductive structure of female organism reproductive system organ of female organism sex organ of female organism male reproductive organ male reproductive organ 男性生殖器官 A male organ involved in reproduction male organism reproductive organ male organism reproductive structure male organism reproductive system organ male organism sex organ male reproductive gland/organ male reproductive system organ male sex organ reproductive organ of male organism reproductive structure of male organism reproductive system organ of male organism sex organ of male organism A male organ involved in reproduction male organism reproductive organ male organism reproductive structure male organism reproductive system organ male organism sex organ male reproductive gland/organ male reproductive system organ male sex organ reproductive organ of male organism reproductive structure of male organism reproductive system organ of male organism sex organ of male organism 涉及生殖的男性器官 雄性性器官 雄性生殖体生殖器官 雄性生殖系统器官 雄性生殖腺/器官 雄性生物体性器官(male organism sex organ) 雄性生物体性器官(sex organ of male organism) 雄性生物体生殖器官 雄性生物体生殖系统器官(male organism reproductive system organ) 雄性生物体生殖系统器官(reproductive system organ of male organism) 雄性生物体生殖结构(male organism reproductive structure) 雄性生物体生殖结构(reproductive structure of male organism) epithelium of mucosa A layer of epithelial cells on the surface of the mucosa. BTO:0003752 UBERON:0003350 lamina epithelialis mucosa lamina epithelialis mucosae lies on top of lamina propria uberon hindlimb skin A zone of skin that is part of a hindlimb [Automatically generated definition]. EMAPA:32620 FMA:23102 MA:0000665 NCIT:C12297 TODO - check free limb vs pelvic complex UBERON:0003532 UMLS:C0222268 hind limb skin lower limb skin skin of hind limb skin of hindlimb skin of lower extremity skin of lower limb uberon limb muscle Any muscle organ that is part of a limb [Automatically generated definition]. EMAPA:32700 MA:0000692 UBERON:0003661 limb muscle organ limb skeletal muscle muscle organ of limb uberon forelimb muscle AAO:0000204 Any muscle organ that is part of a forelimb. BTO:0000479 EMAPA:36049 FMA and MA class actually refer to muscles of entire pectoral complex FMA:37348 UBERON:0003662 UBERON:0005634 arm muscle system fore limb muscle organ forelimb muscle organ free upper limb muscle muscle of free upper limb muscle of upper limb musculature of arm musculature of the arm uberon upper limb skeletal muscle wing muscle neural tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. nerve tissue nervous tissue portion of neural tissue abdominal segment skin A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. EMAPA:37063 FMA:264898 MA:0000530 UBERON:0003836 abdominal segment of trunk skin skin of abdominal segment of trunk uberon epithelial tube epithelial tube 上皮管 AEO:0000114 EHDAA2:0003114 Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. FBbt:00007474 UBERON:0003914 contrast with a multi-tissue tube, which has as parts both epithelium, connective tissue, possibly muscle layers epithelial or endothelial tube epithelial or endothelial tube uberon AEO:0000114 EHDAA2:0003114 Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. FBbt:00007474 UBERON:0003914 contrast with a multi-tissue tube, which has as parts both epithelium, connective tissue, possibly muscle layers epithelial or endothelial tube epithelial or endothelial tube uberon 上皮或内皮管 上皮或内皮管 上皮管将气体、液体和细胞从一个地方输送到另一个地方，并形成许多器官和组织的基本结构，具有与秀丽隐杆线虫的单细胞排泄器官乃至哺乳动物肾和昆虫的分枝树气管系统不同的管状和组织结构。 与多层组织管相比，其有上皮细胞，结缔组织，可能有肌肉层。 reproductive gland sex gland sex gland 生殖腺 Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. MA:0001751 MA:0001751 UBERON:0003937 UBERON:0003937 genitalia gland genitalia gland gland of genitalia gland of genitalia gland of reproductive system gland of reproductive system reproductive gland reproductive gland reproductive system gland reproductive system gland sex gland uberon uberon Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. MA:0001751 UBERON:0003937 genitalia gland gland of genitalia gland of reproductive system reproductive gland reproductive system gland uberon 任何有组织的细胞集合，作为分泌或排泄器官，与生殖有关。 生殖器腺(genitalia gland) 生殖器腺(gland of genitalia) 生殖系统腺体(gland of reproductive system) 生殖系统腺体(reproductive system gland) 生殖腺 dermatome A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. cutis plate dermatomal mesenchyme epimere mesoderm mesenchyma dermatomiale external male genitalia The external masculine genital organs, including the penis and scrotum external male genital organ male external genitalia organa genitalia masculina externa anatomical conduit anatomical conduit 解剖导管 AEO:0000080 Any tube, opening or passage that connects two distinct anatomical spaces. EHDAA2:0003080 FMA has both conduit and conduit space. In EHDAA2 this is a surface feature FMA:242873 UBERON:0004111 foramen foramen foramina foramina opening opening ostia ostia ostium ostium uberon AEO:0000080 Any tube, opening or passage that connects two distinct anatomical spaces. EHDAA2:0003080 FMA has both conduit and conduit space. In EHDAA2 this is a surface feature FMA:242873 UBERON:0004111 foramen foramen foramina foramina opening opening ostia ostia ostium ostium uberon 任何连接两个不同解剖空间的管，开口或通道。 口(ostia) 口(ostia) 口(ostium) 口(ostium) 在EHDAA2中，这是表面特征。 孔 孔 开口 开口 椎间孔 椎间孔 endoderm-derived structure endoderm-derived structure 内胚层衍生结构 An anatomical structure that develops (entirely or partially) from the endoderm. Grouping term for query purposes UBERON:0004119 UBERON:0004119 uberon uberon An anatomical structure that develops (entirely or partially) from the endoderm. Grouping term for query purposes UBERON:0004119 uberon 从内胚层（全部或部分）发展的解剖结构。 用于查询目的分组术语 mesoderm-derived structure mesoderm-derived structure 中胚层衍生结构 An anatomical structure that develops (entirely or partially) from the mesoderm. FBbt:00025998 FBbt:00025998 Grouping term for query purposes UBERON:0004120 UBERON:0004120 mesodermal derivative mesodermal derivative uberon uberon An anatomical structure that develops (entirely or partially) from the mesoderm. FBbt:00025998 Grouping term for query purposes UBERON:0004120 mesodermal derivative uberon 中胚层衍生物 从中胚层（全部或部分）发展的解剖结构。 用于查询目的分组术语 ectoderm-derived structure ectoderm-derived structure 外胚层衍生结构 An anatomical structure that develops (entirely or partially) from the ectoderm. FBbt:00025990 FBbt:00025990 Grouping term for query purposes UBERON:0004121 UBERON:0004121 ectodermal deriviative ectodermal deriviative uberon uberon An anatomical structure that develops (entirely or partially) from the ectoderm. FBbt:00025990 Grouping term for query purposes UBERON:0004121 ectodermal deriviative uberon 从外胚层（全部或部分）发展的解剖结构。 外胚层衍生物 用于查询目的分组术语 cardiogenic plate The first recognizable structure derived from the heart field cardiac crescent cardiogenic crescent heart rudiment myocardial plate primary heart field A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. FHF PHF first heart field heart field primary heart field heart tube heart tube 心脏管 An epithelial tube that will give rise to the mature heart. embryonic heart tube endocardial heart tube endocardial tube An epithelial tube that will give rise to the mature heart. embryonic heart tube endocardial heart tube endocardial tube 上皮管会产生成熟的心脏。 心内膜心管 心内膜管 胚胎心脏管 cardiac chamber cardiac chamber 心腔 A cardiac chamber surrounds an enclosed cavity within the heart chamber of heart heart chamber A cardiac chamber surrounds an enclosed cavity within the heart chamber of heart heart chamber 一个心脏腔包围着心脏内的一个封闭腔 心腔(chamber of heart) 心腔(heart chamber) external genitalia external genitalia 外生殖器 The external genitalia are the outer sex organs, such as the penis or vulva in mammals external genitalia external reproductive organ external sex organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals external genitalia external reproductive organ external sex organ 外生殖器 外生殖器是外生殖器官，如哺乳动物的阴茎或外阴 外部性器官 外部生殖器官 skeleton skeleton 骨骼 Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. set of all bones set of bones of body Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. set of all bones set of bones of body 一套身体骨头 所有骨头的集合 由所有骨骼元素（例如，骨头、软骨和牙齿）组成的解剖集群。 dermomyotome The bilaminar epithelium formed from the myotome and dermatome. dermamyotome dermomyotomes heart rudiment A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. heart cone rudimentary heart anatomical projection A projection or outgrowth of tissue from a larger body or organ. AAO:0010278 Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, or tissue.[AAO] Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[TAO] Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[VSAO] FMA:67601 HAO:0000822 NCIT:C61549 TAO:0001834 UBERON:0004529 VSAO:0000180 XAO:0004020 anatomical process anatomical protrusion flange flanges galen:Ridge lamella lamellae lamina laminae organ process papilla process process of organ processes processus projection projection projections protrusion ridge ridges shelf shelves should be declared disjoint from organ, but in some ontologies (e.g. ZFA), structures such as neural spines are classified as bones (and hence organs) spine uberon cardiovascular system cardiovascular system 心血管系统 Anatomical system that has as its parts the heart and blood vessels. CV system Herz und Gefaesssystem Anatomical system that has as its parts the heart and blood vessels. CV system Herz und Gefaesssystem CV系统 以心脏和血管为组成部分的解剖系统。 blood vasculature blood vasculature 血管系统 A vascular network consisting of blood vessels. blood system blood vascular network blood vessel system blood vessels set of blood vessels A vascular network consisting of blood vessels. blood system blood vascular network blood vessel system blood vessels set of blood vessels 一套血管 由血管组成的血管网 血液系统 血管 血管系统 血管网络(blood vascular network) conceptus conceptus 孕体 The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. embryo plus adnexa The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. embryo plus adnexa 胚胎及其附属物（附属物或附属部分）或相关的膜（即受孕的产物）这个概念包括由合子发育而来的所有胚胎和胚外胚胎的结构。它包括胚胎以及胎盘的胚胎部分及其相关的膜-羊膜、绒毛膜（孕囊）和卵黄囊[WP]。 胚胎附属物 skeletal tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from MA:0003047 UBERON:0004755 VSAO:0000015 XAO:0004038 ZFA:0005619 uberon skeletal element skeletal element 骨骼元素 AAO:0011129 Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] TAO:0001890 UBERON:0004765 VSAO:0000128 XAO:0004012 ZFA:0005494 galen:SkeletalStructure uberon AAO:0011129 Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] TAO:0001890 UBERON:0004765 VSAO:0000128 XAO:0004012 ZFA:0005494 galen:SkeletalStructure uberon 典型地参与机械支持的器官实体，其在不同阶段可能具有不同的骨骼组织组成。[VSAO] 在不同阶段可能有不同组织成分的器官实体，通常参与机械支持。[TAO] 由骨骼组织组成的器官。包括整个骨头、融合的骨头、软骨元素，牙齿，真皮细齿。 articular system articular system 关节系统 Anatomical system that consists of all the joints of the body. joint system set of all joints set of all joints of body set of joints of body Anatomical system that consists of all the joints of the body. joint system set of all joints set of all joints of body set of joints of body 一组身体关节 关节系统 所有关节的集合 由身体的所有关节组成的解剖系统。 身体的所有关节的集合 respiratory tract epithelium BTO:0000419 CALOHA:TS-0023 EMAPA:32827 MA:0001480 UBERON:0004802 VHOG:0000981 airway epithelium epithelial tissue of respiratory tract epithelium of respiratory tract respiratory epithelium respiratory tract epithelial tissue the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi uberon respiratory system epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. CALOHA:TS-0023 EMAPA:32826 MA:0001823 UBERON:0004807 VHOG:0000981 apparatus respiratorius epithelial tissue apparatus respiratorius epithelium epithelial tissue of apparatus respiratorius epithelial tissue of respiratory system epithelium of apparatus respiratorius epithelium of respiratory system respiratory system epithelial tissue uberon upper respiratory tract epithelium An epithelium that is part of a upper respiratory tract [Automatically generated definition]. EMAPA:35894 MA:0001912 UBERON:0004814 epithelial tissue of upper respiratory tract epithelium of upper respiratory tract uberon upper respiratory tract epithelial tissue splanchnic layer of lateral plate mesoderm splanchnic layer of lateral plate mesoderm 侧板中胚层内脏层 Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. inner layer of lateral plate mesoderm splanchnic mesoderm visceral mesoderm Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. inner layer of lateral plate mesoderm splanchnic mesoderm visceral mesoderm 侧板中胚层的内层 内脏中胚层(splanchnic mesoderm) 内脏中胚层(visceral mesoderm) 形成循环系统和未来肠壁的侧板中胚层-覆盖内胚层[WP]。 