Exposure ontology (ExO)
type: Ontology
version IRI: exo.owl
description: ExO is intended to bridge the gap between exposure science and diverse environmental health disciplines including toxicology, epidemiology, disease surveillance, and epigenetics.
license: https://creativecommons.org/licenses/by/4.0/
default-namespace: source
has_obo_format_version: 1.2
version info: 2025-08-29

definition
type: AnnotationProperty

created by
type: AnnotationProperty

creation date
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

id
type: AnnotationProperty

shorthand
type: AnnotationProperty

BFO_0000050
type: ObjectProperty
definition: For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)
database_cross_reference: BFO:0000050
has_obo_namespace: source
id: part_of
shorthand: part_of

Axiom
annotated source: BFO_0000050
annotated property: definition
annotated target: For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)
database_cross_reference: PMID:15892874

has_part
type: ObjectProperty
type: TransitiveProperty
database_cross_reference: BFO:0000051
has_obo_namespace: source
id: has_part
shorthand: has_part

interacts with
type: ObjectProperty
database_cross_reference: RO:0002434
has_obo_namespace: source
id: interacts_with
shorthand: interacts_with

characterizes
type: ObjectProperty
has_obo_namespace: source
id: characterizes

interacts_with_an_exposure_receptor_via
type: ObjectProperty
has_obo_namespace: source
id: interacts_with_an_exposure_receptor_via

interacts_with_an_exposure stressor_via
type: ObjectProperty
has_obo_namespace: source
id: interacts_with_an_exposure_stressor_via

is_associated_with
type: ObjectProperty
has_obo_namespace: source
id: is_associated_with

process
type: Class
has_obo_namespace: source
id: BFO:0000015

intravenous injection route
type: Class
subclass of: injection route
definition: An injection exposure route which takes place within or is administered into a vein
date: 2022-12-15T16:27:20Z
created by: http://orcid.org/0000-0002-7463-6306
has_obo_namespace: source
id: EXO:0000160

Axiom
annotated source: intravenous injection route
annotated property: definition
annotated target: An injection exposure route which takes place within or is administered into a vein
database_cross_reference: https://www.merriam-webster.com/dictionary/intravenous

subcutaneous injection route
type: Class
subclass of: injection route
definition: An injection route of exposure which is administered under the skin.
date: 2022-12-15T16:28:10Z
created by: http://orcid.org/0000-0002-7463-6306
has_obo_namespace: source
id: EXO:0000161

Axiom
annotated source: subcutaneous injection route
annotated property: definition
annotated target: An injection route of exposure which is administered under the skin.
database_cross_reference: https://www.merriam-webster.com/dictionary/subcutaneous

intramuscular injection route
type: Class
subclass of: injection route
definition: An injection route of exposure which is administered into a muscle.
date: 2022-12-15T16:28:46Z
created by: http://orcid.org/0000-0002-7463-6306
has_obo_namespace: source
id: EXO:0000162

Axiom
annotated source: intramuscular injection route
annotated property: definition
annotated target: An injection route of exposure which is administered into a muscle.
database_cross_reference: https://www.merriam-webster.com/dictionary/intramuscular

exposure stressor
type: Class
subclass of: Restriction
  on property: interacts with
  some values from: exposure recipient
subclass of: Restriction
  on property: interacts_with_an_exposure_receptor_via
  some values from: exposure event
definition: An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure_receptor during an exposure event.
creation date: 2010-09-21T02:43:50Z
has_obo_namespace: exposure_stressor
id: ExO:0000000

Axiom
annotated source: exposure stressor
annotated property: definition
annotated target: An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure_receptor during an exposure event.
database_cross_reference: CTD:curators

exposure recipient
type: Class
subclass of: Restriction
  on property: interacts with
  some values from: exposure stressor
definition: An entity (e.g., a human, human population, or a human organ) that interacts with an exposure stimulus during an exposure event.
created by: cmattin
creation date: 2010-09-21T02:45:36Z
has_exact_synonym: exposure receptor
has_exact_synonym: exposure target
has_obo_namespace: exposure_recipient
id: ExO:0000001

Axiom
annotated source: exposure recipient
annotated property: definition
annotated target: An entity (e.g., a human, human population, or a human organ) that interacts with an exposure stimulus during an exposure event.
database_cross_reference: CTD:curators

exposure event
type: Class
subclass of: process
subclass of: Restriction
  on property: has_part
  some values from: exposure stressor
subclass of: Restriction
  on property: has_part
  some values from: exposure recipient
subclass of: Restriction
  on property: interacts_with_an_exposure_receptor_via
  some values from: exposure stressor
subclass of: Restriction
  on property: interacts_with_an_exposure stressor_via
  some values from: exposure recipient
definition: An interaction between an exposure stressor and an exposure_receptor.
created by: cmattin
creation date: 2010-09-21T02:47:00Z
has_obo_namespace: exposure_event
id: ExO:0000002

Axiom
annotated source: exposure event
annotated property: definition
annotated target: An interaction between an exposure stressor and an exposure_receptor.
database_cross_reference: CTD:curators

exposure outcome
type: Class
subclass of: Restriction
  on property: is_associated_with
  some values from: exposure event
definition: Entity that results from the interaction between and exposure_receptor and an exposure stressor during an exposure event.
created by: cmattin
creation date: 2010-09-21T02:48:49Z
has_obo_namespace: exposure_outcome
has_related_synonym: interaction outcome
id: ExO:0000003

Axiom
annotated source: exposure outcome
annotated property: definition
annotated target: Entity that results from the interaction between and exposure_receptor and an exposure stressor during an exposure event.
database_cross_reference: CTD:curators

exposure transport path
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure stressor
definition: A exposure transport path is the course an agent takes from the source to the target.
created by: cmattin
creation date: 2011-01-10T04:29:33Z
has_obo_namespace: exposure_stressor
id: ExO:0000004

Axiom
annotated source: exposure transport path
annotated property: definition
annotated target: A exposure transport path is the course an agent takes from the source to the target.
database_cross_reference: CTD:curators

biological agent
type: Class
subclass of: exposure stressor
definition: An agent of biological origin.
created by: cmattin
creation date: 2010-09-21T10:09:17Z
has_obo_namespace: exposure_stressor
id: ExO:0000005

Axiom
annotated source: biological agent
annotated property: definition
annotated target: An agent of biological origin.
database_cross_reference: CTD:curators

chemical agent
type: Class
subclass of: exposure stressor
definition: An agent of chemical origin.
created by: cmattin
creation date: 2010-09-21T10:12:29Z
has_obo_namespace: exposure_stressor
id: ExO:0000006

ecological perturbation
type: Class
subclass of: exposure stressor
definition: An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment.
created by: cmattin
creation date: 2010-09-21T10:14:38Z
has_obo_namespace: exposure_stressor
id: ExO:0000007

physical agent
type: Class
subclass of: exposure stressor
definition: An agent as a source of energy that may cause injury or disease (e.g., noise, vibration, radiation, temperature extremes).
created by: cmattin
creation date: 2010-09-21T10:15:42Z
has_obo_namespace: exposure_stressor
id: ExO:0000008

psychosocial agent
type: Class
subclass of: exposure stressor
definition: An agent that interferes with one's psychological development in and interaction with a social environment.
created by: cmattin
creation date: 2010-09-21T10:16:35Z
has_obo_namespace: exposure_stressor
id: ExO:0000009

air transport path
type: Class
subclass of: exposure transport path
definition: A transport path that allows a stressor to interact with a receptor via air.
created by: cmattin
creation date: 2011-01-10T04:29:46Z
has_obo_namespace: exposure_transport_path
id: ExO:0000010

