identifier: traitmech:000182
label: citrate fermentation
definition: A fermentation in which citrate is the primary fermentable substrate.
definition_source: DOI:10.1128/JB.183.18.5248-5256.2001
trait_category: METABOLISM
term_kind: CLASS
mapping_status: PROPOSED
parent_traits:
- METPO:1002005
evidence:
- reference: DOI:10.1128/JB.183.18.5248-5256.2001
  snippet: Klebsiella pneumoniae is able to grow anaerobically with citrate as a sole
    carbon and energy source by a fermentative pathway
  notes: Meyer et al. provide direct Klebsiella pneumoniae evidence for anaerobic
    growth on citrate through a fermentative pathway.
- reference: DOI:10.1186/1471-2180-9-168
  snippet: Not all, but nearly half of the K. pneumoniae clinical isolates carry the
    genes responsible for anaerobic growth on citrate.
  notes: Chen et al. found citrate-growth gene clusters in clinical K. pneumoniae
    isolates, supporting K. pneumoniae as a canonical citrate fermenter with strain-level
    variation.
canonical_examples:
- taxon_id: NCBITaxon:573
  taxon_label: Klebsiella pneumoniae
  note: Chen et al. and Meyer et al. both studied anaerobic citrate fermentation in
    K. pneumoniae strains.
  reference: DOI:10.1186/1471-2180-9-168
discussions:
- discussion_id: citrate-fermentation-xref-gap
  prompt: Resolve an exact external ontology class for citrate fermentation before
    adding a TraitRecord xref.
  kind: CURATION_TODO
  status: OPEN
  rationale: No exact GO or external metabolism class was resolved for anaerobic citrate
    fermentation; generic citrate metabolic process terms, citrate lyase or transporter
    molecular functions, and citrate-test assay terms are shifted relative to this
    pathway-scoped fermentation class.
  posed_by: codex
  posed_date: '2026-09-14'
curation_history:
- timestamp: '2026-09-14T04:09:24Z'
  curator: codex
  action: MINTED_TRAITMECH_ID
  changes: Minted citrate fermentation as a DOI-backed TraitRecord after a repository-wide
    duplicate review covering ignored and hidden files; METPO has no exact anaerobic
    citrate fermentation class yet and the placeholder is reserved in proposals/metpo_traitmech_v59.
  llm_assisted: true
- timestamp: '2026-09-14T04:38:10Z'
  curator: codex
  action: CURATION_REVIEW_REVISION
  changes: 'Resolved PR #894 review issue #897 by narrowing the minted record from
    citrate utilization to pathway-scoped citrate fermentation.'
  llm_assisted: true