somatopleure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. urogenital fold One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]. urethral fold urogenital fold urogenital ridge articulation articulation 关节 Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. FBbt:00005811 UBERON:0004905 joint joint uberon Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. FBbt:00005811 UBERON:0004905 joint uberon 关节 连接两个或更多相邻骨骼元素或硬化身体部位的解剖集群。 subdivision of digestive tract subdivision of digestive tract 消化道分支 A proximal-distal subdivision of the digestive tract. FBbt:00100315 FMA:71131 UBERON:0004921 alimentary system subdivision alimentary system subdivision intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct. intestinal tract intestinal tract segment of intestinal tract segment of intestinal tract subdivision of alimentary system subdivision of alimentary system uberon A proximal-distal subdivision of the digestive tract. FBbt:00100315 FMA:71131 UBERON:0004921 alimentary system subdivision alimentary system subdivision intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct. intestinal tract intestinal tract segment of intestinal tract segment of intestinal tract subdivision of alimentary system subdivision of alimentary system uberon 旨在表示胚胎和成人结构。 注意这里的FMA分组是不完全正确的。 消化系统细分(alimentary system subdivision) 消化系统细分(alimentary system subdivision) 消化系统细分(subdivision of alimentary system) 消化系统细分(subdivision of alimentary system) 消化道的近端-远端细分。 肠道 肠道 肠道段 肠道段 organ component layer organ component layer 器官组件层 A part of a wall of an organ that forms a layer. FMA:82485 UBERON:0004923 uberon A part of a wall of an organ that forms a layer. FMA:82485 UBERON:0004923 uberon 形成一层结构的器官的一部分壁。 external female genitalia An external genitalia that is part of a female reproductive system [Automatically generated definition]. external female genital organ external genitalia of female reproductive system female external genitalia organa genitalia feminina externa muscle structure muscle structure 肌肉结构 EMAPA:32715 FBbt:00005073 FMA:30316 Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. UBERON:0005090 in some organisms such as drosophila, muscles can be single cells. This class groups together all discrete muscle elements, from multicellular muscle organs in vertebrates, to individual single-cell muscles in drisophila muscle muscle element musculus uberon Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. muscle muscle element musculus 肌肉 肌肉(musculus) 肌肉元素 肌肉结构是在多细胞生物中发现的收缩细胞、组织或器官[GO]。 reproductive structure reproductive structure 生殖结构 Any anatomical structure that is part of the reproductive system. UBERON:0005156 UBERON:0005156 reproductive system element reproductive system element reproductive system structure reproductive system structure uberon uberon Any anatomical structure that is part of the reproductive system. UBERON:0005156 reproductive system element reproductive system element reproductive system structure reproductive system structure uberon 是生殖系统一部分的任何解剖结构。 生殖系统元素 生殖系统元素 生殖系统结构 生殖系统结构 multi cell part structure multi cell part structure 多细胞部分结构 A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. AAO:0011000 CARO:0001000 FBbt:00007060 FMA:83115 UBERON:0005162 cell part cluster cell part cluster multi-cell-component structure multi-cell-component structure multi-cell-part structure multi-cell-part structure uberon we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.' A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. AAO:0011000 CARO:0001000 FBbt:00007060 FMA:83115 UBERON:0005162 cell part cluster multi-cell-component structure multi-cell-part structure uberon we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.' 一个由多个细胞组成的结构，但它本身不是一个细胞，并且没有（完整的）细胞作为它的一部分。 多细胞组分结构 多细胞部分结构 我们采用的是FMA分类，而不是CARO分类。FMA def:'解剖簇，具有来自两个或更多细胞的直接细胞部分。' 细胞部分集群 trunk region element trunk region element 躯干区元素 An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. MA:0000516 UBERON:0005177 trunk organ trunk organ uberon An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. MA:0000516 UBERON:0005177 trunk organ trunk organ uberon 躯干区域一部分的器官或元素。躯干部位可进一步细分为胸部（包括胸腔和胸腔）和腹部（包括腹部和皮质）区域。 躯干器官 躯干器官 thoracic cavity element thoracic cavity element 胸腔元素 An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. thoracic cavity organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. thoracic cavity organ 胸腔内的器官或元件。例如：肺、心、长骨。 胸腔器官 thoracic segment organ thoracic segment organ 胸段器官 An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. MA:0000563 UBERON:0005181 uberon upper body organ upper body organ An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. MA:0000563 UBERON:0005181 uberon upper body organ upper body organ 上身器官 上身器官 是胸部区域一部分的器官。这个区域可以进一步细分为胸部和胸腔区域。 trunk mesenchyme Mesenchyme that is part of a developing trunk. trunk and cervical mesenchyme embryonic tissue embryonic tissue 胚胎组织 A portion of tissue that is part of an embryo. developing tissue portion of embryonic tissue A portion of tissue that is part of an embryo. developing tissue portion of embryonic tissue 发育组织(developing tissue) 是胚胎一部分的组织一部分。 胚胎组织的一部分 nasal cavity epithelium An epithelium that lines the nasal cavity. CALOHA:TS-0656 EHDAA2:0001227 EHDAA:6803 EMAPA:17605 FMA:63140 MA:0001324 NCIT:C49261 UBERON:0005384 UMLS:C1709151 VHOG:0000501 nasal epithelium nasal mucosa this class may in future be split into the embryonic precursor of the oronasal membrane and the structure that is part of the mucosa in the developed organism uberon male reproductive gland A sex gland that is part of a male reproductive system. BTO:0000080 EMAPA:19285 MA:0000399 UBERON:0005399 accessory sex gland uberon developing anatomical structure developing anatomical structure 发育解剖结构 AEO:0000125 AEO:0000125 CALOHA:TS-2122 CALOHA:TS-2122 EHDAA2:0003125 EHDAA2:0003125 FBbt:00007006 FBbt:00007006 FMA:292313 FMA:292313 MIAA:0000019 MIAA:0000019 UBERON:0005423 UBERON:0005423 developing structure developing structure developmental structure developmental structure developmental tissue developmental tissue uberon uberon AEO:0000125 CALOHA:TS-2122 EHDAA2:0003125 FBbt:00007006 FMA:292313 MIAA:0000019 UBERON:0005423 developing structure developing structure developmental structure developmental structure developmental tissue developmental tissue uberon 发育组织 发育组织 发育结构(developing structure) 发育结构(developing structure) 发育结构(developmental structure) 发育结构(developmental structure) primitive heart tube Multi-tissue structure that arises from the heart rudiment and will become the heart tube. early primitive heart tube primitive heart tube gonad primordium gonad primordium 生殖腺原基 Portion of tissue that gives rise to the immature gonad. future gonad gonadal primordium immature gonad primitive gonad undifferentiated gonad Portion of tissue that gives rise to the immature gonad. future gonad gonadal primordium immature gonad primitive gonad undifferentiated gonad 产生未成熟性腺的组织部分。 原始性腺 性腺原基(gonadal primordium) 未分化的性腺 未成熟的性腺 未来的性腺 acellular membrane acellular membrane 脱细胞膜 A acellular anatomical structure that is the bounding layer of a anatomical structure. A acellular anatomical structure that is the bounding layer of a anatomical structure. 是解剖结构的边界层的无细胞解剖结构。 basement membrane of epithelium basement membrane of epithelium 上皮基底膜 An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. basement membrane basement membrane of connective tissue membrana basalis An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. basement membrane basement membrane of connective tissue membrana basalis 基底膜(basement membrane) 基底膜(membrana basalis) 是上皮一部分的脱细胞膜位于上皮细胞的附近，它是基底层和网状层的融合。 结缔组织基底膜 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme. mesenchyme condensation undifferentiated genital tubercle genital tubercle phallic tubercle the embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin tuberculum genitale tuberculum phallicum undifferentiated genital tubercle endo-epithelium Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA] FMA:69065 UBERON:0005911 endoderm-derived epithelium endoepithelium uberon axial skeleton plus cranial skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. skeleton axiale integumentary adnexa Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. EMAPA:37883 UBERON:0006003 add subclasses based on resolution of CARO tracker item. Also check: adnexal gland. Note that MP implicitly includes hypodermis. adnexae cutis body hair or bristle skin adnexa skin adnexal structure skin appendage the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails[MP:0010678] uberon female genital tubercle A differentiated genital tubercle that is part of a female reproductive system. genital tubercle of female male genital tubercle A differentiated genital tubercle that is part of a male reproductive system. genital tubercle of male penis anlage bodily fluid bodily fluid 体液 EMAPA:37441 FMA:280556 FMA:280556 GAID:266 GAID:266 Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. MESH:D001826 MESH:D001826 UBERON:0006314 UBERON:0006314 body fluid body fluid fluid fluid galen:BodyFluid galen:BodyFluid uberon uberon FMA:280556 GAID:266 Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. MESH:D001826 UBERON:0006314 body fluid body fluid fluid fluid galen:BodyFluid uberon 体液 体液 活生物体的液体成分。包括从身体排泄或分泌的液体以及通常不会从身体排泄或分泌的的体液。 流体 流体 pharynx pharynx 咽 The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. anterior part of foregut pharyngeal tube The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. anterior part of foregut pharyngeal tube 前肠的前部 咽管 咽部是紧接在口腔后部的消化系统的一部分[GO]。 presumptive endoderm Presumptive structure of the blastula that will develop into endoderm. presumptive blood future blood presumptive structure presumptive structure 推定结构 Portion of embryonic tissue determined by fate mapping to become a structure. future structure presumptive structures Portion of embryonic tissue determined by fate mapping to become a structure. future structure presumptive structures 推定结构 未来的结构 由命运决定的胚胎组织的一部分，映射成为一个结构。 presumptive ectoderm Presumptive structure of the blastula that will develop into ectoderm. presumptive epidermis presumptive mesoderm Presumptive structure of the blastula that will develop into mesoderm. terminal part of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. rectal part of digestive tract rectum terminal section of digestive tract sensory epithelium CALOHA:TS-0682 FMA:62410 Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. UBERON:0006934 neuroepithelium note that the definition sourced from Dorlands say 'simple columnar', but FMA says atypical uberon vascular cord vascular cord 血管性脊髓 The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. 血管束是通过血管生成过程发展成血管的原始脉管系统[GO]。血管束由成血管细胞或血管内皮细胞组成，而血管内皮细胞在称为索的实心线状团块中。然后绳索经历血管生成以形成血管的内腔[ZFA]。 cardiogenic splanchnic mesoderm The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. cardiac mesoderm cardiogenic mesoderm cardiogenic region cardiogenic splanchnopleure heart primordia cleaving embryo Organism at the cleavage stage. presumptive gut presumptive gut 推定肠 embryonic digestive tube future digestive tract future digestive tube future gut primitive gut primordial digestive tube primordial gut embryonic digestive tube future digestive tract future digestive tube future gut primitive gut primordial digestive tube primordial gut 原始消化管 原始肠道(primitive gut) 原始肠道(primordial gut) 未来的消化管 未来的消化道 未来的肠道 胚胎消化管 primary circulatory organ primary circulatory organ 初级循环器官 A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. adult heart dorsal tube heart A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. adult heart dorsal tube heart 一个中空的肌肉器官，通过有节奏的收缩，保持血液或类似物的循环[GO，修改]。 心 成人心脏 背管 presumptive segmental plate A presumptive structure that has the potential to develop into a presomitic mesoderm. presumptive segmental plates presumptive paraxial mesoderm The part of the blastula that has the potential to develop into a paraxial mesoderm. future paraxial mesenchyme future paraxial mesoderm outer epithelium outer epithelium 外层上皮 BSA:0000073 BTO:0000313 FBbt:00004993 HAO:0000298 TADS:0000109 The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. UBERON:0007376 WBbt:0005733 epidermis epidermis epidermis (sensu Metazoa) epidermis (sensu Metazoa) hypoderm hypoderm hypodermis hypodermis outer epidermal layer outer epidermal layer outer epithelial layer outer epithelial layer this grouping class exists primarily to align with GO - see GO:0008544. uberon BSA:0000073 BTO:0000313 FBbt:00004993 HAO:0000298 TADS:0000109 The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. UBERON:0007376 WBbt:0005733 epidermis epidermis epidermis (sensu Metazoa) epidermis (sensu Metazoa) hypoderm hypoderm hypodermis hypodermis outer epidermal layer outer epidermal layer outer epithelial layer outer epithelial layer this grouping class exists primarily to align with GO - see GO:0008544. uberon 外表皮层 外表皮层 外部上皮层 外部上皮层 皮下组织(hypoderm) 皮下组织(hypoderm) 皮下组织(hypodermis) 皮下组织(hypodermis) 表皮 表皮 表皮(sensu Metazoa) 表皮(sensu Metazoa) 表皮是动物的整个外部上皮层，它可以是产生一种细胞外物质（例如节肢动物的角质层）或复杂复层鳞状上皮的单层，如在许多脊椎动物物种的案例中[GO]。 