Axiom
annotated source: air transport path
annotated property: definition
annotated target: A transport path that allows a stressor to interact with a receptor via air.
database_cross_reference: CTD:curators

biomechanical agent
type: Class
subclass of: exposure stressor
definition: A mechanical agent applied to biological systems, such as humans, animals, plants, organs, and cells
created by: cmattin
creation date: 2011-01-10T04:17:29Z
has_obo_namespace: exposure_stressor
id: ExO:0000011

Axiom
annotated source: biomechanical agent
annotated property: definition
annotated target: A mechanical agent applied to biological systems, such as humans, animals, plants, organs, and cells
database_cross_reference: CTD:curators

habitat degradation
type: Class
subclass of: ecological perturbation
definition: An ecological perturbation that results from the deterioration of an ecological or environmental area that is inhabited by a particular species of animal, plant or other type of organism.
created by: cmattin
creation date: 2011-01-10T04:18:53Z
has_obo_namespace: exposure_stressor
id: ExO:0000012

Axiom
annotated source: habitat degradation
annotated property: definition
annotated target: An ecological perturbation that results from the deterioration of an ecological or environmental area that is inhabited by a particular species of animal, plant or other type of organism.
database_cross_reference: GOC:hjd

acid rain
type: Class
subclass of: ecological perturbation
definition: An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water.
created by: cmattin
creation date: 2011-01-10T04:19:11Z
has_obo_namespace: exposure_stressor
id: ExO:0000013

Axiom
annotated source: acid rain
annotated property: definition
annotated target: An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water.
database_cross_reference: MESH:D015258
database_cross_reference: UMLS:C0001111

climate change
type: Class
subclass of: ecological perturbation
definition: An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.
created by: cmattin
creation date: 2011-01-10T04:19:26Z
has_obo_namespace: exposure_stressor
id: ExO:0000014

Axiom
annotated source: climate change
annotated property: definition
annotated target: An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.
database_cross_reference: MESH:D057231
database_cross_reference: UMLS:C2718051

poverty
type: Class
subclass of: psychosocial agent
definition: A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level.
created by: cmattin
creation date: 2011-01-10T04:19:54Z
has_obo_namespace: exposure_stressor
has_related_synonym: indigency
id: ExO:0000015

Axiom
annotated source: poverty
annotated property: definition
annotated target: A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level.
database_cross_reference: MESH:D011203

source
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure stressor
definition: Where something is available or from where it originates.
created by: cmattin
creation date: 2011-01-10T04:20:11Z
database_cross_reference: CTD:curators
has_obo_namespace: exposure_stressor
id: ExO:0000016

Axiom
annotated source: source
annotated property: definition
annotated target: Where something is available or from where it originates.
database_cross_reference: UMLS:C0449416

location
type: Class
subclass of: exposure event
subclass of: spatial quality
definition: A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity.
created by: cmattin
creation date: 2011-01-10T04:22:40Z
has_obo_namespace: spatial_quality
has_related_synonym: Placement
id: ExO:0000017

Axiom
annotated source: location
annotated property: definition
annotated target: A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity.
database_cross_reference: PATO:0000140

exogenous
type: Class
subclass of: location
definition: Substances or processes that originate outside of an organism or a system.
created by: cmattin
creation date: 2011-01-10T04:23:00Z
has_obo_namespace: spatial_quality
id: ExO:0000018

Axiom
annotated source: exogenous
annotated property: definition
annotated target: Substances or processes that originate outside of an organism or a system.
database_cross_reference: CTD:curators

indoor
type: Class
subclass of: location
definition: A location that is happening or arising or located inside some limits, or especially, some surface.
created by: cmattin
creation date: 2011-01-10T04:23:14Z
has_obo_namespace: spatial_quality
id: ExO:0000019

Axiom
annotated source: indoor
annotated property: definition
annotated target: A location that is happening or arising or located inside some limits, or especially, some surface.
database_cross_reference: CTD:curators

outdoor
type: Class
subclass of: location
definition: An exogenous location that is happening or arising or located outside
created by: cmattin
creation date: 2011-01-10T04:23:24Z
has_obo_namespace: spatial_quality
id: ExO:0000020

Axiom
annotated source: outdoor
annotated property: definition
annotated target: An exogenous location that is happening or arising or located outside
database_cross_reference: CTD:curators

endogenous
type: Class
subclass of: location
definition: Substances or processes that originate within an organism or a system.
created by: cmattin
creation date: 2011-01-10T04:23:36Z
has_obo_namespace: spatial_quality
id: ExO:0000021

Axiom
annotated source: endogenous
annotated property: definition
annotated target: Substances or processes that originate within an organism or a system.
database_cross_reference: CTD:curators

exposure stimulus
type: Class
definition: Any agent, entity, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.
created by: http://orcid.org/0000-0002-7463-6306
creation date: 2021-10-20T17:44:37Z
has_obo_namespace: source
id: ExO:0000022

process
type: Class
subclass of: source
definition: The act of taking something through an established and usually routine set of procedures to convert it from one form to another.
created by: cmattin
creation date: 2011-01-10T04:24:15Z
has_obo_namespace: source
id: ExO:0000023

Axiom
annotated source: process
annotated property: definition
annotated target: The act of taking something through an established and usually routine set of procedures to convert it from one form to another.
database_cross_reference: CTD:curators

biological process
type: Class
subclass of: process
definition: A process occurring in living organisms.
created by: cmattin
creation date: 2011-01-10T04:24:45Z
has_obo_namespace: source
id: ExO:0000024

Axiom
annotated source: biological process
annotated property: definition
annotated target: A process occurring in living organisms.
database_cross_reference: CTD:curators

industrial process
type: Class
subclass of: process
definition: A systematic series of mechanical or chemical operations that produce or manufacture something.
created by: cmattin
creation date: 2011-01-10T04:24:59Z
has_obo_namespace: source
id: ExO:0000025

Axiom
annotated source: industrial process
annotated property: definition
annotated target: A systematic series of mechanical or chemical operations that produce or manufacture something.
database_cross_reference: CTD:curators

agricultural process
type: Class
subclass of: process
definition: The exposure process of producing food, feed, fiber and other desired products by cultivation of certain plants or raising domesticated animals (livestock).
created by: cmattin
creation date: 2011-01-10T04:25:09Z
has_obo_namespace: source
id: ExO:0000026

Axiom
annotated source: agricultural process
annotated property: definition
annotated target: The exposure process of producing food, feed, fiber and other desired products by cultivation of certain plants or raising domesticated animals (livestock).
database_cross_reference: CTD:curators

water transport path
type: Class
subclass of: exposure transport path
definition: An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via water.
created by: cmattin
creation date: 2011-01-10T04:29:57Z
has_obo_namespace: exposure_transport_path
id: ExO:0000028

