identifier: METPO:2000301
label: enzyme activity analyzed
definition: An OBJECT_PROPERTY relating an organism to an enzyme (material
  entity) whose catalytic activity has been experimentally assayed for that
  organism. Intended use is predicate + class composition at assertion time
  with a METPO enzyme class (METPO:1000527 or its subclass) as the object.
definition_source: PMID:21413255
trait_category: METABOLISM
term_kind: OBJECT_PROPERTY
mapping_status: REVIEWED
synonyms:
- synonym_text: Physiology and metabolism.enzymes.[].activity
  synonym_type: RELATED_SYNONYM
  source: metpo.owl
domain: https://w3id.org/metpo/1000525
range_: https://w3id.org/metpo/1000527
evidence:
- reference: PMID:21413255
  snippet: enzyme activity
  notes: Microbial-physiology reference supports 'enzyme activity analyzed' as
    a canonical predicate relating an organism to an enzyme/activity class,
    composed at assertion time.
curation_history:
- timestamp: '2026-05-05T01:35:46.990561+00:00'
  curator: seed_from_metpo
  action: SEEDED_FROM_METPO
  changes: imported from data/raw/metpo.owl (OBJECT_PROPERTY)
  llm_assisted: false
- timestamp: '2026-05-10T00:00:00-07:00'
  curator: codex
  action: DEPRECATED_PROPERTY_RECORD
  changes: Deprecated generic metabolism relation carrier; later replacement should
    use more specific trait records that combine the relation with the chemical, phenotype,
    quality, compartment, enzyme or activity target, growth context, measurement,
    or other entity.
  llm_assisted: true
- timestamp: '2026-05-16T08:50:00-07:00'
  curator: claude
  action: UNDEPRECATED_AS_COMPOSITION_PRIMITIVE
  changes: 'Restored from DEPRECATED to REVIEWED under the predicate+class composition
    pattern (intended use: <organism> + this predicate + CHEBI chemical class). Added
    DOI/PMID-backed definition, evidence, and explicit domain/range slots.'
  llm_assisted: true