这个分组类主要是为了与GO保持一致，参见GO：0008544。 enveloping layer of ectoderm enveloping layer of ectoderm 外胚层包膜层 EVL Outermost layer of cells surrounding the embryo. enveloping layer EVL Outermost layer of cells surrounding the embryo. enveloping layer 周围层 胚胎周围最外层的细胞。 epithelial tube open at both ends epithelial tube open at both ends 两端开口的上皮管 An epithelial tube open at both ends that allows fluid flow. An epithelial tube open at both ends that allows fluid flow. 允许液体流动的两端开放的上皮管。 epithelial vesicle A closed epithelium with a lumen. dense mesenchyme tissue dense mesenchyme tissue 密集间充质组织 Mesenchyme with little extracellular matrix. Mesenchyme with little extracellular matrix. 具有少量细胞外基质的间质细胞。 migrating mesenchyme population migrating mesenchyme population 迁移间充质种群 Mesenchymal cells that are migrating. Mesenchymal cells that are migrating. 正在迁移的间充质细胞。 ciliated columnar epithelium Ciliated columnar epithelium in the pulmonary system is interspersed with goblet cells that secrete mucous to form a mucosal layer apical to the epithelial layer. The rowing-like action of epithelial cilia work in tandem with goblet cells to propel mucus away from the lungs, preventing particulate matter from causing infection[http://www.bio.davidson.edu/people/kabernd/berndcv/lab/epithelialinfoweb/ciliated%20columnar%20epithelium.html] FMA:64798 In humans, Ciliated columnar epithelial cells are found mainly in the tracheal and bronchial regions of the pulmonary system and also in the fallopian tubes of the female reproductive system Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA] UBERON:0007592 uberon ciliated epithelium Epithelium bearing vibratile cilia on the free surface. UBERON:0007601 uberon anlage Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. developmental field field future organ organ field vascular system vascular system 血管系统 Anatomical system that consists of all blood and lymph vessels. Gefaesssystem@de Anatomical system that consists of all blood and lymph vessels. Gefaesssystem@ge 由所有血液和淋巴管组成的解剖系统。 craniocervical region craniocervical region 颅颈部区域 The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. cephalic area cephalic part of animal cephalic region head and neck head or neck The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. cephalic area cephalic part of animal cephalic region head and neck head or neck 动物头部的一部分 包括头部、下颌、咽部和颈部（如果存在）的身体的最前面的细分。在脊椎动物这是包括颈椎的细分。 头和脖子 头或脖子 头部区域 头部区域(cephalic region) intromittent organ An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]. aedeagus copulatory organ penis entire embryonic mesenchyme entire embryonic mesenchyme 整个胚胎间充质 Sum total of mesenchyme in the embryo. Sum total of mesenchyme in the embryo. 胚胎中的间充质总和。 indifferent external genitalia indifferent external genitalia 未分化外部生殖器 subdivision of trunk subdivision of trunk 躯干分支 region of trunk trunk subdivision region of trunk trunk subdivision 躯干区域 躯干细分 trunk paraxial mesoderm trunk and cervical paraxial mesenchyme trunk paraxial mesenchyme anterior lateral plate mesoderm ALPM multicellular anatomical structure multicellular anatomical structure 多细胞解剖结构 An anatomical structure that has more than one cell as a part. CARO:0010000 CARO:0010000 FBbt:00100313 FBbt:00100313 UBERON:0010000 UBERON:0010000 multicellular structure multicellular structure uberon uberon An anatomical structure that has more than one cell as a part. CARO:0010000 FBbt:00100313 UBERON:0010000 multicellular structure multicellular structure uberon 具有多个细胞作为其一部分的解剖结构。 多细胞结构 多细胞结构 future dermis Mesenchyme that has the potential to develop into a dermis. male accessory sex gland Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male. BTO:0004798 UBERON:0010147 male accessory gland male accessory reproductive gland uberon structure with developmental contribution from neural crest structure with developmental contribution from neural crest 神经嵴发育的结构 An anatomical structure that has some part that develops from the neural crest. Grouping term for query purposes UBERON:0010314 UBERON:0010314 uberon uberon An anatomical structure that has some part that develops from the neural crest. Grouping term for query purposes UBERON:0010314 uberon 有一部分是从神经嵴发育而来的解剖结构。 用于查询目的分组术语 germ layer / neural crest germ layer / neural crest 胚层/神经嵴 ecto-epithelium ecto-epithelium 外胚上皮 Epithelium composed of cells that develops from the ectoderm[FMA,modified]. FMA:69064 FMA:69064 UBERON:0010371 UBERON:0010371 ectoderm-derived epithelium ectoderm-derived epithelium uberon uberon Epithelium composed of cells that develops from the ectoderm[FMA,modified]. FMA:69064 UBERON:0010371 ectoderm-derived epithelium ectoderm-derived epithelium uberon 外胚层来源的上皮细胞 外胚层来源的上皮细胞 由外胚层发展而来的细胞组成的上皮细胞[FMA，modified]。 pseudostratified columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. FMA:45572 NCIT:C33419 NCIT:C49316 Pseudostratified epithelia function in secretion or absorption. If a specimen looks stratified but has cilia, then it is a pseudostratified ciliated epithelium, since stratified epithelia do not have cilia. UBERON:0010498 UMLS:C0836138 UMLS:C1514590 glandular in NCIT; we consider the two NCIT terms synonymous uberon pseudostratified ciliated columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. FMA:13146 NCIT:C13181 UBERON:0010499 UMLS:C0506992 epithelium pseudostratificatum columnare ciliatum (trachea et bronchi) uberon pectoral complex muscle A muscle of a pectoral girdle, pectoral fin or anterior limb. AAO:0010687 EMAPA:32624 FMA:9621 MA:0000615 Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO] UBERON:0010891 muscle of pectoral girdle and limb muscle of pectoral girdle and wing muscle of upper limb pectoral complex muscle pectoral girdle and fore limb muscles the MA class belongs here, based on its current child classes uberon upper limb muscle subdivision of skeleton Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. skeletal subdivision subdivision of skeleton (in vivo) nonsynovial joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. solid joint axial skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. postcranial axial skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system post-cranial axial skeletal system organ system subdivision organ system subdivision 器官系统细分 A subdivision of an anatomical system. FBbt:00007330 FMA:67509 UBERON:0011216 uberon A subdivision of an anatomical system. FBbt:00007330 FMA:67509 UBERON:0011216 uberon 解剖系统的细分。 embryonic skin basal layer basal cell layer of skin outer epithelium of body prepuce A retractable double-layered fold of skin and mucous membrane that covers the glans penis or clitoris. Glands may also be present. UBERON:0011374 preputial this is a generic sex-neutral grouping class for the male and female prepuce. Note that this structure is a combination of skin and other tissue uberon cell condensation Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). subdivision of organism along main body axis subdivision of organism along main body axis 生物体沿主体轴的分支 A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. Ideally this would be disjoint with analagous class for appendicular axes, but currently 'appendages' like antennae, horns cause a problem UBERON:0011676 axial subdivision of organism axial subdivision of organism body segment body segment main body segment main body segment uberon A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. Ideally this would be disjoint with analagous class for appendicular axes, but currently 'appendages' like antennae, horns cause a problem UBERON:0011676 axial subdivision of organism axial subdivision of organism body segment body segment main body segment main body segment uberon 主体部分 主体部分 沿着其主体轴线（通常是前-后轴）划分生物体的生物体主要细分。在脊椎动物，这是基于脊柱。 理想情况下，这将与附属轴的类别不相交，但是目前的“附属物” 像天线、喇叭一样引起一个问题 生物体的轴向细分 生物体的轴向细分 身体部分 身体部分 embryonic cardiovascular system embryonic cardiovascular system 胚胎心血管系统 A cardiovascular system that is part of a conceptus. conceptus cardiovascular system embryonic circulatory system fetal circulatory system A cardiovascular system that is part of a conceptus. conceptus cardiovascular system embryonic circulatory system fetal circulatory system 是一个孕体一部分的心血管系统。 胎体心血管系统 胎儿循环系统 胚胎循环系统 differentiated genital tubercle . phallus phallus primordialis primordial phallus irregular connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. dense irregular connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. irregular dense connective tissue typus irregularis (textus connectivus collagenosus compactus) dense connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets loose connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. textus connectivus collagenosus laxus textus connectivus laxus collection of collagen fibrils umbilical cord blood BTO:0004053 CALOHA:TS-1079 Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders.[WP] EFO:0001942 MESH:D005312 UBERON:0012168 blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. cord blood fetal blood uberon umbilical cord blood columnar epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified] UBERON:0012274 uberon meso-epithelium meso-epithelium 中胚层来源上皮 Epithelium that derives from the mesoderm. [Automatically generated definition]. FMA:86452 UBERON:0012275 mesoderm-derived epithelium mesoderm-derived epithelium mesoepithelium mesoepithelium uberon Epithelium that derives from the mesoderm. [Automatically generated definition]. FMA:86452 UBERON:0012275 mesoderm-derived epithelium mesoderm-derived epithelium mesoepithelium mesoepithelium uberon 中胚层来源的上皮细胞 中胚层来源的上皮细胞 来自中胚层的上皮细胞。 [自动生成的定义]。 embryonic cloacal fold One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly cloacal fold hematopoietic tissue hemopoietic tissue 造血组织 Blood-forming tissue, consisting of reticular fibers and cells. bone marrow tissue haemopoietic tissue hematopoietic tissue hemopoietic tissue textus haemopoieticus Blood-forming tissue, consisting of reticular fibers and cells. Also known as hemopoietic tissue bone marrow tissue haemopoietic tissue hematopoietic tissue textus haemopoieticus 形成血液的组织，由网状纤维和细胞组成。也被称为造血组织 造血组织(haemopoietic tissue) 造血组织(hematopoietic tissue) 骨髓组织 external anal region subdivision of tube subdivision of tube 管分支 UBERON:0013522 uberon UBERON:0013522 uberon anatomical conduit space anatomical conduit space 解剖导管空间 An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. foramen space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. foramen space 一个解剖学空间，它是一些解剖导管的腔，连接两个或更多的空间[FMA，修改]。 孔空间 main body axis main body axis 主体轴 A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. 一个生物体的一种主要细分，包括沿主轴的所有结构，通常是前后轴，从头到尾，包括身体本身（例如肋骨）的结构，但不包括附肢。 body proper body proper 身体本身 The region of the organism associated with the visceral organs. body whole body The region of the organism associated with the visceral organs. body whole body 与脏器相关的生物体区域。 全身 身体 integumentary projection Anatomical projection that is part of the integumentl system. UBERON:0013703 UBERON:0013703 skin projection skin projection uberon uberon integumentary system layer A organ component layer that is part of a integumental system. UBERON:0013754 layer of skin layer of skin skin layer skin layer uberon thoracic skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. skeleton of thorax thoracic part of axial skeleton thoracic skeleton pectoral appendage muscle Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). UBERON:0014794 uberon skeletal muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). AAO:0011099 BTO:0001103 CALOHA:TS-0933 EFO:0000888 EHDAA:5035 EHDAA:5043 EHDAA:5978 EHDAA:5984 EMAPA:35988 EV:0100377 GAID:141 MA:0003148 MAT:0000302 MESH:D018482 MIAA:0000302 OpenCyc:Mx4rv2kf-5wpEbGdrcN5Y29ycA TAO:0005277 UBERON:0014892 VHOG:0000319 XAO:0000174 ZFA:0005277 skeletal muscle uberon primordial vasculature primordial vasculature 原始脉管系统 A portion of tissue that will develop into vasculature. A portion of tissue that will develop into vasculature. 将发展成脉管系统的组织的一部分。 lateral structure lateral structure 横向结构 Any structure that is placed on one side of the left-right axis of a bilaterian. This class is primarily to implement taxon constraints. It may be removed in the future. UBERON:0015212 uberon Any structure that is placed on one side of the left-right axis of a bilaterian. This class is primarily to implement taxon constraints. It may be removed in the future. UBERON:0015212 uberon 放置在一个双侧壁左右轴一侧的任何结构。 这个类主要是为了实施分类学的限制。 它可能在将来被删除。 