Axiom
annotated source: water transport path
annotated property: definition
annotated target: An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via water.
database_cross_reference: CTD:curators

soil transport path
type: Class
subclass of: exposure transport path
definition: An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via soil.
created by: cmattin
creation date: 2011-01-10T04:30:08Z
has_obo_namespace: exposure_transport_path
id: ExO:0000029

Axiom
annotated source: soil transport path
annotated property: definition
annotated target: An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via soil.
database_cross_reference: CTD:curators

ecosphere
type: Class
subclass of: exposure recipient
definition: The earth, all of the organisms living on it, and all of the environmental factors, which act on the organisms. The volume of area where biological matter can exist, slightly above, on or below ground level.
created by: cmattin
creation date: 2011-01-10T09:26:27Z
has_obo_namespace: exposure_receptor
id: ExO:0000030

Axiom
annotated source: ecosphere
annotated property: definition
annotated target: The earth, all of the organisms living on it, and all of the environmental factors, which act on the organisms. The volume of area where biological matter can exist, slightly above, on or below ground level.
database_cross_reference: XCTD:curators

biosphere
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: ecosphere
definition: MERGED DEFINITION:\nTARGET DEFINITION: An exposure_receptor that is the global ecological system integrating all living beings and their relationships, including their interaction with the elements of the lithosphere, hydrosphere and atmosphere.\n--------------------\nSOURCE DEFINITION: An exposure_receptor that is the part of the environment that is made or modified by humans for use in human activities and human habitats.
created by: cmattin
creation date: 2011-01-10T09:27:26Z
has_alternative_id: ExO:0000032
has_exact_synonym: anthrosphere
has_obo_namespace: exposure_receptor
id: ExO:0000031

Axiom
annotated source: biosphere
annotated property: definition
annotated target: MERGED DEFINITION:\nTARGET DEFINITION: An exposure_receptor that is the global ecological system integrating all living beings and their relationships, including their interaction with the elements of the lithosphere, hydrosphere and atmosphere.\n--------------------\nSOURCE DEFINITION: An exposure_receptor that is the part of the environment that is made or modified by humans for use in human activities and human habitats.
database_cross_reference: GOC:hjd

ExO_0000032
type: Class
IAO_0000231: IAO_0000227
IAO_0100001: biosphere
deprecated: true

human population
type: Class
subclass of: exposure recipient
subclass of: Restriction
  on property: BFO_0000050
  some values from: biosphere
definition: An exposure_receptor that is a group of Homo sapiens inhabiting a given area.
created by: cmattin
creation date: 2011-01-10T09:28:02Z
has_obo_namespace: exposure_receptor
id: ExO:0000033

Axiom
annotated source: human population
annotated property: definition
annotated target: An exposure_receptor that is a group of Homo sapiens inhabiting a given area.
database_cross_reference: CTD:curators

occupation
type: Class
subclass of: human attribute
definition: An individual attribute that is the usual or principal work or business of an individual.
created by: cmattin
creation date: 2011-01-10T09:28:22Z
has_obo_namespace: human_attribute
id: ExO:0000034

Axiom
annotated source: occupation
annotated property: definition
annotated target: An individual attribute that is the usual or principal work or business of an individual.
database_cross_reference: CTD:curators

genetic background
type: Class
subclass of: human attribute
definition: The individual attribute that is the genes and their composition that are characteristic of an individual or population.
created by: cmattin
creation date: 2011-01-10T09:28:41Z
has_obo_namespace: human_attribute
id: ExO:0000035

Axiom
annotated source: genetic background
annotated property: definition
annotated target: The individual attribute that is the genes and their composition that are characteristic of an individual or population.
database_cross_reference: CTD:curators

lifestage
type: Class
subclass of: human attribute
definition: A individual attribute that is a particular period in the life of an organism.
created by: cmattin
creation date: 2011-01-10T09:29:39Z
has_obo_namespace: human_attribute
id: ExO:0000037

Axiom
annotated source: lifestage
annotated property: definition
annotated target: A individual attribute that is a particular period in the life of an organism.
database_cross_reference: CTD:curators

health status
type: Class
subclass of: human attribute
definition: The condition of an organism in all aspects (e.g., functional or metabolic efficiency).
created by: cmattin
creation date: 2011-01-10T09:29:51Z
has_obo_namespace: human_attribute
id: ExO:0000038

Axiom
annotated source: health status
annotated property: definition
annotated target: The condition of an organism in all aspects (e.g., functional or metabolic efficiency).
database_cross_reference: CTD:curators

social characteristic
type: Class
subclass of: human attribute
definition: An individual attribute human society and its modes of organization.
created by: cmattin
creation date: 2011-01-10T09:30:08Z
has_obo_namespace: human_attribute
id: ExO:0000039

Axiom
annotated source: social characteristic
annotated property: definition
annotated target: An individual attribute human society and its modes of organization.
database_cross_reference: CTD:curators

cultural background
type: Class
subclass of: social characteristic
definition: A social characteristic about or relating to the arts and manners favored or practiced by a group.
created by: cmattin
creation date: 2011-01-10T09:30:27Z
has_obo_namespace: human_attribute
id: ExO:0000040

Axiom
annotated source: cultural background
annotated property: definition
annotated target: A social characteristic about or relating to the arts and manners favored or practiced by a group.
database_cross_reference: CTD:curators

education
type: Class
subclass of: social characteristic
definition: The act or process of imparting or acquiring knowledge.
created by: cmattin
creation date: 2011-01-10T09:30:40Z
has_obo_namespace: human_attribute
id: ExO:0000041

Axiom
annotated source: education
annotated property: definition
annotated target: The act or process of imparting or acquiring knowledge.
database_cross_reference: CTD:curators

human individual
type: Class
subclass of: exposure recipient
subclass of: Restriction
  on property: BFO_0000050
  some values from: human population
definition: Being or characteristic of a single thing or person.
created by: cmattin
creation date: 2011-01-10T09:30:56Z
has_obo_namespace: exposure_receptor
id: ExO:0000042

Axiom
annotated source: human individual
annotated property: definition
annotated target: Being or characteristic of a single thing or person.
database_cross_reference: CTD:curators

anatomy
type: Class
subclass of: human attribute
subclass of: phenotype
definition: The individual attribute describing the structure of a living organism.
created by: cmattin
creation date: 2011-01-10T09:31:27Z
has_obo_namespace: human_attribute
id: ExO:0000043

Axiom
annotated source: anatomy
annotated property: definition
annotated target: The individual attribute describing the structure of a living organism.
database_cross_reference: CTD:curators

organ
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
definition: Anatomical structure, which consists of the maximal set of organ parts so connected to one another that together they constitute a unit of macroscopic anatomy, structurally distinct from other such units. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary.
created by: cmattin
creation date: 2011-01-10T09:31:44Z
has_obo_namespace: anatomy
id: ExO:0000044

