Drivers of human diseases including environmental, maternal and social exposures. Disease Drivers The official definition. definition The official definition. url:http://purl.obolibrary.org/obo/iao.owl Description of the ontology. description Description of the ontology. url:http://purl.org/dc/elements/1.1/description Title of the ontology. title Title of the ontology. url:http://purl.org/dc/elements/1.1/title License of the ontology. license License of the ontology. url:http://purl.org/dc/terms/license Reference database or publication source. database_cross_reference Reference database or publication source. url:http://www.geneontology.org/formats/oboInOwl#hasDbXref has exact synonym An identifier for an individual entity. id An identifier for an individual entity. url:http://purl.obolibrary.org/obo/IAO_0020000 A human readable name for this class. label A human readable name for this class. url:http://www.w3.org/2000/01/rdf-schema#label part of has part has role A relation between two entities, in which one of the entities is any natural or human-influenced factor that directly or indirectly causes a change in the other entity. has_driver A relation between two entities, in which one of the entities is any natural or human-influenced factor that directly or indirectly causes a change in the other entity. url:http://purl.obolibrary.org/obo/RO_0007000 lead A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. CHEBI:30879 alcohol A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. url:https://medlineplus.gov/alcohol.html A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. CHEBI:50904 allergen A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. url:https://www.niehs.nih.gov/health/topics/agents/allergens/ thalidomide Environmental or genetic mechanisms driving the occurrance of complex diseases. DISDRIV:0000000 disease driver Environmental or genetic mechanisms driving the occurrance of complex diseases. url:https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4517741/ A disease driver that is comprised of a shortage of a nutrient. DISDRIV:0000001 nutrient deficiency A disease driver that is comprised of a shortage of a nutrient. url:https://www.who.int/health-topics/micronutrients A disease driver that is related to or concerning the interaction of social and economic factors. DISDRIV:0000002 socioeconomic driver A disease driver that is related to or concerning the interaction of social and economic factors. url:https://pubmed.ncbi.nlm.nih.gov/29709281/ A disease driver that is of biological origin. DISDRIV:0000003 biological driver A disease driver that is of biological origin. url:https://www.ncbi.nlm.nih.gov/books/NBK45737/ A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. DISDRIV:0000004 deficiency of biotin A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. url:https://ods.od.nih.gov/factsheets/Biotin-Consumer/ A nutrient deficiency. DISDRIV:0000005 deficiency of choline A nutrient deficiency. url:https://ods.od.nih.gov/factsheets/Choline-Consumer/ url:url:https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ A disease driver that is a chemical. DISDRIV:0000006 chemical driver A disease driver that is a chemical. url:https://pubmed.ncbi.nlm.nih.gov/29351546/ DISDRIV:0000007 deficiency of vitamin C An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. ExO:0000007 ecological perturbations An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. url:https://pubmed.ncbi.nlm.nih.gov/29351546/ An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. ENVO:03000127 OMIT:0016047 ExO:0000013 acid rain An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. url:https://pubmed.ncbi.nlm.nih.gov/29351546/ url:https://www.epa.gov/acidrain/what-acid-rain An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. ExO:0000014 climate change An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. url:https://pubmed.ncbi.nlm.nih.gov/29351546/ A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. ExO:0000015 poverty A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. url:https://en.wikipedia.org/wiki/Poverty url:https://www.un.org/en/global-issues/ending-poverty url:https://www.worldbank.org/en/topic/poverty/overview An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. FOODON:00001579 alcoholic beverage An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. url:https://en.m.wikipedia.org/wiki/Alcoholic_drink A biological driver that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. NCIT:C163032 botulinum toxin A biological driver that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. url:https://www.osha.gov/botulism