circulatory organ circulatory organ 循环器官 A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. cardiac pump cardiac structure circulatory vessel heart heart or heart like organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. cardiac pump cardiac structure circulatory vessel heart heart or heart like organ 一个中空的肌肉器官，通过有节奏地收缩，有助于淋巴、血液或类似物的循环。例如：一个有脊椎动物的心脏；海鞘的管状蠕动心脏；一种昆虫的背部血管；一种爬行动物的淋巴心。 循环血管 心 心脏或心脏样器官 心脏泵 心脏结构 heart plus pericardium heart plus pericardium 心脏和心包 heart/pericardium heart/pericardium 心脏/心包 heterogeneous tissue heterogeneous tissue 异形组织 portion of heterogeneous tissue portion of heterogeneous tissue 部分异质组织 future central nervous system future central nervous system 原中枢神经系统 Primordium that develops into the central nervous system future CNS presumptive central nervous system Primordium that develops into the central nervous system future CNS presumptive central nervous system 原基发育成中枢神经系统 推定的中枢神经系统 未来的CNS future nervous system future nervous system 原神经系统 Primordium that develops into the nervous system presumptive nervous system Primordium that develops into the nervous system presumptive nervous system 发育成神经系统的原基 推定的神经系统 entire extraembryonic component entire extraembryonic component 整个胚外组分 The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. extra-embryonic component extraembryonic component The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. extra-embryonic component extraembryonic component 胚外组分(extra-embryonic component) 胚外组分(extraembryonic component) 这个概念的一部分可能会在出生之前丢失或在出生时，或者胚胎成为独立的生物体时被丢弃。 transitional anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. developing mesenchymal structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. sensory organ epithelium EMAPA:35952 MA:0003174 UBERON:0019304 uberon nose epithelium EMAPA:35958 MA:0003171 UBERON:0019306 uberon morphological feature A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. UBERON:0034768 uberon lymphomyeloid tissue lymphomyeloid tissue 淋巴样组织 multi organ part structure multi organ part structure 多器官部分结构 An multicellular anatomical structure that has subparts of multiple organs as a part. CARO:0020001 UBERON:0034921 anatomical cluster anatomical cluster uberon An multicellular anatomical structure that has subparts of multiple organs as a part. CARO:0020001 UBERON:0034921 anatomical cluster uberon 具有多个器官子部分作为其一部分的多细胞解剖结构。 解剖簇 anatomical collection anatomical collection 解剖采集 A collection of anatomical structures that are alike in terms of their morphology or developmental origin. A collection of anatomical structures that are alike in terms of their morphology or developmental origin. 在形态或发育起源方面相似的解剖结构的集合。 external soft tissue zone external soft tissue zone 外部软组织区域 A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. UBERON:0034929 UBERON:0034929 uberon uberon A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. UBERON:0034929 uberon 生物体表面上的一个地区或区域，包括皮肤和附属物，向下穿过肌肉，并由下面的骨骼支撑结构界定。 zone of organ zone of organ 器官区 FMA:55268 FMA:55268 UBERON:0034944 UBERON:0034944 organ region with floating fiat boundary organ region with floating fiat boundary organ sector organ sector organ zonal region organ zonal region organ zone organ zone uberon uberon FMA:55268 UBERON:0034944 organ region with floating fiat boundary organ sector organ zonal region organ zone uberon 器官区 器官带状区域 器官部分(organ sector) 带有浮动边界器官区域 preputial swelling preputial swelling of male prepuce of male cardiopharyngeal field An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. external integument structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. disease disease 疾病 A disease is a disposition that describes states of disease associated with a particular sample and/or organism. James Malone A disease is a disposition that describes states of disease associated with a particular sample and/or organism. James Malone 疾病是与特定样本和/或生物体有关的疾病状态的描述。 organism part organism part 生物体一部分 James Malone Jie Zheng MO_954 The part of organism's anatomy or substance arising from an organism from which the biomaterial was derived, excludes cells. E.g. tissue, organ, system, sperm, blood or body location (arm). Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#organism_part tissue, organ, system, sperm, blood or body location (arm). James Malone Jie Zheng MO_954 The part of organism's anatomy or substance arising from an organism from which the biomaterial was derived, excludes cells. E.g. tissue, organ, system, sperm, blood or body location (arm). Tomasz Adamusiak URI: http://www.ebi.ac.uk/cellline#organism_part tissue, organ, system, sperm, blood or body location (arm). 从生物材料来源的生物体产生的生物体的部分解剖结构或物质不包括细胞。 例如。 组织，器官，系统，精子，血液或身体部位（手臂）。 组织，器官，系统，精子，血液或身体部位（手臂）。 appendage James Malone MAT:0000023 URI: http://www.ebi.ac.uk/cellline#appendage animal reproductive system animal reproductive system 动物生殖系统 EHDAA:5923 EMAPA:17381 EV:0100100 FBbt:00004857 FMAID:7160 James Malone MAT:0000305 Reproductive system SAEL:89 TAO:0000632 URI: http://www.ebi.ac.uk/cellline#animal_reproductive_system XAO:0000142 genital system reproductive system - animals EHDAA:5923 EMAPA:17381 EV:0100100 FBbt:00004857 FMAID:7160 James Malone MAT:0000305 Reproductive system SAEL:89 TAO:0000632 URI: http://www.ebi.ac.uk/cellline#animal_reproductive_system XAO:0000142 genital system reproductive system - animals 生殖系统(Reproductive system) 生殖系统(genital system) 生殖系统-动物 vertebrate limb Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with a complete set of bones of the appendicular skeleton, it is partially surrounded by skin of limb. Examples: There are only four instances, right upper and lower limbs and left upper and lower limbs. EHDAA:1697 EMAPA:16405 EV:0100483 Extremity FMAID:7182 James Malone MA:0000007 MAT:0000090 URI: http://www.ebi.ac.uk/cellline#vertebrate_limb XAO:0003027 limb limb sensu vertebrata vertebrata limb male reproductive system BTO:0000082 EHDAA:8136 EMAPA:17968 EV:0100101 FMAID:45664 Gonochoristic organism that can produce male gametes. James Malone MA:0000396 MAT:0000029 TADS:0000460 The reproductive system in men includes the prostate, the testes, and the penis. URI: http://www.ebi.ac.uk/cellline#male_reproductive_system WBbt:0005574 XAO:0000155 ZFA:0000242 male male genital system male genitalia penis A male organ of copulation that in male mammals including humans usually functions as the channel by which urine leaves the body. BTO:0000405 Distal part of the aedeagus consisting of a median, scleratised, pointed lobe through which the ejaculatory duct discharges. EHDAA:9380 EMAPA:18682 EV:0100107 FBbt:00004852 FMAID:9707 James Malone MA:0000408 MAT:0000186 SAEL:80 URI: http://www.ebi.ac.uk/cellline#penis phallus arm A human upper limb; especially: the part between the shoulder and the wrist. BTO:0001435 James Malone NCIt:C32141 The portion of the upper extremity between the shoulder and the elbow. For clinical purposes this term is also used to refer to the whole superior limb. URI: http://www.ebi.ac.uk/cellline#arm foreskin A fold of skin that covers the glans of the penis. BTO:0001113 James Malone URI: http://www.ebi.ac.uk/cellline#foreskin prepuce PCCSE The LINCS Proteomic Characterization Center for Signaling and Epigenetics at the Broad Institute http://www.lincsproject.org/LINCS/centers/data-and-signature-generating-centers/lincs-pccse SAMEA3174344 Stefanie Seltmann, Oliver He SNCA0912 G51D https://www.ebi.ac.uk/biosamples/samples/SAMEA3174344 This donor was used to generate several stem cell lines, including EDi008-A and EDi008-B. GS1D SAMEA103884150 Stefanie Seltmann, Yongqun He SAMEA103884152 Stefanie Seltmann, Yongqun He SAMEA103884154 Stefanie Seltmann, Yongqun He SAMEA103884159 Stefanie Seltmann, Yongqun He SAMEA103884161 Stefanie Seltmann, Yongqun He SAMEA103884796 Stefanie Seltmann, Yongqun He SAMEA103884799 Stefanie Seltmann, Yongqun He SAMEA103885562 Stefanie Seltmann, Yongqun He SAMEA103885564 Stefanie Seltmann, Yongqun He SAMEA103885566 Stefanie Seltmann, Yongqun He SAMEA103885569 Stefanie Seltmann, Yongqun He SAMEA103885930 Stefanie Seltmann, Yongqun He SAMEA103887517 Stefanie Seltmann, Yongqun He SAMEA103887534 Stefanie Seltmann, Yongqun He SAMEA103887536 Stefanie Seltmann, Yongqun He SAMEA103887556 Stefanie Seltmann, Yongqun He SAMEA103988341 Stefanie Seltmann, Yongqun He SAMEA103988350 Stefanie Seltmann, Yongqun He SAMEA103988359 Stefanie Seltmann, Yongqun He SAMEA103988370 Stefanie Seltmann, Yongqun He SAMEA103988371 Stefanie Seltmann, Yongqun He SAMEA103988372 Stefanie Seltmann, Yongqun He SAMEA103988373 Stefanie Seltmann, Yongqun He SAMEA103988374 Stefanie Seltmann, Yongqun He SAMEA103988375 Stefanie Seltmann, Yongqun He SAMEA103992706 Stefanie Seltmann, Yongqun He SAMEA103992801 Stefanie Seltmann, Yongqun He SAMEA103992813 Stefanie Seltmann, Yongqun He SAMEA103992831 Stefanie Seltmann, Yongqun He SAMEA103992833 Stefanie Seltmann, Yongqun He SAMEA103992835 Stefanie Seltmann, Yongqun He SAMEA104008499 Stefanie Seltmann, Yongqun He SAMEA104008501 Stefanie Seltmann, Yongqun He SAMEA104009425 Stefanie Seltmann, Yongqun He SAMEA104010450 Stefanie Seltmann, Yongqun He SAMEA104010736 Stefanie Seltmann, Yongqun He SAMEA104010737 Stefanie Seltmann, Yongqun He SAMEA104010850 Stefanie Seltmann, Yongqun He SAMEA104010908 Stefanie Seltmann, Yongqun He SAMEA104010910 Stefanie Seltmann, Yongqun He SAMEA104010912 Stefanie Seltmann, Yongqun He SAMEA104010914 Stefanie Seltmann, Yongqun He SAMEA104011170 Stefanie Seltmann, Yongqun He SAMEA104011276 Stefanie Seltmann, Yongqun He SAMEA104012033 Stefanie Seltmann, Yongqun He SAMEA104012190 Stefanie Seltmann, Yongqun He SAMEA104012324 Stefanie Seltmann, Yongqun He SAMEA104012325 Stefanie Seltmann, Yongqun He SAMEA104012326 Stefanie Seltmann, Yongqun He SAMEA104012327 Stefanie Seltmann, Yongqun He SAMEA104012328 Stefanie Seltmann, Yongqun He SAMEA104012329 Stefanie Seltmann, Yongqun He SAMEA104012353 Stefanie Seltmann, Yongqun He SAMEA104012399 Stefanie Seltmann, Yongqun He SAMEA104012401 Stefanie Seltmann, Yongqun He SAMEA104012403 Stefanie Seltmann, Yongqun He SAMEA104012405 Stefanie Seltmann, Yongqun He SAMEA104012407 Stefanie Seltmann, Yongqun He SAMEA104012409 Stefanie Seltmann, Yongqun He SAMEA104012411 Stefanie Seltmann, Yongqun He SAMEA104012413 Stefanie Seltmann, Yongqun He SAMEA104012415 Stefanie Seltmann, Yongqun He SAMEA104012417 Stefanie Seltmann, Yongqun He SAMEA104012419 Stefanie Seltmann, Yongqun He SAMEA104012421 Stefanie Seltmann, Yongqun He SAMEA104012531 Stefanie Seltmann, Yongqun He SAMEA104012533 Stefanie Seltmann, Yongqun He SAMEA104012535 Stefanie Seltmann, Yongqun He SAMEA104012536 Stefanie Seltmann, Yongqun He SAMEA104012538 Stefanie Seltmann, Yongqun He SAMEA104012951 Stefanie Seltmann, Yongqun He SAMEA104013011 Stefanie Seltmann, Yongqun He SAMEA104026331 Stefanie Seltmann, Yongqun He SAMEA104129730 Stefanie Seltmann, Yongqun He SAMEA104129751 Stefanie Seltmann, Yongqun He SAMEA104129753 Stefanie Seltmann, Yongqun He SAMEA104129930 Stefanie Seltmann, Yongqun He SAMEA104129950 Stefanie Seltmann, Yongqun He SAMEA104129951 Stefanie Seltmann, Yongqun He SAMEA104130289 Stefanie Seltmann, Yongqun He SAMEA104130511 Stefanie Seltmann, Yongqun He SAMEA104130513 Stefanie Seltmann, Yongqun He SAMEA104130515 Stefanie Seltmann, Yongqun He SAMEA104130517 Stefanie Seltmann, Yongqun He SAMEA104130519 Stefanie Seltmann, Yongqun He SAMEA104130521 Stefanie Seltmann, Yongqun He SAMEA104130523 Stefanie Seltmann, Yongqun He SAMEA104130525 Stefanie Seltmann, Yongqun He SAMEA104130551 Stefanie Seltmann, Yongqun He SAMEA104130591 Stefanie Seltmann, Yongqun He SAMEA104130931 Stefanie Seltmann, Yongqun He SAMEA104130952 Stefanie Seltmann, Yongqun He SAMEA104130971 Stefanie Seltmann, Yongqun He SAMEA104132641 Stefanie Seltmann, Yongqun He SAMEA104132810 Stefanie Seltmann, Yongqun He SAMEA104132870 Stefanie Seltmann, Yongqun He SAMEA104132876 Stefanie Seltmann, Yongqun He SAMEA104132931 Stefanie Seltmann, Yongqun He SAMEA104132951 Stefanie Seltmann, Yongqun He SAMEA104133813 Stefanie Seltmann, Yongqun He SAMEA104133815 Stefanie Seltmann, Yongqun He SAMEA104133817 Stefanie Seltmann, Yongqun He SAMEA104133819 Stefanie Seltmann, Yongqun He SAMEA104133951 Stefanie Seltmann, Yongqun He SAMEA104134611 Stefanie Seltmann, Yongqun He SAMEA104134631 Stefanie Seltmann, Yongqun He SAMEA104134951 Stefanie Seltmann, Yongqun He SAMEA104135251 Stefanie Seltmann, Yongqun He SAMEA104235581 Stefanie Seltmann, Yongqun He SAMEA104235611 Stefanie Seltmann, Yongqun He SAMEA104235616 Stefanie Seltmann, Yongqun He SAMEA104236751 Stefanie Seltmann, Yongqun He SAMEA104236753 Stefanie Seltmann, Yongqun He SAMEA104236755 Stefanie Seltmann, Yongqun He SAMEA104236757 Stefanie Seltmann, Yongqun He SAMEA104236910 Stefanie Seltmann, Yongqun He SAMEA104236912 Stefanie Seltmann, Yongqun He SAMEA104242073 Stefanie Seltmann, Yongqun He SAMEA104243151 Stefanie Seltmann, Yongqun He SAMEA104243153 Stefanie