The Disease Ontology has been developed as a standardized ontology for human disease with the purpose of providing the biomedical community with consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related medical vocabulary disease concepts. Human Disease Ontology 27:11:2024 11:39 disease_ontology 1.2 lschriml The Disease Ontology content is available via the Creative Commons Public Domain Dedication CC0 1.0 Universal license (https://creativecommons.org/publicdomain/zero/1.0/). 2024-11-27 definition Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007. definition source Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007. url:http://purl.obolibrary.org/obo/iao.owl Has ontology root term. has_ontology_root_term Has ontology root term. url:http://purl.obolibrary.org/obo/IAO_0000700 Use on obsolete terms, relating the term to another term that can be used as a substitute. term replaced by Use on obsolete terms, relating the term to another term that can be used as a substitute. url:https://www.ebi.ac.uk/ols/ontologies/iao/properties?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FIAO_0100001 acronym DO_AGR_slim DO_AGR_slim DO_CFDE_slim DO_CFDE_slim DO_FlyBase_slim DO_FlyBase_slim DO_GXD_slim DO_GXD_slim DO_IEDB_slim DO_IEDB_slim DO_MGI_slim DO_MGI_slim DO_RAD_slim DO_RAD_slim DO_cancer_slim DO_cancer_slim DO_childhood_cancer_slim DO_childhood_cancer_slim DO_infectious_disease_slim DO_infectious_disease_slim DO_rare_slim DO_rare_slim GOLD GOLD NCIthesaurus NCIthesaurus TopNodes_DOcancerslim TopNodes_DOcancerslim gram-negative_bacterial_infectious_disease gram-negative_bacterial_infectious_disease gram-positive_bacterial_infectious_disease gram-positive_bacterial_infectious_disease sexually_transmitted_infectious_disease sexually_transmitted_infectious_disease tick-borne_infectious_disease tick-borne_infectious_disease zoonotic_infectious_disease zoonotic_infectious_disease dc:date Description. description Description. url:http://purl.org/dc/elements/1.1/description Title. title Title. url:http://purl.org/dc/elements/1.1/title The dc:type. dc:type The dc:type. url:http://purl.org/dc/elements/1.1/type License. license License. url:http://purl.org/dc/terms/license Subset property, name of subet. subset_property Subset property, name of subet. url:http://www.geneontology.org/formats/oboInOwl#SubsetProperty synonym_type_property auto-generated-by Author of the class. created_by Author of the class. url:http://www.geneontology.org/formats/oboInOwl#created_by Date class was created. creation_date Date class was created. url:http://www.geneontology.org/formats/oboInOwl#creation_date Date. date Date. url:http://purl.org/dc/elements/1.1/date Default namespace. default-namespace Default namespace. url:http://www.geneontology.org/formats/oboInOwl#default-namespace ID of merged class. has_alternative_id ID of merged class. url:http://www.geneontology.org/formats/oboInOwl#hasAlternativeId Broad synonym. has_broad_synonym Broad synonym. url:http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym Reference database or publication source. database_cross_reference Reference database or publication source. url:http://www.geneontology.org/formats/oboInOwl#hasDbXref Exact synonym. has_exact_synonym Exact synonym. url:http://www.geneontology.org/formats/oboInOwl#hasExactSynonym Narrow synonym. has_narrow_synonym Narrow synonym. url:http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym Has OBO format version. has_obo_format_version Has OBO format version. url:http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion Name space of the ontology. disease_ontology has_obo_namespace Name space of the ontology. url:http://www.geneontology.org/formats/oboInOwl#hasOBONamespace Has related synonym. has_related_synonym Has related synonym. url:http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym has_synonym_type An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity. id An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity. url:http://purl.obolibrary.org/obo/IAO_0020000 In subset. in_subset In subset. url:http://www.geneontology.org/formats/oboInOwl#inSubset Saved by. saved-by Saved by. url:http://www.geneontology.org/formats/oboInOwl#saved-by Comment. comment Comment. url:http://www.w3.org/2000/01/rdf-schema#comment Is defined by. rdfs:isDefinedBy Is defined by. url:http://www.w3.org/2000/01/rdf-schema#isDefinedBy A human readable name for this class. A human readable name for this class. url:http://www.w3.org/2000/01/rdf-schema#label url:https://www.w3.org/TR/owl-guide/ OWL deprecated. owl:deprecated OWL deprecated. url:http://www.w3.org/2002/07/owl#deprecated Version info. owl:versionInfo Version info. url:http://www.w3.org/2002/07/owl#versionInfo A skos concept mapping used to state a hierarchical mapping link between two concepts where the DO concept is broad and the xref is narrow (represents subtypes). has broader match A skos concept mapping used to state a hierarchical mapping link between two concepts where the DO concept is broad and the xref is narrow (represents subtypes). url:https://www.w3.org/2009/08/skos-reference/skos.html#broadMatch A skos concept mapping used to link two concepts that are sufficiently similar that they can be used interchangeably. has close match A skos concept mapping used to link two concepts that are sufficiently similar that they can be used interchangeably. url:https://www.w3.org/2009/08/skos-reference/skos.html#closeMatch A skos concept mapping used to link two concepts, indicating a high degree of confidence that the concepts can be used interchangeably. has exact match A skos concept mapping used to link two concepts, indicating a high degree of confidence that the concepts can be used interchangeably. url:https://www.w3.org/2009/08/skos-reference/skos.html#exactMatch A skos concept mapping used to state a hierarchical mapping link between two concepts where the DO concept is narrow (DO represents subtypes) and the xref is broad. has narrower match A skos concept mapping used to state a hierarchical mapping link between two concepts where the DO concept is narrow (DO represents subtypes) and the xref is broad. url:https://www.w3.org/2009/08/skos-reference/skos.html#narrowMatch A skos concept mapping used to state an associative mapping link between two concepts. has related match A skos concept mapping used to state an associative mapping link between two concepts. https://www.w3.org/2009/08/skos-reference/skos.html#relatedMatch Relating the disease to it’s causation (disease and disorder). has material basis in Relating the disease to it’s causation (disease and disorder). url:http://purl.obolibrary.org/obo/IDO_0000664 Relation defining child to partent inheritance type. disease_ontology is_a Relation defining child to partent inheritance type. url:http://geneontology.org/docs/ontology-relations/ url:http://purl.obolibrary.org/obo/rex#is_a A vascular cancer that derives_from the cells that line the walls of blood vessels or lymphatic vessels. DOID:267 DOID:4508 ICDO:9120/3 MESH:D006394 NCI:C3088 NCI:C9275 SNOMEDCT_US_2023_03_01:39000009 UMLS_CUI:C0018923 UMLS_CUI:C0854893 hemangiosarcoma disease_ontology DOID:0001816 angiosarcoma A vascular cancer that derives_from the cells that line the walls of blood vessels or lymphatic vessels. url:http://en.wikipedia.org/wiki/Hemangiosarcoma url:https://en.wikipedia.org/wiki/Angiosarcoma url:https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C3088 url:https://www.ncbi.nlm.nih.gov/pubmed/23327728 A corneal disease that is characterized by a triangular tissue growth located_in cornea of the eye that is the result of collagen degeneration and fibrovascular proliferation. laronhughes 2010-06-30T02:44:30Z UMLS_CUI:C0033999 surfer's eye disease_ontology DOID:0002116 pterygium A corneal disease that is characterized by a triangular tissue growth located_in cornea of the eye that is the result of collagen degeneration and fibrovascular proliferation. url:https://en.wikipedia.org/wiki/Pterygium_(conjunctiva) A disease that involving errors in metabolic processes of building or degradation of molecules. ICD10CM:E88.9 ICD9CM:277.9 MESH:D008659 NCI:C3235 SNOMEDCT_US_2023_03_01:75934005 UMLS_CUI:C0025517 metabolic disease disease_ontology DOID:0014667 disease of metabolism A disease that involving errors in metabolic processes of building or degradation of molecules. url:http://www.ncbi.nlm.nih.gov/books/NBK22259/ A crustacean allergy that has_allergic_trigger shrimp. disease_ontology DOID:0040001 shrimp allergy A crustacean allergy that has_allergic_trigger shrimp. url:https://www.ncbi.nlm.nih.gov/pubmed/20471069 IEDB:RV A drug allergy that has_allergic_trigger acetylsalicylic acid. SNOMEDCT_US_2023_03_01:293586001 UMLS_CUI:C0004058 ASA allergy acetylsalicylic acid allergy disease_ontology DOID:0040002 aspirin allergy A drug allergy that has_allergic_trigger acetylsalicylic acid. url:https://www.ncbi.nlm.nih.gov/pubmed/2468301 IEDB:RV A beta-lactam allergy that has_allergic_trigger benzylpenicillin. SNOMEDCT_US_2023_03_01:294499007 UMLS_CUI:C0571411 benzyl penicillin allergy penicillin G allergy disease_ontology DOID:0040003 benzylpenicillin allergy A beta-lactam allergy that has_allergic_trigger benzylpenicillin. url:https://www.ncbi.nlm.nih.gov/pubmed/14483916 IEDB:RV A beta-lactam allergy that has_allergic_trigger amoxicillin. SNOMEDCT_US_2023_03_01:294505008 UMLS_CUI:C0571417 disease_ontology DOID:0040004 amoxicillin allergy A beta-lactam allergy that has_allergic_trigger amoxicillin. url:https://www.ncbi.nlm.nih.gov/pubmed/11746950 IEDB:RV A cephalosporin allergy that has_allergic_trigger ceftriaxone. SNOMEDCT_US_2023_03_01:294551009 UMLS_CUI:C0571463 rocephin allergy disease_ontology DOID:0040005 ceftriaxone allergy A cephalosporin allergy that has_allergic_trigger ceftriaxone. url:https://www.ncbi.nlm.nih.gov/pubmed/12833570 IEDB:RV A drug allergy that has_allergic_trigger carbamazepine. SNOMEDCT_US_2023_03_01:293867002 UMLS_CUI:C0570787 Tegretol allergy carbamazepen allergy disease_ontology DOID:0040006 carbamazepine allergy A drug allergy that has_allergic_trigger carbamazepine. url:https://www.ncbi.nlm.nih.gov/pubmed/7602118 IEDB:RV A drug allergy that has_allergic_trigger abacavir. ABC allergy disease_ontology DOID:0040007 abacavir allergy A drug allergy that has_allergic_trigger abacavir. url:https://www.ncbi.nlm.nih.gov/pubmed/25674793 IEDB:RV A drug allergy that has_allergic_trigger isoniazide. ICD10CM:Z88.1 INH allergy isonicotinylhydrazide allergy disease_ontology DOID:0040008 isoniazide allergy A drug allergy that has_allergic_trigger isoniazide. url:https://www.ncbi.nlm.nih.gov/pubmed/445303 IEDB:RV A drug allergy that has_allergic_trigger lidocaine. SNOMEDCT_US_2023_03_01:293722000 UMLS_CUI:C0570646 Lidoderm allergy lignocaine allergy xylocaine allergy disease_ontology DOID:0040009 lidocaine allergy A drug allergy that has_allergic_trigger lidocaine. url:https://www.ncbi.nlm.nih.gov/pubmed/9013953 IEDB:RV A drug allergy that has_allergic_trigger mepivacaine. ICD10CM:Z88.4 Carbocaine allergy Polocaine allergy disease_ontology DOID:0040010 mepivacaine allergy A drug allergy that has_allergic_trigger mepivacaine. url:https://www.ncbi.nlm.nih.gov/pubmed/9989796 IEDB:RV A drug allergy that has_allergic_trigger phenobarbital. SNOMEDCT_US_2023_03_01:293865005 UMLS_CUI:C0570785 Luminal allergy phenobarbitol allergy phenobarbitone allergy disease_ontology DOID:0040011 phenobarbital allergy A drug allergy that has_allergic_trigger phenobarbital. url:https://www.ncbi.nlm.nih.gov/pubmed/11994495 IEDB:RV A drug allergy that has_allergic_trigger phenytoin. SNOMEDCT_US_2023_03_01:293869004 UMLS_CUI:C0570789 Dilantin allergy disease_ontology DOID:0040012 phenytoin allergy A drug allergy that has_allergic_trigger phenytoin. url:https://www.ncbi.nlm.nih.gov/pubmed/7602118 IEDB:RV A drug allergy that has_allergic_trigger ranitidine. SNOMEDCT_US_2023_03_01:293653009 UMLS_CUI:C0570577 Zantac allergy disease_ontology DOID:0040013 ranitidine allergy A drug allergy that has_allergic_trigger ranitidine. url:https://www.ncbi.nlm.nih.gov/pubmed/7782125 IEDB:RV A drug allergy that has_allergic_trigger corticosteroid. disease_ontology DOID:0040014 corticosteroid allergy A drug allergy that has_allergic_trigger corticosteroid. url:https://www.ncbi.nlm.nih.gov/pubmed/2265088 IEDB:RV A drug allergy that has_allergic_trigger sulfonamide. SNOMEDCT_US_2023_03_01:91939003 UMLS_CUI:C0038757 disease_ontology DOID:0040015 sulfonamide allergy A drug allergy that has_allergic_trigger sulfonamide. url:https://www.ncbi.nlm.nih.gov/pubmed/2434548 IEDB:RV A drug allergy that has_allergic_trigger sulfamethoxazole. SMX allergy SMZ allergy sulphamethoxazole allergy disease_ontology DOID:0040016 sulfamethoxazole allergy A drug allergy that has_allergic_trigger sulfamethoxazole. url:https://www.ncbi.nlm.nih.gov/pubmed/7602118 IEDB:RV A drug allergy that has_allergic_trigger suprofen. Profenal allergy disease_ontology DOID:0040017 suprofen allergy A drug allergy that has_allergic_trigger suprofen. url:https://www.ncbi.nlm.nih.gov/pubmed/509935 IEDB:RV A drug allergy that has_allergic_trigger thiopental. SNOMEDCT_US_2023_03_01:293709008 UMLS_CUI:C0570633 penthiobarbital allergy pentothiobarbital allergy disease_ontology DOID:0040018 thiopental allergy A drug allergy that has_allergic_trigger thiopental. url:https://www.ncbi.nlm.nih.gov/pubmed/2215478 IEDB:RV A drug allergy that has_allergic_trigger D-mannitol. SNOMEDCT_US_2023_03_01:295019008 UMLS_CUI:C0571922 mannitol allergy disease_ontology DOID:0040019 D-mannitol allergy A drug allergy that has_allergic_trigger D-mannitol. url:https://www.ncbi.nlm.nih.gov/pubmed/15479277 IEDB:RV A cephalosporin allergy that has_allergic_trigger cefotaxime. SNOMEDCT_US_2023_03_01:294545004 UMLS_CUI:C0571457 disease_ontology DOID:0040020 cefotaxime allergy A cephalosporin allergy that has_allergic_trigger cefotaxime. url:https://www.ncbi.nlm.nih.gov/pubmed/12833570 IEDB:RV A drug allergy that has_allergic_trigger cephalosporin. SNOMEDCT_US_2023_03_01:294532003 UMLS_CUI:C0571444 disease_ontology DOID:0040021 cephalosporin allergy A drug allergy that has_allergic_trigger cephalosporin. url:https://www.ncbi.nlm.nih.gov/pubmed/2083978 IEDB:RV A drug allergy that has_allergic_trigger amodiaquine. SNOMEDCT_US_2023_03_01:294390007 UMLS_CUI:C0571303 Camoquin allergy Flavoquine allergy disease_ontology DOID:0040022 amodiaquine allergy A drug allergy that has_allergic_trigger amodiaquine. url:https://www.ncbi.nlm.nih.gov/pubmed/1959977 IEDB:RV A cephalosporin allergy that has_allergic_trigger cefaclor. SNOMEDCT_US_2023_03_01:294541008 UMLS_CUI:C0571453 Ceclor allergy cephaclor allergy disease_ontology DOID:0040023 cefaclor allergy A cephalosporin allergy that has_allergic_trigger cefaclor. url:https://www.ncbi.nlm.nih.gov/pubmed/12569987 IEDB:RV A cephalosporin allergy that has_allergic_trigger ceftazidime. SNOMEDCT_US_2023_03_01:294546003 UMLS_CUI:C0571458 Fortaz allergy Tazicef allergy disease_ontology DOID:0040024 ceftazidime allergy A cephalosporin allergy that has_allergic_trigger ceftazidime. url:https://www.ncbi.nlm.nih.gov/pubmed/12833570 IEDB:RV A cephalosporin allergy that has_allergic_trigger cefuroxime. SNOMEDCT_US_2023_03_01:294542001 UMLS_CUI:C0571454 Zinacef allergy cephuroxime allergy disease_ontology DOID:0040025 cefuroxime allergy A cephalosporin allergy that has_allergic_trigger cefuroxime. url:https://www.ncbi.nlm.nih.gov/pubmed/12833570 IEDB:RV A drug allergy that has_allergic_trigger chlorhexidine. SNOMEDCT_US_2023_03_01:294431008 UMLS_CUI:C0571344 disease_ontology DOID:0040026 chlorhexidine allergy A drug allergy that has_allergic_trigger chlorhexidine. url:https://www.ncbi.nlm.nih.gov/pubmed/10848923 IEDB:RV A drug allergy that has_allergic_trigger cyclophosphamide. SNOMEDCT_US_2023_03_01:293748008 UMLS_CUI:C0570670 cytophosphane allergy disease_ontology DOID:0040027 cyclophosphamide allergy A drug allergy that has_allergic_trigger cyclophosphamide. url:https://www.ncbi.nlm.nih.gov/pubmed/8024619 IEDB:RV A drug allergy that has_allergic_trigger succinylcholine. SNOMEDCT_US_2023_03_01:294224007 UMLS_CUI:C0571140 dicholine succinate allergy succinocholine allergy sux allergy suxamethonium allergy disease_ontology DOID:0040028 succinylcholine allergy A drug allergy that has_allergic_trigger succinylcholine. url:https://www.ncbi.nlm.nih.gov/pubmed/2410473 IEDB:RV A drug allergy that has_allergic_trigger trimethoprim. SNOMEDCT_US_2023_03_01:294477004 UMLS_CUI:C0571390 Primsol allergy TMP allergy proloprim allergy disease_ontology DOID:0040029 trimethoprim allergy A drug allergy that has_allergic_trigger trimethoprim. url:https://www.ncbi.nlm.nih.gov/pubmed/3377143 IEDB:RV A cephalosporin allergy that has_allergic_trigger cefixime. SNOMEDCT_US_2023_03_01:294548002 UMLS_CUI:C0571460 disease_ontology DOID:0040030 cefixime allergy A cephalosporin allergy that has_allergic_trigger cefixime. url:https://www.ncbi.nlm.nih.gov/pubmed/16867046 IEDB:RV A drug allergy that has_allergic_trigger diclofenac. SNOMEDCT_US_2023_03_01:293613006 UMLS_CUI:C0570540 Voltaren allergy disease_ontology DOID:0040031 diclofenac allergy A drug allergy that has_allergic_trigger diclofenac. url:https://www.ncbi.nlm.nih.gov/pubmed/21060839 IEDB:RV A drug allergy that has_allergic_trigger carbapenems. SNOMEDCT_US_2023_03_01:294531005 UMLS_CUI:C0571443 disease_ontology DOID:0040032 carbapenem allergy A drug allergy that has_allergic_trigger carbapenems. url:https://www.ncbi.nlm.nih.gov/pubmed/2457043 IEDB:RV A beta-lactam allergy that has_allergic_trigger piperacillin. SNOMEDCT_US_2023_03_01:294515002 UMLS_CUI:C0571427 disease_ontology DOID:0040033 piperacillin allergy A beta-lactam allergy that has_allergic_trigger piperacillin. url:https://www.ncbi.nlm.nih.gov/pubmed/21532862 IEDB:RV A drug allergy that has_allergic_trigger rocuronium. SNOMEDCT_US_2023_03_01:294233009 UMLS_CUI:C0571149 Esmeron allergy Zemuron allergy disease_ontology DOID:0040034 rocuronium allergy A drug allergy that has_allergic_trigger rocuronium. url:https://www.ncbi.nlm.nih.gov/pubmed/17667569 IEDB:RV A drug allergy that has_allergic_trigger sulfasalazine. SNOMEDCT_US_2023_03_01:293663001 UMLS_CUI:C0570587 disease_ontology DOID:0040035 sulfasalazine allergy A drug allergy that has_allergic_trigger sulfasalazine. url:https://www.ncbi.nlm.nih.gov/pubmed/2434548 IEDB:RV A drug allergy that has_allergic_trigger tubocurarine. SNOMEDCT_US_2023_03_01:294231006 UMLS_CUI:C0571147 DTC allergy disease_ontology DOID:0040036 tubocurarine allergy A drug allergy that has_allergic_trigger tubocurarine. url:https://www.ncbi.nlm.nih.gov/pubmed/2215478 IEDB:RV A beta-lactam allergy that has_allergic_trigger aztreonam. SNOMEDCT_US_2023_03_01:294565006 UMLS_CUI:C0571476 Azactam allergy Primbactam allergy disease_ontology DOID:0040037 aztreonam allergy A beta-lactam allergy that has_allergic_trigger aztreonam. url:https://www.ncbi.nlm.nih.gov/pubmed/1991925 IEDB:RV An allergic asthma that has_allergic_trigger meropenem, a beta-lactam antibiotic. Merrem allergy disease_ontology DOID:0040038 meropenem allergy An allergic asthma that has_allergic_trigger meropenem, a beta-lactam antibiotic. url:https://www.ncbi.nlm.nih.gov/pubmed/23668298 IEDB:RV An isocyanates allergic asthma that has_allergic_trigger hexamethylene diisocyanate. allergic asthma to HDI allergic asthma to HMDI disease_ontology DOID:0040040 hexamethylene diisocyanate allergic asthma An isocyanates allergic asthma that has_allergic_trigger hexamethylene diisocyanate. url:https://www.ncbi.nlm.nih.gov/pubmed/8711735 IEDB:RV An allergic asthma that has_allergic_trigger isocyanates. disease_ontology DOID:0040041 isocyanates allergic asthma An allergic asthma that has_allergic_trigger isocyanates. url:https://www.ncbi.nlm.nih.gov/pubmed/3349596 IEDB:RV An isocyanates allergic asthma that has_allergic_trigger diphenylmethane-4,4-diisocyanate. allergic asthma to MDI disease_ontology DOID:0040042 diphenylmethane-4,4'-diisocyanate allergic asthma An isocyanates allergic asthma that has_allergic_trigger diphenylmethane-4,4-diisocyanate. url:https://www.ncbi.nlm.nih.gov/pubmed/8711735 IEDB:RV An isocyanates allergic asthma that has_allergic_trigger toluene meta-diisocyanate. allergic asthma to TDI disease_ontology DOID:0040043 toluene meta-diisocyanate allergic asthma An isocyanates allergic asthma that has_allergic_trigger toluene meta-diisocyanate. url:https://www.ncbi.nlm.nih.gov/pubmed/11289402 IEDB:RV An isocyanates allergic asthma that has_allergic_trigger methyl isocyanate. allergic asthma to MIC disease_ontology DOID:0040044 methyl isocyanate allergic asthma An isocyanates allergic asthma that has_allergic_trigger methyl isocyanate. url:https://www.ncbi.nlm.nih.gov/pubmed/3622432 IEDB:RV An allergic asthma that has_allergic_trigger nickel atom. allergic asthma to Ni disease_ontology DOID:0040045 nickel allergic asthma An allergic asthma that has_allergic_trigger nickel atom. url:https://www.ncbi.nlm.nih.gov/pubmed/6691936 IEDB:RV An allergic contact dermatitis that has_allergic_trigger nickel atom. ICD10CM:L23.0 allergic contact dermatitis to Ni disease_ontology DOID:0040046 nickel allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger nickel atom. url:https://www.ncbi.nlm.nih.gov/pubmed/7671317 IEDB:RV An allergic asthma that has_allergic_trigger trimellitic anhydride. allergic asthma to TMA disease_ontology DOID:0040047 trimellitic anhydride allergic asthma An allergic asthma that has_allergic_trigger trimellitic anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/6643876 IEDB:RV An allergic asthma that has_allergic_trigger phthalic anhydride. disease_ontology DOID:0040048 phthalic anhydride allergic asthma An allergic asthma that has_allergic_trigger phthalic anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/3711550 IEDB:RV An allergic asthma that has_allergic_trigger maleic anhydride. allergic asthma to MA disease_ontology DOID:0040049 maleic anhydride allergic asthma An allergic asthma that has_allergic_trigger maleic anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/3711550 IEDB:RV An allergic asthma that has_allergic_trigger tetrachlorophthalic anhydride. disease_ontology DOID:0040050 tetrachlorophthalic anhydride allergic asthma An allergic asthma that has_allergic_trigger tetrachlorophthalic anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/3711550 IEDB:RV An allergic asthma that has_allergic_trigger hexahydrophthalic anhydride. allergic asthma to HHPA disease_ontology DOID:0040051 hexahydrophthalic anhydride allergic asthma An allergic asthma that has_allergic_trigger hexahydrophthalic anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/4008795 IEDB:RV An allergic contact dermatitis that has_allergic_trigger diphenylmethane-4,4-diisocyanate. allergic contact dermatitis to MDI disease_ontology DOID:0040052 diphenylmethane-4,4'-diisocyanate allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger diphenylmethane-4,4-diisocyanate. url:https://www.ncbi.nlm.nih.gov/pubmed/6296214 IEDB:RV An allergic contact dermatitis that has_allergic_trigger cobalt atom. allergic contact dermatitis to Co disease_ontology DOID:0040053 cobalt allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger cobalt atom. url:https://www.ncbi.nlm.nih.gov/pubmed/8566016 IEDB:RV An allergic asthma that has_allergic_trigger cobalt atom. Co allergic asthma disease_ontology DOID:0040054 cobalt allergic asthma An allergic asthma that has_allergic_trigger cobalt atom. url:https://www.ncbi.nlm.nih.gov/pubmed/7444839 IEDB:RV An allergic contact dermatitis that has_allergic_trigger palladium. allergic contact dermatitis to Pd disease_ontology DOID:0040055 palladium allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger palladium. url:https://www.ncbi.nlm.nih.gov/pubmed/25097477 IEDB:RV An allergic contact dermatitis that has_allergic_trigger chromium atom. ICD10CM:L23.0 disease_ontology DOID:0040056 chromium allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger chromium atom. url:https://www.ncbi.nlm.nih.gov/pubmed/1108802 IEDB:RV An allergic contact dermatitis that has_allergic_trigger benzoic acid. SNOMEDCT_US_2023_03_01:294186000 UMLS_CUI:C0571102 allergic contact dermatitis to benzoate disease_ontology DOID:0040057 benzoic acid allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger benzoic acid. url:https://www.ncbi.nlm.nih.gov/pubmed/25097477 IEDB:RV An allergic contact dermatitis that has_allergic_trigger 1,4-phenylenediamine. allergic contact dermatitis to PPD allergic contact dermatitis to p-phenylenediamine disease_ontology DOID:0040058 1,4-phenylenediamine allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger 1,4-phenylenediamine. url:https://www.ncbi.nlm.nih.gov/pubmed/8400900 IEDB:RV An allergic contact dermatitis that has_allergic_trigger potassium dichromate. disease_ontology DOID:0040059 potassium dichromate allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger potassium dichromate. url:https://www.ncbi.nlm.nih.gov/pubmed/15462465 IEDB:RV A photoallergic dermatitis that has_allergic_trigger ketoprofen. SNOMEDCT_US_2023_03_01:293621000 UMLS_CUI:C0570547 photoallergic dermatitis to Orudis disease_ontology DOID:0040060 ketoprofen photoallergic dermatitis A photoallergic dermatitis that has_allergic_trigger ketoprofen. url:https://www.ncbi.nlm.nih.gov/pubmed/11169173 IEDB:RV A respiratory allergy that has_allergic_trigger remazole black-GR. respiratory allergy to Reactive Black 5 disease_ontology DOID:0040061 remazole black respiratory allergy A respiratory allergy that has_allergic_trigger remazole black-GR. url:https://www.ncbi.nlm.nih.gov/pubmed/2312995 IEDB:RV A respiratory allergy that has_allergic_trigger chloramine T. respiratory allergy to Chloraseptin respiratory allergy to Chlorazol respiratory allergy to Trichlorol disease_ontology DOID:0040062 chloramine T respiratory allergy A respiratory allergy that has_allergic_trigger chloramine T. url:https://www.ncbi.nlm.nih.gov/pubmed/2758361 IEDB:RV A respiratory allergy that has_allergic_trigger 4-vinylcyclohexene dioxide. respiratory allergy to vinyl cyclohexene diepoxide disease_ontology DOID:0040063 4-vinylcyclohexene dioxide respiratory allergy A respiratory allergy that has_allergic_trigger 4-vinylcyclohexene dioxide. url:https://www.ncbi.nlm.nih.gov/pubmed/3356477 IEDB:RV An allergic contact dermatitis that has_allergic_trigger (-)-carvone. allergic contact dermatitis to levo-carvone disease_ontology DOID:0040064 carvone allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger (-)-carvone. url:https://www.ncbi.nlm.nih.gov/pubmed/11380545 IEDB:RV A drug allergy that has_allergic_trigger quinidine. SNOMEDCT_US_2023_03_01:294978001 UMLS_CUI:C0571881 Kinidin allergy disease_ontology DOID:0040065 quinidine allergy A drug allergy that has_allergic_trigger quinidine. url:https://www.ncbi.nlm.nih.gov/pubmed/445303 IEDB:RV A drug allergy that has_allergic_trigger melphalan. SNOMEDCT_US_2023_03_01:293751001 UMLS_CUI:C0570673 Alkeran allergy disease_ontology DOID:0040066 melphalan allergy A drug allergy that has_allergic_trigger melphalan. url:https://www.ncbi.nlm.nih.gov/pubmed/445303 IEDB:RV An allergic contact dermatitis that has_allergic_trigger neomycin sulfate. SNOMEDCT_US_2023_03_01:409640001 UMLS_CUI:C1443961 allergic contact dermatitis to neomycin sulphate disease_ontology DOID:0040067 neomycin sulfate allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger neomycin sulfate. url:https://www.ncbi.nlm.nih.gov/pubmed/21616561 IEDB:RV An allergic contact dermatitis that has_allergic_trigger 4-tert-butylphenol. allergic contact dermatitis to PTBP allergic contact dermatitis to butylphen disease_ontology DOID:0040068 4-tert-butylphenol allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger 4-tert-butylphenol. url:https://www.ncbi.nlm.nih.gov/pubmed/8462290 IEDB:RV An allergic contact dermatitis that has_allergic_trigger 1-chloro-2,4-dinitrobenzene. allergic contact dermatitis to DNCB allergic contact dermatitis to dinitrochlorobenzene disease_ontology DOID:0040069 1-chloro-2,4-dinitrobenzene allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger 1-chloro-2,4-dinitrobenzene. url:https://www.ncbi.nlm.nih.gov/pubmed/17008874 IEDB:RV A drug allergy that has_allergic_trigger co-trimoxazole. SNOMEDCT_US_2023_03_01:294594004 UMLS_CUI:C0571504 Bactrim allergy TMP/SMX allergy cotrimoxazol allergy trimethoprim/sulfamethoxazole allergy disease_ontology DOID:0040070 co-trimoxazole allergy A drug allergy that has_allergic_trigger co-trimoxazole. url:https://www.ncbi.nlm.nih.gov/pubmed/445303 IEDB:RV A drug allergy that has_allergic_trigger sodium aurothiomalate. SNOMEDCT_US_2023_03_01:294239008 UMLS_CUI:C0571155 gold sodium thiomalate allergy disease_ontology DOID:0040071 sodium aurothiomalate allergy A drug allergy that has_allergic_trigger sodium aurothiomalate. url:https://www.ncbi.nlm.nih.gov/pubmed/445303 IEDB:RV An allergic contact dermatitis that has_allergic_trigger parthenolide. allergic contact dermatitis to feverfew disease_ontology DOID:0040072 parthenolide allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger parthenolide. url:https://www.ncbi.nlm.nih.gov/pubmed/17986299 IEDB:RV A drug allergy that has_allergic_trigger disodium cromoglycate. DSCG allergy disease_ontology DOID:0040073 disodium cromoglycate allergy A drug allergy that has_allergic_trigger disodium cromoglycate. url:https://www.ncbi.nlm.nih.gov/pubmed/3128591 IEDB:RV An allergic contact dermatitis that has_allergic_trigger formaldehyde. SNOMEDCT_US_2023_03_01:294426006 UMLS_CUI:C0571339 allergic contact dermatitis to formalin disease_ontology DOID:0040074 formaldehyde allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger formaldehyde. url:https://www.ncbi.nlm.nih.gov/pubmed/7902023 IEDB:RV An allergic contact dermatitis that has_allergic_trigger benzo[d]isothiazol-3-one. allergic contact dermatitis to BIT allergic contact dermatitis to benzisothiazolone disease_ontology DOID:0040075 benzo[d]isothiazol-3-one allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger benzo[d]isothiazol-3-one. url:https://www.ncbi.nlm.nih.gov/pubmed/6446435 IEDB:RV A drug allergy that has_allergic_trigger phthalyl group. SNOMEDCT_US_2023_03_01:294571000 UMLS_CUI:C0571482 phthalyl allergy disease_ontology DOID:0040076 phthalyl group allergy A drug allergy that has_allergic_trigger phthalyl group. url:https://www.ncbi.nlm.nih.gov/pubmed/7400667 IEDB:RV A drug allergy that has_allergic_trigger alcuronium bromide. disease_ontology DOID:0040077 alcuronium bromide allergy A drug allergy that has_allergic_trigger alcuronium bromide. url:https://www.ncbi.nlm.nih.gov/pubmed/2215478 IEDB:RV A drug allergy that has_allergic_trigger gallamine. SNOMEDCT_US_2023_03_01:294229002 UMLS_CUI:C0571145 disease_ontology DOID:0040078 gallamine allergy A drug allergy that has_allergic_trigger gallamine. url:https://www.ncbi.nlm.nih.gov/pubmed/2215478 IEDB:RV An allergic contact dermatitis that has_allergic_trigger 2,4-dinitrophenyl group. allergic contact dermatitis to DNP disease_ontology DOID:0040079 2,4-dinitrophenyl allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger 2,4-dinitrophenyl group. url:https://www.ncbi.nlm.nih.gov/pubmed/17008874 IEDB:RV A drug allergy that has_allergic_trigger patent blue V. disease_ontology DOID:0040080 patent blue V allergy A drug allergy that has_allergic_trigger patent blue V. url:https://www.ncbi.nlm.nih.gov/pubmed/19804438 IEDB:RV A respiratory allergy that has_allergic_trigger acid anhydride. disease_ontology DOID:0040081 acid anhydride respiratory allergy A respiratory allergy that has_allergic_trigger acid anhydride. url:https://www.ncbi.nlm.nih.gov/pubmed/6643876 IEDB:RV A drug allergy that has_allergic_trigger oxirane. ETO allergy ethylene oxide allergy disease_ontology DOID:0040082 oxirane allergy A drug allergy that has_allergic_trigger oxirane. url:https://www.ncbi.nlm.nih.gov/pubmed/3932500 IEDB:RV A bacterial pneumonia has_material_basis_in Chlamydia pneumoniae. ICD10CM:J16.0 ICD9CM:483.1 disease_ontology DOID:0040083 Chlamydia pneumonia A bacterial pneumonia has_material_basis_in Chlamydia pneumoniae. url:https://www.ncbi.nlm.nih.gov/pubmed/16831205 IEDB:RV A bacterial pneumonia has_material_basis_in Streptococcus pneumoniae. ICD10CM:J13 ICD9CM:481 disease_ontology DOID:0040084 Streptococcus pneumonia A bacterial pneumonia has_material_basis_in Streptococcus pneumoniae. url:https://www.ncbi.nlm.nih.gov/pubmed/26396191 IEDB:RV A bacterial infectious disease has_material_basis_in Bacteria. ICD9CM:995.91 SNOMEDCT_US_2021_09_01:10001005 disease_ontology DOID:0040085 bacterial sepsis A bacterial infectious disease has_material_basis_in Bacteria. url:https://www.ncbi.nlm.nih.gov/pubmed/20421654 IEDB:RV A viral infectious disease has_material_basis_in BK polyomavirus. SNOMEDCT_US_2023_03_01:713886006 UMLS_CUI:C1697878 PVAN polyomavirus associated nephropathy disease_ontology DOID:0040086 Polyomavirus-associated nephropathy A viral infectious disease has_material_basis_in BK polyomavirus. url:https://www.ncbi.nlm.nih.gov/pubmed/16537617 IEDB:RV PVAN An autoimmune disease of peripheral nervous system that results in peripheral neuropathy. disease_ontology DOID:0040087 autoimmune peripheral neuropathy An autoimmune disease of peripheral nervous system that results in peripheral neuropathy. url:https://www.ncbi.nlm.nih.gov/pubmed/7693874 IEDB:RV An autoimmune disease of eyes, ear, nose and throat that is located_in the uvea. disease_ontology DOID:0040088 autoimmune uveitis An autoimmune disease of eyes, ear, nose and throat that is located_in the uvea. url:https://www.ncbi.nlm.nih.gov/pubmed/12938234 IEDB:RV An autoimmune disease of peripheral nervous system that is located_in the neuron projection bundle connecting eye with brain. disease_ontology DOID:0040089 autoimmune optic neuritis An autoimmune disease of peripheral nervous system that is located_in the neuron projection bundle connecting eye with brain. url:https://www.ncbi.nlm.nih.gov/pubmed/7516573 IEDB:RV An autoimmune disease of gastrointestinal tract that is located_in the stomach. disease_ontology DOID:0040090 autoimmune gastritis An autoimmune disease of gastrointestinal tract that is located_in the stomach. url:https://www.ncbi.nlm.nih.gov/pubmed/12645953 IEDB:RV An autoimmune disease of endocrine system that is located_in the pancreas. MESH:D000081012 SNOMEDCT_US_2023_03_01:448542008 UMLS_CUI:C2609129 disease_ontology DOID:0040091 autoimmune pancreatitis MESH:D000081012 An autoimmune disease of endocrine system that is located_in the pancreas. url:https://www.ncbi.nlm.nih.gov/pubmed/19940298 IEDB:RV An ankylosing spondylitis with onset during childhood. ICD10CM:M08.1 SNOMEDCT_US_2023_03_01:201802002 UMLS_CUI:C0409675 disease_ontology DOID:0040092 juvenile ankylosing spondylitis An ankylosing spondylitis with onset during childhood. url:https://www.ncbi.nlm.nih.gov/pubmed/7541736 IEDB:RV A lupus erythematosus caused by chronic use of certain drugs. ICD10CM:M32.0 NCI:C114354 ORDO:231111 SNOMEDCT_US_2023_03_01:80258006 UMLS_CUI:C0263591 DIL DILE disease_ontology DOID:0040093 drug-induced lupus erythematosus A lupus erythematosus caused by chronic use of certain drugs. url:https://www.ncbi.nlm.nih.gov/pubmed/1378852 IEDB:RV DIL DILE An autoimmune disease of urogenital tract that is located_in the renal glomerulus. DOID:0050146 disease_ontology DOID:0040094 autoimmune glomerulonephritis An autoimmune disease of urogenital tract that is located_in the renal glomerulus. url:https://www.ncbi.nlm.nih.gov/pubmed/8809141 IEDB:RV An autoimmune disease of cardiovascular system that is characterized by deterioration of the function of the heart muscle. disease_ontology DOID:0040095 autoimmune cardiomyopathy An autoimmune disease of cardiovascular system that is characterized by deterioration of the function of the heart muscle. url:https://www.ncbi.nlm.nih.gov/pubmed/10762456 IEDB:RV An autoimmune disease of cardiovascular system that is characterized by a build up of plaque in the arteries. disease_ontology DOID:0040096 autoimmune atherosclerosis An autoimmune disease of cardiovascular system that is characterized by a build up of plaque in the arteries. url:https://www.ncbi.nlm.nih.gov/pubmed/17097662 IEDB:RV An autoimmune disease of cardiovascular system that is characterized by inflammation of the blood vessels. SNOMEDCT_US_2023_03_01:427213005 UMLS_CUI:C1328843 disease_ontology DOID:0040097 autoimmune vasculitis An autoimmune disease of cardiovascular system that is characterized by inflammation of the blood vessels. url:https://www.ncbi.nlm.nih.gov/pubmed/23549081 IEDB:RV A pemphigus that is characterized by blistered skin as a result of self-reactive T and B cells that target BP180. ICD10CM:O26.4 disease_ontology DOID:0040098 pemphigus gestationis A pemphigus that is characterized by blistered skin as a result of self-reactive T and B cells that target BP180. url:https://www.ncbi.nlm.nih.gov/pubmed/16552711 IEDB:RV A vasculitis with purpuric ulcers. ICD10CM:L95.0 ICD9CM:709.1 livedoid vasculopathy disease_ontology DOID:0040099 livedoid vasculitis A vasculitis with purpuric ulcers. url:https://www.ncbi.nlm.nih.gov/pubmed/10925314 IEDB:RV An autoimmune disease of endocrine system characterized by hypoglycemia caused by antibodies to insulin. SNOMEDCT_US_2023_03_01:408539000 UMLS_CUI:C0854359 insulin autoimmune syndrome disease_ontology DOID:0040100 Hirata disease An autoimmune disease of endocrine system characterized by hypoglycemia caused by antibodies to insulin. url:https://www.ncbi.nlm.nih.gov/pubmed/10445096 IEDB:RV An allergic contact dermatitis that has_allergic_trigger N,N-diphenylthiourea. disease_ontology neoprene allergy DOID:0040101 N,N'-diphenylthiourea allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger N,N-diphenylthiourea. url:https://www.ncbi.nlm.nih.gov/pubmed/28295200 IEDB:RV An allergic contact dermatitis that has_allergic_trigger N,N-diethylthiourea. disease_ontology neoprene allergy DOID:0040102 N,N'-diethylthiourea allergic contact dermatitis An allergic contact dermatitis that has_allergic_trigger N,N-diethylthiourea. url:https://www.ncbi.nlm.nih.gov/pubmed/28295200 IEDB:RV A cephalosporin allergy that has_allergic_trigger cefotiam. disease_ontology DOID:0040103 cefotiam allergy A cephalosporin allergy that has_allergic_trigger cefotiam. url:https://www.ncbi.nlm.nih.gov/pubmed/28543395 IEDB:RV A toluene meta-diisocyanate allergic asthma that has_allergic_trigger toluene 2,4-diisocyanate. disease_ontology DOID:0040104 toluene 2,4-diisocyanate allergic asthma A toluene meta-diisocyanate allergic asthma that has_allergic_trigger toluene 2,4-diisocyanate. url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194110/ IEDB:RV disease_ontology DOID:0050001 obsolete Actinomadura madurae infectious disease true disease_ontology DOID:0050002 obsolete Actinomadura pelletieri infectious disease true disease_ontology DOID:0050003 obsolete Streptomyces somaliensis infectious disease true A gonococcal seminal vesiculitis that is characterized by back pain, perineal pain, pain with ejaculation, hematospermia and voiding symptoms resulting from inflammation located_in the seminal vesicles caused by Neisseria gonorrhoeae infection. SNOMEDCT_US_2023_03_01:301990003 UMLS_CUI:C0578661 disease_ontology DOID:0050004 seminal vesicle acute gonorrhea A gonococcal seminal vesiculitis that is characterized by back pain, perineal pain, pain with ejaculation, hematospermia and voiding symptoms resulting from inflammation located_in the seminal vesicles caused by Neisseria gonorrhoeae infection. url:https://en.wikipedia.org/wiki/Seminal_vesicle#Inflammation A strongyloidiasis that involves parasitic infection by the filariform larvae of Strongyloides stercoralis, which penetrate the human skin causing urticarial rashes in the buttocks and waist areas. disease_ontology DOID:0050007 obsolete cutaneous strongyloidiasis true A strongyloidiasis that involves infection of intestine with Strongyloides stercoralis, which results in abdominal pain, diarrhea, ileus, massive gastrointestinal bleeding, severe malabsorption, and peritonitis. disease_ontology DOID:0050009 obsolete intestinal strongyloidiasis true A strongyloidiasis that involves infection of intestine with Strongyloides stercoralis, which results in abdominal pain, diarrhea, ileus, massive gastrointestinal bleeding, severe malabsorption, and peritonitis. url:http://www.dpd.cdc.gov/DPDx/HTML/Strongyloidiasis.htm url:http://www.merck.com/mmpe/sec14/ch182/ch182i.html?qt=strongyloidiasis&alt=sh A mansonelliasis that involves parasitic infection by the nematode Mansonella perstans, which resides in body cavities and the surrounding tissues causing angioedema, pruritus, fever, headaches, arthralgias, and neurologic manifestations. Midges transmit the disease. disease_ontology DOID:0050010 obsolete Mansonella perstans infectious disease true A mansonelliasis that involves parasitic infection by the nematode Mansonella perstans, which resides in body cavities and the surrounding tissues causing angioedema, pruritus, fever, headaches, arthralgias, and neurologic manifestations. Midges transmit the disease. url:http://www.dpd.cdc.gov/dpdx/HTML/Filariasis.htm A mansonelliasis that involves parasitic infection by the nematode Mansonella streptocerca, which resides in the dermis and subcutaneous tissue causing pruritus, papular eruptions and pigmentation changes. Midges transmit the disease. disease_ontology DOID:0050011 obsolete Mansonella streptocerca infectious disease true A mansonelliasis that involves parasitic infection by the nematode Mansonella streptocerca, which resides in the dermis and subcutaneous tissue causing pruritus, papular eruptions and pigmentation changes. Midges transmit the disease. url:http://www.dpd.cdc.gov/dpdx/HTML/Filariasis.htm A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus, which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash. GARD:6038 Chikungunya fever disease_ontology DOID:0050012 chikungunya A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus, which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash. url:http://en.wikipedia.org/wiki/Chikungunya_virus An acquired metabolic disease that is characterized by abnormal carbohydrate metabolism. disease_ontology DOID:0050013 obsolete carbohydrate metabolism disease true An acquired metabolic disease that is characterized by abnormal carbohydrate metabolism. url:http://www.nlm.nih.gov/medlineplus/metabolicdisorders.html A viral infectious disease that results_in infection in deer, has_material_basis_in Epizootic hemorrhagic disease virus, which is transmitted_by Culicoides biting midges. The infection has_symptom hemorrhages in many tissues including the skin, heart, and gastrointestinal tract, and has_symptom ulcers of the tongue, dental pad, palate, rumen, and omasum. disease_ontology EHD DOID:0050014 obsolete epizootic hemorrhagic disease true A viral infectious disease that results_in infection in deer, has_material_basis_in Epizootic hemorrhagic disease virus, which is transmitted_by Culicoides biting midges. The infection has_symptom hemorrhages in many tissues including the skin, heart, and gastrointestinal tract, and has_symptom ulcers of the tongue, dental pad, palate, rumen, and omasum. url:http://www.cfsph.iastate.edu/Factsheets/pdfs/epizootic_hemorrhagic_disease.pdf A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Rocio virus, which is transmitted_by Psorophora ferox and transmitted_by Aedes species of mosquitoes. The infection has_symptom abdominal distension, has_symptom confusion, has_symptom motor impairment, has_symptom difficulty in walking and maintaining balance, has_symptom meningeal irritation, and has_symptom cerebellar syndrome. disease_ontology DOID:0050015 obsolete Rocio virus encephalitis true A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Rocio virus, which is transmitted_by Psorophora ferox and transmitted_by Aedes species of mosquitoes. The infection has_symptom abdominal distension, has_symptom confusion, has_symptom motor impairment, has_symptom difficulty in walking and maintaining balance, has_symptom meningeal irritation, and has_symptom cerebellar syndrome. url:http://books.google.com/books?id=5O0somr0w18C&pg=RA1-PA1198&lpg=RA1-PA1198&dq#v=onepage&q=&f=false url:http://www.ncbi.nlm.nih.gov/sites/entrez/17622628 url:http://www.scielo.br/pdf/rsp/v20n3/01.pdf disease_ontology DOID:0050024 obsolete Ehrlichia ewingii ehrlichiosis true An ehrlichiosis that results in infection located in granular leukocyte, has_material_basis_in Anaplasma phagocytophilum, which is transmitted by lone star tick (Amblyomma americanum). The infection has symptom headache, has symptom muscle aches, has symptom fatigue, has symptom fever and has symptom rash. DOID:0050021 DOID:0050022 human granulocytic ehrlichiosis disease_ontology HGE DOID:0050025 human granulocytic anaplasmosis An ehrlichiosis that results in infection located in granular leukocyte, has_material_basis_in Anaplasma phagocytophilum, which is transmitted by lone star tick (Amblyomma americanum). The infection has symptom headache, has symptom muscle aches, has symptom fatigue, has symptom fever and has symptom rash. url:https://www.ncbi.nlm.nih.gov/pubmed/25999228 HGE An ehrlichiosis that results in infection located in monocyte or located in macrophage, has_material_basis_in Ehrlichia chaffeensis, which is transmitted by black-legged tick (Ixodes scapularis), transmitted by western black-legged tick (Ixodes pacificus) or transmitted by castor bean tick (Ixodes ricinus). The infection has symptom headache, has symptom muscle aches, has symptom fatigue, has symptom fever and has symptom rash. DOID:14091 GARD:72 disease_ontology Ehrlichiosis chafeensis DOID:0050026 human monocytic ehrlichiosis An ehrlichiosis that results in infection located in monocyte or located in macrophage, has_material_basis_in Ehrlichia chaffeensis, which is transmitted by black-legged tick (Ixodes scapularis), transmitted by western black-legged tick (Ixodes pacificus) or transmitted by castor bean tick (Ixodes ricinus). The infection has symptom headache, has symptom muscle aches, has symptom fatigue, has symptom fever and has symptom rash. url:https://rarediseases.org/rare-diseases/human-monocytic-ehrlichiosis-hme/ An acquired metabolic disease that is characterized by abnormal mineral metabolism. disease_ontology DOID:0050032 mineral metabolism disease An acquired metabolic disease that is characterized by abnormal mineral metabolism. url:http://www.nlm.nih.gov/medlineplus/metabolicdisorders.html A spotted fever that has_material_basis_in Rickettsia africae, which is transmitted_by ticks (Amblyomma hebraeum and Amblyomma variegatum). The infection has_symptom fever, has_symptom eschar and has_symptom maculopapular rash. DOID:0050034 DOID:0050036 Rickettsia africae spotted fever south african tick-bite fever disease_ontology DOID:0050035 African tick-bite fever A spotted fever that has_material_basis_in Rickettsia africae, which is transmitted_by ticks (Amblyomma hebraeum and Amblyomma variegatum). The infection has_symptom fever, has_symptom eschar and has_symptom maculopapular rash. url:http://jcm.asm.org/cgi/reprint/42/2/816 url:http://www.cdc.gov/otherspottedfever/index.html A spotted fever that has_material_basis_in Rickettsia conorii subsp caspia, which is transmitted_by ticks (Rhipicephalus pumilio and Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities. disease_ontology DOID:0050041 Astrakhan spotted fever A spotted fever that has_material_basis_in Rickettsia conorii subsp caspia, which is transmitted_by ticks (Rhipicephalus pumilio and Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities. url:http://www.cdc.gov/otherspottedfever/index.html url:https://pubmed.ncbi.nlm.nih.gov/7985764/ A spotted fever that has_material_basis_in Rickettsia conorii subsp indica, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities. disease_ontology DOID:0050042 Indian tick typhus A spotted fever that has_material_basis_in Rickettsia conorii subsp indica, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities. url:http://www.biomedcentral.com/1471-2180/5/11 url:http://www.cdc.gov/otherspottedfever/index.html A spotted fever that has_material_basis_in Rickettsia conorii subsp israelensis, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities. disease_ontology Israeli spotted fever DOID:0050043 Israeli tick typhus A spotted fever that has_material_basis_in Rickettsia conorii subsp israelensis, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities. url:http://www.biomedcentral.com/1471-2180/5/11 url:http://www.cdc.gov/otherspottedfever/index.html A spotted fever that has_material_basis_in Rickettsia heilongjiangensis, which is transmitted_by ticks (Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom maculopapular rash, and has_symptom regional adenopathy. Rickettsia heilongjiangensis spotted fever disease_ontology DOID:0050046 Far Eastern spotted fever A spotted fever that has_material_basis_in Rickettsia heilongjiangensis, which is transmitted_by ticks (Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom maculopapular rash, and has_symptom regional adenopathy. url:http://www.cdc.gov/eid/content/16/8/pdfs/1306.pdf url:http://www.cdc.gov/otherspottedfever/index.html A spotted fever that has_material_basis_in Rickettsia honei, which is transmitted_by cayenne ticks (Amblyomma cajennense). The infection has_symptom mild spotted fever, has_symptom eschar and has_symptom adenopathy. DOID:0050048 Thai tick typhus disease_ontology FISF DOID:0050047 Flinders Island spotted fever A spotted fever that has_material_basis_in Rickettsia honei, which is transmitted_by cayenne ticks (Amblyomma cajennense). The infection has_symptom mild spotted fever, has_symptom eschar and has_symptom adenopathy. url:https://www.cdc.gov/otherspottedfever/imported/index.html FISF A spotted fever that has_material_basis_in Rickettsia japonica, which is transmitted_by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has_symptom fever, has_symptom eschars, has_symptom regional adenopathy, and has_symptom rash on extremities. DOID:0050049 Rickettsia japonica spotted fever oriental spotted fever disease_ontology DOID:0050050 Japanese spotted fever A spotted fever that has_material_basis_in Rickettsia japonica, which is transmitted_by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has_symptom fever, has_symptom eschars, has_symptom regional adenopathy, and has_symptom rash on extremities. url:http://www.cdc.gov/otherspottedfever/index.html url:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627607/pdf/9204291.pdf A spotted fever that has_material_basis_in Rickettsia parkeri, which is transmitted_by Gulf Coast tick (Amblyomma maculatum). The infection has_symptom fever, has_symptom headache, has_symptom eschar, and has_symptom rash. maculatum infection disease_ontology DOID:0050051 Rickettsia parkeri spotted fever A spotted fever that has_material_basis_in Rickettsia parkeri, which is transmitted_by Gulf Coast tick (Amblyomma maculatum). The infection has_symptom fever, has_symptom headache, has_symptom eschar, and has_symptom rash. url:http://cmr.asm.org/cgi/content/full/18/4/719#Rickettsia_parkeri url:http://www.cdc.gov/otherspottedfever/index.html A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, and has_symptom maculopapular rash progressing into papular or petechial rash. DOID:0050056 DOID:1708 GARD:7585 MESH:D012373 Tick typhus disease_ontology Brazilian spotted Choix Exanthematic typhus of Sao Paulo Fiebre maculosa Fiebre manchada Sao Paulo typhus So Paulo fever Tobia fever DOID:0050052 Rocky Mountain spotted fever A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, and has_symptom maculopapular rash progressing into papular or petechial rash. url:http://cmr.asm.org/cgi/content/full/18/4/719#Rickettsia_rickettsii_%28Rocky_Mountain_spotted_fever%29 url:http://www.cdc.gov/otherspottedfever/index.html disease_ontology DOID:0050053 obsolete Rickettsia honei spotted fever true A gastrointestinal anthrax that results in infection located in mucosa of oropharynx, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite. disease_ontology DOID:0050059 oropharyngeal anthrax A gastrointestinal anthrax that results in infection located in mucosa of oropharynx, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite. url:https://www.ncbi.nlm.nih.gov/pubmed/3934300 A primary bacterial infectious disease that results_in infection located_in skin, has_material_basis_in Erysipelothrix rhusiopathiae, which is transmitted_by contact with infected animals. The infection has_symptom redness of skin, has_symptom tenderness of skin and has_symptom warmth of skin. MESH:D004887 disease_ontology DOID:0050061 erysipeloid A primary bacterial infectious disease that results_in infection located_in skin, has_material_basis_in Erysipelothrix rhusiopathiae, which is transmitted_by contact with infected animals. The infection has_symptom redness of skin, has_symptom tenderness of skin and has_symptom warmth of skin. url:https://en.wikipedia.org/wiki/Erysipeloid disease_ontology DOID:0050063 obsolete abortive plague true disease_ontology DOID:0050065 obsolete cutaneous listeriosis true disease_ontology DOID:0050066 obsolete Listeria meningoencephalitis true disease_ontology DOID:0050067 obsolete Listeria septicaemia true A bubonic plague that results_in a benign form of bubonic plague, has_symptom fever, has_symptom lymphadenitis, has_symptom headache and has_symptom prostration. disease_ontology DOID:0050068 obsolete pestis minor true disease_ontology DOID:0050069 obsolete Yersinia pestis infectious disease true disease_ontology DOID:0050070 obsolete plague meningitis true A primary systemic mycosis that is a fungal infection located_in lungs, or located_in skin, which results_in disseminated granulomatous pulmonary process and cutaneous infection in rodents, small wild mammals and humans, has_material_basis_in Chrysosporium parvum or Emmonsia crescens. MESH:C000656784 disease_ontology DOID:0050072 adiaspiromycosis A primary systemic mycosis that is a fungal infection located_in lungs, or located_in skin, which results_in disseminated granulomatous pulmonary process and cutaneous infection in rodents, small wild mammals and humans, has_material_basis_in Chrysosporium parvum or Emmonsia crescens. url:http://www.eblue.org/article/S0190-9622%2804%2901331-3/abstract An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage. disease_ontology DOID:0050073 invasive aspergillosis An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage. url:http://www.merck.com/mmhe/sec17/ch197/ch197b.html?qt=invasive%20pulmonary%20aspergillosis&alt=sh url:http://www.nlm.nih.gov/medlineplus/ency/article/001326.htm