>1|S81L|ARO:3003817|Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones|MEG_3183|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|Acinetobacter_baumannii|WP_000116450.1|81|gyrA_S81L|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_GyrA|wt_coherence=TRUE MSVSEIRPIAIEDELKHSYLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMHELGNDYNKAYKKSARVVGDVIGKYHPHGD LAVYETIVRMAQDFSLRYLLVDGQGNFGSIDGDSAAAMRYTEVRMTKLAHELLADLEKDTVDWEDNYDGSERIPEVLPTR VPNLLINGAAGIAVGMATNMAPHNMTEVVNACLAYADNPNISIEGLMEYITGPDFPTGGIIYGKSGIVDAYRTGKGRLHI RGKYHFEEDEKTGRTTIVFTEIPYQVNKARVIERIAELVKEKKLEGISELRDESDKEGMRIAIDLKRGENAEVVVNNLFL NTQLENSFSINMVCLDNGQPKLMNLKDIIAAFIRHRQEVVTRRTMFELRKARERGHILEGLTVALANIDEIIETIKTSAN PAEARERLLAGEWAGGGVVALLEKAGAISVRPDEIEGEDPNRPFGLSDSIYRLSPTQVGAILELRLHRLTGLEQDKLHAE YTEILGQIAELTAILNDFNLLMGVIREELAQVLQQYGDARRTEIVESRVDFCREDLIPEEQVVLTVSQTGYAKTQPLSDY QAQRRGGRGKSATSMKDDDFIQHLIVASNHATVLCFTNVGKVYRLKVFEVPQASRGAKGRPIVNLLPLDATETVTAILPL TEFPENHYVFMATASGTVKRVELEQFANIRSNGLRAIELNEEDTLIGVAITDGNQQIMLFSNEGKAIRFAETDVRAMGRT AKGVRGMRVSFASSTLSEEDADVENDDSDDNDDSTDSSLVSRIVSLVVVPETGEVLCASANGYGKRTPVNDFPTKKRGGK GVIAIKTSERNGELVGAVSIDETKELLLISDGGTLVRTRAAEVAMTGRNAQGVRLIRLSEEETLVGVVSIEAVEDEEELL EGEVDTTETDSEEAVSNNEDTSEE >2|G79C|ARO:3003817|Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones|MEG_3183|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|Acinetobacter_baumannii|WP_000116450.1|79|gyrA_G79C|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_GyrA|wt_coherence=TRUE MSVSEIRPIAIEDELKHSYLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMHELGNDYNKAYKKSARVVGDVIGKYHPHCD SAVYETIVRMAQDFSLRYLLVDGQGNFGSIDGDSAAAMRYTEVRMTKLAHELLADLEKDTVDWEDNYDGSERIPEVLPTR VPNLLINGAAGIAVGMATNMAPHNMTEVVNACLAYADNPNISIEGLMEYITGPDFPTGGIIYGKSGIVDAYRTGKGRLHI RGKYHFEEDEKTGRTTIVFTEIPYQVNKARVIERIAELVKEKKLEGISELRDESDKEGMRIAIDLKRGENAEVVVNNLFL NTQLENSFSINMVCLDNGQPKLMNLKDIIAAFIRHRQEVVTRRTMFELRKARERGHILEGLTVALANIDEIIETIKTSAN PAEARERLLAGEWAGGGVVALLEKAGAISVRPDEIEGEDPNRPFGLSDSIYRLSPTQVGAILELRLHRLTGLEQDKLHAE YTEILGQIAELTAILNDFNLLMGVIREELAQVLQQYGDARRTEIVESRVDFCREDLIPEEQVVLTVSQTGYAKTQPLSDY QAQRRGGRGKSATSMKDDDFIQHLIVASNHATVLCFTNVGKVYRLKVFEVPQASRGAKGRPIVNLLPLDATETVTAILPL TEFPENHYVFMATASGTVKRVELEQFANIRSNGLRAIELNEEDTLIGVAITDGNQQIMLFSNEGKAIRFAETDVRAMGRT AKGVRGMRVSFASSTLSEEDADVENDDSDDNDDSTDSSLVSRIVSLVVVPETGEVLCASANGYGKRTPVNDFPTKKRGGK GVIAIKTSERNGELVGAVSIDETKELLLISDGGTLVRTRAAEVAMTGRNAQGVRLIRLSEEETLVGVVSIEAVEDEEELL EGEVDTTETDSEEAVSNNEDTSEE >3|D105E|ARO:3003818|Acinetobacter baumannii parC conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDSACYEAMVLMAQPFSYRYPLVEGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >4|S84L|ARO:3003818|Acinetobacter baumannii parC conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_000202259.1|84|parC_S84L|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_ParC|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDLACYEAMVLMAQPFSYRYPLDVGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >5|V104I|ARO:3003818|Acinetobacter baumannii parC conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDSACYEAMVLMAQPFSYRYPLIDGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >6|Y151V|ARO:3004049|Escherichia coli fabG mutations conferring resistance to triclosan|MEG_2873|Biocides|Phenolic_compound_resistance|Triclosan-resistant_mutation|FABG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEV DILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANVAAAKAGLIG FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGG MYMV >7|G93A|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|93|fabI_G93A|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIAFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >8|G93S|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|93|fabI_G93S|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSISFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >9|G93V|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|93|fabI_G93V|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIVFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >10|M159T|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVTG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >11|F203L|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|203|fabI_F203L|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDLRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >12|F203C|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|203|fabI_F203C|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDCRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >13|F203A|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|Escherichia|WP_000506490.1|203|fabI_F203A|ISONIAZID/TRICLOSAN|ISONIAZID/TRICLOSAN|Escherichia_isoniazid/triclosan_resistant_FabI|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDARKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >14|F203V|ARO:3004045|Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDVRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI SGEVVHVDGGFSIAAMNELELK >15|V29G|ARO:3004145|AxyZ|MEG_1187|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_RND_efflux_pumps|AXYZ|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARKTKEESQRTRDRILDAAEHVFLSKGGASTTMSDIADFAGVSRGAVYGHYKNKIDVCIAMCDRALGEAVSLTRVSTDG EALEALYASMRQYVQIYAEEGSVQRVLEILYLKCERSDENAPLLRRRDLWERHALRTSEKLLRAAVSREDLPPALDVRLS NVYLHSLVEGVFGTICWSDRLKGDIWPRVERMLRAAIDTLRLSPQLRLPQAA >16|A64V|ARO:3003788|Bacillus subtilis pgsA with mutation conferring resistance to daptomycin|MEG_5779|Drugs|Lipopeptides|Daptomycin-resistant_mutant|PGSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKELSFHEKLLKLTKQQKKKTNKHVFIAIPIVFVLMFAFMWAGKAETPKVKTYSDDVLSASFVGDIMMGRYVEKVTEQK GADSIFQYVEPIFRASDYVAGNFENPVTYQKNYKQADKEIHLQTNKESVKVLKDMNFTVLNSANNHAMDYGVQGMKDTLG EFAKQNLDIVGAGYSLSDAKKKISYQKVNGVTIATLGFTDVSGKGFAAKKNTPGVLPADPEIFIPMISEAKKHADIVVVQ SHWGQEYDNDPNDRQRQLARAMSDAGADIIVGHHPHVLEPIEVYNGTVIFYSLGNFVFDQGWTRTRDSALVQYHLKKNGT GRFEVTPIDIHEATPAPVKKDSLKQKTIIRELTKDSNFAWKVEDGKLTFDIDHSDKLKSK >17|D90G|ARO:3003297|Bartonella bacilliformis gyrA conferring resistance to fluoroquinolones|MEG_3179|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDLTRLPEHDVSTGIEPVSIIEEMQCSYLDYAMSVIVSRALPDVRDGLKPVHRRILHAMNEMGLLFNKPYRKSAGVVGE VMGKFHPHGGASIYDALVRMAQDFSLRNPLIDGQGNFGSVDGDPPAAMRYTECRLEKVAEELLADIDKDTVDFQDNYDGR EHEPIVLPARFPNLLVNGSGGIAVGMATNIPPHNLGEVIDGCVALIDNPNITIDEMLAIIPGPDFPTGGIILGHSGVRSA YETGRGSIIMRAKVEIEEIRNQRQAIIVSEIPYQVNKATMVEKMAELVRDKRIEGISDLRDESDRDGYRVVIELKREAVA DVVLNQLYRYTPLQASFGCNMVALNGGKPEQMTLLDMLRAFVSFREEVVSRRTKYLLRKARERAHVLVGLAIAVANIDEI IELIRKAHDPQTARTQLMERRWPASEVAALIKLIDDPRHIIHEDNTYNLSEEQARAILELRLQRLTALGRNEIADELNAI GEDIADYLGILASRSRIMDIVKSELSALRETFATPRRTVFGFGSAEMDCEDLIVPEDMVVTVSHSGYIKRVPLNTYRAQR RGGKGRSGMATKDQDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPVGTPQSRGRALINMLPLQQGERITTIMPLPEDE ASWGKLDIMFATTRGTVRRNKLSDFIQVNRNGKIAMKLDEEGDEILSVETCTEHDDVVLITANGQCIRFPVTDIRVFSGR NSMGVRGINMVEGDKVISMTILEHVEATSVERSAYIKRAINERRVAGSDDEDILTVDEDGEETEVELTDERYAELSAHEQ MLLTVSEFGYGKRSSSYDFRISGRGGKGIRATDLSKAAEIGKLVAAFPVGERDQIMLVSDGGQLIRVPVNCIRIAGRSTK GVTVFNTAKGEKVVSVERISESENDTNQLDIESEEHSGTVSMSEEKKL >18|D95N|ARO:3003297|Bartonella bacilliformis gyrA conferring resistance to fluoroquinolones|MEG_3179|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDLTRLPEHDVSTGIEPVSIIEEMQCSYLDYAMSVIVSRALPDVRDGLKPVHRRILHAMNEMGLLFNKPYRKSAGVVGE VMGKFHPHGDASIYNALVRMAQDFSLRNPLIDGQGNFGSVDGDPPAAMRYTECRLEKVAEELLADIDKDTVDFQDNYDGR EHEPIVLPARFPNLLVNGSGGIAVGMATNIPPHNLGEVIDGCVALIDNPNITIDEMLAIIPGPDFPTGGIILGHSGVRSA YETGRGSIIMRAKVEIEEIRNQRQAIIVSEIPYQVNKATMVEKMAELVRDKRIEGISDLRDESDRDGYRVVIELKREAVA DVVLNQLYRYTPLQASFGCNMVALNGGKPEQMTLLDMLRAFVSFREEVVSRRTKYLLRKARERAHVLVGLAIAVANIDEI IELIRKAHDPQTARTQLMERRWPASEVAALIKLIDDPRHIIHEDNTYNLSEEQARAILELRLQRLTALGRNEIADELNAI GEDIADYLGILASRSRIMDIVKSELSALRETFATPRRTVFGFGSAEMDCEDLIVPEDMVVTVSHSGYIKRVPLNTYRAQR RGGKGRSGMATKDQDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPVGTPQSRGRALINMLPLQQGERITTIMPLPEDE ASWGKLDIMFATTRGTVRRNKLSDFIQVNRNGKIAMKLDEEGDEILSVETCTEHDDVVLITANGQCIRFPVTDIRVFSGR NSMGVRGINMVEGDKVISMTILEHVEATSVERSAYIKRAINERRVAGSDDEDILTVDEDGEETEVELTDERYAELSAHEQ MLLTVSEFGYGKRSSSYDFRISGRGGKGIRATDLSKAAEIGKLVAAFPVGERDQIMLVSDGGQLIRVPVNCIRIAGRSTK GVTVFNTAKGEKVVSVERISESENDTNQLDIESEEHSGTVSMSEEKKL >19|T214I|ARO:3003302|Bartonella bacilliformis gyrB conferring resistance to aminocoumarin|MEG_3246|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDETTSPTSGDYGAASIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGYATLVNVTLHADGSCSVC DNGRGIPTDIHPTEHVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVWLRLRIKRDGKIHEMSFTHGVADA PLKVVGQCGTESGTEISFLPSPETFTMVKFDFETLERRLRELAFLNSGVHILLINQHHADVRSVELYYEGGLIEFIKYID QSKKPLIDAPIYITSEKDGISVDVALWWNDSYHEKVLCFTNNIPQRDGGTHLAGFRSALTRQINGYAESSGIAKKEKVNL TGDDCREGLTAILSVKVPDPKFSSQTKDKLVSSEVRPIVENLVNEGLSAWLEEHPNEAKILISKVVEAAAAREAARKARE LTRRKGALDITSLPGKLADCQERDPTKSEIFIVEGDSAGGSAKSGRSRQNQAILPLRGKILNVERARFDRMLSSEMIGTL ITALGTSIGKDEFSPDKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPELIERGHLYIAQPPLYKVSRGKSSQYIKNEA AFEDFLIDSGLEETTLELSSGEVCAGIDLRQFVQDARLLRQLLNGLHTRYDRNIVEQAAIAGAFNFEAFATPETAQKIAD TIAKRLDLIADDMERGWSGQYTSDGSLCFERVLRGVKDVITLDAGFINSADARQIGHIAKNLKDIYRDPPLLRRKDKSER IFGPTSLLESIFINGKKGITLQRYKGLGEMNADQLWETTLDPDARSLLQVKINDATDADSLFSQLMGDEVEPRRIFIQKN ALNVANLDI >20|T214A|ARO:3003302|Bartonella bacilliformis gyrB conferring resistance to aminocoumarin|MEG_3246|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDETTSPTSGDYGAASIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGYATLVNVTLHADGSCSVC DNGRGIPTDIHPTEHVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVWLRLRIKRDGKIHEMSFTHGVADA PLKVVGQCGTESGTEISFLPSPETFTMVKFDFETLERRLRELAFLNSGVHILLANQHHADVRSVELYYEGGLIEFIKYID QSKKPLIDAPIYITSEKDGISVDVALWWNDSYHEKVLCFTNNIPQRDGGTHLAGFRSALTRQINGYAESSGIAKKEKVNL TGDDCREGLTAILSVKVPDPKFSSQTKDKLVSSEVRPIVENLVNEGLSAWLEEHPNEAKILISKVVEAAAAREAARKARE LTRRKGALDITSLPGKLADCQERDPTKSEIFIVEGDSAGGSAKSGRSRQNQAILPLRGKILNVERARFDRMLSSEMIGTL ITALGTSIGKDEFSPDKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPELIERGHLYIAQPPLYKVSRGKSSQYIKNEA AFEDFLIDSGLEETTLELSSGEVCAGIDLRQFVQDARLLRQLLNGLHTRYDRNIVEQAAIAGAFNFEAFATPETAQKIAD TIAKRLDLIADDMERGWSGQYTSDGSLCFERVLRGVKDVITLDAGFINSADARQIGHIAKNLKDIYRDPPLLRRKDKSER IFGPTSLLESIFINGKKGITLQRYKGLGEMNADQLWETTLDPDARSLLQVKINDATDADSLFSQLMGDEVEPRRIFIQKN ALNVANLDI >21|R184Q|ARO:3003302|Bartonella bacilliformis gyrB conferring resistance to aminocoumarin|MEG_3246|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDETTSPTSGDYGAASIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGYATLVNVTLHADGSCSVC DNGRGIPTDIHPTEHVSAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSVWLRLRIKRDGKIHEMSFTHGVADA PLKVVGQCGTESGTEISFLPSPEQFTMVKFDFETLERRLRELAFLNSGVHILLVNQHHADVRSVELYYEGGLIEFIKYID QSKKPLIDAPIYITSEKDGISVDVALWWNDSYHEKVLCFTNNIPQRDGGTHLAGFRSALTRQINGYAESSGIAKKEKVNL TGDDCREGLTAILSVKVPDPKFSSQTKDKLVSSEVRPIVENLVNEGLSAWLEEHPNEAKILISKVVEAAAAREAARKARE LTRRKGALDITSLPGKLADCQERDPTKSEIFIVEGDSAGGSAKSGRSRQNQAILPLRGKILNVERARFDRMLSSEMIGTL ITALGTSIGKDEFSPDKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPELIERGHLYIAQPPLYKVSRGKSSQYIKNEA AFEDFLIDSGLEETTLELSSGEVCAGIDLRQFVQDARLLRQLLNGLHTRYDRNIVEQAAIAGAFNFEAFATPETAQKIAD TIAKRLDLIADDMERGWSGQYTSDGSLCFERVLRGVKDVITLDAGFINSADARQIGHIAKNLKDIYRDPPLLRRKDKSER IFGPTSLLESIFINGKKGITLQRYKGLGEMNADQLWETTLDPDARSLLQVKINDATDADSLFSQLMGDEVEPRRIFIQKN ALNVANLDI >22|G125S|ARO:3003302|Bartonella bacilliformis gyrB conferring resistance to aminocoumarin|MEG_3246|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDETTSPTSGDYGAASIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVYEVVDNAIDEALAGYATLVNVTLHADGSCSVC DNGRGIPTDIHPTEHVSAAEVIMTQLHAGGKFDQNSYKVSGGLHSVGVSVVNALSVWLRLRIKRDGKIHEMSFTHGVADA PLKVVGQCGTESGTEISFLPSPETFTMVKFDFETLERRLRELAFLNSGVHILLVNQHHADVRSVELYYEGGLIEFIKYID QSKKPLIDAPIYITSEKDGISVDVALWWNDSYHEKVLCFTNNIPQRDGGTHLAGFRSALTRQINGYAESSGIAKKEKVNL TGDDCREGLTAILSVKVPDPKFSSQTKDKLVSSEVRPIVENLVNEGLSAWLEEHPNEAKILISKVVEAAAAREAARKARE LTRRKGALDITSLPGKLADCQERDPTKSEIFIVEGDSAGGSAKSGRSRQNQAILPLRGKILNVERARFDRMLSSEMIGTL ITALGTSIGKDEFSPDKLRYHKIIIMTDADVDGAHIRTLLLTFFFRQMPELIERGHLYIAQPPLYKVSRGKSSQYIKNEA AFEDFLIDSGLEETTLELSSGEVCAGIDLRQFVQDARLLRQLLNGLHTRYDRNIVEQAAIAGAFNFEAFATPETAQKIAD TIAKRLDLIADDMERGWSGQYTSDGSLCFERVLRGVKDVITLDAGFINSADARQIGHIAKNLKDIYRDPPLLRRKDKSER IFGPTSLLESIFINGKKGITLQRYKGLGEMNADQLWETTLDPDARSLLQVKINDATDADSLFSQLMGDEVEPRRIFIQKN ALNVANLDI >23|L71R|ARO:3003582|basR|MEG_1197|Drugs|Cationic_antimicrobial_peptides|Polymyxin_B_resistance_regulator|BASRS|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRILLAEDDLLLGDGIRAGLRLEGDTVEWVTDGVAAENALVTDEFDLLVLDIGLPRRSGLDILRNLRHQGRLTPVLLLTA RDKVADRVAGLDSGADDYLTKPFDLDELQARVRALTRRTTGRALPQLVHGELRLDPATHQVTLSGQAVELAPREYALLRL LLENSGKVLSRNQLEQSLYGWSGDVESNAIEVHVHHLRRKLGNQLIRTVRGIGYGIDQPAP >24|L157Q|ARO:3003582|basR|MEG_1197|Drugs|Cationic_antimicrobial_peptides|Polymyxin_B_resistance_regulator|BASRS|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRILLAEDDLLLGDGIRAGLRLEGDTVEWVTDGVAAENALVTDEFDLLVLDIGLPRRSGLDILRNLRHQGLLTPVLLLTA RDKVADRVAGLDSGADDYLTKPFDLDELQARVRALTRRTTGRALPQLVHGELRLDPATHQVTLSGQAVELAPREYAQLRL LLENSGKVLSRNQLEQSLYGWSGDVESNAIEVHVHHLRRKLGNQLIRTVRGIGYGIDQPAP >25|D116C|ARO:3003777|Borreliella burgdorferi murA with mutation conferring resistance to fosfomycin|MEG_4092|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIPNINDVKVVLDILNDIGADIAREGNTLKIKVLNIVK TEIDSSFTDLIRASILLLGPFVSRFGKIDMALPGGCVIGKRRLDTHFYGLCKLGAKLSTKDRRIVLKANKLVGAEMFLDE ASVTATENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTVFRIGADFMQVGSLIS LAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNKQELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIVVT ATQVEGTVLVFEKMFESRMFFVDKLIKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNV YQIERGYEDVVNKLINLGAKIKKVKSQ >26|T83I|ARO:3004860|Burkholderia dolosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH GDIAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNETQPSVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLSNPDATVDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRAATHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMTKSWDSSLVREMLTRAESENAAAGGRAAYRPEGLNPAYGMQADGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTTVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYMLCFSNRGRVYWIKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSERNGKVVAATLVD PEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQIAEAEEGDGEADEASDGEA >27|D87H|ARO:3004860|Burkholderia dolosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH GDTAVYHTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNETQPSVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLSNPDATVDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRAATHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMTKSWDSSLVREMLTRAESENAAAGGRAAYRPEGLNPAYGMQADGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTTVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYMLCFSNRGRVYWIKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSERNGKVVAATLVD PEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQIAEAEEGDGEADEASDGEA >28|G81D|ARO:3004860|Burkholderia dolosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH DDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNETQPSVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLSNPDATVDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRAATHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMTKSWDSSLVREMLTRAESENAAAGGRAAYRPEGLNPAYGMQADGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTTVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYMLCFSNRGRVYWIKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSERNGKVVAATLVD PEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQIAEAEEGDGEADEASDGEA >29|T86I|ARO:3003789|Campylobacter jejuni gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|86|gyrA_T86I|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDIAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >30|G80N|ARO:3003931|Capnocytophaga gingivalis gyrA conferring resistance to fluoroquinolones|MEG_3176|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVEGEKLIPINIEDQMKTAYIDYSMSVIVSRALPDVRDGLKPVHRRVLFGMHELGVRSNTAHKKSARIVGEVLGKYHPHN DSSVYDTMVRMAQWWNMRYMLVDGQGNFGSIDGDSPAAMRYTEARMRKMAEDMLIDIDKETVDHSLNFDDTLLEPTVLPT RIPNLLVNGSSGIAVGMATNMPPHNLAEVVDGIIAYLGNQDITIDELMEYIKAPDFPTGGIIYGYDGVREAFKTGRGRVV IRAKAHFEEVNGRDCIVVTEVPYQVNPETMREQTSNLVKEGKLEGLADIVDQTGKGGMRIVYELKKDAIPNVVLNNLFKH TALQSSFSVNNIALVNGRPQQLNLKDLIYHFVEHRHDVVYRRTEYELKKAKERIHILEGFMKVMATEDTMGKAIEIIRFH DKPKEDLMTEFELTEIQAEAILALQLRRINKLLILQTKEEYEQLLAQIIDLEDILARKERRTEIIKEELLEIKSKYGDER RSVIEYAGGDISIEDIIPDDQVVITISNAGYIKRTSVNEYKTQARGGVGQKASATRDKDFIEHLFIGTNHQYMLFFTEKG KCFWLRVYEIPEGGKNTKGRAIQNLINIEPDDLVKAVICTHDLKEKDYTNSHYVIMATKKGIIKKTSLEQYSRPRQNGIV AITIKEDDELLEARLTSGNSQIMLAVKSGKAIRFPEDKVRAVGRSGSGVRGISLDSDKDEVIGMIAIENPLEETVLVVSE NGYGKRTFIDEPETGEAVYRITNRGGKGVKTISITEKTGNLVAIKSVLEEDDLMIINKSGMAIRLPVSGLRVMGRATQGV RLINIKGNDSIAAVAKVMKEDEDENTTEEIENPTEE >31|G261E|ARO:3003357|Clostridioides difficile EF-Tu mutants conferring resistance to elfamycin|MEG_7304|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGEAVDFANIDKAPEERERGITISTAHVEYETPNRHYAH VDCPGHADYVKNMITGAAQMDGAILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLK VQDEVELVGLTEAPRKVVVTEVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEG GRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE >32|T82I|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DIAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >33|A384D|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIDLDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >34|C245T|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRTFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >35|D71V|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGVVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >36|T82V|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DVAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >37|A118T|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPATMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >38|D71G|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGGVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >39|T82A|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DAAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >40|D81N|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG NTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >41|R90K|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVKMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >42|D103N|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVNGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >43|Q123K|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTKAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >44|P116A|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSAAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >45|A92E|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMEQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >46|A118S|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPASMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >47|L345I|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DTAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNIKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >48|D409N|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKNADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >49|R457T|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVETQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >50|D465Y|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILYYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >51|R447L|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILLLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >52|E467V|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYVEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >53|S416A|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKAPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >54|D426V|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVVGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >55|R447K|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILKLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >56|E467K|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYKEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >57|S366V|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQEVPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >58|K444F|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQFILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >59|S464T|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKITGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >60|I139R|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >61|V130I|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALIEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >62|V423F|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIFLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >63|D426N|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVNGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >64|S366A|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQEAPQVAKMILDKSLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >65|R377G|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKGLMASRAREAARKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >66|R388P|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAAPKARELTRRKSIL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >67|E399K|ARO:3004562|Clostridioides difficile gyrB conferring resistance to fluoroquinolones|MEG_3241|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMQEKKQTYDENQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVYEIVDNSIDEALAGYCDKINVIIHKDNSITVTDNGRG MPVGMHHKMKKPTVEVIMTILHAGGKFGGGGYKVSGGLHGVGASVVNALSEICEVEVKRESHIWRQVFKRGKVASGLDII GDSEEHGTKIHFKPDAEIFDEIEYDYDTLAQRLRELAFLNKGIKIRLEDERDDKEEIFHYEGGIKSFVTYLNRNKQPIHK EPIYVEGKKDDYSVEIAIQYNDGYTENIFAFANNIDTVEGGTHLAGFKSALTRVFNDYAKKFGILKENDKNLSGEDIREG LTAVISVKLVDPQFEGQTKTKLGNSEVRGIVDSIMGESLNNFLQENPQVAKMILDKSLMASRAREAARKARELTRRKSKL ENTSLPGKLADCSSKDPSECEIYLVEGDSAGGSAKQGRNRKFQAILPLRGKIMNVEKQRLDKILGYEEIRAMITAFGAGI GKDFDVNKIRYNKIIIMTDADVDGAHIRTLLLTFFFRYMKELVEKCHVYIAQPPLYRVAKGKKEYYAYSDDELDVLLTEI GGKDSNVDIQRYKGLGEMDSEQLWDTTMNPETRTLIQVNVEDTMAADEIFTILMGDKVEPRRNFIQENAKKVVNLDI >68|P107L|ARO:3004561|Clostridioides difficile murG with mutation conferring resistance to vancomycin|MEG_4097|Drugs|Glycopeptides|Vancomycin-resistant_mutation|MURG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKLKIVMTGGGSAGHVTPNLALVPKLKELGYEIEYIGTKDGIERSIIEKENIKYNCISSGKLRRYIDIKNFSDPFKVIL GIFQSVSILRKKKPNIVFSKGGFVSVLVVIAAHFCRIPVIAHESDITPGLANRIAVPYCTKVCATFPESLNNIKGNKGIL TGTPIRDELFKGSKIKGLEICGFTGEKPVLMIIGGSLGSKIINDTVREALNKLIKKYDIVHICGKGNIDEALSKLKGYKQ FDYISTELPHVMNAADLVISRAGANAIFELLALKKPNLLIPLSKKSSRGDQILNAMSFEKNGYSMVVQEDDLTPTLLVEK VIKLESDKEKYKKAMNSSPVKNGVENIIKVIDKYKKCKI >69|D492N|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMNQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >70|H502Y|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTYKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >71|H502L|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTLKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >72|P496S|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNSLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >73|S498T|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLTELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >74|S488P|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLPQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >75|H502N|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTNKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >76|R505K|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTHKRKLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >77|S488T|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLTQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >78|S550Y|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINYLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >79|Q1074R|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTRQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >80|S550F|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINFLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >81|D492V|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMVQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >82|D245Y|ARO:3004681|Clostridioides difficile rpoC with mutation conferring resistance to vancomycin|MEG_6138|Drugs|Glycopeptides|Vancomycin-resistant_mutation|RPOC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKDGLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGV EVTKSKVRRERMGHIELAAPMSHIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKKSGNKPEWMILDAIPVIPPDLRP MVQLYGGRFATSDLNDLYRRVINRNNRLKRLLELGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDML KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEKVKPEVWDV LEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADFDGDQMAVHVPLSVEAQAEARFLMLSVNNIL APKDGSPITTPSQDMVLGCYYLTIEAQDGAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFI FNENIPQDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYSTLGGITVAVDDMSVPEE KKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTDKVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMR GLMANASGKTVEIPVKSNFREGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEIYA IKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKIRIRTVLNCKTNHGVCSKCYGRNLA TGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKE VNVIPEEGETQTYVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQGVDVNDKHIEV IVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAKRVLLGITKASLATDSFLSAASFQETTRVLTEA AIKGKEDHLIGLKENVILGKLIPAGTGMKKYRNIAVEKIED >83|D105G|ARO:3003974|Cutibacterium acnes gyrA conferring resistance to fluoroquinolones|MEG_3182|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADDEKPDEQNQADRQGLVTGRHVGIQPVEIRDEIQNAYLDYAMSVIVGRALPDVRDGLKPVHRRVIYAMYDGGYRPDRG WNKCSRVVGDVMGKYHPHGDSAIYGTLVRLAQPWAMRYKLVQGQGNFGSQGNDGAAAMRYTECKMAPLAMEMVRDIDQDT VDFQPNYDNKETEPVVLPSRFPNLLVNGSSGIAVGMATNIPTHNLREVNEAVQWSLAHPNASHEELLEACMERIKGPDFP GGALIVGRQGIEDAYRTGRGSVTMRAVIDMEEDKKGRQCLVVTELPYMCNPDNLATKIADLVNSGRINGIADIRDDSSAR TGQRLVIVLKRDAQPRVVMNNLYKHTALQDTFGCNMLALVDNVPRTLRLDQFISYWIDHQMEVIRRRTEYRLAQAEKDAH IQRALVKALDMLDEVIALIRRSPNTEAASTGLQELLDIDEIQARAILDMQLRRLAALERQKIIDRLEELERLIADYKAIL ASEDRQREIISTELAEIVDKYGDERRTRIIAADGDFSEEDFIPDDDVVVTITRGGYAKRTRTDLYRVQKRGGKGVRGASL RTDDEVAQLFTTTNHQWILFFTNMGRVYRTKVWQLPEAGRDARGGHVAGLLSFLPDEKIAQVMTLRSYDDAEYLLLATRK GMVKKTALKAYDSSRQAGVIAVNFRTEDDELIGAEQCSAADDVLLISRKGQAIRFSAGDDQLRPMGRATSGVTGMKFRGD DELLSMSIIHSDMPEDDRFVFTATGGGYAKRTAVSEYRQQRRGGVGIKAMALSEERGSLVGGLVVSEADEIIAIKTSGQI TRSAVSEVPAKGRSTMGVKFVSVRGDDAVSIIAVNPEHTVEEEVADESVETVEGDATKAQSGDVVRRSDTVDDDRAVDTA GNDMKPEDNGE >84|S101L|ARO:3003974|Cutibacterium acnes gyrA conferring resistance to fluoroquinolones|MEG_3182|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADDEKPDEQNQADRQGLVTGRHVGIQPVEIRDEIQNAYLDYAMSVIVGRALPDVRDGLKPVHRRVIYAMYDGGYRPDRG WNKCSRVVGDVMGKYHPHGDLAIYDTLVRLAQPWAMRYKLVQGQGNFGSQGNDGAAAMRYTECKMAPLAMEMVRDIDQDT VDFQPNYDNKETEPVVLPSRFPNLLVNGSSGIAVGMATNIPTHNLREVNEAVQWSLAHPNASHEELLEACMERIKGPDFP GGALIVGRQGIEDAYRTGRGSVTMRAVIDMEEDKKGRQCLVVTELPYMCNPDNLATKIADLVNSGRINGIADIRDDSSAR TGQRLVIVLKRDAQPRVVMNNLYKHTALQDTFGCNMLALVDNVPRTLRLDQFISYWIDHQMEVIRRRTEYRLAQAEKDAH IQRALVKALDMLDEVIALIRRSPNTEAASTGLQELLDIDEIQARAILDMQLRRLAALERQKIIDRLEELERLIADYKAIL ASEDRQREIISTELAEIVDKYGDERRTRIIAADGDFSEEDFIPDDDVVVTITRGGYAKRTRTDLYRVQKRGGKGVRGASL RTDDEVAQLFTTTNHQWILFFTNMGRVYRTKVWQLPEAGRDARGGHVAGLLSFLPDEKIAQVMTLRSYDDAEYLLLATRK GMVKKTALKAYDSSRQAGVIAVNFRTEDDELIGAEQCSAADDVLLISRKGQAIRFSAGDDQLRPMGRATSGVTGMKFRGD DELLSMSIIHSDMPEDDRFVFTATGGGYAKRTAVSEYRQQRRGGVGIKAMALSEERGSLVGGLVVSEADEIIAIKTSGQI TRSAVSEVPAKGRSTMGVKFVSVRGDDAVSIIAVNPEHTVEEEVADESVETVEGDATKAQSGDVVRRSDTVDDDRAVDTA GNDMKPEDNGE >85|V241D|ARO:3003970|D-Ala-D-Ala ligase|MEG_7333|Drugs|Glycopeptides|VanA-type_resistance_protein|VAN|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKIILLYGGRSAEHDVSLLSAFSVVNAVYYNYYQVQLVMITRDGQWLKGSLLTEAPTSKEVLNLTDSAYQGTPIQPGEIK EEDAIVFPLLHGPNGEDGTIQGFLETIGMPYVGAGVLTSACGMDKIMTKYILQAAGIPQVPYVPVLKNYWKENPKKVFEQ CEGSLLYPMFIKPANMGSSVGITKAENREELQNALQEAYRYDTRAIVEQGIEAREIEVAVLGNEDVRTTMPGEIVKDVAF DDYNSKYLDNKIEMQIPAQIPEETQAKAQEFAKKAYTMLGGSGLSRCDFFLTNKNELFLNELNTMPGFTEFSMYPLLWEK TGLPYGDLIEELIQLGVNRFKQRQAFLTDVE >86|D295G|ARO:3003970|D-Ala-D-Ala ligase|MEG_7333|Drugs|Glycopeptides|VanA-type_resistance_protein|VAN|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKIILLYGGRSAEHDVSLLSAFSVVNAVYYNYYQVQLVMITRDGQWLKGSLLTEAPTSKEVLNLTDSAYQGTPIQPGEIK EEDAIVFPLLHGPNGEDGTIQGFLETIGMPYVGAGVLTSACGMDKIMTKYILQAAGIPQVPYVPVLKNYWKENPKKVFEQ CEGSLLYPMFIKPANMGSSVGITKAENREELQNALQEAYRYDTRAIVEQGIEAREIEVAVLGNEDVRTTMPGEIVKDVAF YDYNSKYLDNKIEMQIPAQIPEETQAKAQEFAKKAYTMLGGSGLSRCDFFLTNKGELFLNELNTMPGFTEFSMYPLLWEK TGLPYGDLIEELIQLGVNRFKQRQAFLTDVE >87|P313L|ARO:3003970|D-Ala-D-Ala ligase|MEG_7333|Drugs|Glycopeptides|VanA-type_resistance_protein|VAN|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKIILLYGGRSAEHDVSLLSAFSVVNAVYYNYYQVQLVMITRDGQWLKGSLLTEAPTSKEVLNLTDSAYQGTPIQPGEIK EEDAIVFPLLHGPNGEDGTIQGFLETIGMPYVGAGVLTSACGMDKIMTKYILQAAGIPQVPYVPVLKNYWKENPKKVFEQ CEGSLLYPMFIKPANMGSSVGITKAENREELQNALQEAYRYDTRAIVEQGIEAREIEVAVLGNEDVRTTMPGEIVKDVAF YDYNSKYLDNKIEMQIPAQIPEETQAKAQEFAKKAYTMLGGSGLSRCDFFLTNKNELFLNELNTMPGFTEFSLYPLLWEK TGLPYGDLIEELIQLGVNRFKQRQAFLTDVE >88|E13G|ARO:3003970|D-Ala-D-Ala ligase|MEG_7333|Drugs|Glycopeptides|VanA-type_resistance_protein|VAN|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKIILLYGGRSAGHDVSLLSAFSVVNAVYYNYYQVQLVMITRDGQWLKGSLLTEAPTSKEVLNLTDSAYQGTPIQPGEIK EEDAIVFPLLHGPNGEDGTIQGFLETIGMPYVGAGVLTSACGMDKIMTKYILQAAGIPQVPYVPVLKNYWKENPKKVFEQ CEGSLLYPMFIKPANMGSSVGITKAENREELQNALQEAYRYDTRAIVEQGIEAREIEVAVLGNEDVRTTMPGEIVKDVAF YDYNSKYLDNKIEMQIPAQIPEETQAKAQEFAKKAYTMLGGSGLSRCDFFLTNKNELFLNELNTMPGFTEFSMYPLLWEK TGLPYGDLIEELIQLGVNRFKQRQAFLTDVE >89|G98R|ARO:3003970|D-Ala-D-Ala ligase|MEG_7333|Drugs|Glycopeptides|VanA-type_resistance_protein|VAN|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKIILLYGGRSAEHDVSLLSAFSVVNAVYYNYYQVQLVMITRDGQWLKGSLLTEAPTSKEVLNLTDSAYQGTPIQPGEIK EEDAIVFPLLHGPNGEDRTIQGFLETIGMPYVGAGVLTSACGMDKIMTKYILQAAGIPQVPYVPVLKNYWKENPKKVFEQ CEGSLLYPMFIKPANMGSSVGITKAENREELQNALQEAYRYDTRAIVEQGIEAREIEVAVLGNEDVRTTMPGEIVKDVAF YDYNSKYLDNKIEMQIPAQIPEETQAKAQEFAKKAYTMLGGSGLSRCDFFLTNKNELFLNELNTMPGFTEFSMYPLLWEK TGLPYGDLIEELIQLGVNRFKQRQAFLTDVE >90|T450I|ARO:3003761|eatAv|MEG_2694|Drugs|Multi-drug_resistance|Multi-drug_ABC_efflux_pumps|EATAV|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGKTTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERL TYYVLNDITDFEIWEIERELQLMQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEKLKKEVSRLKKTAAEKAEWSRSR EGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSKAIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDL QLGYENLLFEPIHFTIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGTLAEFAEKN QVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYIWDEPLNYLDVFNQEQLEQLILNVKPAMLLV EHDQTFLDKVSTEIISLERI >91|H215R|ARO:3003760|Enterococcus faecalis cls with mutation conferring resistance to daptomycin|MEG_1731|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002413481.1|215|cls_H215R|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_Cls|wt_coherence=TRUE MILSVLTVIYFINAIIAGITILLKPRDVAAIWAWLLVLIALPVFGFFLYLFFGRGLTDKKKFYLQQSDLRELENFQNFQE ESFELYSQKMPTEEQQQFTDFFSSLNRMPLTKKNDVEIFTDGTEKFNALMADIKKAQHSIHIEYYAFVTDHIGTKILNLL EEKAAEGVEVRLLYDAFGSKGTKVHHLNELKKNGGFVQTFITSQKALLKFRLNYRDHRKIVVIDGKVGYIGGFNVADQYA GTTKKFGYWRDTHLRIQGPATSLLQMRFLMDWNVSSPEKNRVAYQLDYFFKLEALVPEANTSIQMIASGPNSDREQIKLA FIKLITSAKKRVWIQTPYLVPDDSVLAALKVAAASGVDVKIMIPDKPDHPFIYRATQYYGRLLMKENIEILIYNGGFLHA KTMIMDDEVCTVGSANQDIRSYKLNFEANAVLYDKKIIDQLEAIFLEDRKKCTTMTPEVVRDMSKWLIFKQQISRLFSPI L >92|R267H|ARO:3003760|Enterococcus faecalis cls with mutation conferring resistance to daptomycin|MEG_1731|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002413481.1|267|cls_R267H|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_Cls|wt_coherence=TRUE MILSVLTVIYFINAIIAGITILLKPRDVAAIWAWLLVLIALPVFGFFLYLFFGRGLTDKKKFYLQQSDLRELENFQNFQE ESFELYSQKMPTEEQQQFTDFFSSLNRMPLTKKNDVEIFTDGTEKFNALMADIKKAQHSIHIEYYAFVTDHIGTKILNLL EEKAAEGVEVRLLYDAFGSKGTKVHHLNELKKNGGFVQTFITSQKALLKFRLNYHDHRKIVVIDGKVGYIGGFNVADQYA GTTKKFGYWRDTHLRIQGPATSLLQMHFLMDWNVSSPEKNRVAYQLDYFFKLEALVPEANTSIQMIASGPNSDREQIKLA FIKLITSAKKRVWIQTPYLVPDDSVLAALKVAAASGVDVKIMIPDKPDHPFIYRATQYYGRLLMKENIEILIYNGGFLHA KTMIMDDEVCTVGSANQDIRSYKLNFEANAVLYDKKIIDQLEAIFLEDRKKCTTMTPEVVRDMSKWLIFKQQISRLFSPI L >93|R218Q|ARO:3003760|Enterococcus faecalis cls with mutation conferring resistance to daptomycin|MEG_1731|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002413481.1|218|cls_R218Q|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_Cls|wt_coherence=TRUE MILSVLTVIYFINAIIAGITILLKPRDVAAIWAWLLVLIALPVFGFFLYLFFGRGLTDKKKFYLQQSDLRELENFQNFQE ESFELYSQKMPTEEQQQFTDFFSSLNRMPLTKKNDVEIFTDGTEKFNALMADIKKAQHSIHIEYYAFVTDHIGTKILNLL EEKAAEGVEVRLLYDAFGSKGTKVHHLNELKKNGGFVQTFITSQKALLKFRLNYHDHQKIVVIDGKVGYIGGFNVADQYA GTTKKFGYWRDTHLRIQGPATSLLQMRFLMDWNVSSPEKNRVAYQLDYFFKLEALVPEANTSIQMIASGPNSDREQIKLA FIKLITSAKKRVWIQTPYLVPDDSVLAALKVAAASGVDVKIMIPDKPDHPFIYRATQYYGRLLMKENIEILIYNGGFLHA KTMIMDDEVCTVGSANQDIRSYKLNFEANAVLYDKKIIDQLEAIFLEDRKKCTTMTPEVVRDMSKWLIFKQQISRLFSPI L >94|E554K|ARO:3003805|Enterococcus faecalis gshF with mutation conferring daptomycin resistance|MEG_3175|Drugs|Lipopeptides|Daptomycin-resistant_mutant|GSHF|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002389492.1|554|gshF_E554K|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_GshF|wt_coherence=TRUE MNYRELMQKKNVRPYVLMARFGLEKENQRSTREGLLATTDHPTVFGNRSYHPYIQTDFSETQLELITPVANSGTEMLRFL DAIHDVARRSIPEDEMLWPLSMPPQLPTKDEEIKIAKLDQYDAVLYRRYLAKEYGKRKQMVSGIHFNFEYDQALIQQLYD EQSEVTDCKQFKTKVYMKVARNFLRYRWLITYLFGASPVSEDGYFRVYDDQPQEPIRSIRNSTYGYRNHDNVKVSYASLE RYLEDIHRMVENGLLSEEKEFYAPVRLRGGKQMSDLPKTGIRYIELRNLDLNPFSRLGIVEDTVDFLHYFMLYLLWTDEK EEADEWVKTGDILNEQVALGHPHETIKLIAEGDRIFSEMIDMLDALGIRKGKEVVGKYYQQLRNPQDTVSGKMWTIIQEN SNSELGNIFGNQYQSMAFERPYQLAGFREMELSTQIFLFDAIQKGLEIEILDEQEQFLKLQHGEHIEYVKNANMTSKDNY VVPLIMENKTVTKKILSAAGFHVPGGEEFSSFIEAQEAHLRYANKAFVVKPKSTNYGLGITIFKEGASLEDFTKALRIAF KEDTAVLIEEFLPGTEYRFFVLDNDVKAIMLRVPANVTGDGKHTVEELVAAKNSDPLRGTNHRAPLELIQLNDLEKLMLK EQGLTIYSVPEKEQIVYLRENSNVSTGGDSIDMTDVIDDSYKQIAIEAVAALGAKICGIDLIIPDKDVKGTRDSLTYGII EANFNPAMHMHVYPYAGQGRRLTMDVLKLLYPEVVQ >95|T194I|ARO:3003077|Enterococcus faecalis liaF mutant conferring daptomycin resistance|MEG_3588|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002381168.1|194|liaF_T194I|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_LiaF|wt_coherence=TRUE MNNPWRFFIVAEALLFILALWQIVHNPGLAVLLTIGVLLVAYVSRKASKTHFNNFQFVLGVVFIVIGAMNSTAVWFMLIF GVLFIGLKGFEISGVDIAERAPWRKKQMIMVETAAKEPKNGKRFKRRWFANERIGNNIYEWDDINIDLISGDTIIDLGNT LLPKEDNIIIIRKGFGRTRILVPLGVAILLEHSIFYGTVRFEEEKYQLKNESLKIYSNDYDTNLRRLKIMTNTLVGDVEV IRV >96|D192N|ARO:3003792|Enterococcus faecalis liaR mutant conferring daptomycin resistance|MEG_3586|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MIKVMLVDDHEMVRLGVSSYLSIQEDIEVVGEAENGKIGYEKALELRPDVILMDLVMEEMDGIDSTKAILKDWPEAKIII VTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATYRGERVLEPEVTHKMMERLTKKQEPVLHEDLTNREHEILMLI AQGKSNQEIADELFITLKTVKTHVSNILAKLNVDDRTQAAIYAFQHGLAK >97|A180T|ARO:3003791|Enterococcus faecalis liaS mutant conferring daptomycin resistance|MEG_3587|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002365182.1|180|liaS_A180T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_LiaS|wt_coherence=TRUE MTDRISRRMISLYASLSTFIVILITLFSYFHSIKQNRWLLELLQRKVFYLPLIVHIVLISLLIGLLTFLLISLVQKGQYG RIEEKLRLLANGNYESPVLNKPTTSENQDHYLTEVEQDIWSIKNKLLEMSKELQLLNSRPQLMDGQTKEEILENERHRLA RELHDSVSQQLFAAMMMLSTLNEQAQRTETPEPYRKQLAMVAEIINASQSEMRALLLHLRPISLEGKSLRKGIEQLLKEL QTKIKIELIWDVEDVHLNSSIEDHLFRIVQELLSNTLRHAKAKELEVYLHQVDKNVLLRIVDDGVGFDMKEQSNKAGSYG LNNIRERVVGMGGTVKIISFKGQGTSVEIKVPVIKEETASDQSNVSG >98|I440S|ARO:3003797|Enterococcus faecalis YybT with mutation conferring daptomycin resistance|MEG_7843|Drugs|Lipopeptides|Daptomycin-resistant_mutant|YYBT|RequiresSNPConfirmation|Enterococcus_faecalis|WP_002356022.1|440|yybT_I440S|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_YybT|wt_coherence=TRUE MQKKRIQKNGFLIVVGLLLVEFLLYFLLTNKWLLLAVIIALDIFLLVVIRLLIRDVEITNVEKIQEASSIAEQSLDYVVN EVPVGIITYNGETRAVEWLNPYAASIFNKDNQLTLTASQVTSYLELAERNQDIFTIDENTYRFSVNKEQHTITFEDITKE SNLYQEKVEMQTAIGIVSVDNYDDVTDTMDEKEISYLNSFITTMVSDWMDQYKVFYKRINAERYFFIAQWEDIQKMMDEK FSILDTIRKESANHEVAITLSMGIAYGGPTLDQTGTTAQTNLDTALVRGGDQVVVKEAKDEAKPLFFGGKTAVTTKRSQV RSRAMSMAIKGIIAESADIYIMGHRYPDMDALGSAFGVARLASFNNRKAWIVLDENEIIPDVKRVLEAIKEYPELEERII SPKEAMKRKKESSLLVMVDYHKPSLSISQELYERFDKVVSIDHHRRGDEFPAKPLLSYIESSASSASELVTELIEYQSNS ANKLQAFEATMMLAGIVVDTKSFNTRTTARTFDVASYLRTCGADSSLVQYLLSSDLTSYLEMNNLISKSEYVTKDTVVVA GSEDKEYDSVTAAKTADTLLSMAGINAAFVITKRTDQQIGISARSNGSINVQIIMENLGGGGHFTNAAVQLSNVTVAEVK EQLLDVIRQNINEMYEQE >99|R218Q|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|218|cls_R218Q|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHQKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >100|K59T|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|59|cls_K59T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDTKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >101|H215R|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|215|cls_H215R|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYRDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >102|N13I|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|13|cls_N13I|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLIALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >103|N13T|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|13|cls_N13T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLTALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >104|A20D|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|20|cls_A20D|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVDILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >105|D27N|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|27|cls_D27N|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRNVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >106|G178T|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|178|cls_G178T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFTSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >107|R267H|ARO:3003092|Enterococcus faecium cls conferring resistance to daptomycin|MEG_1732|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289473.1|267|cls_R267H|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_Cls|wt_coherence=TRUE MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGVGFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRG DTIEHYDPDMGDKDKQQFVDFFSSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHRKIVVIDGKISYTGGFNIANQYV NTTKKFGYWRDTHIRIFGAASSLLQLHFLTDWNVSVPEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIK LSFIKLITSAKKRVWIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQILVYENGFL HAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKEDETHCSSMTTETVKEMSNWLLFKQQISRLFS PIL >108|G258A|ARO:3003438|Enterococcus faecium EF-Tu mutants conferring resistance to GE2270A|MEG_7303|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGMWCTLCTSYTYQTNKKYIVFLGGHFKMAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQAMAYDQIDG APEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIV VFLNKVDMVDDEELLELVEMEVRDLLTEYEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFM MPVEDVFSITGRGTVATARVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQ VLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIEN GTKFSIREGGRTVGAGVVTEIKA >109|G275A|ARO:3003438|Enterococcus faecium EF-Tu mutants conferring resistance to GE2270A|MEG_7303|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGMWCTLCTSYTYQTNKKYIVFLGGHFKMAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQAMAYDQIDG APEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIV VFLNKVDMVDDEELLELVEMEVRDLLTEYEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFM MPVEDVFSITGRGTVATGRVERGQVRVGDEVEVVAIAEETSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQ VLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIEN GTKFSIREGGRTVGAGVVTEIKA >110|L39F|ARO:3003790|Enterococcus faecium liaF mutant conferring daptomycin resistance|MEG_3591|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFFIYLAMRKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVL AVLFIGLKGVEISGIDLTKNAFWRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSSDYDENPRRLKIITNTLVGDVEV IRI >111|I144T|ARO:3003790|Enterococcus faecium liaF mutant conferring daptomycin resistance|MEG_3591|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002295408.1|144|liaF_I144T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaF|wt_coherence=TRUE MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAMRKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVL AVLFIGLKGVEISGIDLTKNAFWRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDTNIAIISGDTIIDLGNT LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSSDYDENPRRLKIITNTLVGDVEV IRI >112|W73C|ARO:3003078|Enterococcus faecium liaR mutant conferring daptomycin resistance|MEG_3590|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289153.1|73|liaR_W73C|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaR|wt_coherence=TRUE MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMTLRPDVILMDLVMEEMDGIESTKAILKDCPEAKIII VTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK >113|E192G|ARO:3003079|Enterococcus faecium liaS mutant conferring daptomycin resistance|MEG_3589|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289154.1|192|liaS_E192G|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaS|wt_coherence=TRUE MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLRARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYG KIEEKLRALSSGNYESKLLLLPIPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA RELHDSVSQQLFAAMMMMSALTEQAEKSETPGMFRKQLKMVAEIINASQSEMRALLLHLRPVNLEEKSLKQGIEQLLKEL QNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNTLRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLN NIKERVAGIGGTVKIISFKGQGTSVEIKVPLMKEA >114|A180T|ARO:3003079|Enterococcus faecium liaS mutant conferring daptomycin resistance|MEG_3589|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289154.1|180|liaS_A180T|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaS|wt_coherence=TRUE MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLRARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYG KIEEKLRALSSGNYESKLLLLPIPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA RELHDSVSQQLFAAMMMMSTLTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLHLRPVNLEEKSLKQGIEQLLKEL QNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNTLRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLN NIKERVAGIGGTVKIISFKGQGTSVEIKVPLMKEA >115|H264Q|ARO:3003079|Enterococcus faecium liaS mutant conferring daptomycin resistance|MEG_3589|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289154.1|264|liaS_H264Q|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaS|wt_coherence=TRUE MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLRARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYG KIEEKLRALSSGNYESKLLLLPIPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLHLRPVNLEEKSLKQGIEQLLKEL QNKIQISLKWDVEDVKLSSSIEDQLFRIVQELLSNTLRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLN NIKERVAGIGGTVKIISFKGQGTSVEIKVPLMKEA >116|T120A|ARO:3003079|Enterococcus faecium liaS mutant conferring daptomycin resistance|MEG_3589|Drugs|Lipopeptides|Daptomycin-resistant_mutant|LIAFSR|RequiresSNPConfirmation|Enterococcus_faecium|WP_002289154.1|120|liaS_T120A|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecium_daptomycin_resistant_LiaS|wt_coherence=TRUE MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLRARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYG KIEEKLRALSSGNYESKLLLLPIPSASDDLYIKDIDKEIAKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLHLRPVNLEEKSLKQGIEQLLKEL QNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNTLRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLN NIKERVAGIGGTVKIISFKGQGTSVEIKVPLMKEA >117|S352T|ARO:3003900|Escherichia coli cyaA with mutation conferring resistance to fosfomycin|NA|NA|NA|NA|NA|NA|Escherichia|WP_000281668.1|352|cyaA_S352T|FOSMIDOMYCIN|FOSMIDOMYCIN|Escherichia_fosmidomycin_resistant_CyaA|wt_coherence=TRUE MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELY RGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENR FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFT RLDLVRRCFYLKVCEKLSRERACVGWRRAVLTQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRF ARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQ PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEY DPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVF CYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV QVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSF INFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS >118|A376V|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|376|tufA_A376V|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFVIREGGRTVGAGVVAKVLG >119|Y161C|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|161|tufA_Y161C|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ CDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >120|Q125K|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|125|tufA_Q125K|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRKVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >121|G317D|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|317|tufA_G317D|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEDGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >122|Q125R|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|125|tufA_Q125R|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRRVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >123|Y161D|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|161|tufA_Y161D|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ DDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >124|Y161N|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|161|tufA_Y161N|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ NDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >125|L121Q|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|121|tufA_L121Q|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHIQLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >126|A376S|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|376|tufA_A376S|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFSIREGGRTVGAGVVAKVLG >127|Q125E|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|125|tufA_Q125E|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGREVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >128|E379K|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|379|tufA_E379K|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIRKGGRTVGAGVVAKVLG >129|Q330H|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|330|tufA_Q330H|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPHFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >130|A376T|ARO:3003368|Escherichia coli EF-Tu mutants conferring resistance to kirromycin|MEG_7302|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|Escherichia|WP_000031783.1|376|tufA_A376T|POLYKETIDE|KIRROMYCIN|Escherichia_kirromycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFTIREGGRTVGAGVVAKVLG >131|R234S|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVSSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >132|R234F|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >133|R334C|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGCHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >134|T336A|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGRHAPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >135|R231V|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIVDVFSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >136|R231C|ARO:3003369|Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin|MEG_7301|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSPEGESTIVRNIAVSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINT SHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEE LLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPICDVFSISGRG TVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKF ESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVG AGVVAKVLG >137|P64A|ARO:3003386|Escherichia coli folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|64|folP_P64A|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRAGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >138|P64H|ARO:3003386|Escherichia coli folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|64|folP_P64H|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRHGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >139|P64L|ARO:3003386|Escherichia coli folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|64|folP_P64L|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRLGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >140|P64R|ARO:3003386|Escherichia coli folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|64|folP_P64R|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRRGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >141|P64S|ARO:3003386|Escherichia coli folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|64|folP_P64S|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRSGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >142|E448K|ARO:3003889|Escherichia coli GlpT with mutation conferring resistance to fosfomycin|MEG_3144|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSK FIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELT AKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGN RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAA SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG >143|A67S|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSSRVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >144|A84P|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSPVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >145|S83L|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDLAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >146|S83W|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDWAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >147|D87V|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYVTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >148|Q106H|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGHGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >149|G81C|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH CDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >150|S83I|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDIAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >151|D87Y|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYYTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >152|D87H|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYHTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >153|D87G|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYGTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >154|D87N|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >155|S83F|ARO:3004335|Escherichia coli gyrA with mutation conferring resistance to triclosan|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDFAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >156|R136H|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136H|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQHEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >157|R136S|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136S|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQSEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >158|R136L|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136L|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQLEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >159|R136E|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136E|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQEEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >160|R136I|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136I|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQIEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >161|R136G|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136G|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQGEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >162|R136C|ARO:3003303|Escherichia coli gyrB conferring resistance to aminocoumarin|MEG_3244|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Escherichia|WP_000072067.1|136|gyrB_R136C|AMINOCOUMARIN|AMINOCOUMARIN|Escherichia_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQCEGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >163|D369N|ARO:3003775|Escherichia coli murA with mutation conferring resistance to fosfomycin|MEG_4095|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATNLRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKGE >164|C115S|ARO:3003775|Escherichia coli murA with mutation conferring resistance to