Axiom
annotated source: organ
annotated property: definition
annotated target: Anatomical structure, which consists of the maximal set of organ parts so connected to one another that together they constitute a unit of macroscopic anatomy, structurally distinct from other such units. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary.
database_cross_reference: FMA:67498

tissue
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
definition: Anatomical structure, which consists of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships. Examples: epithelium, muscle tissue, connective tissue, neural tissue, lymphoid tissue.
created by: cmattin
creation date: 2011-01-10T09:31:55Z
has_obo_namespace: anatomy
id: ExO:0000045

Axiom
annotated source: tissue
annotated property: definition
annotated target: Anatomical structure, which consists of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships. Examples: epithelium, muscle tissue, connective tissue, neural tissue, lymphoid tissue.
database_cross_reference: FMA:9637

cell
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
definition: Anatomical structure that consists of a cell compartment surrounded by a plasma membrane; together with other cells and intercellular matrix, it constitutes tissues. Examples: lymphocyte, fibroblast, erythrocyte, neuron.
created by: cmattin
creation date: 2011-01-10T09:32:07Z
has_obo_namespace: anatomy
id: ExO:0000046

Axiom
annotated source: cell
annotated property: definition
annotated target: Anatomical structure that consists of a cell compartment surrounded by a plasma membrane; together with other cells and intercellular matrix, it constitutes tissues. Examples: lymphocyte, fibroblast, erythrocyte, neuron.
database_cross_reference: FMA:68646

biological molecules
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
definition: Substances made up of atoms, such as proteins, nucleic acids, lipids and carbohydrates that are produced only by living organisms. Biological molecules are often referred to as macromolecules or biopolymers.
created by: cmattin
creation date: 2011-01-10T09:32:26Z
has_obo_namespace: anatomy
id: ExO:0000047

Axiom
annotated source: biological molecules
annotated property: definition
annotated target: Substances made up of atoms, such as proteins, nucleic acids, lipids and carbohydrates that are produced only by living organisms. Biological molecules are often referred to as macromolecules or biopolymers.
database_cross_reference: CTD:curators

built environment
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: biosphere
definition: Human-made surroundings that provide the setting for human activity, ranging in scale from personal shelter and buildings to neighborhoods and cite, and can often include their supporting infrastructure, such as water supply or energy networks.
created by: cmattin
creation date: 2011-01-10T09:32:56Z
has_obo_namespace: exposure_receptor
id: ExO:0000048

Axiom
annotated source: built environment
annotated property: definition
annotated target: Human-made surroundings that provide the setting for human activity, ranging in scale from personal shelter and buildings to neighborhoods and cite, and can often include their supporting infrastructure, such as water supply or energy networks.
database_cross_reference: CTD:curators

temporal quality
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure event
subclass of: Restriction
  on property: BFO_0000050
  some values from: source
subclass of: Restriction
  on property: BFO_0000050
  some values from: assay
definition: A quality of a single process inhering in a bearer by virtue of the bearer's occurrence.
created by: cmattin
creation date: 2011-01-10T09:37:16Z
has_obo_namespace: temporal_quality
has_related_synonym: Incidence
has_related_synonym: occurrence quality
id: ExO:0000050

Axiom
annotated source: temporal quality
annotated property: definition
annotated target: A quality of a single process inhering in a bearer by virtue of the bearer's occurrence.
database_cross_reference: PATO:0000057

frequency
type: Class
subclass of: temporal quality
definition: A physical quality, which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time.
created by: cmattin
creation date: 2011-01-10T09:37:46Z
has_obo_namespace: temporal_quality
id: ExO:0000051

Axiom
annotated source: frequency
annotated property: definition
annotated target: A physical quality, which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time.
database_cross_reference: PATO:0000044

intermittent
type: Class
subclass of: frequency
definition: A quality of a single process inhering in a bearer by virtue of the bearer's being marked by breaks or interruptions.
created by: cmattin
creation date: 2011-01-10T09:37:57Z
has_obo_namespace: temporal_quality
has_related_synonym: discontinuous
has_related_synonym: interrupted
id: ExO:0000052

Axiom
annotated source: intermittent
annotated property: definition
annotated target: A quality of a single process inhering in a bearer by virtue of the bearer's being marked by breaks or interruptions.
database_cross_reference: PATO:0000690

continuous
type: Class
subclass of: frequency
definition: A quality of a single process inhering in a bearer by virtue of the bearer's being uninterrupted in time, sequence, substance, or extent.
created by: cmattin
creation date: 2011-01-10T09:38:09Z
has_obo_namespace: temporal_quality
has_related_synonym: uninterrupted
id: ExO:0000053

Axiom
annotated source: continuous
annotated property: definition
annotated target: A quality of a single process inhering in a bearer by virtue of the bearer's being uninterrupted in time, sequence, substance, or extent.
database_cross_reference: PATO:0000689

duration
type: Class
subclass of: temporal quality
definition: Amount of time during which an event persists.
created by: cmattin
creation date: 2011-01-10T09:38:24Z
has_obo_namespace: temporal_quality
id: ExO:0000054

Axiom
annotated source: duration
annotated property: definition
annotated target: Amount of time during which an event persists.
database_cross_reference: SBO:0000347

exposure route
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure event
definition: The way people, sample, or other living organisms come into contact with a stressor.
created by: cmattin
creation date: 2011-01-10T09:38:37Z
has_obo_namespace: exposure_event
id: ExO:0000055

Axiom
annotated source: exposure route
annotated property: definition
annotated target: The way people, sample, or other living organisms come into contact with a stressor.
database_cross_reference: CTD:curators

ingestion route
type: Class
subclass of: gastrointestinal tract route
definition: An exposure route in which a subject or sample comes in contact with a stressor by swallowing the stressor or a substance containing the stressor.
created by: cmattin
creation date: 2011-01-10T09:38:47Z
has_obo_namespace: route
id: ExO:0000056

Axiom
annotated source: ingestion route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor by swallowing the stressor or a substance containing the stressor.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

inhalation route
type: Class
subclass of: exposure route
definition: An exposure route in which a subject or sample comes in contact with a stressor through breathing.
created by: cmattin
creation date: 2011-01-10T09:38:59Z
has_obo_namespace: route
id: ExO:0000057

Axiom
annotated source: inhalation route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor through breathing.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

absorption
type: Class
subclass of: exposure route
definition: The process of one material (absorbent) being retained by another (absorbate).
created by: cmattin
creation date: 2011-01-10T09:39:11Z
has_obo_namespace: route
id: ExO:0000058

Axiom
annotated source: absorption
annotated property: definition
annotated target: The process of one material (absorbent) being retained by another (absorbate).
database_cross_reference: REX:0000188

leaching
type: Class
subclass of: exposure route
definition: The extraction of certain materials from a carrier into a liquid (usually, but not always a solvent).
created by: cmattin
creation date: 2011-01-10T09:39:25Z
has_obo_namespace: route
id: ExO:0000059

Axiom
annotated source: leaching
annotated property: definition
annotated target: The extraction of certain materials from a carrier into a liquid (usually, but not always a solvent).
database_cross_reference: GOC:hjd

injection route
type: Class
subclass of: exposure route
definition: An exposure route in which a subject or sample comes in contact with a stressor that has directly entered the body through punctures, bites, or needles.
created by: cmattin
creation date: 2011-01-10T09:39:37Z
has_obo_namespace: route
id: ExO:0000060