An aspergillosis that involves fungal infection of the tonsils by Aspergillus species. disease_ontology DOID:0050074 obsolete tonsillar aspergillosis true An aspergillosis that involves fungal infection of the tonsils by Aspergillus species. url:https://www.ncbi.nlm.nih.gov/pubmed/792373 A primary systemic mycosis that results_in fungal infection located_in lungs, has_material_basis_in Blastomyces dermatitidis, transmitted_by airborne spores and has_symptom lung lesions, has_symptom pleural thickening and results_in_formation_of pulmonary nodules. DOID:0050076 DOID:0050077 disease_ontology DOID:0050075 obsolete pulmonary blastomycosis true disease_ontology DOID:0050078 obsolete cervix tuberculosis true disease_ontology DOID:0050079 obsolete niacin deficiency true disease_ontology DOID:0050080 obsolete iodine deficiency true A viral infectious disease that results_in infection located_in liver, has_material_basis_in Torque teno virus, which is transmitted_by blood transfusion. DOID:0050081 TT virus liver infection Transfussion-transmitted virus liver infection disease_ontology human circovirus infectious disease DOID:0050082 obsolete hepatic Torque teno virus infectious disease true A nutritional deficiency that is disease characterized by a cardiomyopathy secondary to selenium deficiency. GARD:8761 MESH:C536166 disease_ontology DOID:0050083 Keshan disease A nutritional deficiency that is disease characterized by a cardiomyopathy secondary to selenium deficiency. url:https://en.wikipedia.org/wiki/Keshan_disease An upper respiratory tract disease involving inflammation of the nasal cavities and trachea caused by feline herpesvirus 1, of the family Herpesviridae in cats and especially young kittens that is characterized by sneezing, conjunctivitis with discharge, and nasal discharges. Feline viral rhinotracheitis feline coryza feline influenza disease_ontology DOID:0050084 Not a human disease. obsolete rhinotracheitis true An upper respiratory tract disease involving inflammation of the nasal cavities and trachea caused by feline herpesvirus 1, of the family Herpesviridae in cats and especially young kittens that is characterized by sneezing, conjunctivitis with discharge, and nasal discharges. url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=rhinotracheitis A subcutaneous mycosis that involves fungal infection of the subcutaneous tissue caused by members of the order Entomophthorales. disease_ontology DOID:0050085 obsolete entomophthoromycosis true A subcutaneous mycosis that involves fungal infection of the subcutaneous tissue caused by members of the order Entomophthorales. url:http://www.doctorfungus.org/mycoses/human/zygo/zygomycosis.htm An opportunistic mycosis that results_in fungal infection located_in cutaneous tissues or located_in subcutaneous tissues followed by a traumatic implantation of fungal elements through the skin, has_material_basis_in Mucorales molds and has_symptom necrotic lesions which progressively evolve from the epidermis into dermis and even muscle. disease_ontology DOID:0050086 obsolete cutaneous mucormycosis true An opportunistic mycosis that results_in fungal infection located_in cutaneous tissues or located_in subcutaneous tissues followed by a traumatic implantation of fungal elements through the skin, has_material_basis_in Mucorales molds and has_symptom necrotic lesions which progressively evolve from the epidermis into dermis and even muscle. url:http://mycology.adelaide.edu.au/Mycoses/Subcutaneous/Zygomycosis/ url:http://www.doctorfungus.org/mycoses/human/zygo/zygomycosis.htm url:http://www.springerlink.com/content/c7286n02m8327567/fulltext.pdf A opportunistic mycosis that results_in fungal infection located_in gastrointestinal tract, has_material_basis_in Mucorales molds in immunocompromised patients, results_in_formation_of intra-abdominal abscess and has_symptom abdominal pain, has_symptom distention, has_symptom nausea, and has_symptom vomiting. disease_ontology DOID:0050088 obsolete gastrointestinal mucormycosis true A opportunistic mycosis that results_in fungal infection located_in gastrointestinal tract, has_material_basis_in Mucorales molds in immunocompromised patients, results_in_formation_of intra-abdominal abscess and has_symptom abdominal pain, has_symptom distention, has_symptom nausea, and has_symptom vomiting. url:https://www.ncbi.nlm.nih.gov/pubmed/16020690 An opportunistic mycosis that results_in fungal infection located_in lungs, has_material_basis_in Mucorales molds and has_symptom hemoptysis and has_symptom necrosis. disease_ontology DOID:0050089 obsolete pulmonary mucormycosis true An opportunistic mycosis that results_in fungal infection located_in lungs, has_material_basis_in Mucorales molds and has_symptom hemoptysis and has_symptom necrosis. url:http://archinte.ama-assn.org/cgi/reprint/159/12/1301.pdf url:http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4 An opportunistic mycosis that results_in fungal infection located_in nose, located_in sinuses, located_in eyes, and located_in brain of immunocompromised individuals and has_symptom orbital cellulitis, has_symptom proptosis, has_symptom pus discharge from the nose, and has_symptom seizures. disease_ontology DOID:0050090 obsolete rhinocerebral mucormycosis true An opportunistic mycosis that results_in fungal infection located_in nose, located_in sinuses, located_in eyes, and located_in brain of immunocompromised individuals and has_symptom orbital cellulitis, has_symptom proptosis, has_symptom pus discharge from the nose, and has_symptom seizures. url:http://www.merck.com/mmhe/sec17/ch197/ch197h.html A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Paracoccidioides brasiliensis. disease_ontology DOID:0050091 obsolete disseminated paracoccidioidomycosis true A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Paracoccidioides brasiliensis. url:http://www.mycology.adelaide.edu.au/Mycoses/Dimorphic_systemic/Paracoccidioidomycosis/ A primary systemic mycosis that results_in inflammation located_in lungs, has_material_basis_in Paracoccidioides brasiliensis and has_symptom cough, has_symptom fever, has_symptom night sweats, has_symptom malaise, and has_symptom weight loss. disease_ontology DOID:0050092 obsolete pulmonary paracoccidioidomycosis true A primary systemic mycosis that results_in inflammation located_in lungs, has_material_basis_in Paracoccidioides brasiliensis and has_symptom cough, has_symptom fever, has_symptom night sweats, has_symptom malaise, and has_symptom weight loss. url:http://www.mycology.adelaide.edu.au/Mycoses/Dimorphic_systemic/Paracoccidioidomycosis/ A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Sporothrix schenckii, a dimorphic fungus. disease_ontology DOID:0050093 obsolete disseminated sporotrichosis true A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Sporothrix schenckii, a dimorphic fungus. url:http://en.wikipedia.org/wiki/Sporotrichosis A primary systemic mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, and located_in lymphatic vessel through direct inoculation from wood splinters or hay, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which results_in_formation_of erythematous papulonodular lesions at the site of implantation and along the lymphangitic channels which soon become palpable and ulcerate. disease_ontology DOID:0050094 obsolete lymphocutaneous sporotrichosis true A primary systemic mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, and located_in lymphatic vessel through direct inoculation from wood splinters or hay, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which results_in_formation_of erythematous papulonodular lesions at the site of implantation and along the lymphangitic channels which soon become palpable and ulcerate. url:http://emedicine.medscape.com/article/228723-overview url:http://www.mycology.adelaide.edu.au/Mycoses/Subcutaneous/Sporotrichosis/ A primary systemic mycosis that results_in fungal infection located_in lung, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which is transmitted_by airborne spores and has_symptom productive cough, has_symptom nodules and cavitations of the lungs, has_symptom fibrosis, and has_symptom swollen hilar lymph nodes. disease_ontology DOID:0050095 obsolete pulmonary sporotrichosis true A primary systemic mycosis that results_in fungal infection located_in lung, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which is transmitted_by airborne spores and has_symptom productive cough, has_symptom nodules and cavitations of the lungs, has_symptom fibrosis, and has_symptom swollen hilar lymph nodes. url:http://en.wikipedia.org/wiki/Sporotrichosis A dermatophytosis that results_in fungal infection which effects horny layer of epidermis of the bearded areas located_in face or located_in neck, has_material_basis_in Trichophyton mentagrophytes or has_material_basis_in Trichophyton verrucosum, which also effects hair, and effects nail and has_symptom inflammatory kerion-like plaques, and results_in_formation_of noninflammatory superficial perifollicular pustules. MESH:C000656825 dermatophytosis of beard disease_ontology DOID:0050096 tinea barbae A dermatophytosis that results_in fungal infection which effects horny layer of epidermis of the bearded areas located_in face or located_in neck, has_material_basis_in Trichophyton mentagrophytes or has_material_basis_in Trichophyton verrucosum, which also effects hair, and effects nail and has_symptom inflammatory kerion-like plaques, and results_in_formation_of noninflammatory superficial perifollicular pustules. url:https://www.merckmanuals.com/professional/dermatologic-disorders/fungal-skin-infections/tinea-barbae A tinea capitis that results_in fungal infection located_in cuticle of hair, has_material_basis_in Microsporum canis, has_material_basis_in Microsporum gypseum, has_material_basis_in Trichophyton equinum, and has_material_basis_in Trichophyton verrucosum, which produce arthroconidia on the exterior of the hair shaft. disease_ontology DOID:0050097 ectothrix infectious disease A tinea capitis that results_in fungal infection located_in cuticle of hair, has_material_basis_in Microsporum canis, has_material_basis_in Microsporum gypseum, has_material_basis_in Trichophyton equinum, and has_material_basis_in Trichophyton verrucosum, which produce arthroconidia on the exterior of the hair shaft. url:https://www.merckmanuals.com/professional/dermatologic-disorders/fungal-skin-infections/tinea-capitis An ectothrix infectious disease that results_in non-inflammatory fungal infection located_in scalp and located_in skin, has_material_basis_in Microsporum audouinii. disease_ontology DOID:0050098 obsolete Microsporum audouinii tinea capitis true An ectothrix infectious disease that results_in non-inflammatory fungal infection located_in scalp and located_in skin, has_material_basis_in Microsporum audouinii. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_audouinii.html An ectothrix infectious disease that results_in zoophilic fungal infection located_in hair, located_in skin, and located_in nail, has_material_basis_in Microsporum canis. disease_ontology DOID:0050099 obsolete Microsporum canis tinea capitis true An ectothrix infectious disease that results_in zoophilic fungal infection located_in hair, located_in skin, and located_in nail, has_material_basis_in Microsporum canis. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_canis.html An ectothrix infectious disease that results_in zoophilic fungal infection located_in skin, and located_in hair, has_material_basis_in Microsporum distortum, which causes infections in cats, dogs and other animals. disease_ontology DOID:0050100 obsolete Microsporum distortum tinea capitis true An ectothrix infectious disease that results_in zoophilic fungal infection located_in skin, and located_in hair, has_material_basis_in Microsporum distortum, which causes infections in cats, dogs and other animals. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_distortum.html An ectothrix infectious disease that results_in anthropophilic fungal infection located_in skin and located_in hair, has_material_basis_in Microsporum ferrugineum. disease_ontology DOID:0050101 obsolete Microsporum ferrugineum tinea capitis true An ectothrix infectious disease that results_in anthropophilic fungal infection located_in skin and located_in hair, has_material_basis_in Microsporum ferrugineum. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_ferrugineum.html An ectothrix infectious disease that results_in geophilic fungal infection located_in glabrous skin, located_in scalp and located_in hair, has_material_basis_in Microsporum gypseum, which results_in_formation_of inflammatory lesions. disease_ontology DOID:0050102 obsolete Microsporum gypseum tinea capitis true An ectothrix infectious disease that results_in geophilic fungal infection located_in glabrous skin, located_in scalp and located_in hair, has_material_basis_in Microsporum gypseum, which results_in_formation_of inflammatory lesions. url:http://archderm.highwire.org/cgi/reprint/64/3/309.pdf url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_gypseum.html url:http://www.springerlink.com/content/q856g32375864654/fulltext.pdf An ectothrix infectious disease that results_in geophilic and zoophilic fungal infection located_in skin, located_in scalp and located_in hair, has_material_basis_in Microsporum nanum, which results_in_formation_of chronic non-inflammatory lesions in pigs and humans. disease_ontology DOID:0050103 obsolete Microsporum nanum tinea capitis true An ectothrix infectious disease that results_in geophilic and zoophilic fungal infection located_in skin, located_in scalp and located_in hair, has_material_basis_in Microsporum nanum, which results_in_formation_of chronic non-inflammatory lesions in pigs and humans. url:http://www.jstor.org/stable/pdfplus/3756652.pdf url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_nanum.html An ectothrix infectious disease that results_in zoophilic inflammatory fungal infection located_in skin, located_in beard, located_in scalp and located_in nail in cattle and humans, has-agent Trichophyton verrucosum. disease_ontology DOID:0050104 obsolete Trichophyton verrucosum tinea capitis true An ectothrix infectious disease that results_in zoophilic inflammatory fungal infection located_in skin, located_in beard, located_in scalp and located_in nail in cattle and humans, has-agent Trichophyton verrucosum. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/verrucosum.html A tinea capitis that results_in fungal infection located_in hair, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes, which produce arthroconidia within the hair shaft only. disease_ontology DOID:0050105 endothrix infectious disease A tinea capitis that results_in fungal infection located_in hair, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes, which produce arthroconidia within the hair shaft only. url:http://www.mycology.adelaide.edu.au/Mycoses/Cutaneous/Dermatophytosis/ An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton soudanense. disease_ontology DOID:0050106 obsolete Trichophyton soudanense tinea capitis true An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton soudanense. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/soudanense.html An endothrix infectious disease that results_in anthropophilic fungal infection located_in skin, located_in nail and located_in scalp, has_material_basis_in Trichophyton tonsurans and results_in_formation_of scaling lesions. disease_ontology DOID:0050107 obsolete Trichophyton tonsurans tinea capitis true An endothrix infectious disease that results_in anthropophilic fungal infection located_in skin, located_in nail and located_in scalp, has_material_basis_in Trichophyton tonsurans and results_in_formation_of scaling lesions. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/tonsurans.html An endothrix infectious disease that results_in anthropophilic fungal infection located_in skin, located_in nail, located_in beard, and located_in scalp, has_material_basis_in Trichophyton violaceum and results_in_formation_of scaling lesions. The hairs become notably fragile and break easily at the level of the scalp. The rest of the infected follicle looks like black dots. disease_ontology DOID:0050108 obsolete Trichophyton violaceum tinea capitis true An endothrix infectious disease that results_in anthropophilic fungal infection located_in skin, located_in nail, located_in beard, and located_in scalp, has_material_basis_in Trichophyton violaceum and results_in_formation_of scaling lesions. The hairs become notably fragile and break easily at the level of the scalp. The rest of the infected follicle looks like black dots. url:http://www.doctorfungus.org/mycoses/human/other/Tinea_capitis_favosa.htm url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/violaceum.html A tinea favosa that results_in anthropophilic fungal infection located_in scalp, has_material_basis_in Trichophyton schoenleinii. It is a chronic, scarring form of tinea capitis, which results_in_formation_of scutula and has_symptom permanent hair loss. disease_ontology DOID:0050110 obsolete Trichophyton schoenleinii tinea capitis true A tinea favosa that results_in anthropophilic fungal infection located_in scalp, has_material_basis_in Trichophyton schoenleinii. It is a chronic, scarring form of tinea capitis, which results_in_formation_of scutula and has_symptom permanent hair loss. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/schoenlenii.html An ectothrix infectious disease that results_in geophilic fungal infection located_in scalp and located_in hair in humans and animals, has_material_basis_in Microsporum fulvum. disease_ontology DOID:0050111 obsolete Microsporum fulvum tinea capitis true An ectothrix infectious disease that results_in geophilic fungal infection located_in scalp and located_in hair in humans and animals, has_material_basis_in Microsporum fulvum. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Microsporum/Microsporum_fulvum.html An ectothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton megninii. disease_ontology DOID:0050112 obsolete Trichophyton megninii tinea capitis true An ectothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton megninii. url:http://emedicine.medscape.com/article/787217-overview url:http://www.provlab.ab.ca/mycol/tutorials/derm/tmegn.htm An ectothrix infectious disease that results_in zoophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton equinum. disease_ontology DOID:0050113 obsolete Trichophyton equinum tinea capitis true An ectothrix infectious disease that results_in zoophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton equinum. url:http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Dermatophytes/Trichophyton/equinum.html An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton yaoundei, results_in_formation_of lesions. disease_ontology DOID:0050115 obsolete Trichophyton yaoundei tinea capitis true An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton yaoundei, results_in_formation_of lesions. url:http://en.wikipedia.org/wiki/Trichophyton url:http://www.nature.com/jid/journal/v41/n1/pdf/jid19636a.pdf A tinea corporis that results_in fungal infection located_in skin, has_material_basis_in Trichophyton concentricum, which is characterized by ring-like growth in overlapping circles that may have an autosomal dominant genetic predisposition. disease_ontology DOID:0050116 tinea imbricata A tinea corporis that results_in fungal infection located_in skin, has_material_basis_in Trichophyton concentricum, which is characterized by ring-like growth in overlapping circles that may have an autosomal dominant genetic predisposition. url:https://www.sciencedirect.com/topics/medicine-and-dentistry/tinea-imbricata A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions. infectious disease DOID:10115 DOID:11078 DOID:1304 DOID:1321 DOID:2040 DOID:2288 DOID:3099 DOID:4120 DOID:4620 DOID:5256 DOID:945 DOID:95 DOID:9532 DOID:9696 ICD9CM:079.0 UMLS_CUI:C0001485 infectious disease disease_ontology DOID:0050117 DO:wk disease by infectious agent A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions. url:https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C26726 A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in La Crosse virus, which is transmitted_by treehole mosquito, Ochlerotatus triseriatus. The infection has_symptom seizures, has_symptom headache, has_symptom fever, has_symptom coma, and has_symptom paralysis. DOID:10840 ICD10CM:A83.5 ICD9CM:062.5 MESH:D004670 SNOMEDCT_US_2023_03_01:69627004 UMLS_CUI:C0014053 California Encephalitis California virus encephalitis Neuroinvasive California encephalitis virus infection disease_ontology DOID:0050118 La Crosse encephalitis A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in La Crosse virus, which is transmitted_by treehole mosquito, Ochlerotatus triseriatus. The infection has_symptom seizures, has_symptom headache, has_symptom fever, has_symptom coma, and has_symptom paralysis. url:http://www.cdc.gov/ncidod/dvbid/arbor/arbdet.htm A West Nile virus infectious disease that has_material_basis_in West Nile virus, which can cause meningitis, encephalitis, acute laccid paralysis, Parkingsonian-like conditions or movement disorder. WNND WNNS West nile neuroinvasive disease disease_ontology DOID:0050119 obsolete West Nile virus neurological syndrome true A West Nile virus infectious disease that has_material_basis_in West Nile virus, which can cause meningitis, encephalitis, acute laccid paralysis, Parkingsonian-like conditions or movement disorder. url:http://www.phac-aspc.gc.ca/wnv-vwn/hmncasedef-eng.php A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. DOID:6453 GARD:6589 ICD10CM:D76.1 MESH:D051359 MIM:PS267700 NCI:C34792 ORDO:540 SNOMEDCT_US_2023_03_01:190958003 UMLS_CUI:C0024291 haemophagocytic syndrome disease_ontology DOID:0050120 Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. hemophagocytic lymphohistiocytosis A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. url:http://ghr.nlm.nih.gov/condition/familial-hemophagocytic-lymphohistiocytosis url:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000500007&lng=pt&nrm=iso disease_ontology DOID:0050123 obsolete tuberculous encephalitis true A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth. DSS disease_ontology DOID:0050125 dengue shock syndrome A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth. url:http://en.wikipedia.org/wiki/Dengue_shock_syndrome DSS A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Tahyna virus, which is transmitted_by Aedes, transmitted_by Culex, and transmitted_by Ochlerotatus mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures. valtice fever disease_ontology Tahyna virus infection DOID:0050126 obsolete Tahyna virus encephalitis true A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Tahyna virus, which is transmitted_by Aedes, transmitted_by Culex, and transmitted_by Ochlerotatus mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures. url:http://www.cdc.gov/eid/content/15/2/306.htm url:http://www.springerlink.com/content/u67424r731431362/ A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. DOID:2052 DOID:9564 ICD10CM:J01 ICD9CM:461 NCI:C128411 SNOMEDCT_US_2023_03_01:195649005 UMLS_CUI:C0149512 disease_ontology DOID:0050127 sinusitis A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. url:http://en.wikipedia.org/wiki/sinusitis A diarrhea where there is an increase in the active secretion, or there is an inhibition of absorption causing little to no structural damage. The most common cause of this type of diarrhea is a cholera toxin that stimulates the secretion of anions, especially chloride ions. disease_ontology DOID:0050129 secretory diarrhea A diarrhea where there is an increase in the active secretion, or there is an inhibition of absorption causing little to no structural damage. The most common cause of this type of diarrhea is a cholera toxin that stimulates the secretion of anions, especially chloride ions. url:http://en.wikipedia.org/wiki/Diarrhea#Types_of_diarrhea A dirrhea that occurs when too much water is drawn into the bowels. This can be the result of maldigestion (e.g., pancreatic disease or Coeliac disease), in which the nutrients are left in the lumen to pull in water. Osmotic diarrhea can also be caused by osmotic laxatives (which work to alleviate constipation by drawing water into the bowels). In healthy individuals, too much magnesium or vitamin C or undigested lactose can produce osmotic diarrhea and distention of the bowel. A person who does not have lactose intolerance can have difficulty absorbing lactose after an extraordinarily high intake of dairy products. disease_ontology DOID:0050130 osmotic diarrhea A dirrhea that occurs when too much water is drawn into the bowels. This can be the result of maldigestion (e.g., pancreatic disease or Coeliac disease), in which the nutrients are left in the lumen to pull in water. Osmotic diarrhea can also be caused by osmotic laxatives (which work to alleviate constipation by drawing water into the bowels). In healthy individuals, too much magnesium or vitamin C or undigested lactose can produce osmotic diarrhea and distention of the bowel. A person who does not have lactose intolerance can have difficulty absorbing lactose after an extraordinarily high intake of dairy products. url:http://en.wikipedia.org/wiki/Diarrhea#Types_of_diarrhea A diarrhea which is caused by the rapid movement of food through the intestines (hypermotility). If the food moves too quickly through the GI tract, there is not enough time for sufficient nutrients and water to be absorbed. disease_ontology DOID:0050131 motility-related diarrhea A diarrhea which is caused by the rapid movement of food through the intestines (hypermotility). If the food moves too quickly through the GI tract, there is not enough time for sufficient nutrients and water to be absorbed. url:http://en.wikipedia.org/wiki/Diarrhea#Types_of_diarrhea A gastrointestinal system infectious disease involving diarrhea that occurs when there is damage to the mucosal lining or brush border, which leads to a passive loss of protein-rich fluids, and a decreased ability to absorb these lost fluids. It can be caused by bacterial infections, viral infections, parasitic infections, or autoimmune problems such as inflammatory bowel diseases. It can also be caused by tuberculosis, colon cancer, and enteritis. disease_ontology DOID:0050132 inflammatory diarrhea A gastrointestinal system infectious disease involving diarrhea that occurs when there is damage to the mucosal lining or brush border, which leads to a passive loss of protein-rich fluids, and a decreased ability to absorb these lost fluids. It can be caused by bacterial infections, viral infections, parasitic infections, or autoimmune problems such as inflammatory bowel diseases. It can also be caused by tuberculosis, colon cancer, and enteritis. url:http://en.wikipedia.org/wiki/Diarrhea#Types_of_diarrhea A fungal infectious disease that results_in infection of the outermost layer located_in skin or located_in hair shaft, has_material_basis_in Fungi. No living tissue is invaded and there is no cellular response from the host. DOID:13370 ICD10CM:B36.9 MESH:D010854 SNOMEDCT_US_2023_03_01:266218008 SNOMEDCT_US_2023_03_01:47382004 