Seltmann, Yongqun He SAMEA104243178 Stefanie Seltmann, Yongqun He SAMEA104271471 Stefanie Seltmann, Yongqun He SAMEA104275575 Stefanie Seltmann, Yongqun He SAMEA104275579 Stefanie Seltmann, Yongqun He SAMEA104381151 Stefanie Seltmann, Yongqun He SAMEA104381171 Stefanie Seltmann, Yongqun He SAMEA104381175 Stefanie Seltmann, Yongqun He SAMEA104381571 Stefanie Seltmann, Yongqun He SAMEA104382071 Stefanie Seltmann, Yongqun He SAMEA104382073 Stefanie Seltmann, Yongqun He SAMEA104382075 Stefanie Seltmann, Yongqun He SAMEA104382151 Stefanie Seltmann, Yongqun He SAMEA104382171 Stefanie Seltmann, Yongqun He SAMEA104384831 Stefanie Seltmann, Yongqun He SAMEA104384833 Stefanie Seltmann, Yongqun He SAMEA104386350 Stefanie Seltmann, Yongqun He SAMEA104387751 Stefanie Seltmann, Yongqun He SAMEA104387753 Stefanie Seltmann, Yongqun He SAMEA104387770 Stefanie Seltmann, Yongqun He SAMEA104387911 Stefanie Seltmann, Yongqun He SAMEA104387931 Stefanie Seltmann, Yongqun He SAMEA104387933 Stefanie Seltmann, Yongqun He SAMEA104387971 Stefanie Seltmann, Yongqun He SAMEA104387973 Stefanie Seltmann, Yongqun He SAMEA104387975 Stefanie Seltmann, Yongqun He SAMEA104387977 Stefanie Seltmann, Yongqun He SAMEA104388070 Stefanie Seltmann, Yongqun He SAMEA104388091 Stefanie Seltmann, Yongqun He SAMEA104388411 Stefanie Seltmann, Yongqun He SAMEA104491351 Stefanie Seltmann, Yongqun He SAMEA104491451 Stefanie Seltmann, Yongqun He SAMEA104491454 Stefanie Seltmann, Yongqun He SAMEA104491591 Stefanie Seltmann, Yongqun He SAMEA104492930 Stefanie Seltmann, Yongqun He SAMEA104493011 Stefanie Seltmann, Yongqun He SAMEA104493015 Stefanie Seltmann, Yongqun He SAMEA104493311 Stefanie Seltmann, Yongqun He SAMEA104493313 Stefanie Seltmann, Yongqun He SAMEA104493316 Stefanie Seltmann, Yongqun He SAMEA104493601 Stefanie Seltmann, Yongqun He SAMEA104493605 Stefanie Seltmann, Yongqun He SAMEA104493607 Stefanie Seltmann, Yongqun He SAMEA104493611 Stefanie Seltmann, Yongqun He SAMEA104493615 Stefanie Seltmann, Yongqun He SAMEA104493618 Stefanie Seltmann, Yongqun He SAMEA104493622 Stefanie Seltmann, Yongqun He SAMEA104493626 Stefanie Seltmann, Yongqun He SAMEA104493630 Stefanie Seltmann, Yongqun He SAMEA104493634 Stefanie Seltmann, Yongqun He SAMEA104493638 Stefanie Seltmann, Yongqun He SAMEA104493641 Stefanie Seltmann, Yongqun He SAMEA104493649 Stefanie Seltmann, Yongqun He SAMEA104493653 Stefanie Seltmann, Yongqun He SAMEA104493657 Stefanie Seltmann, Yongqun He SAMEA104493661 Stefanie Seltmann, Yongqun He SAMEA104493663 Stefanie Seltmann, Yongqun He SAMEA104493666 Stefanie Seltmann, Yongqun He SAMEA104493670 Stefanie Seltmann, Yongqun He SAMEA104493673 Stefanie Seltmann, Yongqun He SAMEA104493676 Stefanie Seltmann, Yongqun He SAMEA104493679 Stefanie Seltmann, Yongqun He SAMEA104493682 Stefanie Seltmann, Yongqun He SAMEA104493686 Stefanie Seltmann, Yongqun He SAMEA104493688 Stefanie Seltmann, Yongqun He SAMEA104493690 Stefanie Seltmann, Yongqun He SAMEA104493692 Stefanie Seltmann, Yongqun He SAMEA104493696 Stefanie Seltmann, Yongqun He SAMEA104493701 Stefanie Seltmann, Yongqun He SAMEA104493704 Stefanie Seltmann, Yongqun He SAMEA104493707 Stefanie Seltmann, Yongqun He SAMEA104493711 Stefanie Seltmann, Yongqun He SAMEA104493715 Stefanie Seltmann, Yongqun He SAMEA104493721 Stefanie Seltmann, Yongqun He SAMEA104493724 Stefanie Seltmann, Yongqun He SAMEA104493726 Stefanie Seltmann, Yongqun He SAMEA104493728 Stefanie Seltmann, Yongqun He SAMEA104493730 Stefanie Seltmann, Yongqun He SAMEA104493735 Stefanie Seltmann, Yongqun He SAMEA104493738 Stefanie Seltmann, Yongqun He SAMEA104493740 Stefanie Seltmann, Yongqun He SAMEA104493742 Stefanie Seltmann, Yongqun He SAMEA104493746 Stefanie Seltmann, Yongqun He SAMEA104493749 Stefanie Seltmann, Yongqun He SAMEA104493752 Stefanie Seltmann, Yongqun He SAMEA104493760 Stefanie Seltmann, Yongqun He SAMEA104493763 Stefanie Seltmann, Yongqun He SAMEA104493767 Stefanie Seltmann, Yongqun He SAMEA104493771 Stefanie Seltmann, Yongqun He SAMEA104493786 Stefanie Seltmann, Yongqun He SAMEA104493788 Stefanie Seltmann, Yongqun He SAMEA104493790 Stefanie Seltmann, Yongqun He SAMEA104493794 Stefanie Seltmann, Yongqun He SAMEA104493796 Stefanie Seltmann, Yongqun He SAMEA104493798 Stefanie Seltmann, Yongqun He SAMEA104493803 Stefanie Seltmann, Yongqun He SAMEA104493807 Stefanie Seltmann, Yongqun He SAMEA104493810 Stefanie Seltmann, Yongqun He SAMEA104493812 Stefanie Seltmann, Yongqun He SAMEA104493814 Stefanie Seltmann, Yongqun He SAMEA104493818 Stefanie Seltmann, Yongqun He SAMEA104493821 Stefanie Seltmann, Yongqun He SAMEA104493824 Stefanie Seltmann, Yongqun He SAMEA104493827 Stefanie Seltmann, Yongqun He SAMEA104493829 Stefanie Seltmann, Yongqun He SAMEA104493832 Stefanie Seltmann, Yongqun He SAMEA104493836 Stefanie Seltmann, Yongqun He SAMEA104493840 Stefanie Seltmann, Yongqun He SAMEA104493848 Stefanie Seltmann, Yongqun He SAMEA104493851 Stefanie Seltmann, Yongqun He SAMEA104493857 Stefanie Seltmann, Yongqun He SAMEA104493860 Stefanie Seltmann, Yongqun He SAMEA104493862 Stefanie Seltmann, Yongqun He SAMEA104493867 Stefanie Seltmann, Yongqun He SAMEA104493872 Stefanie Seltmann, Yongqun He SAMEA104493879 Stefanie Seltmann, Yongqun He SAMEA104493883 Stefanie Seltmann, Yongqun He SAMEA104493887 Stefanie Seltmann, Yongqun He SAMEA104493889 Stefanie Seltmann, Yongqun He SAMEA104493894 Stefanie Seltmann, Yongqun He SAMEA104493898 Stefanie Seltmann, Yongqun He SAMEA104494111 Stefanie Seltmann, Yongqun He SAMEA104494351 Stefanie Seltmann, Yongqun He SAMEA104494406 Stefanie Seltmann, Yongqun He SAMEA104494410 Stefanie Seltmann, Yongqun He SAMEA104494414 Stefanie Seltmann, Yongqun He SAMEA104494418 Stefanie Seltmann, Yongqun He SAMEA104494771 Stefanie Seltmann, Yongqun He SAMEA104494772 Stefanie Seltmann, Yongqun He SAMEA104494775 Stefanie Seltmann, Yongqun He SAMEA104575906 Stefanie Seltmann, Yongqun He SAMEA104615890 Stefanie Seltmann, Yongqun He SAMEA104615897 Stefanie Seltmann, Yongqun He SAMEA104615902 Stefanie Seltmann, Yongqun He SAMEA104615903 Stefanie Seltmann, Yongqun He SAMEA104615904 Stefanie Seltmann, Yongqun He SAMEA104615905 Stefanie Seltmann, Yongqun He SAMEA104615907 Stefanie Seltmann, Yongqun He SAMEA104615910 Stefanie Seltmann, Yongqun He SAMEA104615911 Stefanie Seltmann, Yongqun He SAMEA104616124 Stefanie Seltmann, Yongqun He SAMEA104616126 Stefanie Seltmann, Yongqun He SAMEA104616128 Stefanie Seltmann, Yongqun He SAMEA104616130 Stefanie Seltmann, Yongqun He SAMEA104616132 Stefanie Seltmann, Yongqun He SAMEA104616134 Stefanie Seltmann, Yongqun He SAMEA104616136 Stefanie Seltmann, Yongqun He SAMEA104616138 Stefanie Seltmann, Yongqun He SAMEA104616140 Stefanie Seltmann, Yongqun He SAMEA104616145 Stefanie Seltmann, Yongqun He SAMEA104616147 Stefanie Seltmann, Yongqun He SAMEA104616149 Stefanie Seltmann, Yongqun He SAMEA104616152 Stefanie Seltmann, Yongqun He SAMEA104616156 Stefanie Seltmann, Yongqun He SAMEA104616158 Stefanie Seltmann, Yongqun He SAMEA104616160 Stefanie Seltmann, Yongqun He SAMEA104616162 Stefanie Seltmann, Yongqun He SAMEA104616166 Stefanie Seltmann, Yongqun He SAMEA104616168 Stefanie Seltmann, Yongqun He SAMEA104616170 Stefanie Seltmann, Yongqun He SAMEA104616176 Stefanie Seltmann, Yongqun He SAMEA104616178 Stefanie Seltmann, Yongqun He SAMEA104616180 Stefanie Seltmann, Yongqun He SAMEA104616184 Stefanie Seltmann, Yongqun He SAMEA104616186 Stefanie Seltmann, Yongqun He SAMEA104616188 Stefanie Seltmann, Yongqun He SAMEA104617260 Stefanie Seltmann, Yongqun He SAMEA104618139 Stefanie Seltmann, Yongqun He SAMEA104618141 Stefanie Seltmann, Yongqun He SAMEA104618388 Stefanie Seltmann, Yongqun He SAMEA104618766 Stefanie Seltmann, Yongqun He SAMEA104618961 Stefanie Seltmann, Yongqun He SAMEA104618963 Stefanie Seltmann, Yongqun He SAMEA104619381 Stefanie Seltmann, Yongqun He SAMEA104619828 Stefanie Seltmann, Yongqun He SAMEA104619829 Stefanie Seltmann, Yongqun He SAMEA104620316 Stefanie Seltmann, Yongqun He SAMEA104620497 Stefanie Seltmann, Yongqun He SAMEA104620499 Stefanie Seltmann, Yongqun He SAMEA104620633 Stefanie Seltmann, Yongqun He SAMEA104620641 Stefanie Seltmann, Yongqun He SAMEA104620643 Stefanie Seltmann, Yongqun He SAMEA104620645 Stefanie Seltmann, Yongqun He SAMEA104620647 Stefanie Seltmann, Yongqun He SAMEA104620649 Stefanie Seltmann, Yongqun He SAMEA104620651 Stefanie Seltmann, Yongqun He SAMEA104620657 Stefanie Seltmann, Yongqun He SAMEA104620659 Stefanie Seltmann, Yongqun He SAMEA104620663 Stefanie Seltmann, Yongqun He SAMEA104620685 Stefanie Seltmann, Yongqun He SAMEA104620687 Stefanie Seltmann, Yongqun He SAMEA104620689 Stefanie Seltmann, Yongqun He SAMEA104620691 Stefanie Seltmann, Yongqun He SAMEA104620693 Stefanie Seltmann, Yongqun He SAMEA104620703 Stefanie Seltmann, Yongqun He SAMEA104620707 Stefanie Seltmann, Yongqun He SAMEA104620713 Stefanie Seltmann, Yongqun He SAMEA104620715 Stefanie Seltmann, Yongqun He SAMEA104620768 Stefanie Seltmann, Yongqun He SAMEA104620769 Stefanie Seltmann, Yongqun He SAMEA104620771 Stefanie Seltmann, Yongqun He SAMEA104620782 Stefanie Seltmann, Yongqun He SAMEA104620784 Stefanie Seltmann, Yongqun He SAMEA104620788 Stefanie Seltmann, Yongqun He SAMEA104620791 Stefanie Seltmann, Yongqun He SAMEA104621352 Stefanie Seltmann, Yongqun He SAMEA104622927 Stefanie Seltmann, Yongqun He SAMEA104626279 Stefanie Seltmann, Yongqun He SAMEA104626353 Stefanie Seltmann, Yongqun He SAMEA104626791 Stefanie Seltmann, Yongqun He SAMEA104626793 Stefanie Seltmann, Yongqun He SAMEA104627893 Stefanie Seltmann, Yongqun He SAMEA104627895 Stefanie Seltmann, Yongqun He SAMEA104627956 Stefanie Seltmann, Yongqun He SAMEA104627958 Stefanie Seltmann, Yongqun He SAMEA104627960 Stefanie Seltmann, Yongqun He SAMEA104627962 Stefanie Seltmann, Yongqun He SAMEA104627964 Stefanie Seltmann, Yongqun He SAMEA104627966 Stefanie Seltmann, Yongqun He SAMEA104627968 Stefanie Seltmann, Yongqun He SAMEA104627970 Stefanie Seltmann, Yongqun He SAMEA104627972 Stefanie Seltmann, Yongqun He SAMEA104627974 Stefanie Seltmann, Yongqun He SAMEA104627976 Stefanie Seltmann, Yongqun He SAMEA104627978 Stefanie Seltmann, Yongqun He SAMEA104628036 Stefanie Seltmann, Yongqun He SAMEA104628037 Stefanie Seltmann, Yongqun He SAMEA104628039 Stefanie Seltmann, Yongqun He SAMEA104628041 Stefanie Seltmann, Yongqun He SAMEA1080719 Stefanie Seltmann, Yongqun He SAMEA1080720 Stefanie Seltmann, Yongqun He SAMEA1661708 Stefanie Seltmann, Yongqun He SAMEA17470168 Stefanie Seltmann, Yongqun He SAMEA17620168 Stefanie Seltmann, Yongqun He SAMEA17623168 Stefanie Seltmann, Yongqun He SAMEA17625418 Stefanie Seltmann, Yongqun He SAMEA17628418 Stefanie Seltmann, Yongqun He SAMEA17629918 Stefanie Seltmann, Yongqun He SAMEA17631418 Stefanie Seltmann, Yongqun He SAMEA17634418 Stefanie Seltmann, Yongqun He SAMEA17637418 Stefanie Seltmann, Yongqun He SAMEA2335023 Stefanie Seltmann, Yongqun He SAMEA2397795 Stefanie Seltmann, Yongqun He SAMEA2397804 Stefanie Seltmann, Yongqun He SAMEA2397805 Stefanie Seltmann, Yongqun He SAMEA2397810 Stefanie Seltmann, Yongqun He SAMEA2397814 Stefanie Seltmann, Yongqun He SAMEA2397820 Stefanie Seltmann, Yongqun He SAMEA2397821 Stefanie Seltmann, Yongqun He SAMEA2397830 Stefanie Seltmann, Yongqun He SAMEA2397852 Stefanie Seltmann, Yongqun He SAMEA2397855 Stefanie Seltmann, Yongqun He SAMEA2397863 Stefanie Seltmann, Yongqun He SAMEA2397865 Stefanie Seltmann, Yongqun He SAMEA2397879 Stefanie Seltmann, Yongqun He SAMEA2397886 Stefanie Seltmann, Yongqun He SAMEA2397891 Stefanie Seltmann, Yongqun He SAMEA2397893 Stefanie Seltmann, Yongqun He SAMEA2397908 Stefanie Seltmann, Yongqun He SAMEA2397923 Stefanie Seltmann, Yongqun He SAMEA2397926 Stefanie Seltmann, Yongqun He SAMEA2397928 Stefanie Seltmann, Yongqun He SAMEA2397938 Stefanie Seltmann, Yongqun He SAMEA2397939 Stefanie Seltmann, Yongqun He SAMEA2397940 Stefanie Seltmann, Yongqun He SAMEA2397941 Stefanie Seltmann, Yongqun He SAMEA2397943 Stefanie Seltmann, Yongqun He SAMEA2397952 Stefanie Seltmann, Yongqun He SAMEA2397964 Stefanie Seltmann, Yongqun He SAMEA2397969 Stefanie Seltmann, Yongqun He SAMEA2397971 Stefanie Seltmann, Yongqun He SAMEA2397981 Stefanie Seltmann, Yongqun He SAMEA2397995 Stefanie Seltmann, Yongqun He SAMEA2397997 Stefanie Seltmann, Yongqun He SAMEA2398014 Stefanie Seltmann, Yongqun He SAMEA2398019 Stefanie Seltmann, Yongqun He SAMEA2398030 Stefanie Seltmann, Yongqun He SAMEA2398036 Stefanie Seltmann, Yongqun He SAMEA2398076 Stefanie Seltmann, Yongqun He SAMEA2398079 Stefanie Seltmann, Yongqun He SAMEA2398092 Stefanie Seltmann, Yongqun He SAMEA2398093 Stefanie Seltmann, Yongqun He SAMEA2398104 Stefanie Seltmann, Yongqun He SAMEA2398105 Stefanie Seltmann, Yongqun He SAMEA2398138 Stefanie Seltmann, Yongqun He SAMEA2398140 Stefanie Seltmann, Yongqun He