Axiom
annotated source: injection route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor that has directly entered the body through punctures, bites, or needles.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

subcutaneous tissue
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
subclass of: Restriction
  on property: targeted to
  some values from: injection route
definition: Superficial fascia.
created by: cmattin
creation date: 2011-01-10T09:39:49Z
has_obo_namespace: anatomy
has_related_synonym: Superficial fascia
id: ExO:0000061

Axiom
annotated source: subcutaneous tissue
annotated property: definition
annotated target: Superficial fascia.
database_cross_reference: FMA:9630

muscle
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
subclass of: Restriction
  on property: targeted to
  some values from: injection route
definition: The contractile tissue of animals and is derived from the mesodermal layer of embryonic germ cells.
created by: cmattin
creation date: 2011-01-10T09:40:05Z
has_obo_namespace: anatomy
id: ExO:0000062

Axiom
annotated source: muscle
annotated property: definition
annotated target: The contractile tissue of animals and is derived from the mesodermal layer of embryonic germ cells.
database_cross_reference: FMA:30316

blood
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: anatomy
subclass of: Restriction
  on property: targeted to
  some values from: injection route
definition: Body substance which consists of plasma and blood cells.
created by: cmattin
creation date: 2011-01-10T09:40:25Z
has_obo_namespace: anatomy
id: ExO:0000063

Axiom
annotated source: blood
annotated property: definition
annotated target: Body substance which consists of plasma and blood cells.
database_cross_reference: FMA:9670

assay
type: Class
subclass of: Restriction
  on property: characterizes
  some values from: exposure event
definition: A planned process with the objective to produce information about some evaluant.
created by: cmattin
creation date: 2011-01-11T01:22:29Z
has_obo_namespace: assay
id: ExO:0000064

Axiom
annotated source: assay
annotated property: definition
annotated target: A planned process with the objective to produce information about some evaluant.
database_cross_reference: OBI:0000070

intensity
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure event
subclass of: Restriction
  on property: BFO_0000050
  some values from: source
subclass of: Restriction
  on property: BFO_0000050
  some values from: assay
definition: A quality inhering in a bearer by virtue of the bearer possessing or displaying a distinctive feature in type or degree or effect or force.
created by: cmattin
creation date: 2011-01-11T01:23:06Z
has_obo_namespace: exposure_event
id: ExO:0000065

Axiom
annotated source: intensity
annotated property: definition
annotated target: A quality inhering in a bearer by virtue of the bearer possessing or displaying a distinctive feature in type or degree or effect or force.
database_cross_reference: PATO:0000049

unit
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: temporal quality
subclass of: Restriction
  on property: BFO_0000050
  some values from: measurement
subclass of: Restriction
  on property: has_part
  some values from: intensity
definition: A unit of measurement is a standardized quantity of a physical quality.
created by: cmattin
creation date: 2011-01-11T01:23:54Z
has_obo_namespace: unit
id: ExO:0000066

Axiom
annotated source: unit
annotated property: definition
annotated target: A unit of measurement is a standardized quantity of a physical quality.
database_cross_reference: UO:0000000

measurement
type: Class
subclass of: assay
definition: A measurement is an information entity that is a recording of the output of a measurement such as produced by an instrument.
created by: cmattin
creation date: 2011-01-11T01:24:53Z
has_obo_namespace: assay
id: ExO:0000067

Axiom
annotated source: measurement
annotated property: definition
annotated target: A measurement is an information entity that is a recording of the output of a measurement such as produced by an instrument.
database_cross_reference: EFO:0001444

time
type: Class
subclass of: temporal quality
definition: An exposure quality in which events occur in sequence.
created by: cmattin
creation date: 2011-01-11T01:26:02Z
has_obo_namespace: temporal_quality
id: ExO:0000070

Axiom
annotated source: time
annotated property: definition
annotated target: An exposure quality in which events occur in sequence.
database_cross_reference: PATO:0000165

biological marker
type: Class
subclass of: assay
definition: A substance used as an indicator of a biological state.
created by: cmattin
creation date: 2011-01-11T01:26:20Z
has_obo_namespace: assay
id: ExO:0000071

Axiom
annotated source: biological marker
annotated property: definition
annotated target: A substance used as an indicator of a biological state.
database_cross_reference: CHEBI:59163

model
type: Class
subclass of: assay
definition: A representation.
created by: cmattin
creation date: 2011-01-11T01:26:51Z
has_obo_namespace: assay
id: ExO:0000072

Axiom
annotated source: model
annotated property: definition
annotated target: A representation.
database_cross_reference: CTD:curators

conceptual
type: Class
subclass of: model
definition: A representation of a particular system or subject matter that may only be drawn on paper, described in words, or imagined in the mind.
created by: cmattin
creation date: 2011-01-11T01:27:05Z
has_obo_namespace: assay
id: ExO:0000073

Axiom
annotated source: conceptual
annotated property: definition
annotated target: A representation of a particular system or subject matter that may only be drawn on paper, described in words, or imagined in the mind.
database_cross_reference: CTD:curators

mathematical
type: Class
subclass of: model
definition: A representation of a particular system or subject matter that can be computed.
created by: cmattin
creation date: 2011-01-11T01:27:35Z
has_obo_namespace: assay
id: ExO:0000074

Axiom
annotated source: mathematical
annotated property: definition
annotated target: A representation of a particular system or subject matter that can be computed.
database_cross_reference: CTD:curators

computational
type: Class
subclass of: model
definition: A representation of a particular system or subject matter that is computer-derived.
created by: cmattin
creation date: 2011-01-11T01:27:47Z
has_obo_namespace: assay
id: ExO:0000075

Axiom
annotated source: computational
annotated property: definition
annotated target: A representation of a particular system or subject matter that is computer-derived.
database_cross_reference: CTD:curators

dose
type: Class
subclass of: exposure outcome
subclass of: intensity
definition: The total quantity or strength of a substance administered at one time.
created by: cmattin
creation date: 2011-01-11T01:28:26Z
has_obo_namespace: exposure_event
id: ExO:0000076

Axiom
annotated source: dose
annotated property: definition
annotated target: The total quantity or strength of a substance administered at one time.
database_cross_reference: EFO:0000428

biological response
type: Class
subclass of: exposure outcome
created by: cmattin
creation date: 2011-01-11T01:29:49Z
has_obo_namespace: exposure_outcome
id: ExO:0000077

molecular response
type: Class
subclass of: biological response
created by: cmattin
creation date: 2011-01-11T01:30:06Z
has_obo_namespace: exposure_outcome
id: ExO:0000078

disease
type: Class
subclass of: biological response
subclass of: influencing factor
definition: A disease is a pattern of abnormal functioning, or abnormal localization of normal functioning, and/or abnormal localization of constituents when compared to other members of that species.
created by: cmattin
creation date: 2011-01-11T01:30:35Z
has_obo_namespace: exposure_outcome
id: ExO:0000079