UMLS_CUI:C0031898 UMLS_CUI:C2980104 Steroid-modified tinea infection piedra disease_ontology DOID:0050133 Adding a UMLS CUI for piedra C2980104. superficial mycosis A fungal infectious disease that results_in infection of the outermost layer located_in skin or located_in hair shaft, has_material_basis_in Fungi. No living tissue is invaded and there is no cellular response from the host. url:http://en.wikipedia.org/wiki/Mycoses url:http://www.mycology.adelaide.edu.au/Mycoses/ A fungal infectious disease that results_in infection of the keratinized layers located_in skin, located_in hair or located_in nail, which extends deeper into the epidermis, has_material_basis_in Fungi and results_in_formation_of skin lesions. disease_ontology DOID:0050134 cutaneous mycosis A fungal infectious disease that results_in infection of the keratinized layers located_in skin, located_in hair or located_in nail, which extends deeper into the epidermis, has_material_basis_in Fungi and results_in_formation_of skin lesions. url:http://en.wikipedia.org/wiki/Mycoses url:http://jama.ama-assn.org/cgi/reprint/61/6/407 A fungal infectious disease that results_in infection located_in skin or located_in subcutaneous tissue, has_material_basis_in Fungi, which penetrate the dermis or even deeper during or after a skin trauma. disease_ontology DOID:0050135 subcutaneous mycosis A fungal infectious disease that results_in infection located_in skin or located_in subcutaneous tissue, has_material_basis_in Fungi, which penetrate the dermis or even deeper during or after a skin trauma. url:https://www.adelaide.edu.au/mycology/mycoses/subcutaneous-mycoses A fungal infectious disease that results_in infection of internal organs and tissues located_in human body, has_material_basis_in Fungi, which enter the body via the respiratory tract, through the gut, paranasal sinuses or skin and spread through the bloodstream to multiple organs. disease_ontology DOID:0050136 systemic mycosis A fungal infectious disease that results_in infection of internal organs and tissues located_in human body, has_material_basis_in Fungi, which enter the body via the respiratory tract, through the gut, paranasal sinuses or skin and spread through the bloodstream to multiple organs. url:http://dermnetnz.org/fungal/systemic-mycoses.html url:http://www.mycology.adelaide.edu.au/Mycoses/ url:http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mmed&part=A4006 An elephantiasis that is characterized by lymphadema located_in the lower extremities caused by a genetically determined abnormal inflammatory reaction to mineral particles in irritant red clay soils derived from volcanic deposits. MESH:D004604 disease_ontology DOID:0050138 podoconiosis An elephantiasis that is characterized by lymphadema located_in the lower extremities caused by a genetically determined abnormal inflammatory reaction to mineral particles in irritant red clay soils derived from volcanic deposits. url:https://en.wikipedia.org/wiki/Podoconiosis A opisthorchiasis that involves parasitic infection of the liver, biliary ducts, pancreas and pancreatic ducts by Opisthorchis felineus. The symptoms include fever, general malaise, skin rash, gastrointestinal disturbances, severe anemia and liver damage. disease_ontology DOID:0050139 obsolete Opisthorchis felineus infectious disease true A opisthorchiasis that involves parasitic infection of the liver, biliary ducts, pancreas and pancreatic ducts by Opisthorchis felineus. The symptoms include fever, general malaise, skin rash, gastrointestinal disturbances, severe anemia and liver damage. url:http://en.wikipedia.org/wiki/Opisthorchis_felineus A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. disease_ontology DOID:0050140 acute diarrhea A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. url:http://en.wikipedia.org/wiki/Diarrhea A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F) in adults, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F, which are transmitted by ingestion of bacterial spores, which then grow in the intestine and release toxins. disease_ontology DOID:0050141 intestinal botulism A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F) in adults, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F, which are transmitted by ingestion of bacterial spores, which then grow in the intestine and release toxins. url:http://www.who.int/mediacentre/factsheets/fs270/en/ url:https://jnnp.bmj.com/content/75/suppl_3/iii35 A dengue disease that results_in infection, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has no manifestations of symptoms. disease_ontology DOID:0050143 asymptomatic dengue A dengue disease that results_in infection, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has no manifestations of symptoms. url:https://pubmed.ncbi.nlm.nih.gov/28107858/ url:https://pubmed.ncbi.nlm.nih.gov/29111183/ A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development. GARD:6815 MESH:D007619 NCI:C84797 ORDO:98861 SNOMEDCT_US_2021_09_01:42402006 Kartagener's syndrome disease_ontology DOID:0050144 Kartagener syndrome A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development. url:http://en.wikipedia.org/wiki/Situs_inversus#Kartagener_syndrome url:https://www.ncbi.nlm.nih.gov/pubmed/19529061 url:https://www.ncbi.nlm.nih.gov/pubmed/23243352 url:https://www.ncbi.nlm.nih.gov/pubmed/24019633 url:https://www.ncbi.nlm.nih.gov/pubmed/25633235 An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing. DOID:13750 ICD10CM:J35.02 ICD9CM:474.01 SNOMEDCT_US_2023_03_01:195794009 UMLS_CUI:C0396023 chronic adenoiditis disease_ontology DOID:0050145 adenoiditis An upper respiratory tract disease which involves inflammation, pain, and swelling of the adenoid tissue due to the infection by bacteria and viruses. It occurs primarily in children and may be secondary to an allergy, infection of nose or throat and an obstruction of the eustachian tube. The infection has symptom pain, has symptom redness, has symptom swelling, and has symptom difficulty swallowing. url:http://books.google.com/books?id=6_BPQKPlYzcC&pg=PA96&lpg=PA96&dq#v=onepage&q=&f=false url:http://en.wikipedia.org/wiki/Adenoiditis An otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. It is characterized by inflammation, pruritus, scaling and severe discomfort. The most common fungi are Aspergillus niger and Candida albicans. MESH:D059249 Singapore ear disease_ontology DOID:0050147 otomycosis An otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. It is characterized by inflammation, pruritus, scaling and severe discomfort. The most common fungi are Aspergillus niger and Candida albicans. url:http://en.wikipedia.org/wiki/Otomycosis url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=otomycosis An upper respiratory tract disease involving inflammation of both larynx and trachea often caused by viral infection. The infection can close off the windpipe. DOID:11795 DOID:9390 ICD10CM:J04 ICD10CM:J37.1 ICD9CM:464 ICD9CM:476.1 SNOMEDCT_US_2023_03_01:276443001 SNOMEDCT_US_2023_03_01:83271005 UMLS_CUI:C0155811 UMLS_CUI:C0155837 disease_ontology DOID:0050148 laryngotracheitis An upper respiratory tract disease involving inflammation of both larynx and trachea often caused by viral infection. The infection can close off the windpipe. url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=laryngotracheitis A legionellosis that involves a milder respiratory illness without pneumonia. Symptoms include fever, headache and muscle aches which last for 2 to 5 days. disease_ontology DOID:0050150 Pontiac fever A legionellosis that involves a milder respiratory illness without pneumonia. Symptoms include fever, headache and muscle aches which last for 2 to 5 days. url:http://www.cdc.gov/legionella/patient_facts.htm url:https://www.ncbi.nlm.nih.gov/pubmed/623097 A pulmonary tuberculosis involving inflammation of trachea and bronchi. The symptoms include dry cough followed by dyspnea, localized wheezing, hemoptysis, hoarseness, anorexia, weight loss, chest pain and fever. disease_ontology DOID:0050151 obsolete tracheobronchial tuberculosis true A pulmonary tuberculosis involving inflammation of trachea and bronchi. The symptoms include dry cough followed by dyspnea, localized wheezing, hemoptysis, hoarseness, anorexia, weight loss, chest pain and fever. url:https://www.ncbi.nlm.nih.gov/pubmed/9122509 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has_symptom tachypnea and has_symptom cough. ICD10CM:J69.0 MESH:D011015 SNOMEDCT_US_2023_03_01:47839005 UMLS_CUI:C0032290 disease_ontology DOID:0050152 aspiration pneumonia A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has_symptom tachypnea and has_symptom cough. url:https://en.wikipedia.org/wiki/Aspiration_pneumonia An aspergillosis that presents as a clump of tangled mass of Aspergillus fungus fibres, blood clots, and white blood cells, which exists in the cavities of the lungs that develop in an area of previous lung disease or lung scarring. disease_ontology DOID:0050153 pulmonary aspergilloma An aspergillosis that presents as a clump of tangled mass of Aspergillus fungus fibres, blood clots, and white blood cells, which exists in the cavities of the lungs that develop in an area of previous lung disease or lung scarring. url:http://www.merck.com/mmhe/sec17/ch197/ch197b.html?qt=invasive%20pulmonary%20aspergillosis&alt=sh url:http://www.nlm.nih.gov/medlineplus/ency/article/001326.htm A bacterial pneumonia caused by the genus Mycoplasma. disease_ontology DOID:0050154 obsolete mycoplasmal pneumonia true A bacterial pneumonia caused by the genus Mycoplasma. url:http://en.wikipedia.org/wiki/Mycoplasma A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell). disease_ontology DOID:0050155 sensory system disease A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell). url:http://en.wikipedia.org/wiki/Sensory_system A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe. EFO:0000768 GARD:8609 ICD10CM:J84.112 ICD9CM:516.31 MESH:D054990 NCI:C35716 SNOMEDCT_US_2023_03_01:28168000 UMLS_CUI:C1800706 FIBROCYSTIC PULMONARY DYSPLASIA IDIOPATHIC PULMONARY FIBROSIS, FAMILIAL cryptogenic fibrosing alveolitis disease_ontology DOID:0050156 OMIM mapping confirmed by DO. [SN]. idiopathic pulmonary fibrosis A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe. url:https://pubmed.ncbi.nlm.nih.gov/32855221/ url:https://www.ncbi.nlm.nih.gov/books/NBK448162/ url:https://www.nhlbi.nih.gov/health/idiopathic-pulmonary-fibrosis url:https://www.pulmonaryfibrosis.org/life-with-pf/about-ipf An idiopathic interstitial pneumonia characterized by lung inflammation and scarring that obstructs the small airways and air sacs of the lungs (alveoli). A flu-like illness, with a cough, fever, a feeling of illness (malaise), fatigue, and weight loss, heralds the onset in about 50% of people. Frequent presence of crackling sounds (called Velcro crackles) when the doctor listens with a stethoscope. DOID:2798 GARD:1620 ICD10CM:J84.116 ICD9CM:516.36 MESH:D018549 NCI:C62586 SNOMEDCT_US_2023_03_01:129458007 UMLS_CUI:C0242770 BOOP Cryptogenic organising pneumonitis Cryptogenic organizing pneumonitis bronchiolitis obliterans organising pneumonia bronchiolitis obliterans organizing pneumonia cryptogenic organising pneumonia idiopathic bronchiolitis obliterans with organising pneumonia idiopathic bronchiolitis obliterans with organizing pneumonia disease_ontology DOID:0050157 cryptogenic organizing pneumonia An idiopathic interstitial pneumonia characterized by lung inflammation and scarring that obstructs the small airways and air sacs of the lungs (alveoli). A flu-like illness, with a cough, fever, a feeling of illness (malaise), fatigue, and weight loss, heralds the onset in about 50% of people. Frequent presence of crackling sounds (called Velcro crackles) when the doctor listens with a stethoscope. url:http://www.merck.com/mmhe/sec04/ch050/ch050b.html?qt=idiopathic%20interstitial%20pneumonia&alt=sh url:https://www.ncbi.nlm.nih.gov/pubmed/11790668 BOOP An idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation. DOID:2796 ICD10CM:J84.117 ICD9CM:516.37 MESH:C562470 MIM:263000 NCI:C35288 SNOMEDCT_US_2023_03_01:8549006 UMLS_CUI:C0238378 RBILD familial desquamative interstitial pneumonitis respiratory bronchiolitis-associated interstitial lung disease disease_ontology DOID:0050158 OMIM mapping confirmed by DO. [SN]. desquamative interstitial pneumonia An idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation. url:http://www.merck.com/mmhe/sec04/ch050/ch050b.html?qt=idiopathic%20interstitial%20pneumonia&alt=sh url:https://www.ncbi.nlm.nih.gov/pubmed/11790668 url:https://www.ncbi.nlm.nih.gov/pubmed/16142185 url:https://www.ncbi.nlm.nih.gov/pubmed/16456642 url:https://www.ncbi.nlm.nih.gov/pubmed/23001799 RBILD An idiopathic interstitial pneumonia which involves diffuse interstitial infiltration of involved areas mostly with T lymphocytes, plasma cells, and macrophages. Lymphoid hyperplasia is frequently seen. Onset is often slow with gradually increasing cough and breathlessness over 3 or more years. Fever, weight loss, chest pain, and arthralgia are occasionally found. Crackles may be detected as the disease progresses. MESH:C562489 disease_ontology DOID:0050159 lymphoid interstitial pneumonia An idiopathic interstitial pneumonia which involves diffuse interstitial infiltration of involved areas mostly with T lymphocytes, plasma cells, and macrophages. Lymphoid hyperplasia is frequently seen. Onset is often slow with gradually increasing cough and breathlessness over 3 or more years. Fever, weight loss, chest pain, and arthralgia are occasionally found. Crackles may be detected as the disease progresses. url:https://www.ncbi.nlm.nih.gov/pubmed/11790668 An anthrax disease that results in infection located in lung lymph nodes brought on by breathing in the spores of the bacteria Bacillus anthracis. The first symptoms of inhalation anthrax are like cold or flu symptoms and can include a sore throat, mild fever and muscle aches. Later symptoms include cough, chest discomfort, shortness of breath, tiredness and muscle aches. MESH:C571912 pulmonary anthrax respiratory anthrax wool-sorters' disease woolsorters' disease disease_ontology DOID:0050160 inhalation anthrax An anthrax disease that results in infection located in lung lymph nodes brought on by breathing in the spores of the bacteria Bacillus anthracis. The first symptoms of inhalation anthrax are like cold or flu symptoms and can include a sore throat, mild fever and muscle aches. Later symptoms include cough, chest discomfort, shortness of breath, tiredness and muscle aches. url:https://medlineplus.gov/ency/article/001325.htm url:https://www.cdc.gov/anthrax/basics/types/index.html url:https://www.ncbi.nlm.nih.gov/pubmed/11988441 A respiratory system disease which involves the lower respiratory tract. ICD9CM:478.19 SNOMEDCT_US_2023_03_01:195823002 UMLS_CUI:C0029581 disease_ontology DOID:0050161 lower respiratory tract disease A respiratory system disease which involves the lower respiratory tract. url:http://en.wikipedia.org/wiki/lower_respiratory_tract disease_ontology DOID:0050162 obsolete influenza encephalopathy true disease_ontology DOID:0050163 obsolete influenza myocarditis true disease_ontology DOID:0050164 obsolete influenza myositis true A tuberculosis that involves infection of the mesenteric glands by tuberculosis causing mycobacteria. The symptoms include distended abdomen, persistent intestinal indigestion, diarrhea, flatulence, and abdominal pain. disease_ontology DOID:0050165 obsolete tuberculous mesenteric gland true A tuberculosis that involves infection of the mesenteric glands by tuberculosis causing mycobacteria. The symptoms include distended abdomen, persistent intestinal indigestion, diarrhea, flatulence, and abdominal pain. url:http://books.google.com/books?id=130IVak1eCwC&pg=PA694&lpg=PA694&dq#v=onepage&q=&f=false An urogenital tuberculosis that results_in formation of granulomas located_in fallopian tube. ICD10CM:A18.17 ICD9CM:016.6 SNOMEDCT_US_2023_03_01:186242002 UMLS_CUI:C0152828 disease_ontology DOID:0050166 tuberculous salpingitis An urogenital tuberculosis that results_in formation of granulomas located_in fallopian tube. url:http://books.google.com/books?id=tuKGMxGRKa8C&pg=PA627&lpg=PA627&dq#v=onepage&q&f=false An autoimmune polyendocrine syndrome that is inherited in an autosomal recessive fashion, which is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. GARD:8466 MIM:240300 Autoimmune Polyglandular Syndrome I Whitaker syndrome autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy disease_ontology DOID:0050167 autoimmune polyendocrine syndrome type 1 An autoimmune polyendocrine syndrome that is inherited in an autosomal recessive fashion, which is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. url:https://rarediseases.info.nih.gov/diseases/8466/autoimmune-polyglandular-syndrome-type-1 sn:IEDB An autoimmune polyendocrine syndrome that is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. It is more heterogeneous and has not been linked to one gene. GARD:7611 MIM:269200 Schmidt syndrome disease_ontology DOID:0050168 autoimmune polyendocrine syndrome type 2 An autoimmune polyendocrine syndrome that is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. It is more heterogeneous and has not been linked to one gene. url:http://en.wikipedia.org/wiki/Autoimmune_polyendocrine_syndrome_type_2 sn:IEDB A lupus erythematosus that causes skin lesions on parts of the body that are exposed to sunlight. GARD:6225 disease_ontology DOID:0050169 cutaneous lupus erythematosus A lupus erythematosus that causes skin lesions on parts of the body that are exposed to sunlight. url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927537/ sn:IEDB A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Jamestown Canyon virus, which is transmitted_by Culiseta, transmitted_by Aedes, and transmitted_by Anopheles species of mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom neck stiffness, has_symptom photophobia, has_symptom nausea, has_symptom vomiting, and has_symptom seizures. disease_ontology DOID:0050170 obsolete Jamestown Canyon encephalitis true A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Jamestown Canyon virus, which is transmitted_by Culiseta, transmitted_by Aedes, and transmitted_by Anopheles species of mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom neck stiffness, has_symptom photophobia, has_symptom nausea, has_symptom vomiting, and has_symptom seizures. url:http://www.cdc.gov/ncidod/dvbid/arbor/arboguid.pdf url:https://www.ncbi.nlm.nih.gov/pubmed/10451169 A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Snowshoe hare virus, which is transmitted_by Aedes mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures. disease_ontology DOID:0050171 obsolete snowshoe hare encephalitis true A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Snowshoe hare virus, which is transmitted_by Aedes mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures. url:http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/07vol33/dr3311c-eng.php A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Trivittatus virus, which is transmitted_by Ochlerotatus trivittatus mosquito. The infection has_symptom headache, has_symptom fever, has_symptom disorientation, has_symptom tremors, has_symptom convulsions, has_symptom paralysis, and has_symptom coma. disease_ontology DOID:0050172 obsolete trivittatus encephalitis true A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Trivittatus virus, which is transmitted_by Ochlerotatus trivittatus mosquito. The infection has_symptom headache, has_symptom fever, has_symptom disorientation, has_symptom tremors, has_symptom convulsions, has_symptom paralysis, and has_symptom coma. url:http://books.google.com/books?id=GcvRX19C3C8C&pg=PA235&lpg#v=onepage&q=&f=false url:http://www.epi.state.nc.us/epi/gcdc/manual/casedefs/ENCEPHALITIS,ARBOVIRAL_CD.pdf url:http://www.health.state.ny.us/diseases/communicable/arboviral/fact_sheet.htm url:https://www.ncbi.nlm.nih.gov/pubmed/10025535 A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Inkoo virus, which is transmitted_by Ochlerotatus communis mosquito. The infection has_symptom stiff neck, has_symptom lethargy, has_symptom headache, has_symptom fever, and has_symptom seizures. disease_ontology DOID:0050173 obsolete inkoo encephalitis true A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Inkoo virus, which is transmitted_by Ochlerotatus communis mosquito. The infection has_symptom stiff neck, has_symptom lethargy, has_symptom headache, has_symptom fever, and has_symptom seizures. url:http://birdflubook.com/resources/0Kallio-Kokkoxxx.pdf url:http://en.wikipedia.org/wiki/California_encephalitis_virus url:http://www.ncbi.nlm.nih.gov/sites/entrez/8760424 url:https://www.ncbi.nlm.nih.gov/pubmed/10025535 A West Nile encephalitis that results_in infection located_in brain, has_material_basis_in Kunjin virus, a subtype of West Nile Virus, which is transmitted_by Culex annulirostris mosquito bite. The infection has_symptom fever, has_symptom rigor, has_symptom headache, has_symptom confusion, and has_symptom lethargy. disease_ontology DOID:0050174 Kunjin encephalitis A West Nile encephalitis that results_in infection located_in brain, has_material_basis_in Kunjin virus, a subtype of West Nile Virus, which is transmitted_by Culex annulirostris mosquito bite. The infection has_symptom fever, has_symptom rigor, has_symptom headache, has_symptom confusion, and has_symptom lethargy. url:http://www.ncbi.nlm.nih.gov/sites/entrez/2552010 url:https://www.health.nsw.gov.au/Infectious/factsheets/Pages/kunjin_virus.aspx A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Tick-borne encephalitis virus, which is transmitted_by Ixodes ticks. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis. DOID:0050176 DOID:10251 DOID:10252 GARD:5216 ICD10CM:A84.1 ICD9CM:063.2 MESH:D004675 SNOMEDCT_US_2023_03_01:16901001 UMLS_CUI:C0014054 Central European encephalitis Far Eastern TBE Russian spring-summer encephalitis Siberian tick-borne encephalitis Taiga encephalitis Western European tick-borne encephalitis west-Siberian encephalitis disease_ontology DOID:0050175 tick-borne encephalitis A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Tick-borne encephalitis virus, which is transmitted_by Ixodes ticks. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis. url:http://www.cdc.gov/ncidod/dvrd/Spb/mnpages/dispages/TBE.htm A genetic disease that is the result of one or more abnormal alleles and may be dominant, semi-dominant, or recessive. disease_ontology DOID:0050177 monogenic disease A genetic disease that is the result of one or more abnormal alleles and may be dominant, semi-dominant, or recessive. url:https://www.genome.gov/For-Patients-and-Families/Genetic-Disorders A genetic disease that require multiple abnormal alleles to manifest are complex. These diseases are termed multifactorial or polygenic. Expressivity or penetrance of the disease is complex and is associated with multiple genes in combination with lifestyle and environmental factors. Multifactoral genetic diseases include heart disease and diabetes, although a subset of diabetes may be classified as a monogenic disease (due to the presence of a single abnormal allele). disease_ontology DOID:0050178 obsolete complex genetic disease true A genetic disease that require multiple abnormal alleles to manifest are complex. These diseases are termed multifactorial or polygenic. Expressivity or penetrance of the disease is complex and is associated with multiple genes in combination with lifestyle and environmental factors. Multifactoral genetic diseases include heart disease and diabetes, although a subset of diabetes may be classified as a monogenic disease (due to the presence of a single abnormal allele). DO:wk A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Powassan virus, which is transmitted_by Ixodes and transmitted_by Dermacentor species of ticks. The infection has_symptom headache, has_symptom fever, has_symptom vomiting, has_symptom stiff neck, has_symptom sleepiness, has_symptom breathing distress, has_symptom tremors, has_symptom confusion, has_symptom seizures, has_symptom paralysis, and has_symptom coma. disease_ontology DOID:0050179 Powassan encephalitis A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Powassan virus, which is transmitted_by Ixodes and transmitted_by Dermacentor species of ticks. The infection has_symptom headache, has_symptom fever, has_symptom vomiting, has_symptom stiff neck, has_symptom sleepiness, has_symptom breathing distress, has_symptom tremors, has_symptom confusion, has_symptom seizures, has_symptom paralysis, and has_symptom coma. url:https://www.ncbi.nlm.nih.gov/articles/PMC5732952/ A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Colorado tick fever virus which is transmitted_by rocky mountain wood tick, Dermacentor andersoni. The infection has_symptom fever, has_symptom headache, has_symptom nausea, has_symptom stiff neck, has_symptom chills, has_symptom hallucinations, has_symptom disorientation, and has_symptom memory loss. disease_ontology DOID:0050180 obsolete Colorado tick fever encephalitis true A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Colorado tick fever virus which is transmitted_by rocky mountain wood tick, Dermacentor andersoni. The infection has_symptom fever, has_symptom headache, has_symptom nausea, has_symptom stiff neck, has_symptom chills, has_symptom hallucinations, has_symptom disorientation, and has_symptom memory loss. url:http://www.ncbi.nlm.nih.gov/sites/entrez/2838146 url:https://www.ncbi.nlm.nih.gov/pubmed/13894744 A Simplexvirus infectious disease that results_in infection located_in brain, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2. The infection has_symptom headache, has_symptom fever, has_symptom personality and behavioral changes, has_symptom seizures, has_symptom partial paralysis, and has_symptom hallucinations. disease_ontology DOID:0050181 obsolete Herpes simplex virus encephalitis true A Simplexvirus infectious disease that results_in infection located_in brain, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2. The infection has_symptom headache, has_symptom fever, has_symptom personality and behavioral changes, has_symptom seizures, has_symptom partial paralysis, and has_symptom hallucinations. url:http://www.ninds.nih.gov/disorders/encephalitis_meningitis/detail_encephalitis_meningitis.htm A Varicellovirus infectious disease that results_in infection located_in brain, has_material_basis_in Human herpesvirus 3 and has_symptom lethargy, has_symptom rash, has_symptom confusion, has_symptom hallucinations, has_symptom weakness, has_symptom paralysis, has_symptom numbness, and has_symptom parasthesias. DOID:8698 Herpes zoster encephalitis Postchickenpox encephalitis Varicella Zoster Encephalitis postvaricella encephalitis disease_ontology DOID:0050182 obsolete Varicella-zoster virus encephalitis true A Varicellovirus infectious disease that results_in infection located_in brain, has_material_basis_in Human herpesvirus 3 and has_symptom lethargy, has_symptom rash, has_symptom confusion, has_symptom hallucinations, has_symptom weakness, has_symptom paralysis, has_symptom numbness, and has_symptom parasthesias. url:http://journals.lww.com/infectdis/Fulltext/2007/07000/Herpes_Zoster_Encephalitis__2_Case_Reports_and.19.aspx