SAMEA2398142 Stefanie Seltmann, Yongqun He SAMEA2398162 Stefanie Seltmann, Yongqun He SAMEA2398175 Stefanie Seltmann, Yongqun He SAMEA2398189 Stefanie Seltmann, Yongqun He SAMEA2398192 Stefanie Seltmann, Yongqun He SAMEA2398193 Stefanie Seltmann, Yongqun He SAMEA2398208 Stefanie Seltmann, Yongqun He SAMEA2398216 Stefanie Seltmann, Yongqun He SAMEA2398221 Stefanie Seltmann, Yongqun He SAMEA2398241 Stefanie Seltmann, Yongqun He SAMEA2398254 Stefanie Seltmann, Yongqun He SAMEA2398259 Stefanie Seltmann, Yongqun He SAMEA2398273 Stefanie Seltmann, Yongqun He SAMEA2398275 Stefanie Seltmann, Yongqun He SAMEA2398288 Stefanie Seltmann, Yongqun He SAMEA2398290 Stefanie Seltmann, Yongqun He SAMEA2398301 Stefanie Seltmann, Yongqun He SAMEA2398311 Stefanie Seltmann, Yongqun He SAMEA2398326 Stefanie Seltmann, Yongqun He SAMEA2398337 Stefanie Seltmann, Yongqun He SAMEA2398351 Stefanie Seltmann, Yongqun He SAMEA2398363 Stefanie Seltmann, Yongqun He SAMEA2398370 Stefanie Seltmann, Yongqun He SAMEA2398375 Stefanie Seltmann, Yongqun He SAMEA2398392 Stefanie Seltmann, Yongqun He SAMEA2398402 Stefanie Seltmann, Yongqun He SAMEA2398406 Stefanie Seltmann, Yongqun He SAMEA2398409 Stefanie Seltmann, Yongqun He SAMEA2398431 Stefanie Seltmann, Yongqun He SAMEA2398437 Stefanie Seltmann, Yongqun He SAMEA2398438 Stefanie Seltmann, Yongqun He SAMEA2398439 Stefanie Seltmann, Yongqun He SAMEA2398453 Stefanie Seltmann, Yongqun He SAMEA2398454 Stefanie Seltmann, Yongqun He SAMEA2398464 Stefanie Seltmann, Yongqun He SAMEA2398474 Stefanie Seltmann, Yongqun He SAMEA2398480 Stefanie Seltmann, Yongqun He SAMEA2398488 Stefanie Seltmann, Yongqun He SAMEA2398489 Stefanie Seltmann, Yongqun He SAMEA2398506 Stefanie Seltmann, Yongqun He SAMEA2398527 Stefanie Seltmann, Yongqun He SAMEA2398529 Stefanie Seltmann, Yongqun He SAMEA2398536 Stefanie Seltmann, Yongqun He SAMEA2398540 Stefanie Seltmann, Yongqun He SAMEA2398548 Stefanie Seltmann, Yongqun He SAMEA2398550 Stefanie Seltmann, Yongqun He SAMEA2398551 Stefanie Seltmann, Yongqun He SAMEA2398556 Stefanie Seltmann, Yongqun He SAMEA2398564 Stefanie Seltmann, Yongqun He SAMEA2398565 Stefanie Seltmann, Yongqun He SAMEA2398572 Stefanie Seltmann, Yongqun He SAMEA2398585 Stefanie Seltmann, Yongqun He SAMEA2398589 Stefanie Seltmann, Yongqun He SAMEA2398592 Stefanie Seltmann, Yongqun He SAMEA2398595 Stefanie Seltmann, Yongqun He SAMEA2398604 Stefanie Seltmann, Yongqun He SAMEA2398605 Stefanie Seltmann, Yongqun He SAMEA2398607 Stefanie Seltmann, Yongqun He SAMEA2398611 Stefanie Seltmann, Yongqun He SAMEA2398621 Stefanie Seltmann, Yongqun He SAMEA2398624 Stefanie Seltmann, Yongqun He SAMEA2398630 Stefanie Seltmann, Yongqun He SAMEA2398642 Stefanie Seltmann, Yongqun He SAMEA2398645 Stefanie Seltmann, Yongqun He SAMEA2398646 Stefanie Seltmann, Yongqun He SAMEA2398654 Stefanie Seltmann, Yongqun He SAMEA2398674 Stefanie Seltmann, Yongqun He SAMEA2398675 Stefanie Seltmann, Yongqun He SAMEA2398697 Stefanie Seltmann, Yongqun He SAMEA2398720 Stefanie Seltmann, Yongqun He SAMEA2398721 Stefanie Seltmann, Yongqun He SAMEA2398736 Stefanie Seltmann, Yongqun He SAMEA2398744 Stefanie Seltmann, Yongqun He SAMEA2398759 Stefanie Seltmann, Yongqun He SAMEA2398765 Stefanie Seltmann, Yongqun He SAMEA2398769 Stefanie Seltmann, Yongqun He SAMEA2398775 Stefanie Seltmann, Yongqun He SAMEA2398777 Stefanie Seltmann, Yongqun He SAMEA2398781 Stefanie Seltmann, Yongqun He SAMEA2398787 Stefanie Seltmann, Yongqun He SAMEA2398790 Stefanie Seltmann, Yongqun He SAMEA2398810 Stefanie Seltmann, Yongqun He SAMEA2398814 Stefanie Seltmann, Yongqun He SAMEA2398815 Stefanie Seltmann, Yongqun He SAMEA2398825 Stefanie Seltmann, Yongqun He SAMEA2398835 Stefanie Seltmann, Yongqun He SAMEA2398839 Stefanie Seltmann, Yongqun He SAMEA2398840 Stefanie Seltmann, Yongqun He SAMEA2398852 Stefanie Seltmann, Yongqun He SAMEA2398854 Stefanie Seltmann, Yongqun He SAMEA2398860 Stefanie Seltmann, Yongqun He SAMEA2398874 Stefanie Seltmann, Yongqun He SAMEA2398876 Stefanie Seltmann, Yongqun He SAMEA2398882 Stefanie Seltmann, Yongqun He SAMEA2398888 Stefanie Seltmann, Yongqun He SAMEA2398893 Stefanie Seltmann, Yongqun He SAMEA2398902 Stefanie Seltmann, Yongqun He SAMEA2398906 Stefanie Seltmann, Yongqun He SAMEA2398910 Stefanie Seltmann, Yongqun He SAMEA2398911 Stefanie Seltmann, Yongqun He SAMEA2398924 Stefanie Seltmann, Yongqun He SAMEA2398937 Stefanie Seltmann, Yongqun He SAMEA2398951 Stefanie Seltmann, Yongqun He SAMEA2398959 Stefanie Seltmann, Yongqun He SAMEA2398960 Stefanie Seltmann, Yongqun He SAMEA2398961 Stefanie Seltmann, Yongqun He SAMEA2398962 Stefanie Seltmann, Yongqun He SAMEA2398972 Stefanie Seltmann, Yongqun He SAMEA2398975 Stefanie Seltmann, Yongqun He SAMEA2398993 Stefanie Seltmann, Yongqun He SAMEA2398994 Stefanie Seltmann, Yongqun He SAMEA2398997 Stefanie Seltmann, Yongqun He SAMEA2399007 Stefanie Seltmann, Yongqun He SAMEA2399013 Stefanie Seltmann, Yongqun He SAMEA2399018 Stefanie Seltmann, Yongqun He SAMEA2399020 Stefanie Seltmann, Yongqun He SAMEA2399022 Stefanie Seltmann, Yongqun He SAMEA2399030 Stefanie Seltmann, Yongqun He SAMEA2399041 Stefanie Seltmann, Yongqun He SAMEA2399046 Stefanie Seltmann, Yongqun He SAMEA2399048 Stefanie Seltmann, Yongqun He SAMEA2399050 Stefanie Seltmann, Yongqun He SAMEA2399052 Stefanie Seltmann, Yongqun He SAMEA2399069 Stefanie Seltmann, Yongqun He SAMEA2399082 Stefanie Seltmann, Yongqun He SAMEA2399101 Stefanie Seltmann, Yongqun He SAMEA2399102 Stefanie Seltmann, Yongqun He SAMEA2399103 Stefanie Seltmann, Yongqun He SAMEA2399109 Stefanie Seltmann, Yongqun He SAMEA2399122 Stefanie Seltmann, Yongqun He SAMEA2399129 Stefanie Seltmann, Yongqun He SAMEA2399135 Stefanie Seltmann, Yongqun He SAMEA2399138 Stefanie Seltmann, Yongqun He SAMEA2399169 Stefanie Seltmann, Yongqun He SAMEA2399174 Stefanie Seltmann, Yongqun He SAMEA2399181 Stefanie Seltmann, Yongqun He SAMEA2399191 Stefanie Seltmann, Yongqun He SAMEA2399198 Stefanie Seltmann, Yongqun He SAMEA2399202 Stefanie Seltmann, Yongqun He SAMEA2399206 Stefanie Seltmann, Yongqun He SAMEA2399207 Stefanie Seltmann, Yongqun He SAMEA2399211 Stefanie Seltmann, Yongqun He SAMEA2399225 Stefanie Seltmann, Yongqun He SAMEA2399235 Stefanie Seltmann, Yongqun He SAMEA2399246 Stefanie Seltmann, Yongqun He SAMEA2399253 Stefanie Seltmann, Yongqun He SAMEA2399254 Stefanie Seltmann, Yongqun He SAMEA2399255 Stefanie Seltmann, Yongqun He SAMEA2399272 Stefanie Seltmann, Yongqun He SAMEA2399274 Stefanie Seltmann, Yongqun He SAMEA2399466 Stefanie Seltmann, Yongqun He SAMEA2399961 Stefanie Seltmann, Yongqun He SAMEA2399962 Stefanie Seltmann, Yongqun He SAMEA2400641 Stefanie Seltmann, Yongqun He SAMEA2418245 Stefanie Seltmann, Yongqun He SAMEA2422403 Stefanie Seltmann, Yongqun He SAMEA2425047 Stefanie Seltmann, Yongqun He SAMEA2425049 Stefanie Seltmann, Yongqun He SAMEA2434169 Stefanie Seltmann, Yongqun He SAMEA2434172 Stefanie Seltmann, Yongqun He SAMEA2437414 Stefanie Seltmann, Yongqun He SAMEA2438675 Stefanie Seltmann, Yongqun He SAMEA2444537 Stefanie Seltmann, Yongqun He SAMEA2444538 Stefanie Seltmann, Yongqun He SAMEA2444542 Stefanie Seltmann, Yongqun He SAMEA2444543 Stefanie Seltmann, Yongqun He SAMEA2444545 Stefanie Seltmann, Yongqun He SAMEA2464777 Stefanie Seltmann, Yongqun He SAMEA2464778 Stefanie Seltmann, Yongqun He SAMEA2464780 Stefanie Seltmann, Yongqun He SAMEA2464781 Stefanie Seltmann, Yongqun He SAMEA2464782 Stefanie Seltmann, Yongqun He SAMEA2464783 Stefanie Seltmann, Yongqun He SAMEA2464784 Stefanie Seltmann, Yongqun He SAMEA2464787 Stefanie Seltmann, Yongqun He SAMEA2464805 Stefanie Seltmann, Yongqun He SAMEA2464817 Stefanie Seltmann, Yongqun He SAMEA2464823 Stefanie Seltmann, Yongqun He SAMEA2464824 Stefanie Seltmann, Yongqun He SAMEA2464827 Stefanie Seltmann, Yongqun He SAMEA2467860 Stefanie Seltmann, Yongqun He SAMEA2472099 Stefanie Seltmann, Yongqun He SAMEA2472100 Stefanie Seltmann, Yongqun He SAMEA2474448 Stefanie Seltmann, Yongqun He SAMEA2474453 Stefanie Seltmann, Yongqun He SAMEA2474460 Stefanie Seltmann, Yongqun He SAMEA2482374 Stefanie Seltmann, Yongqun He SAMEA2482376 Stefanie Seltmann, Yongqun He SAMEA2482379 Stefanie Seltmann, Yongqun He SAMEA2482380 Stefanie Seltmann, Yongqun He SAMEA2482381 Stefanie Seltmann, Yongqun He SAMEA2482383 Stefanie Seltmann, Yongqun He SAMEA2482384 Stefanie Seltmann, Yongqun He SAMEA2482386 Stefanie Seltmann, Yongqun He SAMEA2482387 Stefanie Seltmann, Yongqun He SAMEA2482390 Stefanie Seltmann, Yongqun He SAMEA2482395 Stefanie Seltmann, Yongqun He SAMEA2482396 Stefanie Seltmann, Yongqun He SAMEA2493813 Stefanie Seltmann, Yongqun He SAMEA2517314 Stefanie Seltmann, Yongqun He SAMEA2517315 Stefanie Seltmann, Yongqun He SAMEA2517317 Stefanie Seltmann, Yongqun He SAMEA2517318 Stefanie Seltmann, Yongqun He SAMEA2517319 Stefanie Seltmann, Yongqun He SAMEA2519547 Stefanie Seltmann, Yongqun He SAMEA2519548 Stefanie Seltmann, Yongqun He SAMEA2519553 Stefanie Seltmann, Yongqun He SAMEA2531392 Stefanie Seltmann, Yongqun He SAMEA2531393 Stefanie Seltmann, Yongqun He SAMEA2531400 Stefanie Seltmann, Yongqun He SAMEA2531401 Stefanie Seltmann, Yongqun He SAMEA2533334 Stefanie Seltmann, Yongqun He SAMEA2533335 Stefanie Seltmann, Yongqun He SAMEA2538856 Stefanie Seltmann, Yongqun He SAMEA2538858 Stefanie Seltmann, Yongqun He SAMEA2547611 Stefanie Seltmann, Yongqun He SAMEA2547636 Stefanie Seltmann, Yongqun He SAMEA2547643 Stefanie Seltmann, Yongqun He SAMEA2547892 Stefanie Seltmann, Yongqun He SAMEA2547897 Stefanie Seltmann, Yongqun He SAMEA2548019 Stefanie Seltmann, Yongqun He SAMEA2548021 Stefanie Seltmann, Yongqun He SAMEA2548025 Stefanie Seltmann, Yongqun He SAMEA2548026 Stefanie Seltmann, Yongqun He SAMEA2548033 Stefanie Seltmann, Yongqun He SAMEA2548036 Stefanie Seltmann, Yongqun He SAMEA2554407 Stefanie Seltmann, Yongqun He SAMEA2555014 Stefanie Seltmann, Yongqun He SAMEA2555016 Stefanie Seltmann, Yongqun He SAMEA2567344 Stefanie Seltmann, Yongqun He SAMEA2567346 Stefanie Seltmann, Yongqun He SAMEA2570422 Stefanie Seltmann, Yongqun He SAMEA2570430 Stefanie Seltmann, Yongqun He SAMEA2586982 Stefanie Seltmann, Yongqun He SAMEA2586988 Stefanie Seltmann, Yongqun He SAMEA2586989 Stefanie Seltmann, Yongqun He SAMEA2586990 Stefanie Seltmann, Yongqun He SAMEA2590619 Stefanie Seltmann, Yongqun He SAMEA2590892 Stefanie Seltmann, Yongqun He SAMEA2590985 Stefanie Seltmann, Yongqun He SAMEA2591001 Stefanie Seltmann, Yongqun He SAMEA2593195 Stefanie Seltmann, Yongqun He SAMEA2593201 Stefanie Seltmann, Yongqun He SAMEA2595429 Stefanie Seltmann, Yongqun He SAMEA2595430 Stefanie Seltmann, Yongqun He SAMEA2595433 Stefanie Seltmann, Yongqun He SAMEA2595435 Stefanie Seltmann, Yongqun He SAMEA2595436 Stefanie Seltmann, Yongqun He SAMEA2602903 Stefanie Seltmann, Yongqun He SAMEA2604126 Stefanie Seltmann, Yongqun He SAMEA2612452 Stefanie Seltmann, Yongqun He SAMEA2612455 Stefanie Seltmann, Yongqun He SAMEA2612460 Stefanie Seltmann, Yongqun He SAMEA2612463 Stefanie Seltmann, Yongqun He SAMEA2612466 Stefanie Seltmann, Yongqun He SAMEA2612476 Stefanie Seltmann, Yongqun He SAMEA2613903 Stefanie Seltmann, Yongqun He SAMEA2613910 Stefanie Seltmann, Yongqun He SAMEA2613913 Stefanie Seltmann, Yongqun He SAMEA2613916 Stefanie Seltmann, Yongqun He SAMEA2614020 Stefanie Seltmann, Yongqun He SAMEA2614021 Stefanie Seltmann, Yongqun He SAMEA2619286 Stefanie Seltmann, Yongqun He SAMEA2619290 Stefanie Seltmann, Yongqun He SAMEA2625594 Stefanie Seltmann, Yongqun He SAMEA2629494 Stefanie Seltmann, Yongqun He SAMEA2629512 Stefanie Seltmann, Yongqun He SAMEA2629548 Stefanie Seltmann, Yongqun He SAMEA2629629 Stefanie Seltmann, Yongqun He SAMEA2629633 Stefanie Seltmann, Yongqun He SAMEA2632927 Stefanie Seltmann, Yongqun He SAMEA2645808 Stefanie Seltmann, Yongqun He SAMEA2645812 Stefanie Seltmann, Yongqun He SAMEA2649531 Stefanie Seltmann, Yongqun He SAMEA2658091 Stefanie Seltmann, Yongqun He SAMEA2658100 Stefanie Seltmann, Yongqun He SAMEA2658101 Stefanie Seltmann, Yongqun He SAMEA2658103 Stefanie Seltmann, Yongqun He SAMEA2658104 Stefanie Seltmann, Yongqun He SAMEA2661680 Stefanie Seltmann, Yongqun He SAMEA2663603 Stefanie Seltmann, Yongqun He SAMEA2663611 Stefanie Seltmann, Yongqun He SAMEA2663613 Stefanie Seltmann, Yongqun He SAMEA2663616 Stefanie Seltmann, Yongqun He SAMEA2663619 Stefanie Seltmann, Yongqun He SAMEA2663620 Stefanie Seltmann, Yongqun He SAMEA2663623 Stefanie Seltmann, Yongqun He SAMEA2663626 Stefanie Seltmann, Yongqun He SAMEA2663630 Stefanie Seltmann, Yongqun He SAMEA2663638 Stefanie Seltmann, Yongqun He SAMEA2675455 Stefanie Seltmann, Yongqun He SAMEA2676423 Stefanie Seltmann, Yongqun He SAMEA2689593 Stefanie Seltmann, Yongqun He SAMEA2724752 Stefanie Seltmann, Yongqun He SAMEA2724754 Stefanie Seltmann, Yongqun He SAMEA2743224 Stefanie Seltmann, Yongqun He SAMEA2743227 