Axiom
annotated source: disease
annotated property: definition
annotated target: A disease is a pattern of abnormal functioning, or abnormal localization of normal functioning, and/or abnormal localization of constituents when compared to other members of that species.
database_cross_reference: DOExO:4
database_cross_reference: MESH:D004194
database_cross_reference: UMLS:C0012634

symptom
type: Class
subclass of: biological response
definition: A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
created by: cmattin
creation date: 2011-01-11T01:30:47Z
has_obo_namespace: exposure_outcome
id: ExO:0000080

Axiom
annotated source: symptom
annotated property: definition
annotated target: A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
database_cross_reference: SYOExO:14974

public policy
type: Class
subclass of: exposure outcome
created by: cmattin
creation date: 2011-01-11T01:31:15Z
has_obo_namespace: exposure_outcome
id: ExO:0000082

exposure medium
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure event
definition: An exposure medium is a substance through which something else is transmitted or carried during an exposure.
created by: cmattin
creation date: 2011-01-11T01:33:44Z
has_obo_namespace: assay
id: ExO:0000083

Axiom
annotated source: exposure medium
annotated property: definition
annotated target: An exposure medium is a substance through which something else is transmitted or carried during an exposure.
database_cross_reference: sep:00037

commercial product
type: Class
subclass of: source
definition: The end result of a manufacturing process; anything that is produced.
created by: cmattin
creation date: 2011-01-12T12:14:24Z
has_obo_namespace: source
id: ExO:0000085

Axiom
annotated source: commercial product
annotated property: definition
annotated target: The end result of a manufacturing process; anything that is produced.
database_cross_reference: NCIT:C1514468

exposure intervention
type: Class
subclass of: exposure outcome
definition: The act or fact of interfering so as to modify.
created by: cmattin
creation date: 2011-01-12T01:34:34Z
has_obo_namespace: exposure_outcome
id: ExO:0000087

Axiom
annotated source: exposure intervention
annotated property: definition
annotated target: The act or fact of interfering so as to modify.
database_cross_reference: CTD:curators

spatial quality
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: exposure event
subclass of: Restriction
  on property: BFO_0000050
  some values from: source
subclass of: Restriction
  on property: BFO_0000050
  some values from: assay
definition: Of or relating to space or components within space.
created by: cmattin
creation date: 2011-01-10T04:20:11Z
has_obo_namespace: spatial_quality
id: ExO:0000088

Axiom
annotated source: spatial quality
annotated property: definition
annotated target: Of or relating to space or components within space.
database_cross_reference: CTD:curators

human attribute
type: Class
subclass of: human population
subclass of: human individual
subclass of: Restriction
  on property: BFO_0000050
  some values from: human individual
definition: An attribute describing some aspect of an individual or human population.
created by: cmattin
creation date: 2011-01-10T09:30:27Z
has_obo_namespace: human_attribute
id: ExO:0000089

Axiom
annotated source: human attribute
annotated property: definition
annotated target: An attribute describing some aspect of an individual or human population.
database_cross_reference: CTD:curators

method
type: Class
subclass of: Restriction
  on property: BFO_0000050
  some values from: assay
definition: The protocol for an assay.
created by: cmattin
creation date: 2011-06-08T03:47:29Z
has_obo_namespace: assay
id: ExO:0000090

Axiom
annotated source: method
annotated property: definition
annotated target: The protocol for an assay.
database_cross_reference: CTD:curators

residential environment stressor source
type: Class
subclass of: source
definition: Of, or relating to, the area in which an individual or population lives, primarily describing the dwelling or shelter used for housing and the location immediately surrounding it
created by: cgrondin
creation date: 2017-04-03T03:47:29Z
has_obo_namespace: source
id: ExO:0000091

environmental stressor source
type: Class
subclass of: source
definition: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://meshb.nlm.nih.gov/record/ui
has_obo_namespace: source
id: ExO:0000092

occupational stressor source
type: Class
subclass of: source
definition: The origination of a stressor from the location of the principal work or business of an individual.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
has_obo_namespace: source
has_related_synonym: occupation
id: ExO:0000093

medicinal stressor source
type: Class
subclass of: source
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: source
has_related_synonym: drug
has_related_synonym: medication
has_related_synonym: medicine
id: ExO:0000094

dietary stressor source
type: Class
subclass of: source
definition: The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.
created by: cgrondin
creation date: 2017-04-03T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: influencing_factor
has_related_synonym: diet
has_related_synonym: dietary
id: ExO:0000095

country
type: Class
subclass of: location
definition: A collective generic term that refers here to a wide variety of dependencies, areas of special sovereignty, uninhabited islands, and other entities in addition to the traditional countries or independent states.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp
has_obo_namespace: location
has_related_synonym: country code
id: ExO:0000096

province
type: Class
subclass of: country
definition: A region, district or division of a country; a tract; a portion a state, especially one remote from the capital.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: location
id: ExO:0000097

region
type: Class
subclass of: country
definition: An area or portion of something with more or less definite boundaries designed or specified according to some established biological, administrative, economic, demographic, etc. criteria.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: location
id: ExO:0000098

US State
type: Class
subclass of: country
definition: One of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: location
id: ExO:0000099

phenotype
type: Class
subclass of: biological response
definition: The assemblage of traits or outward appearance of an individual. It is the product of interactions between genes and between genes and the environment.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: biological_response
id: ExO:0000101

age
type: Class
subclass of: influencing factor
definition: How long something or someone has existed; elapsed time since birth.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: aged
has_related_synonym: chronological age
has_related_synonym: postnatal age
id: ExO:0000102

influencing factor
type: Class
subclass of: health status
definition: Other conditions with the power to have an effect on health status.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: health_status
has_related_synonym: Influence
id: ExO:0000103

alcohol consumption
type: Class
subclass of: influencing factor
definition: Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: influencing_factor
has_related_synonym: alcohol drinking
has_related_synonym: alcohol use
id: ExO:0000104

body mass index
type: Class
subclass of: influencing factor
definition: A general indicator of the body fat an individual is carrying based upon the ratio of weight to height.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_exact_synonym: BMI
has_obo_namespace: human_attribute
id: ExO:0000105

diet
type: Class
subclass of: influencing factor
definition: The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: influencing_factor
has_related_synonym: dietary
id: ExO:0000106

genotype
type: Class
subclass of: influencing factor
definition: The genetic constitution of an organism or cell, as distinct from its expressed features or phenotype.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: genetics
id: ExO:0000107

physical activity
type: Class
subclass of: influencing factor
definition: Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: influencing_factor
id: ExO:0000108

race
type: Class
subclass of: influencing factor
definition: An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: racial group
id: ExO:0000109

sex
type: Class
subclass of: influencing factor
definition: The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: gender
id: ExO:0000110

female
type: Class
subclass of: sex
definition: A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: girl
has_related_synonym: woman
id: ExO:0000111

male
type: Class
subclass of: sex
definition: A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: boy
has_related_synonym: man
id: ExO:0000112

smoking status
type: Class
subclass of: influencing factor
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: health_status
has_related_synonym: tobacco use
id: ExO:0000113