url:https://www.ncbi.nlm.nih.gov/pubmed/6273449 An Epstein-Barr virus infectious disease that results_in inflammation, located_in brain, has_material_basis_in Human herpesvirus 4 and has_symptom seizures, has_symptom altered consciousness, and has_symptom cerebellar ataxia. disease_ontology DOID:0050183 obsolete Epstein-Barr virus encephalitis true An Epstein-Barr virus infectious disease that results_in inflammation, located_in brain, has_material_basis_in Human herpesvirus 4 and has_symptom seizures, has_symptom altered consciousness, and has_symptom cerebellar ataxia. url:http://www.aafp.org/afp/20000201/letters.html url:http://www.cdc.gov/ncidod/eid/vol9no2/02-0218.htm A Measles virus infectious disease that results_in inflammation located_in brain, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom headache, has_symptom irritability, has_symptom drowsiness, has_symptom abnormal reflexes, has_symptom involuntary movements, has_symptom hemiplagia, has_symptom ataxia, has_symptom nystagmus, and has_symptom dysphasia. DOID:9127 Post measles encephalitis (disorder) Post-measles encephalitis postmeasles encephalitis disease_ontology DOID:0050184 obsolete Measles virus encephalitis true A Measles virus infectious disease that results_in inflammation located_in brain, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom headache, has_symptom irritability, has_symptom drowsiness, has_symptom abnormal reflexes, has_symptom involuntary movements, has_symptom hemiplagia, has_symptom ataxia, has_symptom nystagmus, and has_symptom dysphasia. url:http://www.nature.com/nrneurol/journal/v5/n3/full/ncpneuro1043.html url:http://www.springerlink.com/content/2020124072032058/ A skin disease that is a type of allergic reaction located_in skin, which occurs in response to medications, infections, or illness. GARD:6372 MESH:D004892 disease_ontology DOID:0050185 erythema multiforme A skin disease that is a type of allergic reaction located_in skin, which occurs in response to medications, infections, or illness. url:http://www.nlm.nih.gov/medlineplus/ency/article/000851.htm A Cytomegalovirus infectious disease that results_in inflammation, located_in brain, has_material_basis_in Human herpesvirus 5, has_symptom confusional syndrome, has_symptom seizures, has_symptom coma, has_symptom dysphasia, and has_symptom cranial nerve palsies. disease_ontology DOID:0050186 obsolete Cytomegalovirus encephalitis true A Cytomegalovirus infectious disease that results_in inflammation, located_in brain, has_material_basis_in Human herpesvirus 5, has_symptom confusional syndrome, has_symptom seizures, has_symptom coma, has_symptom dysphasia, and has_symptom cranial nerve palsies. url:https://www.ncbi.nlm.nih.gov/pubmed/8815757 A Rubella virus infectious disease that results_in inflammation located_in brain, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom confusion, has_symptom drowsiness, has_symptom delirium, has_symptom convulsions, has_symptom cranial nerve palsies, and has_symptom coma. DOID:9231 disease_ontology DOID:0050187 obsolete Rubella virus encephalitis true A Rubella virus infectious disease that results_in inflammation located_in brain, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom confusion, has_symptom drowsiness, has_symptom delirium, has_symptom convulsions, has_symptom cranial nerve palsies, and has_symptom coma. url:http://www.ncbi.nlm.nih.gov/sites/entrez/13489263 An Enterovirus infectious disease that involves inflammation located_in brain, has_material_basis_in group A coxsackievirus or has_material_basis_in group B coxsackievirus, which are transmitted_by ingestion of food contaminated with feces, transmitted_by contact with pharyngeal secretions, or transmitted_by droplet spread of oronasal secretions. The infection has_symptom reduced level of consciousness, has_symptom confusion, has_symptom irritability, has_symptom seizures, and has_symptom coma. disease_ontology DOID:0050188 obsolete coxsackievirus encephalitis true An Enterovirus infectious disease that involves inflammation located_in brain, has_material_basis_in group A coxsackievirus or has_material_basis_in group B coxsackievirus, which are transmitted_by ingestion of food contaminated with feces, transmitted_by contact with pharyngeal secretions, or transmitted_by droplet spread of oronasal secretions. The infection has_symptom reduced level of consciousness, has_symptom confusion, has_symptom irritability, has_symptom seizures, and has_symptom coma. url:https://www.ncbi.nlm.nih.gov/pubmed/14464001 An Enterovirus infectious disease that results_in inflammation located_in brain, has_material_basis_in polioviruses, which are transmitted_by ingestion of food contaminated with feces. The infection has_symptom tremors, has_symptom nystagmus, has_symptom loss of conjugate eye movements, has_symptom muscle rigidity, has_symptom hemiparesis, and has_symptom coma. disease_ontology DOID:0050189 obsolete polioencephalitis true An Enterovirus infectious disease that results_in inflammation located_in brain, has_material_basis_in polioviruses, which are transmitted_by ingestion of food contaminated with feces. The infection has_symptom tremors, has_symptom nystagmus, has_symptom loss of conjugate eye movements, has_symptom muscle rigidity, has_symptom hemiparesis, and has_symptom coma. url:https://www.ncbi.nlm.nih.gov/pubmed/13436875 An adenovirus infectious disease that results_in inflammation located_in brain, has_material_basis_in Human adenovirus 2 or has_material_basis_in Human adenovirus 4. The symptoms include fever, stupor, nuchal rigidity, loss of consciousness and seizures. disease_ontology DOID:0050190 obsolete adenovirus encephalitis true An adenovirus infectious disease that results_in inflammation located_in brain, has_material_basis_in Human adenovirus 2 or has_material_basis_in Human adenovirus 4. The symptoms include fever, stupor, nuchal rigidity, loss of consciousness and seizures. url:http://cid.oxfordjournals.org/content/31/3/830.full url:http://www.medscape.com/viewarticle/414625 url:https://www.ncbi.nlm.nih.gov/pubmed/15560392 A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Influenza A virus or has_material_basis_in Influenza B virus, which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. The infection has_symptom fever, has_symptom reduced consciousness, and has_symptom ocular muscle palsies. disease_ontology DOID:0050191 obsolete influenza virus encephalitis true A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Influenza A virus or has_material_basis_in Influenza B virus, which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. The infection has_symptom fever, has_symptom reduced consciousness, and has_symptom ocular muscle palsies. url:http://www.ncbi.nlm.nih.gov/sites/entrez/2053792 A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Nipah virus, which is transmitted_by direct contact with sick person or animals, or their contaminated tissues. The infection has_symptom dizziness, has_symptom drowsiness, has_symptom altered consciousness, has_symptom disorientation, and has_symptom coma. disease_ontology DOID:0050192 Nipah virus encephalitis A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Nipah virus, which is transmitted_by direct contact with sick person or animals, or their contaminated tissues. The infection has_symptom dizziness, has_symptom drowsiness, has_symptom altered consciousness, has_symptom disorientation, and has_symptom coma. url:https://www.cdc.gov/vhf/nipah/index.html url:https://www.ncbi.nlm.nih.gov/pubmed/19141846 url:https://www.who.int/csr/disease/nipah/en/ A lymphocytic choriomeningitis that results_in inflammation located_in brain, has_material_basis_in Lymphocytic choriomeningitis virus, which is transmitted_by common house mouse, Mus musculus. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis. disease_ontology DOID:0050193 obsolete Lymphocytic choriomeningitis virus encephalitis true A lymphocytic choriomeningitis that results_in inflammation located_in brain, has_material_basis_in Lymphocytic choriomeningitis virus, which is transmitted_by common house mouse, Mus musculus. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis. url:http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lcmv/qa.htm A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Junin virus, which is transmitted_by rodent, Calomys musculinus. The infection has_symptom fever, has_symptom fatigue, has_symptom malaise, has_symptom leukopenia, has_symptom thrombocytopenia, and has_symptom hemorrhagic manifestations. disease_ontology DOID:0050194 Argentine hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Junin virus, which is transmitted_by rodent, Calomys musculinus. The infection has_symptom fever, has_symptom fatigue, has_symptom malaise, has_symptom leukopenia, has_symptom thrombocytopenia, and has_symptom hemorrhagic manifestations. url:http://en.wikipedia.org/wiki/Argentine_hemorrhagic_fever url:http://www.jstor.org/stable/30129873?seq=1 A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus machupoense, which is transmitted_by vesper mouse, Calomys callosus. The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary tracts. disease_ontology DOID:0050195 Bolivian hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus machupoense, which is transmitted_by vesper mouse, Calomys callosus. The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary tracts. url:http://www.cdc.gov/ncidod/eid/vol1no3/kilgore.htm A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus guanaritoense, which is transmitted_by cotton rat, Sigmodon alstoni or transmitted_by cane mouse, Zygodontomys brevicauda. The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom sore throat, has_symptom weakness, has_symptom anorexia, has_symptom nausea, has_symptom vomiting, has_symptom convulsions, has_symptom epistaxis, has_symptom bleeding gums, has_symptom hematemesis, has_symptom melena, and has_symptom menorrhagia. disease_ontology DOID:0050196 Venezuelan hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus guanaritoense, which is transmitted_by cotton rat, Sigmodon alstoni or transmitted_by cane mouse, Zygodontomys brevicauda. The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom sore throat, has_symptom weakness, has_symptom anorexia, has_symptom nausea, has_symptom vomiting, has_symptom convulsions, has_symptom epistaxis, has_symptom bleeding gums, has_symptom hematemesis, has_symptom melena, and has_symptom menorrhagia. url:https://pubmed.ncbi.nlm.nih.gov/34917387/ url:https://pubmed.ncbi.nlm.nih.gov/7840443/ A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus brazilense, which is transmitted by rodents. The infection has symptom fever, has symptom eye redness, has symptom fatigue, has symptom dizziness, has symptom muscle aches, has symptom loss of strength, and has symptom bleeding under the skin, internal organs, or from body orifices like the mouth, eyes or ears. disease_ontology DOID:0050197 Brazilian hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus brazilense, which is transmitted by rodents. The infection has symptom fever, has symptom eye redness, has symptom fatigue, has symptom dizziness, has symptom muscle aches, has symptom loss of strength, and has symptom bleeding under the skin, internal organs, or from body orifices like the mouth, eyes or ears. url:http://en.wikipedia.org/wiki/Brazilian_hemorrhagic_fever url:http://www.ncbi.nlm.nih.gov/sites/entrez/18421377 url:https://www.ncbi.nlm.nih.gov/pubmed/7905555 A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus chapareense. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom shock, and has symptom bleeding. disease_ontology DOID:0050198 Chapare hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus chapareense. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom shock, and has symptom bleeding. url:http://www.ncbi.nlm.nih.gov/sites/entrez/18421377 A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus whitewaterense, which is transmitted_by white-throated woodrats (Neotoma albigula). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, and has_symptom hemorrhagic manifestations. disease_ontology DOID:0050199 Whitewater Arroyo hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Mammarenavirus whitewaterense, which is transmitted_by white-throated woodrats (Neotoma albigula). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, and has_symptom hemorrhagic manifestations. url:http://jama.ama-assn.org/cgi/content/full/284/10/1237 url:http://www.ncbi.nlm.nih.gov/sites/entrez/1799746 A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload. disease_ontology DOID:0050200 Korean hemorrhagic fever A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload. url:http://books.google.com/books?id=VS5bqBQ9RWoC&pg=PR65&lpg=PR65&dq#v=onepage&q&f=false url:http://www.cdc.gov/mmwr/preview/mmwrhtml/00051521.htm url:https://www.ncbi.nlm.nih.gov/pubmed/1349231 A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Orthohantavirus puumalaense, which is transmitted_by bank vole, Myodes glareolus [NCBITaxon:447135]. The infection has_symptom headache, has_symptom nausea, has_symptom back pain, has_symptom vomiting, has_symptom myalgia, has_symptom abdominal pain, has_symptom internal hemorrhage, and has_symptom renal failure. disease_ontology DOID:0050201 nephropathia epidemica A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Orthohantavirus puumalaense, which is transmitted_by bank vole, Myodes glareolus [NCBITaxon:447135]. The infection has_symptom headache, has_symptom nausea, has_symptom back pain, has_symptom vomiting, has_symptom myalgia, has_symptom abdominal pain, has_symptom internal hemorrhage, and has_symptom renal failure. url:https://www.ncbi.nlm.nih.gov/pubmed/1349231 url:https://www.ncbi.nlm.nih.gov/pubmed/2574903 url:https://www.ncbi.nlm.nih.gov/pubmed/2902106 A viral infectious disease that results_in infection, has_material_basis_in Lujo virus, which has_symptom bleeding. disease_ontology DOID:0050202 lujo hemorrhagic fever A viral infectious disease that results_in infection, has_material_basis_in Lujo virus, which has_symptom bleeding. url:http://www.ncbi.nlm.nih.gov/sites/entrez/19478873 A Cytomegalovirus infectious disease that results_in inflammation, located_in liver, has_material_basis_in Human herpesvirus 5, has_symptom nausea, has_symptom vomiting, has_symptom headache, has_symptom abdominal pain, has_symptom dark urine, and has_symptom jaundice. Clinical feature includes atypical lymphocytes in the blood. disease_ontology DOID:0050203 obsolete Cytomegalovirus hepatitis true A Cytomegalovirus infectious disease that results_in inflammation, located_in liver, has_material_basis_in Human herpesvirus 5, has_symptom nausea, has_symptom vomiting, has_symptom headache, has_symptom abdominal pain, has_symptom dark urine, and has_symptom jaundice. Clinical feature includes atypical lymphocytes in the blood. url:http://en.wikipedia.org/wiki/Cytomegalovirus url:http://www.ncbi.nlm.nih.gov/sites/entrez/11380800 url:https://www.ncbi.nlm.nih.gov/pubmed/4300216 A viral hepatitis that results_in inflammation, located_in liver, has_material_basis_in Human herpesvirus 4 and has_symptom headache, has_symptom fatigue, has_symptom fever, has_symptom abdominal pain, has_symptom nausea, and has_symptom jaundice. disease_ontology DOID:0050204 Epstein-Barr virus hepatitis A viral hepatitis that results_in inflammation, located_in liver, has_material_basis_in Human herpesvirus 4 and has_symptom headache, has_symptom fatigue, has_symptom fever, has_symptom abdominal pain, has_symptom nausea, and has_symptom jaundice. url:https://www.ncbi.nlm.nih.gov/pubmed/16711324 url:https://www.ncbi.nlm.nih.gov/pubmed/17602362 A Simplexvirus infectious disease that results_in inflammation located_in liver, has-agent Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, and has_symptom fever, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, and has_symptom herpetic lesions. disease_ontology DOID:0050205 obsolete Herpes simplex virus hepatitis true A Simplexvirus infectious disease that results_in inflammation located_in liver, has-agent Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, and has_symptom fever, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, and has_symptom herpetic lesions. url:http://jcp.bmj.com/content/46/10/968.full.pdf url:http://www.jstor.org/stable/20396832 url:https://www.ncbi.nlm.nih.gov/pubmed/16597901 url:https://www.ncbi.nlm.nih.gov/pubmed/7006542 An adenovirus infectious disease that involves inflammation of the liver caused by Human adenovirus 1, has_material_basis_in Human adenovirus 2, or has_material_basis_in Human adenovirus 5. The symptoms include fever, coagulopathy and gastrointestinal bleeding. Histopathological examination reveals widespread hepatic necrosis with hemorrhage. disease_ontology DOID:0050206 obsolete adenovirus hepatitis true A Rubella virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection results in hepatic necrosis. disease_ontology DOID:0050207 obsolete Rubella virus hepatitis true A Rubella virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection results in hepatic necrosis. url:http://books.google.com/books?id=739MM_WTJREC&pg=PA274&lpg#v=onepage&q=&f=false url:https://www.ncbi.nlm.nih.gov/pubmed/7550869 A Yellow fever virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Yellow fever virus. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, has_symptom weakness, has_symptom nausea, has_symptom vomiting, has_symptom jaundice, and has_symptom hemorrhagic manifestations. disease_ontology DOID:0050208 obsolete yellow fever hepatitis true A Yellow fever virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Yellow fever virus. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, has_symptom weakness, has_symptom nausea, has_symptom vomiting, has_symptom jaundice, and has_symptom hemorrhagic manifestations. url:http://books.google.com/books?id=739MM_WTJREC&pg=PA274&lpg#v=onepage&q=rubulavirus&f=false A Measles virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection causes hepatic dysfunction and has_symptom jaundice. disease_ontology DOID:0050209 obsolete Measles virus hepatitis true A Measles virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection causes hepatic dysfunction and has_symptom jaundice. url:http://books.google.com/books?id=739MM_WTJREC&pg=PA275&lpg#v=onepage&q=rubulavirus&f=false url:https://www.ncbi.nlm.nih.gov/pubmed/17068034 url:https://www.ncbi.nlm.nih.gov/pubmed/3417236 A Varicellovirus infectious disease that results_in inflammation located_in liver, has_material_basis_in Human herpesvirus 3, has_symptom skin rash, has_symptom oral lesions, has_symptom severe abdominal and back pain, has_symptom fever, has_symptom chills, has_symptom malaise, and has_symptom fatigue. disease_ontology DOID:0050210 obsolete Varicella-zoster virus hepatitis true A Varicellovirus infectious disease that results_in inflammation located_in liver, has_material_basis_in Human herpesvirus 3, has_symptom skin rash, has_symptom oral lesions, has_symptom severe abdominal and back pain, has_symptom fever, has_symptom chills, has_symptom malaise, and has_symptom fatigue. url:http://www.ncbi.nlm.nih.gov/sites/entrez/16944014 url:http://www.ncbi.nlm.nih.gov/sites/entrez/8092915 An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus, or has_material_basis_in Influenza A virus subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea. disease_ontology DOID:0050211 swine influenza An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus, or has_material_basis_in Influenza A virus subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea. url:https://www.cdc.gov/swine-flu/about/index.html url:https://www.ncbi.nlm.nih.gov/pubmed/9140195 A primary Campylobacter infectious disease that involves inflammation of the stomach and intestines caused by Campylobacter jejuni infection, which is characterized by diarrhea (may be bloody), abdominal pain, fever and vomiting. Campylobacter Gastroenteritis disease_ontology DOID:0050212 obsolete Campylobacter jejuni gastroenteritis true A primary Campylobacter infectious disease that involves inflammation of the stomach and intestines caused by Campylobacter jejuni infection, which is characterized by diarrhea (may be bloody), abdominal pain, fever and vomiting. url:https://www.ncbi.nlm.nih.gov/pubmed/17846438 A Vibrio infectious disease that involves inflammation of the stomach and intestines caused by noncholera Vibrio species like Vibrio parahaemolyticus, Vibrio fluvialis and Vibrio vulnificus. Some species produce enterotoxins, which impair intestinal absorption, resulting in watery diarrhea. The symptoms include abdominal cramps, fever, vomiting, nausea and diarrhea. disease_ontology DOID:0050213 obsolete Vibrio gastroenteritis true A Vibrio infectious disease that involves inflammation of the stomach and intestines caused by noncholera Vibrio species like Vibrio parahaemolyticus, Vibrio fluvialis and Vibrio vulnificus. Some species produce enterotoxins, which impair intestinal absorption, resulting in watery diarrhea. The symptoms include abdominal cramps, fever, vomiting, nausea and diarrhea. url:http://www.fda.gov/Food/FoodSafety/FoodborneIllness/FoodborneIllnessFoodbornePathogensNaturalToxins/BadBugBook/ucm070419.htm url:http://www.jstor.org/stable/pdfplus/30113106.pdf url:http://www.merck.com/mmpe/sec02/ch016/ch016a.html A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. ICD10CM:G70.80 ICD9CM:358.3 MESH:D015624 NCI:C3155 SNOMEDCT_US_2023_03_01:230688006 UMLS_CUI:C0022972 Eaton-Lambert syndrome LEMS Lambert-Eaton syndrome disease_ontology DOID:0050214 Lambert-Eaton myasthenic syndrome A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. url:http://en.wikipedia.org/wiki/Lambert%E2%80%93Eaton_myasthenic_syndrome LEMS A staphylococcal infectious disease that is caused by ingestion of food containing enterotoxins, which are produced by staphylococcal species. The symptoms include abdominal cramps, diarrhea, headache and fever. Staphylococcus Aureus Gastroenteritis disease_ontology DOID:0050215 obsolete Staphylococcus gastroenteritis true A staphylococcal infectious disease that is caused by ingestion of food containing enterotoxins, which are produced by staphylococcal species. The symptoms include abdominal cramps, diarrhea, headache and fever. url:http://www.merck.com/mmhe/sec09/ch122/ch122c.html url:http://www.springerlink.com/content/pg45520138llh128/ A primary Bacillaceae infectious disease that is caused by ingestion of food contaminated with Bacillus cereus, which produces enterotoxins in the intestine. The symptoms include vomiting, abdominal cramps, fever and diarrhea. disease_ontology DOID:0050216 obsolete Bacillus cereus gastroenteritis true A primary Bacillaceae infectious disease that is caused by ingestion of food contaminated with Bacillus cereus, which produces enterotoxins in the intestine. The symptoms include vomiting, abdominal cramps, fever and diarrhea. url:http://www.jstor.org/stable/pdfplus/30112755.pdf url:https://www.ncbi.nlm.nih.gov/pubmed/8501338 A viral infectious disease that results_in inflammation located_in stomach and located_in intestine, has_material_basis_in Sapovirus, which is transmitted_by ingestion of contaminated food. The infection has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, and has_symptom diarrhea. disease_ontology DOID:0050217 obsolete Sapovirus gastroenteritis true A viral infectious disease that results_in inflammation located_in stomach and located_in intestine, has_material_basis_in Sapovirus, which is transmitted_by ingestion of contaminated food. The infection has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, and has_symptom diarrhea. url:http://www.cdc.gov/ncidod/dvrd/revb/gastro/norovirus-factsheet.htm url:http://www0.nih.go.jp/JJID/61/438.pdf An echinococcosis that is caused by the larvae of Echinococcus vogeli or Echinococcus oligarthrus, which infect the liver. human polycystic hydatid disease neotropical echinococcosis disease_ontology DOID:0050218 polycystic echinococcosis An echinococcosis that is caused by the larvae of Echinococcus vogeli or Echinococcus oligarthrus, which infect the liver. url:http://en.wikipedia.org/wiki/Echinococcosis url:http://www.dpd.cdc.gov/dpdx/HTML/Echinococcosis.htm A (+)ssRNA virus infectious disease that results_in infection in animals and humans, located_in liver, has_material_basis_in Hepeviridae viruses. disease_ontology DOID:0050219 obsolete Hepeviridae infectious disease true A (+)ssRNA virus infectious disease that results_in infection in animals and humans, located_in liver, has_material_basis_in Hepeviridae viruses. url:http://en.wikipedia.org/wiki/Hepeviridae url:http://www.expasy.org/viralzone/all_by_species/41.html A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission. Q fever pneumonia disease_ontology DOID:0050220 obsolete Coxiella burnetii pneumonia true A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission. url:http://en.wikipedia.org/wiki/Q_fever url:https://www.ncbi.nlm.nih.gov/pubmed/15021054 A Q fever that involves inflammation of the liver caused by Coxiella burnetti, which results in the formation of granulomas. The symptoms include fever, malaise, hepatomegaly with right upper abdominal pain, and jaundice. Q fever hepatitis disease_ontology DOID:0050221 obsolete Coxiella burnetii hepatitis true A Q fever that involves inflammation of the liver caused by Coxiella burnetti, which results in the formation of granulomas. The symptoms include fever, malaise, hepatomegaly with right upper abdominal pain, and jaundice. url:http://www.merck.com/mmpe/sec14/ch177/ch177i.html A selective immunoglobulin deficiency disease thatis a dysgammaglobulinemia resulting from decreased levels of immunoglobulin M (IgM) production to roduction of other antibodies. disease_ontology DOID:0050222 selective IgM deficiency disease A selective immunoglobulin deficiency disease thatis a dysgammaglobulinemia resulting from decreased levels of immunoglobulin M (IgM) production to roduction of other antibodies. url:http://en.wikipedia.org/wiki/IgM url:http://en.wikipedia.org/wiki/Isolated_primary_immunoglobulin_M_deficiency A candidiasis that involves inflammation of the gastric mucosa caused by Candida albicans infection. The symptoms include dyspepsia, gastric ulcers, gastric perforations, nausea and vomiting. disease_ontology DOID:0050223 obsolete candidal gastritis true A primary Helicobacter infectious disease that involves inflammation of the stomach lining caused by Candidatus Helicobacter heilmannii, which is associated with peptic ulceration. disease_ontology DOID:0050224 obsolete Helicobacter heilmannii infectious disease true A primary Helicobacter infectious disease that involves inflammation of the stomach lining caused by Candidatus Helicobacter heilmannii, which is associated with peptic ulceration. url:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1731280/pdf/v054p00774.pdf url:https://www.ncbi.nlm.nih.gov/pubmed/10349993 An American histoplasmosis that results_in inflammation, located_in stomach lining in immunocompromised patients, has_material_basis_in Histoplasma capsulatum var capsulatum, transmitted_by airborne spores and results_in_formation_of gastric mass with ulceration, and results_in_formation_of hypertrophic gastric folds. disease_ontology DOID:0050225 