Stefanie Seltmann, Yongqun He SAMEA2765382 Stefanie Seltmann, Yongqun He SAMEA2765383 Stefanie Seltmann, Yongqun He SAMEA2769873 Stefanie Seltmann, Yongqun He SAMEA2771235 Stefanie Seltmann, Yongqun He SAMEA2774627 Stefanie Seltmann, Yongqun He SAMEA2784223 Stefanie Seltmann, Yongqun He SAMEA2784227 Stefanie Seltmann, Yongqun He SAMEA2784228 Stefanie Seltmann, Yongqun He SAMEA2784229 Stefanie Seltmann, Yongqun He SAMEA2784660 Stefanie Seltmann, Yongqun He SAMEA2784670 Stefanie Seltmann, Yongqun He SAMEA2785482 Stefanie Seltmann, Yongqun He SAMEA2785483 Stefanie Seltmann, Yongqun He SAMEA2785488 Stefanie Seltmann, Yongqun He SAMEA2785501 Stefanie Seltmann, Yongqun He SAMEA2794303 Stefanie Seltmann, Yongqun He SAMEA2796148 Stefanie Seltmann, Yongqun He SAMEA2796333 Stefanie Seltmann, Yongqun He SAMEA2811562 Stefanie Seltmann, Yongqun He SAMEA2821481 Stefanie Seltmann, Yongqun He SAMEA2821483 Stefanie Seltmann, Yongqun He SAMEA2821685 Stefanie Seltmann, Yongqun He SAMEA2821688 Stefanie Seltmann, Yongqun He SAMEA2825552 Stefanie Seltmann, Yongqun He SAMEA2825825 Stefanie Seltmann, Yongqun He SAMEA2825874 Stefanie Seltmann, Yongqun He SAMEA2825966 Stefanie Seltmann, Yongqun He SAMEA2827510 Stefanie Seltmann, Yongqun He SAMEA2845304 Stefanie Seltmann, Yongqun He SAMEA3099617 Stefanie Seltmann, Yongqun He SAMEA3105043 Stefanie Seltmann, Yongqun He SAMEA3105049 Stefanie Seltmann, Yongqun He SAMEA3105780 Stefanie Seltmann, Yongqun He SAMEA3105813 Stefanie Seltmann, Yongqun He SAMEA3105889 Stefanie Seltmann, Yongqun He SAMEA3105960 Stefanie Seltmann, Yongqun He SAMEA3106020 Stefanie Seltmann, Yongqun He SAMEA3106369 Stefanie Seltmann, Yongqun He SAMEA3106370 Stefanie Seltmann, Yongqun He SAMEA3107600 Stefanie Seltmann, Yongqun He SAMEA3107605 Stefanie Seltmann, Yongqun He SAMEA3107606 Stefanie Seltmann, Yongqun He SAMEA3109703 Stefanie Seltmann, Yongqun He SAMEA3111106 Stefanie Seltmann, Yongqun He SAMEA3113463 Stefanie Seltmann, Yongqun He SAMEA3113935 Stefanie Seltmann, Yongqun He SAMEA3113942 Stefanie Seltmann, Yongqun He SAMEA3120528 Stefanie Seltmann, Yongqun He SAMEA3142086 Stefanie Seltmann, Yongqun He SAMEA3142155 Stefanie Seltmann, Yongqun He SAMEA3174344 Stefanie Seltmann, Yongqun He SAMEA3174431 Stefanie Seltmann, Yongqun He SAMEA3174486 Stefanie Seltmann, Yongqun He SAMEA3174526 Stefanie Seltmann, Yongqun He SAMEA3180220 Stefanie Seltmann, Yongqun He SAMEA3180222 Stefanie Seltmann, Yongqun He SAMEA3180224 Stefanie Seltmann, Yongqun He SAMEA3180226 Stefanie Seltmann, Yongqun He SAMEA3182891 Stefanie Seltmann, Yongqun He SAMEA3182893 Stefanie Seltmann, Yongqun He SAMEA3182894 Stefanie Seltmann, Yongqun He SAMEA3206409 Stefanie Seltmann, Yongqun He SAMEA3206410 Stefanie Seltmann, Yongqun He SAMEA3206411 Stefanie Seltmann, Yongqun He SAMEA3206416 Stefanie Seltmann, Yongqun He SAMEA3207610 Stefanie Seltmann, Yongqun He SAMEA3207612 Stefanie Seltmann, Yongqun He SAMEA3207616 Stefanie Seltmann, Yongqun He SAMEA3208492 Stefanie Seltmann, Yongqun He SAMEA3208493 Stefanie Seltmann, Yongqun He SAMEA3212982 Stefanie Seltmann, Yongqun He SAMEA3215181 Stefanie Seltmann, Yongqun He SAMEA3215182 Stefanie Seltmann, Yongqun He SAMEA3215184 Stefanie Seltmann, Yongqun He SAMEA3216834 Stefanie Seltmann, Yongqun He SAMEA3216954 Stefanie Seltmann, Yongqun He SAMEA3216956 Stefanie Seltmann, Yongqun He SAMEA3216958 Stefanie Seltmann, Yongqun He SAMEA3220401 Stefanie Seltmann, Yongqun He SAMEA3220404 Stefanie Seltmann, Yongqun He SAMEA3221085 Stefanie Seltmann, Yongqun He SAMEA3232160 Stefanie Seltmann, Yongqun He SAMEA3249307 Stefanie Seltmann, Yongqun He SAMEA3249312 Stefanie Seltmann, Yongqun He SAMEA3249666 Stefanie Seltmann, Yongqun He SAMEA3251277 Stefanie Seltmann, Yongqun He SAMEA3257557 Stefanie Seltmann, Yongqun He SAMEA3257658 Stefanie Seltmann, Yongqun He SAMEA3257659 Stefanie Seltmann, Yongqun He SAMEA3275858 Stefanie Seltmann, Yongqun He SAMEA3275922 Stefanie Seltmann, Yongqun He SAMEA3275956 Stefanie Seltmann, Yongqun He SAMEA3302933 Stefanie Seltmann, Yongqun He SAMEA3302974 Stefanie Seltmann, Yongqun He SAMEA3303031 Stefanie Seltmann, Yongqun He SAMEA3303077 Stefanie Seltmann, Yongqun He SAMEA3303136 Stefanie Seltmann, Yongqun He SAMEA3303187 Stefanie Seltmann, Yongqun He SAMEA3303248 Stefanie Seltmann, Yongqun He SAMEA3303305 Stefanie Seltmann, Yongqun He SAMEA3319991 Stefanie Seltmann, Yongqun He SAMEA3333373 Stefanie Seltmann, Yongqun He SAMEA3368198 Stefanie Seltmann, Yongqun He SAMEA3477718 Stefanie Seltmann, Yongqun He SAMEA3735552 Stefanie Seltmann, Yongqun He SAMEA3753584 Stefanie Seltmann, Yongqun He SAMEA3961551 Stefanie Seltmann, Yongqun He SAMEA3961579 Stefanie Seltmann, Yongqun He SAMEA3962448 Stefanie Seltmann, Yongqun He SAMEA3964276 Stefanie Seltmann, Yongqun He SAMEA4084801 Stefanie Seltmann, Yongqun He SAMEA4085220 Stefanie Seltmann, Yongqun He SAMEA4091843 Stefanie Seltmann, Yongqun He SAMEA4091958 Stefanie Seltmann, Yongqun He SAMEA4092787 Stefanie Seltmann, Yongqun He SAMEA4092876 Stefanie Seltmann, Yongqun He SAMEA4096476 Stefanie Seltmann, Yongqun He SAMEA4096551 Stefanie Seltmann, Yongqun He SAMEA4096552 Stefanie Seltmann, Yongqun He SAMEA4096553 Stefanie Seltmann, Yongqun He SAMEA4096557 Stefanie Seltmann, Yongqun He SAMEA4096558 Stefanie Seltmann, Yongqun He SAMEA4096559 Stefanie Seltmann, Yongqun He SAMEA4096962 Stefanie Seltmann, Yongqun He SAMEA4096963 Stefanie Seltmann, Yongqun He SAMEA4096965 Stefanie Seltmann, Yongqun He SAMEA4096969 Stefanie Seltmann, Yongqun He SAMEA4309032 Stefanie Seltmann, Yongqun He SAMEA4309033 Stefanie Seltmann, Yongqun He SAMEA4339659 Stefanie Seltmann, Yongqun He SAMEA4339709 Stefanie Seltmann, Yongqun He SAMEA4340582 Stefanie Seltmann, Yongqun He SAMEA4341880 Stefanie Seltmann, Yongqun He SAMEA4341896 Stefanie Seltmann, Yongqun He SAMEA4341901 Stefanie Seltmann, Yongqun He SAMEA4341903 Stefanie Seltmann, Yongqun He SAMEA4342127 Stefanie Seltmann, Yongqun He SAMEA4342132 Stefanie Seltmann, Yongqun He SAMEA4342497 Stefanie Seltmann, Yongqun He SAMEA4342565 Stefanie Seltmann, Yongqun He SAMEA4342626 Stefanie Seltmann, Yongqun He SAMEA4342657 Stefanie Seltmann, Yongqun He SAMEA4343055 Stefanie Seltmann, Yongqun He SAMEA4343577 Stefanie Seltmann, Yongqun He SAMEA4343583 Stefanie Seltmann, Yongqun He SAMEA4343584 Stefanie Seltmann, Yongqun He SAMEA4343604 Stefanie Seltmann, Yongqun He SAMEA4446736 Stefanie Seltmann, Yongqun He SAMEA4446977 Stefanie Seltmann, Yongqun He SAMEA4447047 Stefanie Seltmann, Yongqun He SAMEA4447176 Stefanie Seltmann, Yongqun He SAMEA4447407 Stefanie Seltmann, Yongqun He SAMEA4447434 Stefanie Seltmann, Yongqun He SAMEA4447600 Stefanie Seltmann, Yongqun He SAMEA4447906 Stefanie Seltmann, Yongqun He SAMEA4448117 Stefanie Seltmann, Yongqun He SAMEA4448501 Stefanie Seltmann, Yongqun He SAMEA4448503 Stefanie Seltmann, Yongqun He SAMEA4449143 Stefanie Seltmann, Yongqun He SAMEA4449146 Stefanie Seltmann, Yongqun He SAMEA4449148 Stefanie Seltmann, Yongqun He SAMEA4451104 Stefanie Seltmann, Yongqun He SAMEA4451105 Stefanie Seltmann, Yongqun He SAMEA4451166 Stefanie Seltmann, Yongqun He SAMEA4451662 Stefanie Seltmann, Yongqun He SAMEA4451664 Stefanie Seltmann, Yongqun He SAMEA4451666 Stefanie Seltmann, Yongqun He SAMEA4451668 Stefanie Seltmann, Yongqun He SAMEA4451670 Stefanie Seltmann, Yongqun He SAMEA4451672 Stefanie Seltmann, Yongqun He SAMEA4452341 Stefanie Seltmann, Yongqun He SAMEA4452343 Stefanie Seltmann, Yongqun He SAMEA4453483 Stefanie Seltmann, Yongqun He SAMEA4453752 Stefanie Seltmann, Yongqun He SAMEA4453764 Stefanie Seltmann, Yongqun He SAMEA4453765 Stefanie Seltmann, Yongqun He SAMEA4453833 Stefanie Seltmann, Yongqun He SAMEA4453834 Stefanie Seltmann, Yongqun He SAMEA4453898 Stefanie Seltmann, Yongqun He SAMEA4453967 Stefanie Seltmann, Yongqun He SAMEA4453973 Stefanie Seltmann, Yongqun He SAMEA4453977 Stefanie Seltmann, Yongqun He SAMEA4453983 Stefanie Seltmann, Yongqun He SAMEA4453985 Stefanie Seltmann, Yongqun He SAMEA4453987 Stefanie Seltmann, Yongqun He SAMEA4453997 Stefanie Seltmann, Yongqun He SAMEA4454004 Stefanie Seltmann, Yongqun He SAMEA4454013 Stefanie Seltmann, Yongqun He SAMEA4454015 Stefanie Seltmann, Yongqun He SAMEA4454017 Stefanie Seltmann, Yongqun He SAMEA4454105 Stefanie Seltmann, Yongqun He SAMEA4454108 Stefanie Seltmann, Yongqun He SAMEA4454110 Stefanie Seltmann, Yongqun He SAMEA4454478 Stefanie Seltmann, Yongqun He SAMEA4454945 Stefanie Seltmann, Yongqun He SAMEA4454947 Stefanie Seltmann, Yongqun He SAMEA4454949 Stefanie Seltmann, Yongqun He SAMEA4455496 Stefanie Seltmann, Yongqun He SAMEA4455498 Stefanie Seltmann, Yongqun He SAMEA4455500 Stefanie Seltmann, Yongqun He SAMEA4455502 Stefanie Seltmann, Yongqun He SAMEA4455504 Stefanie Seltmann, Yongqun He SAMEA4455506 Stefanie Seltmann, Yongqun He SAMEA4455508 Stefanie Seltmann, Yongqun He SAMEA4455860 Stefanie Seltmann, Yongqun He SAMEA4455862 Stefanie Seltmann, Yongqun He SAMEA4458266 Stefanie Seltmann, Yongqun He SAMEA4458345 Stefanie Seltmann, Yongqun He SAMEA4458543 Stefanie Seltmann, Yongqun He SAMEA4458548 Stefanie Seltmann, Yongqun He SAMEA4458846 Stefanie Seltmann, Yongqun He SAMEA4458849 Stefanie Seltmann, Yongqun He SAMEA4458851 Stefanie Seltmann, Yongqun He SAMEA4458853 Stefanie Seltmann, Yongqun He SAMEA4459370 Stefanie Seltmann, Yongqun He SAMEA4459374 Stefanie Seltmann, Yongqun He SAMEA4459401 Stefanie Seltmann, Yongqun He SAMEA4459406 Stefanie Seltmann, Yongqun He SAMEA4459410 Stefanie Seltmann, Yongqun He SAMEA4459411 Stefanie Seltmann, Yongqun He SAMEA4459412 Stefanie Seltmann, Yongqun He SAMEA4459415 Stefanie Seltmann, Yongqun He SAMEA4459419 Stefanie Seltmann, Yongqun He SAMEA4459425 Stefanie Seltmann, Yongqun He SAMEA4459428 Stefanie Seltmann, Yongqun He SAMEA4459431 Stefanie Seltmann, Yongqun He SAMEA4459433 Stefanie Seltmann, Yongqun He SAMEA4459436 Stefanie Seltmann, Yongqun He SAMEA4459437 Stefanie Seltmann, Yongqun He SAMEA4561632 Stefanie Seltmann, Yongqun He SAMEA4562381 Stefanie Seltmann, Yongqun He SAMEA4563386 Stefanie Seltmann, Yongqun He SAMEA4563387 Stefanie Seltmann, Yongqun He SAMEA4563390 Stefanie Seltmann, Yongqun He SAMEA4563392 Stefanie Seltmann, Yongqun He SAMEA4563394 Stefanie Seltmann, Yongqun He SAMEA4564039 Stefanie Seltmann, Yongqun He SAMEA4564040 Stefanie Seltmann, Yongqun He SAMEA4564048 Stefanie Seltmann, Yongqun He SAMEA4564585 Stefanie Seltmann, Yongqun He SAMEA4567586 Stefanie Seltmann, Yongqun He SAMEA4582266 Stefanie Seltmann, Yongqun He SAMEA4583720 Stefanie Seltmann, Yongqun He SAMEA4584076 Stefanie Seltmann, Yongqun He SAMEA4584241 Stefanie Seltmann, Yongqun He SAMEA4584322 Stefanie Seltmann, Yongqun He SAMEA4671418 Stefanie Seltmann, Yongqun He SAMEA4675565 Stefanie Seltmann, Yongqun He SAMEA4675570 Stefanie Seltmann, Yongqun He SAMEA4675623 Stefanie Seltmann, Yongqun He SAMEA4675626 Stefanie Seltmann, Yongqun He SAMEA4675629 Stefanie Seltmann, Yongqun He SAMEA4675696 Stefanie Seltmann, Yongqun He SAMEA4675909 Stefanie Seltmann, Yongqun He SAMEA4702168 Stefanie Seltmann, Yongqun He SAMEA4702918 Stefanie Seltmann, Yongqun He SAMEA4703668 Stefanie Seltmann, Yongqun He SAMEA4760482 Stefanie Seltmann, Yongqun He SAMEA4760628 Stefanie Seltmann, Yongqun He SAMEA4760630 Stefanie Seltmann, Yongqun He SAMEA4760685 Stefanie Seltmann, Yongqun He SAMEA4760690 Stefanie Seltmann, Yongqun He SAMEA4760722 Stefanie Seltmann, Yongqun He SAMEA4760914 Stefanie Seltmann, Yongqun He SAMEA4861682 Stefanie Seltmann, Yongqun He SAMEA4861684 Stefanie Seltmann, Yongqun He SAMEA4861902 Stefanie Seltmann, Yongqun He SAMEA4862233 Stefanie Seltmann, Yongqun He SAMEA4862235 Stefanie Seltmann, Yongqun He SAMEA4862237 Stefanie Seltmann, Yongqun He SAMEA4880778 Stefanie Seltmann, Yongqun He SAMEA4892801 Stefanie Seltmann, Yongqun He SAMEA4892802 Stefanie Seltmann, Yongqun He SAMEA4892803 Stefanie Seltmann, Yongqun He SAMEA4909540 Stefanie Seltmann, Yongqun He SAMEA4909542 Stefanie Seltmann, Yongqun He SAMEA4914697 Stefanie Seltmann, Yongqun He SAMEA4932835 Stefanie Seltmann, Yongqun He SAMEA4932837 Stefanie Seltmann, Yongqun He SAMEA4932839 Stefanie Seltmann, Yongqun He SAMEA4938814 Stefanie Seltmann, Yongqun He SAMEA4984139 Stefanie Seltmann, Yongqun He SAMEA4984142 Stefanie Seltmann, Yongqun He SAMEA4999068 Stefanie Seltmann, Yongqun He SAMEA4999621 Stefanie Seltmann, Yongqun He SAMEA5032583 Stefanie Seltmann, Yongqun He SAMEA5043220 Stefanie Seltmann, Yongqun He SAMEA5044660 Stefanie Seltmann, Yongqun He SAMEA5121563 Stefanie Seltmann, Yongqun He SAMEA5126963 Stefanie Seltmann, Yongqun He SAMEA5126965 Stefanie Seltmann, Yongqun He SAMEA5126967 Stefanie Seltmann, Yongqun He SAMEA5131662 Stefanie Seltmann, Yongqun He SAMEA5131665 Stefanie Seltmann, Yongqun He SAMEA5176968 Stefanie Seltmann, Yongqun He SAMEA5176969 Stefanie