identifier: traitmech:000145
label: alpha-glucosidase activity
definition: A physiological enzyme-activity phenotype in which a cell produces active
  alpha-glucosidase enzymes that hydrolyze alpha-glucosidic bonds in alpha-D-glucosides.
definition_source: DOI:10.1371/journal.pone.0322500
trait_category: PHYSIOLOGY
term_kind: CLASS
mapping_status: PROPOSED
parent_traits:
- METPO:1000059
evidence:
- reference: DOI:10.1371/journal.pone.0322500
  snippet: Enzyme activities of acid- and alkaline-phosphatases, esterase, esterase
    lipase, leucine arylamidase, trypsin, naphthol-AS-BI phosphohydrolase, and alpha-glucosidase
    are present when assayed with API ZYM system.
  notes: Park et al. treated alpha-glucosidase as a positive API ZYM enzyme-activity
    phenotype in the Flexibacterium corallicola type species description.
- reference: DOI:10.3390/microorganisms13092005
  snippet: alkaline phosphatase, esterase (C4), lipoid esterase (C8), lipase (C14),
    leucine arylamines, valine arylamines, cystine arylaminase, pancreatic coagulase,
    acid phosphatase, naphthol-AS-BI-phosphohydrolase, alpha-glucosidase, and N-acetyl-glucosaminidase
    were positive
  notes: Zhang and Liu detected alpha-glucosidase in Microbulbifer weihaiensis SDUM041083T
    with the API ZYM enzyme activity panel.
canonical_examples:
- taxon_id: NCBITaxon:3037259
  taxon_label: Flexibacterium corallicola
  note: Park et al. reported Flexibacterium corallicola as positive for alpha-glucosidase
    in the API ZYM enzyme activity panel.
  reference: DOI:10.1371/journal.pone.0322500
discussions:
- discussion_id: alpha-glucosidase-activity-xref-gap
  prompt: Resolve an exact external ontology class for alpha-glucosidase activity
    before adding a TraitRecord xref.
  kind: CURATION_TODO
  status: OPEN
  rationale: GO:0090599 carries the same alpha-glucosidase activity label but denotes
    the enzyme molecular function rather than the organism-level alpha-glucosidase
    production phenotype, so it is appropriate as a causal-node grounding rather than
    an equivalent TraitRecord xref.
  posed_by: codex
  posed_date: '2026-09-11'
curation_history:
- timestamp: '2026-09-11T17:22:13Z'
  curator: codex
  action: MINTED_TRAITMECH_ID
  changes: Minted alpha-glucosidase activity as a DOI-backed TraitRecord after a repository-wide
    duplicate review covering ignored and hidden files; METPO has no exact alpha-glucosidase
    activity class yet.
  llm_assisted: true