fosfomycin|MEG_4095|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Escherichia|WP_000357259.1|115|murA_C115S|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGSTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKGE >165|C115E|ARO:3003775|Escherichia coli murA with mutation conferring resistance to fosfomycin|MEG_4095|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Escherichia|WP_000357259.1|115|murA_C115E|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGETIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKGE >166|L370I|ARO:3003775|Escherichia coli murA with mutation conferring resistance to fosfomycin|MEG_4095|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Escherichia|WP_000357259.1|370|murA_L370I|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDIRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKGE >167|C115D|ARO:3003775|Escherichia coli murA with mutation conferring resistance to fosfomycin|MEG_4095|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Escherichia|WP_000357259.1|115|murA_C115D|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGDTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKGE >168|R15C|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSICHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >169|R203L|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTLGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >170|R203C|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTCGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >171|S33R|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINRARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >172|G131D|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGDLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >173|R133S|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLSNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >174|E84G|ARO:3003308|Escherichia coli parC conferring resistance to fluoroquinolones|MEG_5333|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|Escherichia|WP_001281881.1|84|parC_E84G|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYGAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >175|S80I|ARO:3003308|Escherichia coli parC conferring resistance to fluoroquinolones|MEG_5333|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|Escherichia|WP_001281881.1|80|parC_S80I|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDI ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >176|D476N|ARO:3003316|Escherichia coli parE conferring resistance to fluoroquinolones|MEG_5394|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PAREF|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDNLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >177|V25I|ARO:3003899|Escherichia coli PtsI with mutation conferring resistance to fosfomycin|MEG_5819|Drugs|Fosfomycin|Fosfomycin_target_mutation|PTSL|RequiresSNPConfirmation|Escherichia|WP_000623140.1|25|ptsI_V25I|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_PtsI|wt_coherence=TRUE MISGILASPGIAFGKALLLKEDEIIIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR AVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAV AEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAIRIAMDRREILRDQLRAILRASAFGKLRIMFPMIISVEEVR ALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPS VLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDE LMTLVNKFIEEKTIC >178|R687H|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|687|rpoB_R687H|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQHQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >179|H526Y|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|526|rpoB_H526Y|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITYKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >180|Q513P|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|513|rpoB_Q513P|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSPFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >181|V146F|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|146|rpoB_V146F|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIFSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >182|Q513L|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|513|rpoB_Q513L|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSLFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >183|P564L|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|564|rpoB_P564L|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETLEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >184|T563P|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|563|rpoB_T563P|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IEPPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >185|L533P|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|533|rpoB_L533P|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISAPGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >186|S531F|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|531|rpoB_S531F|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRIFALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >187|R529S|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|529|rpoB_R529S|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRSISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >188|R529C|ARO:3003288|Escherichia coli rpoB mutants conferring resistance to rifampicin|MEG_6094|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|Escherichia|WP_000263098.1|529|rpoB_R529C|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRCISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >189|G97D|ARO:3003893|Escherichia coli UhpA with mutation conferring resistance to fosfomycin|NA|NA|NA|NA|NA|NA|Escherichia|WP_000633668.1|97|uhpA_G97D|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_UhpA|wt_coherence=TRUE MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV HDSPALVEQALNAGARDFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW >190|E350Q|ARO:3003890|Escherichia coli UhpT with mutation conferring resistance to fosfomycin|MEG_7330|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Escherichia|WP_000879194.1|350|uhpT_E350Q|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_UhpT|wt_coherence=TRUE MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGV GKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPESYGLGKAEELFGEEISEEDKET ESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRIGIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSD LANGRRGLVACIALALIIATLGVYQHASNQYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGD SFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERKIRREKKIQQLTVA >191|S357N|ARO:3004446|Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics|MEG_5408|Drugs|betalactams|Penicillin_binding_protein|PBP3|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKFNSSRKSGKSKKTIRKLTAPETVKQNKPQKVFEKCFMRGRYMLSTVLILLGLCALVARAAYVQSINADTLSNEADKR SLRKDEVLSVRGSILDRNGQLLSVSVPMSAIVADPKTMLKENSLADKERIAALAEELGMTENDLVKKIEKNSKSGYLYLA RQVELSKANYIRRLKIKGIILETEHRRFYPRVEEAAHVVGYTDIDGNGIEGIEKSFNSLLVGKDGSRTVRKDKRGNIVAH ISDEKKYDAQDVTLSIDEKLQSMVYREIKKAVSENNAESGTAVLVDVRTGEVLAMATAPSYNPNNRVGVKSELMRNRAIT DTFEPGSTVKPFVVLTALQRGVVKRDEIIDTTSFKLNGKEIVDVAPRAQQTLDEILMNSSNRGVSRLALRMPPSALMETY QNAGLSKPTDLGLIGEQVGILNANRKRWADIERATVAYGYGITATPLQIARAYATLGSFGVYRPLSITKVDPPVIGKRVF SEKITKDIVGILEKVAIKNKRAMVEGYRVGVKTGTARKIENGHYVNKYVAFTAGIAPISDPRYALVVLINDPKAGEYYGG AVSAPVFSNIMGYALRANAIPQDAEAAENTTTKSAKRIVYIGEHKNQKVN >192|L389F|ARO:3004446|Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics|MEG_5408|Drugs|betalactams|Penicillin_binding_protein|PBP3|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKFNSSRKSGKSKKTIRKLTAPETVKQNKPQKVFEKCFMRGRYMLSTVLILLGLCALVARAAYVQSINADTLSNEADKR SLRKDEVLSVRGSILDRNGQLLSVSVPMSAIVADPKTMLKENSLADKERIAALAEELGMTENDLVKKIEKNSKSGYLYLA RQVELSKANYIRRLKIKGIILETEHRRFYPRVEEAAHVVGYTDIDGNGIEGIEKSFNSLLVGKDGSRTVRKDKRGNIVAH ISDEKKYDAQDVTLSIDEKLQSMVYREIKKAVSENNAESGTAVLVDVRTGEVLAMATAPSYNPNNRVGVKSELMRNRAIT DTFEPGSTVKPFVVLTALQRGVVKRDEIIDTTSFKLSGKEIVDVAPRAQQTLDEILMNSSNRGVSRLAFRMPPSALMETY QNAGLSKPTDLGLIGEQVGILNANRKRWADIERATVAYGYGITATPLQIARAYATLGSFGVYRPLSITKVDPPVIGKRVF SEKITKDIVGILEKVAIKNKRAMVEGYRVGVKTGTARKIENGHYVNKYVAFTAGIAPISDPRYALVVLINDPKAGEYYGG AVSAPVFSNIMGYALRANAIPQDAEAAENTTTKSAKRIVYIGEHKNQKVN >193|D350N|ARO:3004446|Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics|MEG_5408|Drugs|betalactams|Penicillin_binding_protein|PBP3|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKFNSSRKSGKSKKTIRKLTAPETVKQNKPQKVFEKCFMRGRYMLSTVLILLGLCALVARAAYVQSINADTLSNEADKR SLRKDEVLSVRGSILDRNGQLLSVSVPMSAIVADPKTMLKENSLADKERIAALAEELGMTENDLVKKIEKNSKSGYLYLA RQVELSKANYIRRLKIKGIILETEHRRFYPRVEEAAHVVGYTDIDGNGIEGIEKSFNSLLVGKDGSRTVRKDKRGNIVAH ISDEKKYDAQDVTLSIDEKLQSMVYREIKKAVSENNAESGTAVLVDVRTGEVLAMATAPSYNPNNRVGVKSELMRNRAIT DTFEPGSTVKPFVVLTALQRGVVKRDEIINTTSFKLSGKEIVDVAPRAQQTLDEILMNSSNRGVSRLALRMPPSALMETY QNAGLSKPTDLGLIGEQVGILNANRKRWADIERATVAYGYGITATPLQIARAYATLGSFGVYRPLSITKVDPPVIGKRVF SEKITKDIVGILEKVAIKNKRAMVEGYRVGVKTGTARKIENGHYVNKYVAFTAGIAPISDPRYALVVLINDPKAGEYYGG AVSAPVFSNIMGYALRANAIPQDAEAAENTTTKSAKRIVYIGEHKNQKVN >194|V562L|ARO:3004446|Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics|MEG_5408|Drugs|betalactams|Penicillin_binding_protein|PBP3|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKFNSSRKSGKSKKTIRKLTAPETVKQNKPQKVFEKCFMRGRYMLSTVLILLGLCALVARAAYVQSINADTLSNEADKR SLRKDEVLSVRGSILDRNGQLLSVSVPMSAIVADPKTMLKENSLADKERIAALAEELGMTENDLVKKIEKNSKSGYLYLA RQVELSKANYIRRLKIKGIILETEHRRFYPRVEEAAHVVGYTDIDGNGIEGIEKSFNSLLVGKDGSRTVRKDKRGNIVAH ISDEKKYDAQDVTLSIDEKLQSMVYREIKKAVSENNAESGTAVLVDVRTGEVLAMATAPSYNPNNRVGVKSELMRNRAIT DTFEPGSTVKPFVVLTALQRGVVKRDEIIDTTSFKLSGKEIVDVAPRAQQTLDEILMNSSNRGVSRLALRMPPSALMETY QNAGLSKPTDLGLIGEQVGILNANRKRWADIERATVAYGYGITATPLQIARAYATLGSFGVYRPLSITKVDPPVIGKRVF SEKITKDIVGILEKVAIKNKRAMVEGYRVGVKTGTARKIENGHYVNKYVAFTAGIAPISDPRYALVVLINDPKAGEYYGG ALSAPVFSNIMGYALRANAIPQDAEAAENTTTKSAKRIVYIGEHKNQKVN >195|S385T|ARO:3004446|Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics|MEG_5408|Drugs|betalactams|Penicillin_binding_protein|PBP3|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKFNSSRKSGKSKKTIRKLTAPETVKQNKPQKVFEKCFMRGRYMLSTVLILLGLCALVARAAYVQSINADTLSNEADKR SLRKDEVLSVRGSILDRNGQLLSVSVPMSAIVADPKTMLKENSLADKERIAALAEELGMTENDLVKKIEKNSKSGYLYLA RQVELSKANYIRRLKIKGIILETEHRRFYPRVEEAAHVVGYTDIDGNGIEGIEKSFNSLLVGKDGSRTVRKDKRGNIVAH ISDEKKYDAQDVTLSIDEKLQSMVYREIKKAVSENNAESGTAVLVDVRTGEVLAMATAPSYNPNNRVGVKSELMRNRAIT DTFEPGSTVKPFVVLTALQRGVVKRDEIIDTTSFKLSGKEIVDVAPRAQQTLDEILMNSSNRGVTRLALRMPPSALMETY QNAGLSKPTDLGLIGEQVGILNANRKRWADIERATVAYGYGITATPLQIARAYATLGSFGVYRPLSITKVDPPVIGKRVF SEKITKDIVGILEKVAIKNKRAMVEGYRVGVKTGTARKIENGHYVNKYVAFTAGIAPISDPRYALVVLINDPKAGEYYGG AVSAPVFSNIMGYALRANAIPQDAEAAENTTTKSAKRIVYIGEHKNQKVN >196|S84Y|ARO:3003924|Haemophilus parainfluenzae gyrA conferring resistance to fluoroquinolones|MEG_3184|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDSIHSSITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFSMDQSGITAGKKYVKSARVVGDVIGKYHP HGDYAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDAPAAMRYTEVRMQKITQALLTDLDKETVNFSPNYDGELMIPDVL PTRIPALLANGSSGIAVGMATNIPPHNLNEVLDGCLAYIDNENITIDELMQYIPGPDFPTAALINGRKGIEEAYRTGRGK VYVRARASVETTDKGKEQIIVTELPYQVNKAKLVEKIAELIKDKKIEGISNIIDLSNKEGIRIEIDIKRDAVGEVVLNHL YALTQMQVTFGINMVALDHGQPRLFNLKQIIEAFVMHRREVVIRRSLFELRKARERTHILEGLAVATSNIDEIIDIIRQS KERKEAAEKLISRPWKLNNEILGLLDAAARPAELAAEFGIKGSDYYLSPEQVDAILELRLHRLTGLATEEVINEYKELLV KIAELLHIINSPERLMEVIREELEQVRAQFADERRTEITAASGDIDLEDLIAQEDVVVTLSHEGYVKYQPLTDYEAQRRG GKGKSATKMKDEDFIEKLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLQENERITAILPISAYEED KFVIMATAGGIVKKIALTEFSRPRSSGIIALNLRDEDELIGVDITDGSNEIMLFSSQGRVVRFAESAVRAMGRLATGVRG IKLALTNDIADDESAVEIEEVSDDNAEETLDLNIDKVVSLVVPKNDGAILTATQNGYGKRTQLSEYPTKSRNTKGVISIK VSERNGKVVAATQVEETDQIMLITDAGTLVRTRVSEVSIVGRNTQGVRLIRTAEDEHVVSLERVCDVDDEDEGTEDVTSE E >197|S84F|ARO:3003925|Haemophilus parainfluenzae parC conferring resistance to fluoroquinolones|MEG_3251|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNINYEGIEQMPLRTFTEKAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNAAAKFKKSARTVGDVLGKFHP HGDFACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKISEILLSELGQGTVDFQPNFDGTLEEPQY LPARLPHILLNGTTGIAVGMATDIPPHNINEVADAAVMLLDNPKAGLDDVLNIIQGPDFPTEAEIISPKDDIRKMYETGR GSIKMRATWHKEDGEIIISALPHQSSPSKIIAQIAEQMTAKKLPMVEDIRDEADYENPVRIVLVPRSNRVDTDALMAHLF ATTDLEKSYRVNMNMIGLDHKPAVKGLLQVLIEWLTFRRTTVTRRLQHRLDKVLARLHILDGLMIAFLNIDEVIEIIRTE DEPKQVLMARFNLSDEQAEAILNLRLRHLAKLEEHQLQAEKDKLEEERSNLELILGSERRLNTLIKKEIQEDAKKYASPR MSQLVEREEAKAISESEMTPAEPVTVILSEMGWVRCAKGHDIDPEGLSYKAGDKYLAHACGKSNQPVIFIDSTGRSYALD PLSLPSARSQGEPLTGKLTLPAGATIEQVIMEPEKQELLMASDAGYGFICKFEDLIARNKAGKALISLPENAKVLKPETL SESTSLLVSLTSAGRMLIFPVRDLPALSKGKGNKIISIPAANAKARSELLVKLFLISEQASLEFHSGKRKITLKPEDLQK FRAERGRKGSQLPRGLHSNVDIVVVEPEHNS >198|R45C|ARO:3003374|Klebsiella aerogenes acrR with mutation conferring multidrug antibiotic resistance|MEG_413|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_RND_efflux_regulator|ACRR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARKTKQQALETRQLILDVALRLFSQQGVSSTSLAAIAKAAGVTCGAIYWHFKNKSDLFNEIWSLSDASISDLEVEYRAK FPNDPLSVVREILVYILEATVVEERRRLMMEIIFHKCEFVGEMAVVQQAQRSLWLESYDRIEQTLKDCITAQQLPANLLT RRAAILMRSYLSGLMENWLFAPESFNLHAEARAYVDALIEMYQTCPSLRSSSEVMA >199|G133D|ARO:3003385|Klebsiella aerogenes Omp36|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKIDGLHYFSSDDSVDGDQTYMRIGVKGETQINDQLTGYGQWEYN VQANNTESSSDQAWTRLAFAGLKFGDAGSFDYGRNYGVVYDVTSWTDVLPEFDGDTYGSDNFLQSRANGVATYRNSDFFG LVDGLNFALQYQGKNGSVSGEDQTNNGRDFQKQNGEGFGTSVTYDIWDGISAGFAYSSSKRTDEQNNSTFVSKTDGGRYG VLGEGDHAETYTGGLKYDANNIYLATQYTQTYNATRTGNIGFANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKDMGRYGD QDILKYVDLGATYYFNKNMSTYVDYKINLLDDNKFTKDASISTDNVVALGLVYQF >200|D191Y|ARO:3003585|Klebsiella mutant PhoP conferring antibiotic resistance to colistin|MEG_5783|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_ABC_efflux_regulator|PHOB|RequiresSNPConfirmation|Klebsiella|WP_004150807.1|191|phoP_D191Y|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoP|wt_coherence=TRUE MRVLVVEDNALLRHHLKVQLQELGHQVDAAEDAREADYYLGEHLPDIAIVDLGLPDEDGLSLIRRWRSHDVSLPVLVLTA REGWQDKVEVLSAGADDYVTKPFHIEEVAARMQALLRRNSGLASQVISLPPFQVDLSRRELSVNDQPIKLTAFEYTIMET LIRNRGKVVSKDSLMLQLYPDAELRESHTIYVLMGRLRKKIQAEYPQDVITTVRGQGYLFELR >201|V165I|ARO:3003373|Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance|MEG_414|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_RND_efflux_regulator|ACRR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARKTKQQARETRQLILDVALRLFSQQGVSSTSLATIAKAAGVTRGAIYWHFKNKSDLFNEIWELSDASISDLEIEYRAK FPNDPLSVIREILVYVLEATVTEERRRLMMEIIYHKCEFVGEMTVVQQAQRQLSLASYERIEQTLKECIAAKLLPANLLT RRAAILMRSYLSGLMENWLFAPDSFDLHAEARDYVAILLEMYQFCPTLRGPESLSA >202|Y114F|ARO:3003373|Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance|MEG_414|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_RND_efflux_regulator|ACRR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARKTKQQARETRQLILDVALRLFSQQGVSSTSLATIAKAAGVTRGAIYWHFKNKSDLFNEIWELSDASISDLEIEYRAK FPNDPLSVIREILVYVLEATVTEERRRLMMEIIFHKCEFVGEMTVVQQAQRQLSLASYERIEQTLKECIAAKLLPANLLT RRAAVLMRSYLSGLMENWLFAPDSFDLHAEARDYVAILLEMYQFCPTLRGPESLSA >203|M109I|ARO:3003373|Klebsiella pneumoniae acrR with mutation conferring multidrug antibiotic resistance|MEG_414|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_RND_efflux_regulator|ACRR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARKTKQQARETRQLILDVALRLFSQQGVSSTSLATIAKAAGVTRGAIYWHFKNKSDLFNEIWELSDASISDLEIEYRAK FPNDPLSVIREILVYVLEATVTEERRRLIMEIIYHKCEFVGEMTVVQQAQRQLSLASYERIEQTLKECIAAKLLPANLLT RRAAVLMRSYLSGLMENWLFAPDSFDLHAEARDYVAILLEMYQFCPTLRGPESLSA >204|K5E|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPESEDKKQALLEAATAAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >205|I88N|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEAATAAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNNWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >206|A16D|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEDATAAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >207|G96D|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEAATAAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWDVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >208|T162I|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEAATAAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TIIEFASHDPQRAREIIALGFEAMWHALHEADA >209|T43M|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEAATAAFAQSGIAASTSAIARSAGVAEGMLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >210|A19V|ARO:3003380|Klebsiella pneumoniae ramR mutants|MEG_6045|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARPKSEDKKQALLEAATVAFAQSGIAASTSAIARSAGVAEGTLFRYFATKDELLNELYLAIKLRLVRTMIAGLDPDEKR PKENARNIWNSYIDWGVRNPMEHKAIRRMALSERITDETRRQVKESFPELNEMCQLSVKEIFLSEAYRAFGDALFLSLAE TTIEFASHDPQRAREIIALGFEAMWHALHEADA >211|Q52P|ARO:3003028|lmrA|MEG_3594|Drugs|Multi-drug_resistance|Multi-drug_ABC_efflux_pumps|LMRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSVFARATSLFSRAARTRAADEAARSRSRWVTLVFLAVLQLLIAVDVTVVNPALPAIRDSFHVDTRQLTWVVTGYTVVGG GLLMVGGRIADLFGRRRTLLFGAFLFGASSLAAGLAPNLELLVLARFGQGAGEALSLPAAMSLIACSSRTAPFQGVERLA SVASVGLVLGFLLSGVITQLFSWRWIFLINIPLVSLVLVAVLLLVKKDETTARNPVDLPGALLFTAAPLLLIFGVNELGE DEPRLPLAVGSLLAAAVCAAAFVAVERRTAHPLVPLTFFGNRVRLVANGATVLLSAALSTSFFLLTMHLQEERDLSPIEA GLSFLPLGLSLILACVLVRGLIERIGTTGAAVLGMALAGPRHRLFALLPSDNSLLTSVFPGMILLLRMATGLVALQNAAL HAVTEADAGVASGVQRCADQLGGASGIAVYVSIGFSPHLGGDWDPFTVAYSLAGIGLIAAVLAVLALSPDRRLAAPREQE D >212|Q72K|ARO:3003573|LpxA|MEG_3626|Drugs|Lipopeptides|Colistin-resistant_mutant|LPXA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCKDLKYKGEE TWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQ FCKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL PSVPEAQLLIDSLEQSERGIVR >213|H159D|ARO:3003573|LpxA|MEG_3626|Drugs|Lipopeptides|Colistin-resistant_mutant|LPXA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQDLKYKGEE TWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIDQ FCKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL PSVPEAQLLIDSLEQSERGIVR >214|G68D|ARO:3003573|LpxA|MEG_3626|Drugs|Lipopeptides|Colistin-resistant_mutant|LPXA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNHDLIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVDEVCQDLKYKGEE TWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQ FCKIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIFKSGLTSVQAIDQIKSEIL PSVPEAQLLIDSLEQSERGIVR >215|P30L|ARO:3003574|LpxC|MEG_3627|Drugs|Lipopeptides|Colistin-resistant_mutant|LPXC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVKQRTLNRVVKASGIGLHSGQKVMINFILHTVDGGIVFRRIDLDPPVDIPANALLIQEAFMCSNLVTGDIKVGTIEHVM SAIAGLGIDNLIVEVSASEVPIMDGSAGPFIYLLMQGGLREQDAPKKFIKILKPVEALIDDKKAIFSPHNGFQLNFTIDF DHPAFAKEYQSATIDFSTETFVYEVSEARTFGFMKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKIL DAVGDLYLLGHQIIAKFDGYKSGHALNNQLLRNVQSDPSNYEIVTFDDEKDCPIPYVSVT >216|S464Y|ARO:3003306|Morganella morganii gyrB conferring resistance to fluoroquinolones|MEG_3242|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGYCKDIIVTIHNDNSVSVQDDGRGIPT GIHEEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSEKLELVIRRDGKVHEQIYRHGEPQDRLTVVGET DKTGTRVRFWPSMDTFKGETEFQYDILAKRLRELSFLNSGVSIRLIDKRDGKEDHFHYEGGIKAFVEYLSRAKTSIHNNV FYFSTEKDDIGVEISMQWNDSFQENVYCFTNNIPQRDGGAHLAGFRAAMTRTLNSYIEKEGLNKKSKVSTTGDDAREGLV AVISVKVPDPKFSSQTKDKLVSSEVKTAVETLMNEKLSEYLDENPNDTKIIVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPAFSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLAYQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIIERGYVYIAQPPLYKVKKGKQEQYIKDDEAMEQYQVSIA LDGAALYVNENAAPIQGEHLEKLLHEYNGAHKIIRRLERLYPLALLNSLVYQPKLEESALLNKTEVEAWAQSLTERLTRH EEHGSTYSYRIAENKERQLFEPVLTIRTHGVDTDYNLDFDFVHGSEYARISKLGELIRGLIEEGAYVVRGERRQNVSNFE QALDWLMKESRRGLAVQRYKGLGEMNPEQLWETTMNPETRRMLQVTVKDAIATDQLFTTLMGDDVEPRRAFIEENALKAA NIDV >217|S464A|ARO:3003306|Morganella morganii gyrB conferring resistance to fluoroquinolones|MEG_3242|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGYCKDIIVTIHNDNSVSVQDDGRGIPT GIHEEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSEKLELVIRRDGKVHEQIYRHGEPQDRLTVVGET DKTGTRVRFWPSMDTFKGETEFQYDILAKRLRELSFLNSGVSIRLIDKRDGKEDHFHYEGGIKAFVEYLSRAKTSIHNNV FYFSTEKDDIGVEISMQWNDSFQENVYCFTNNIPQRDGGAHLAGFRAAMTRTLNSYIEKEGLNKKSKVSTTGDDAREGLV AVISVKVPDPKFSSQTKDKLVSSEVKTAVETLMNEKLSEYLDENPNDTKIIVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPAFSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLAAQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIIERGYVYIAQPPLYKVKKGKQEQYIKDDEAMEQYQVSIA LDGAALYVNENAAPIQGEHLEKLLHEYNGAHKIIRRLERLYPLALLNSLVYQPKLEESALLNKTEVEAWAQSLTERLTRH EEHGSTYSYRIAENKERQLFEPVLTIRTHGVDTDYNLDFDFVHGSEYARISKLGELIRGLIEEGAYVVRGERRQNVSNFE QALDWLMKESRRGLAVQRYKGLGEMNPEQLWETTMNPETRRMLQVTVKDAIATDQLFTTLMGDDVEPRRAFIEENALKAA NIDV >218|G45D|ARO:3000817|mtrR|MEG_4088|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_MFS_efflux_regulator|MTRR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRDALYWHFKNKEDLFDALFQRICDDIENCIAQDAADA EGGSWTVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE TAVIFIKSTLDGLIWRWFSSGESFDLGKTAPRIIGIMMDNLENHPCLRRK >219|P55R|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRRGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >220|P55L|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRLGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >221|P55S|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRSGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >222|V48F|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDFGGESTRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >223|V48A|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDAGGESTRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >224|V48G|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDGGGESTRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >225|R54G|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTGPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >226|T53I|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESIRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >227|T53A|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESARPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >228|T53P|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESPRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >229|T53N|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESNRPGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >230|P55T|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRTGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >231|P55A|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRAGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >232|P55H|ARO:3003389|Mycobacterium leprae folP with mutation conferring resistance to dapsone|MEG_2935|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRHGAIRTDPRVELSRIVPVVKELAAQG ITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLVAEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAG VDQAVAAGVDPGSLVIDPGLGFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG >233|D464N|ARO:3003304|Mycobacterium leprae gyrB conferring resistance to fluoroquinolones|MEG_3239|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAAQRKAQDEYGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAGYATQVDVRLFDDGSVEVADNG RGIPVAVHATGVPTVDVVMTQLHAGGKFGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPGILK QGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTINLVDERVKQDEVVDDVVSDTAEAPVAMTVEEKS TESSAPHKVRHRTFHYPGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHTFANTINTHEGGTHE EGFRSALTSVVNKYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFE ANPVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGGLPGKLADCRSTDPRSSELYVVEGNSAGGSAKSGRDSMFQA ILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIE HGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETGLKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVT LDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >234|E504V|ARO:3003304|Mycobacterium leprae gyrB conferring resistance to fluoroquinolones|MEG_3239|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAAQRKAQDEYGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAGYATQVDVRLFDDGSVEVADNG RGIPVAVHATGVPTVDVVMTQLHAGGKFGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPGILK QGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTINLVDERVKQDEVVDDVVSDTAEAPVAMTVEEKS TESSAPHKVRHRTFHYPGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHTFANTINTHEGGTHE EGFRSALTSVVNKYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFE ANPVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGGLPGKLADCRSTDPRSSELYVVEGDSAGGSAKSGRDSMFQA ILPLRGKIINVEKARIDRVLKNTVVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIE HGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETGLKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVT LDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >235|N502D|ARO:3003304|Mycobacterium leprae gyrB conferring resistance to fluoroquinolones|MEG_3239|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAAQRKAQDEYGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAGYATQVDVRLFDDGSVEVADNG RGIPVAVHATGVPTVDVVMTQLHAGGKFGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPGILK QGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTINLVDERVKQDEVVDDVVSDTAEAPVAMTVEEKS TESSAPHKVRHRTFHYPGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHTFANTINTHEGGTHE EGFRSALTSVVNKYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFE ANPVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGGLPGKLADCRSTDPRSSELYVVEGDSAGGSAKSGRDSMFQA ILPLRGKIINVEKARIDRVLKDTEVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIE HGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETGLKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVT LDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >236|S456L|ARO:3003284|Mycobacterium leprae rpoB mutations conferring resistance to rifampicin|MEG_6091|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDL KPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMM TEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKL GLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVV RERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLLALGPGGLSRERAGLEVRDVHPSHY GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVL VRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGH VVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGD ILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKIS DGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDK IHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPES FKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA >237|V472I|ARO:3003284|Mycobacterium leprae rpoB mutations conferring resistance to rifampicin|MEG_6091|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDL KPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMM TEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKA LGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKL GLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVV RERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEIRDVHPSHY GRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVL VRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGH VVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLL VAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGD ILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKIS DGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLP EELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDK IHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPES FKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA >238|D4N|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHNGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >239|G350D|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPDPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >240|A462V|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAVLSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >241|D833A|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLAPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >242|G5S|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDSNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >243|P913S|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFSIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >244|A201T|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGTLKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA GVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >245|G321S|ARO:3003453|Mycobacterium tuberculosis embA mutant conferring resistance to ethambutol|MEG_2709|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPHDGNERSHRIARLAAVVSGIAGLLLCGIVPLLPVNQTTATIFWPQGSTADGNITQITAPLVSGAPRALDISIPCSAIA TLPANGGLVLSTLPAGGVDTGKAGLFVRANQDTVVVAFRDSVAAVAARSTIAAGGCSALHIWADTGGAGADFMGIPGGAG TLPPEKKPQVGGIFTDLKVGAQPGLSARVDIDTRFITTPGALKKAVMLLGVLAVLVAMVGLAALDRLSRGRTLRDWLTRY RPRVRVGFASRLADAAVIATLLLWHVIGATSSDDGYLLTVARVAPKAGYVANYYRYFGTTEAPFDWYTSVLAQLAAVSTA SVWMRLPATLAGIACWLIVSRFVLRRLGPGPGGLASNRVAVFTAGAVFLSAWLPFNNGLRPEPLIALGVLVTWVLVERSI ALGRLAPAAVAIIVATLTATLAPQGLIALAPLLTGARAIAQRIRRRRATDGLLAPLAVLAAALSLITVVVFRDQTLATVA ESARIKYKVGPTIAWYQDFLRYYFLTVESNVEGSMSRRFAVLVLLFCLFGVLFVLLRRGRVAGLASGPAWRLIGTTAVGL LLLTFTPTKWAVQFGAFAGLAGVLGAVTAFTFARIGLHSRRNLTLYVTALLFVLAWATSGINGWFYVGNYGVPWYDIQPV IASHPVTSMFLTLSILTGLLAAWYHFRMDYAGHTEVKDNRRNRILASTPLLVVAVIMVAGEVGSMAKAAVFRYPLYTTAK ANLTALSTGLSSCAMADDVLAEPDPNAGMLQPVPGQAFGPDGPLGGISPVGFKPEGVGEDLKSDPVVSKPGLVNSDASPN KPNAAITDSAGTAGGKGPVGINGSHAALPFGLDPARTPVMGSYGENNLAATATSAWYQLPPRSPDRPLVVVSAAGAIWSY KEDGDFIYGQSLKLQWGVTGPDGRIQPLGQVFPIDIGPQPAWRNLRFPLAWAPPEADVARIVAYDPNLSPEQWFAFTPPR VPVLESLQRLIGSATPVLMDIATAANFPCQRPFSEHLGIAELPQYRILPDHKQTAASSNLWQSSSTGGPFLFTQALLRTS TIATYLRGDWYRDWGSVEQYHRLVPADQAPDAVVEEGVITVPGWGRPGPIRALP >246|Y319D|ARO:3003465|Mycobacterium tuberculosis embB with mutation conferring resistance to rifampicin|MEG_7259|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNDF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >247|Y333H|ARO:3003465|Mycobacterium tuberculosis embB with mutation conferring resistance to rifampicin|MEG_7259|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWHYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >248|P375A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGAAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >249|D328G|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEGPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >250|D328Y|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEYPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >251|F330V|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPVGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >252|G406A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEAIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >253|L413P|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSPVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >254|S297A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANASDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >255|D299E|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSEDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >256|M306L|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGLARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >257|M306V|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGVARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >258|M306I|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGIARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >259|M306T|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGTARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >260|D311H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVAHHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >261|E504Q|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLQATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >262|R507G|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATGVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >263|D1024N|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLNTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >264|Y319C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNCF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >265|Y333C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWCYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >266|Y319N|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNNF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >267|T630I|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLIALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >268|M1000R|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPRLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >269|D959A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEAW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >270|G745D|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVDGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >271|Q497K|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADKTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >272|Q497R|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADRTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >273|R471P|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHPLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >274|R469P|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRPHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >275|I465D|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRDLVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >276|R460C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGCPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >277|P446H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQHTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >278|G406D|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEDIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >279|G406C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPECIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >280|G406S|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPESIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >281|N399H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFHN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >282|P397Q|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMQFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >283|S380R|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEARKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >284|E378A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >285|L239P|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRPD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >286|D240H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLH QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >287|Y334H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYHNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >288|A356V|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLVAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >289|A357S|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLASGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >290|E368A|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSRAVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >291|Q379R|ARO:3003455|Mycobacterium tuberculosis embR mutant conferring resistance to ethambutol|MEG_2713|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLR KLLGGAGIDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVE PFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLG IDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVL DSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFRISAGTHGGT >292|C110Y|ARO:3003455|Mycobacterium tuberculosis embR mutant conferring resistance to ethambutol|MEG_2713|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLR KLLGGAGIDPRVVLAAAPPGYRLSIPDNTYDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVE PFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLG IDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVL DSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT >293|P28S|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCSTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >294|L35R|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAIREKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >295|G42D|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMDGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >296|D56Y|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSYSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >297|D58G|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSGMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >298|W69C|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPCTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >299|H102P|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHPKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >300|Y141N|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYNNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >301|T186P|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGAPAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >302|T189R|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVRLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >303|S329P|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNPGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >304|A341V|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITVTGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >305|N345K|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLKLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >306|A352E|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGETATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >307|M372R|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGRMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >308|C403Y|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVYRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >309|F480S|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRS AKRPAPVGV >310|L267V|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSVIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >311|V179F|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIFVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >312|A395D|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKDDLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >313|Q246P|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRPAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >314|Q254P|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACPKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >315|G43C|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGCTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >316|E223K|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAKKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >317|I338S|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADISITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >318|T392A|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWALKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >319|G385D|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVDYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >320|T342K|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITAKGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >321|D58A|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSAMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >322|P51L|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYLGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >323|D56A|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSASDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >324|Y84D|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEDVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >325|T186K|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGAKAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >326|R463S|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLSDIRLIRRGKIDDEGLRF AKRPAPVGV >327|G413D|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNDFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >328|A381P|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMPYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >329|G43S|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGSTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >330|L56V|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDVLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >331|R49W|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTWISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >332|R49P|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTPISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >333|I43A|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRADPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >334|I43S|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRSDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >335|I43T|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRTDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >336|T20P|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPPPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >337|A420V|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALVAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >338|E153G|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFGVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >339|E153A|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFAVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >340|S150C|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMCKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >341|E40Q|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPQTRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >342|S150G|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMGKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >343|R91W|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHWRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >344|E40G|ARO:3004157|Mycobacterium tuberculosis folC with mutation conferring resistance to para-aminosalicylic acid|MEG_2933|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|FOLC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPGTRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVAR MVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAF AAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQ LDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDS VVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART LFGRDPQ >345|N51T|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLTCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >346|I55S|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVSGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >347|D67H|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVHIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >348|E92A|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLAPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >349|S70R|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGRGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >350|G71V|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSVAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >351|Q127P|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDPLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >352|A138E|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSREVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >353|A183T|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGTVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >354|L79F|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPFA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >355|G117E|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRERAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >356|R47Q|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDQHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >357|W45C|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLCDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >358|L49F|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHFLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >359|G164C|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKCERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >360|P84C|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARCDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >361|V188M|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRMVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >362|A134E|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAEVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >363|P75S|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLSGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >364|V124G|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWGQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >365|A183E|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGEVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >366|V188G|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRGVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >367|G37V|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVVPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >368|A200E|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPETVVFARRGKQIARGSARMASGGTA >369|V139A|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAAAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >370|P84L|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARLDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >371|G30R|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPRVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >372|H48Y|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRYLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >373|L79S|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPSA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >374|W148R|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKRSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >375|W45S|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLSDRHLLNCAVIGELLERGDRVVDIGSGAGLPGVPLA IARPDLQVVLLEPLLRRTEFLREMVTDLGVAVEIVRGRAEESWVQDQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRML AIKGERAHDEVREHRRVMIASGAVDVRVVTCGANYLRPPATVVFARRGKQIARGSARMASGGTA >376|D94N|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYNSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >377|P102H|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYDSLVRMAQHWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >378|T80A|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAEA MGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >379|D94T|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYTSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >380|A74S|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSSRSVAET MGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >381|D94V|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYVSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >382|D94G|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYGSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >383|D89V|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGVASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >384|D94A|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYASLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >385|D89N|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGNASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >386|D89G|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGGASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >387|G88C|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHCDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >388|D94Y|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYYSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >389|G88A|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHADASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >390|A90V|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDVSIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >391|A90G|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDGSIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >392|S91P|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDAPIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >393|N538D|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKDTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >394|N510D|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGDDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >395|E540V|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTVVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >396|N538K|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKKTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >397|E540D|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTDVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >398|T539P|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNPEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >399|V340L|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESLHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >400|D500H|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGHSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >401|T539N|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNNEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >402|S94A|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >403|I16T|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGITTDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >404|I194T|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPTRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >405|I47T|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLTQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >406|I21T|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSTAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >407|I95P|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSPGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >408|G141E|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPEGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >409|I21V|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSVAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >410|V78A|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRATE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >411|P3A|ARO:3003448|Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol|MEG_3430|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVAAGLCAYRDLRRKRARKWGDTVTQPDDPRRVGVIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLK QGKSQLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPDGTTAAVDIPVDDISTDVRRAPHAGGREVLRVEV GAPSPLLRGGLAFIDTPGVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPVGAVVATKTDLYPR WREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLNDKELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQL AVSLGSELSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVDHDLRTRFRTVTEDAERQIDSCDP TAHWAEIGNDVENAIATAVGDNFVWAYQRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPLRRG HKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKEDKQNRLLRVRSEAKANVRRFVDDISFVVSKQSR DRLKMIQRLLRDHYREIAEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGLEPTLTPRASLGRA >412|S501W|ARO:3003448|Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol|MEG_3430|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRRVGVIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLK QGKSQLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPDGTTAAVDIPVDDISTDVRRAPHAGGREVLRVEV GAPSPLLRGGLAFIDTPGVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPVGAVVATKTDLYPR WREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLNDKELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQL AVSLGSELSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVDHDLRTRFRTVTEDAERQIDSCDP TAHWAEIGNDVENAIATAVGDNFVWAYQRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPLRRG HKMIIGMRGSYGGVVMIGMLWSVVGLGLFNPLSVGAGLILGRMAYKEDKQNRLLRVRSEAKANVRRFVDDISFVVSKQSR DRLKMIQRLLRDHYREIAEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGLEPTLTPRASLGRA >413|G308R|ARO:3003448|Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol|MEG_3430|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRRVGVIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLK QGKSQLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPDGTTAAVDIPVDDISTDVRRAPHAGGREVLRVEV GAPSPLLRGGLAFIDTPGVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPVGAVVATKTDLYPR WREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLNDKELNEESNFPAIVKFLSEQVLSRATERVRARVLGEIRSATEQL AVSLGSELSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVDHDLRTRFRTVTEDAERQIDSCDP TAHWAEIGNDVENAIATAVGDNFVWAYQRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPLRRG HKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKEDKQNRLLRVRSEAKANVRRFVDDISFVVSKQSR DRLKMIQRLLRDHYREIAEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGLEPTLTPRASLGRA >414|R537H|ARO:3003448|Mycobacterium