obsolete Histoplasma capsulatum gastritis true An American histoplasmosis that results_in inflammation, located_in stomach lining in immunocompromised patients, has_material_basis_in Histoplasma capsulatum var capsulatum, transmitted_by airborne spores and results_in_formation_of gastric mass with ulceration, and results_in_formation_of hypertrophic gastric folds. url:http://www.merck.com/mmpe/sec02/ch013/ch013c.html url:http://www.ncbi.nlm.nih.gov/sites/entrez/16377536 An opportunistic bacterial infectious disease that involves infection of the intestine caused by Morganella morganii. disease_ontology DOID:0050226 obsolete Morganella morganii intestinal infectious disease true An opportunistic bacterial infectious disease that involves infection of the intestine caused by Morganella morganii. url:http://www.ncbi.nlm.nih.gov/sites/entrez/17180585 A cholera that involves infection of the intestine caused by Vibrio cholerae O139 strain. disease_ontology DOID:0050227 obsolete Vibrio cholerae O139 cholera true A cholera that involves infection of the intestine caused by Vibrio cholerae O139 strain. url:http://www.cdc.gov/nczved/divisions/dfbmd/diseases/cholera/technical.html#agent An amebiasis that involves infection of the intestine with Entamoeba histolytica trophozoites, which adhere to and kill colonic epithelial cells causing diarrhea with blood and mucus. The symptoms inlcude abdominal pain and fever. Entamoeba histolytica dysentery amebic dysentery amoebic dysentery disease_ontology DOID:0050228 obsolete amebic dysentery true An amebiasis that involves infection of the intestine with Entamoeba histolytica trophozoites, which adhere to and kill colonic epithelial cells causing diarrhea with blood and mucus. The symptoms inlcude abdominal pain and fever. url:http://www.merck.com/mmpe/sec14/ch185/ch185b.html An enteroinvasive Escherichia coli infectious disease that involves infection of the intestine caused by enteroinvasive Escherichia coli. The symptoms include fever, bloody diarrhea, and dehydration. disease_ontology DOID:0050229 obsolete Escherichia coli dysentery true An enteroinvasive Escherichia coli infectious disease that involves infection of the intestine caused by enteroinvasive Escherichia coli. The symptoms include fever, bloody diarrhea, and dehydration. url:http://emedicine.medscape.com/article/217485-overview url:http://www.jstor.org/stable/pdfplus/30112505.pdf A capillariasis that involves infection of the intestine with Capillaria causing abdominal pain, weight loss, stomach growling, depressed levels of potassium and albumin in the blood, and diarrhea. disease_ontology DOID:0050230 obsolete intestinal capillariasis true A capillariasis that involves infection of the intestine with Capillaria causing abdominal pain, weight loss, stomach growling, depressed levels of potassium and albumin in the blood, and diarrhea. url:http://en.wikipedia.org/wiki/Intestinal_capillariasis url:http://www.dpd.cdc.gov/DPDx/HTML/Capillariasis.htm A capillariasis that involves infection of the liver with Capillaria, which manifests as an acute or subacute hepatitis with eosinophilia. The symptoms include abdominal pain, fever, chills, hepatitis, ascites, hepatolithiasis, and hepatomegaly. disease_ontology DOID:0050231 obsolete hepatic capillariasis true A capillariasis that involves infection of the liver with Capillaria, which manifests as an acute or subacute hepatitis with eosinophilia. The symptoms include abdominal pain, fever, chills, hepatitis, ascites, hepatolithiasis, and hepatomegaly. url:http://en.wikipedia.org/wiki/Capillaria_hepatica url:http://www.dpd.cdc.gov/DPDx/HTML/Capillariasis.htm A capillariasis that involves infection of the lungs with Capillaria, resulting in fever, cough, asthma, and pneumonia. disease_ontology DOID:0050232 obsolete pulmonary capillariasis true A capillariasis that involves infection of the lungs with Capillaria, resulting in fever, cough, asthma, and pneumonia. url:http://www.dpd.cdc.gov/DPDx/HTML/Capillariasis.htm A parasitic protozoa infectious disease that involves infection caused by a free-living ameba Balamuthia mandrillaris resulting in encephalitis and skin lesions in humans and animals. disease_ontology DOID:0050233 obsolete Balamuthia mandrillaris infectious disease true A parasitic protozoa infectious disease that involves infection caused by a free-living ameba Balamuthia mandrillaris resulting in encephalitis and skin lesions in humans and animals. url:http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5728a2.htm A parasitic protozoa infectious disease that involves an infection in humans and animals caused by a parasitic protozoan of genus Acanthamoeba, which is an opportunistic pathogen occuring in patients with weakened immune system. DOID:11334 free-living ameba infectious disease disease_ontology DOID:0050234 obsolete Acanthamoeba infectious disease true A parasitic protozoa infectious disease that involves an infection in humans and animals caused by a parasitic protozoan of genus Acanthamoeba, which is an opportunistic pathogen occuring in patients with weakened immune system. url:http://en.wikipedia.org/wiki/Acanthamoeba A parasitic protozoa infectious disease that involves infection caused by alveolates, which are single-celled eukaryotes. disease_ontology DOID:0050235 obsolete Alveolata infectious disease true A parasitic protozoa infectious disease that involves infection caused by alveolates, which are single-celled eukaryotes. url:http://en.wikipedia.org/wiki/Alveolata A parasitic protozoa infectious disease that involves infection caused by the members of the class Heterolobosea, which move with eruptive bulges and show transformation to a temporary flagellate stage. disease_ontology DOID:0050236 obsolete Heterolobosea infectious disease true A parasitic protozoa infectious disease that involves infection caused by the members of the class Heterolobosea, which move with eruptive bulges and show transformation to a temporary flagellate stage. url:http://tolweb.org/Heterolobosea/96360 A parasitic protozoa infectious disease that involves infection caused by euglenozoans, which are single-celled flagellates. disease_ontology DOID:0050237 obsolete Euglenozoa infectious disease true A parasitic protozoa infectious disease that involves infection caused by euglenozoans, which are single-celled flagellates. url:http://en.wikipedia.org/wiki/Euglenozoa A parasitic protozoa infectious disease that involves infection caused by parabasalids, which are anaerobic flagellated protozoans. disease_ontology DOID:0050238 obsolete Parabasalia infectious disease true A parasitic protozoa infectious disease that involves infection caused by parabasalids, which are anaerobic flagellated protozoans. url:http://en.wikipedia.org/wiki/Parabasalid A parasitic protozoa infectious disease that involves infection caused by fornicates, which are unicellular flagellates with one or two karyomastigonts per cell. disease_ontology DOID:0050239 obsolete Fornicata infectious disease true A parasitic protozoa infectious disease that involves infection caused by fornicates, which are unicellular flagellates with one or two karyomastigonts per cell. url:http://tolweb.org/Fornicata/121182 A Parabasalia infectious disease that involves infection with anaerobic flagellate parasites belonging to the order Trichomonadida. They typically have four to six flagella at the cell's apical pole. disease_ontology DOID:0050240 obsolete Trichomonadida infectious disease true A Parabasalia infectious disease that involves infection with anaerobic flagellate parasites belonging to the order Trichomonadida. They typically have four to six flagella at the cell's apical pole. url:http://en.wikipedia.org/wiki/Trichomonad A Parabasalia infectious disease that involves infection with anaerobic flagellate parasites belonging to the order Tritrichomonadida, which are characterized by a single mastigont with four flagella, and both a comb-like structure and an infrakinetosomal body. disease_ontology DOID:0050241 obsolete Tritrichomonadida infectious disease true A Parabasalia infectious disease that involves infection with anaerobic flagellate parasites belonging to the order Tritrichomonadida, which are characterized by a single mastigont with four flagella, and both a comb-like structure and an infrakinetosomal body. url:http://www.ncbi.nlm.nih.gov/sites/entrez/20093080 A parasitic protozoa infectious disease that involves infection of the central nervous system caused by Naegleria fowleri. The symptoms include headache, nausea, rigidity of the neck muscles, vomiting, delirium, seizures and coma. GARD:9554 Naegleria fowleri infection disease_ontology DOID:0050242 primary amebic meningoencephalitis A parasitic protozoa infectious disease that involves infection of the central nervous system caused by Naegleria fowleri. The symptoms include headache, nausea, rigidity of the neck muscles, vomiting, delirium, seizures and coma. url:http://en.wikipedia.org/wiki/Primary_amoebic_meningoencephalitis url:http://www.dpd.cdc.gov/dpdx/HTML/FreeLivingAmebic.htm An Alveolata infectious disease that involves infection caused by the members of the phylum Apicomplexa, which are unicellular, spore forming parasites of animals and humans. disease_ontology DOID:0050243 obsolete Apicomplexa infectious disease true An Alveolata infectious disease that involves infection caused by the members of the phylum Apicomplexa, which are unicellular, spore forming parasites of animals and humans. url:http://en.wikipedia.org/wiki/Apicomplexa An Apicomplexa infectious disease that involves infection caused by the members of the class Coccidia, which are spore-forming, single-celled and obligate intracellular parasites of the intestinal tract of animals and humans. disease_ontology DOID:0050244 obsolete Coccidia infectious disease true An Apicomplexa infectious disease that involves infection caused by the members of the class Coccidia, which are spore-forming, single-celled and obligate intracellular parasites of the intestinal tract of animals and humans. url:http://en.wikipedia.org/wiki/Coccidia An Apicomplexa infectious disease that involves infection caused by the members of the class Aconoidasida. disease_ontology DOID:0050245 obsolete Aconoidasida infectious disease true An Apicomplexa infectious disease that involves infection caused by the members of the class Aconoidasida. url:http://en.wikipedia.org/wiki/Aconoidasida A parasitic protozoa infectious disease that results in infection of the brain caused by Acanthamoeba or Balamuthia mandrillaris. The symptoms include headaches, altered mental status, and focal neurologic deficit, which progresses over several weeks to death. GARD:12651 Acanthamoeba encephalitis Acanthamoeba granulomatous encephalitis Granulomatous Amebic Encephalitis due to Acanthamoeba granulomatous amoebic encephalitis disease_ontology DOID:0050246 granulomatous amebic encephalitis A parasitic protozoa infectious disease that results in infection of the brain caused by Acanthamoeba or Balamuthia mandrillaris. The symptoms include headaches, altered mental status, and focal neurologic deficit, which progresses over several weeks to death. url:http://www.dpd.cdc.gov/dpdx/HTML/FreeLivingAmebic.htm A parasitic infectious disease that involves infection caused by parasitic members of the taxon stramenopiles, in which the flagellate cells possess two different shaped flagella. This taxon contains both unicellular and multicellular organisms. disease_ontology DOID:0050247 obsolete parasitic stramenopiles infectious disease true A parasitic infectious disease that involves infection caused by parasitic members of the taxon stramenopiles, in which the flagellate cells possess two different shaped flagella. This taxon contains both unicellular and multicellular organisms. url:http://en.wikipedia.org/wiki/Stramenopiles A filarial elephantiasis that involves parasitic infection by the nematode Brugia timori, which inhabits the lymphatics. The symptoms include fever and chronic lymphedema. disease_ontology DOID:0050249 obsolete Brugia timori filariasis true A filarial elephantiasis that involves parasitic infection by the nematode Brugia timori, which inhabits the lymphatics. The symptoms include fever and chronic lymphedema. url:http://en.wikipedia.org/wiki/Brugia_timori A parasitic helminthiasis infectious disease that involves parasitic infection of the eyes by Philophthalmus species. External ocular philophthalmiasis manifests as follicular conjunctivitis and superficial keratitis. Sub-conjunctival ocular philophthalmiasis consists of a mild edema with minimal cellular reaction. disease_ontology DOID:0050250 philophthalmiasis A parasitic helminthiasis infectious disease that involves parasitic infection of the eyes by Philophthalmus species. External ocular philophthalmiasis manifests as follicular conjunctivitis and superficial keratitis. Sub-conjunctival ocular philophthalmiasis consists of a mild edema with minimal cellular reaction. url:http://www.dpd.cdc.gov/dpdx/HTML/Philophthalmiasis.htm A parasitic helminthiasis infectious disease that involves infection by metacestode larval stage (coenurus) of Taenia multiceps or Taenia serialis. Coenuri in the skin or subcutaneous tissue present as painless nodules, which manifest on the trunk, sclera, subconjuctiva, neck, shoulders, head and limbs. Coenuri in the central nervous system may cause headache, fever, vomiting, nerve palsies, jacksonian epilepsy, pachymeningitis, obstructive or communicating hydrocephalus, and intracranial arteritis with transient hemiparesis. Coenuri in the eye cause both intraocular and orbital infections. disease_ontology DOID:0050251 coenurosis A parasitic helminthiasis infectious disease that involves infection by metacestode larval stage (coenurus) of Taenia multiceps or Taenia serialis. Coenuri in the skin or subcutaneous tissue present as painless nodules, which manifest on the trunk, sclera, subconjuctiva, neck, shoulders, head and limbs. Coenuri in the central nervous system may cause headache, fever, vomiting, nerve palsies, jacksonian epilepsy, pachymeningitis, obstructive or communicating hydrocephalus, and intracranial arteritis with transient hemiparesis. Coenuri in the eye cause both intraocular and orbital infections. url:https://en.wikipedia.org/wiki/Coenurosis url:https://www.cdc.gov/dpdx/coenurosis/index.html A parasitic helminthiasis infectious disease that involves parasitic infection in dogs, cats and humans caused by cysticercoid larvae of Dipylidium caninum through ingestion of larvae contaminated flea, which results in diarrhea and restlessness. disease_ontology DOID:0050252 obsolete Dipylidium caninum infectious disease true A parasitic helminthiasis infectious disease that involves parasitic infection in dogs, cats and humans caused by cysticercoid larvae of Dipylidium caninum through ingestion of larvae contaminated flea, which results in diarrhea and restlessness. url:http://en.wikipedia.org/wiki/Dipylidium_caninum url:http://www.dpd.cdc.gov/dpdx/HTML/Dipylidium.htm A parasitic helminthiasis infectious disease that involves parasitic cestode infection caused by Mesocestoides lineatus resulting in nausea, diarrhea, abdominal discomfort and vomiting. disease_ontology DOID:0050253 mesocestoidiasis A parasitic helminthiasis infectious disease that involves parasitic cestode infection caused by Mesocestoides lineatus resulting in nausea, diarrhea, abdominal discomfort and vomiting. url:http://www.dpd.cdc.gov/dpdx/HTML/Mesocestoidiasis.htm A parasitic helminthiasis infectious disease that involves infection of the intestine caused by thorny-headed worms Macracanthorhynchus or Moniliformis moniliformis. The infection has_symptom abdominal pain, has_symptom distension, has_symptom fever, has_symptom decreased appetite, has_symptom nausea, has_symptom vomiting, has_symptom weight loss, has_symptom diarrhea, and has_symptom constipation or has_symptom bloody stools. disease_ontology DOID:0050254 acanthocephaliasis A parasitic helminthiasis infectious disease that involves infection of the intestine caused by thorny-headed worms Macracanthorhynchus or Moniliformis moniliformis. The infection has_symptom abdominal pain, has_symptom distension, has_symptom fever, has_symptom decreased appetite, has_symptom nausea, has_symptom vomiting, has_symptom weight loss, has_symptom diarrhea, and has_symptom constipation or has_symptom bloody stools. url:https://www.cdc.gov/dpdx/acanthocephaliasis/index.html A parasitic helminthiasis infectious disease that involves infection of the small intestine in humans, cats, dogs and foxes by the nematode Uncinaria stenocephala. The symptoms include diarrhea and hypoproteinemia in heavier infections. disease_ontology DOID:0050255 obsolete Uncinaria stenocephala infectious disease true A parasitic helminthiasis infectious disease that involves infection of the small intestine in humans, cats, dogs and foxes by the nematode Uncinaria stenocephala. The symptoms include diarrhea and hypoproteinemia in heavier infections. url:http://en.wikipedia.org/wiki/Uncinaria_stenocephala A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis. GARD:683 MESH:C536369 disease_ontology DOID:0050256 angiostrongyliasis A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine, central nervous system and eyes by Angiostrongylus cantonensis or Angiostrongylus costaricensis. url:https://en.wikipedia.org/wiki/Angiostrongyliasis An angiostrongyliasis that involves infection of the brain by the larvae of Angiostrongylus cantonensis causing eosinophilic meningitis. The symptoms include severe headache, nausea, vomiting, neck stiffness, seizures, and neurologic abnormalities. Ocular invasion by the larvae can occur. disease_ontology DOID:0050257 obsolete Angiostrongylus cantonensis infectious disease true An angiostrongyliasis that involves infection of the intestine by Angiostrongylus costaricensis, which is characterized by the formation of granulomas with heavy eosinophilic infiltration in the abdominal cavity. disease_ontology DOID:0050258 obsolete Angiostrongylus costaricensis infectious disease true An angiostrongyliasis that involves infection of the intestine by Angiostrongylus costaricensis, which is characterized by the formation of granulomas with heavy eosinophilic infiltration in the abdominal cavity. url:http://www.ncbi.nlm.nih.gov/sites/entrez/5527668 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine caused by the larvae of Baylisascaris procyonis, which can invade the spinal cord, brain, and eye of humans, resulting in permanent neurologic damage, blindness, or death. disease_ontology DOID:0050259 baylisascariasis A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine caused by the larvae of Baylisascaris procyonis, which can invade the spinal cord, brain, and eye of humans, resulting in permanent neurologic damage, blindness, or death. url:https://en.wikipedia.org/wiki/Baylisascaris A parasitic helminthiasis infectious disease that involves parasitic infection by the nematode Dioctophyme renale in humans after eating undercooked food. The larvae are found in the subcutaneous nodules and kidneys. disease_ontology DOID:0050260 dioctophymiasis A parasitic helminthiasis infectious disease that involves parasitic infection by the nematode Dioctophyme renale in humans after eating undercooked food. The larvae are found in the subcutaneous nodules and kidneys. url:http://www.dpd.cdc.gov/dpdx/HTML/Dioctophymiasis.htm A parasitic helminthiasis infectious diseasea that involves infection of the eyes in humans by nematode Thelazia callipaeda causing varying degrees of inflammation and lacrimation. In heavier infections, photophobia, edema, conjunctivitis, and blindness occurs. disease_ontology DOID:0050261 thelaziasis A parasitic helminthiasis infectious diseasea that involves infection of the eyes in humans by nematode Thelazia callipaeda causing varying degrees of inflammation and lacrimation. In heavier infections, photophobia, edema, conjunctivitis, and blindness occurs. url:http://www.dpd.cdc.gov/dpdx/HTML/Thelaziasis.htm A parasitic helminthiasis infectious disease that involves infection caused by parasitic worms, which are bilaterian, unsegmented, soft-bodied invertebrate animals with no body cavity. disease_ontology DOID:0050262 obsolete Acoelomata infectious disease true A parasitic helminthiasis infectious disease that involves infection caused by parasitic worms, which are bilaterian, unsegmented, soft-bodied invertebrate animals with no body cavity. url:http://en.wikipedia.org/wiki/Flatworm A parasitic helminthiasis infectious disease that involves infection caused by parasitic invertebrates, which have a pseudocoel. Tissue derived from mesoderm only partly lines the fluid filled body cavity of these animals. disease_ontology DOID:0050263 obsolete Pseudocoelomata infectious disease true A parasitic helminthiasis infectious disease that involves infection caused by parasitic invertebrates, which have a pseudocoel. Tissue derived from mesoderm only partly lines the fluid filled body cavity of these animals. url:http://en.wikipedia.org/wiki/Body_cavity A Pseudocoelomata infectious disease that involves infection by parasitic worms known as thorny-headed worms, characterized by the presence of an evertable proboscis, armed with spines, which is used to pierce and hold the gut wall of the host. disease_ontology DOID:0050264 obsolete Acanthocephala infectious disease true A Pseudocoelomata infectious disease that involves infection by parasitic worms known as thorny-headed worms, characterized by the presence of an evertable proboscis, armed with spines, which is used to pierce and hold the gut wall of the host. url:http://en.wikipedia.org/wiki/Acanthocephala disease_ontology DOID:0050265 obsolete tick paralysis true A parasitic ectoparasitic infectious disease that is an inflammatory skin disease caused by the parasitic infestation of the female chigoe flea, Tunga penetrans in animals and humans. The symptoms include skin inflammation, severe pain, itching, and a lesion at the site of infection that is characterized by a black dot at the center of a swollen red lesion, surrounded a white halo. GARD:393 MESH:D058285 disease_ontology DOID:0050266 tungiasis A parasitic ectoparasitic infectious disease that is an inflammatory skin disease caused by the parasitic infestation of the female chigoe flea, Tunga penetrans in animals and humans. The symptoms include skin inflammation, severe pain, itching, and a lesion at the site of infection that is characterized by a black dot at the center of a swollen red lesion, surrounded a white halo. url:http://en.wikipedia.org/wiki/Tungiasis url:http://www.dpd.cdc.gov/dpdx/HTML/Tungiasis.htm disease_ontology DOID:0050267 obsolete Ancylostoma caninum ancylostomiasis true A myiasis that involves parasitic infestation of Oestrus ovis larvae in the eye causing severe irritation, edema, and pain. disease_ontology DOID:0050268 ophthalmomyiasis A myiasis that involves parasitic infestation of Oestrus ovis larvae in the eye causing severe irritation, edema, and pain. url:http://en.wikipedia.org/wiki/Myiasis url:http://www.dpd.cdc.gov/dpdx/HTML/Myiasis.htm A trichomoniasis that involves infection of the urogenital tract, has_material_basis_in Trichomonas vaginalis, which is transmitted through sexual contact. Symptoms include inflammation of the cervix, urethra and vagina which produce an itching or burning sensation, and yellow-green, itchy, frothy foul-smelling vaginal discharge. ICD10CM:A59.00 MESH:D014247 NCI:C35083 urogenital trichomonas disease_ontology DOID:0050269 Trichomonas vaginalis trichomoniasis A trichomoniasis that involves infection of the urogenital tract, has_material_basis_in Trichomonas vaginalis, which is transmitted through sexual contact. Symptoms include inflammation of the cervix, urethra and vagina which produce an itching or burning sensation, and yellow-green, itchy, frothy foul-smelling vaginal discharge. url:http://en.wikipedia.org/wiki/Trichomoniasis A trichomoniasis that is caused by a singled-celled protozoan parasite Trichomonas tenax, which is transmitted through oral droplets, by kissing, or on fomites such as eating utensils. Trichomonas tenax causes periodonitis and bronchopulmonary trichomoniasis by aspiration from the oropharynx. disease_ontology DOID:0050270 Trichomonas tenax trichomoniasis A trichomoniasis that is caused by a singled-celled protozoan parasite Trichomonas tenax, which is transmitted through oral droplets, by kissing, or on fomites such as eating utensils. Trichomonas tenax causes periodonitis and bronchopulmonary trichomoniasis by aspiration from the oropharynx. url:http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mmed&part=A4222 url:http://www.ncbi.nlm.nih.gov/sites/entrez/20427914 A cutaneous mycosis that results_in fungal infection located_in skin, located_in hair and located_in nail, has_material_basis_in Ascomycota phylum members. disease_ontology DOID:0050271 obsolete cutaneous ascomycota mycosis true A cutaneous mycosis that results_in fungal infection located_in skin, located_in hair and located_in nail, has_material_basis_in Ascomycota phylum members. url:http://en.wikipedia.org/wiki/Ascomycota A cutaneous mycosis that results_in fungal infection located_in skin, located_in hair and located_in nail, has_material_basis_in Basidiomycota phylum members. disease_ontology DOID:0050272 obsolete cutaneous basidiomycota mycosis true A cutaneous mycosis that results_in fungal infection located_in skin, located_in hair and located_in nail, has_material_basis_in Basidiomycota phylum members. url:http://en.wikipedia.org/wiki/Basidiomycota A dermatomycosis that results_in fungal infection located_in nail, has_material_basis_in Neoscytalidium dimidiatum and has_symptom rough nail, and has_symptom crumbly nail which can separate from the nail bed. disease_ontology DOID:0050273 obsolete Neoscytalidium dimidiatum infectious disease true A dermatomycosis that results_in fungal infection located_in nail, has_material_basis_in Neoscytalidium dimidiatum and has_symptom rough nail, and has_symptom crumbly nail which can separate from the nail bed. url:http://www.doctorfungus.org/mycoses/human/other/skin_index.htm#Onychomycosis url:http://www.ncbi.nlm.nih.gov/sites/entrez/17641983 An opportunistic mycosis that has_material_basis_in Scopulariopsis, which results_in a systemic infection in immunocompromised individuals. disease_ontology DOID:0050274 obsolete Scopulariopsis infectious disease true An opportunistic mycosis that has_material_basis_in Scopulariopsis, which results_in a systemic infection in immunocompromised individuals. url:http://www.doctorfungus.org/thefungi/scopulariopsis.htm A dermatomycosis that results_in fungal infection located_in nail, has_material_basis_in Ascomycota fungi which are not dermatophytes and has_symptom opaque nail, has_symptom yellow-brown nail, has_symptom crumbly nail that can separate from the nail bed. disease_ontology DOID:0050275 obsolete onychomycosis true A dermatomycosis that results_in fungal infection located_in nail, has_material_basis_in Ascomycota fungi which are not dermatophytes and has_symptom opaque nail, has_symptom yellow-brown nail, has_symptom crumbly nail that can separate from the nail bed. url:http://en.wikipedia.org/wiki/Onychomycosis