identifier: METPO:2000004
label: builds base from
definition: An OBJECT_PROPERTY relating an organism to a chemical substrate from which
  the organism produces an alkaline metabolite, raising medium pH.
definition_source: PMID:21413255
trait_category: METABOLISM
term_kind: OBJECT_PROPERTY
mapping_status: REVIEWED
parent_traits:
- METPO:2000001
domain: https://w3id.org/metpo/1000525
range_: http://purl.obolibrary.org/obo/CHEBI_24431
evidence:
- reference: PMID:21413255
  snippet: alkaline
  notes: Microbial-physiology reference supports 'builds base from' as a canonical
    predicate composed with a CHEBI-class chemical object at assertion time.
curation_history:
- timestamp: '2026-05-05T01:35:46.951600+00:00'
  curator: seed_from_metpo
  action: SEEDED_FROM_METPO
  changes: imported from data/raw/metpo.owl (OBJECT_PROPERTY)
  llm_assisted: false
- timestamp: '2026-05-10T00:00:00-07:00'
  curator: codex
  action: DEPRECATED_PROPERTY_RECORD
  changes: Deprecated generic biochemical conversion or activity relation carrier;
    later replacement should use more specific trait records that combine the relation
    with the substrate, product, enzyme or activity target, assay context, growth
    condition, or other entity.
  llm_assisted: true
- timestamp: '2026-05-16T08:50:00-07:00'
  curator: claude
  action: UNDEPRECATED_AS_COMPOSITION_PRIMITIVE
  changes: 'Restored from DEPRECATED to REVIEWED under the predicate+class composition
    pattern (intended use: <organism> + this predicate + CHEBI chemical class). Added
    DOI/PMID-backed definition, evidence, and explicit domain/range slots.'
  llm_assisted: true
- timestamp: '2026-06-17T04:09:44Z'
  curator: claude
  action: REMOVE_REDUNDANT_SYNONYM
  changes: Removed 1 synonym(s) whose text duplicated the label (seeder redundancy;
    no information lost).
  llm_assisted: true