1 00:00:01,100 --> 00:00:04,519 covering the week's top textbooks like 2 00:00:04,519 --> 00:00:04,529 covering the week's top textbooks like 3 00:00:04,529 --> 00:00:08,210 covering the week's top textbooks like Linux bias not to create false hope but 4 00:00:08,210 --> 00:00:08,220 Linux bias not to create false hope but 5 00:00:08,220 --> 00:00:09,890 Linux bias not to create false hope but this is too huge not to mention 6 00:00:09,890 --> 00:00:09,900 this is too huge not to mention 7 00:00:09,900 --> 00:00:12,230 this is too huge not to mention scientists at Cardiff University have 8 00:00:12,230 --> 00:00:12,240 scientists at Cardiff University have 9 00:00:12,240 --> 00:00:14,089 scientists at Cardiff University have discovered a part of our immune system 10 00:00:14,089 --> 00:00:14,099 discovered a part of our immune system 11 00:00:14,099 --> 00:00:17,359 discovered a part of our immune system that can kill prostate breast lung and 12 00:00:17,359 --> 00:00:17,369 that can kill prostate breast lung and 13 00:00:17,369 --> 00:00:21,320 that can kill prostate breast lung and other cancers in lab tests the findings 14 00:00:21,320 --> 00:00:21,330 other cancers in lab tests the findings 15 00:00:21,330 --> 00:00:24,740 other cancers in lab tests the findings published in Nature immunology have not 16 00:00:24,740 --> 00:00:24,750 published in Nature immunology have not 17 00:00:24,750 --> 00:00:27,050 published in Nature immunology have not yet been tested in patients but the 18 00:00:27,050 --> 00:00:27,060 yet been tested in patients but the 19 00:00:27,060 --> 00:00:29,990 yet been tested in patients but the researchers say that they have enormous 20 00:00:29,990 --> 00:00:30,000 researchers say that they have enormous 21 00:00:30,000 --> 00:00:33,740 researchers say that they have enormous potential experts are saying that 22 00:00:33,740 --> 00:00:33,750 potential experts are saying that 23 00:00:33,750 --> 00:00:36,950 potential experts are saying that although the work was still at an early 24 00:00:36,950 --> 00:00:36,960 although the work was still at an early 25 00:00:36,960 --> 00:00:41,000 although the work was still at an early stage it is very exciting our immune 26 00:00:41,000 --> 00:00:41,010 stage it is very exciting our immune 27 00:00:41,010 --> 00:00:44,000 stage it is very exciting our immune system is our body's natural defense 28 00:00:44,000 --> 00:00:44,010 system is our body's natural defense 29 00:00:44,010 --> 00:00:46,220 system is our body's natural defense against infection but it also attacks 30 00:00:46,220 --> 00:00:46,230 against infection but it also attacks 31 00:00:46,230 --> 00:00:48,860 against infection but it also attacks cancerous cells the scientists were 32 00:00:48,860 --> 00:00:48,870 cancerous cells the scientists were 33 00:00:48,870 --> 00:00:51,650 cancerous cells the scientists were looking for unconventional and 34 00:00:51,650 --> 00:00:51,660 looking for unconventional and 35 00:00:51,660 --> 00:00:53,930 looking for unconventional and previously undiscovered ways the immune 36 00:00:53,930 --> 00:00:53,940 previously undiscovered ways the immune 37 00:00:53,940 --> 00:00:57,350 previously undiscovered ways the immune system naturally attacks tumors what 38 00:00:57,350 --> 00:00:57,360 system naturally attacks tumors what 39 00:00:57,360 --> 00:00:59,750 system naturally attacks tumors what they found was a t-cell inside people's 40 00:00:59,750 --> 00:00:59,760 they found was a t-cell inside people's 41 00:00:59,760 --> 00:01:02,209 they found was a t-cell inside people's blood this is an immune cell that can 42 00:01:02,209 --> 00:01:02,219 blood this is an immune cell that can 43 00:01:02,219 --> 00:01:04,340 blood this is an immune cell that can scan the body to assess whether there is 44 00:01:04,340 --> 00:01:04,350 scan the body to assess whether there is 45 00:01:04,350 --> 00:01:07,070 scan the body to assess whether there is a threat that needs to be eliminated the 46 00:01:07,070 --> 00:01:07,080 a threat that needs to be eliminated the 47 00:01:07,080 --> 00:01:09,740 a threat that needs to be eliminated the difference is that the one in particular 48 00:01:09,740 --> 00:01:09,750 difference is that the one in particular 49 00:01:09,750 --> 