url:http://www.doctorfungus.org/mycoses/human/other/skin_index.htm#Onychomycosis A subcutaneous mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, has_material_basis_in Ascomycota phylum members. disease_ontology DOID:0050276 obsolete subcutaneous ascomycota mycosis true A subcutaneous mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, has_material_basis_in Ascomycota phylum members. url:http://en.wikipedia.org/wiki/Ascomycota url:http://en.wikipedia.org/wiki/Mycosis A subcutaneous mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, has_material_basis_in Fungi incertae sedis taxon members. disease_ontology DOID:0050277 obsolete subcutaneous fungi incertae sedis mycosis true A subcutaneous mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue, has_material_basis_in Fungi incertae sedis taxon members. url:http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=112252&lvl=3&lin=f&keep=1&srchmode=1&unlock A subcutaneous mycosis that involves a chronic inflammatory or granulomatous fungal infection of the subcutaneous tissue of the limbs, chest, back or buttocks caused by Basidiobolus ranarum. Lesions appear as subcutaneous nodules which develop into massive, firm, indurated, painless swellings which are freely movable over the underlying muscle, but are attached to the skin which may become hyperpigmented but not ulcerated. disease_ontology DOID:0050278 basidiobolomycosis A subcutaneous mycosis that involves a chronic inflammatory or granulomatous fungal infection of the subcutaneous tissue of the limbs, chest, back or buttocks caused by Basidiobolus ranarum. Lesions appear as subcutaneous nodules which develop into massive, firm, indurated, painless swellings which are freely movable over the underlying muscle, but are attached to the skin which may become hyperpigmented but not ulcerated. url:https://en.wikipedia.org/wiki/Basidiobolomycosis An subcutaneous mycosis that is a chronic inflammatory or granulomatous fungal infection caused by Conidiobolus species, which is restricted to the nasal submucosa and characterized by polyps or palpable restricted subcutaneous masses. Symptoms include nasal obstruction, drainage and sinus pain. Subcutaneous nodules develop in the nasal and perinasal regions. disease_ontology DOID:0050279 conidiobolomycosis An subcutaneous mycosis that is a chronic inflammatory or granulomatous fungal infection caused by Conidiobolus species, which is restricted to the nasal submucosa and characterized by polyps or palpable restricted subcutaneous masses. Symptoms include nasal obstruction, drainage and sinus pain. Subcutaneous nodules develop in the nasal and perinasal regions. url:https://en.wikipedia.org/wiki/Conidiobolomycosis A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Ascomycota phylum members. disease_ontology DOID:0050280 obsolete superficial ascomycota mycosis true A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Ascomycota phylum members. url:http://en.wikipedia.org/wiki/Ascomycota A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Basidiomycota phylum members. disease_ontology DOID:0050281 obsolete superficial basidiomycota mycosis true A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Basidiomycota phylum members. url:http://en.wikipedia.org/wiki/Basidiomycota A primary systemic mycosis that results_in fungal infection located_in human body, has_material_basis_in Ascomycota phylum members. disease_ontology DOID:0050282 obsolete primary systemic ascomycota mycosis true A primary systemic mycosis that results_in fungal infection located_in human body, has_material_basis_in Ascomycota phylum members. url:http://en.wikipedia.org/wiki/Ascomycota url:http://mycology.adelaide.edu.au/Mycoses/Opportunistic/ A primary systemic mycosis that results_in systemic fungal infection in animals and humans, has_material_basis_in Stachybotrys chartarum, transmitted_by airborne spores and transmitted_by vehicle-borne ingestion and the fungus produces trichothecene mycotoxins including satratoxins causing pulmonary hemorrhage in infants. disease_ontology DOID:0050283 obsolete Stachybotrys infectious disease true A primary systemic mycosis that results_in systemic fungal infection in animals and humans, has_material_basis_in Stachybotrys chartarum, transmitted_by airborne spores and transmitted_by vehicle-borne ingestion and the fungus produces trichothecene mycotoxins including satratoxins causing pulmonary hemorrhage in infants. url:http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Stachybotrys.pdf url:http://www.doh.wa.gov/ehp/ts/iaq/mold-stachybotrys.pdf An opportunistic mycosis that involves infection of the body by fungi belonging to the phylum Ascomycota. disease_ontology DOID:0050284 obsolete opportunistic ascomycota mycosis true An opportunistic mycosis that involves infection of the body by fungi belonging to the phylum Ascomycota. url:http://en.wikipedia.org/wiki/Ascomycota url:http://mycology.adelaide.edu.au/Mycoses/Opportunistic/ An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Basidiomycota phylum members. disease_ontology DOID:0050285 obsolete opportunistic basidiomycota mycosis true An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Basidiomycota phylum members. url:http://en.wikipedia.org/wiki/Basidiomycota url:http://mycology.adelaide.edu.au/Mycoses/Opportunistic/ An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Fungi incertae sedis taxon members. disease_ontology DOID:0050286 obsolete opportunistic fungi incertae sedis mycosis true An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Fungi incertae sedis taxon members. url:http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=112252&lvl=3&lin=f&keep=1&srchmode=1&unlock An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Microsporidia phylum members. disease_ontology DOID:0050287 obsolete opportunistic microsporidia mycosis true An opportunistic mycosis that results_in fungal infection located_in human body, has_material_basis_in Microsporidia phylum members. url:http://en.wikipedia.org/wiki/Microsporidia url:http://mycology.adelaide.edu.au/Mycoses/Opportunistic/ An opportunistic mycosis that has_material_basis_in Penicillium marneffei, results_in systemic infection and has_symptom fever, has_symptom anemia, has_symptom weight loss, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom respiratory signs, and has_symptom skin lesions. disease_ontology DOID:0050288 penicilliosis An opportunistic mycosis that has_material_basis_in Penicillium marneffei, results_in systemic infection and has_symptom fever, has_symptom anemia, has_symptom weight loss, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom respiratory signs, and has_symptom skin lesions. url:http://www.ncbi.nlm.nih.gov/sites/entrez/16418525 An opportunistic mycosis that involves localized or hematogenously disseminated fungal infection by Fusarium solani or Fusarium oxysporum. Skin lesions are seen in neutropenic patients, and indolent cellulitis or soft-tissue necrosis occur in immunocompromised patients at the site of trauma. MESH:D060585 disease_ontology DOID:0050289 fusariosis An opportunistic mycosis that involves localized or hematogenously disseminated fungal infection by Fusarium solani or Fusarium oxysporum. Skin lesions are seen in neutropenic patients, and indolent cellulitis or soft-tissue necrosis occur in immunocompromised patients at the site of trauma. url:https://www.ncbi.nlm.nih.gov/pubmed/14748803 An opportunistic mycosis that results_in disseminated infection, has_material_basis_in Trichosporon and results_in_formation_of nontender erythematous nodules anywhere on the body. MESH:D060586 disease_ontology DOID:0050290 trichosporonosis An opportunistic mycosis that results_in disseminated infection, has_material_basis_in Trichosporon and results_in_formation_of nontender erythematous nodules anywhere on the body. url:https://en.wikipedia.org/wiki/Trichosporonosis A parasitic infectious disease that involves parasitic infection by the members of the class Ichthyosporea, which are parasites of fish and other animals. disease_ontology DOID:0050291 parasitic Ichthyosporea infectious disease A parasitic infectious disease that involves parasitic infection by the members of the class Ichthyosporea, which are parasites of fish and other animals. url:http://en.wikipedia.org/wiki/Mesomycetozoea A systemic mycosis that results_in infection located_in human body, has_material_basis_in Fungi, which can overcome the physiological and cellular defences of the normal human host. The primary deep pathogens usually gain access to the host via the respiratory tract. disease_ontology DOID:0050292 primary systemic mycosis A systemic mycosis that results_in infection located_in human body, has_material_basis_in Fungi, which can overcome the physiological and cellular defences of the normal human host. The primary deep pathogens usually gain access to the host via the respiratory tract. url:https://dermnetnz.org/topics/skin-manifestations-of-systemic-mycoses An opportunistic mycosis that results_in fungal infection located_in nail, has_material_basis_in Scopulariopsis brevicaulis and has_symptom rough nail, and has_symptom crumbly nail which can separate from the nail bed. disease_ontology DOID:0050293 obsolete Scopulariopsis brevicaulis infectious disease true An opportunistic mycosis that results_in fungal infection located_in nail, has_material_basis_in Scopulariopsis brevicaulis and has_symptom rough nail, and has_symptom crumbly nail which can separate from the nail bed. url:http://www.doctorfungus.org/thefungi/Scopulariopsis_brevicaulis.htm A dermatomycosis that results_in fungal infection located_in hand, foot and nail of toe by Scytalidium hyalinum, resulting_in_formation_of lesions and has_symptom keratotic plantar surface. disease_ontology DOID:0050294 obsolete Scytalidium hyalinum infectious disease true A dermatomycosis that results_in fungal infection located_in hand, foot and nail of toe by Scytalidium hyalinum, resulting_in_formation_of lesions and has_symptom keratotic plantar surface. url:http://archderm.ama-assn.org/cgi/reprint/127/7/1041.pdf url:http://www.ncbi.nlm.nih.gov/sites/entrez/444431 A primary systemic mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue through direct inoculation from wood splinters or hay, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which results_in_formation_of erythematous papulonodular lesions evolving into either smooth or verrucose painless nodules that may ulcerate and drain. plaque sporotrichosis disease_ontology DOID:0050295 obsolete cutaneous sporotrichosis true A primary systemic mycosis that results_in fungal infection located_in skin and located_in subcutaneous tissue through direct inoculation from wood splinters or hay, has_material_basis_in Sporothrix schenckii, a dimorphic fungus, which results_in_formation_of erythematous papulonodular lesions evolving into either smooth or verrucose painless nodules that may ulcerate and drain. url:http://mycology.adelaide.edu.au/Mycoses/Subcutaneous/Sporotrichosis/ url:http://www.doctorfungus.org/mycoses/human/sporo/sporotrichosis.htm A dsDNA virus infectious disease that results_in infection in pigs, has_material_basis_in Asfarviridae viruses, which are transmitted_by soft tick bite. disease_ontology DOID:0050296 obsolete Asfarviridae infectious disease true A dsDNA virus infectious disease that results_in infection in pigs, has_material_basis_in Asfarviridae viruses, which are transmitted_by soft tick bite. url:http://en.wikipedia.org/wiki/Asfarviridae disease_ontology DOID:0050297 obsolete primary Francisellaceae infectious disease true A viral infectious disease that results_in infection in cattle, dogs, horses, pigs, and humans, has_material_basis_in Adenoviridae viruses. DOID:3123 DOID:3124 Adenoviridae infectious disease disease_ontology DOID:0050298 obsolete adenovirus infectious disease true A viral infectious disease that results_in infection in cattle, dogs, horses, pigs, and humans, has_material_basis_in Adenoviridae viruses. url:http://en.wikipedia.org/wiki/Adenoviridae A viral infectious disease that results_in infection in animals and humans, has_material_basis_in Simplexvirus. disease_ontology DOID:0050299 obsolete Simplexvirus infectious disease true A viral infectious disease that results_in infection in animals and humans, has_material_basis_in Simplexvirus. url:http://en.wikipedia.org/wiki/Simplexvirus A (-)ssRNA virus infectious disease that results_in infection located_in liver in humans, has_material_basis_in Deltavirus. disease_ontology DOID:0050300 obsolete Deltavirus infectious disease true A (-)ssRNA virus infectious disease that results_in infection located_in liver in humans, has_material_basis_in Deltavirus. url:http://en.wikipedia.org/wiki/Deltavirus A dsDNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Polyomaviridae viruses. disease_ontology DOID:0050301 obsolete Polyomaviridae infectious disease true A dsDNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Polyomaviridae viruses. url:http://en.wikipedia.org/wiki/Papillomaviridae A viral infectious disease that results_in infection in animals and humans, has_material_basis_in Varicellovirus. disease_ontology DOID:0050302 obsolete Varicellovirus infectious disease true A viral infectious disease that results_in infection in animals and humans, has_material_basis_in Varicellovirus. url:http://en.wikipedia.org/wiki/Varicellovirus url:http://www.expasy.org/viralzone/all_by_species/179.html A Flaviviridae infectious disease that results_in infection, has_material_basis_in Hepacivirus, which is transmitted_by sexual contact, or transmitted_by blood transfusion. disease_ontology DOID:0050303 obsolete Hepacivirus infectious disease true A Flaviviridae infectious disease that results_in infection, has_material_basis_in Hepacivirus, which is transmitted_by sexual contact, or transmitted_by blood transfusion. url:http://www.cdc.gov/hepatitis/hcv/pdfs/hepcgeneralfactsheet.pdf url:http://www.expasy.org/viralzone/all_by_species/37.html A refractive error that is characterized by the significant difference in perceived sizes of an object between the two eyes. MESH:D000839 disease_ontology DOID:0050304 aniseikonia A refractive error that is characterized by the significant difference in perceived sizes of an object between the two eyes. url:https://en.wikipedia.org/wiki/Aniseikonia A Nidovirales infectious disease that results_in infection in animals, has_material_basis_in Arteriviridae viruses. disease_ontology DOID:0050305 obsolete Arteriviridae infectious disease true A Nidovirales infectious disease that results_in infection in animals, has_material_basis_in Arteriviridae viruses. url:http://www.expasy.org/viralzone/all_by_species/28.html disease_ontology DOID:0050306 OMIM mapping confirmed by DO. [SN]. obsolete familial abdominal aortic aneurysm true A Mononegavirales infectious disease that results_in infection in animals and humans, has_material_basis_in Bornaviridae viruses. disease_ontology DOID:0050307 obsolete Bornaviridae infectious disease true A Mononegavirales infectious disease that results_in infection in animals and humans, has_material_basis_in Bornaviridae viruses. url:http://en.wikipedia.org/wiki/Bornaviridae A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Alkhurma hemorrhagic fever virus, which is transmitted by Ornithodoros savignyi tick bite, transmitted by ingestion of unpasteurized camel milk, or transmitted by entry via skin wound. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom thrombocytopenia, and has symptom hemorrhagic fever. disease_ontology DOID:0050308 Alkhurma hemorrhagic fever A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Alkhurma hemorrhagic fever virus, which is transmitted by Ornithodoros savignyi tick bite, transmitted by ingestion of unpasteurized camel milk, or transmitted by entry via skin wound. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom thrombocytopenia, and has symptom hemorrhagic fever. url:http://en.wikipedia.org/wiki/Alkhurma_virus A viral infectious disease that results_in infection, has_material_basis_in Measles virus, which is transmitted_by droplet spread, or trasnmitted_by contact of oronasal secretions from an infected person. disease_ontology DOID:0050309 obsolete Measles virus infectious disease true A viral infectious disease that results_in infection, has_material_basis_in Measles virus, which is transmitted_by droplet spread, or trasnmitted_by contact of oronasal secretions from an infected person. url:http://en.wikipedia.org/wiki/Measles disease_ontology DOID:0050310 obsolete primary Listeriaceae infectious disease true disease_ontology DOID:0050311 obsolete primary Helicobacteraceae infectious disease true disease_ontology DOID:0050312 obsolete primary Campylobacteraceae infectious disease true disease_ontology DOID:0050313 obsolete primary Brucellaceae infectious disease true disease_ontology DOID:0050314 obsolete primary Erysipelotrichaceae infectious disease true disease_ontology DOID:0050315 obsolete commensal Clostridiaceae infectious disease true disease_ontology DOID:0050316 obsolete commensal Staphylococcaceae infectious disease true disease_ontology DOID:0050317 obsolete commensal Streptococcaceae infectious disease true disease_ontology DOID:0050318 obsolete primary Burkholderiaceae infectious disease true disease_ontology DOID:0050319 obsolete primary Legionellaceae infectious disease true disease_ontology DOID:0050320 obsolete commensal Alcaligenaceae infectious disease true disease_ontology DOID:0050321 obsolete opportunistic Pseudomonadaceae infectious disease true disease_ontology DOID:0050322 obsolete primary Vibrionaceae infectious disease true disease_ontology DOID:0050323 obsolete primary Coxiellaceae infectious disease true A disorder that has an available objective mechanical test (such as chemical tests or brain scans), and are diagnosed only by behavioral syndrome (such as those in the Diagnostic and Statistical Manual of Mental Disorders (DSM). disease_ontology DOID:0050324 obsolete physical disorder OBSOLETED TERM true A disorder that has an available objective mechanical test (such as chemical tests or brain scans), and are diagnosed only by behavioral syndrome (such as those in the Diagnostic and Statistical Manual of Mental Disorders (DSM). url:http://en.wikipedia.org/wiki/Physical_disorder A medical disorder that is an illness caused by abnormalities in genes or chromosomes. disease_ontology DOID:0050325 obsolete genetic disorder true A medical disorder that is an illness caused by abnormalities in genes or chromosomes. url:http://en.wikipedia.org/wiki/Genetic_disorder url:http://www.ornl.gov/sci/techresources/Human_Genome/medicine/assist.shtml Peripheral Dysostosis-Nasal Hypoplasia-Mental Retardation disease_ontology DOID:0050327 OMIM mapping confirmed by DO. [SN]. obsolete peripheral dysostosis true A hypothyroidism that is present at birth. DOID:11631 DOID:11632 GARD:1487 ICD10CM:E00.1 ICD10CM:E03.1 ICD9CM:243 MESH:D003409 MIM:PS275200 NCI:C26734 NCI:C98921 SNOMEDCT_US_2023_03_01:217710005 SNOMEDCT_US_2023_03_01:75065003 UMLS_CUI:C0010308 UMLS_CUI:C0342200 disease_ontology DOID:0050328 Xref MGI. OMIM mapping confirmed by DO. [SN]. congenital hypothyroidism A hypothyroidism that is present at birth. url:http://en.wikipedia.org/wiki/Congenital_hypothyroidism url:http://ghr.nlm.nih.gov/condition/congenital-hypothyroidism A disorder that is a psychological or behavioral pattern associated with distress or disability that occurs in an individual and is not a part of normal development or culture. disease_ontology DOID:0050329 obsolete mental disorder true A disorder that is a psychological or behavioral pattern associated with distress or disability that occurs in an individual and is not a part of normal development or culture. url:http://en.wikipedia.org/wiki/Classification_of_mental_disorders url:http://en.wikipedia.org/wiki/Mental_disorder A syndrome that has_material_basis_in heterozygous mutation in the tyrosine kinase domain of the FGFR2 gene on chromosome 10q26 and that is characterized by autosomal dominant inheritance of abnormalities affecting the lacrimal and salivary glands and ducts, ears, teeth and fingers and toes. MIM:149730 LEVY-HOLLISTER SYNDROME Lacrimo-auriculo-dento-digital syndrome 1 disease_ontology DOID:0050331 OMIM mapping confirmed by DO. [SN]. lacrimoauriculodentodigital syndrome 1 A syndrome that has_material_basis_in heterozygous mutation in the tyrosine kinase domain of the FGFR2 gene on chromosome 10q26 and that is characterized by autosomal dominant inheritance of abnormalities affecting the lacrimal and salivary glands and ducts, ears, teeth and fingers and toes. url:http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=LADD%20Syndrome A vestibular disease that is characterized by progressive hearing loss resulting from congenital enlargement of the vestibular aqueducts. GARD:8651 disease_ontology DOID:0050332 OMIM mapping confirmed by DO. [SN]. enlarged vestibular aqueduct A vestibular disease that is characterized by progressive hearing loss resulting from congenital enlargement of the vestibular aqueducts. url:https://en.wikipedia.org/wiki/Enlarged_vestibular_aqueduct disease_ontology DOID:0050333 obsolete congenital anosmia true PHENYLTHIOCARBAMIDE TASTING, INCLUDED PROPYLTHIOURACIL TASTING, INCLUDED disease_ontology DOID:0050334 obsolete thiourea tasting true A retinal disease characterized by the slower than usual adaptation of the eyes to changing light conditions. GARD:12299 MESH:C564243 MIM:PS608415 ORDO:75374 SNOMEDCT_US_2023_03_01:711163009 UMLS_CUI:C1842073 prolonged electroretinal response suppression disease_ontology DOID:0050335 bradyopsia A retinal disease characterized by the slower than usual adaptation of the eyes to changing light conditions. url:https://medlineplus.gov/genetics/condition/bradyopsia/ url:https://www.ncbi.nlm.nih.gov/pubmed/17826834 A phosphorus metabolism disease that is characterized by hypophosphatemia and the symptoms of osteomalacia including bone pain, skeletal deformities and osteoarthritis. MESH:D017674 disease_ontology DOID:0050336 hypophosphatemia A phosphorus metabolism disease that is characterized by hypophosphatemia and the symptoms of osteomalacia including bone pain, skeletal deformities and osteoarthritis. url:https://en.wikipedia.org/wiki/Hypophosphatemia disease_ontology DOID:0050337 obsolete Burkholderia cepacia infectious disease true A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread. disease_ontology DOID:0050338 primary bacterial infectious disease A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread. url:http://en.wikipedia.org/wiki/Infectious_disease A bacterial infectious disease that results_in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder. disease_ontology DOID:0050339 commensal bacterial infectious disease A bacterial infectious disease that results_in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder. url:https://www.microbiologyinpictures.com/introduction.html url:https://www.ncbi.nlm.nih.gov/pubmed/24727150 A bacterial infectious disease that results_in infection by bacteria in individuals whose host defense mechanisms have been compromised. disease_ontology DOID:0050340 opportunistic bacterial infectious disease A bacterial infectious disease that results_in infection by bacteria in individuals whose host defense mechanisms have been compromised. url:http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mmed&part=A545 disease_ontology DOID:0050341 obsolete opportunistic Actinomycetales infectious disease true A commensal bacterial infectious disease that results_in infection, has_material_basis_in Actinomycetales bacteria, which are part of the normal human flora. disease_ontology DOID:0050342 obsolete commensal Actinomycetales infectious disease true A commensal bacterial infectious disease that results_in infection, has_material_basis_in Actinomycetales bacteria, which are part of the normal human flora. url:http://www.sovegastro.com/pdf/ACTINOMICOSIS%20ABDOMINAL.pdf disease_ontology DOID:0050343 obsolete Gardnerella vaginalis vaginosis true disease_ontology DOID:0050344 obsolete commensal Bifidobacteriaceae infectious disease true disease_ontology DOID:0050345 obsolete primary Thermomonosporaceae infectious disease true disease_ontology DOID:0050346 obsolete primary Corynebacteriaceae infectious disease true disease_ontology DOID:0050347 obsolete primary Mycobacteriaceae infectious disease true disease_ontology DOID:0050348 obsolete primary Streptomycetaceae infectious disease true disease_ontology DOID:0050349 obsolete opportunistic Nocardiaceae infectious disease true disease_ontology DOID:0050350 obsolete primary Clostridiaceae infectious disease true disease_ontology DOID:0050351 obsolete primary Clostridium infectious disease true A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F), which are transmitted by ingestion of food contaminated with preformed toxins, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F. The infection has symptom blurred vision, has symptom diplopia, has symptom dysarthria, has symptom dysphonia, has symptom dysphagia and has symptom descending muscle paralysis. disease_ontology DOID:0050352 foodborne botulism A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F), which are transmitted by ingestion of food contaminated with preformed toxins, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F. The infection has symptom blurred vision, has symptom diplopia, has symptom dysarthria, has symptom dysphonia, has symptom dysphagia and has symptom descending muscle paralysis. url:https://www.southernnevadahealthdistrict.org/Health-Topics/foodborne-botulism/ A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F), has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F, which are transmitted by contact of spores with the open wounds, which then reproduce in an anaerobic environment to produce toxins. disease_ontology DOID:0050353 wound botulism A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F), has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F, which are transmitted by contact of spores with the open wounds, which then reproduce in an anaerobic environment to produce toxins. url:http://www.who.int/mediacentre/factsheets/fs270/en/ A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA or B) in infants, has_material_basis_in Clostridium botulinum A or has_material_basis_in Clostridium botulinum B, which are transmitted_by ingestion of bacterial spores, which then grow in the intestine and release toxins. The infection has_symptom constipation, has_symptom lethargy, has_symptom difficulty feeding, has_symptom swallowing, has_symptom ptosis, has_symptom loss of head control, and has_symptom muscle weakness. disease_ontology DOID:0050354 infant botulism A botulism that involves intoxication caused by botulinum neurotoxins (BoNTA or B) in infants, has_material_basis_in Clostridium botulinum A or has_material_basis_in Clostridium botulinum B, which are transmitted_by ingestion of bacterial spores, which then grow in the intestine and release toxins. The infection has_symptom constipation, has_symptom lethargy, has_symptom difficulty feeding, has_symptom swallowing, has_symptom ptosis, has_symptom loss of head control, and has_symptom muscle weakness. url:https://www.aafp.org/afp/2002/0401/p1388.html disease_ontology