tuberculosis iniA mutant conferring resistance to Ethambutol|MEG_3430|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRRVGVIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLK QGKSQLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPDGTTAAVDIPVDDISTDVRRAPHAGGREVLRVEV GAPSPLLRGGLAFIDTPGVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPVGAVVATKTDLYPR WREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLNDKELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQL AVSLGSELSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVDHDLRTRFRTVTEDAERQIDSCDP TAHWAEIGNDVENAIATAVGDNFVWAYQRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPLRRG HKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKEDKQNRLLRVHSEAKANVRRFVDDISFVVSKQSR DRLKMIQRLLRDHYREIAEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGLEPTLTPRASLGRA >415|A47T|ARO:3004135|Mycobacterium tuberculosis iniB with mutation conferring resistance to ethambutol|MEG_3431|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTSLIDYILSLFRSEDAARSFVAAPGRAMTSAGLIDIAPHQISSVATNVVPGLNLGAGDPMSGLRQAVAARHGFAQDVAN VGFAGDAGAGVASVITTDVGAGLASGLGAGFLGQGGLALAASSGGFGGQVGLAAQVGLGFTAVIEAEVGAQVGAGLGIGT GLGAQAGMGFGGGVGLGLGGQAGGVIGGSAAGAIGAGVGGRLGGNGQIGVAGQGAVGAGVGAGVGGQAGIASQIGVSAGG GLGGVGNVSGLTGVSSNAVLASNASGQAGLIASEGAALNGAAMPHLSGPLAGVGVGGQAGAAGGAGLGFGAVGHPTPQPA ALGAAGVVAKTEAAAGVVGGVGGATAAGVGGAHGDILGHEGAALGSVDTVNAGVTPVEHGLVLPSGPLIHGGTGGYGGMN PPVTDAPAPQVPARAQPMTTAAEHTPAVTQPQHTPVEPPVHDKPPSHSVFDVGHEPPVTHTPPAPIELPSYGLFGLPGF >416|W83G|ARO:3003451|Mycobacterium tuberculosis iniC mutant conferring resistance to ethambutol|MEG_3432|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALAGTLKAGKSTLVNALVGDDIAPTDATEATRI VTGFRHGPTPRVTANHRGGRRANVPITRRGGLSFDLRRINPAELIDLEVEWPAEELIDATIVDTPGTSSLACDASERTLR LLVPADGVPRVDAVVFLLRTLNAADVALLKQIGGLVGGSVGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQM GICQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRRDSPLPVDAGIRAQLLERFGMFGIRMSIA VLAAGVTDSTGLAAELLERSGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADIDPLLADTHAFEE LRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGLDPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVR SAEAMVAEFSARR >417|P248A|ARO:3003451|Mycobacterium tuberculosis iniC mutant conferring resistance to ethambutol|MEG_3432|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALAGTLKAGKSTLVNALVGDDIAPTDATEATRI VTWFRHGPTPRVTANHRGGRRANVPITRRGGLSFDLRRINPAELIDLEVEWPAEELIDATIVDTPGTSSLACDASERTLR LLVPADGVPRVDAVVFLLRTLNAADVALLKQIGGLVGGSVGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQM GICQAVVAVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRRDSPLPVDAGIRAQLLERFGMFGIRMSIA VLAAGVTDSTGLAAELLERSGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADIDPLLADTHAFEE LRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGLDPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVR SAEAMVAEFSARR >418|C117D|ARO:3003784|Mycobacterium tuberculosis intrinsic murA conferring resistance to fosfomycin|MEG_4096|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITAPDEP KYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLE FPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLHPTEHRVIGDRIVAATWG IAAAMTRGDISVAGVDPAHLQLVLHKLHDAGATVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGT SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYP LFVENLVSLGAEIERVCC >419|R121K|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAEKIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNN SFGFGGHNVALAFGRY >420|G387D|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVADEPRYGDYRYAVNN SFGFGGHNVALAFGRY >421|D66N|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKNPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNN SFGFGGHNVALAFGRY >422|F413L|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNN SFGFGGHNVALALGRY >423|G269S|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGASITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNN SFGFGGHNVALAFGRY >424|G312S|ARO:3003463|Mycobacterium tuberculosis kasA mutant conferring resistance to isoniazid|MEG_3445|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KASA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRM SYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGA RAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHSTATPIGDA AEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNN SFGFGGHNVALAFGRY >425|R418L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHLDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >426|W328F|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKFDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >427|W321F|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV FTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >428|T275V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKVHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >429|M255Y|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRYAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >430|M255I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRIAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >431|M255C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRCAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >432|W107F|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAFHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >433|V473N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLNSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >434|V473G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLGSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >435|V473Y|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLYSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >436|V473W|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLWSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >437|V473F|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLFSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >438|V473S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLSSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >439|V473M|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLMSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >440|V473R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLRSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >441|V473K|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLKSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >442|V473I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLISTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >443|V473D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLDSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >444|L472I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQIVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >445|L472Q|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQQVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >446|L472K|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQKVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >447|Q471H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSHLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >448|Q471Y|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSYLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >449|L436G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTGLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >450|T435R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQRLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >451|L430V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPVVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >452|L427I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYIGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >453|D311S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKSAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >454|D311N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKNAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >455|S303C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSCYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >456|S303L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSLYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >457|S315I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITIGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >458|M126I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGIQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >459|S315N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITNGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >460|A234G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLAPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >461|V68G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEGATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >462|P131Q|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAQLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >463|R128Q|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQQFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >464|L101P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPPFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >465|R463L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQILASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >466|W91R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWRPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >467|P131R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFARLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >468|A350S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGSWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >469|Y337C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILCGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >470|W328G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKGDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >471|T275P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKPHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >472|T262R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVERAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >473|W300G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGGKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >474|Y229F|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIFVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >475|N138S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDSASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >476|N138D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDDASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >477|H108Q|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWQAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >478|H108E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWEAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >479|W107R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMARHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >480|R104L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFILMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >481|G33V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGVGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >482|G111S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAASTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >483|H417Q|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIQRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >484|E607A|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAAYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >485|Q461P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSPIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >486|G125S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGSMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >487|N508D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVDDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >488|L147P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRPLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >489|N660D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVDLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >490|A312P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDPITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >491|S383P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLPLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >492|H97R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGRYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >493|R489S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKSGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >494|M420T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDTGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >495|D387H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVHPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >496|G123E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAEGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >497|G299S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLSWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >498|D419H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRHMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >499|M176T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESTGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >500|R632C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLCVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >501|D542H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFAHLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >502|Y64S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDSAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >503|Y95C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADCGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >504|P131T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFATLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >505|A139P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNPSLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >506|D142G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLGKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >507|A162V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WVDLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >508|G269D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGDHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >509|T306P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGPGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >510|R385W|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLWVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >511|D387G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVGPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >512|T394M|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERIMRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >513|Q439P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWPDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >514|F483L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSLRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >515|A541D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFDDLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >516|G32D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEDGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >517|V47E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKELHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >518|D194G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPGEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >519|A256T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMTMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >520|T667P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGIPWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >521|M624V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEVTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >522|A716P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDPQPKF VQDFVAAWDKVMNLDRFDVR >523|I335T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLETLYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >524|Q127P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMPRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >525|Q352E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWEYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >526|Y98C|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHCGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >527|A379T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLTTDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >528|G269R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGRHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >529|A431V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEAPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >530|D194Y|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPYEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >531|S17T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAATNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >532|A93T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPTDYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >533|D37E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQEWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >534|A110V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAVGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >535|A139V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNVSLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >536|G299W|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLWWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >537|H276M|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTMGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >538|Q295H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEHMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >539|S17N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAANNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >540|G19D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNDCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >541|Q224E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVEMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >542|A243S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMSAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >543|A550D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCDAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >544|P2S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >545|S140N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNANLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >546|G279D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGADPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >547|G285D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVDPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >548|G316D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSDIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >549|S457I|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIAILKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >550|G593D|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADDFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >551|D63E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFEYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >552|N133T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLTSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >553|P232S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNSEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >554|Q127E|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMERFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >555|D735N|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLNRFDVR >556|G629S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVSGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >557|L587M|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVMEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >558|S315T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >559|S315R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITRGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >560|S315G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITGGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >561|A264V|ARO:3005102|Mycobacterium tuberculosis katG mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAVLIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >562|G490S|ARO:3005102|Mycobacterium tuberculosis katG mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRSGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >563|F355S|ARO:3005108|Mycobacterium tuberculosis mshA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALLAVHTSPLAQPGTGDAGGMNVYMLQSALHLA RRGIEVEIFTRATASADPPVVRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDIVHSHYWLSGQ VGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRTVGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHP GVDLDVFRPGDRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPGVRIIVAGGPSGSGLASPDGLVRLADELG ISARVTFLPPQSHTDLATLFRAADLVAVPSYSESSGLVAVEAQACGTPVVAAAVGGLPVAVRDGITGTLVSGHEVGQWAD AIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDALLASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA >564|H285Y|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWYFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >565|R738Q|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGQSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >566|V287F|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFFGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >567|G288W|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVWANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >568|G288V|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVVANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >569|Y296H|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGHILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >570|Y296S|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGSILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >571|I297L|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYLLTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >572|I297T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYTLTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >573|M300R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTRARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >574|R302G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMAGVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >575|V303G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARGSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >576|S244T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGATLVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >577|V981L|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPLFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >578|T270I|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >579|P398S|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRSEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >580|Q491R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDRTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >581|L502P|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLPKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >582|G308D|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHADYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >583|N394D|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDDGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >584|Y309N|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGNMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >585|M310K|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYKANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >586|Y327N|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWNYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >587|W326R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGRYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >588|A247P|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVPLHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >589|L251R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHIRDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >590|G325S|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFSWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >591|A254G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTGDGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >592|A307T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHTGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >593|L50V|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHVFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >594|G339A|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQAAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >595|V18A|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVAIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >596|G313R|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPRYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >597|A300P|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRPGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >598|R268H|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRHIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >599|T110A|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQAPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >600|R13C|ARO:3003461|Mycobacterium tuberculosis ndh with mutation conferring resistance to isoniazid|MEG_4130|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPCRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >601|D8Y|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVYVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >602|Q10K|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVKNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >603|T47S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVASKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >604|D49V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKVFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >605|S66P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSPSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >606|K96E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYEGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >607|A102T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGTYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >608|A102V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGVYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >609|L116R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPRLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >610|V125D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGDDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >611|I133T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGTATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >612|Q141P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRPTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >613|R154G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATGVLVDLT AGVSADTTVAALEEMRTASVELVCSS >614|T160P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLP AGVSADTTVAALEEMRTASVELVCSS >615|A161P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT PGVSADTTVAALEEMRTASVELVCSS >616|D12A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNAFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >617|D12N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNNFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >618|H51Q|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFQIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >619|A171P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAPLEEMRTASVELVCSS >620|H57D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDDFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >621|W68L|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSLPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >622|V139A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCARQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >623|R121P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLPQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >624|H137R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDRCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >625|W119R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNRLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >626|F94P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVPYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >627|T76P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGPPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >628|L19P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSPAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >629|S104C|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYCGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >630|I90S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSASEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >631|M1S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE SRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >632|L4W|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRAWIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >633|V7D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIDDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >634|V7F|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIFDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >635|A8G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVGVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >636|V9G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDGQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >637|C14R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFREGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >638|C14Y|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFYEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >639|G23V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTVGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >640|V45G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVGATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >641|A46E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVETKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >642|D49A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKAFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >643|F58L|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHLSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >644|Y68D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSDPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >645|S67P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSPWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >646|W68R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSRPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >647|W68G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSGPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >648|W68S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSSPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >649|T76I|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGIPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >650|G78D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPDAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >651|L85R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSRDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >652|K96Q|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYQGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >653|Y103H|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAHSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >654|Y103S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGASSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >655|T135P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIAPDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >656|D136N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATNHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >657|D136Y|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATYHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >658|V139M|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCMRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >659|A146T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDTVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >660|V155G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRGLVDLT AGVSADTTVAALEEMRTASVELVCSS >661|L159R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDRT AGVSADTTVAALEEMRTASVELVCSS >662|L172P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAAPEEMRTASVELVCSS >663|V180F|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASFELVCSS >664|L172A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAAAEEMRTASVELVCSS >665|A171T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVATLEEMRTASVELVCSS >666|H51Y|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFYIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >667|P62H|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTHDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >668|A171V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAVLEEMRTASVELVCSS >669|D136H|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATHHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >670|A3E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRELIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >671|L27P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAAPARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >672|P54L|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDLGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >673|C72W|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHWVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >674|M175V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEVRTASVELVCSS >675|H59D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFDGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >676|A46V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVVTKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >677|D53A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIAPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >678|H71E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPECVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >679|H82R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FRPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >680|G97S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKSAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >681|A134V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIVTDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >682|C138S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHSVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >683|T168N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTNVAALEEMRTASVELVCSS >684|T47P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVAPKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >685|Y34S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDSLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >686|G17D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGDSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >687|P54T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDTGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >688|A140S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVSQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >689|T47A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVAAKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >690|D12E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNEFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >691|W68C|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSCPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >692|T142M|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQMAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >693|T142K|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQKAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >694|V139L|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCLRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >695|C138Y|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHYVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >696|H137P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDPCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >697|G132S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVSIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >698|N118T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLTWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >699|K96N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYNGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >700|L85P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSPDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >701|C72R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHRVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >702|P69R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWRPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >703|Y41H|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADHHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >704|A26G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAGLARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >705|Q10P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVPNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >706|Q10R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVRNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >707|V7G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIGDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >708|I5S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALSIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >709|L182S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVESVCSS >710|E174G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEGMRTASVELVCSS >711|L72P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHPVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >712|A161G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT GGVSADTTVAALEEMRTASVELVCSS >713|V157G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLGDLT AGVSADTTVAALEEMRTASVELVCSS >714|R157W|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLWDLT AGVSADTTVAALEEMRTASVELVCSS >715|T100P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYPGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >716|R140G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVGQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >717|C138W|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHWVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >718|K96M|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYMGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >719|S164P|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVPADTTVAALEEMRTASVELVCSS >720|H57Q|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDQFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >721|G17S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGSSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >722|V9A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDAQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >723|G8R|ARO:3004184|Mycobacterium tuberculosis ribD with mutation conferring resistance to para-aminosalicylic acid|MEG_6055|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|RIBD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPDSGQLRAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADV IVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLA EVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRC AHVLTDDSGYLYTRYVKT >724|S531L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEELRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >725|N518T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVTSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >726|S522Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEQVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >727|K527N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTNDEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >728|R528H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTAHEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >729|S512R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRRVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >730|L521M|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDMIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >731|H526G|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLGADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >732|F505L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGLIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >733|S574L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMLVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >734|G507S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFISTPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >735|G507D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIDTPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >736|T508P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIEPPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >737|T508A|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIEAPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >738|T508H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIEHPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >739|Q513D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKDVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >740|Q513E|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKEVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >741|S456W|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGWLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >742|D515H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVHGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >743|N519K|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVKDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >744|G523A|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIAYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >745|H526F|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLFADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >746|H526Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLQADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >747|S531F|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEFRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >748|S531C|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEECRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >749|S512T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRTVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >750|L511R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLHADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >751|S512I|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRIVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >752|H526N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLNADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >753|R529Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADQEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >754|H526T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYLKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >755|R528P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTAPEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >756|L525S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYSTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >757|Q517L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGLVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >758|S509Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETQYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >759|S509R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETRYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >760|E672D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARDNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >761|H526E|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLEADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >762|L511V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYVKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >763|L533P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRPVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >764|T508N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIENPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >765|S512N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRNVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >766|P520T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSTEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >767|S531W|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEWRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >768|S531G|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEGRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >769|H526D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLDADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >770|H526S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLSADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >771|K527Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTQDEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >772|D515T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVTGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >773|D515Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVYGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >774|M515I|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVIGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >775|M515V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVVGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >776|L511P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYPKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >777|I572F|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDFMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >778|S522L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDELVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >779|H526Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLYADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >780|L538R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQRNSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >781|V176F|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRFPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >782|Q438K|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNKPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >783|L533R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRRVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >784|D441V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLVGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >785|D441Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLYGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >786|S447Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKQRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >787|H451Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSYLGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >788|H451C|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSCLGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >789|H451D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSDLGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >790|H451R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSRLGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >791|S456L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGLLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >792|H526C|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLCADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >793|S450L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLLALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >794|H526L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLLADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >795|D515G|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVGGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >796|D515N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVNGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >797|Q513K|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKKVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >798|Q513L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKLVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >799|V146F|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTFFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >800|A381V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQVQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >801|L521P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDPIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >802|H526R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLRADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >803|S522W|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEWVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >804|Q513P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKPVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >805|Q490H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGHIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >806|E504A|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFAFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >807|D518H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVHSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >808|Q513R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKRVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >809|H526P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLPADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >810|Q517H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGHVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >811|T508S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIESPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >812|L511M|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYMKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >813|D515K|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVKGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >814|N518I|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVISDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >815|L538P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQPNSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >816|L545M|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDAMGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >817|L571V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVVYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >818|R633C|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDACDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >819|D342N|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGNDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >820|D343N|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDNAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >821|A344P|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDPMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >822|I351F|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDAMVKVIDFDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >823|E325K|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISKLAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >824|G341R|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVRDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >825|D123A|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKAEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >826|S324F|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHIFELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >827|K88R|ARO:3003395|Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin|MEG_6144|Drugs|Aminoglycosides|Aminoglycoside-resistant_16S_ribosomal_subunit_protein|RPSL|RequiresSNPConfirmation|Campylobacter|WP_057042458.1|88|rpsL_K88R|AMINOGLYCOSIDE|STREPTOMYCIN|Campylobacter_streptomycin_resistant_RpsL|wt_coherence=TRUE MPTIQQLVRKGRRDKISKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMV LVRGGRVRDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKG >828|K43R|ARO:3003395|Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin|MEG_6144|Drugs|Aminoglycosides|Aminoglycoside-resistant_16S_ribosomal_subunit_protein|RPSL|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPTIQQLVRKGRRDKISKVKTAALKGSPQRRGVCTRVYTTTPRKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMV LVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKG >829|T40I|ARO:3003395|Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin|MEG_6144|Drugs|Aminoglycosides|Aminoglycoside-resistant_16S_ribosomal_subunit_protein|RPSL|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPTIQQLVRKGRRDKISKVKTAALKGSPQRRGVCTRVYTITPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMV LVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKG >830|K88Q|ARO:3003395|Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin|MEG_6144|Drugs|Aminoglycosides|Aminoglycoside-resistant_16S_ribosomal_subunit_protein|RPSL|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPTIQQLVRKGRRDKISKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMV LVRGGRVQDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKG >831|G91R|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELRPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >832|T202A|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWAGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >833|Y36C|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRCDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >834|V77F|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGFTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >835|W83C|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DECASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >836|S105P|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPPGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >837|R126Q|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSQRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >838|F152V|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQVYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >839|C161T|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS TQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >840|H207R|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCRIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >841|I211V|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDVHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >842|P224L|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSRELRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >843|R235P|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADPDSIFE YTYEDIVVKNYDPHPAIKAPVAV >844|T22A|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRAGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >845|H75N|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHENGVTIW DEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >846|W101R|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQWRSRPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLS CQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE YTYEDIVVKNYDPHPAIKAPVAV >847|F185L|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQLEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >848|E238K|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVKYF LWLRTQTDRALSAKGLEDAVHRAISEGP >849|V128E|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPREVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >850|A67E|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGEHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >851|L150P|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDPVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >852|A91E|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGESTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >853|L118P|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQPAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >854|P183L|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKLQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >855|K69E|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHELVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >856|R14W|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRWGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >857|N236K|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGKVEYF LWLRTQTDRALSAKGLEDAVHRAISEGP >858|Q998R|ARO:3003325|Mycobacterium tuberculosis variant bovis embB with mutation conferring resistance to ethambutol|MEG_2711|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPSRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQRPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >859|T610K|ARO:3003325|Mycobacterium tuberculosis variant bovis embB with mutation conferring resistance to ethambutol|MEG_2711|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPSRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALKTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >860|F1012S|ARO:3003325|Mycobacterium tuberculosis variant bovis embB with mutation conferring resistance to ethambutol|MEG_2711|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPSRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKSRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >861|R202W|ARO:3003779|Mycobacterium tuberculosis variant bovis ndh with mutation conferring resistance to isoniazid|MEG_4131|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFWHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPRYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >862|V329A|ARO:3003779|Mycobacterium tuberculosis variant bovis ndh with mutation conferring resistance to isoniazid|MEG_4131|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPRYPNVFVV GDMAAVEGAPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >863|L239P|ARO:3003779|Mycobacterium tuberculosis variant bovis ndh with mutation conferring resistance to isoniazid|MEG_4131|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKPG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPRYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >864|D366G|ARO:3003779|Mycobacterium tuberculosis variant bovis ndh with mutation conferring resistance to isoniazid|MEG_4131|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQR NVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAER SSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLG VEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPRYPNVFVV GDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFGKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLH LAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS >865|A91T|ARO:3003298|Mycobacterium leprae gyrA conferring resistance to fluoroquinolones|MEG_3181|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDITLPPGDGSIQRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMLDSGFRPDRSHAKSARSVAE TMGNYHPHGDTSIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYCVSGNSLVRLLFGKSIRIGDIVTGAQFNSD NPIDLKVLDRHGNPVVADYLFHSGEHQTYTVRTTEGYEITGTSNHPLLCLVNVGGIPTLLWKLIGEIRSGDYVVLQRIPP VEFGPADWYSTMEALLFGAFISGGFVFQDHAGFNSLDRDYFTMVVNAYDTVVGGLRCISSRITVSGSTLLELDVYNLIEF KKTRLSGLCGQRSADKLVPDWLWHSPSTVKRAFLQALFEGEGFSSILSRNIIEISYSTLSERLAADVQQMLLEFGVVSER YCHTVNEYKVVIANRAQVEMFFTQVGFGVTKQAKLIRDVVSMSPCVGMDINCVPGLATFIRKHCDNRWVEEDSFNQHNVD CVQHWHHHSAEIVGHIADPDIRAIVTDLTDGRFYYARVASVTDTGIQPVFSLHVDTEDHSFLTNGFISHNTEARLTPLAM EMLREIDEETVDFISNYDGRVQEPMVLPSRFPNLLANGSGGIAVGMATNIPPHNLYELADAVFWCLENHDADEETMLVAV MERVKGPDFPTAGLIVGSQGIADAYKTGRGSIRIRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRTGRLAGI SNVEDQGSDRVGVRIVIEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMICYYVEHQLDVIVRRTTY RLRKANERAHILRGLVKALDALDEVITLIRASQTVDIARVGVVELLDIDDIQAQAILDMQLRRLAALERQRIIDDLAKIE VEIADLGDILAKPERRRGIIRNELTEIAEKYGDDRRTRIIAVDGDVNDEDLIAREEVVVTITETGYAKRTKTDLYRSQKR GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIAQVIQIRSYED APYLVLATRAGLVKKSKLTDFDSNRSGGIVAINLRDNDELVGAVLCAADGDLLLVSANGQSIRFSATDEALRPMGRATSG VQGMRFNADDRLLSLNVVREDTYLLVATSGGYAKRTSIEEYPMQGRGGKGVLTVMYDRRRGSLVGAIVVDEDSELYAITS GGGVIRTTARQVRQAGRQTKGVRLMNLGEGDTLLAIARNAEESADGGVG >866|A115T|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIITAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >867|I17T|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVITGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >868|Y122N|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSNFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >869|R145C|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELCGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >870|F170S|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTSTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >871|A187P|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIPELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >872|V246A|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMATDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >873|V272E|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKEWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >874|V300G|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRGKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >875|Q335H|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIHGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >876|Y361H|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEHFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >877|T29P|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKPLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >878|H46P|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHPLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >879|G84D|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLDDVTHIDLENKTVDSVLLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >880|L100P|ARO:3003778|Mycolicibacterium smegmatis ndh with mutation conferring resistance to isoniazid|MEG_4132|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|NDH|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSHPGATASDRHKVVIIGSGFGGLTAAKTLKRADVDVKLIARTTHHLFQPLLYQVATGIISEGEIAPATRVILRKQKNAQ VLLCDVTHIDLENKTVDSVPLGHTYSTPYDSLIIAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILGAFEQAERSSD PVRRAKLLTFTVVGAGPTGVEMAGQIAELADQTLRGSFRHIDPTEARVILLDAAPAVLPPMGEKLGKKARARLEKMGVEV QLGAMVTDVDRNGITVKDSDGTIRRIESACKVWSAGVSASPLGKDLAEQSGVELDRAGRVKVQPDLTLPGHPNVFVVGDM AAVEGVPGVAQGAIQGGRYAAKIIKREVSGTSPKIRTPFEYFDKGSMATVSRFSAVAKVGPVEFAGFFAWLCWLVLHLVY LVGFKTKIVTLLSWGVTFLSTKRGQLTITEQQAYARTRIEELEEIAAAVQDTEKAAS >881|M95I|ARO:3004631|Mycoplasma genitalium gyrA mutation confers resistance to fluoroquinolones|MEG_3185|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKQQDQVDKIRENLDNSTVKSISLANELERSFMEYAMSVIVARALPDARDGLKPVHRRVLYGAYIGGMHHDRPFKKSAR IVGDVMSKFHPHGDIAIYDTMSRMAQDFSLRYLLIDGHGNFGSIDGDRPAAQRYTEARLSKLAAELLKDIDKDTVDFIAN YDGEEKEPTVLPAAFPNLLANGSSGIAVGMSTSIPSHNLSELIAGLIMLIDNPQCTFQELLTVIKGPDFPTGANIIYTKG IESYFETGKGNVVIRSKVEIEQLQTRSALVVTEIPYMVNKTTLIEKIVELVKAEEISGIADIRDESSREGIRLVIEVKRD TVPEVLLNQLFKSTRLQVRFPVNMLALVKGAPVLLNMKQALEVYLDHQIDVLVRKTKFVLNKQQERYHILSGLLIAALNI DEVVAIIKKSANNQEAINTLNTKFKLDEIQAKAVLDMRLRSLSVLEVNKLQTEQKELKDSIEFCKKVLADQKLQLKIIKE ELQKINDQFGDERRSEILYDISEEIDDESLIKVENVVITMSTNGYLKRIGVDAYNLQHRGGVGVKGLTTYVDDSISQLLV CSTHSDLLFFTDKGKVYRIRAHQIPYGFRTNKGIPAVNLIKIEKDERICSLLSVNNYDDGYFFFCTKNGIVKRTSLNEFI NILSNGKRAISFDDNDTLYSVIKTHGNDEIFIGSTNGFVVRFHENQLRVLSRTARGVFGISLNKGEFVNGLSTSSNGSLL LSVGQNGIGKLTSIDKYRLTKRNAKGVKTLRVTDRTGPVVTTTTVFGNEDLLMISSAGKIVRTSLQELSEQGKNTSGVKL IRLKDNERLERVTIFKEELEDKEMQLEDVGSKQITQ >882|G93C|ARO:3004631|Mycoplasma genitalium gyrA mutation confers resistance to fluoroquinolones|MEG_3185|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKQQDQVDKIRENLDNSTVKSISLANELERSFMEYAMSVIVARALPDARDGLKPVHRRVLYGAYIGGMHHDRPFKKSAR IVGDVMSKFHPHCDMAIYDTMSRMAQDFSLRYLLIDGHGNFGSIDGDRPAAQRYTEARLSKLAAELLKDIDKDTVDFIAN YDGEEKEPTVLPAAFPNLLANGSSGIAVGMSTSIPSHNLSELIAGLIMLIDNPQCTFQELLTVIKGPDFPTGANIIYTKG IESYFETGKGNVVIRSKVEIEQLQTRSALVVTEIPYMVNKTTLIEKIVELVKAEEISGIADIRDESSREGIRLVIEVKRD TVPEVLLNQLFKSTRLQVRFPVNMLALVKGAPVLLNMKQALEVYLDHQIDVLVRKTKFVLNKQQERYHILSGLLIAALNI DEVVAIIKKSANNQEAINTLNTKFKLDEIQAKAVLDMRLRSLSVLEVNKLQTEQKELKDSIEFCKKVLADQKLQLKIIKE ELQKINDQFGDERRSEILYDISEEIDDESLIKVENVVITMSTNGYLKRIGVDAYNLQHRGGVGVKGLTTYVDDSISQLLV CSTHSDLLFFTDKGKVYRIRAHQIPYGFRTNKGIPAVNLIKIEKDERICSLLSVNNYDDGYFFFCTKNGIVKRTSLNEFI NILSNGKRAISFDDNDTLYSVIKTHGNDEIFIGSTNGFVVRFHENQLRVLSRTARGVFGISLNKGEFVNGLSTSSNGSLL LSVGQNGIGKLTSIDKYRLTKRNAKGVKTLRVTDRTGPVVTTTTVFGNEDLLMISSAGKIVRTSLQELSEQGKNTSGVKL IRLKDNERLERVTIFKEELEDKEMQLEDVGSKQITQ >883|V103I|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYDAIIRMSQSWKNNWTTISIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >884|D87N|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYNAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >885|D87H|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYHAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >886|A67S|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSSRAVGEIMGKYHPH GDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >887|P62S|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTSYKKSARAVGEIMGKYHPH GDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >888|D87Y|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYYAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >889|D87G|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYGAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >890|S83N|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDNSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >891|A119V|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAVMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >892|A67T|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSTRAVGEIMGKYHPH GDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >893|G81C|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH CDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >894|D82N|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GNSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >895|S83R|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDRSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >896|S83I|ARO:3004630|Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin|MEG_5331|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPH GDISIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLP TLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKF IIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHT QLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKS DAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRR SQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIP VYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVS AFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVV SRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN >897|S91I|ARO:3003310|Mycoplasma hominis parC conferring resistance to fluoroquinolones|MEG_5330|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKDRKEEIQEVTENIIEKNMADIMSDRFGRYSKYIIQQRAIPDARDGLKPVQRRILYSMWNLHLKNSEPFKKSARIVGD VIGRYHPHGDISIYEALVRMAQDWKSNFPLIEMHGNKGSIDDDPAAAMRYTESRLEKISELMLRDLDRKVVKMAPNFDDS EYEPIVLPALFPNLLVNGAKGIAAGFATEIPPHNLGEVIDATIALIKNPTISIEELSEIVKGPDFPTGAIINGINEIKKA LSSGQGRITISSKYHYVYDKKDESKIIGIEIIEIPFGVVKSKLVADIDAIAIDKKISGIKEVLDQTDRNGISIFIQLEDG ANADAIIAYLMNKTELSISYSYNMVAIDNNRPVILNLYSALIAYLSHLKEVNINGINYDLKKFKLRLEIVEGFIKVAEIS DEVIHLIKESDNSKKGVILALMNKFKFSELQATAIAELRLYKLSRMDQIEFQEEKKNLEIQIENCNKLLNDKWEFNQYLI KQLLEIKNQYSKPRLTEISDQKIDKEIDHKLLTKNEDFYLYITKDGYYKKISLKVYTSNELNTFKLKEEDNVFYFDKVNS LSKILFFTNLGNYFIIDCHLFKDCNWKDLGQHISSIVALESSEKIIRVIEITSFNSYANFILMSKLGYAKKVNLRDFENK SSLKTKTCMSFKDDNDELIDAQISNDEKMLFILLNNGMYHLVSENELKVGISLKARGIRLLLNLYKHPQLQVSGFITVSK YNNIIYLTQGGYIKCWDTSKLELTTRNTPKMLFTPLKNNILGLQSLAVTLSNLKMLYTDNNGNLAEYDWKFILKDKTKES KLLKLDYSFTNPGYFITPIKINELIEADEIEQEKIRQEYQGYIDKNIELTAEHALIKKSYDQDIQHLNNEEQEELFQIST EDIELPNVSNNVNDNQKDKKNIATKESVSQKIQEIEKIDLETIMQKIKQIKKK >898|K149R|ARO:3003310|Mycoplasma hominis parC conferring resistance to fluoroquinolones|MEG_5330|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKDRKEEIQEVTENIIEKNMADIMSDRFGRYSKYIIQQRAIPDARDGLKPVQRRILYSMWNLHLKNSEPFKKSARIVGD VIGRYHPHGDSSIYEALVRMAQDWKSNFPLIEMHGNKGSIDDDPAAAMRYTESRLEKISELMLRDLDRRVVKMAPNFDDS EYEPIVLPALFPNLLVNGAKGIAAGFATEIPPHNLGEVIDATIALIKNPTISIEELSEIVKGPDFPTGAIINGINEIKKA LSSGQGRITISSKYHYVYDKKDESKIIGIEIIEIPFGVVKSKLVADIDAIAIDKKISGIKEVLDQTDRNGISIFIQLEDG ANADAIIAYLMNKTELSISYSYNMVAIDNNRPVILNLYSALIAYLSHLKEVNINGINYDLKKFKLRLEIVEGFIKVAEIS DEVIHLIKESDNSKKGVILALMNKFKFSELQATAIAELRLYKLSRMDQIEFQEEKKNLEIQIENCNKLLNDKWEFNQYLI KQLLEIKNQYSKPRLTEISDQKIDKEIDHKLLTKNEDFYLYITKDGYYKKISLKVYTSNELNTFKLKEEDNVFYFDKVNS LSKILFFTNLGNYFIIDCHLFKDCNWKDLGQHISSIVALESSEKIIRVIEITSFNSYANFILMSKLGYAKKVNLRDFENK SSLKTKTCMSFKDDNDELIDAQISNDEKMLFILLNNGMYHLVSENELKVGISLKARGIRLLLNLYKHPQLQVSGFITVSK YNNIIYLTQGGYIKCWDTSKLELTTRNTPKMLFTPLKNNILGLQSLAVTLSNLKMLYTDNNGNLAEYDWKFILKDKTKES KLLKLDYSFTNPGYFITPIKINELIEADEIEQEKIRQEYQGYIDKNIELTAEHALIKKSYDQDIQHLNNEEQEELFQIST EDIELPNVSNNVNDNQKDKKNIATKESVSQKIQEIEKIDLETIMQKIKQIKKK >899|R229S|ARO:3004873|Neisseria gonorrhoeae folP with mutation conferring resistance to sulfonamides|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARHVWRAGRFEIGLDKPKIMGIVNLTPDSFSDGGAYSQNAQTALAHAERLLKEGADILDIGGESTRPGADFVPPEEEEW ARVEPVLAEAAGWGVPVSLDTRRTVVMEKALALGGIDIINDVAALTDEGAVELLARQADTGICLMHMRGLPETMQDNPKY QDVVGEVARYLKTRSETCVAAGIAPQRITLDPGFGFGKNLQHNIALMRHLPELMAETGLPLLIGVSRKSMIGELTGEADA AARVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGVNR >900|D95G|ARO:3003928|Neisseria gonorrhoeae gyrA conferring resistance to fluoroquinolones|MEG_3177|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDATIRHDHKFALETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGD VIGKYHPHGDSAVYGTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGS EHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPKTEIDELIDIIQAPDFPTGATIYGLGGVREG YKTGRGRVVIRGKTHIEPIGKNGEREAIVIDEIPYQVNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNE NAEVVLNQLYKLTPLQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAEGKAVALSNID EIIKLIKESPNAAEAKEKLLARPWRSSLVEEMLTRSGLDLEMMRPEGLAANIGLKKQGYYLSEIQADAILRMSLRNLTGL DQKEIIESYKNLMGKIIDFVDILSKPERITQIIRDELEEIKTNYGDERRSEINPFGGDIADEDLIPQREMVVTLTHGGYI KTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGE KVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGIKAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEY WEKSGNDEAEDADIETEISDDLEDETADNENTLPSGKNGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEESGLQVLT ATANGYGKRTPIADYSRKNKGGQGSIAINTGERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLIN LDEGETLVSLERVAEDESELSGASVISNVTEPEAEN >901|S91F|ARO:3003928|Neisseria gonorrhoeae gyrA conferring resistance to fluoroquinolones|MEG_3177|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDATIRHDHKFALETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGD VIGKYHPHGDFAVYDTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGS EHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPKTEIDELIDIIQAPDFPTGATIYGLGGVREG YKTGRGRVVIRGKTHIEPIGKNGEREAIVIDEIPYQVNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNE NAEVVLNQLYKLTPLQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAEGKAVALSNID EIIKLIKESPNAAEAKEKLLARPWRSSLVEEMLTRSGLDLEMMRPEGLAANIGLKKQGYYLSEIQADAILRMSLRNLTGL DQKEIIESYKNLMGKIIDFVDILSKPERITQIIRDELEEIKTNYGDERRSEINPFGGDIADEDLIPQREMVVTLTHGGYI KTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGE KVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGIKAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEY WEKSGNDEAEDADIETEISDDLEDETADNENTLPSGKNGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEESGLQVLT ATANGYGKRTPIADYSRKNKGGQGSIAINTGERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLIN LDEGETLVSLERVAEDESELSGASVISNVTEPEAEN >902|D95N|ARO:3003928|Neisseria gonorrhoeae gyrA conferring resistance to fluoroquinolones|MEG_3177|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDATIRHDHKFALETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGD VIGKYHPHGDSAVYNTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGS EHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPKTEIDELIDIIQAPDFPTGATIYGLGGVREG YKTGRGRVVIRGKTHIEPIGKNGEREAIVIDEIPYQVNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNE NAEVVLNQLYKLTPLQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAEGKAVALSNID EIIKLIKESPNAAEAKEKLLARPWRSSLVEEMLTRSGLDLEMMRPEGLAANIGLKKQGYYLSEIQADAILRMSLRNLTGL DQKEIIESYKNLMGKIIDFVDILSKPERITQIIRDELEEIKTNYGDERRSEINPFGGDIADEDLIPQREMVVTLTHGGYI KTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGE KVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGIKAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEY WEKSGNDEAEDADIETEISDDLEDETADNENTLPSGKNGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEESGLQVLT ATANGYGKRTPIADYSRKNKGGQGSIAINTGERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLIN LDEGETLVSLERVAEDESELSGASVISNVTEPEAEN >903|K450T|ARO:3004859|Neisseria gonorrhoeae gyrB conferring resistance to zoliflodacin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMVFEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGR GMPTGIHPKEGRSAAEVIMTVLHAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKI VGDSDKKGTTVRFLAGTETFGNIEYSFDILAKRIRELSFLNNGVDIELTDERDGKHESFALSGGVAGFVQYMNRKKTPLH EKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNIPQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMRE GLTCVLSVKLPDPKFSSQTKDKLVSGEIGPVVNEVINQALTDFLEENPNEAKIITGKIVDAARAREAARKAREIPRRKGV MDGLGLPGKLADCQEKDPALSELYLVEGDSAGGSAMQGRDRKFQAILPLTGKILNVEKARFEKMLASQEVATLITALGAG IGKEEFNPEKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLL GLALEKAKIVSDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENADKAVAELSGLLDEKEA ALERIEGHEGHQFIKITRKLHGNVMVSYIEPKFLNSKAYQTLTQTAAALKGLVGEGAKLYKGENEYDADSFETALDILMS VAQKGMSIQRYKGLGEMNPEQLWETTMDPTVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA >904|K450N|ARO:3004859|Neisseria gonorrhoeae gyrB conferring resistance to zoliflodacin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMVFEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGR GMPTGIHPKEGRSAAEVIMTVLHAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKI VGDSDKKGTTVRFLAGTETFGNIEYSFDILAKRIRELSFLNNGVDIELTDERDGKHESFALSGGVAGFVQYMNRKKTPLH EKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNIPQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMRE GLTCVLSVKLPDPKFSSQTKDKLVSGEIGPVVNEVINQALTDFLEENPNEAKIITGKIVDAARAREAARKAREIPRRKGV MDGLGLPGKLADCQEKDPALSELYLVEGDSAGGSAMQGRDRKFQAILPLNGKILNVEKARFEKMLASQEVATLITALGAG IGKEEFNPEKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLL GLALEKAKIVSDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENADKAVAELSGLLDEKEA ALERIEGHEGHQFIKITRKLHGNVMVSYIEPKFLNSKAYQTLTQTAAALKGLVGEGAKLYKGENEYDADSFETALDILMS VAQKGMSIQRYKGLGEMNPEQLWETTMDPTVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA >905|D429N|ARO:3004859|Neisseria gonorrhoeae gyrB conferring resistance to zoliflodacin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMVFEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGR GMPTGIHPKEGRSAAEVIMTVLHAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKI VGDSDKKGTTVRFLAGTETFGNIEYSFDILAKRIRELSFLNNGVDIELTDERDGKHESFALSGGVAGFVQYMNRKKTPLH EKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNIPQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMRE GLTCVLSVKLPDPKFSSQTKDKLVSGEIGPVVNEVINQALTDFLEENPNEAKIITGKIVDAARAREAARKAREIPRRKGV MDGLGLPGKLADCQEKDPALSELYLVEGNSAGGSAMQGRDRKFQAILPLKGKILNVEKARFEKMLASQEVATLITALGAG IGKEEFNPEKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLL GLALEKAKIVSDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENADKAVAELSGLLDEKEA ALERIEGHEGHQFIKITRKLHGNVMVSYIEPKFLNSKAYQTLTQTAAALKGLVGEGAKLYKGENEYDADSFETALDILMS VAQKGMSIQRYKGLGEMNPEQLWETTMDPTVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA >906|A121D|ARO:3000464|Neisseria gonorrhoeae porin PIB (por)|MEG_5808|Drugs|Multi-drug_resistance|MDR_mutant_porin_proteins|POR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTKGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQ GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTGDNVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG FSGSVQYAPKDNSGSNGESYHVGLNYRNNGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNAL YVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSAL VSAGWLQEGKGADKIVSTASAVVLRHKF >907|G120K|ARO:3000464|Neisseria gonorrhoeae porin PIB (por)|MEG_5808|Drugs|Multi-drug_resistance|MDR_mutant_porin_proteins|POR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTKGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQ GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTKANVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG FSGSVQYAPKDNSGSNGESYHVGLNYRNNGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNAL YVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSAL VSAGWLQEGKGADKIVSTASAVVLRHKF >908|G120D|ARO:3000464|Neisseria gonorrhoeae porin PIB (por)|MEG_5808|Drugs|Multi-drug_resistance|MDR_mutant_porin_proteins|POR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTKGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQ GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTDANVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG FSGSVQYAPKDNSGSNGESYHVGLNYRNNGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNAL YVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSAL VSAGWLQEGKGADKIVSTASAVVLRHKF >909|S87R|ARO:3003929|Neisseria gonorrhoeae parC conferring resistance to fluoroquinolones|MEG_5326|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNTQPHASHTDSNTLMLGRYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILFAMRDMGLTAGAKPVKSARVVGEILGK YHPHGDRSAYEAMVRMAQDFTLRYPLIDGIGNFGSRDGDGAAAMRYTEARLTPIAELLLSEINQGTVDFMPNYDGAFDEP LHLPARLPMVLLNGASGIAVGMATEIPSHNLNEVTQAAIALLKKPTLETADLMQYIPAPDFAGGGQIITPADELRRIYET GKGSVRVRARYEIEKLARGQWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDRLNTKKLMLDLIDRVRDESDG EHPVRLVFEPKSSRIDTDTFINTLMAQTSLEGNVSMNLVMMGLDNRPAQKNLKTILQEWLDFRVVTVTRRLKFRLNQVEK RLHILEGRLKVFLHIDEVIKVIRESDDPKADLMAVFGLTEIQAEDILEIRLRQLARLEGFKLEKELNELREEQGRLNIFL GDENEKRKLIIKEMQADMKQFGDARRTLVEEAGRAVLTQTAADEPITLILSEKGWIRSRAGHNLDLSQTAFKEGDRLKQT LEGRTVLPVVILDSSGRTYSIDAAEIPGGRGDGVPVSSLIELQNGAKPVAMLTGLPEQHYLLSSSGGYGFIAKLGDMVGR VKAGKVVMTADSGETVLPPVAVYASSFINPDCKIIAATSQNRALAFPIGELKIMAKGKGLQIIGLNAGESMTHTAVSSEP EILIESEGRRGAAHKDRLPVALIEAKRGKKGRLLPISGSLKQLSSPK >910|E91G|ARO:3003929|Neisseria gonorrhoeae parC conferring resistance to fluoroquinolones|MEG_5326|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNTQPHASHTDSNTLMLGRYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILFAMRDMGLTAGAKPVKSARVVGEILGK YHPHGDSSAYGAMVRMAQDFTLRYPLIDGIGNFGSRDGDGAAAMRYTEARLTPIAELLLSEINQGTVDFMPNYDGAFDEP LHLPARLPMVLLNGASGIAVGMATEIPSHNLNEVTQAAIALLKKPTLETADLMQYIPAPDFAGGGQIITPADELRRIYET GKGSVRVRARYEIEKLARGQWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDRLNTKKLMLDLIDRVRDESDG EHPVRLVFEPKSSRIDTDTFINTLMAQTSLEGNVSMNLVMMGLDNRPAQKNLKTILQEWLDFRVVTVTRRLKFRLNQVEK RLHILEGRLKVFLHIDEVIKVIRESDDPKADLMAVFGLTEIQAEDILEIRLRQLARLEGFKLEKELNELREEQGRLNIFL GDENEKRKLIIKEMQADMKQFGDARRTLVEEAGRAVLTQTAADEPITLILSEKGWIRSRAGHNLDLSQTAFKEGDRLKQT LEGRTVLPVVILDSSGRTYSIDAAEIPGGRGDGVPVSSLIELQNGAKPVAMLTGLPEQHYLLSSSGGYGFIAKLGDMVGR VKAGKVVMTADSGETVLPPVAVYASSFINPDCKIIAATSQNRALAFPIGELKIMAKGKGLQIIGLNAGESMTHTAVSSEP EILIESEGRRGAAHKDRLPVALIEAKRGKKGRLLPISGSLKQLSSPK >911|P551L|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGLPFKKIMGGS LNILGISPTKPLTAAAVKTPS >912|A516G|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVGTFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >913|A311V|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSVIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >914|V316P|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFPIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >915|T483S|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGSGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >916|P551S|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGSPFKKIMGGS LNILGISPTKPLTAAAVKTPS >917|A501T|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTTRKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >918|A501V|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTVRKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >919|G542S|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHSYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >920|F504L|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKLVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >921|A510V|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYVDNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >922|A501P|ARO:3004832|Neisseria gonorrhoeae PBP2 conferring resistance to beta-lactam antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSD RNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTPRKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >923|A39T|ARO:3004851|Neisseria gonorrhoeae mtrR with mutation conferring resistance|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQTAGVTRGALYWHFKNKEDLFDALFQRICDDIENCIAQDAADA EGGSWTVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE TAVIFIKSTLDGLIWRWFSSGESFDLGKTAPRIIGIMMDNLENHPCLRRK >924|L421P|ARO:3004833|Neisseria gonorrhoeae PBP1 conferring resistance to beta-lactam|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVL RNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDK ILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQ QRDQALNEELHYERFVRKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRG AENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEKMGEDRIRR GAVIRVKNNGGRWAVVQEPLPQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTAST VVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMAL GTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGA AALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGV VSSNGEYYMKERMVTDPGLTLDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF >925|E666K|ARO:3004835|Neisseria gonorrhoeae pilQ gene conferring resistance to beta-lactam|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPFTESVV SVSAPFSPAKQQAAASAKQQAATPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTALQRSLD VADFKTPVQKVTLKRLNNDTQLIITTTGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIR TILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADL GALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMI EARIVEAADGFSRDLGVKFGATGRKKLKNETSAFGWGVNSGFGGGDKWEAQTKINLPVAAAANSISLVRAISSGALNLEL SASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTTASGGGNSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDS PAQCASGNNTILCISTKSLNTQAMVKNGGTLIVGGIYEENNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPR IIDTAGNSLRY >926|I312M|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAMKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >927|G482S|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GSTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >928|F504L|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKLVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >929|A510V|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYVDNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >930|V316T|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFTIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >931|N512Y|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADYKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >932|G545S|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYSGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >933|A501P|ARO:3003937|Neisseria meningititis PBP2 conferring resistance to beta-lactam|MEG_5401|Drugs|betalactams|Penicillin_binding_protein|PBP2|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSD RNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLD QRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA LDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGET AGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEP GGTGTAGAVDGFDVGAKTGTPRKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGS LNILGISPTKPLTAAAVKTPS >934|G261S|ARO:3003361|Planobispora rosea EF-Tu mutants conferring resistance to inhibitor GE2270A|MEG_7305|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKFERTKPHMNIGTIGHIDHGKTTLTAAITKVLHDRYPELNKATPFDKIDKAPEEKARGITISIAHVEYQTEKRHYA HVDCPGHADYVKNMITGAAQMDGAILVVAATAGPMPQTKEHVLLARQVGVPYIVVALNKADMVDDEEILELVELEVRELL SAQEFPGDDLPVVRVSALKALEGDEKWADSIIELMNAVDENIPEPPRDTDKPFLMPIEDVFSITGRGTVVTGRIERGVVK VNEQVDIIGIKSEKTTTTVTSIEMFNKMLDEGHAGDNVGLLLRGIKREQVERGQVIIKPGTTTPHTEFEAQVYILSKDEG GRHTPFFNNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNTEMTVQLIQPIAMEEGLKFAIREGGRTVGAGRVTKILK >935|V295C|ARO:3003361|Planobispora rosea EF-Tu mutants conferring resistance to inhibitor GE2270A|MEG_7305|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKFERTKPHMNIGTIGHIDHGKTTLTAAITKVLHDRYPELNKATPFDKIDKAPEEKARGITISIAHVEYQTEKRHYA HVDCPGHADYVKNMITGAAQMDGAILVVAATAGPMPQTKEHVLLARQVGVPYIVVALNKADMVDDEEILELVELEVRELL SAQEFPGDDLPVVRVSALKALEGDEKWADSIIELMNAVDENIPEPPRDTDKPFLMPIEDVFSITGRGTVVTGRIERGVVK VNEQVDIIGIKSEKTTTTVTGIEMFNKMLDEGHAGDNVGLLLRGIKREQVERGQCIIKPGTTTPHTEFEAQVYILSKDEG GRHTPFFNNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNTEMTVQLIQPIAMEEGLKFAIREGGRTVGAGRVTKILK >936|G279A|ARO:3003361|Planobispora rosea EF-Tu mutants conferring resistance to inhibitor GE2270A|MEG_7305|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKFERTKPHMNIGTIGHIDHGKTTLTAAITKVLHDRYPELNKATPFDKIDKAPEEKARGITISIAHVEYQTEKRHYA HVDCPGHADYVKNMITGAAQMDGAILVVAATAGPMPQTKEHVLLARQVGVPYIVVALNKADMVDDEEILELVELEVRELL SAQEFPGDDLPVVRVSALKALEGDEKWADSIIELMNAVDENIPEPPRDTDKPFLMPIEDVFSITGRGTVVTGRIERGVVK VNEQVDIIGIKSEKTTTTVTGIEMFNKMLDEGHAGDNVALLLRGIKREQVERGQVIIKPGTTTPHTEFEAQVYILSKDEG GRHTPFFNNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNTEMTVQLIQPIAMEEGLKFAIREGGRTVGAGRVTKILK >937|V278A|ARO:3003361|Planobispora rosea EF-Tu mutants conferring resistance to inhibitor GE2270A|MEG_7305|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKFERTKPHMNIGTIGHIDHGKTTLTAAITKVLHDRYPELNKATPFDKIDKAPEEKARGITISIAHVEYQTEKRHYA HVDCPGHADYVKNMITGAAQMDGAILVVAATAGPMPQTKEHVLLARQVGVPYIVVALNKADMVDDEEILELVELEVRELL SAQEFPGDDLPVVRVSALKALEGDEKWADSIIELMNAVDENIPEPPRDTDKPFLMPIEDVFSITGRGTVVTGRIERGVVK VNEQVDIIGIKSEKTTTTVTGIEMFNKMLDEGHAGDNAGLLLRGIKREQVERGQVIIKPGTTTPHTEFEAQVYILSKDEG GRHTPFFNNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNTEMTVQLIQPIAMEEGLKFAIREGGRTVGAGRVTKILK >938|S80L|ARO:3003702|Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolones|MEG_5325|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSESLDLSLEGVERRSLAEFTEQAYLNYSMYVIMDRALPHIGDGLKPVQRRIVYAMSELGLDADSKHKKSARTVGDVLGL FHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTEARLSRYSEVLLSELGQGTVDWVPNFDGTLDE PAVLPARLPNLLLNGTTGIAVGMATDVPPHNLREVASACVRLLDQPGATVAELCEHVPGPDFPTEAEIITPRADLQKVYE TGRGSVRMRAVYRFEDGDIVIHALPHQVSGSKVLEQIAGQMQAKKLPMVADLRDESDHENPTRIVIIPRSNRVDVEELMT HLFATTDLETSYRVNLNIIGLDGKPAVKDLRQLLSEWLQFRIGTVRRRLQFRLDKVERRLHLLDGLLIAFLNLDEVIHII RTEDQPKAVLMERFELSEVQADYILDTRLRQLARLEEMKIRGEQEELLKEQKRLQTLLGSEAKLKKLVREELIKDAETYG DDRRSPIVARAEARALSETELMPTEPVTVVLSEKGWVRCAKGHDIDAAGLSYKAGDGFKAAAPGRSNQYAVFIDSTGRSY SLPAHSLPSARGQGEPLSGRLTPPPGASFECVLLPDDDALFVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNGSAVVAP RPVRDVEQDWLAAVTTEGRLLLFKVSDLPQLGKGKGNKIIGIPGERVASREEYLTDLAVLPAGATLVLQAGKRTLSLKGD DLEHYKGERGRRGNKLPRGFQRVDSLLVDIPPQD >939|H80R|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPR GDTAVYDTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >940|T83I|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPH GDIAVYDTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >941|D87N|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPH GDTAVYNTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >942|R154A|ARO:3003390|Escherichia coli ompF with mutation conferring resistance to beta-lactam antibiotics|MEG_4289|Drugs|betalactams|Mutant_porin_proteins|OMPFB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGY GQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGAVGGVAT YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGL KYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG ATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF >943|G141D|ARO:3003390|Escherichia coli ompF with mutation conferring resistance to beta-lactam antibiotics|MEG_4289|Drugs|betalactams|Mutant_porin_proteins|OMPFB|RequiresSNPConfirmation|Escherichia|WP_000977920.1|141|ompF_G141D|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_OmpF|wt_coherence=TRUE MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGY GQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFDGDTAYSDDFFVGRVGGVAT YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGL KYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG ATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF >944|G141E|ARO:3003390|Escherichia coli ompF with mutation conferring resistance to beta-lactam antibiotics|MEG_4289|Drugs|betalactams|Mutant_porin_proteins|OMPFB|RequiresSNPConfirmation|Escherichia|WP_000977920.1|141|ompF_G141E|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_OmpF|wt_coherence=TRUE MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGY GQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFEGDTAYSDDFFVGRVGGVAT YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGL KYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG ATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF >945|R154D|ARO:3003390|Escherichia coli ompF with mutation conferring resistance to beta-lactam antibiotics|MEG_4289|Drugs|betalactams|Mutant_porin_proteins|OMPFB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGY GQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGDVGGVAT YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGL KYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG ATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF >946|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMGPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >947|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMAPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >948|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMVPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >949|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMLPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >950|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMIPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >951|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMPPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >952|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMFPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >953|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMYPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >954|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMWPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >955|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMSPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >956|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMTPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >957|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMNPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >958|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMQPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >959|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMCPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >960|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMMPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >961|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMDPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >962|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMEPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >963|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMHPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >964|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMKPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >965|Q142X|ARO:3003686|Pseudomonas aeruginosa oprD with mutation conferring resistance to imipenem|MEG_4296|Drugs|betalactams|Mutant_porin_proteins|OPRD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQG TVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMRPTAPVFAAGGSRLFPQTA TGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNS NYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI FLANSVQYSDFNGPGEKSWQARYDLNLASYGVPGLTFMVRYINGKDIDGTKMSDNNVGYKNYGYGEDGKHHETNLEAKYV VQSGPAKDLSFRIRQAWHRANADQGEGDQNEFRLIVDYPLSIL >966|M437I|ARO:3003685|Pseudomonas aeruginosa parE conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATYNADAIEVLSGLDPVRKRPGMYTDTTRPNHLAQEVIDNSVDEALAGHAKSVQVILHQDNSLEVIDDGRGMPVDIHPE EGVPGVELILTKLHAGGKFSNKNYQFSGGLHGVGISVVNALSTRVEVRVKRDANEYRMTFADGFKDSDLEVIGTVGKRNT GTSVHFWPDPKYFDSAKFSVSRLKHVLKAKAVLCPGLSVVFEDKNTGERVEWHFEDGLRSYLTDAVAELPRLPDEPFCGN LEGSKEAVSWALLWLPEGGESVQESYVNLIPTAQGGTHVNGLRQGLLDAMREFCEFRNLLPRGVKLAPEDVWERIAFVLS MKMQEPQFSGQTKERLSSREAAAFVSGVVKDAFSLWLNEHAEIGLQLAELAISNAGRRLKAGKKVERKKITQGPALPGKL ADCAGQEPMRAELFLVEGDSAGGSAKQARDKEFQAIIPLRGKILNTWEVDGGEVLASQEVHDIAVAIGVDPGASDLAQLR YGKICILADADSDGLHIATLLCALFVRHFRPLVEAGHVYVAMPPLYRIDLGKDIYYALDEAERDGILERLAAEKKRGKPQ VTRFKGLGEMNPLQLRETTMDPNTRRLVQLTLEDATGTLEIMDMLLAKKRAGDRKSWLESKGNLAEVLV >967|A473V|ARO:3003685|Pseudomonas aeruginosa parE conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATYNADAIEVLSGLDPVRKRPGMYTDTTRPNHLAQEVIDNSVDEALAGHAKSVQVILHQDNSLEVIDDGRGMPVDIHPE EGVPGVELILTKLHAGGKFSNKNYQFSGGLHGVGISVVNALSTRVEVRVKRDANEYRMTFADGFKDSDLEVIGTVGKRNT GTSVHFWPDPKYFDSAKFSVSRLKHVLKAKAVLCPGLSVVFEDKNTGERVEWHFEDGLRSYLTDAVAELPRLPDEPFCGN LEGSKEAVSWALLWLPEGGESVQESYVNLIPTAQGGTHVNGLRQGLLDAMREFCEFRNLLPRGVKLAPEDVWERIAFVLS MKMQEPQFSGQTKERLSSREAAAFVSGVVKDAFSLWLNEHAEIGLQLAELAISNAGRRLKAGKKVERKKITQGPALPGKL ADCAGQEPMRAELFLVEGDSAGGSAKQARDKEFQAIMPLRGKILNTWEVDGGEVLASQEVHDIAVAIGVDPGVSDLAQLR YGKICILADADSDGLHIATLLCALFVRHFRPLVEAGHVYVAMPPLYRIDLGKDIYYALDEAERDGILERLAAEKKRGKPQ VTRFKGLGEMNPLQLRETTMDPNTRRLVQLTLEDATGTLEIMDMLLAKKRAGDRKSWLESKGNLAEVLV >968|A110V|ARO:3003895|Pseudomonas mutant PhoP conferring resistance to colistin|MEG_5784|Drugs|Lipopeptides|Colistin-resistant_mutant|PHOP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTA RGNWQDKVEGLAAGADDYVVKPFQFEELEVRLNALLRRSSGFVQSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEY LMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFTERCR >969|R117L|ARO:3003895|Pseudomonas mutant PhoP conferring resistance to colistin|MEG_5784|Drugs|Lipopeptides|Colistin-resistant_mutant|PHOP|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTA RGNWQDKVEGLAAGADDYVVKPFQFEELEARLNALLLRSSGFVQSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEY LMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFTERCR >970|K123Q|ARO:3003896|Pseudomonas mutant PhoQ conferring resistance to colistin|MEG_5785|Drugs|Lipopeptides|Colistin-resistant_mutant|PHOQ|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MIRSLRIRLMLGAAALAVLFMLALLPALQRAFGIALENTIEQRLAADVATLVSAARVEKGRLVMPEHLPVEEFNLPEAKV LGYIYDQNGDLLWRSTSAADESINYTPRYDGRGNEFHTTRDAQGEEFFVFDVEIDLLRGKQAAYSIVTMQSVSEFESLLK GFREQLYLWLGGALLVLLGLLWLGLTWGFRAMRGLSSELDQIESGERESLSEEHPRELLRLTHSLNRLLRSEHKQRERYR HSLGDLAHSLKTPLAVLQGVGDQLAEEPGNREQVRVLQGQIERMSQQIGYQLQRASLRKSGLVRHREQLAPLVETLCDAL DKVYRDKRVSLQRDFSPSFSVPVERGALLELLGNLLENAYRLCLGRVRVGARLGPGYSELWVEDDGPGVPAEQRARIIRR GERADTQHPGQGIGLAVALDIIESYDGELSLDDSELGGACFRIRFATV >971|V260G|ARO:3003896|Pseudomonas mutant PhoQ conferring resistance to colistin|MEG_5785|Drugs|Lipopeptides|Colistin-resistant_mutant|PHOQ|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MIRSLRIRLMLGAAALAVLFMLALLPALQRAFGIALENTIEQRLAADVATLVSAARVEKGRLVMPEHLPVEEFNLPEAKV LGYIYDQNGDLLWRSTSAADESINYTPRYDGRGNEFHTTRDAKGEEFFVFDVEIDLLRGKQAAYSIVTMQSVSEFESLLK GFREQLYLWLGGALLVLLGLLWLGLTWGFRAMRGLSSELDQIESGERESLSEEHPRELLRLTHSLNRLLRSEHKQRERYR HSLGDLAHSLKTPLAVLQGGGDQLAEEPGNREQVRVLQGQIERMSQQIGYQLQRASLRKSGLVRHREQLAPLVETLCDAL DKVYRDKRVSLQRDFSPSFSVPVERGALLELLGNLLENAYRLCLGRVRVGARLGPGYSELWVEDDGPGVPAEQRARIIRR GERADTQHPGQGIGLAVALDIIESYDGELSLDDSELGGACFRIRFATV >972|G70D|ARO:3004956|Neisseria gonorrhoeae rpld|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MELKVIDAKGQVSGSLSVSDALFAREYNEALVHQLVNAYLANARSGNRAQKTRAEVKHSTKKPWRQKGTDRARSGMTSSP LWRKGGRAFPNKPDENFTQKVNRKMYRAGMATILSQLARDERLFVIEALTAETPKTKVFAEQVKNLALEQVLFVTKRLDE NVYLASRNLPNVLVLEAQQVDPYSLLRYKKVIITKDAVAQLEEQWV >973|V57L|ARO:3003930|rpsJ|MEG_6143|Drugs|Tetracyclines|Tetracycline_resistance_ribosomal_protection_proteins|RPSJ|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRSPHLNKTSREQLEIRTHLRLMDIVDWT DKTTDALMKLDLPAGVDVEIKVQ >974|V57M|ARO:3003930|rpsJ|MEG_6143|Drugs|Tetracyclines|Tetracycline_resistance_ribosomal_protection_proteins|RPSJ|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRSPHMNKTSREQLEIRTHLRLMDIVDWT DKTTDALMKLDLPAGVDVEIKVQ >975|D87Y|ARO:3003926|Salmonella enterica gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|87|gyrA_D87Y|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYYTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >976|S97P|ARO:3003926|Salmonella enterica gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|97|gyrA_S97P|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFPLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >977|D87N|ARO:3003926|Salmonella enterica gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|87|gyrA_D87N|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >978|D87G|ARO:3004334|Salmonella enterica gyrA with mutation conferring resistance to triclosan|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|87|gyrA_D87G|QUINOLONE/TRICLOSAN|QUINOLONE/TRICLOSAN|Salmonella_quinolone/triclosan_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYGTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >979|S83F|ARO:3004334|Salmonella enterica gyrA with mutation conferring resistance to triclosan|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|83|gyrA_S83F|QUINOLONE/TRICLOSAN|QUINOLONE/TRICLOSAN|Salmonella_quinolone/triclosan_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDFAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >980|W106G|ARO:3003939|Salmonella enterica parC conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNGGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVISALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRSEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADADAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKTLITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >981|T18P|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|18|ramR_T18P|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAAPQAIAQSGIAASTAVIARNAGVAEGTLFRYFATKDELINTLYLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >982|Y59H|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|59|ramR_Y59H|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGVAEGTLFRYFATKDELINTLHLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >983|R46P|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|46|ramR_R46P|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGVAEGTLFPYFATKDELINTLYLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >984|M84I|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|84|ramR_M84I|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGVAEGTLFRYFATKDELINTLYLHLKQDLCQSMIMELDRSITD AKMITRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >985|T50P|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|50|ramR_T50P|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGVAEGTLFRYFAPKDELINTLYLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >986|E160D|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|160|ramR_E160D|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGVAEGTLFRYFATKDELINTLYLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAD TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >987|G25A|ARO:3003379|Salmonella enterica ramR mutants|MEG_6046|Drugs|Multi-drug_resistance|Multi-drug_RND_efflux_regulator|RAMR|RequiresSNPConfirmation|Salmonella|WP_000113609.1|25|ramR_G25A|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_RamR|wt_coherence=TRUE MARPKSEDKKQALLEAATQAIAQSAIAASTAVIARNAGVAEGTLFRYFATKDELINTLYLHLKQDLCQSMIMELDRSITD AKMMTRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE TTMDFAARDPARAGEYIALGFEAMWRALTREEQ >988|R20H|ARO:3003382|Salmonella enterica soxR with mutation conferring antibiotic resistance|MEG_6548|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_ABC_efflux_regulator|SOXR|RequiresSNPConfirmation|Salmonella|WP_000412686.1|20|soxR_R20H|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxR|wt_coherence=TRUE MEKKSPRLKALLTPGEVAKHSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGDAFGIL PEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEHGTGARLLEDD >989|G121D|ARO:3003382|Salmonella enterica soxR with mutation conferring antibiotic resistance|MEG_6548|Multi-compound|Drug_and_biocide_resistance|Drug_and_biocide_ABC_efflux_regulator|SOXR|RequiresSNPConfirmation|Salmonella|WP_000412686.1|121|soxR_G121D|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxR|wt_coherence=TRUE MEKKSPRLKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGDAFGIL PEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIDCGCLSRSDCPLRNPGDRLGEHGTGARLLEDD >990|E466D|ARO:3003307|Salmonella serovars gyrB conferring resistance to fluoroquinolones|MEG_3238|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|Salmonella|WP_000072047.1|466|gyrB_E466D|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQDVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >991|V461G|ARO:3003317|Salmonella serovars parE conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|461|parE_V461G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEGHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >992|E52K|ARO:3003383|Salmonella serovars soxS with mutation conferring antibiotic resistance|MEG_6552|Multi-compound|Drug_and_biocide_and_metal_resistance|Drug_and_biocide_and_metal_resistance_regulator|SOXS|RequiresSNPConfirmation|Salmonella|WP_000019483.1|52|soxS_E52K|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Salmonella_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxS|wt_coherence=TRUE MSHQQIIQTLIEWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGKYIRQRRLLLAAVELRTTERPIFDIAMDL GYVSQQTFSRVFRREFDRTPSDYRHRL >993|N57K|ARO:3003940|Shigella flexneri gyrA conferring resistance to fluoroquinolones|MEG_3178|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGKDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >994|H80P|ARO:3003940|Shigella flexneri gyrA conferring resistance to fluoroquinolones|MEG_3178|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPP GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >995|S129P|ARO:3003941|Shigella flexneri parC conferring resistance to fluoroquinolones|MEG_5332|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|Escherichia|WP_001281881.1|129|parC_S129P|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYPELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >996|D111H|ARO:3003941|Shigella flexneri parC conferring resistance to fluoroquinolones|MEG_5332|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|Escherichia|WP_001281881.1|111|parC_D111H|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDHPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >997|A85T|ARO:3003941|Shigella flexneri parC conferring resistance to fluoroquinolones|MEG_5332|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|Escherichia|WP_001281881.1|85|parC_A85T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYETMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >998|L52F|ARO:3003074|Staphylococcus aureus cls conferring resistance to daptomycin|MEG_1730|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000571549.1|52|cls_L52F|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_Cls|wt_coherence=TRUE MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVFVFLPLFGFILYLLLGRQIQRDQIFKIDK EDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVI DGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIAS SGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAG VKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWI KFKEGISQLLSPIL >999|T33N|ARO:3003074|Staphylococcus aureus cls conferring resistance to daptomycin|MEG_1730|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000571549.1|33|cls_T33N|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_Cls|wt_coherence=TRUE MIELLSIALKHSNIILNSIFIGAFILNLLFAFNIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDK EDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVI DGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIAS SGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAG VKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWI KFKEGISQLLSPIL >1000|F60S|ARO:3003074|Staphylococcus aureus cls conferring resistance to daptomycin|MEG_1730|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000571549.1|60|cls_F60S|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_Cls|wt_coherence=TRUE MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGSILYLLLGRQIQRDQIFKIDK EDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVI DGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIAS SGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAG VKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWI KFKEGISQLLSPIL >1001|A23V|ARO:3003074|Staphylococcus aureus cls conferring resistance to daptomycin|MEG_1730|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CLS|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000571549.1|23|cls_A23V|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_Cls|wt_coherence=TRUE MIELLSIALKHSNIILNSIFIGVFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDK EDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVI DGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIAS SGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAG VKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYAKRSLWI KFKEGISQLLSPIL >1002|V213I|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001010116.1|213|glpT_V213I|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_GlpT|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1003|W137R|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGRPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1004|F3I|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNILKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1005|L27F|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRFQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1006|A100V|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1007|G352D|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPDNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1008|S85P|ARO:3003296|Staphylococcus aureus gyrA conferring resistance to fluoroquinolones|MEG_3186|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSPIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFENLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1009|E88K|ARO:3003296|Staphylococcus aureus gyrA conferring resistance to fluoroquinolones|MEG_3186|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYKAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFENLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1010|S84L|ARO:3003296|Staphylococcus aureus gyrA conferring resistance to fluoroquinolones|MEG_3186|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDLSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFENLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1011|E88A|ARO:3003296|Staphylococcus aureus gyrA conferring resistance to fluoroquinolones|MEG_3186|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYAAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFENLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1012|R143S|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|143|gyrB_R143S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHSNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1013|I55S|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|55|gyrB_I55S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSSDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1014|T172A|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|172|gyrB_T172A|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGAVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1015|I101S|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|101|gyrB_I101S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVSLTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1016|S128L|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSLVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1017|G84S|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|84|gyrB_G84S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRSIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1018|R143I|ARO:3003301|Staphylococcus aureus gyrB conferring resistance to aminocoumarin|MEG_3245|Drugs|Aminocoumarins|Aminocoumarin-resistant_DNA_topoisomerases|GYRBA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_010956585.1|143|gyrB_R143I|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHINETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1019|V588F|ARO:3003729|Staphylococcus aureus ileS with mutation conferring resistance to mupirocin|MEG_3296|Drugs|Mupirocin|Mupirocin-resistant_isoleucyl-tRNA_synthetase|ILES|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000384706.1|588|ileS_V588F|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWFNSSITTSVATRGVSPYKFLLSHGFFMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1020|V631F|ARO:3003729|Staphylococcus aureus ileS with mutation conferring resistance to mupirocin|MEG_3296|Drugs|Mupirocin|Mupirocin-resistant_isoleucyl-tRNA_synthetase|ILES|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000384706.1|631|ileS_V631F|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADFRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1021|G33D|ARO:3003917|Staphylococcus aureus menA with mutation conferring resistance to lysocin|MEG_3831|Drugs|Lipopeptides|Lysocin-resistant_mutant|MENA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSNQYQQYSTVKKYWHLMRPHTLTASVVPVLVDTAASKIYFLGSEDHIKISLFIAMLLACLLIQAATNMFNEYYDYKKGL DDHESVGIGGAIVRNGMSPELVLRLAIAFYILAAILGLFLAANSSFWLLPVGLVCMAVGYLYTGGPFPISWTPFGELFSG VFMGMFIIVIAFFIQTGNIQSYVIWLSVPIVITIGLINMANNIRDRVKDKASGRKTLPILLGKNASLTFMAIMYFIAYAF IVLTIIIKPGGSLFYLLALLSFPMPVKVIRRFKKNDTPPTMMPAMAAAGKTNTFFGLLYALGIYISALFAGI >1022|T345K|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFKSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1023|T472K|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYAKDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1024|M347R|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSRINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1025|I420N|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITNLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1026|L826F|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESFSKVMRVIRHK >1027|P314L|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFILAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1028|I418N|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILNTWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1029|S295L|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSLFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1030|G61V|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGVASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1031|L341S|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAISVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1032|S337L|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLLLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1033|T345A|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFASMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1034|F57S|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLSIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1035|T345I|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFISMINLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1036|V351E|ARO:3003319|Staphylococcus aureus mprF with mutation conferring resistance to daptomycin|MEG_4057|Drugs|Lipopeptides|Daptomycin-resistant_mutant|MPRFD|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMINLEIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMIS ILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMH TSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYK ASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFR ATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYF NDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRR YKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1037|G257D|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRDAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1038|E291D|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000358006.1|291|murA_E291D|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1039|Q362R|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSRLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1040|D278E|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000358006.1|278|murA_D278E|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1041|T396N|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELNHLDR GYVDLHGKLKQLGADIERIND >1042|V65L|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADLTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELEYQEDGIRVRAEGDLQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1043|S80Y|ARO:3003312|Staphylococcus aureus parC conferring resistance to fluoroquinolones|MEG_5329|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDY SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITVITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1044|E84G|ARO:3003312|Staphylococcus aureus parC conferring resistance to fluoroquinolones|MEG_5329|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYGAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITVITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1045|S80F|ARO:3003312|Staphylococcus aureus parC conferring resistance to fluoroquinolones|MEG_5329|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDF SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITVITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1046|G78S|ARO:3003314|Staphylococcus aureus parE conferring resistance to aminocoumarin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRSMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1047|R136G|ARO:3003314|Staphylococcus aureus parE conferring resistance to aminocoumarin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHGDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1048|D434H|ARO:3003315|Staphylococcus aureus parE conferring resistance to fluoroquinolones|MEG_5395|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PAREF|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAMNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRG MPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKK GKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEV LHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIR EGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARS GKKNKRKDTLLSGKLTPAQSKNTDKNELYLVEGHSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIH TIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTD EELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHFEFGM QEDQSILDNSEVQVLENDQFDEEEI >1049|P587S|ARO:3003315|Staphylococcus aureus parE conferring resistance to fluoroquinolones|MEG_5395|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PAREF|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAMNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRG MPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKK GKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEV LHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIR EGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARS GKKNKRKDTLLSGKLTPAQSKNTDKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIH TIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTD EELNKLQKELGKGFTLQRYKGLGEMNSEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHFEFGM QEDQSILDNSEVQVLENDQFDEEEI >1050|D434N|ARO:3003315|Staphylococcus aureus parE conferring resistance to fluoroquinolones|MEG_5395|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PAREF|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAMNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRG MPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKK GKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEV LHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIR EGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARS GKKNKRKDTLLSGKLTPAQSKNTDKNELYLVEGNSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIH TIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTD EELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHFEFGM QEDQSILDNSEVQVLENDQFDEEEI >1051|S177F|ARO:3003323|Staphylococcus aureus pgsA mutations conferring resistance to daptomycin|MEG_5780|Drugs|Lipopeptides|Daptomycin-resistant_mutant|PGSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001025093.1|177|pgsA_S177F|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_PgsA|wt_coherence=TRUE MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPL ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL SLGQILLYIGVIFTILFGIEYFYKGRDVFKQK >1052|A64V|ARO:3003323|Staphylococcus aureus pgsA mutations conferring resistance to daptomycin|MEG_5780|Drugs|Lipopeptides|Daptomycin-resistant_mutant|PGSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001025093.1|64|pgsA_A64V|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_PgsA|wt_coherence=TRUE MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLVRKWNLVTNMGKFLDPL ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK >1053|K66R|ARO:3003323|Staphylococcus aureus pgsA mutations conferring resistance to daptomycin|MEG_5780|Drugs|Lipopeptides|Daptomycin-resistant_mutant|PGSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001025093.1|66|pgsA_K66R|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_PgsA|wt_coherence=TRUE MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLARRWNLVTNMGKFLDPL ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK >1054|V59N|ARO:3003323|Staphylococcus aureus pgsA mutations conferring resistance to daptomycin|MEG_5780|Drugs|Lipopeptides|Daptomycin-resistant_mutant|PGSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001025093.1|59|pgsA_V59N|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_PgsA|wt_coherence=TRUE MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFNDGYLARKWNLVTNMGKFLDPL ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK >1055|A621E|ARO:3003287|Staphylococcus aureus rpoB mutants conferring resistance to daptomycin|MEG_6137|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|621|rpoB_A621E|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAETACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1056|I953S|ARO:3003287|Staphylococcus aureus rpoB mutants conferring resistance to daptomycin|MEG_6137|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|953|rpoB_I953S|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPSDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1057|A1085V|ARO:3003287|Staphylococcus aureus rpoB mutants conferring resistance to daptomycin|MEG_6137|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|1085|rpoB_A1085V|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEVYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1058|H481N|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|481|rpoB_H481N|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT NKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1059|Q468K|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|468|rpoB_Q468K|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSKFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1060|A473T|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|473|rpoB_A473T|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQTNPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1061|Q465R|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|465|rpoB_Q465R|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSRLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1062|L466S|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|466|rpoB_L466S|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQSSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1063|A477T|ARO:3003285|Staphylococcus aureus rpoB mutants conferring resistance to rifampicin|MEG_6136|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOBL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000918664.1|477|rpoB_A477T|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLTELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1064|Q961K|ARO:3003291|Staphylococcus aureus rpoC conferring resistance to daptomycin|MEG_6139|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoC|RPOCL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000567963.1|961|rpoC_Q961K|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_RpoC|wt_coherence=TRUE MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGV EVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYD KYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRP MVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHML KGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDV LEEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNIL NPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILAT SVGKIIFNEIIPDSFAYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFNRFSITDT SMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERYNAVVEIWTDAKDQIQGEL MQSLDKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTAD SGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEVIIRPDELITPEIAKKI TDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRI KEIFEARNPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYLS VAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKHRKRPATA KPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVE SQTEVTE >1065|F632S|ARO:3003291|Staphylococcus aureus rpoC conferring resistance to daptomycin|MEG_6139|Drugs|Lipopeptides|Daptomycin-resistant_beta-subunit_of_RNA_polymerase_RpoC|RPOCL|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000567963.1|632|rpoC_F632S|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_RpoC|wt_coherence=TRUE MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGV EVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYD KYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRP MVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHML KGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDV LEEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNIL NPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILAT SVGKIIFNEIIPDSFAYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVSNRFSITDT SMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERYNAVVEIWTDAKDQIQGEL MQSLDKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTAD SGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEVIIRPDELITPEIAKKI TDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRI QEIFEARNPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYLS VAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKHRKRPATA KPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVE SQTEVTE >1066|G358V|ARO:3003902|Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin|MEG_7329|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001008722.1|358|uhpT_G358V|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_UhpT|wt_coherence=TRUE MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALVALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA KVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI >1067|W425R|ARO:3003902|Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin|MEG_7329|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001008722.1|425|uhpT_W425R|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_UhpT|wt_coherence=TRUE MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA KVGLAAIADPTRNGLNIFGYTLSGRTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI >1068|G112E|ARO:3003902|Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin|MEG_7329|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001008722.1|112|uhpT_G112E|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_UhpT|wt_coherence=TRUE MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG KTLLGYFVDGRNTKRIISFLLILSAITVLIMEFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA KVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI >1069|S221P|ARO:3003794|Staphylococcus aureus walK with mutation conferring resistance to daptomycin|MEG_7806|Drugs|Lipopeptides|Daptomycin-resistant_mutant|WALK|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000871610.1|221|walK_S221P|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_WalK|wt_coherence=TRUE MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLL SEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKV IGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMPRGNYTQRVKIYGNDEIGEL ALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKL EEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEA LEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSTKDTTFIRDIPKK TIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMG GTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE >1070|R263C|ARO:3003794|Staphylococcus aureus walK with mutation conferring resistance to daptomycin|MEG_7806|Drugs|Lipopeptides|Daptomycin-resistant_mutant|WALK|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000871610.1|263|walK_R263C|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_WalK|wt_coherence=TRUE MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLL SEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKV IGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGEL ALAFNNLSKRVQEAQANTESEKCRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKL EEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEA LEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSTKDTTFIRDIPKK TIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMG GTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE >1071|L10F|ARO:3003794|Staphylococcus aureus walK with mutation conferring resistance to daptomycin|MEG_7806|Drugs|Lipopeptides|Daptomycin-resistant_mutant|WALK|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000871610.1|10|walK_L10F|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_WalK|wt_coherence=TRUE MKWLKQLQSFHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLL SEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKV IGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGEL ALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKL EEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEA LEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSTKDTTFIRDIPKK TIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMG GTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE >1072|F88L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|88|fusA_F88L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDLTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1073|Q115L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|115|fusA_Q115L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPLTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1074|P404Q|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|404|fusA_P404Q|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFQEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1075|V407F|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|407|fusA_V407F|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPFIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1076|D434N|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|434|fusA_D434N|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEENPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1077|G451V|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|451|fusA_G451V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIVGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1078|R464S|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|464|fusA_R464S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDSMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1079|A376V|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|376|fusA_A376V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAVAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1080|G452C|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|452|fusA_G452C|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGCMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1081|L461S|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|461|fusA_L461S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDISVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1082|G452S|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|452|fusA_G452S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGSMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1083|G452V|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|452|fusA_G452V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGVMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1084|R464H|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|464|fusA_R464H|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDHMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1085|R464L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|464|fusA_R464L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDLMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1086|L461F|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|461|fusA_L461F|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDIFVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1087|T436I|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|436|fusA_T436I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPIFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1088|H457Y|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|457|fusA_H457Y|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELYLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1089|V90I|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|90|fusA_V90I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTIEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1090|V90A|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|90|fusA_V90A|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTAEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1091|F441Y|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHYDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1092|L456F|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|456|fusA_L456F|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGEFHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1093|R464C|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|464|fusA_R464C|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDCMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1094|P406L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|406|fusA_P406L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPELVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1095|L461K|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|461|fusA_L461K|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDIKVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1096|P404L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|404|fusA_P404L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFLEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1097|M453I|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|453|fusA_M453I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGIGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1098|H457Q|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000090315.1|457|fusA_H457Q|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELQLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1099|Q140L|ARO:3003737|Staphylococcus aureus fusE with mutation conferring resistance to fusidic acid|MEG_3071|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSE|RequiresSNPConfirmation|Staphylococcus_aureus|WP_000091975.1|140|fusE_Q140L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusE|wt_coherence=TRUE MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVS QGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKELVGALASNIRSVRPPEPYKGK GIRYQGEYVRRKEGKTGK >1100|D222N|ARO:3004097|Streptococcus mitis CdsA with mutation conferring daptomycin resistance|MEG_1642|Drugs|Lipopeptides|Daptomycin-resistant_mutant|CDSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTKDLQKRTLFAVLALAIFLPVLFAGGLLLQIGIGLLAMLGVHELLHMKGLKTMTIEGALTLFATFALTVPLENYLTFLP VDGNVVAYSVLITIMLGTTVFSKNYTIEDAAFPIAVSFYVGFGFNALLDARVAGFDKVLLALFIVWATDSAAYLTGMNFG KHKLAPRVSPNKSIEGFVGGILGAVLITVIFMLVDSTVALPYGIYRMSLFAAFFSVAGQFGNLIESAMKRHFGVKDSGKF IPGHGGVLDRFDSMLIVFPMMHLFGLF >1101|S82F|ARO:3003311|Streptococcus pneumoniae parC conferring resistance to fluoroquinolones|MEG_5327|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MYLMSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHG DFSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPA AFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVV VRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFK YTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASEN KADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATP RLSSLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNV IYRPIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAK LKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRV SIEEILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSN GSFISDTISDEEVFDAYLQEVVTEDK >1102|D86H|ARO:3003311|Streptococcus pneumoniae parC conferring resistance to fluoroquinolones|MEG_5327|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MYLMSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHG DSSIYHAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPA AFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVV VRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFK YTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASEN KADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATP RLSSLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNV IYRPIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAK LKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRV SIEEILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSN GSFISDTISDEEVFDAYLQEVVTEDK >1103|S82Y|ARO:3003311|Streptococcus pneumoniae parC conferring resistance to fluoroquinolones|MEG_5327|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MYLMSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHG DYSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPA AFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVV VRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFK YTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASEN KADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATP RLSSLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNV IYRPIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAK LKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRV SIEEILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSN GSFISDTISDEEVFDAYLQEVVTEDK >1104|N609D|ARO:3003041|Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin|MEG_5399|Drugs|betalactams|Penicillin_binding_protein|PBP1A|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNKPTILHLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSESKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIP TDLVKAIVSIEDHRFFDHRGIDTIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKTQEAWLAIQLEQK ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDPYSHPEAAQDRRNLVLSEMKNQG YISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYLKEVINQVEKETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYV AYPDDELQVASTIVDVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTATIVHDEPYN YPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLNGLGIDYPSIHYSNAISSNTTESDKKYGASS EKMAAAYAAFANGGTYYKPMYIHKVVFSDGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGT SNYTDEEIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGDGLTVAAKVYRSMMTYLSEGSNPEDWNIPEGL YRNGEFVFKNGARSTWTQPAPQQPPSTESSSSSSDSSTSQSSSTTPSTNNSTTTDPNNNTQQSNTTPDQQNQNPQPAQP >1105|S575T|ARO:3003041|Streptococcus pneumoniae PBP1a conferring resistance to amoxicillin|MEG_5399|Drugs|betalactams|Penicillin_binding_protein|PBP1A|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNKPTILHLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSESKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIP TDLVKAIVSIEDHRFFDHRGIDTIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKTQEAWLAIQLEQK ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDPYSHPEAAQDRRNLVLSEMKNQG YISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYLKEVINQVEKETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYV AYPDDELQVASTIVDVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTATIVHDEPYN YPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLNGLGIDYPSIHYSNAISSNTTESDKKYGASS EKMAAAYAAFANGGTYYKPMYIHKVVFSDGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGT SNYTDEEIENHIKTTQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTYLSEGSNPEDWNIPEGL YRNGEFVFKNGARSTWTQPAPQQPPSTESSSSSSDSSTSQSSSTTPSTNNSTTTDPNNNTQQSNTTPDQQNQNPQPAQP >1106|T488A|ARO:3003042|Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin|MEG_5406|Drugs|betalactams|Penicillin_binding_protein|PBP2B|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKITSSSARGEIYDASGKPLVENT LKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLA FQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISS GWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM EKLRSTFAEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNND KGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAV AYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN >1107|E475G|ARO:3003042|Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin|MEG_5406|Drugs|betalactams|Penicillin_binding_protein|PBP2B|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKITSSSARGEIYDASGKPLVENT LKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLA FQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISS GWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSGLESAM EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNND KGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAV AYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN >1108|T445A|ARO:3003042|Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin|MEG_5406|Drugs|betalactams|Penicillin_binding_protein|PBP2B|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKITSSSARGEIYDASGKPLVENT LKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLA FQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISS GWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQAAEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNND KGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAV AYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN >1109|N514H|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTHMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1110|M400T|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGT TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1111|L546V|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVAVKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1112|N605T|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1113|I371T|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTTRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1114|R384G|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPMKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1115|M339F|ARO:3003043|Streptococcus pneumoniae PBP2x conferring resistance to amoxicillin|MEG_5407|Drugs|betalactams|Penicillin_binding_protein|PBP2X|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGKDGIITYEKDR LGNVVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK DFVWRDILYQSNYEPGSPFKVMTLAASIDNNTFPGGEYFNSSELKIADVTIRDWDVNESLTGGGMMTFSQGFAHSSNVGM TLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI SAIYDPNDQTARKSQKEVVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGG YLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPS VKDISPGDLAEELRRNLVQPIVVGTGTKIKESSVEEGTNLAPNQQVILLSDKVEEIPDMYGWKKETAEAFAKWLDIELEF EGSGSVVQKQDVRTNTAIKNIKKITLTLGD >1116|F25I|ARO:3003387|Streptococcus pyogenes folP with mutation conferring resistance to sulfonamides|MEG_2934|Drugs|Sulfonamides|Sulfonamide-resistant_dihydropteroate_synthases|FOLP|RequiresSNPConfirmation|Streptococcus_pyogenes|WP_011017740.1|25|folP_F25I|SULFONAMIDE|SULFONAMIDE|Streptococcus_pyogenes_sulfonamide_resistant_FolP|wt_coherence=TRUE MKIGRFVIEGNAAIMGILNVTPDSISDGGSYTTVQKALDHVEQMIADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIK AIKENYDILISIDTYKTETARAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA QAALDAGVPKNNIWIDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYAL GKGCQIVRVHDVKANQDIVAVLSQLM >1117|A379T|ARO:3003359|Streptomyces cinnamoneus EF-Tu mutants conferring resistance to elfamycin|MEG_7306|Drugs|Elfamycins|EF-Tu_inhibition|TUFAB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDAIPDLNPFTPFDEIDKAPEERQRGITISIAHVEYQTESRHYA HVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTKEHVLLARQSGVPYIVVALNKADMVDDEEIMELVELEVRELL SEYEFDGDNCPVVQVSALKALEGDKEWGEKLLGLMKAVDENIPQPERDVDKPFLMPIEDVFTITGRGTVVTGRIERGVLK VNETVDIIGIKTEKTTTTVTGIEMFRKLLDEGQAGENVGLLLRGIKREDVERGQCIIKPGTVTPHTEFEATAYILSKDEG GRHTPFFNNYRPQFYFRTTDVTGVVTLKEGTEMVMPGDNAEMTVNLIQPVAMEEGLRFTIREGGRTVGAGQVVKINK >1118|R144H|ARO:3005081|Thermus thermophilus uL3 mutations conferring resistance to pleuromutilin antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILRE IRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNHKTPGRVYKGKKMAGHY GAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAAK >1119|R144C|ARO:3005081|Thermus thermophilus uL3 mutations conferring resistance to pleuromutilin antibiotics|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILRE IRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNCKTPGRVYKGKKMAGHY GAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAAK >1120|P462S|ARO:3003305|Ureaplasma urealyticum gyrB conferring resistance to fluoroquinolones|MEG_3240|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNDSNKENKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMIWEIVDNSIDEAMGGFATVVKVIIKKDGVIRVEDDGR GIPVGIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSKNFKVWVNKNYVQHYVEFINGGHAIEPLK IINDKDIKEKGTTIEFIPDFEIMEENEWDELKIMARLKQLAYLNKGVNIEFESEMTNRKEKWHYEGGLKEYIADLNAEKE PLFDAIVYGEEEKEVKVPGHNDQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKLAITRLLNKYAIDKKYL KDTDDKITKEDVSEGLTAIISIKHPNPQYEGQTKKKLGNSEVRPYVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARR RSHEAREATRRKSPFESNSLPGKLADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILSLRGKIINVEKAKIDKIFA NEEIQNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVYIAQPPLYKVSYGKTIK YAYSDQELEKIKSTLLNTKYNIQRYKGLGEMNPDQLWETTMDPKNRLLLKVNIEDAAIADKTFSLLMGDDVTPRKEFIEK NAKYVKNIDA >1121|E502Q|ARO:3003305|Ureaplasma urealyticum gyrB conferring resistance to fluoroquinolones|MEG_3240|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNDSNKENKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMIWEIVDNSIDEAMGGFATVVKVIIKKDGVIRVEDDGR GIPVGIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSKNFKVWVNKNYVQHYVEFINGGHAIEPLK IINDKDIKEKGTTIEFIPDFEIMEENEWDELKIMARLKQLAYLNKGVNIEFESEMTNRKEKWHYEGGLKEYIADLNAEKE PLFDAIVYGEEEKEVKVPGHNDQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKLAITRLLNKYAIDKKYL KDTDDKITKEDVSEGLTAIISIKHPNPQYEGQTKKKLGNSEVRPYVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARR RSHEAREATRRKSPFESNSLPGKLADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFA NEEIQNMITAFGAGIGPEFNIQKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVYIAQPPLYKVSYGKTIK YAYSDQELEKIKSTLLNTKYNIQRYKGLGEMNPDQLWETTMDPKNRLLLKVNIEDAAIADKTFSLLMGDDVTPRKEFIEK NAKYVKNIDA >1122|E87Q|ARO:3003309|Ureaplasma urealyticum parC conferring resistance to fluoroquinolones|MEG_5328|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSVNHQKIINTPLDNIVGESYAKYAKYIIQDRALPDIRDGLKPVQRRILYAMSELGIFYDKPYKKSARTVGEVIGKYHPH GDSSIYQAMVRMSQDWKNNLCLLDMHGNKGSIDGDNAAAMRYTEARLSKIASVMLANLKKDVVKFSPNFDDSEKEPSILP SLFPNLLINGATGIASGYATNIPPHNPNEVFDALIYRIDHPDCSVEKLIEICPAPDFPTGGEIHDLNGCANAHKTGEGKF IIRACIDFKINDNKINQIIISSIPYETNKALIIKEIEDIIYNKEVAGLIEVRDESDAKGISIIIDTKKDINLENVKNYLY KKTNLEISYNTKFIAIVHRTPTLVNLSTYLDAQINHSLDVINKVDLYDLNKILLRIEIVEGLIKCVDLIDEIIKIIRASE SRQDAKNTLIQVFNFTNNQAEAIIMMRLHNLTRTDIFDLKNEWQTLQDEAKTLQERINSLQVRKNYLKQKMIEFKKTFGF ERKTKLFDELVKVEINEDQMIEKQNLNLVISRDGYIKTVSKKSFESSKYDELGLKTNDILFYHNIINSHDKILIITSKAK LINLVAHKITSMRWKDVGEHLNNYVKFDANEKVIAVYIWNEQFKIDEYQLVLASRLNLIKRIELSELDINKNSKQISIMK LNDNDNLISANLIKKGHNQFIIAISKLGLALLFLVHEINCLNRLAKGIKIMKLKPNDEVSAILITPNNGYNVQLFLERGS KCFNISELKLSKRAATPTNLYPITKKVQNVLAAFLVAHENVFYLLDQQQKINPYYLSNPKPTKLDTKISIYENDQMITDV VKDCFLSDEAISDFKKINMYANEFDNEMLKINKNHDDSQLELIDEEEEKK >1123|S83W|ARO:3003309|Ureaplasma urealyticum parC conferring resistance to fluoroquinolones|MEG_5328|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSVNHQKIINTPLDNIVGESYAKYAKYIIQDRALPDIRDGLKPVQRRILYAMSELGIFYDKPYKKSARTVGEVIGKYHPH GDWSIYEAMVRMSQDWKNNLCLLDMHGNKGSIDGDNAAAMRYTEARLSKIASVMLANLKKDVVKFSPNFDDSEKEPSILP SLFPNLLINGATGIASGYATNIPPHNPNEVFDALIYRIDHPDCSVEKLIEICPAPDFPTGGEIHDLNGCANAHKTGEGKF IIRACIDFKINDNKINQIIISSIPYETNKALIIKEIEDIIYNKEVAGLIEVRDESDAKGISIIIDTKKDINLENVKNYLY KKTNLEISYNTKFIAIVHRTPTLVNLSTYLDAQINHSLDVINKVDLYDLNKILLRIEIVEGLIKCVDLIDEIIKIIRASE SRQDAKNTLIQVFNFTNNQAEAIIMMRLHNLTRTDIFDLKNEWQTLQDEAKTLQERINSLQVRKNYLKQKMIEFKKTFGF ERKTKLFDELVKVEINEDQMIEKQNLNLVISRDGYIKTVSKKSFESSKYDELGLKTNDILFYHNIINSHDKILIITSKAK LINLVAHKITSMRWKDVGEHLNNYVKFDANEKVIAVYIWNEQFKIDEYQLVLASRLNLIKRIELSELDINKNSKQISIMK LNDNDNLISANLIKKGHNQFIIAISKLGLALLFLVHEINCLNRLAKGIKIMKLKPNDEVSAILITPNNGYNVQLFLERGS KCFNISELKLSKRAATPTNLYPITKKVQNVLAAFLVAHENVFYLLDQQQKINPYYLSNPKPTKLDTKISIYENDQMITDV VKDCFLSDEAISDFKKINMYANEFDNEMLKINKNHDDSQLELIDEEEEKK >1124|S83L|ARO:3003309|Ureaplasma urealyticum parC conferring resistance to fluoroquinolones|MEG_5328|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSVNHQKIINTPLDNIVGESYAKYAKYIIQDRALPDIRDGLKPVQRRILYAMSELGIFYDKPYKKSARTVGEVIGKYHPH GDLSIYEAMVRMSQDWKNNLCLLDMHGNKGSIDGDNAAAMRYTEARLSKIASVMLANLKKDVVKFSPNFDDSEKEPSILP SLFPNLLINGATGIASGYATNIPPHNPNEVFDALIYRIDHPDCSVEKLIEICPAPDFPTGGEIHDLNGCANAHKTGEGKF IIRACIDFKINDNKINQIIISSIPYETNKALIIKEIEDIIYNKEVAGLIEVRDESDAKGISIIIDTKKDINLENVKNYLY KKTNLEISYNTKFIAIVHRTPTLVNLSTYLDAQINHSLDVINKVDLYDLNKILLRIEIVEGLIKCVDLIDEIIKIIRASE SRQDAKNTLIQVFNFTNNQAEAIIMMRLHNLTRTDIFDLKNEWQTLQDEAKTLQERINSLQVRKNYLKQKMIEFKKTFGF ERKTKLFDELVKVEINEDQMIEKQNLNLVISRDGYIKTVSKKSFESSKYDELGLKTNDILFYHNIINSHDKILIITSKAK LINLVAHKITSMRWKDVGEHLNNYVKFDANEKVIAVYIWNEQFKIDEYQLVLASRLNLIKRIELSELDINKNSKQISIMK LNDNDNLISANLIKKGHNQFIIAISKLGLALLFLVHEINCLNRLAKGIKIMKLKPNDEVSAILITPNNGYNVQLFLERGS KCFNISELKLSKRAATPTNLYPITKKVQNVLAAFLVAHENVFYLLDQQQKINPYYLSNPKPTKLDTKISIYENDQMITDV VKDCFLSDEAISDFKKINMYANEFDNEMLKINKNHDDSQLELIDEEEEKK >1125|S84P|ARO:3003309|Ureaplasma urealyticum parC conferring resistance to fluoroquinolones|MEG_5328|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|PARC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSVNHQKIINTPLDNIVGESYAKYAKYIIQDRALPDIRDGLKPVQRRILYAMSELGIFYDKPYKKSARTVGEVIGKYHPH GDSPIYEAMVRMSQDWKNNLCLLDMHGNKGSIDGDNAAAMRYTEARLSKIASVMLANLKKDVVKFSPNFDDSEKEPSILP SLFPNLLINGATGIASGYATNIPPHNPNEVFDALIYRIDHPDCSVEKLIEICPAPDFPTGGEIHDLNGCANAHKTGEGKF IIRACIDFKINDNKINQIIISSIPYETNKALIIKEIEDIIYNKEVAGLIEVRDESDAKGISIIIDTKKDINLENVKNYLY KKTNLEISYNTKFIAIVHRTPTLVNLSTYLDAQINHSLDVINKVDLYDLNKILLRIEIVEGLIKCVDLIDEIIKIIRASE SRQDAKNTLIQVFNFTNNQAEAIIMMRLHNLTRTDIFDLKNEWQTLQDEAKTLQERINSLQVRKNYLKQKMIEFKKTFGF ERKTKLFDELVKVEINEDQMIEKQNLNLVISRDGYIKTVSKKSFESSKYDELGLKTNDILFYHNIINSHDKILIITSKAK LINLVAHKITSMRWKDVGEHLNNYVKFDANEKVIAVYIWNEQFKIDEYQLVLASRLNLIKRIELSELDINKNSKQISIMK LNDNDNLISANLIKKGHNQFIIAISKLGLALLFLVHEINCLNRLAKGIKIMKLKPNDEVSAILITPNNGYNVQLFLERGS KCFNISELKLSKRAATPTNLYPITKKVQNVLAAFLVAHENVFYLLDQQQKINPYYLSNPKPTKLDTKISIYENDQMITDV VKDCFLSDEAISDFKKINMYANEFDNEMLKINKNHDDSQLELIDEEEEKK >1126|E233STOP|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYL* >1127|Q44STOP|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|44|nfsA_Q44STOP|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFL* >1128|K141STOP|ARO:3003751|Escherichia coli nfsA mutations conferring resistance to nitrofurantoin|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVT* >1129|R279STOP|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDV* >1130|E420STOP|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVV* >1131|W289STOP|ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNP* >1132|C52STOP|ARO:3003470|Mycobacterium tuberculosis gidB mutation conferring resistance to streptomycin|MEG_3135|Drugs|Aminoglycosides|Aminoglycoside-resistant_gidB|GIDB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSPIEPAASAIFGPRLGLARRYAEALAGPGVERGLVGPREVGRLWDRHLLN* >1133|Q351STOP|ARO:3003451|Mycobacterium tuberculosis iniC mutant conferring resistance to ethambutol|MEG_3432|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol-resistant_mutant|INIC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALAGTLKAGKSTLVNALVGDDIAPTDATEATRI VTWFRHGPTPRVTANHRGGRRANVPITRRGGLSFDLRRINPAELIDLEVEWPAEELIDATIVDTPGTSSLACDASERTLR LLVPADGVPRVDAVVFLLRTLNAADVALLKQIGGLVGGSVGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQM GICQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRRDSPLPVDAGIRAQLLERFGMFGIRMSIA VLAAGVTDSTGLAAELLERSGLVALRNVID* >1134|Y304STOP|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSS* >1135|W91STOP|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPW* >1136|E506STOP|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGW* >1137|E454STOP|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEA* >1138|Q10STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDV* >1139|Y103STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGA* >1140|W68STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSS* >1141|W119STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLN* >1142|Q141STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVR* >1143|S88STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDT* >1144|Y41STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAAD* >1145|Y99STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGA* >1146|Q122STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLR* >1147|Q513STOP|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRK* >1148|S522STOP|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDE* >1149|G76STOP|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEH* >1150|W83STOP|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DE* >1151|W98STOP|ARO:3004153|Mycobacterium tuberculosis thyA with mutation conferring resistance to para-aminosalicylic acid|MEG_7250|Drugs|Mycobacterium_tuberculosis-specific_Drug|Para-aminosalicylic_acid_resistant_mutant|THYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFLRGDSNIGWLHEHGVTIW DEWASDTGELGPIYGVQ* >1152|Q22STOP|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQ* >1153|R18STOP|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLA* >1154|R3STOP|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MA* >1155|Q184STOP|ARO:3003445|Mycobacterium tuberculosis tlyA mutations conferring resistance to aminoglycosides|MEG_7258|Drugs|Aminoglycosides|Aminoglycoside-resistant_arabinosyltransferase|TLYA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLVGALEAFAIA VAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISL ATVLPALVGCASRDADIVPLVKP* >1156|W355STOP|ARO:3003901|Staphylococcus aureus GlpT with mutation conferring resistance to fosfomycin|MEG_3143|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYILIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNA* >1157|L42STOP|ARO:3003776|Staphylococcus aureus murA with mutation conferring resistance to fosfomycin|MEG_4094|Drugs|Fosfomycin|Fosfomycin_target_mutation|MURA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSK* >1158|Y314STOP|ARO:3003902|Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin|MEG_7329|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001008722.1|314|uhpT_Y314STOP|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_UhpT|wt_coherence=TRUE MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWG* >1159|W228STOP|ARO:3003902|Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin|MEG_7329|Drugs|Fosfomycin|Fosfomycin_target_mutation|UHPT|RequiresSNPConfirmation|Staphylococcus_aureus|WP_001008722.1|228|uhpT_W228STOP|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_UhpT|wt_coherence=TRUE MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEI* >1160|F330S|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPSGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1161|S22C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFACARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1162|N296H|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGAHSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1163|A454T|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVATLVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1164|L402V|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GVRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1165|Y319S|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNSF RWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1166|Y147STOP|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEG* >1167|H281P|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKPFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1168|N379D|ARO:3003458|Mycobacterium tuberculosis ethA with mutation conferring resistance to ethionamide|MEG_2866|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethionamide-resistant_mutant|ETHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPDMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1169|D94H|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDASIYHSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >1170|E501D|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDDAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1171|N499T|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVETDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1172|T162S|ARO:3003393|Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid|MEG_3429|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|INHA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTE AIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNW MSVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK TVCALLSDWLPATTGDIIYADGGAHTQLL >1173|I317V|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGVEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1174|W191R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQREPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1175|D63G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPGYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1176|Y34D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDDLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1177|L4S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRASIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1178|D49N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKNFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1179|D49G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKGFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1180|I5T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALTIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1181|H51R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFRIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1182|H57R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDRFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1183|F58S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHSSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1184|I6T|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALITVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1185|P62S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTSDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1186|D8N|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVNVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1187|D8H|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVHVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1188|D8E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVEVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1189|G108STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFE* >1190|C138R|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHRVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1191|V139G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCGRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1192|A146E|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDEVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1193|A146V|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDVVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1194|L151S|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGSATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1195|S164STOP|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGV* >1196|V180A|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASAELVCSS >1197|V180G|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASGELVCSS >1198|I1106T|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENTPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1199|Q975H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAHEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1200|G836S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHSESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1201|H835R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPRGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1202|R827H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVHDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1203|L731P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIIPSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1204|F503S|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPSGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1205|I480V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPV ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1206|P45L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVLGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1207|S450W|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLWALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1208|H445R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTRKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1209|H445Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTYKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1210|D435V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMVQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1211|D435G|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMGQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1212|M434I|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFIDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1213|Q432P|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSPFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1214|H445D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTDKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1215|A412V|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRVEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >1216|A381V|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMVDSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >1217|A440T|ARO:3004721|Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide|MEG_6142|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|RPSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVV SVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD LQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSEL SWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGL VHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAET NEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAETAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGS A >1218|A118S;T82A|ARO:3003995|Clostridioides difficile gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHG DAAVYYAMVRMAQDFSTRALLVDGHGNFGSVDGDSPASMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVK VRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYK HSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKT GQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDE RRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNK GRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGL RDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRT NIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSI AKINIEEE >1219|I548M;R505K|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQLSQFMDQTNPLSELTHKRKLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLMNSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >1220|L487F;H502Y|ARO:3004563|Clostridioides difficile rpoB with mutation conferring resistance to rifampicin|MEG_6095|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MVHPVQVGKRTRMSFSRLKEIGHMPNLIEVQLDSYNWFLKEGLQEVFDDINPIQDYTANLNLEFVGYKLDMDNIKYSVEE CKERDATYAAPLKVKVRLINKETGEVKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDLSVDKTGKNLFSS TVIPNRGAWLEYETDSNNVIYVRIDKTRKLPITILIRAMGYGTDAEITNFFGEDERLKATIEKDNTKTHEEALLEIYKRL RPGEPPTVDSAQSLIESLFFDAKRYDLSRVGRYKFNKKLSLHLRIANQIAAQDVVNPDTGEILIQKGEKINREKAVEIQQ CGINVVDIQIEDIVLRVIGNNFVDIRSFIDFDIDDLNIKESVHYPTLKKILDNYSDEESIKEQIRKNIHELIPKHIVRDD MYATISYELGLAYGVGHTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKE FFGSSQFSQFMDQTNPLSELTYKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYARVNQY GFIETPYRKVDKENKRVTNEIVYMTADEEDEYLIGRANEPIDENGNFIDNKITVRDKEDVIVVPGQDVDYMDVSSRQLVS VATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAAVDSGVLPKARNAGVVSYVCANEVRVKRDSDGGT DIYRLLKFQRSNQCTCINQRPIVEKGEVVKKGTVLADGPSTDLGEIALGKNIRMGFTTWEGYNYEDAMLISEELVKKDVF TSIHLEEYESEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGE KAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFL PDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASKLGWHVATPVFDGATEEDILECLKKAGYREDGKTILYDGRTGEEFN RPVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRV KTYEAIVKGENIPEPGIPESFKVLIKELQALCLDVKVLNDNKEEIKLKESVDEEMEKLDVNIEGKEDSTDLPQEQNDDYN TEQEENNDSENDSDEDLDLDYEDLTLDDLQSDLEIDDFNDEH >1221|E448K;G33R|ARO:3003889|Escherichia coli GlpT with mutation conferring resistance to fosfomycin|MEG_3144|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLRIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSK FIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELT AKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGN RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAA SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG >1222|E448K;G302D|ARO:3003889|Escherichia coli GlpT with mutation conferring resistance to fosfomycin|MEG_3144|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSK FIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELT AKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYADIPGTLLCGWMSDKVFRGN RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAA SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG >1223|E448K;Q444E;E443Q;L297F|ARO:3003889|Escherichia coli GlpT with mutation conferring resistance to fosfomycin|MEG_3144|Drugs|Fosfomycin|Fosfomycin_target_mutation|GLPT|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSK FIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELT AKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGN RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAA SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRNGG >1224|S83L;D87Y|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDLAVYYTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >1225|S83L;D87N|ARO:3003294|Escherichia coli gyrA conferring resistance to fluoroquinolones|MEG_3187|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDLAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE >1226|A314G;Y322C|ARO:3003326|Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol|MEG_2710|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAPLISLTPVDFT ATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFAN FVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYF RCFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNN GLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCW ATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPLGGVNPVGFTPNGVPEHTVAE AIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAA GKIAGNSVLHGYTPGQTVVLEYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGIT DLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP >1227|I161V;G324R|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP VIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATRIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1228|Q254P;S266R|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACPKWPRRMRKMFLRLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1229|R239Q;S266R|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVQW KNVLRQAAVYSACQKWPRRMRKMFLRLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1230|Q246R;L446P|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRRAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDEPPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1231|S266R;P454L|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLRLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTLWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1232|S266R;M373T|ARO:3005105;ARO:3005106|Mycobacterium tuberculosis ethA mutations conferring resistance to isoniazid;Mycobacterium tuberculosis ethA mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKP ILEYVKSTAAMYGIDRHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDEGYSPRFAGSEDFVGP IIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALADSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRW KNVLRQAAVYSACQKWPRRMRKMFLRLIQRQLPEGYDVRKHFGPHYNPWDQRLCLVPNGDLFRAIRHGKVEVVTDTIERF TATGIRLNSGRELPADIIITATGLNLQLFGGATATIDGQQVDITTTMAYKGMTLSGIPNMAYTVGYTNASWTLKADLVSE FVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDELPKQGSRTPWRLNQNYLRDIRLIRRGKIDDEGLRF AKRPAPVGV >1233|A90V;D94G|ARO:3003295|Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones|MEG_3180|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAET MGNYHPHGDVSIYGSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKR DAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDA LDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFV CSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDF DSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKG VRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN >1234|R485C;T539N|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCCSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNNEVQAIITALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1235|N538D;T546M|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKDTEVQAIIMALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1236|R485C;T546M|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCCSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIIMALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1237|N538T;T546M|ARO:3003459|Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolones|MEG_3243|Drugs|Fluoroquinolones|Fluoroquinolone-resistant_DNA_topoisomerases|GYRB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGKNEARRSALAPDHGTVVCDPLRRLNRMHATPEESIRIVAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERG LHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLH GVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLN KGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGK GTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVK VSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGK LADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKTTEVQAIIMALGTGIHDEFDIGK LRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKI NKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV >1238|G279V;L436P|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAVPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTPLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1239|V431A;G490S|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLAPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRSGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1240|P92S;S315T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWSADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1241|S315T;G466R|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASRLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1242|S315T;V581G|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDGESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1243|S211G;S315T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYGGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1244|C20R;S315T|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGRPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1245|N596S;Y597H|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRSHLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1246|M126I;R496L|ARO:3003392|Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid|MEG_3446|Drugs|Mycobacterium_tuberculosis-specific_Drug|Isoniazid-resistant_mutant|KATG|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGIQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGLIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1247|S134S;T308P|ARO:3005102|Mycobacterium tuberculosis katG mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGPGKDAITSGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1248|T275A;S315T|ARO:3005102|Mycobacterium tuberculosis katG mutations conferring resistance to prothionamide|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDI EEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLS WADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPD PMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKAHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVV WTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEH PEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAA SSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAG HNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKR LPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKF VQDFVAAWDKVMNLDRFDVR >1249|L251R;A254G;T270I|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHIRDTGDGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1250|T270I;I297T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVGANTSDDGYTLTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1251|A244T;G288W;V303G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGATLVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVWANTSDDGYILTMARGSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1252|I297L;W326R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYLLTMARVSEHAGYMANYYRWFGTP EAPFGRYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1253|T270I;Y296H;G308D;G325S|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVGANTSDDGHILTMARVSEHADYMANYYRWFGTP EAPFSWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1254|A247P;I297L;W326R|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVPLHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYLLTMARVSEHAGYMANYYRWFGTP EAPFGRYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1255|V287F;Y309N|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFFGANTSDDGYILTMARVSEHAGNMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1256|Y296S;R302G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGSILTMAGVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1257|A247P;T270I;I297T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVPLHILDTADGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVGANTSDDGYTLTMARVSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1258|G272S;H285Y;M300R;A307T|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGSLDTLVIAVLVWWYFVGANTSDDGYILTRARVSEHTGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1259|G288W;V303G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVWANTSDDGYILTMARGSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1260|T270I;G288W;V303G|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSIGGLDTLVIAVLVWWHFVWANTSDDGYILTMARGSEHAGYMANYYRWFGTP EAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1261|G288V;M310K;Y327N|ARO:3003327|Mycobacterium tuberculosis embC mutant conferring resistance to ethambutol|MEG_2712|Drugs|Mycobacterium_tuberculosis-specific_Drug|Ethambutol_resistant_arabinosyltransferase|EMBC|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVAT DLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAH ADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVAL TGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVVANTSDDGYILTMARVSEHAGYKANYYRWFGTP EAPFGWNYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEP IIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAA TVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGT AAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGW WYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEV VSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVM ERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRA PLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIAL TPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLM RATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG >1262|Q10P;Y99D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVPNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGADTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1263|A25E;A26G;A28D|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGEGLDRAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1264|D63Y;T142K|ARO:3003394|Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide|MEG_5803|Drugs|Mycobacterium_tuberculosis-specific_Drug|Pyrazinamide-resistant_mutant|PNCA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPYYSSSWPPHCVSGTPGAD FHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQKAEDAVRNGLATRVLVDLT AGVSADTTVAALEEMRTASVELVCSS >1265|S531L;S622A|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEELRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGAGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1266|H526S;M515V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVVGVVSDEIVYLSADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1267|H526S;P535H|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLSADEEDRHVHAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1268|H526Y;E541G|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLYADEEDRHVVAQANSGIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1269|D516Y;L511R|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDYVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1270|-S512;-Q513;-F514;H526Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRDGVVSDEIVYLQADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAGEVE YVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEESGV IEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGH NYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKVTPK GETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRH GNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEAQPN AIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPY SMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQ SLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1271|D516E;S522L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDEVVSDELVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1272|S531L;H526C|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLCADEELRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1273|L511R;D516V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDVVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1274|L511P;M515I|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYPKVVIGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1275|L524W;T525P;H526Q;-527K|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVWPQAKDEEDRHVVAQANSPIDADGRFVEPRVLVRRKA GEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMP WEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGK VTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKL AGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLE AQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARS TGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLL KELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1276|Q513H;-514F;-515M;-516D|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKHVFDMGDVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRR KAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVV AEESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAI MPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILV GKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGD KLAGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDEL LEAQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHA RSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKV LLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1277|-519N;S522L;S531L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSNDELVYLTADEELRHVVAQANSPIDADGRFVEPRVLVRRKA GEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMP WEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGK VTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKL AGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLE AQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARS TGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLL KELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1278|H526D;S531|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLDADEERHVVAQANSPIDADGRFVEPRVLVRRKAGE VEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEES GVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPWE GHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKVT PKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAG RHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEAQ PNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTG PYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKE LQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1279|L511P;S512T;D516V|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYPTVVDVVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1280|T516I;G523W;D525Y|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDIVVSDEIWYYTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1281|H526D;E541G;S553A|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLDADEEDRHVVAQANSGIDADGRFVEPRALVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1282|H526P;K527Q|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLPQDEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1283|E562G;P564L|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG EGELVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEE SGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKV TPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLA GRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARST GPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1284|-515M;-516D;-517Q;-518N|ARO:3003283|Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin|MEG_6090|Drugs|Rifampin|Rifampin-resistant_beta-subunit_of_RNA_polymerase_RpoB|RPOB|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGL EEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTF IINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGE PITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTT QDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDMGDVQVNSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVR RKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVV VAEESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVA IMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDIL VGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDG DKLAGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDE LLEAQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIH ARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFK VLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA >1285|G120P;A121P|ARO:3000464|Neisseria gonorrhoeae porin PIB (por)|MEG_5808|Drugs|Multi-drug_resistance|MDR_mutant_porin_proteins|POR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTKGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQ GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTPPNVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG FSGSVQYAPKDNSGSNGESYHVGLNYRNNGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNAL YVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSAL VSAGWLQEGKGADKIVSTASAVVLRHKF >1286|G120R;A121H|ARO:3000464|Neisseria gonorrhoeae porin PIB (por)|MEG_5808|Drugs|Multi-drug_resistance|MDR_mutant_porin_proteins|POR|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTKGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQ GASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTRHNVNAWESGKFTGNVLEISGMAQREHRYLSVRYDSPEFAG FSGSVQYAPKDNSGSNGESYHVGLNYRNNGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNAL YVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSAL VSAGWLQEGKGADKIVSTASAVVLRHKF >1287|T83I;D87G|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPH GDIAVYGTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >1288|T83I;D87H|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPH GDIAVYHTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >1289|T83I;D87N|ARO:3003684|Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MGELAKEILPVNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPH GDIAVYNTIVRMAQPFSLRYMLVDGQGNFGSVDGDNAAAMRYTEVRMAKLAHELLADLEKETVDWVPNYDGTEQIPAVMP TKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLTVDELMQYIPGPDFPTAGIINGRAGIIEAYRTGRGRI YIRARAVVEEMEKGGGREQIIITELPYQLNKARLIEKIAELVKEKKIEGISELRDESDKDGMRVVIELRRGEVGEVVLNN LYAQTQLQSVFGINVVALVDGQPRTLNLKDMLEVFVRHRREVVTRRTVYELRKARERGHILEGQAVALSNIDPVIELIKS SPTPAEAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDGKYYLSPEQAQAILELRLHRLTGLEHEKLLSEYQ EILNLIGELIRILTNPARLMEVIREELEAVKAEFGDARRTEIVASQVDLTIADLITEEDRVVTISHGGYAKSQPLAAYQA QRRGGKGKSATGMKDEDYIEHLLVANSHATLLLFSSKGKVYWLRTFEIPEASRTARGRPLVNLLPLDEGERITAMLQIDL EALQQNGGADDDLDEAEGAVLEGEVVEAAEVEEVEGETAELVAEPTGAYIFMATAFGTVKKTPLVQFSRPRSSGLIALKL EEGDTLIAAAITDGAKEVMLFSSAGKVIRFAESVVRIMGRNARGVRGMRLGKGQQLISMLIPESGAQILTASERGFGKRT PLSKFPRRGRGGQGVIAMVTNERNGALIAAVQVQEGEEIMLISDQGTLVRTRVDEVSLSGRNTQGVTLIKLASDEVLVGL ERVQEPSGGDDEDLPEGEEAAESLGESAESESEPAAEAEGNEE >1290|G452C;R659L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGCMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLLSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1291|A70V;A160V;H457Y|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTVAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAV PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELYLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1292|T387I;E449K|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=FALSE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGITLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVKIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1293|D189V;L430S|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNVLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKSQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1294|F652S;Y654N|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMSGNATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1295|V90I;H457Q;L461K;A655V|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTIEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELQLDIKVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYVTSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1296|A67T;P406L|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSATTTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPELVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1297|H457Y;S416F|ARO:3003735|Staphylococcus aureus fusA with mutation conferring resistance to fusidic acid|MEG_3065|Drugs|Fusidic_acid|Fusidic_acid-resistant_mutation|FUSA|RequiresSNPConfirmation|NA|NA|NA|NA|NA|NA|NA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKFKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELYLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1298|A12S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000019358.1|12|soxS_A12S|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxS|wt_coherence=TRUE MSHQKIIQDLISWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDL GYVSQQTFSRVFRRQFDRTPSDYRHRL >1299|R231C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|231|tufA_R231C|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGCVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1300|R231V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|231|tufA_R231V|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGVVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1301|R234F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|234|tufA_R234F|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVEFGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1302|R234S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|234|tufA_R234S|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVESGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1303|R334C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|334|tufA_R334C|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFCTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1304|T335A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000031783.1|335|tufA_T335A|POLYKETIDE|PULVOMYCIN|Escherichia_pulvomycin_resistant_TufA|wt_coherence=TRUE MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHV DCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ YDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVG EEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRH TPFFKGYRPQFYFRATDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG >1305|Y421C|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000072047.1|421|gyrB_Y421C|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELCLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1306|R438L|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000072047.1|438|gyrB_R438L|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNLKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1307|S464F|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000072047.1|464|gyrB_S464F|QUINOLONE|CIPROFLOXACIN|Salmonella_ciprofloxacin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSFQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1308|S464T|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000072047.1|464|gyrB_S464T|QUINOLONE|CIPROFLOXACIN|Salmonella_ciprofloxacin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSTQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1309|S464Y|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000072047.1|464|gyrB_S464Y|QUINOLONE|CIPROFLOXACIN|Salmonella_ciprofloxacin_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSYQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEK EQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFE QALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1310|D426N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000072067.1|426|gyrB_D426N|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGNSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1311|K447E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000072067.1|447|gyrB_K447E|QUINOLONE|NALIDIXIC_ACID|Escherichia_nalidixic_acid_resistant_GyrB|wt_coherence=TRUE MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLEGKILNVEKARFDKMLSSQEVATLITALGCGIGR DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA NIDI >1312|P114H|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|114|fusA_P114H|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEHQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1313|A160V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|160|fusA_A160V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAV PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1314|D189G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|189|fusA_D189G|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNGLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1315|D189V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|189|fusA_D189V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNVLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1316|E233Q|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|233|fusA_E233Q|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDQEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1317|D373N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|373|fusA_D373N|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGNIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1318|T385N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|385|fusA_T385N|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGNGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1319|D387I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|387|fusA_D387I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGITLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1320|S416F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|416|fusA_S416F|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKFKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1321|L430S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|430|fusA_L430S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKSQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1322|H438N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|438|fusA_H438N|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFNAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1323|E444K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|444|fusA_E444K|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEKTGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1324|E444V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|444|fusA_E444V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEVTGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1325|I449K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|449|fusA_I449K|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVKIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1326|L456K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|456|fusA_L456K|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGEKHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1327|D463G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|463|fusA_D463G|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVGRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1328|C473S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|473|fusA_C473S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVESNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1329|P478S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|478|fusA_P478S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGASMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1330|G556S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|556|fusA_G556S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLASYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1331|V607I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|607|fusA_V607I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKITIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1332|G617D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|617|fusA_G617D|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMDDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1333|M651I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|651|fusA_M651I|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEIFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1334|F652S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|652|fusA_F652S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMSGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1335|Y654N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|654|fusA_Y654N|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGNATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1336|A655E|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|655|fusA_A655E|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYETSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1337|A655P|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|655|fusA_A655P|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYPTSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1338|A655V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|655|fusA_A655V|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYVTSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1339|T656K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|656|fusA_T656K|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYAKSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1340|R659C|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|659|fusA_R659C|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLCSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1341|R659H|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|659|fusA_R659H|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLHSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1342|R659L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|659|fusA_R659L|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLLSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1343|R659S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|659|fusA_R659S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLSSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1344|G664S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000090315.1|664|fusA_G664S|FUSIDIC_ACID|FUSIDIC_ACID|Staphylococcus_aureus_fusidic_acid_resistant_FusA|wt_coherence=TRUE MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNII DTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSEL KEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDP YVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILES MEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMV SYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLI DVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQ VVNAYVPLSEMFGYATSLRSNTQSRGTYTMYFDHYAEVPKSIAEDIIKKNKGE >1345|R45C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000101737.1|45|acrR_R45C|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_AcrR|wt_coherence=TRUE MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTCGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAK FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE >1346|S569A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000138348.1|569|pbp2_S569A|BETA-LACTAM|CEPHALOSPORIN|Staphylococcus_aureus_cephalosporin_resistant_Pbp2|wt_coherence=TRUE MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWKAPAFTEAKLQDPIPAKIYDK NGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLS QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY DHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTAEERQNIDTNQDSEYNSYVNFVKSELMNNKEFKDEN LGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSL KPFLAYGPAIENMKWATNHAIQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAA KLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEYDHTSHKAMSDYTAYMLAEML KGTFKPYGAAYGHGVAGVNMGAKTGTGTYGAETYSQYNLPDNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQ QEYPQFLYENVMSKISSRDGEDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQSRNSG GLTGIFN >1347|G139R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000160212.1|139|rplC_G139R|OXAZOLIDINONE|LINEZOLID|Staphylococcus_aureus_linezolid_resistant_RplC|wt_coherence=TRUE MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKA DAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRRPMSHGSHFHRAPGSVGMASDA SRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK >1348|S145DEL|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000160212.1|145|rplC_S145DEL|OXAZOLIDINONE|LINEZOLID|Staphylococcus_aureus_linezolid_resistant_RplC|wt_coherence=TRUE MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKA DAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGDELHFHRAPGSVGMAS DASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK >1349|G152D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000160212.1|152|rplC_G152D|OXAZOLIDINONE|LINEZOLID|Staphylococcus_aureus_linezolid_resistant_RplC|wt_coherence=TRUE MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKA DAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPDSVGMASDA SRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK >1350|G155R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000160212.1|155|rplC_G155R|OXAZOLIDINONE|LINEZOLID|Staphylococcus_aureus_linezolid_resistant_RplC|wt_coherence=TRUE MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKA DAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVRMASDA SRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK >1351|M169L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000160212.1|169|rplC_M169L|OXAZOLIDINONE|LINEZOLID|Staphylococcus_aureus_linezolid_resistant_RplC|wt_coherence=TRUE MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKA DAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDA SRVFKGQKLPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK >1352|L21V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|21|dfrB_L21V|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQVPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1353|H31N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|31|dfrB_H31N|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKNVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1354|L41F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|41|dfrB_L41F|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTFVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1355|N60I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|60|dfrB_N60I|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRIVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1356|F99I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|99|dfrB_F99I|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILIEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1357|F99S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|99|dfrB_F99S|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILSEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1358|F99Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|99|dfrB_F99Y|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK >1359|H150R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000175752.1|150|dfrB_H150R|TRIMETHOPRIM|TRIMETHOPRIM|Staphylococcus_aureus_trimethoprim_resistant_DfrB|wt_coherence=TRUE MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSI EDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPRTFLHLIRKK >1360|M438I|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|438|parE_M438I|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIIPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1361|E454G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|454|parE_E454G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDGVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1362|S458P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|458|parE_S458P|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLAPQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1363|H462Y|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|462|parE_H462Y|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVYDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1364|A499T|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|499|parE_A499T|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHITTLLCALFVRHFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1365|V514G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|514|parE_V514G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALGKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1366|V521F|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000195318.1|521|parE_V521F|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDGLNDYLGEAVNGLPTLPEKPFIG NFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVRHFRALVKNGHVYFALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGDLADLDV >1367|S84F|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_000202259.1|84|parC_S84F|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_ParC|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDFACYEAMVLMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >1368|S84W|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_000202259.1|84|parC_S84W|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_ParC|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDWACYEAMVLMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >1369|E88K|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_000202259.1|88|parC_E88K|QUINOLONE|QUINOLONE|Acinetobacter_baumannii_quinolone_resistant_ParC|wt_coherence=TRUE MTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHP HGDSACYKAMVLMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPIT LPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGR GSYRMRAVYTIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNRIDAEAVMSHLF ATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREE DQPKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIIGELKEDAKKFGDER RSPIVARAEAVQIKEQDLMPAETVTVVLSEAGWVRAAKGADVDAENLNYRAGDQYLSHAVGKTNQRVYFLDETGRSYALP ISNLPSARGLGDPLSSKLSPASGVSFIQVYLDDDESELIAASSAGYGFKTQTKQLDTNAKAGKTFLTVPDKAKALPLISA QNMTHLAVLSSAGRLLILDLAELPNLNKGKGNKLIQLEGKEQILSMTTLNLDEIIQVVAGQQHLKLKGDDLQKYMGKRAS KGQLLPRGYQKANKLLIQR >1370|A515V|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_000227936.1|515|ftsI_A515V|BETA-LACTAM|CARBAPENEM|Acinetobacter_baumannii_carbapenem_resistant_FtsI|wt_coherence=TRUE MVDKRTKQTRKKQQSISEKPSLAFDMWRFYLLWAVVLLCFVVLIARAFYVQVINKDFLQNKANANILRTERIEAMRGVIS DRHGVPLAISSPIMKIVIDPRDYFETKHLYDQITAELKQDPNNRKLKRQLPDKNLNLDELADVVGVDRADLKKQMNARPR SRYLVLKKEVPPQQADLIMKGNFQGVYAEKTYKRYYPQPQPNAQIIGLTNSEGQGIEGLEMQLNKQLSGVDGEQKIIRDK RGNRLKVSEVIREGEPGENITLSIDSRLQYIMYRELTAAGVANNARSATAIAVDVKTGEILAMTSWPSYNPNDKNGLSNK DAMRNRGAIDMFEPGSTMKPFTISAALETGQYTPNTIVNTSPGSMRLGWHTIRDTHNYGALTVSGVIIKSSNVGSAKIAL SLPKETLPSFFNRVGFGKRSAVRFPGESSGLVLPVNKLNSSQIGTMAYGYGLNATILQLAQGYAMLANHGVKMPLSLHKL DQPPKGEQVLNPKIADQVLLMLEQVTMPGGTAKQVNIPGYRVGGKTGTAHKLRADGKGYSNNEYRALFAGVAPISDPRLA VIVVVENPQGRYYGGLVAAPVFARIMQESLRLMNVPLDKPLNTPENPIRR >1371|I572F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000263098.1|572|rpoB_I572F|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLFNSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >1372|I572L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000263098.1|572|rpoB_I572L|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLLNSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >1373|I572N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000263098.1|572|rpoB_I572N|RIFAMYCIN|RIFAMYCIN|Escherichia_rifamycin_resistant_RpoB|wt_coherence=TRUE MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP IETPEGPNIGLNNSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE >1374|D396N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000357259.1|396|murA_D396N|FOSFOMYCIN|FOSFOMYCIN|Escherichia_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHINRGYE RIEDKLRALGANIERVKGE >1375|V65A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000358006.1|65|murA_V65A|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADATYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1376|G257D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000358006.1|257|murA_G257D|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRDAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1377|Q362R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000358006.1|362|murA_Q362R|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSRLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR GYVDLHGKLKQLGADIERIND >1378|T396N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000358006.1|396|murA_T396N|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_MurA|wt_coherence=TRUE MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELNHLDR GYVDLHGKLKQLGADIERIND >1379|L64R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000378442.1|64|emrR_L64R|QUINOLONE|NITROXOLINE|Escherichia_nitroxoline_resistant_EmrR|wt_coherence=TRUE MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITRESQENHSIQPSELSCA LGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS RLDQMEQDGVVLEAMS >1380|L113P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000378442.1|113|emrR_L113P|QUINOLONE|NITROXOLINE|Escherichia_nitroxoline_resistant_EmrR|wt_coherence=TRUE MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA LGSSRTNATRIADELEKRGWIERRESDNDRRCPHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS RLDQMEQDGVVLEAMS >1381|H67Q|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000384706.1|67|ileS_H67Q|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGQALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1382|F563L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000384706.1|563|ileS_F563L|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWLNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1383|G593V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000384706.1|593|ileS_G593V|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWFNSSITTSVATRGVSPYKFLLSHGFVMDGEVKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1384|R816C|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000384706.1|816|ileS_R816C|MUPIROCIN|MUPIROCIN|Staphylococcus_aureus_mupirocin_resistant_IleS|wt_coherence=TRUE MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRY KTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSN VAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAG TGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRT KKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETV NHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYR GWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQ TSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFY LDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRT FMNLRDDVNRALETACNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEH ADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV >1385|R20H|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000412428.1|20|soxR_R20H|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxR|wt_coherence=TRUE MEKKLPRIKALLTPGEVAKHSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVL PEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN >1386|G121D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000412428.1|121|soxR_G121D|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_SoxR|wt_coherence=TRUE MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVL PEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIDCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN >1387|G15R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000697899.1|15|pmrA_G15R|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrA|wt_coherence=TRUE MKILIVEDDTLLLQRLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA RDTLNDRITGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVATEES >1388|G53E|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000697899.1|53|pmrA_G53E|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrA|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLELPDEDGLHFLTRIRQKKYTLPVLILTA RDTLNDRITGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVATEES >1389|G53R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000697899.1|53|pmrA_G53R|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrA|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLRLPDEDGLHFLTRIRQKKYTLPVLILTA RDTLNDRITGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVATEES >1390|R81C|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000697899.1|81|pmrA_R81C|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrA|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA CDTLNDRITGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVATEES >1391|R81H|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_000697899.1|81|pmrA_R81H|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrA|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA HDTLNDRITGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVATEES >1392|F28I|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|28|folP_F28I|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSISDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >1393|F28L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000764731.1|28|folP_F28L|SULFONAMIDE|SULFONAMIDE|Escherichia_sulfonamide_resistant_FolP|wt_coherence=TRUE MKLFAQGTSLDLSHPHVMGILNVTPDSLSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIP VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE >1394|D73G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|73|gyrA_D73G|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGGVMGKYHP HGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1395|G82C|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|82|gyrA_G82C|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HCDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1396|S84A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|84|gyrA_S84A|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDASIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1397|S84L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|84|gyrA_S84L|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDLSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1398|S84V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|84|gyrA_S84V|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDVSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1399|S85P|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|85|gyrA_S85P|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSPIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1400|E88G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|88|gyrA_E88G|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYGAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1401|E88K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|88|gyrA_E88K|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYKAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1402|E88L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|88|gyrA_E88L|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYLAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1403|E88R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|88|gyrA_E88R|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYRAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1404|G106D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000819084.1|106|gyrA_G106D|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrA|wt_coherence=TRUE MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP HGDSSIYEAMVRMAQDFSYRYPLVDDQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGS IQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRE SDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRF GDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGK IAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTE NGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGD DQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDI QQSSDEE >1405|S3N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|3|marR_S3N|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKNTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1406|E31STOP|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|31|marR_E31STOP|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLN* >1407|V45E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|45|marR_V45E|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKELCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1408|I49S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|49|marR_I49S|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSSRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1409|A70T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|70|marR_A70T|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGTLTRMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1410|R73C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|73|marR_R73C|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTCMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1411|R73S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|73|marR_R73S|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTSMLDRLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1412|R77C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|77|marR_R77C|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDCLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1413|R77L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|77|marR_R77L|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDLLVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1414|L78M|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|78|marR_L78M|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRMVC KGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1415|R94H|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|94|marR_R94H|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKHGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1416|R94S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|94|marR_R94S|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKSGVLVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1417|V96E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_000843414.1|96|marR_V96E|MULTIDRUG|AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE|Escherichia_ampicillin/chloramphenicol/quinolone/rifampin/tetracycline_resistant_MarR|wt_coherence=TRUE MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC KGWVERLPNPNDKRGELVKLTTGGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP >1418|S463N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|463|rpoB_S463N|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGNSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1419|S463P|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|463|rpoB_S463P|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGPSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1420|S464P|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|464|rpoB_S464P|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSPQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1421|Q465K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|465|rpoB_Q465K|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSKLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1422|Q468I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|468|rpoB_Q468I|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSIFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1423|Q468L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|468|rpoB_Q468L|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSLFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1424|Q468R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|468|rpoB_Q468R|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSRFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1425|M470T|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|470|rpoB_M470T|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFTDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1426|D471G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|471|rpoB_D471G|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMGQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1427|D471Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|471|rpoB_D471Y|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMYQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1428|N474K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|474|rpoB_N474K|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQAKPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1429|N474KG|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|474|rpoB_N474KG|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQAKGPLAEL THKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQ IDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMG ANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNS GTCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEAR DTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVP HGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNP LGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLK LAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENI SRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1430|N474NH|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|474|rpoB_N474NH|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANHPLAEL THKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQ IDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMG ANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNS GTCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEAR DTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVP HGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNP LGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLK LAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENI SRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1431|A477D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|477|rpoB_A477D|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLDELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1432|A477G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|477|rpoB_A477G|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLGELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1433|A477V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|477|rpoB_A477V|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLVELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1434|H481D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|481|rpoB_H481D|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT DKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1435|H481Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|481|rpoB_H481Y|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT YKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1436|R484C|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|484|rpoB_R484C|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRCLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1437|R484H|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|484|rpoB_R484H|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRHLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1438|S486L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|486|rpoB_S486L|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLLALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1439|I527F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|527|rpoB_I527F|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLFNSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1440|I527L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|527|rpoB_I527L|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLLNSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1441|I527M|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|527|rpoB_I527M|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLMNSLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1442|S529L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|529|rpoB_S529L|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINLLSSYARVNEFGFIETPYRKVDLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1443|D550G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_000918664.1|550|rpoB_D550G|RIFAMYCIN|RIFAMPIN|Staphylococcus_aureus_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVGLDTHAITDQI DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG TCYNQRPIVAVGDVVEFNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD >1444|F3I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001010116.1|3|glpT_F3I|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_GlpT|wt_coherence=TRUE MNILKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1445|L27F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001010116.1|27|glpT_L27F|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_GlpT|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRFQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1446|W137R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001010116.1|137|glpT_W137R|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_GlpT|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGRPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1447|G352D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001010116.1|352|glpT_G352D|FOSFOMYCIN|FOSFOMYCIN|Staphylococcus_aureus_fosfomycin_resistant_GlpT|wt_coherence=TRUE MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF FMGTVSDRSNARIFLVLGLVLTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPDNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH >1448|R717L|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001132507.1|717|acrB_R717L|MACROLIDE|AZITHROMYCIN|Salmonella_azithromycin_resistant_AcrB|wt_coherence=TRUE MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA NMKDPISRTSGVGDVQLFGSQYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANALDTATAIRAELKKMEPFFPPG MKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL AIGLLVDDAIVVVENVERVMTEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL SVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRSTGRYLLLYLIIVVGMAYLFVRLP SSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLNKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE KNKVEAITQRATAAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVLPNG LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDINDWYVRGSDGQMVP FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL VEAMLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAIFFVPVFFVVVRRRFSRKSEDI EHSHSTEHR >1449|R717Q|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001132507.1|717|acrB_R717Q|MACROLIDE|AZITHROMYCIN|Salmonella_azithromycin_resistant_AcrB|wt_coherence=TRUE MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA NMKDPISRTSGVGDVQLFGSQYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANALDTATAIRAELKKMEPFFPPG MKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL AIGLLVDDAIVVVENVERVMTEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL SVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRSTGRYLLLYLIIVVGMAYLFVRLP SSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLNKEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE KNKVEAITQRATAAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVQPNG LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDINDWYVRGSDGQMVP FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAIS LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL VEAMLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAIFFVPVFFVVVRRRFSRKSEDI EHSHSTEHR >1450|L14F|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|14|pmrB_L14F|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRFMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1451|L14S|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|14|pmrB_L14S|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRSMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1452|L22P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|22|pmrB_L22P|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLIPLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1453|S29R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|29|pmrB_S29R|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLIRTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1454|T92A|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|92|pmrB_T92A|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRIARPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1455|P94Q|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|94|pmrB_P94Q|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRQLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1456|E121A|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|121|pmrB_E121A|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLAIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1457|S124P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|124|pmrB_S124P|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIEPVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1458|N130Y|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|130|pmrB_N130Y|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAIYQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1459|T147P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|147|pmrB_T147P|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFPADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1460|R155P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|155|pmrB_R155P|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELPTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1461|T156M|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|156|pmrB_T156M|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRMPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1462|T156P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|156|pmrB_T156P|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRPPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1463|V161G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|161|pmrB_V161G|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG GRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1464|V161L|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|161|pmrB_V161L|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG LRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1465|V161M|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|161|pmrB_V161M|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG MRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1466|E166K|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|166|pmrB_E166K|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLKLLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1467|M186I|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|186|pmrB_M186I|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQIMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1468|G206R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|206|pmrB_G206R|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSRNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1469|G206W|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|206|pmrB_G206W|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSWNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1470|S305R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001212189.1|305|pmrB_S305R|COLISTIN|COLISTIN|Salmonella_colistin_resistant_PmrB|wt_coherence=TRUE MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLT LLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPE SAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLREAFVRMDSRYGGIGL GLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA >1471|A51V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|51|gyrA_A51V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYVMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1472|N57K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|57|gyrA_N57K|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGKDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1473|A67S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|67|gyrA_A67S|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSSRVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1474|H80P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|80|gyrA_H80P|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPP GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1475|G81C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|81|gyrA_G81C|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH CDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1476|G81D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|81|gyrA_G81D|QUINOLONE|CIPROFLOXACIN|Escherichia_ciprofloxacin_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH DDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1477|D82G|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|82|gyrA_D82G|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GGSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1478|S83A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83A|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDAAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1479|S83F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83F|QUINOLONE/TRICLOSAN|QUINOLONE/TRICLOSAN|Escherichia_quinolone/triclosan_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDFAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1480|S83I|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83I|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDIAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1481|S83L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83L|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDLAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1482|S83V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDVAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1483|S83W|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|83|gyrA_S83W|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDWAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1484|A84P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|84|gyrA_A84P|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSPVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1485|A84V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|84|gyrA_A84V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSVVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1486|D87G|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|87|gyrA_D87G|QUINOLONE/TRICLOSAN|QUINOLONE/TRICLOSAN|Escherichia_quinolone/triclosan_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYGTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1487|D87H|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|87|gyrA_D87H|QUINOLONE/TRICLOSAN|QUINOLONE/TRICLOSAN|Escherichia_quinolone/triclosan_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYHTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1488|D87N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|87|gyrA_D87N|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1489|D87V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|87|gyrA_D87V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYVTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1490|D87Y|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|87|gyrA_D87Y|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYYTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1491|Q106H|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|106|gyrA_Q106H|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGHGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1492|Q106R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|106|gyrA_Q106R|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGRGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1493|A196E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281243.1|196|gyrA_A196E|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLEYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVESDDDVADDADE >1494|A67P|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|67|gyrA_A67P|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSPRVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1495|D72G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|72|gyrA_D72G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGGVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1496|V73I|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|73|gyrA_V73I|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDIIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1497|G81C|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|81|gyrA_G81C|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH CDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1498|G81D|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|81|gyrA_G81D|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH DDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1499|G81H|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|81|gyrA_G81H|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH HDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1500|G81S|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|81|gyrA_G81S|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH SDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1501|D82G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|82|gyrA_D82G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GGSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1502|D82N|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|82|gyrA_D82N|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GNSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1503|S83A|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|83|gyrA_S83A|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDAAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1504|S83Y|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|83|gyrA_S83Y|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDYAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1505|D87K|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|87|gyrA_D87K|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYKTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1506|L98V|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|98|gyrA_L98V|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSVRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1507|A119E|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|119|gyrA_A119E|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAEMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1508|A119S|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|119|gyrA_A119S|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAASMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1509|A119V|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|119|gyrA_A119V|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAVMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1510|A131G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|131|gyrA_A131G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIGHELMADLEKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1511|E139A|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281271.1|139|gyrA_E139A|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLAKETVDFVDNYDGTEKIPDVMP TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRA PTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE >1512|A56T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|56|parC_A56T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNTSAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1513|S57T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|57|parC_S57T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1514|F60I|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|60|parC_F60I|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKIKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1515|F60L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|60|parC_F60L|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKLKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1516|G78C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|78|parC_G78C|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHCDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1517|G78D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|78|parC_G78D|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHDDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1518|G78K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|78|parC_G78K|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHKDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1519|S80F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|80|parC_S80F|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDF ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1520|S80L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|80|parC_S80L|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDL ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1521|S80R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|80|parC_S80R|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDR ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1522|S80W|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|80|parC_S80W|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDW ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1523|S80Y|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|80|parC_S80Y|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDY ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1524|E84A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|84|parC_E84A|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYAAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1525|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|84|parC_E84K|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYKAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1526|E84R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|84|parC_E84R|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYRAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1527|E84V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|84|parC_E84V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYVAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1528|A108T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|108|parC_A108T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGTPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1529|A108V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001281881.1|108|parC_A108V|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGVPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE >1530|T66I|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|66|parC_T66I|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARIVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1531|G78D|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|78|parC_G78D|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHDDS ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1532|S80I|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|80|parC_S80I|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDI ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1533|S80R|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|80|parC_S80R|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDR ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1534|E84G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|84|parC_E84G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDS ACYGAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1535|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|84|parC_E84K|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDS ACYKAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1536|W106G|NA|NA|NA|NA|NA|NA|NA|NA|Salmonella|WP_001281910.1|106|parC_W106G|QUINOLONE|QUINOLONE|Salmonella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDS ACYEAMVLMAQPFSYRYPLVDGQGNGGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVR MRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADSDAYGDDRRSPL REREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPLVIEDEH DMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGE RGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE >1537|S80F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|80|parC_S80F|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDF SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1538|S80Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|80|parC_S80Y|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDY SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1539|Y83N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|83|parC_Y83N|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVNEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1540|E84G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|84|parC_E84G|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYGAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1541|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|84|parC_E84K|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYKAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1542|E84L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|84|parC_E84L|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYLAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1543|E84V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|84|parC_E84V|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYVAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1544|A116E|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|116|parC_A116E|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAEMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1545|A116V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001289586.1|116|parC_A116V|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParC|wt_coherence=TRUE MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDS SVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAVMRYTEAKLSLLAEELLRDINKETVSFISNYDDTTLEPMVLPSRF PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVR SKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNS DLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKR DAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERL SLIEAEIEEIKIDKEVMVPSEEVILSMTRHGYIKRTSIRSYNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLF IPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKTTRFNKPLIATKVKEND DLISVMRFEKDQLITIITNKGMSLTYNTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKI LQVAKRAQRGITLLKELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMYIS >1546|P403L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001295325.1|403|lon_P403L|TETRACYCLINE|TIGECYCLINE|Escherichia_tigecycline_resistant_Lon|wt_coherence=TRUE MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQM LKLPDGTVKVLVEGLQRARISALSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE LGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEIL DTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIG SMLGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAP LLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLL LDKSLKHIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQA ALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLK EKLLAAHRGGIKTVLIPFENKRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK >1547|L10P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|10|pmrB_L10P|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISPRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1548|L10R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|10|pmrB_L10R|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISRRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1549|L14R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|14|pmrB_L14R|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRRILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1550|C84R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|84|pmrB_C84R|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFIRYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1551|C84Y|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|84|pmrB_C84Y|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFIYYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1552|P94L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|94|pmrB_P94L|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRLLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1553|P94Q|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|94|pmrB_P94Q|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRQLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1554|P94S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|94|pmrB_P94S|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRSLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1555|E121K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|121|pmrB_E121K|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLKIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1556|E121Q|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|121|pmrB_E121Q|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLQIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1557|T147A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|147|pmrB_T147A|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFAADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1558|T156M|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|156|pmrB_T156M|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRMPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1559|A159P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|159|pmrB_A159P|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLPG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1560|A159V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|159|pmrB_A159V|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLVG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1561|V161G|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|161|pmrB_V161G|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG GRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1562|E166K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|166|pmrB_E166K|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLKLLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1563|G206D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001300761.1|206|pmrB_G206D|COLISTIN|COLISTIN|Escherichia_colistin_resistant_PmrB|wt_coherence=TRUE MHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSDNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL GLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQYVANQI >1564|Y151V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_001718014.1|151|fabG_Y151V|TRICLOSAN|TRICLOSAN|Escherichia_triclosan_resistant_FabG|wt_coherence=TRUE MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEV DILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANVAAAKAGLVG FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGG MYMV >1565|S79F|NA|NA|NA|NA|NA|NA|NA|NA|Streptococcus_pneumoniae|WP_001836116.1|79|parC_S79F|QUINOLONE|QUINOLONE|Streptococcus_pneumoniae_quinolone_resistant_ParC|wt_coherence=TRUE MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDFS IYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRS KTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTD LQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASENKAD AKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATPRLS SLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYR PIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAKLKD DTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIE EILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNGSF ISDTISDEEVFDAYLQEVVTEDK >1566|S79Y|NA|NA|NA|NA|NA|NA|NA|NA|Streptococcus_pneumoniae|WP_001836116.1|79|parC_S79Y|QUINOLONE|QUINOLONE|Streptococcus_pneumoniae_quinolone_resistant_ParC|wt_coherence=TRUE MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDYS IYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRS KTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTD LQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASENKAD AKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATPRLS SLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYR PIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAKLKD DTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIE EILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNGSF ISDTISDEEVFDAYLQEVVTEDK >1567|D83H|NA|NA|NA|NA|NA|NA|NA|NA|Streptococcus_pneumoniae|WP_001836116.1|83|parC_D83H|QUINOLONE|QUINOLONE|Streptococcus_pneumoniae_quinolone_resistant_ParC|wt_coherence=TRUE MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSS IYHAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRS KTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTD LQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALIRASENKAD AKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKNFATPRLS SLEDTAKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYR PIHELADIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTPWRTYRSKSVKYAKLKD DTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIE EILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNGSF ISDTISDEEVFDAYLQEVVTEDK >1568|G78S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|78|parE_G78S|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRSMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1569|R136G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|136|parE_R136G|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHGDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1570|D432H|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|432|parE_D432H|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGHSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1571|D432N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|432|parE_D432N|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGNSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1572|D432V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|432|parE_D432V|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGVSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1573|D443E|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|443|parE_D443E|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRERKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1574|R444S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|444|parE_R444S|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDSKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1575|P451S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|451|parE_P451S|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILSLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1576|N470S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|470|parE_N470S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKSEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1577|P585S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_001837315.1|585|parE_P585S|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_ParE|wt_coherence=TRUE MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMP TGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLH DVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREG LTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGK KNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTI GAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEE LNKLQKELGKGFTLQRYKGLGEMNSEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQE DQSILDNSEVQVLENDQFDEEEI >1578|S80I|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002371880.1|82|parC_S80I|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_ParC|wt_coherence=FALSE MEKRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFSMNKDGNTFDKGFRKSAKSVGNIMGNYHPIG DSSIYEAMVRLSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSQLSGELLKDIDKNTVDFVWNFDDTEKEPTVLPA KYPNLLVNGSTGISAGYATEIPTHNLAEIIDGTVYLIDHPNASLEKLMEYIPGPDFPTGGILQGKAEIKKAYETGRGKVI LRAKTKIEPLKGGKQQIVISEIPYEVNKATLVKKMDEIRLNKKVDGIAEVRDESDRTGLQIVVELKKDVNAEGILNYLFK NTELQINYNFNMVAIDNMTPQQVGLKRILESYITHRKSVIINRCQFELDKARKREHIVAGLIKALSILDKVIATIRGSKD KKDAKKNLVSDYAFTEEQAEAIVTLQLYRLTNTDITDLQEEAKTLEQQIAELLNILNNENELFSVMKKELREVKKQYGNP RLTQIEEEIQEIKIETAVLVAQEDVVVTVTHEGYIKRSSIRSYTASKPEEIGMKEGDFLLYAGEVNTLDHLLLVTNKGNM IYRPVHELPDLRWKEIGEHISQTILNLAIDESIIAVYPYKELSPTKTFVFITKAGMIKQTKMADFEPWRTYKSRPTSCMK LKSDQDEITNVYLTNDQDLLDVFLVSNRGFGLRYPLYEVPVVGSKAAGVKSMNLKEDDYVVNGLLVHSEGDTPIVIVTQR GGVKRMLAQELTQLGRAKRGLMVLRELKKNPHRVVFMSESTDLDLLVTTQKGTQEVIQSKNYPISERTSNGSFVIDEQKD GQVMEVHEMHSAVIEEEQTN >1579|S80R|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002371880.1|82|parC_S80R|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_ParC|wt_coherence=FALSE MEKRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFSMNKDGNTFDKGFRKSAKSVGNIMGNYHPRG DSSIYEAMVRLSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSQLSGELLKDIDKNTVDFVWNFDDTEKEPTVLPA KYPNLLVNGSTGISAGYATEIPTHNLAEIIDGTVYLIDHPNASLEKLMEYIPGPDFPTGGILQGKAEIKKAYETGRGKVI LRAKTKIEPLKGGKQQIVISEIPYEVNKATLVKKMDEIRLNKKVDGIAEVRDESDRTGLQIVVELKKDVNAEGILNYLFK NTELQINYNFNMVAIDNMTPQQVGLKRILESYITHRKSVIINRCQFELDKARKREHIVAGLIKALSILDKVIATIRGSKD KKDAKKNLVSDYAFTEEQAEAIVTLQLYRLTNTDITDLQEEAKTLEQQIAELLNILNNENELFSVMKKELREVKKQYGNP RLTQIEEEIQEIKIETAVLVAQEDVVVTVTHEGYIKRSSIRSYTASKPEEIGMKEGDFLLYAGEVNTLDHLLLVTNKGNM IYRPVHELPDLRWKEIGEHISQTILNLAIDESIIAVYPYKELSPTKTFVFITKAGMIKQTKMADFEPWRTYKSRPTSCMK LKSDQDEITNVYLTNDQDLLDVFLVSNRGFGLRYPLYEVPVVGSKAAGVKSMNLKEDDYVVNGLLVHSEGDTPIVIVTQR GGVKRMLAQELTQLGRAKRGLMVLRELKKNPHRVVFMSESTDLDLLVTTQKGTQEVIQSKNYPISERTSNGSFVIDEQKD GQVMEVHEMHSAVIEEEQTN >1580|E84A|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002371880.1|86|parC_E84A|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_ParC|wt_coherence=FALSE MEKRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFSMNKDGNTFDKGFRKSAKSVGNIMGNYHPHG DSAIYEAMVRLSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSQLSGELLKDIDKNTVDFVWNFDDTEKEPTVLPA KYPNLLVNGSTGISAGYATEIPTHNLAEIIDGTVYLIDHPNASLEKLMEYIPGPDFPTGGILQGKAEIKKAYETGRGKVI LRAKTKIEPLKGGKQQIVISEIPYEVNKATLVKKMDEIRLNKKVDGIAEVRDESDRTGLQIVVELKKDVNAEGILNYLFK NTELQINYNFNMVAIDNMTPQQVGLKRILESYITHRKSVIINRCQFELDKARKREHIVAGLIKALSILDKVIATIRGSKD KKDAKKNLVSDYAFTEEQAEAIVTLQLYRLTNTDITDLQEEAKTLEQQIAELLNILNNENELFSVMKKELREVKKQYGNP RLTQIEEEIQEIKIETAVLVAQEDVVVTVTHEGYIKRSSIRSYTASKPEEIGMKEGDFLLYAGEVNTLDHLLLVTNKGNM IYRPVHELPDLRWKEIGEHISQTILNLAIDESIIAVYPYKELSPTKTFVFITKAGMIKQTKMADFEPWRTYKSRPTSCMK LKSDQDEITNVYLTNDQDLLDVFLVSNRGFGLRYPLYEVPVVGSKAAGVKSMNLKEDDYVVNGLLVHSEGDTPIVIVTQR GGVKRMLAQELTQLGRAKRGLMVLRELKKNPHRVVFMSESTDLDLLVTTQKGTQEVIQSKNYPISERTSNGSFVIDEQKD GQVMEVHEMHSAVIEEEQTN >1581|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002371880.1|86|parC_E84K|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_ParC|wt_coherence=FALSE MEKRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFSMNKDGNTFDKGFRKSAKSVGNIMGNYHPHG DSKIYEAMVRLSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSQLSGELLKDIDKNTVDFVWNFDDTEKEPTVLPA KYPNLLVNGSTGISAGYATEIPTHNLAEIIDGTVYLIDHPNASLEKLMEYIPGPDFPTGGILQGKAEIKKAYETGRGKVI LRAKTKIEPLKGGKQQIVISEIPYEVNKATLVKKMDEIRLNKKVDGIAEVRDESDRTGLQIVVELKKDVNAEGILNYLFK NTELQINYNFNMVAIDNMTPQQVGLKRILESYITHRKSVIINRCQFELDKARKREHIVAGLIKALSILDKVIATIRGSKD KKDAKKNLVSDYAFTEEQAEAIVTLQLYRLTNTDITDLQEEAKTLEQQIAELLNILNNENELFSVMKKELREVKKQYGNP RLTQIEEEIQEIKIETAVLVAQEDVVVTVTHEGYIKRSSIRSYTASKPEEIGMKEGDFLLYAGEVNTLDHLLLVTNKGNM IYRPVHELPDLRWKEIGEHISQTILNLAIDESIIAVYPYKELSPTKTFVFITKAGMIKQTKMADFEPWRTYKSRPTSCMK LKSDQDEITNVYLTNDQDLLDVFLVSNRGFGLRYPLYEVPVVGSKAAGVKSMNLKEDDYVVNGLLVHSEGDTPIVIVTQR GGVKRMLAQELTQLGRAKRGLMVLRELKKNPHRVVFMSESTDLDLLVTTQKGTQEVIQSKNYPISERTSNGSFVIDEQKD GQVMEVHEMHSAVIEEEQTN >1582|R177RI|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002381168.1|177|liaF_R177RI|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_LiaF|wt_coherence=TRUE MNNPWRFFIVAEALLFILALWQIVHNPGLAVLLTIGVLLVAYVSRKASKTHFNNFQFVLGVVFIVIGAMNSTAVWFMLIF GVLFIGLKGFEISGVDIAERAPWRKKQMIMVETAAKEPKNGKRFKRRWFANERIGNNIYEWDDINIDLISGDTIIDLGNT LLPKEDNIIIIRKGFGRITRILVPLGVAILLEHSTFYGTVRFEEEKYQLKNESLKIYSNDYDTNLRRLKIMTNTLVGDVE VIRV >1583|R177del|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002381168.1|177|liaF_R177del|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_LiaF|wt_coherence=TRUE MNNPWRFFIVAEALLFILALWQIVHNPGLAVLLTIGVLLVAYVSRKASKTHFNNFQFVLGVVFIVIGAMNSTAVWFMLIF GVLFIGLKGFEISGVDIAERAPWRKKQMIMVETAAKEPKNGKRFKRRWFANERIGNNIYEWDDINIDLISGDTIIDLGNT LLPKEDNIIIIRKGFGTRILVPLGVAILLEHSTFYGTVRFEEEKYQLKNESLKIYSNDYDTNLRRLKIMTNTLVGDVEVI RV >1584|NFQ77del|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_002413481.1|77|cls_NFQ77del|LIPOPEPTIDE|DAPTOMYCIN|Enterococcus_faecalis_daptomycin_resistant_Cls|wt_coherence=TRUE MILSVLTVIYFINAIIAGITILLKPRDVAAIWAWLLVLIALPVFGFFLYLFFGRGLTDKKKFYLQQSDLRELENFQEESF ELYSQKMPTEEQQQFTDFFSSLNRMPLTKKNDVEIFTDGTEKFNALMADIKKAQHSIHIEYYAFVTDHIGTKILNLLEEK AAEGVEVRLLYDAFGSKGTKVHHLNELKKNGGFVQTFITSQKALLKFRLNYHDHRKIVVIDGKVGYIGGFNVADQYAGTT KKFGYWRDTHLRIQGPATSLLQMRFLMDWNVSSPEKNRVAYQLDYFFKLEALVPEANTSIQMIASGPNSDREQIKLAFIK LITSAKKRVWIQTPYLVPDDSVLAALKVAAASGVDVKIMIPDKPDHPFIYRATQYYGRLLMKENIEILIYNGGFLHAKTM IMDDEVCTVGSANQDIRSYKLNFEANAVLYDKKIIDQLEAIFLEDRKKCTTMTPEVVRDMSKWLIFKQQISRLFSPIL >1585|T86A|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|86|gyrA_T86A|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDAAVYDALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1586|T86I|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|86|gyrA_T86I|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDIAVYDALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1587|T86K|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|86|gyrA_T86K|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDKAVYDALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1588|T86V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|86|gyrA_T86V|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDVAVYDALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1589|D90N|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|90|gyrA_D90N|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDTAVYNALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1590|D90Y|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|90|gyrA_D90Y|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDTAVYYALVRMAQDFSMRYPSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1591|P104S|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779062.1|104|gyrA_P104S|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFNKDSDIELIDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSAYKKSARIVGDVIGKY HPHGDTAVYDALVRMAQDFSMRYSSIDGQGNFGSIDGDGAAAMRYTEARMTILAEELLRDIDKDTVDFVPNYDDSMSEPD VLPARVPNLLLNGSSGIAVGMATNIPPHSLNELVDGLLYLLDHKDASLEDLMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKIRAKTHIEKKSNKDIIVIDELPYQTNKARLIEQIAELVKEKQIEGISEVRDESDREGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLIELLNLFLNHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SPDNTTARDSLVAKFGLTELQANAILDMKLGRLTGLEREKIENELAELMKEIARLDEILKSETLLENLIRDELKEIKSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADEKIMAIIPTTDFDENKSLCFFTKNGIVKRTNLSEYQNIRSVGVKA INLDENDELVTAIIVQRDENEETGLLDDDSLNDENTNSDENLIESIKGKMLFAVTKKGMCIKFPLAKVREIGRVSRGVTA IKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTDKTKELISVVIVDESMDLMALTSS GKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEELEDEISDENLDLNL >1592|A84D|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779996.1|84|50S_L22_A84D|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAGAVLKRF RPRDRGSASRIRKPTSHILVEVAKAEVKTEAKKAVAKKTPVKKTSTKKVTAEKES >1593|G86E|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779996.1|86|50S_L22_G86E|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAGAVLKRF RPRARESASRIRKPTSHILVEVAKAEVKTEAKKAVAKKTPVKKTSTKKVTAEKES >1594|G86V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779996.1|86|50S_L22_G86V|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAGAVLKRF RPRARVSASRIRKPTSHILVEVAKAEVKTEAKKAVAKKTPVKKTSTKKVTAEKES >1595|A88E|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779996.1|88|50S_L22_A88E|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAGAVLKRF RPRARGSESRIRKPTSHILVEVAKAEVKTEAKKAVAKKTPVKKTSTKKVTAEKES >1596|A103V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002779996.1|103|50S_L22_A103V|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVVVKSCRVDAGAVLKRF RPRARGSASRIRKPTSHILVEVVKAEVKTEAKKAVAKKTPVKKTSTKKVTAEKES >1597|G86A|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002843095.1|86|cmeR_G86A|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_CmeR|wt_coherence=TRUE MNSNRTPSQKVLARQEKIKAVALELFLTKGYQETSLSDIIKLSGGSYSNIYDGFKSKEGLFFEILDDICKKHFHLIYSKT QEIENATLKEILTSFGLAFIEIFNQPEAVAFGKIIYSQVYDKDRHLANWIENNQQNFSYNILMGFFKQQNNSYMKKNAEK LAVLFCTMLKEPYHHLNVLINAPLKNKKEQKEHVEFVVNVFLNGINSSKA >1598|A84D|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|84|50S_L22_A84D|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRDRGSASRIRKPTSHILVEVAKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1599|G86E|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|86|50S_L22_G86E|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRARESASRIRKPTSHILVEVAKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1600|G86V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|86|50S_L22_G86V|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRARVSASRIRKPTSHILVEVAKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1601|A88E|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|88|50S_L22_A88E|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRARGSESRIRKPTSHILVEVAKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1602|A103C|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|103|50S_L22_A103C|MACROLIDE|ERYTHROMYCIN|Campylobacter_erythromycin_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRARGSASRIRKPTSHILVEVCKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1603|A103V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002851214.1|103|50S_L22_A103V|MACROLIDE|MACROLIDE|Campylobacter_macrolide_resistant_50S_L22|wt_coherence=TRUE MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRF RPRARGSASRIRKPTSHILVEVVKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES >1604|A70T|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|70|gyrA_A70T|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSTRIVGAVIGRY HPHGDTAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1605|D85Y|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|85|gyrA_D85Y|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGYTAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1606|T86A|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|86|gyrA_T86A|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDAAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1607|T86K|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|86|gyrA_T86K|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDKAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1608|T86V|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|86|gyrA_T86V|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDVAVYDALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1609|D90A|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|90|gyrA_D90A|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDTAVYAALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1610|D90N|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|90|gyrA_D90N|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDTAVYNALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1611|D90T|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|90|gyrA_D90T|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDTAVYTALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1612|D90Y|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|90|gyrA_D90Y|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDTAVYYALVRMAQDFSMRYPSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1613|P104S|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_002857904.1|104|gyrA_P104S|QUINOLONE|QUINOLONE|Campylobacter_quinolone_resistant_GyrA|wt_coherence=TRUE MENIFSKDSDIELVDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRY HPHGDTAVYDALVRMAQDFSMRYSSITGQGNFGSIDGDSAAAMRYTEAKMSKLSHELLKDIDKDTVDFVPNYDGSESEPD VLPSRVPNLLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDASLEEIMQFIKGPDFPTGGIIYGKKGIIEAYRTGR GRVKVRAKTHIEKKTNKDVIVIDELPYQTNKARLIEQIAELVKERQIEGISEVRDESNKEGIRVVIELKREAMSEIVLNN LFKSTTMESTFGVIMLAIHNKEPKIFSLLELLNLFLTHRKTVIIRRTIFELQKARARAHILEGLKIALDNIDEVIALIKN SSDNNTARDSLVAKFGLSELQANAILDMKLGRLTGLEREKIENELAELMKEIARLEEILKSETLLENLIRDELKEIRSKF DVPRITQIEDDYDDIDIEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGKLAVTTYDDDFIESFFTANTHDTLMFV TDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQAEEKIMAIIPTTDFDESKSLCFFTKNGIVKRTNLSEYQNIRSVGVRA INLDENDELVTAIIVQRDEDEIFATGGEENLENQEIENLDDENLENEESVSTQGKMLFAVTKKGMCIKFPLAKVREIGRV