00:01:11,780 difference is that the one in particular that they discovered can seemingly 50 00:01:11,780 --> 00:01:11,790 that they discovered can seemingly 51 00:01:11,790 --> 00:01:15,789 that they discovered can seemingly attack a wide range of cancers 52 00:01:15,789 --> 00:01:15,799 attack a wide range of cancers 53 00:01:15,799 --> 00:01:19,370 attack a wide range of cancers researcher professor Andrew Sewall says 54 00:01:19,370 --> 00:01:19,380 researcher professor Andrew Sewall says 55 00:01:19,380 --> 00:01:22,249 researcher professor Andrew Sewall says quote there is a chance to treat every 56 00:01:22,249 --> 00:01:22,259 quote there is a chance to treat every 57 00:01:22,259 --> 00:01:24,710 quote there is a chance to treat every patient previously nobody believed this 58 00:01:24,710 --> 00:01:24,720 patient previously nobody believed this 59 00:01:24,720 --> 00:01:27,440 patient previously nobody believed this could be possible it raises the prospect 60 00:01:27,440 --> 00:01:27,450 could be possible it raises the prospect 61 00:01:27,450 --> 00:01:30,230 could be possible it raises the prospect of a one-size-fits-all cancer treatment 62 00:01:30,230 --> 00:01:30,240 of a one-size-fits-all cancer treatment 63 00:01:30,240 --> 00:01:32,660 of a one-size-fits-all cancer treatment a single type of t-cell that could be 64 00:01:32,660 --> 00:01:32,670 a single type of t-cell that could be 65 00:01:32,670 --> 00:01:34,940 a single type of t-cell that could be capable of destroying many different 66 00:01:34,940 --> 00:01:34,950 capable of destroying many different 67 00:01:34,950 --> 00:01:37,249 capable of destroying many different types of cancers across the population 68 00:01:37,249 --> 00:01:37,259 types of cancers across the population 69 00:01:37,259 --> 00:01:41,390 types of cancers across the population end quote the discovered t-cell was able 70 00:01:41,390 --> 00:01:41,400 end quote the discovered t-cell was able 71 00:01:41,400 --> 00:01:43,219 end quote the discovered t-cell was able to kill a wide range of cancerous cells 72 00:01:43,219 --> 00:01:43,229 to kill a wide range of cancerous cells 73 00:01:43,229 --> 00:01:46,910 to kill a wide range of cancerous cells in in the lab including lung skin blood 74 00:01:46,910 --> 00:01:46,920 in in the lab including lung skin blood 75 00:01:46,920 --> 00:01:51,319 in in the lab including lung skin blood colon breast bone prostate ovarian 76 00:01:51,319 --> 00:01:51,329 colon breast bone prostate ovarian 77 00:01:51,329 --> 00:01:54,639 colon breast bone prostate ovarian kidney and cervical cancer cells Wow 78 00:01:54,639 --> 00:01:54,649 kidney and cervical cancer cells Wow 79 00:01:54,649 --> 00:01:57,469 kidney and cervical cancer cells Wow crucially it left normal tissues 80 00:01:57,469 --> 00:01:57,479 crucially it left normal tissues 81 00:01:57,479 --> 00:02:01,819 crucially it left normal tissues untouched exactly how it does all this 82 00:02:01,819 --> 00:02:01,829 untouched exactly how it does all this 83 00:02:01,829 --> 00:02:05,630 untouched exactly how it does all this is still being explored the idea is that 84 00:02:05,630 --> 00:02:05,640 is still being explored the idea is that 85 00:02:05,640 --> 00:02:07,819 is still being explored the idea is that a blood sample would be taken from a 86 00:02:07,819 --> 00:02:07,829 a blood sample would be taken from a 87 00:02:07,829 --> 00:02:11,440 a blood sample would be taken from a cancer patient the T cells in the sample 88 00:02:11,440 --> 00:02:11,450 cancer patient the T cells in the sample 89 00:02:11,450 --> 00:02:13,699 cancer patient the T cells in the sample would be extracted 90 00:02:13,699 --> 00:02:13,709 would be extracted 91 00:02:13,709 --> 00:02:15,949 would be extracted and genetically modified so that they 92 00:02:15,949 --> 00:02:15,959 and genetically modified so that they 93 00:02:15,959 --> 00:02:18,440 and genetically modified so that they were they were reprogrammed to make the 94 00:02:18,440 --> 00:02:18,450 were they were reprogrammed to make the 95 00:02:18,450 --> 00:02:21,530 were they were reprogrammed to make the cancer finding receptor the upgraded 96 00:02:21,530 --> 00:02:21,540 cancer finding receptor the upgraded 97 00:02:21,540 --> 00:02:23,959 cancer