socioeconomic status
type: Class
subclass of: social characteristic
subclass of: influencing factor
definition: Characteristics of a person such as education and occupation, used to describe the person's position in stratification systems, access to services, etc.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: human_attribute
has_related_synonym: class
has_related_synonym: socioeconomic factors
id: ExO:0000114

current smoker
type: Class
subclass of: smoking status
disjoint with: former smoker
disjoint with: never smoker
disjoint with: non-smoker
definition: An adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes cigarettes. Includes daily smokers and non-daily smokers (also known as occasional smokers).
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_exact_synonym: Smoker
has_obo_namespace: exposure_receptor
id: ExO:0000115

former smoker
type: Class
subclass of: smoking status
definition: A person who was not smoking at the time of the interview but has smoked at least 100 cigarettes in their life.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_exact_synonym: Prior Smoker
has_obo_namespace: exposure_receptor
id: ExO:0000116

never smoker
type: Class
subclass of: smoking status
definition: A person who was not smoking at the time of the interview and has smoked less than 100 cigarettes in their life.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: non-smoker
id: ExO:0000117

non-smoker
type: Class
subclass of: smoking status
definition: A person who was not smoking at the time of the interview and has smoked less than 100 cigarettes in their life.
created by: cgrondin
creation date: 2017-04-06T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Never Smoker
id: ExO:0000118

children
type: Class
subclass of: human population
definition: Persons who are not yet adults. The specific cut-off age will vary by purpose.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: adolescent
has_related_synonym: child
has_related_synonym: schoolchildren
has_related_synonym: teen
has_related_synonym: teenager
has_related_synonym: toddler
id: ExO:0000119

cohort
type: Class
subclass of: human population
definition: A group of individuals, identified by a common characteristic.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000120

controls for disease or phenotype
type: Class
subclass of: human population
definition: Study subjects who serve as controls (i.e., lack the characteristics of a disease or phenotype) in a research study as compared to study subjects with a disease or phenotype as indicated.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000121

fetuses
type: Class
subclass of: human population
definition: An unborn or unhatched vertebrate in the later stages of development showing the main recognizable features of the mature being.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000122

infants or newborns
type: Class
subclass of: human population
definition: A young child between one month and two years of age or between birth and one month of age.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: neonate
has_related_synonym: newborn
id: ExO:0000123

military personnel
type: Class
subclass of: human population
definition: Persons including soldiers involved with the armed forces.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://meshb.nlm.nih.gov/record/ui
has_obo_namespace: exposure_receptor
id: ExO:0000124

mothers
type: Class
subclass of: human population
definition: A female parent.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: mother
id: ExO:0000125

pregnant females
type: Class
subclass of: human population
definition: Human females who are pregnant.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://meshb.nlm.nih.gov/record/ui
has_obo_namespace: exposure_receptor
has_related_synonym: Pregnant Women
id: ExO:0000126

study subjects
type: Class
subclass of: human population
definition: Persons who are observed, analyzed, examined, investigated, experimented upon, or/and treated in the course of a particular study.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp
has_obo_namespace: exposure_receptor
has_related_synonym: study subject
id: ExO:0000127

subjects with disease or phenotype
type: Class
subclass of: human population
definition: Study subjects with a disease or phenotype as indicated.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000128

subjects with gene influence
type: Class
subclass of: human population
definition: Study subjects who exhibit characteristics of a specific genotype in a research study.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000129

veterans
type: Class
subclass of: human population
definition: Former members of the armed services.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://meshb.nlm.nih.gov/record/ui
has_obo_namespace: exposure_receptor
id: ExO:0000130

workers
type: Class
subclass of: human population
definition: A person performing a job or service for another person or a business firm on a full- or part-time basis and who receives payment for this work.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: employee
has_related_synonym: employees
has_related_synonym: worker
id: ExO:0000131

African American
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Black
has_related_synonym: Haitian
has_related_synonym: Negro
id: ExO:0000132

Alaska Native
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes a person having origins in any indigenous people of Alaska and their descendants and who maintains tribal affiliation, or community or cultural attachment. The concept refers to population subgroups such as Eskimos, Aleuts, Inupiat, Yupik, Alutiiq, Egegik,and Pribilovian, Alaskan Athabascan, Tlingit, and Haida. The concept refers also to individuals who classify themselves as such.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Alaska Indian
has_related_synonym: Alaskan Athabascan
has_related_synonym: Aleut
has_related_synonym: Alutiq
has_related_synonym: Egegik
has_related_synonym: Eskimo
has_related_synonym: Haida
has_related_synonym: Inupiat
has_related_synonym: Pribilovian
has_related_synonym: Tlingit
has_related_synonym: Yupik
id: ExO:0000133

American Indian
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes a person having origins in one of the indigenous peoples of North America, who lived on the continent prior to the European colonization. The term includes individuals belonging to a large number of tribes, states, and ethnic groups, many of them still enduring as communities.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000134

Asian
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000135

Asian Indian
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in the original peoples of the Indian sub-continent.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Asian Indians
has_related_synonym: Indian
id: ExO:0000136

Central or South American
type: Class
subclass of: race
disjoint with: Other Race
definition: A person of Central or South American culture or origin.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000137

Chicano
type: Class
subclass of: race
disjoint with: Other Race
definition: A term sometimes used interchangeably with Mexican-American to denote an American citizen of Mexican decent. The term is a chosen identity of some Mexican-Americans in the United States.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
has_related_synonym: Mexican-American
id: ExO:0000138

Chinese
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of China.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000139

Cuban
type: Class
subclass of: race
disjoint with: Other Race
definition: A person of Cuban culture or origin, regardless of race.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Cuban-American
has_related_synonym: Hispanic
has_related_synonym: Latino
id: ExO:0000140

Cuban-American
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes a person from or of Cuba or an American citizen of Cuban descent.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Cuban
id: ExO:0000141

Dominican
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes the inhabitants of the Dominican Republic, a person from there, or their descendants elsewhere.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000142

Filipino
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of the Philippine Islands.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000143

Guamanian
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes inhabitants of Guam, an island in the North Pacific Ocean, about three-quarters of the way from Hawaii to the Philippines, south of the Northern Mariana Islands.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000144

Hispanic
type: Class
subclass of: race
disjoint with: Other Race
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Central American
has_related_synonym: Cuban
has_related_synonym: Latino
has_related_synonym: Mexican
has_related_synonym: Puerto Rican
has_related_synonym: South American
has_related_synonym: Spanish origin
id: ExO:0000145

Inuit
type: Class
subclass of: race
disjoint with: Other Race
definition: A general term for a group of culturally similar indigenous peoples inhabiting the Arctic regions of Canada, Greenland, Russia and the United States. In Alaska, the term Eskimo is commonly used, because it includes both Yupik and Inupiat, while Inuit is not accepted as a collective term. In Canada and Greenland, the term Eskimo has fallen out of favor, as it is considered pejorative by the natives and has been replaced by the term Inuit.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Eskimo
id: ExO:0000146

Japanese
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of Japan.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000147

Korean
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of Korea.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000148

Latino
type: Class
subclass of: race
disjoint with: Other Race
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Hispanic Spanish origin
has_related_synonym: Spanish origin
id: ExO:0000149