Seltmann, Yongqun He SAMEA5176970 Stefanie Seltmann, Yongqun He SAMEA5176971 Stefanie Seltmann, Yongqun He SAMEA5176972 Stefanie Seltmann, Yongqun He SAMEA5176973 Stefanie Seltmann, Yongqun He SAMEA5230332 Stefanie Seltmann, Yongqun He SAMEA5230378 Stefanie Seltmann, Yongqun He SAMEA5248233 Stefanie Seltmann, Yongqun He SAMEA5248235 Stefanie Seltmann, Yongqun He SAMEA5248237 Stefanie Seltmann, Yongqun He SAMEA5248239 Stefanie Seltmann, Yongqun He SAMEA5248240 Stefanie Seltmann, Yongqun He SAMEA5248242 Stefanie Seltmann, Yongqun He SAMEA5248244 Stefanie Seltmann, Yongqun He SAMEA5274196 Stefanie Seltmann, Yongqun He SAMEA5274198 Stefanie Seltmann, Yongqun He SAMEA5274200 Stefanie Seltmann, Yongqun He SAMEA5275617 Stefanie Seltmann, Yongqun He SAMEA5328193 Stefanie Seltmann, Yongqun He SAMEA5340319 Stefanie Seltmann, Yongqun He SAMEA5341577 Stefanie Seltmann, Yongqun He SAMEA5359105 Stefanie Seltmann, Yongqun He SAMEA5398473 Stefanie Seltmann, Yongqun He SAMEA5466090 Stefanie Seltmann, Yongqun He SAMEA5573419 Stefanie Seltmann, Yongqun He SAMEA5573423 Stefanie Seltmann, Yongqun He SAMEA5573667 Stefanie Seltmann, Yongqun He SAMEA5573704 Stefanie Seltmann, Yongqun He SAMEA5573706 Stefanie Seltmann, Yongqun He SAMEA5574029 Stefanie Seltmann, Yongqun He SAMEA5574031 Stefanie Seltmann, Yongqun He SAMEA5574034 Stefanie Seltmann, Yongqun He SAMEA5679957 Stefanie Seltmann, Yongqun He SAMEA5696678 Stefanie Seltmann, Yongqun He SAMEA5696680 Stefanie Seltmann, Yongqun He SAMEA5696682 Stefanie Seltmann, Yongqun He SAMEA5696688 Stefanie Seltmann, Yongqun He SAMEA5712222 Stefanie Seltmann, Yongqun He SAMEA5712224 Stefanie Seltmann, Yongqun He SAMEA5713593 Stefanie Seltmann, Yongqun He SAMEA5727781 Stefanie Seltmann, Yongqun He SAMEA5727782 Stefanie Seltmann, Yongqun He SAMEA5728486 Stefanie Seltmann, Yongqun He SAMEA5728490 Stefanie Seltmann, Yongqun He SAMEA5728495 Stefanie Seltmann, Yongqun He SAMEA5728930 Stefanie Seltmann, Yongqun He SAMEA654195 Stefanie Seltmann, Yongqun He SAMEA723346 Stefanie Seltmann, Yongqun He SAMEA7411168 Stefanie Seltmann, Yongqun He SAMEA7418668 Stefanie Seltmann, Yongqun He SAMEA7420168 Stefanie Seltmann, Yongqun He SAMEA7747168 Stefanie Seltmann, Yongqun He SAMEA7748668 Stefanie Seltmann, Yongqun He SAMEA7751668 Stefanie Seltmann, Yongqun He SAMEA7761418 Stefanie Seltmann, Yongqun He SAMEA7764418 Stefanie Seltmann, Yongqun He SAMEA7767418 Stefanie Seltmann, Yongqun He SAMEA7768918 Stefanie Seltmann, Yongqun He SAMEA7770418 Stefanie Seltmann, Yongqun He SAMEA7771918 Stefanie Seltmann, Yongqun He SAMEA7773418 Stefanie Seltmann, Yongqun He SAMEA7774918 Stefanie Seltmann, Yongqun He SAMEA7776418 Stefanie Seltmann, Yongqun He SAMEA7777918 Stefanie Seltmann, Yongqun He SAMEA7779418 Stefanie Seltmann, Yongqun He SAMEA7780918 Stefanie Seltmann, Yongqun He SAMEA7782418 Stefanie Seltmann, Yongqun He SAMEA7783918 Stefanie Seltmann, Yongqun He SAMEA7791418 Stefanie Seltmann, Yongqun He SAMEA7960918 Stefanie Seltmann, Yongqun He SAMEA994534 Stefanie Seltmann, Yongqun He SAMN02324437 Stefanie Seltmann, Yongqun He SAMN03471450 Stefanie Seltmann, Yongqun He example to be eventually removed example to be eventually removed metadata complete 完整的元数据 Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. metadata complete organizational term PERSON:Alan Ruttenberg organizational term term created to ease viewing/sort terms for development purpose, and will not be included in a release ready for release 准备好发布 Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." ready for release metadata incomplete Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. metadata incomplete uncurated Nothing done yet beyond assigning a unique class ID and proposing a preferred term. uncurated pending final vetting 待最后审批 All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. pending final vetting to be replaced with external ontology term Alan Ruttenberg Terms with this status should eventually replaced with a term from another ontology. group:OBI to be replaced with external ontology term requires discussion A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. Alan Ruttenberg group:OBI requires discussion axiom holds for all times ## Elucidation This is used when the statement/axiom is assumed to hold true 'eternally' ## How to interpret (informal) First the "atemporal" FOL is derived from the OWL using the standard interpretation. This axiom is temporalized by embedding the axiom within a for-all-times quantified sentence. The t argument is added to all instantiation predicates and predicates that use this relation. ## Example Class: nucleus SubClassOf: part_of some cell forall t : forall n : instance_of(n,Nucleus,t) implies exists c : instance_of(c,Cell,t) part_of(n,c,t) ## Notes This interpretation is *not* the same as an at-all-times relation axiom holds for all times 2009-07-31 2017-02-22 Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them. en Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester Alan Ruttenberg Allyson Lister An ontology for the annotation of biomedical and functional genomics experiments. Barry Smith Bill Bug Bjoern Peters Carlo Torniai Chris Mungall Chris Stoeckert Chris Taylor Christian Bolling Cristian Cocos Daniel Rubin Daniel Schober Dawn Field Dirk Derom Elisabetta Manduchi Eric Deutsch Frank Gibson Gilberto Fragoso Helen C. Causton Helen Parkinson Holger Stenzhorn James A. Overton James Malone Jay Greenbaum Jeffrey Grethe Jennifer Fostel Jessica Turner Jie Zheng Joe White John Westbrook Kevin Clancy Larisa Soldatova Lawrence Hunter Liju Fan Luisa Montecchi Matthew Brush Matthew Pocock Melanie Courtot Melissa Haendel Mervi Heiskanen Monnie McGee Norman Morrison OWL-DL Ontology for Biomedical Investigation Philip Lord Philippe Rocca-Serra Pierre Grenon Richard Bruskiewich Richard Scheuermann Robert Stevens Ryan R. Brinkman Stefan Wiemann Susanna-Assunta Sansone Tanya Gray The Ontology for Biomedical Investigations (OBI) is build in a collaborative, international effort and will serve as a resource for annotating biomedical investigations, including the study design, protocols and instrumentation used, the data generated and the types of analysis performed on the data. This ontology arose from the Functional Genomics Investigation Ontology (FuGO) and will contain both terms that are common to all biomedical investigations, including functional genomics investigations and those that are more domain specific. Tina Hernandez-Boussard Trish Whetzel Yongqun He Yvonne Bradford Chris Mungall Terry Meehan Alexander Diehl Melissa Haendel Jim Balhoff Nicole Vasilevsky David Osumi-Sutherland Ceri van Slyke mesoderm mesoderm 中胚层 The middle germ layer of the embryo, between the endoderm and ectoderm. embryonic mesoderm entire mesoderm mesodermal mantle The middle germ layer of the embryo, between the endoderm and ectoderm. embryonic mesoderm entire mesoderm mesodermal mantle 中胚层套膜 整个中胚层 胚胎中胚层 胚胎的中间胚层，在内胚层和外胚层之间。 organ organ 器官 Anatomical structure that performs a specific function or group of functions [WP]. CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4 CARO:0020004 CARO:0020004 EFO:0000634 EFO:0000634 EMAPA:35949 EMAPA:35949 ENVO:01000162 ENVO:01000162 FMA:67498 FMA:67498 MA:0003001 MA:0003001 NCIT:C13018 OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. UBERON:0000062 UBERON:0000062 UMLS:C0178784 UMLS:C0178784 WBbt:0003760 WBbt:0003760 anatomical unit anatomical unit body organ body organ element element uberon uberon Anatomical structure that performs a specific function or group of functions [WP]. CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4 CARO:0020004 EFO:0000634 EMAPA:35949 ENVO:01000162 FMA:67498 MA:0003001 OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. UBERON:0000062 UMLS:C0178784 WBbt:0003760 anatomical unit anatomical unit body organ body organ element element uberon caro v1不包括一般的'器官' 类，仅包括简单的和复合的器官。CARO v2 可以包括器官，参见https://github.com/obophenotype/caro/issues/4 元素 元素 器官通常被观察为明显不同的结构，但也可以作为松散关联的细胞簇存在，所述细胞簇一起工作以执行特定功能或多个特定功能。 执行一种特定功能或功能组的解剖结构[WP]。 解剖单位 解剖单位 身体器官 身体器官 circulatory system circulatory system 循环系统 organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. systema cardiovasculare organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. systema cardiovasculare 传递营养（如氨基酸和电解质）、气体、激素，血细胞等使在体内的细胞中进出，帮助对抗疾病，帮助稳定体温和pH值以保持体内平衡[器官]。 系统性心脏血管 Xiaolin Yang Yuqin Liu Jiangan Xie Hongjie Pan 2.1.162 2019-02-10 Alex Ade Alexander Diehl Allen Xiang Asiyah Yu Lin Stephan Schurer Caty Chung Matthew Brush Uma Vempati An ontology for the domain of cell lines and cell line cells CLO: Cell Line Ontology Citation: Sarntivijai S, Lin Y, Xiang Z, Meehan TF, Diehl AD, Vempati UD, Schürer TC, Pang C, Malone J, Parkinson H, Liu Y, Takatsuki T, Saijo K, Masuya H, Nakamura Y, Brush MH, Haendel MA, Zheng J, Stoeckert CJ, Peters B, Mungall CJ, Carey TE, States DJ, Athey BD, He Y. CLO: The Cell Line Ontology. Journal of Biomedical Semantics. 2014, 5:37. doi:10.1186/2041-1480-5-37. PMID: 25852852. PMCID: PMC4387853. Daniel Cooper Helen Parkinson Hiroshi Masuya James Malone Jie Zheng OWL-DL Sirarat Sarntivijai Stefanie Seltmann The Cell Line Ontology (CLO) is a community-based ontology of cell lines. The CLO is developed to unify publicly available cell line entry data from multiple sources to a standardized logically defined format based on consensus design patterns. Yongqun "Oliver" He (YH) Yue Liu somite Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. epimere epimere mesoderm epithelial somite mesodermal cluster somites somitic mesoderm somitus digestive tract digestive tract 消化道 A tube extending from the mouth to the anus. alimentary canal alimentary tract digestive canal digestive tube enteric tract gut gut tube A tube extending from the mouth to the anus. alimentary canal alimentary tract digestive canal digestive tube enteric tract gut gut tube 从口腔延伸到肛门的管 消化管(digestive tube) 消化道(alimentary canal) 消化道(alimentary tract) 消化道(digestive canal) 肠(gut) 肠管 肠道 central nervous system central nervous system 中枢神经系统 (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG] AAO:0000090 BAMS:CNS BILA:0000080 BTO:0000227 CALOHA:TS-0150 CNS CNS EFO:0000908 EHDAA2:0000225 EHDAA:828 EMAPA:16470 EMAPA:16754 EV:0100163 FBbt:00005094 FMA:55675 GAID:570 MA:0000167 MAT:0000457 MESH:D002490 OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA Part of the nervous system which includes the brain and spinal cord.[AAO] TAO:0000012 The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. UBERON:0001017 UMLS:C0927232 VHOG:0000293 XAO:0000215 ZFA:0000012 cerebrospinal axis cerebrospinal axis neuraxis neuraxis systema nervosum centrale systema nervosum centrale uberon (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG] AAO:0000090 BAMS:CNS BILA:0000080 BTO:0000227 CALOHA:TS-0150 CNS CNS EFO:0000908 EHDAA2:0000225 EHDAA:828 EMAPA:16470 EMAPA:16754 EV:0100163 FBbt:00005094 FMA:55675 GAID:570 MA:0000167 MAT:0000457 MESH:D002490 OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA Part of the nervous system which includes the brain and spinal cord.[AAO] TAO:0000012 The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. UBERON:0001017 UMLS:C0927232 VHOG:0000293 XAO:0000215 ZFA:0000012 cerebrospinal axis cerebrospinal axis neuraxis neuraxis systema nervosum centrale systema nervosum centrale uberon (...)在其发展的某个阶段，每种脊索动物都表现出该组的五个独特的衍生特征或突触：(...)(4)位于脊索(...)背侧的单个管状神经索(参考1)； 神经管注定分化为脑和脊髓(中枢神经系统)(参考文献2)； 总之，我们的数据证明了一个非常有力的例子，即正在发育中的中枢神经系统（中枢神经系统）的复杂分子内外侧结构，在沙蚕和脊椎动物中，已经存在于它们的最后一个共同祖先Urbilateria。双翼神经系统集中的概念意味着神经元类型集中在躯干的一侧，如在脊椎动物和许多无脊椎动物，包括沙蚕，在那里它们分离并且变得空间上有组织（与扩散的神经网相反）。我们的数据显示环节动物和脊椎动物CNS的大部分空间组织已经存在于它们的最后一个共同祖先中，这意味着熊胆已经拥有CNS(参考文献3)。[well established][VHOG] 中枢神经系统(CNS)是神经系统的一部分，其包括视网膜的脑、脊髓和神经细胞层 (CUMBO)。 中枢神经系统是起着整合和协调功能的核心神经系统。在脊椎动物中，它由神经管衍生物组成：脑和脊髓。在无脊椎动物中，它包括中央神经节和神经索。 大脑和脊髓。Kimmel et al, 1995.[TAO] 神经系统的一部分，包括大脑和脊髓。[AAO] 神经轴 神经轴 系统神经中枢 系统神经中枢 脑脊髓轴 脑脊髓轴 musculature of body musculature of body 身体肌肉系统 The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. muscle system muscle system of body muscular system musculature system muskelsystem set of all muscles set of muscles of body vertebrate muscular system The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. muscle system muscle system of body muscular system musculature system muskelsystem set of all muscles set of muscles of body vertebrate muscular system 一整套肌肉 肌肉系统(muscle system) 肌肉系统(muscular system) 肌肉系统(musculature system) 肌肉系统(muskelsystem) 肌肉骨骼系统的细分，包括身体的所有肌肉[VSAO，修改]。 脊椎动物肌肉系统 身体肌肉系统 身体肌肉组 has role has role A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence has role has_role this person has role this investigator role (more colloquially: this person has this role of investigator) never in taxon