finding receptor the upgraded cells would be grown in vast quantities 98 00:02:23,959 --> 00:02:23,969 cells would be grown in vast quantities 99 00:02:23,969 --> 00:02:26,479 cells would be grown in vast quantities in the laboratory and then put back into 100 00:02:26,479 --> 00:02:26,489 in the laboratory and then put back into 101 00:02:26,489 --> 00:02:29,899 in the laboratory and then put back into the patient Daniel Davis a professor of 102 00:02:29,899 --> 00:02:29,909 the patient Daniel Davis a professor of 103 00:02:29,909 --> 00:02:31,339 the patient Daniel Davis a professor of immunology at the University of 104 00:02:31,339 --> 00:02:31,349 immunology at the University of 105 00:02:31,349 --> 00:02:34,039 immunology at the University of Manchester said quote at the moment this 106 00:02:34,039 --> 00:02:34,049 Manchester said quote at the moment this 107 00:02:34,049 --> 00:02:37,670 Manchester said quote at the moment this is very basic research and not close for 108 00:02:37,670 --> 00:02:37,680 is very basic research and not close for 109 00:02:37,680 --> 00:02:39,920 is very basic research and not close for two actual medicines for patients there 110 00:02:39,920 --> 00:02:39,930 two actual medicines for patients there 111 00:02:39,930 --> 00:02:42,050 two actual medicines for patients there is no question that is a very exciting 112 00:02:42,050 --> 00:02:42,060 is no question that is a very exciting 113 00:02:42,060 --> 00:02:44,569 is no question that is a very exciting discovery both for advancing our basic 114 00:02:44,569 --> 00:02:44,579 discovery both for advancing our basic 115 00:02:44,579 --> 00:02:46,339 discovery both for advancing our basic knowledge about the immune system and 116 00:02:46,339 --> 00:02:46,349 knowledge about the immune system and 117 00:02:46,349 --> 00:02:48,979 knowledge about the immune system and the possibility of future new medicines 118 00:02:48,979 --> 00:02:48,989 the possibility of future new medicines 119 00:02:48,989 --> 00:02:52,789 the possibility of future new medicines and quote more safety checks will be 120 00:02:52,789 --> 00:02:52,799 and quote more safety checks will be 121 00:02:52,799 --> 00:02:56,770 and quote more safety checks will be needed before human trials can begin I 122 00:02:56,770 --> 00:02:56,780 needed before human trials can begin I 123 00:02:56,780 --> 00:02:59,659 needed before human trials can begin I like this this isn't necessarily a text 124 00:02:59,659 --> 00:02:59,669 like this this isn't necessarily a text 125 00:02:59,669 --> 00:03:04,879 like this this isn't necessarily a text story but it's a human interest story 126 00:03:04,879 --> 00:03:04,889 story but it's a human interest story 127 00:03:04,889 --> 00:03:08,479 story but it's a human interest story that is here because of tech yeah the 128 00:03:08,479 --> 00:03:08,489 that is here because of tech yeah the 129 00:03:08,489 --> 00:03:10,129 that is here because of tech yeah the advancements that we have made in 130 00:03:10,129 --> 00:03:10,139 advancements that we have made in 131 00:03:10,139 --> 00:03:12,470 advancements that we have made in science to be able to get to the point 132 00:03:12,470 --> 00:03:12,480 science to be able to get to the point 133 00:03:12,480 --> 00:03:15,500 science to be able to get to the point where it's like what else is there let's 134 00:03:15,500 --> 00:03:15,510 where it's like what else is there let's 135 00:03:15,510 --> 00:03:16,940 where it's like what else is there let's explore the body even further let's 136 00:03:16,940 --> 00:03:16,950 explore the body even further let's 137 00:03:16,950 --> 00:03:18,920 explore the body even further let's alter this cell and see what happens 138 00:03:18,920 --> 00:03:18,930 alter this cell and see what happens 139 00:03:18,930 --> 00:03:21,500 alter this cell and see what happens yeah and boom suddenly we're going is 140 00:03:21,500 --> 00:03:21,510 yeah and boom suddenly we're going is 141 00:03:21,510 --> 00:03:25,879 yeah and boom suddenly we're going is this it that is so cool exactly the 142 00:03:25,879 --> 00:03:25,889 this it that is so cool exactly the 143 00:03:25,889 --> 00:03:27,619 this it that is so cool exactly the truth of the matter is right now cancer 144 00:03:27,619 --> 00:03:27,629 truth of the matter is right now cancer 145 00:03:27,629 --> 00:03:30,879 truth of the matter is right now cancer treatments are just they seem so 146 00:03:30,879 --> 00:03:30,889 treatments are just they seem so 147 00:03:30,889 --> 00:03:33,050 treatments are just they seem so barbaric right now they're life-saving 148 00:03:33,050 --> 00:03:33,060 barbaric right now they're life-saving 149 00:03:33,060 --> 00:03:35,509 barbaric right now they're life-saving but they're super intrusive so I mean 150 00:03:35,509 --> 00:03:35,519 but they're super intrusive so I mean 151 00:03:35,519 --> 00:03:38,509 but they're super intrusive so I mean you know the chemotherapy surgery the 152 00:03:38,509 --> 00:03:38,519 you know the chemotherapy surgery the 153 00:03:38,519 --> 00:03:40,670 you know the chemotherapy surgery the things that that are just really 154 00:03:40,670 --> 00:03:40,680 things that that are just really 155 00:03:40,680 --> 00:03:42,429 things that that are just really radiation things that are really 156 00:03:42,429 --> 00:03:42,439 radiation things that are really 157 00:03:42,439 --> 00:03:44,960 radiation things that are really detrimental to the human body just to 158 00:03:44,960 --> 00:03:44,970 detrimental to the human body just to 159 00:03:44,970 --> 00:03:48,520 detrimental to the human body just to keep it alive you can have an immune 160 00:03:48,520 --> 00:03:48,530 keep it alive you can have an immune 161 00:03:48,530 --> 00:03:53,229 keep it alive you can have an immune response against cancer that that just 162 00:03:53,229 --> 00:03:53,239 response against cancer that that just 163 00:03:53,239 --> 00:03:56,619 response against cancer that that just annihilates any trace of it I just 164 00:03:56,619 --> 00:03:56,629 annihilates any trace of it I just 165 00:03:56,629 --> 00:04:00,140 annihilates any trace of it I just cannot wait I don't really like does 166 00:04:00,140 --> 00:04:00,150 cannot wait I don't really like does 167 00:04:00,150 --> 00:04:01,939 cannot wait I don't really like does anyone else feel that like excitement 168 00:04:01,939 --> 00:04:01,949 anyone else feel that like excitement 169 00:04:01,949 --> 00:04:04,580 anyone else feel that like excitement and the anticipation like could it be 170 00:04:04,580 --> 00:04:04,590 and the anticipation like could it be 171 00:04:04,590 --> 00:04:08,569 and the anticipation like could it be like could that be possible and all 172 00:04:08,569 --> 00:04:08,579 like could that be possible and all 173 00:04:08,579 --> 00:04:10,759 like could that be possible and all they're doing is taking the t-cell that 174 00:04:10,759 --> 00:04:10,769 they're doing is taking the t-cell that 175 00:04:10,769 --> 00:04:13,280 they're doing is taking the t-cell that you already produce out and they're just 176 00:04:13,280 --> 00:04:13,290 you already produce out and they're just 177 00:04:13,290 --> 00:04:15,020 you already produce out and they're just replicating it like they're kind of 178 00:04:15,020 --> 00:04:15,030 replicating it like they're kind of 179 00:04:15,030 --> 00:04:16,879 replicating it like they're kind of growing more on their own they're 180 00:04:16,879 --> 00:04:16,889 growing more on their own they're 181 00:04:16,889 --> 00:04:18,469 growing more on their own they're altering it to put in the receptor to 182 00:04:18,469 --> 00:04:18,479 altering it to put in the receptor to 183 00:04:18,479 --> 00:04:20,749 altering it to put in the receptor to find the cancer cells so that's a bit of 184 00:04:20,749 --> 00:04:20,759 find the cancer cells so that's a bit of 185 00:04:20,759 --> 00:04:22,580 find the cancer cells so that's a bit of a genetic modification and then they're 186 00:04:22,580 --> 00:04:22,590 a genetic modification and then they're 187 00:04:22,590 --> 00:04:25,370 a genetic modification and then they're culturing more so there can't be adverse 188 00:04:25,370 --> 00:04:25,380 culturing more so there can't be adverse 189 00:04:25,380 --> 00:04:26,720 culturing more so there can't be adverse reactions because 190 00:04:26,720 --> 00:04:26,730 reactions because 191 00:04:26,730 --> 00:04:30,290 reactions because your own sure I mean I don't understand 192 00:04:30,290 --> 00:04:30,300 your own