Mexican
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes a person from or of Mexico.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Hispanic
id: ExO:0000150

Mexican-American
type: Class
subclass of: race
disjoint with: Other Race
definition: Denotes an american citizen of Mexican descent.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000151

Native Hawaiian
type: Class
subclass of: race
disjoint with: Other Race
definition: A person having origins in any of the original peoples of Hawaii.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Hawaiian
id: ExO:0000152

Other Race
type: Class
subclass of: race
disjoint with: Pacific Islander
disjoint with: Puerto Rican
disjoint with: Samoan
disjoint with: Vietnamese
disjoint with: White
definition: A person of non-specified racial, cultural, or geographic origins.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
has_related_synonym: Other
id: ExO:0000153

Pacific Islander
type: Class
subclass of: race
definition: A person having origins in the original peoples of the Pacific Islands, but not Guam, Hawaii, the Mariana Islands or Samoa.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Other Pacific Islander
id: ExO:0000154

Puerto Rican
type: Class
subclass of: race
definition: A person of Puerto Rican descent.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000155

Samoan
type: Class
subclass of: race
definition: A person having origins in any of the original peoples of Samoa.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
id: ExO:0000156

Vietnamese
type: Class
subclass of: race
definition: A person having origins in any of the original peoples of Vietnam.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
has_obo_namespace: exposure_receptor
id: ExO:0000157

White
type: Class
subclass of: race
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
created by: cgrondin
creation date: 2017-04-07T03:47:29Z
database_cross_reference: https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf
has_obo_namespace: exposure_receptor
has_related_synonym: Caucasian
has_related_synonym: Caucasians
has_related_synonym: Caucasoid
has_related_synonym: Occidental
has_related_synonym: Whites
id: ExO:0000158

maternal
type: Class
subclass of: exposure route
definition: A route by which an exposure to a pregnant female causes an outcome in the fetus that might be observed long after birth
created by: cgrondin
creation date: 2020-08-17T03:47:29Z
has_obo_namespace: route
id: ExO:0000159

ambient environment route
type: Class
subclass of: exposure route
definition: An exposure route in which a subject or sample comes in contact with a stressor present in the subject or sample's direct surroundings.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:10Z
has_obo_namespace: route
id: ExO:0000160

Axiom
annotated source: ambient environment route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor present in the subject or sample's direct surroundings.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

ambient acquatic environment route
type: Class
subclass of: ambient environment route
definition: An ambient environment route in which the surroundings are water.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:11Z
has_obo_namespace: route
id: ExO:0000161

Axiom
annotated source: ambient acquatic environment route
annotated property: definition
annotated target: An ambient environment route in which the surroundings are water.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

ambient terrestrial environment route
type: Class
subclass of: ambient environment route
definition: An ambient environment in which the surroundings are terrestrial.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:12Z
has_obo_namespace: route
id: ExO:0000162

Axiom
annotated source: ambient terrestrial environment route
annotated property: definition
annotated target: An ambient environment in which the surroundings are terrestrial.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

passive inhalation of the ambient environment route
type: Class
subclass of: inhalation route
subclass of: ambient terrestrial environment route
definition: An exposure route in which a subject or sample comes in contact with a stressor by breathing the ambient air containing this stressor.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:14Z
has_obo_namespace: route
id: ExO:0000163

Axiom
annotated source: passive inhalation of the ambient environment route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor by breathing the ambient air containing this stressor.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

active inhalation route
type: Class
subclass of: inhalation route
definition: An exposure route in which a subject or sample comes in contact with a stressor by purposely breathing or inhaling the stressor or substance containing the stressor.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:15Z
has_obo_namespace: route
id: ExO:0000164

Axiom
annotated source: active inhalation route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor by purposely breathing or inhaling the stressor or substance containing the stressor.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

gastrointestinal tract route
type: Class
subclass of: exposure route
definition: An exposure route in which a subject or sample comes in contact with a stressor in the subject's gastrointestinal tract.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:17Z
has_obo_namespace: route
id: ExO:0000165

Axiom
annotated source: gastrointestinal tract route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor in the subject's gastrointestinal tract.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

gavage route
type: Class
subclass of: gastrointestinal tract route
definition: An exposure route in which a subject or sample comes in contact with a stressor that was directly administered into the stomach.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-25T09:39:19Z
has_obo_namespace: route
id: ExO:0000166

Axiom
annotated source: gavage route
annotated property: definition
annotated target: An exposure route in which a subject or sample comes in contact with a stressor that was directly administered into the stomach.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

sustained exposure
type: Class
subclass of: exposure regimen
definition: An exposure in which the contact with the stressor is uninterrupted over an extended period of time.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:10Z
has_exact_synonym: continuous exposure
has_obo_namespace: source
id: ExO:0000167

Axiom
annotated source: sustained exposure
annotated property: definition
annotated target: An exposure in which the contact with the stressor is uninterrupted over an extended period of time.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

static exposure
type: Class
subclass of: sustained exposure
definition: A sustained chemical exposure in which the exposed subject or sample is in a non-flowing, stagnant environment with the stressor.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:11Z
has_obo_namespace: source
id: ExO:0000168

Axiom
annotated source: static exposure
annotated property: definition
annotated target: A sustained chemical exposure in which the exposed subject or sample is in a non-flowing, stagnant environment with the stressor.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

static renewal exposure
type: Class
subclass of: sustained exposure
definition: A sustained chemical exposure in which the exposed subject or sample is in an environment with the stressor is refreshed or renewed periodically.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:12Z
has_obo_namespace: source
id: ExO:0000169

Axiom
annotated source: static renewal exposure
annotated property: definition
annotated target: A sustained chemical exposure in which the exposed subject or sample is in an environment with the stressor is refreshed or renewed periodically.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

dynamic exposure
type: Class
subclass of: sustained exposure
definition: A sustained chemical exposure in which the exposed subject or sample is in an environment where the stressor is constantly refreshed or renewed.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:13Z
has_exact_synonym: flow through exposure
has_obo_namespace: source
id: ExO:0000170

Axiom
annotated source: dynamic exposure
annotated property: definition
annotated target: A sustained chemical exposure in which the exposed subject or sample is in an environment where the stressor is constantly refreshed or renewed.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

repeated exposure
type: Class
subclass of: exposure regimen
definition: An exposure in which the contact with the stressor occurs more than once over a period of time, at intervals.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:14Z
has_obo_namespace: source
id: ExO:0000171

Axiom
annotated source: repeated exposure
annotated property: definition
annotated target: An exposure in which the contact with the stressor occurs more than once over a period of time, at intervals.
database_cross_reference: https://orcid.org/0000-0002-4142-7153

exposure regimen
type: Class
definition: The pattern or schedule of an exposure event, including dose, frequency, and duration.
created by: https://orcid.org/0000-0002-4142-7153
creation date: 2025-08-26T09:39:Z
has_obo_namespace: exposure_event
id: ExO:0000172

Axiom
annotated source: exposure regimen
annotated property: definition
annotated target: The pattern or schedule of an exposure event, including dose, frequency, and duration.
database_cross_reference: https://orcid.org/0000-0002-4142-7153