SRGVTAIKFKEKNDELVGAVVIENDEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTEKTKDLISVVIVDETMDL MALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVENDEVVSIAKCPKEENDEDELSDENFGLDLQ >1614|S42N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002895659.1|42|pmrA_S42N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrA|wt_coherence=TRUE MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLANNHYSLIVLDLGLPDEDGLHFLSRMRREKMTQPVLILTA RDTLEDRISGLDTGADDYLVKPFALEELNARIRALLRRHNNQGDNEISVGNLRLNVTRRLVWLGETALDLTPKEYALLSR LMMKAGSPVHREILYNDIYSWDNEPATNTLEVHIHNLREKIGKSRIRTVRGFGYMLANNIDTE >1615|G53C|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002895659.1|53|pmrA_G53C|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrA|wt_coherence=TRUE MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLIVLDLCLPDEDGLHFLSRMRREKMTQPVLILTA RDTLEDRISGLDTGADDYLVKPFALEELNARIRALLRRHNNQGDNEISVGNLRLNVTRRLVWLGETALDLTPKEYALLSR LMMKAGSPVHREILYNDIYSWDNEPATNTLEVHIHNLREKIGKSRIRTVRGFGYMLANNIDTE >1616|G53S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002895659.1|53|pmrA_G53S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrA|wt_coherence=TRUE MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLIVLDLSLPDEDGLHFLSRMRREKMTQPVLILTA RDTLEDRISGLDTGADDYLVKPFALEELNARIRALLRRHNNQGDNEISVGNLRLNVTRRLVWLGETALDLTPKEYALLSR LMMKAGSPVHREILYNDIYSWDNEPATNTLEVHIHNLREKIGKSRIRTVRGFGYMLANNIDTE >1617|A14S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|14|mgrB_A14S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIISGCLLLWTQMLNVMCDQDVQFFSGICTINKFIPW >1618|W20R|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|20|mgrB_W20R|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLRTQMLNVMCDQDVQFFSGICTINKFIPW >1619|L24H|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|24|mgrB_L24H|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMHNVMCDQDVQFFSGICTINKFIPW >1620|M27K|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|27|mgrB_M27K|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVKCDQDVQFFSGICTINKFIPW >1621|C28F|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|28|mgrB_C28F|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMFDQDVQFFSGICTINKFIPW >1622|C28Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|28|mgrB_C28Y|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMYDQDVQFFSGICTINKFIPW >1623|D31N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|31|mgrB_D31N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQNVQFFSGICTINKFIPW >1624|F35I|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|35|mgrB_F35I|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFISGICTINKFIPW >1625|G37S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|37|mgrB_G37S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFFSSICTINKFIPW >1626|C39Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|39|mgrB_C39Y|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFFSGIYTINKFIPW >1627|I45T|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|45|mgrB_I45T|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFFSGICTINKFTPW >1628|W47R|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_002911375.1|47|mgrB_W47R|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_MgrB|wt_coherence=TRUE MKKLRWVLLIVIIAGCLLLWTQMLNVMCDQDVQFFSGICTINKFIPR >1629|R16C|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|16|phoQ_R16C|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVCFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1630|A20P|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|20|phoQ_A20P|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLPTAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1631|L26P|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|26|phoQ_L26P|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVPVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1632|L96P|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|96|phoQ_L96P|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLPWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1633|S174N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|174|phoQ_S174N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLNIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1634|L348Q|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|348|phoQ_L348Q|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSQTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1635|G385S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|385|phoQ_G385S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMSNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1636|L396Q|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|396|phoQ_L396Q|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCQEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRADTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1637|D438N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004147969.1|438|phoQ_D438N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoQ|wt_coherence=TRUE MKGLLRHIFPLSLRVRFLLATAGVVLVLSLAYGMVALVGYSVSFDKTTFRLLRGESNLFYMLARWENGAIDVDIPENLNM ESPTVTLIYDEQGKLLWAQRDVPWLAKRIQPEWLKRNGFHEIEADVDSSSMLLRNNHEIQEQLDAIREQGDDSEMTHSVA INLYPATSKMPQLSIVVVDTIPVELKRSYMVWSWFVYVLAANLLLVIPLLWVAAWWSLRPIESLAKEVRELEEHHREKLN PNTTRELTRLVSNLNRLVRSERERYDKYRTTLTDLTHSLKTPLAVMQSTLRSLRGEKISVDEAEPVMLEQISRISQQIGY YLHRASMRSGGTLLSRELHPIAPLLDSLTSALNKVYQRKGVNISLDISPEITFVGEQNDFMEVMGNVLDNACKYCLEFVE VSVRQTTDSHLHILVEDDGPGIPQSQRRAVFDRGQRANTLRPGQGVGLSVAREIVEQYDGEIIAGESLLGGACMEVVFGR QQMEDKQS >1638|V3F|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004150807.1|3|phoP_V3F|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoP|wt_coherence=TRUE MRFLVVEDNALLRHHLKVQLQELGHQVDAAEDAREADYYLGEHLPDIAIVDLGLPDEDGLSLIRRWRSHDVSLPVLVLTA REGWQDKVEVLSAGADDYVTKPFHIEEVAARMQALLRRNSGLASQVISLPPFQVDLSRRELSVNDQPIKLTAFEYTIMET LIRNRGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAEYPQDVITTVRGQGYLFELR >1639|I201N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004150807.1|201|phoP_I201N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PhoP|wt_coherence=TRUE MRVLVVEDNALLRHHLKVQLQELGHQVDAAEDAREADYYLGEHLPDIAIVDLGLPDEDGLSLIRRWRSHDVSLPVLVLTA REGWQDKVEVLSAGADDYVTKPFHIEEVAARMQALLRRNSGLASQVISLPPFQVDLSRRELSVNDQPIKLTAFEYTIMET LIRNRGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKNQAEYPQDVITTVRGQGYLFELR >1640|R14del|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|14|pmrB_R14del|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGLA LYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLAG LRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLTD IENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIGL GLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1641|L17Q|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|17|pmrB_L17Q|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLQTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1642|L82R|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|82|pmrB_L82R|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ARYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1643|S85R|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|85|pmrB_S85R|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYIRMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1644|T140P|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|140|pmrB_T140P|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLPLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1645|T157P|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|157|pmrB_T157P|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRPPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1646|S208N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|208|pmrB_S208N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGNYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1647|Y209del|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|209|pmrB_Y209del|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSQQVLLLDDVVKPLQDELEAMLAQRQQRLLLTD IENETVVSGDATLIRVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIGL GLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1648|R256G|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004179093.1|256|pmrB_R256G|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_PmrB|wt_coherence=TRUE MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGL ALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLA GLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLT DIENETVVSGDATLIGVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIG LGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH >1649|Q10L|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|10|crrB_Q10L|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRLILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1650|Y31H|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|31|crrB_Y31H|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSHLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1651|F84S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|84|crrB_F84S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARISNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1652|L94M|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|94|crrB_L94M|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSMKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1653|W140R|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|140|crrB_W140R|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLRNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1654|N141I|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|141|crrB_N141I|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWIAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1655|N141Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|141|crrB_N141Y|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWYAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1656|P151L|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|151|crrB_P151L|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTLVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1657|P151S|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|151|crrB_P151S|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTSVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1658|G183V|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|183|crrB_G183V|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEVLTNLIEDLRVVSSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1659|S195N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_004184324.1|195|crrB_S195N|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_CrrB|wt_coherence=TRUE MNKETILSRQILTYMLLLTFVIIAIAILGSYLFYSFLIYYLPGGMNEGSEDAMTFLDWMWILMASITSLVVALFFTVKLS ARIFNPLNDVAYSLKQISQGNLSARAFNSSSKLGEMNRLVNDFNEMAEKLQTLDAQRNLWNAAIAHELRTPVTILRGRLQ GLVDGVFEPEPSLFRNLLKQTEGLTNLIEDLRVVNSSGGAGYSLMLSEVDLKATISNALDTFWPDFDKKHFKIVTEINQQ YCVCDPLRIIQCLTVLFDNALKYSTSQTLLIKNGITGNDNFIIVQDQGPGIPEELQKSLFQPFQRGEYAKNINPEGCGLG LSVVKAIMCAHGGDVSYSLTPENGSLFKLSWPV >1660|S127L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_010956585.1|127|gyrB_S127L|AMINOCOUMARIN|AMINOCOUMARIN|Staphylococcus_aureus_aminocoumarin_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGLSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1661|D436N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_010956585.1|436|gyrB_D436N|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGNSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1662|E476D|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_010956585.1|476|gyrB_E476D|QUINOLONE|QUINOLONE|Staphylococcus_aureus_quinolone_resistant_GyrB|wt_coherence=TRUE MTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTD NGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFD LKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLN ENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEDKDRL SGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKARE VTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNDIRQM ITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRE LDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYAN LDF >1663|A473AA|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_014614750.1|473|rpoB_A473AA|RIFAMYCIN|RIFAMPIN|Staphylococcus_pseudintermedius_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQFVQYGRHRKRRNYARISEVLELPNLIEIQTKSYDWFLKEGLLEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKDQEVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYFNEKLDKNGRVNYDA TVIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGYSTDQEIIELIGDNEYLRNTLEKDSTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKANKKLHLKHRLFNQKLAEPIVNTETGEIVAEEGTVLDRRKLDEIMD VLETNANAQVYELPNSIIDEPVEIQSIKVYVPNDDEERTTTVIGNAFPDSEVKCITPADIVASMSYFFNLLHGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTDSITPQQLINIRPVIASIKEFFGSSQLSQFMDQAANPLAEL THKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDIETNTITDQ IDYLTADEEDSYVVAQANSRLDENGRFIDDEIVCRFRGNNTTMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMG ANMQRQAVPLLNPESPFVGTGMEHVAARDSGAAVISKYRGRVEHVQSSEILVRRLVEENGQEVDGTLDRYPLAKFKRSNS GTCYNQRPIIAKGDIVEKGEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEAR DTKLGPEEITRDIPNVSENALKNLDDRGIVYVGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVP HGAGGIVLDVKVFNREEGDDSLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNP LGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLK LAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENI SRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMRDLDDDDIPDRKVNMQPSSVPESQKEFNEQ >1664|H481Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_014614750.1|481|rpoB_H481Y|RIFAMYCIN|RIFAMPIN|Staphylococcus_pseudintermedius_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQFVQYGRHRKRRNYARISEVLELPNLIEIQTKSYDWFLKEGLLEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKDQEVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYFNEKLDKNGRVNYDA TVIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGYSTDQEIIELIGDNEYLRNTLEKDSTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKANKKLHLKHRLFNQKLAEPIVNTETGEIVAEEGTVLDRRKLDEIMD VLETNANAQVYELPNSIIDEPVEIQSIKVYVPNDDEERTTTVIGNAFPDSEVKCITPADIVASMSYFFNLLHGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTDSITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT YKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDIETNTITDQI DYLTADEEDSYVVAQANSRLDENGRFIDDEIVCRFRGNNTTMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLLNPESPFVGTGMEHVAARDSGAAVISKYRGRVEHVQSSEILVRRLVEENGQEVDGTLDRYPLAKFKRSNSG TCYNQRPIIAKGDIVEKGEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSENALKNLDDRGIVYVGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDSLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMRDLDDDDIPDRKVNMQPSSVPESQKEFNEQ >1665|S486L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_014614750.1|486|rpoB_S486L|RIFAMYCIN|RIFAMPIN|Staphylococcus_pseudintermedius_rifampin_resistant_RpoB|wt_coherence=TRUE MAGQFVQYGRHRKRRNYARISEVLELPNLIEIQTKSYDWFLKEGLLEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE SKNRDATYAAPLRVKVRLIIKETGEVKDQEVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYFNEKLDKNGRVNYDA TVIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGYSTDQEIIELIGDNEYLRNTLEKDSTENTEQALLEIYERL RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKANKKLHLKHRLFNQKLAEPIVNTETGEIVAEEGTVLDRRKLDEIMD VLETNANAQVYELPNSIIDEPVEIQSIKVYVPNDDEERTTTVIGNAFPDSEVKCITPADIVASMSYFFNLLHGIGYTDDI DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTDSITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT HKRRLLALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDIETNTITDQI DYLTADEEDSYVVAQANSRLDENGRFIDDEIVCRFRGNNTTMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA NMQRQAVPLLNPESPFVGTGMEHVAARDSGAAVISKYRGRVEHVQSSEILVRRLVEENGQEVDGTLDRYPLAKFKRSNSG TCYNQRPIIAKGDIVEKGEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD TKLGPEEITRDIPNVSENALKNLDDRGIVYVGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH GAGGIVLDVKVFNREEGDDSLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMRDLDDDDIPDRKVNMQPSSVPESQKEFNEQ >1666|C161Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_014906821.1|161|arnC_C161Y|COLISTIN|COLISTIN|Klebsiella_colistin_resistant_ArnC|wt_coherence=TRUE MLTYPPVKKVSVVIPVYNEQDSLPELLRRSDAACATLGRQYEILLIDDGSSDDSARMLTEAAEAEGSHVVAVLLNRNYGQ HSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSIFRKTASKMINRLIQRTTGKAMGDYG YMLRAYRRHIIDAMLNCHERSTFIPILANTFARRAVEIPVMHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSIFG SVIALLGFAFGLLLVVLRLAFGPQWAAEGVFMLFAVLFMFIGAQFVGMGLLGEYIGRIYNDVRARPRYFIQRVVRQPETA SKEEDRS >1667|Q557E|NA|NA|NA|NA|NA|NA|NA|NA|Streptococcus_agalactiae|WP_017647104.1|557|pbp2x_Q557E|BETA-LACTAM|BETA-LACTAM|Streptococcus_agalactiae_beta-lactam_resistant_Pbp2x|wt_coherence=TRUE MTFFKKLKKIFLDYVIHIRDRRSPQKNRERVGQNLMILTIFLFFIFIINFVIIVGTDSKFGVNLSKEAKKVYQQSMTVQA KRGTIYDRNGNPIAEDATTYSLYAIISKNYTTATGQKLYVQPSQYEKVASILENKLGMKKNLVLKQLNQKKLFQVSFGSS GSGLSYTKMADIKKTMEKSDIKGIGFSTSPGRIYPNGIFASQFIGFTLPQDDGDGKKLVGNTGLEAALNKVLSGTDGKVT YEKDRSGNVLLGTATTERRAVNGKDIYTTLSEPIQTVLETQMDVFAEKTKGKFASATVVNAKTGEILATSQRPTYNPSTL KGYDKKNLGTYNTLLYDNFFEPGSTMKVMTLASAIDSKHFNSTEVYNSAQYKIADAVIRDWDVNEGLSSGSYMTFPQGFA HSSNVGMVTLEQKMGRDKWLNYLSKFKFGYPTRFGMLHESGGLFPSDNEVTIAMSSFGQGIGVTQVQMLRAFTSISNDGV MLQPQFISSIYDPNTGTSRTARKEVVGKPVSKEAASKTRDYMVTVGTDPYYGTLYAAGAPVIQVGNQSVAVKSGTAEIAQ EGGGGYLQGKNDTINSVVAMVPSENPDFIMYVTIQQPEKFSITFWKDVVNPVLEQATAMKETILKPGLNDSEHQTKYKLS KIVGENPGHVAEELRRNLVQPIILGNGSKVSKVSKRPGANLAENEQLLVLTNKLTELPDMYGWSKANVEQFAKWTGIKVS YKGSTSGKVRKQSIDVGKSINKIKKIKITIGD >1668|S80I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|80|grlA_S80I|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDI SVYDAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1669|S80R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|80|grlA_S80R|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDR SVYDAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1670|D84G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|84|grlA_D84G|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDS SVYGAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1671|D84H|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|84|grlA_D84H|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDS SVYHAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1672|D84N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|84|grlA_D84N|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDS SVYNAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1673|D84Y|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_019167736.1|84|grlA_D84Y|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GrlA|wt_coherence=TRUE MAEIIQNLPLVDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYSMYSNGNTYDKHFRKSAKTVGDVIGQLHPHGDS SVYYAMVRLSQDWKLRHVLVEMHGNNGSIDNDPPAAMRYTEAKLSQLSEQLLRDIHKDTVDFVPNYDDTEMEPMVLPARF PNLLVNGSTGISAGYATDIPPHNLAEVITATLKYIDNPDLTVKQLMQYIKGPDFPTGGIVQGIDGIRKAYETGKGKVIVR AKADIETLRNGRSQIIVTEIPYEVNKSSLVKKIDELRADKKVEGIVEVRDETDRSGLRVAVELKKDVNATSILNFLYKNT DLQVAYNFNMVAITEGRPKLMGIKPIISSYLNHQIEVVTRRTSFDLKHTEERMHIVEGLMKALSILDEVIVLIRNSKNKR DAKNNLVATYDFTETQAEAIVMLQLYRLTNTDIVALQEEYDELKQKIAALKHILENHDALLNVIKDELSEIKKQFKQPRL SVIEEKISEIKIDKEVIVPSETVMLSLTQAGYIKRTSLRSFNASGKEEIGLKERDGVLKIIETNTQDYVMVFTNKGRYLL IPVHKLPDVKWKDLGQHVSQIVPIEEDERVVNCYTVSDFNDEHAIITATRQGMIKKSLLSGFKSTRTSKPLVAMKVKEGD ALISVMYVPANAASQCITLLTHRGMSLTYPMSELPDTGLRAAGIKAINLKDEDHVVLADHIQPQDTILIATQRGALKRIG FKVLQQAKRAQRGITLLKELKKQPHRVVAARVCHPEQSQYRLVSQQDEVTGLIKDIHLSEQYTNGSFVVDTNTFGEIEDL FVD >1674|N125K|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|125|adeS_N125K|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYKFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRIEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEIG >1675|R152K|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|152|adeS_R152K|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELKTPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRIEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEIG >1676|T153M|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|153|adeS_T153M|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRMPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRIEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEIG >1677|Q163STOP|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|163|adeS_Q163STOP|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG RL* >1678|H189Y|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|189|adeS_H189Y|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSYLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRIEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEIG >1679|I252S|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|252|adeS_I252S|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRSEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKGTIQYSNQGSKSVFTIKISMGHEEIG >1680|G336S|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379793.1|336|adeS_G336S|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeS|wt_coherence=TRUE MKSKLGISKQLFIALTIVNLSVTLFSVVLGYVIYNYAIEKGWISLSSFQQEDWTSFHFVDWIWLATVIFCGCIISLVIGM RLAKRFIVPINFLAEAAKKISHGDLSARAYDNRIHSAEMSELLYNFNDMAQKLEVSVKNAQVWNAAIAHELRTPITILQG RLQGIIDGVFKPDEVLFKSLLNQVEGLSHLVEDLRTLSLVENQQLRLNYELFDFKAVVEKVLKAFEDRLDQAKLIPELDL TSTPVYCDHRRIEQVLIALIDNAIRYSHAGKLKISSEVVSQNWILKIEDEGPGIATEFQDDLFKPFFRLEESRNKEFGGT GLGLAVVHAIIVALKSTIQYSNQGSKSVFTIKISMGHEEIG >1681|D20N|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|20|adeR_D20N|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVENDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQPIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTALDQDIDKVMALRIGADDFVVKPFNPNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGELMNHCMNDSDALERTVDSHVSKLRKKLEEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1682|P56S|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|56|adeR_P56S|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVEDDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQSIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTALDQDIDKVMALRIGADDFVVKPFNPNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGELMNHCMNDSDALERTVDSHVSKLRKKLEEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1683|A91V|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|91|adeR_A91V|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVEDDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQPIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTVLDQDIDKVMALRIGADDFVVKPFNPNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGELMNHCMNDSDALERTVDSHVSKLRKKLEEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1684|P116L|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|116|adeR_P116L|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVEDDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQPIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTALDQDIDKVMALRIGADDFVVKPFNLNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGELMNHCMNDSDALERTVDSHVSKLRKKLEEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1685|L192R|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|192|adeR_L192R|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVEDDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQPIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTALDQDIDKVMALRIGADDFVVKPFNPNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGERMNHCMNDSDALERTVDSHVSKLRKKLEEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1686|E219A|NA|NA|NA|NA|NA|NA|NA|NA|Acinetobacter_baumannii|WP_031379794.1|219|adeR_E219A|EFFLUX|EFFLUX|Acinetobacter_baumannii_efflux_resistant_AdeR|wt_coherence=TRUE MFDHSFSFDCQDKIILVVEDDYDIGDIIENYLKREGMSVIRAMNGKQAIELHASQPIDLILLDIKLPELNGWEVLNKIRQ KAQTPVIMLTALDQDIDKVMALRIGADDFVVKPFNPNEVIARVQAVLRRTQFANKAANKNKLYKNIEIDTDTHSVYIHSE NKKILLNLTLTEYKIISFMIDQPHKVFTRGELMNHCMNDSDALERTVDSHVSKLRKKLAEQGIFQMLVNVRGVGYRLDNP LAIKDDA >1687|P601L|NA|NA|NA|NA|NA|NA|NA|NA|Streptococcus_pyogenes|WP_032462817.1|601|pbp2x_P601L|BETA-LACTAM|BETA-LACTAM|Streptococcus_pyogenes_beta-lactam_resistant_Pbp2x|wt_coherence=TRUE MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTI YDRNGTAIAVDSTTYSIYAILDKSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQK DRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGL ENTNYKWYSALHQGNFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFVFSS NVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAFTAISNNGEMLE PQFISQIYDPNTASFRTANKEVVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSED GSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGLLFWQDVVNPVLEEAYLMQDTLTKPVVSDANRQTTYKLPN FVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISF KGTDSGRVMKQSVDVGKSLKKIKKMTITLGD >1688|I355T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|355|parE_I355T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFTLWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1689|L416F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|416|parE_L416F|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFFVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1690|G423R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|423|parE_G423R|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSARGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1691|P439S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|439|parE_P439S|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMSLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1692|I444F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|444|parE_I444F|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKFLNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1693|L445H|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|445|parE_L445H|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKIHNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1694|S458A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|458|parE_S458A|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLAAQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1695|S458T|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|458|parE_S458T|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLATQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1696|E460D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|460|parE_E460D|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQDVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1697|E460K|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|460|parE_E460K|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQKVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1698|I464F|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|464|parE_I464F|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDFSVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1699|I470M|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|470|parE_I470M|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGMDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1700|D475E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|475|parE_D475E|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSEDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1701|D476N|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|476|parE_D476N|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDNLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1702|I529L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_033554192.1|529|parE_I529L|QUINOLONE|QUINOLONE|Escherichia_quinolone_resistant_ParE|wt_coherence=TRUE MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQHRMRAAKKVVRKKLTSGPALPGK LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRLDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV >1703|S83I|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|84|gyrA_S83I|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDIAIYESMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1704|S83L|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|84|gyrA_S83L|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDLAIYESMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1705|S83N|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|84|gyrA_S83N|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDNAIYESMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1706|S83R|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|84|gyrA_S83R|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDRAIYESMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1707|S83Y|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|84|gyrA_S83Y|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDYAIYESMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1708|E87G|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|88|gyrA_E87G|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDSAIYGSMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1709|E87K|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|88|gyrA_E87K|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDSAIYKSMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1710|E87L|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|88|gyrA_E87L|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDSAIYLSMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1711|E87Y|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecalis|WP_033785346.1|88|gyrA_E87Y|QUINOLONE|QUINOLONE|Enterococcus_faecalis_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIKENIQDVNLTSEMKESFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARIVGDVMGKYHP HGDSAIYYSMVRMAQPFSYRAMLVDGHGNFGSVDGDGAAAMRYTEARMSKIALEMLRDINKNTVDFQGNYDDSEQEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVIDATSLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVELTEMPNGKERILVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVIDVRRDVSASVVLNNL YKMTALQTSFGFNMLAIEKGVPKILSLKRILENYVEHQKEVITRRTIFDKNKAEARAHILEGLRIALDHIDEIIAIIRGS QSDDEAKATLIERFEFSDRQAQAILDMRLRRLTGLERDKIENEYQELLKFIADLEDILARPERVIEIIKTELNDVRTKFG DARRTELLVGEVLSLEDEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFF TNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAEKIQAIISVEGKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLI AISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLRENDYVVGAAILDENKEVLVITENGY GKRTKASEYPVKGRGGKGIKTANITEKNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDGAK VVTMAVVEPEEVEEEIVEVVETTKNETTSETEE >1712|K43R|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_057042458.1|43|rpsL_K43R|AMINOGLYCOSIDE|STREPTOMYCIN|Campylobacter_streptomycin_resistant_RpsL|wt_coherence=TRUE MPTINQLVRKERKKVLEKSKSPALKNCPQRRGVCTRVYTTTPRKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIV LVRGGRVKDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRSKAGAAK >1713|K88E|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_057042458.1|88|rpsL_K88E|AMINOGLYCOSIDE|STREPTOMYCIN|Campylobacter_streptomycin_resistant_RpsL|wt_coherence=TRUE MPTINQLVRKERKKVLEKSKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIV LVRGGRVEDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRSKAGAAK >1714|K88Q|NA|NA|NA|NA|NA|NA|NA|NA|Campylobacter|WP_057042458.1|88|rpsL_K88Q|AMINOGLYCOSIDE|STREPTOMYCIN|Campylobacter_streptomycin_resistant_RpsL|wt_coherence=TRUE MPTINQLVRKERKKVLEKSKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIV LVRGGRVQDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRSKAGAAK >1715|R620C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_086259262.1|620|acrB_R620C|TETRACYCLINE|TIGECYCLINE|Escherichia_tigecycline_resistant_AcrB|wt_coherence=TRUE MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEITHYYLTKEKNNVESVFAVNGFGFAGCGQNTGIAFVSLKDWADRPGE ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI EHSHTVDHH >1716|R15C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|15|nfsA_R15C|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSICHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1717|S33R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|33|nfsA_S33R|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINRARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1718|G131D|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|131|nfsA_G131D|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGDLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1719|R133S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|133|nfsA_R133S|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLSNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1720|K141STOP|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|141|nfsA_K141STOP|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVT* >1721|R203C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|203|nfsA_R203C|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTCGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1722|R203L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_089631889.1|203|nfsA_R203L|NITROFURAN|NITROFURANTOIN|Escherichia_nitrofurantoin_resistant_NfsA|wt_coherence=TRUE MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQYSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTLGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR >1723|G15R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|15|basR_G15R|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQRLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1724|S39I|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|39|basR_S39I|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQILEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1725|G53A|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53A|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLALPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1726|G53C|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53C|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLCLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1727|G53E|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53E|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLELPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1728|G53R|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53R|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLRLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1729|G53S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53S|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLSLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1730|G53V|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53V|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLVLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1731|G53W|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|53|basR_G53W|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLWLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1732|R81L|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|81|basR_R81L|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA LDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1733|R81S|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|81|basR_R81S|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA SDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1734|L105P|NA|NA|NA|NA|NA|NA|NA|NA|Escherichia|WP_094970923.1|105|basR_L105P|COLISTIN|COLISTIN|Escherichia_colistin_resistant_BasR|wt_coherence=TRUE MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA RDTLTDKIAGLDVGADDYLVKPFAPEELHARIRALLRSHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN >1735|S80I|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_101982161.1|80|parC_S80I|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDI ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTVDWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDELLDIVQGPDFPTEAEIITSRAEIRKIYQNGRGSVR MRAVWSKEDGAVVISALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNHRLEKVLKRLHILEGLLVAFLNIDEVIEIIRTEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQAILASERKMNNLLKKELQADADAFGDDRRSPL HEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAQGLSYKAGDSWKASAKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPDNAHVMPPLVIEDES DMLLAITAAGRMLMFPVSDLPQLSKGKGNKIISIPAAVMASSISDSSSI >1736|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_101982161.1|84|parC_E84K|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_ParC|wt_coherence=TRUE MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS ACYKAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTVDWVPNFDGTLQEPKMLPAR LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDELLDIVQGPDFPTEAEIITSRAEIRKIYQNGRGSVR MRAVWSKEDGAVVISALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTD LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNHRLEKVLKRLHILEGLLVAFLNIDEVIEIIRTEDEPK PALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQAILASERKMNNLLKKELQADADAFGDDRRSPL HEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAQGLSYKAGDSWKASAKGKSNQPVVFIDTTGRSYAIDPITL PSARGQGEPLTGKLTLPPGATVEHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPDNAHVMPPLVIEDES DMLLAITAAGRMLMFPVSDLPQLSKGKGNKIISIPAAVMASSISDSSSI >1737|S84A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|84|gyrA_S84A|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDASIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1738|S84L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|84|gyrA_S84L|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDLSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1739|S84W|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|84|gyrA_S84W|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDWSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1740|S85A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|85|gyrA_S85A|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDSAIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1741|E88G|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|88|gyrA_E88G|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDSSIYGAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1742|E88K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_pseudintermedius|WP_103263503.1|88|gyrA_E88K|QUINOLONE|QUINOLONE|Staphylococcus_pseudintermedius_quinolone_resistant_GyrA|wt_coherence=TRUE MAETSESRINERNISKEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHP HGDSSIYKAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKLALELLRDINKDTIDFIDNYDGNEREPSVL PSRFPNLLVNGASGIAVGMATNIPPHNMREVIDGVLSLSHNPDITISELMEDIQGPDFPTAGLILGKSGIRRAYETGRGS VIMRAKAEIESRGGGRDRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNN LYKQTPLQTSFGVNMIALVNGRPQLINLKQALYHYLEHQKEVVRRRTEYNLRKAKDRAHILEGLRIALDHIDEIITIIRE SETDKVAMESLQSRFALSERQAQAILDMRLRRLTGLERDKIEQEYNDLIAYIAELEAILADEEKLLELVREELTEIKEKF GDDRRTEIQLGGIDQLEDEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNTLDDDFVSQLVTTSTHDHVLF FTNKGRVYKLKGYEVPELSRQSKGIPIVNVIELDQDEVISTMIAVKDLDSEEDFLVFVTKKGLIKRSALSNFNRINRNGK IAIKFRDDDELIAVRLTDGEKHILIGTAQASLIRFKETDVRAMSRIAAGVKGIRLRDGDEVIGLDVADDDNQDEILVVTE KGYGKRTSIEDYRLSNRGGMGVKTAKLTERNGRLVCITTVEGDEDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDE EQYVSTVAKVKKEPEDIEADEHTTASEASDDVEVVVDDVTPGDTIHTEAPEPEVSPERETLREDFMDRVNEDIENEDK >1743|G61V|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|61|mprF_G61V|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGVASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1744|S295L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|295|mprF_S295L|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSLFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1745|P314L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|314|mprF_P314L|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFILAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1746|S337L|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|337|mprF_S337L|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLLLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1747|L341S|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|341|mprF_L341S|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAISVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1748|T345A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|345|mprF_T345A|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFASMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1749|T345I|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|345|mprF_T345I|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFISMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1750|T345K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|345|mprF_T345K|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFKSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1751|M347R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|347|mprF_M347R|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSRIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1752|V351E|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|351|mprF_V351E|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFEKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1753|I420N|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|420|mprF_I420N|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYNLITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1754|T472K|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|472|mprF_T472K|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGKLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK >1755|L826F|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_111724484.1|826|mprF_L826F|LIPOPEPTIDE|DAPTOMYCIN|Staphylococcus_aureus_daptomycin_resistant_MprF|wt_coherence=TRUE MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKM DISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALS GLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTS FLMSYQKDIIAKIPSLSLAILVFFTSMIFFVKNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIF AMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYT IEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLM YRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKR RGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLM PTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQ GLRRYKSKYNPNWEPRFLVYRKDNSFWESLSKVMRVIRHK >1756|S80I|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_115256011.1|82|parC_S80I|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_ParC|wt_coherence=FALSE MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPIG DSSIYEAMVRMSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPTGGILQGKDEIKKAYETGRGKVI LRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMDEIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFK NTELQINYNFNMVAIDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVIATIRESKD KKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQITELNKILSNDKELFSVMKKELREVKKNYSSA RLTTTEDEIEEIKIDTQVLVAQEDVIVSVTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANV IYRPVHELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTEFEPWRTYKSRPLSCMK LKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVVGAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQR GAVKRMLAQEISQTSRAKRGVTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEKKG GEVIEVIDAPEIFIES >1757|S80R|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_115256011.1|82|parC_S80R|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_ParC|wt_coherence=FALSE MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPRG DSSIYEAMVRMSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPTGGILQGKDEIKKAYETGRGKVI LRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMDEIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFK NTELQINYNFNMVAIDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVIATIRESKD KKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQITELNKILSNDKELFSVMKKELREVKKNYSSA RLTTTEDEIEEIKIDTQVLVAQEDVIVSVTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANV IYRPVHELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTEFEPWRTYKSRPLSCMK LKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVVGAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQR GAVKRMLAQEISQTSRAKRGVTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEKKG GEVIEVIDAPEIFIES >1758|E84A|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_115256011.1|86|parC_E84A|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_ParC|wt_coherence=FALSE MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHG DSAIYEAMVRMSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPTGGILQGKDEIKKAYETGRGKVI LRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMDEIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFK NTELQINYNFNMVAIDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVIATIRESKD KKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQITELNKILSNDKELFSVMKKELREVKKNYSSA RLTTTEDEIEEIKIDTQVLVAQEDVIVSVTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANV IYRPVHELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTEFEPWRTYKSRPLSCMK LKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVVGAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQR GAVKRMLAQEISQTSRAKRGVTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEKKG GEVIEVIDAPEIFIES >1759|E84K|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_115256011.1|86|parC_E84K|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_ParC|wt_coherence=FALSE MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHG DSKIYEAMVRMSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPTGGILQGKDEIKKAYETGRGKVI LRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMDEIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFK NTELQINYNFNMVAIDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVIATIRESKD KKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQITELNKILSNDKELFSVMKKELREVKKNYSSA RLTTTEDEIEEIKIDTQVLVAQEDVIVSVTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANV IYRPVHELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTEFEPWRTYKSRPLSCMK LKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVVGAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQR GAVKRMLAQEISQTSRAKRGVTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEKKG GEVIEVIDAPEIFIES >1760|E84T|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_115256011.1|86|parC_E84T|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_ParC|wt_coherence=FALSE MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHG DSTIYEAMVRMSQDWKLREVLIEMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPTGGILQGKDEIKKAYETGRGKVI LRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMDEIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFK NTELQINYNFNMVAIDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVIATIRESKD KKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQITELNKILSNDKELFSVMKKELREVKKNYSSA RLTTTEDEIEEIKIDTQVLVAQEDVIVSVTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANV IYRPVHELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTEFEPWRTYKSRPLSCMK LKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVVGAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQR GAVKRMLAQEISQTSRAKRGVTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEKKG GEVIEVIDAPEIFIES >1761|S83F|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|83|gyrA_S83F|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDFAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1762|S83I|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|83|gyrA_S83I|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDIAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1763|S83L|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|83|gyrA_S83L|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDLAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1764|S83T|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|83|gyrA_S83T|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDTAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1765|S83Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|83|gyrA_S83Y|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDYAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1766|D87A|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|87|gyrA_D87A|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYATIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1767|D87G|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|87|gyrA_D87G|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYGTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1768|D87H|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|87|gyrA_D87H|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYHTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1769|D87N|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|87|gyrA_D87N|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1770|D87Y|NA|NA|NA|NA|NA|NA|NA|NA|Klebsiella|WP_117036963.1|87|gyrA_D87Y|QUINOLONE|QUINOLONE|Klebsiella_quinolone_resistant_GyrA|wt_coherence=TRUE MSDLAREITPVNIEEELKNSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH GDSAVYYTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMP TKIPNLLVNGASGIAVGMATNIPPHNLTEVINGCLAYVDDEDISIEGLMAHIPGPDFPTAAIINGRRGIEEAYRTGRGKV YIRARAEVEVDAKSGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRRA PTPAEAKTALVAQAWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE LLEQIAELLHILGSADRLMEVIREELELIRDQFGDERRTEITANSADINIEDLINQEDVVVTLSHQGYVKYQPLTDYEAQ RRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEADERITAILPVREY EEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDAVRAMGRTATG VRGIKLAENDSVVSLIIPRGEGAILTVTQNGYGKRTAAAEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITD AGTLVRTRVSEVSIVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSAAEGDDDFAPEADTDDDIAEDEE >1771|E183A|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_123090655.1|183|pbp4_E183A|BETA-LACTAM|CEPHALOSPORIN|Staphylococcus_aureus_cephalosporin_resistant_Pbp4|wt_coherence=TRUE MKKLISIIIILCLTLSIMTPYAQATNSDVTPVQAANQYGYAGLSAAYEPTSAVNVSQTGQLLYQYNIDTKWNPASMTKLM TMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSNTKLYPGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVD LMNNKAKAIGMKNTHFVNPTGAANSRLRTFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTTHAVTYYT FNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKI LSKGEQRINGKKYYVENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINKDYGPPTVEVHQPIIQKANTVAKSMWEEH PLFTIIGGTCLVAGLALIVHMIINRLFRKRK >1772|F241R|NA|NA|NA|NA|NA|NA|NA|NA|Staphylococcus_aureus|WP_123090655.1|241|pbp4_F241R|BETA-LACTAM|CEPHALOSPORIN|Staphylococcus_aureus_cephalosporin_resistant_Pbp4|wt_coherence=TRUE MKKLISIIIILCLTLSIMTPYAQATNSDVTPVQAANQYGYAGLSAAYEPTSAVNVSQTGQLLYQYNIDTKWNPASMTKLM TMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSNTKLYPGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVD LMNNKAKAIGMKNTHFVNPTGAENSRLRTFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTTHAVTYYT RNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKI LSKGEQRINGKKYYVENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINKDYGPPTVEVHQPIIQKANTVAKSMWEEH PLFTIIGGTCLVAGLALIVHMIINRLFRKRK >1773|S83I|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|84|gyrA_S83I|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDIAIYESMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1774|S83L|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|84|gyrA_S83L|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDLAIYESMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1775|S83N|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|84|gyrA_S83N|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDNAIYESMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1776|S83R|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|84|gyrA_S83R|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDRAIYESMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1777|S83Y|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|84|gyrA_S83Y|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDYAIYESMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1778|E87G|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|88|gyrA_E87G|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDSAIYGSMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1779|E87K|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|88|gyrA_E87K|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDSAIYKSMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1780|E87L|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|88|gyrA_E87L|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDSAIYLSMVRMAQPFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE >1781|S97N|NA|NA|NA|NA|NA|NA|NA|NA|Enterococcus_faecium|WP_137277832.1|98|gyrA_S97N|QUINOLONE|QUINOLONE|Enterococcus_faecium_quinolone_resistant_GyrA|wt_coherence=TRUE MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHP HGDSAIYESMVRMAQPFNYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDFPTGGLVMGKSGIRRAYETGKGS ITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIERISELHRDKRIEGITDLRDESSREGMRIVVDIRRDASASVILNNL YKLTSLQNSFGFNMLAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDEIIAIIRGS KSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKLIEDLTDILARPERVTEIIKNELADLNQRFG DKRRTELLVGEVLSLEDEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFF TNNGKVYRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVKRTSVTAFANIRSNGLI AIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDMGRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGY GKRTKVSEYPVKGRGGKGIKTANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEADTK VVTMAAVEPEAAEQTVEEQGSEE