sure I mean I don't understand 193 00:04:30,300 --> 00:04:31,700 your own sure I mean I don't understand the science Ike yeah pretend to 194 00:04:31,700 --> 00:04:31,710 the science Ike yeah pretend to 195 00:04:31,710 --> 00:04:34,010 the science Ike yeah pretend to understand the science but I know there 196 00:04:34,010 --> 00:04:34,020 understand the science but I know there 197 00:04:34,020 --> 00:04:36,970 understand the science but I know there was a time in our history when 198 00:04:36,970 --> 00:04:36,980 was a time in our history when 199 00:04:36,980 --> 00:04:40,400 was a time in our history when penicillin didn't exist and when and 200 00:04:40,400 --> 00:04:40,410 penicillin didn't exist and when and 201 00:04:40,410 --> 00:04:43,730 penicillin didn't exist and when and when it was discovered if you will that 202 00:04:43,730 --> 00:04:43,740 when it was discovered if you will that 203 00:04:43,740 --> 00:04:44,480 when it was discovered if you will that was a mistake 204 00:04:44,480 --> 00:04:44,490 was a mistake 205 00:04:44,490 --> 00:04:49,070 was a mistake yeah but so so when it was accidentally 206 00:04:49,070 --> 00:04:49,080 yeah but so so when it was accidentally 207 00:04:49,080 --> 00:04:53,180 yeah but so so when it was accidentally discovered how earth-shatteringly like 208 00:04:53,180 --> 00:04:53,190 discovered how earth-shatteringly like 209 00:04:53,190 --> 00:04:56,000 discovered how earth-shatteringly like how many lives were saved how many lives 210 00:04:56,000 --> 00:04:56,010 how many lives were saved how many lives 211 00:04:56,010 --> 00:04:58,250 how many lives were saved how many lives were improved because of it it's you 212 00:04:58,250 --> 00:04:58,260 were improved because of it it's you 213 00:04:58,260 --> 00:04:59,450 were improved because of it it's you know what I was having a conversation 214 00:04:59,450 --> 00:04:59,460 know what I was having a conversation 215 00:04:59,460 --> 00:05:01,940 know what I was having a conversation with one of my clients the other day and 216 00:05:01,940 --> 00:05:01,950 with one of my clients the other day and 217 00:05:01,950 --> 00:05:03,740 with one of my clients the other day and her older siblings were born before 218 00:05:03,740 --> 00:05:03,750 her older siblings were born before 219 00:05:03,750 --> 00:05:07,490 her older siblings were born before penicillin oh wow he said the reason I'm 220 00:05:07,490 --> 00:05:07,500 penicillin oh wow he said the reason I'm 221 00:05:07,500 --> 00:05:10,370 penicillin oh wow he said the reason I'm not deaf is because penicillin existed 222 00:05:10,370 --> 00:05:10,380 not deaf is because penicillin existed 223 00:05:10,380 --> 00:05:13,070 not deaf is because penicillin existed for me and not for my brothers Wow right 224 00:05:13,070 --> 00:05:13,080 for me and not for my brothers Wow right 225 00:05:13,080 --> 00:05:15,050 for me and not for my brothers Wow right so heartbreaking right yet at the same 226 00:05:15,050 --> 00:05:15,060 so heartbreaking right yet at the same 227 00:05:15,060 --> 00:05:17,690 so heartbreaking right yet at the same time it's like dawn of a new era 228 00:05:17,690 --> 00:05:17,700 time it's like dawn of a new era 229 00:05:17,700 --> 00:05:21,050 time it's like dawn of a new era yeah right it's very cool so are we at 230 00:05:21,050 --> 00:05:21,060 yeah right it's very cool so are we at 231 00:05:21,060 --> 00:05:23,240 yeah right it's very cool so are we at that point with cancer I don't think we 232 00:05:23,240 --> 00:05:23,250 that point with cancer I don't think we 233 00:05:23,250 --> 00:05:26,000 that point with cancer I don't think we are but I'm hopeful I'm like I'm so 234 00:05:26,000 --> 00:05:26,010 are but I'm hopeful I'm like I'm so 235 00:05:26,010 --> 00:05:29,180 are but I'm hopeful I'm like I'm so hopeful in humanity and and our our 236 00:05:29,180 --> 00:05:29,190 hopeful in humanity and and our our 237 00:05:29,190 --> 00:05:32,270 hopeful in humanity and and our our ability to accomplish that because I 238 00:05:32,270 --> 00:05:32,280 ability to accomplish that because I 239 00:05:32,280 --> 00:05:46,900 ability to accomplish that because I just want that 240 00:05:46,900 --> 00:05:46,910 241 00:05:46,910 --> 00:05:49,959 [Music]