DOID:0050355 obsolete opportunistic Burkholderiaceae infectious disease true disease_ontology DOID:0050357 obsolete Burkholderia cenocepacia infectious disease true disease_ontology DOID:0050358 obsolete commensal Chlamydiaceae infectious disease true disease_ontology DOID:0050359 obsolete Bilophila wadsworthia necrotizing fasciitis true disease_ontology DOID:0050360 obsolete commensal Enterobacteriaceae infectious disease true disease_ontology DOID:0050361 obsolete opportunistic Enterobacteriaceae infectious disease true disease_ontology DOID:0050362 obsolete Elizabethkingia meningoseptica infectious disease true disease_ontology DOID:0050363 obsolete Capnocytophaga canimorsus infectious disease true disease_ontology DOID:0050364 obsolete opportunistic Flavobacteriaceae infectious disease true disease_ontology DOID:0050365 obsolete Chryseobacterium indologenes infectious disease true disease_ontology DOID:0050366 obsolete Empedobacter brevis endophthalmitis true disease_ontology DOID:0050367 obsolete Myroides odoratus necrotizing fasciitis true disease_ontology DOID:0050368 obsolete commensal Fusobacteriaceae infectious disease true disease_ontology DOID:0050369 obsolete primary Mycoplasmataceae infectious disease true disease_ontology DOID:0050370 obsolete commensal Neisseriaceae infectious disease true disease_ontology DOID:0050371 obsolete commensal Pasteurellaceae infectious disease true disease_ontology DOID:0050372 obsolete commensal Haemophilus infectious disease true disease_ontology DOID:0050373 obsolete Leptospiraceae infectious disease true disease_ontology DOID:0050374 obsolete Spirochaetaceae infectious disease true disease_ontology DOID:0050375 obsolete primary Spirillaceae infectious disease true disease_ontology DOID:0050376 obsolete anaplasmosis true DOID:0050356 disease_ontology DOID:0050377 obsolete Burkholderia cepacia complex infectious disease true disease_ontology DOID:0050378 obsolete opportunistic Campylobacteraceae infectious disease true disease_ontology DOID:0050379 obsolete Campylobacter fetus infectious disease true disease_ontology DOID:0050380 obsolete Campylobacter coli infectious disease true disease_ontology DOID:0050381 obsolete Chlamydia trachomatis epididymitis true A tularemia that results_in swelling of regional lymph glands. disease_ontology DOID:0050382 glandular tularemia A tularemia that results_in swelling of regional lymph glands. url:http://www.cdc.gov/tularemia/signssymptoms/ A tularemia that results_in bacteremia and has_symptom fever, has_symptom chills, has_symptom myalgia, has_symptom malaise, and has_symptom weight loss. disease_ontology DOID:0050383 typhoidal tularemia A tularemia that results_in bacteremia and has_symptom fever, has_symptom chills, has_symptom myalgia, has_symptom malaise, and has_symptom weight loss. url:https://www.ncbi.nlm.nih.gov/pubmed/29635071 disease_ontology DOID:0050384 obsolete commensal Helicobacteraceae infectious disease true disease_ontology DOID:0050385 obsolete commensal Helicobacter infectious disease true disease_ontology DOID:0050386 obsolete Acinetobacter baumannii pneumonia true A hereditary renal cell carcinoma that has_material_basis_in a loss of 3p13-pter sequences. MIM:144700 disease_ontology DOID:0050387 OMIM mapping confirmed by DO. [SN]. nonpapillary renal cell carcinoma A hereditary renal cell carcinoma that has_material_basis_in a loss of 3p13-pter sequences. url:https://www.ncbi.nlm.nih.gov/pubmed/2921777 url:https://www.ncbi.nlm.nih.gov/pubmed/8415591 disease_ontology DOID:0050388 obsolete Bacteroides fragilis peritonitis true disease_ontology DOID:0050389 obsolete Capnocytophaga canimorsus meningitis true disease_ontology DOID:0050390 obsolete Capnocytophaga canimorsus endocarditis true disease_ontology DOID:0050391 obsolete Elizabethkingia meningoseptica meningitis true disease_ontology DOID:0050392 obsolete streptococcal necrotizing fasciitis true disease_ontology DOID:0050393 obsolete Chryseobacterium indologenes pneumonia true disease_ontology DOID:0050394 obsolete nocardial pneumonia true disease_ontology DOID:0050395 obsolete nocardial cellulitis true disease_ontology DOID:0050396 obsolete nocardial keratitis true disease_ontology DOID:0050397 obsolete cerebral Bilophila wadsworthia infectious disease true A bartonellosis that results_in infection located_in endothelial cells or located_in red blood cells, has_material_basis_in Bartonella bacilliformis, which is transmitted_by sandflies of genus Lutzomyia. The infection has acute and chronic phases. The acute phase is characterized by severe hemolytic anemia and transient immunosuppression. The chronic phase is characterized by verruga peruana lesions which may ulcerate and bleed. Carrion disease Oroya fever disease_ontology DOID:0050398 Carrion's disease A bartonellosis that results_in infection located_in endothelial cells or located_in red blood cells, has_material_basis_in Bartonella bacilliformis, which is transmitted_by sandflies of genus Lutzomyia. The infection has acute and chronic phases. The acute phase is characterized by severe hemolytic anemia and transient immunosuppression. The chronic phase is characterized by verruga peruana lesions which may ulcerate and bleed. url:http://en.wikipedia.org/wiki/Carrion%27s_disease disease_ontology DOID:0050399 obsolete Bordetella pertussis whooping cough true disease_ontology DOID:0050400 obsolete Pseudomonas urinary tract infectious disease true disease_ontology DOID:0050401 obsolete Pseudomonas endocarditis true disease_ontology DOID:0050402 obsolete Pseudomonas keratitis true disease_ontology DOID:0050403 obsolete commensal Mycoplasmatales infectious disease true disease_ontology DOID:0050404 obsolete commensal Mycoplasmataceae infectious disease true disease_ontology DOID:0050405 obsolete Mycoplasma genitalium urethritis true disease_ontology DOID:0050406 obsolete Yersinia pseudotuberculosis mesenteric lymphadenitis true disease_ontology DOID:0050407 obsolete commensal Mycoplasma infectious disease true disease_ontology DOID:0050408 obsolete Staphylococcus aureus ecthyma true disease_ontology DOID:0050409 obsolete Streptococcus pyogenes ecthyma true disease_ontology DOID:0050410 obsolete streptococcal erysipelas true disease_ontology DOID:0050411 obsolete Staphylococcus aureus erysipelas true disease_ontology DOID:0050412 obsolete Streptococcus impetigo true disease_ontology DOID:0050413 obsolete Staphylococcus aureus impetigo true disease_ontology DOID:0050414 obsolete Streptococcus lymphangitis true disease_ontology DOID:0050415 obsolete Staphylococcus aureus lymphangitis true disease_ontology DOID:0050416 obsolete Streptococcus agalactiae meningitis true Streptococcus dysgalactiae subsp. equisimilis meningitis disease_ontology DOID:0050417 obsolete Streptococcus equisimilis meningitis true Streptococcus equi subsp. zooepidemicus meningitis disease_ontology DOID:0050418 obsolete Streptococcus zooepidemicus meningitis true A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency. MESH:C572568 MIM:610984 C3 INACTIVATOR DEFICIENCY COMPLEMENT COMPONENT 3 INACTIVATOR DEFICIENCY disease_ontology DOID:0050419 OMIM mapping confirmed by DO. [SN]. complement factor I deficiency A complement deficiency that is characterized by recurrent pyogenic bacterial infections that is the result of complement component 3 deficiency. url:https://www.omim.org/entry/610984 disease_ontology DOID:0050420 obsolete primary Streptococcaceae infectious disease true disease_ontology DOID:0050421 obsolete primary streptococcal infectious disease true disease_ontology DOID:0050422 obsolete Yersinia pseudotuberculosis gastroenteritis true enteroaggregative E.coli infection disease_ontology DOID:0050423 obsolete enteroaggregative Escherichia coli infectious disease true An intestinal disease that has_material_basis_in mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer. GARD:6408 MESH:D011125 MIM:PS175100 NCI:C3339 ORDO:733 SNOMEDCT_US_2023_03_01:72900001 UMLS_CUI:C0032580 adenomatous polyposis of the colon disease_ontology DOID:0050424 OMIM mapping confirmed by DO. [SN]. familial adenomatous polyposis An intestinal disease that has_material_basis_in mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer. url:http://en.wikipedia.org/wiki/Familial_adenomatous_polyposis url:http://www.omim.org/entry/175100?search=adenomatous%20polyposis A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them. EFO:0004270 GARD:11926 ICD10CM:G25.81 ICD9CM:333.94 MESH:D012148 MIM:PS102300 NCI:C84501 SNOMEDCT_US_2023_03_01:32914008 UMLS_CUI:C0035258 WED Willis-Ekbom disease Wittmaack-Ekbom syndrome disease_ontology DOID:0050425 Xref MGI. restless legs syndrome A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them. url:http://en.wikipedia.org/wiki/Restless_legs_syndrome url:http://www.ninds.nih.gov/disorders/restless_legs/detail_restless_legs.htm WED A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection. EFO:0004276 GARD:7700 ICD10CM:L51.1 ICD9CM:695.13 MESH:D013262 NCI:C79484 SNOMEDCT_US_2023_03_01:73442001 UMLS_CUI:C0038325 disease_ontology DOID:0050426 Stevens-Johnson syndrome MESH:D013262 A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection. url:https://en.wikipedia.org/wiki/Stevens%E2%80%93Johnson_syndrome A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair. GARD:7910 ICD10CM:Q82.1 MESH:D014983 NCI:C3452 ORDO:910 SNOMEDCT_US_2023_03_01:44600005 UMLS_CUI:C0043346 disease_ontology DOID:0050427 OMIM mapping confirmed by DO. [SN]. xeroderma pigmentosum A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair. url:http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/339/viewAbstract A palmoplantar keratosis characterized by a well-demarcated, symmetric keratoderma located_in palms and located_in soles. MESH:C563422 UMLS_CUI:C1833030 NEPPK Thost-Unna Syndrome Unna-Thost Syndrome diffuse nonepidermolytic palmomplantar keratoderma tylosis disease_ontology DOID:0050428 nonepidermolytic palmoplantar keratoderma MESH:C563422 UMLS_CUI:C1833030 A palmoplantar keratosis characterized by a well-demarcated, symmetric keratoderma located_in palms and located_in soles. url:http://en.wikipedia.org/wiki/Palmoplantar_keratoderma NEPPK A pemphigus that is characterized by recurring blistering most commonly occurring in the folds of the skin, particularly the groin and axillary regions, and has_material_basis_in mutations in the ATP2C1 gene that result in loss of adhesion within the skin. Other sites of the body, such as the neck, perianal, and submammary regions, may likewise be affected. GARD:6559 ICD10CM:Q82.8 MESH:D016506 MIM:169600 NCI:C82865 SNOMEDCT_US_2023_03_01:79468000 UMLS_CUI:C0085106 BENIGN CHRONIC PEMPHIGUS Pemphigus, Benign Familial disease_ontology DOID:0050429 OMIM mapping confirmed by DO. [SN]. Hailey-Hailey disease A pemphigus that is characterized by recurring blistering most commonly occurring in the folds of the skin, particularly the groin and axillary regions, and has_material_basis_in mutations in the ATP2C1 gene that result in loss of adhesion within the skin. Other sites of the body, such as the neck, perianal, and submammary regions, may likewise be affected. url:https://rarediseases.org/rare-diseases/hailey-hailey-disease/ A multiple endocrine neoplasia characterized by medullary carcinoma of the thyroid, pheochromocytoma, hyperparathyroidism, and occasionally cutaneous lichen amyloidosis. ICD10CM:E31.22 ICD9CM:258.02 MESH:D018813 MIM:171400 NCI:C3226 ORDO:247698 SNOMEDCT_US_2023_03_01:721188000 UMLS_CUI:C0025268 MEN2A Sipple syndrome multiple endocrine neoplasia II disease_ontology DOID:0050430 OMIM mapping confirmed by DO. [SN]. multiple endocrine neoplasia type 2A A multiple endocrine neoplasia characterized by medullary carcinoma of the thyroid, pheochromocytoma, hyperparathyroidism, and occasionally cutaneous lichen amyloidosis. url:http://ghr.nlm.nih.gov/condition/multiple-endocrine-neoplasia url:http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/multiple_endocrine_neoplasia_men_syndromes/multiple_endocrine_neoplasia_type_2a_men_2a.html url:https://www.ncbi.nlm.nih.gov/pubmed/15965261 url:https://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1244/viewAbstract MEN2A An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle. MESH:D019571 MIM:PS107970 NCI:C84571 ORDO:217656 ORDO:247 SNOMEDCT_US_2023_03_01:281170005 UMLS_CUI:C0349788 ARVC ARVC cardiomyopathy ARVD arrhythmogenic right ventricular dysplasia arrhythmogenic right ventricular dysplasia/cardiomyopathy right ventricular ACM disease_ontology DOID:0050431 Xref MGI. OMIM mapping confirmed by DO. [SN]. arrhythmogenic right ventricular cardiomyopathy An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle. url:http://en.wikipedia.org/wiki/Arrhythmogenic_right_ventricular_dysplasia url:http://ghr.nlm.nih.gov/condition/arrhythmogenic-right-ventricular-cardiomyopathy url:http://my.clevelandclinic.org/services/heart/disorders/arvd url:http://www.hopkinsmedicine.org/heart_vascular_institute/clinical_services/centers_excellence/arvd/patient_resources/questions.html url:https://pubmed.ncbi.nlm.nih.gov/31637441/ ARVC ARVD An autism spectrum disorder that is characterized by significant difficulties in social interaction, along with restricted and repetitive patterns of behavior and interests. It differs from other autism spectrum disorders by its relative preservation of linguistic and cognitive development. GARD:5855 ICD10CM:F84.5 MESH:D020817 MIM:608631 MIM:608638 MIM:608781 MIM:609954 MIM:PS608638 NCI:C97159 ORDO:1162 SNOMEDCT_US_2023_03_01:154879004 UMLS_CUI:C0236792 disease_ontology DOID:0050432 Multiple OMIM IDs are susceptibility terms [LS] Asperger syndrome An autism spectrum disorder that is characterized by significant difficulties in social interaction, along with restricted and repetitive patterns of behavior and interests. It differs from other autism spectrum disorders by its relative preservation of linguistic and cognitive development. url:http://en.wikipedia.org/wiki/Asperger_syndrome url:http://www.neurodevnet.ca A prion disease that is characterized by insomnia, hallucinations, dementia and death, located_in the brain. GARD:6429 ICD10CM:A81.83 ICD9CM:046.72 MESH:D034062 MIM:600072 NCI:C84711 SNOMEDCT_US_2023_03_01:83157008 UMLS_CUI:C0206042 disease_ontology DOID:0050433 OMIM mapping confirmed by DO. [SN]. fatal familial insomnia A prion disease that is characterized by insomnia, hallucinations, dementia and death, located_in the brain. url:https://en.wikipedia.org/wiki/Fatal_familial_insomnia A long QT syndrome that has_material_basis_in autosomal dominant inheritance of a mutation in the KCNJ2 gene which disrupts the rhythm of the heart's lower chambers (ventricular arrhythmia) and results_in an unusually small lower jaw (micrognathia), low-set ears, and an abnormal curvature of the fingers called clinodactyly. GARD:9453 MESH:D050030 MIM:170390 NCI:C84559 ORDO:37553 SNOMEDCT_US_2023_03_01:422348008 UMLS_CUI:C1563715 ANDERSEN CARDIODYSRHYTHMIC PERIODIC PARALYSIS Andersen syndrome LQT7 Long QT syndrome 7 Potassium-Sensitive Cardiodysrhythmic Type disease_ontology DOID:0050434 OMIM mapping confirmed by DO. [SN]. Andersen-Tawil syndrome A long QT syndrome that has_material_basis_in autosomal dominant inheritance of a mutation in the KCNJ2 gene which disrupts the rhythm of the heart's lower chambers (ventricular arrhythmia) and results_in an unusually small lower jaw (micrognathia), low-set ears, and an abnormal curvature of the fingers called clinodactyly. url:http://en.wikipedia.org/wiki/Andersen%E2%80%93Tawil_syndrome url:http://en.wikipedia.org/wiki/Long_QT_syndrome LQT7 A syndrome that is characterized by global growth retardation of the muscle, liver, brain and eyes as well as constrictive pericarditis and has_material_basis_in mutations in the TRIM37 gene. GARD:95 MESH:D050336 MIM:253250 NCI:C84906 ORDO:2576 SNOMEDCT_US_2023_03_01:81604003 UMLS_CUI:C0524582 MUL Mulibrey growth disorder Muscle-Liver-Brain-Eye Nanism PERICARDIAL CONSTRICTION AND GROWTH FAILURE Perheentupa Syndrome disease_ontology DOID:0050436 OMIM mapping confirmed by DO. [SN]. mulibrey nanism A syndrome that is characterized by global growth retardation of the muscle, liver, brain and eyes as well as constrictive pericarditis and has_material_basis_in mutations in the TRIM37 gene. url:https://rarediseases.org/rare-diseases/mulibrey-nanism/ MUL A lysosomal storage disease that is characterized by cardiomyopathy, skeletal myopathy and intellectual disability and has_material_basis_in mutations in the LAMP2 gene. GARD:9730 MESH:D052120 MIM:300257 NCI:C84735 SNOMEDCT_US_2023_03_01:419097006 UMLS_CUI:C0878677 ANTOPOL DISEASE PSEUDOGLYCOGENOSIS II disease_ontology DOID:0050437 OMIM mapping confirmed by DO. [SN]. Danon disease A lysosomal storage disease that is characterized by cardiomyopathy, skeletal myopathy and intellectual disability and has_material_basis_in mutations in the LAMP2 gene. url:https://rarediseases.org/rare-diseases/danon-disease/ A syndrome that is characterized by gonadal dysgenesis, streak gonads, progressive focal segmental glomerulonephropathy and the development of urogenital cancers that is the result of mutation in the WT1 gene. GARD:2375 MESH:D052159 MIM:136680 NCI:C122805 SNOMEDCT_US_2023_03_01:445431000 UMLS_CUI:C0950122 disease_ontology DOID:0050438 OMIM mapping confirmed by DO. [SN]. Frasier syndrome A syndrome that is characterized by gonadal dysgenesis, streak gonads, progressive focal segmental glomerulonephropathy and the development of urogenital cancers that is the result of mutation in the WT1 gene. url:https://ghr.nlm.nih.gov/condition/frasier-syndrome A syndrome characterized by a combination of hearing loss and visual impairment. GARD:7843 MESH:D052245 MIM:PS276900 NCI:C85217 ORDO:886 SNOMEDCT_US_2023_03_01:57838006 UMLS_CUI:C0271097 disease_ontology DOID:0050439 Xref MGI. OMIM mapping confirmed by DO. [LS]. Usher syndrome A syndrome characterized by a combination of hearing loss and visual impairment. url:http://en.wikipedia.org/wiki/Usher_syndrome A partial lipodystrophy characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life. GARD:11962 MESH:D052496 MIM:PS151660 NCI:C165527 NCI:C84708 ORDO:98306 SNOMEDCT_US_2023_03_01:1197745002 SNOMEDCT_US_2023_03_01:49292002 SNOMEDCT_US_2023_03_01:715439000 SNOMEDCT_US_2023_03_01:725035001 UMLS_CUI:C0271694 UMLS_CUI:C1720859 UMLS_CUI:C1720860 UMLS_CUI:C1720861 Dunnigan Syndrome Koberling-Dunnigan Syndrome disease_ontology DOID:0050440 Xref MGI. OMIM mapping confirmed by DO. [SN]. familial partial lipodystrophy A partial lipodystrophy characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life. url:http://en.wikipedia.org/wiki/Familial_partial_lipodystrophy url:http://omim.org/entry/608600 A sphingolipidosis that is characterized by leukodystrophy, ichthyosis, skeletal abnormalities and shortened life expectancy and has_material_basis_in mutation in the SUMF1 gene that results in deficiency in multiple sulfatase enzymes. ICD10CM:E75.26 MESH:D052517 MIM:272200 NCI:C84908 SNOMEDCT_US_2023_03_01:254076009 SNOMEDCT_US_2023_03_01:54898003 UMLS_CUI:C0268263 UMLS_CUI:C1720864 Sulfatidosis, Juvenile, Austin Type multiple sulfatase deficiency disease disease_ontology DOID:0050441 OMIM mapping confirmed by DO. [SN]. mucosulfatidosis A sphingolipidosis that is characterized by leukodystrophy, ichthyosis, skeletal abnormalities and shortened life expectancy and has_material_basis_in mutation in the SUMF1 gene that results in deficiency in multiple sulfatase enzymes. url:https://ghr.nlm.nih.gov/condition/multiple-sulfatase-deficiency A peroxisomal disease that is characterized by neurological impairment, intellectual disability, hepatosplenomegaly and ichthyosis and results from the accumulation of very long chain fatty acids and phytanic acid, secondary to mutation in the PEX genes. ICD10CM:G60.1 MESH:D052919 NCI:C84789 SNOMEDCT_US_2023_03_01:238062008 UMLS_CUI:C0282527 infantile phytanic acid storage disease disease_ontology DOID:0050444 OMIM mapping confirmed by DO. [SN]. infantile Refsum disease A peroxisomal disease that is characterized by neurological impairment, intellectual disability, hepatosplenomegaly and ichthyosis and results from the accumulation of very long chain fatty acids and phytanic acid, secondary to mutation in the PEX genes. url:https://en.wikipedia.org/wiki/Infantile_Refsum_disease url:https://www.ncbi.nlm.nih.gov/books/NBK560618/ A rickets has_material_basis_in X-linked mutations in the PHEX gene that lead to increased circulating levels of FGF-23, a phosphate-regulating hormone (phosphatonin), that leads to reduced renal phosphate reabsorption and consequently abnormal bone mineralization. MESH:D053098 MIM:307800 NCI:C85234 UMLS_CUI:C0733682 UMLS_CUI:C1845168 UMLS_CUI:C3540852 Hypophosphatemia, Vitamin D-Resistant Rickets Vitamin D-Resistant Rickets, X-Linked X-linked hypophosphatemia hypophosphatemic rickets X-linked dominant disease_ontology DOID:0050445 OMIM mapping confirmed by DO. [SN]. X-linked dominant hypophosphatemic rickets A rickets has_material_basis_in X-linked mutations in the PHEX gene that lead to increased circulating levels of FGF-23, a phosphate-regulating hormone (phosphatonin), that leads to reduced renal phosphate reabsorption and consequently abnormal bone mineralization. url:http://en.wikipedia.org/wiki/X-linked_hypophosphatemia url:https://rarediseases.info.nih.gov/diseases/12943/x-linked-hypophosphatemia A skin disease characterized by a defect in the normal process of keratinization of the mucosa. GARD:8501 MESH:D053529 MIM:PS193900 NCI:C84760 ORDO:171723 SNOMEDCT_US_2023_03_01:85388002 UMLS_CUI:C1721005 hereditary mucosal leukokeratosis white sponge nevus of Cannon disease_ontology DOID:0050448 2023 nomenclature update to white sponge nevus. white sponge nevus A skin disease characterized by a defect in the normal process of keratinization of the mucosa. url:http://en.wikipedia.org/wiki/White_sponge_nevus url:https://pubmed.ncbi.nlm.nih.gov/29034652/ A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin. GARD:10753 MESH:D053549 MIM:PS167200 NCI:C84986 ORDO:2309 SNOMEDCT_US_2023_03_01:39427000 UMLS_CUI:C0265334 UMLS_CUI:C1706595 UMLS_CUI:C1721007 Jackson-Lawler Type Pachyonychia Congenita Jadassohn-Lewandowsky Syndrome PACHYONYCHIA CONGENITA, JADASSOHN-LEWANDOWSKY TYPE Pachyonychia Congenita Type 1 disease_ontology DOID:0050449 OMIM mapping confirmed by DO. [SN]. pachyonychia congenita A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin. url:https://ghr.nlm.nih.gov/condition/pachyonychia-congenita A renal tubular transport disease that is has_material_basis_in mutations in genes that produce proteins involved in the kidneys' reabsorption of salt (sodium chloride or NaCl) from urine back into the bloodstream, thus impairing the kidneys' ability to reabsorb salt, leading to the loss of excess salt in the urine (salt wasting). GARD:8547 MESH:D053579 MIM:263800 NCI:C84730 SNOMEDCT_US_2023_03_01:3188003 UMLS_CUI:C0268450 HYPOMAGNESEMIA-HYPOKALEMIA, PRIMARY RENOTUBULAR, WITH HYPOCALCIURIA disease_ontology DOID:0050450 OMIM mapping confirmed by DO. [SN]. Gitelman syndrome A renal tubular transport disease that is has_material_basis_in mutations in genes that produce proteins involved in the kidneys' reabsorption of salt (sodium chloride or NaCl) from urine back into the bloodstream, thus impairing the kidneys' ability to reabsorb salt, leading to the loss of excess salt in the urine (salt wasting). url:https://ghr.nlm.nih.gov/condition/gitelman-syndrome A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. GARD:1030 ICD10CM:I49.8 MESH:D053840 MIM:PS601144 NCI:C142891 ORDO:130 SNOMEDCT_US_2023_03_01:418818005 UMLS_CUI:C1142166 UMLS_CUI:C1721096 Bangungut Brugada type idiopathic ventricular fibrillation Dream disease Pokkuri death syndrome SUNDS sudden unexplained nocturnal death syndrome disease_ontology DOID:0050451 OMIM mapping confirmed by DO. [SN]. Brugada syndrome A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. url:http://en.wikipedia.org/wiki/Brugada_syndrome SUNDS A peroxisomal disease that is characterized by cortical atrophy, microcephaly, dysmorphic facies, muscular hypotonia and intellectual disability and has_material_basis_in mutation in the MVK gene that results in deficiency of mevalonate kinase and impaired cholesterol. biosynthesis. GARD:3588 ICD10CM:M04.1 MESH:D054078 MIM:610377 NCI:C84890 ORDO:29 SNOMEDCT_US_2023_03_01:124327008 SNOMEDCT_US_2023_03_01:234538002 UMLS_CUI:C0342731 UMLS_CUI:C0398691 UMLS_CUI:C1959626 Mevalonate Kinase Deficiency disease_ontology DOID:0050452 OMIM mapping confirmed by DO. [SN]. mevalonic aciduria A peroxisomal disease that is characterized by cortical atrophy, microcephaly, dysmorphic facies, muscular hypotonia and intellectual disability and has_material_basis_in mutation in the MVK gene that results in deficiency of mevalonate kinase and impaired cholesterol. biosynthesis. url:https://rarediseases.info.nih.gov/diseases/3588/mevalonic-aciduria A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation. GARD:12291 ICD10CM:Q04.3 MESH:D054082 MIM:PS607432 NCI:C103921 ORDO:102009 SNOMEDCT_US_2023_03_01:204036008 SNOMEDCT_US_2023_03_01:23024003 UMLS_CUI:C0266463 UMLS_CUI:C0266483 disease_ontology DOID:0050453 Xref MGI. OMIM mapping confirmed by DO. [SN]. lissencephaly A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation. url:http://en.wikipedia.org/wiki/Lissencephaly url:http://www.ninds.nih.gov/disorders/lissencephaly/lissencephaly.htm A congenital nervous system abnormality characterized by non proper migration of neurons during the early development of the fetal brain. MESH:D054091 MIM:300049 MIM:608097 MIM:608098 MIM:612881 MIM:615544 ORDO:98892 SNOMEDCT_US_2023_03_01:448227009 SNOMEDCT_US_2023_03_01:816068000 UMLS_CUI:C1848213 UMLS_CUI:C1868720 periventricular heterotopia disease_ontology DOID:0050454 Xref MGI. OMIM mapping confirmed by DO. [SN]. periventricular nodular heterotopia A congenital nervous system abnormality characterized by non proper migration of neurons during the early development of the fetal brain. url:http://ghr.nlm.nih.gov/condition/periventricular-heterotopia disease_ontology DOID:0050455 obsolete arachnodactyly true A primary bacterial infectious disease that results_in infection located_in skin or located_in subcutaneous tissue, has_material_basis_in Mycobacterium ulcerans, which could be transmitted_by insects. The bacterium produces a toxin, named mycolactone, which causes subcutaneous fat necrosis and inhibits an immune response. The infection has_symptom nodule, which is a painless, mobile swelling in the skin. GARD:9520 ICD10CM:A31.1 MESH:D054312 NCI:C84604 SNOMEDCT_US_2023_03_01:186343005 UMLS_CUI:C0085568 Bairnsdale ulcer Daintree ulcer Mossman ulcer Searl ulcer Searle's ulcer disease_ontology DOID:0050456 Buruli ulcer disease A primary bacterial infectious disease that results_in infection located_in skin or located_in subcutaneous tissue, has_material_basis_in Mycobacterium ulcerans, which could be transmitted_by insects. The bacterium produces a toxin, named mycolactone, which causes subcutaneous fat necrosis and inhibits an immune response. The infection has_symptom nodule, which is a painless, mobile swelling in the skin. url:http://en.wikipedia.org/wiki/Buruli_ulcer url:http://www.who.int/mediacentre/factsheets/fs199/en/ A male infertility disease characterized by male sterility, has_material_basis_in azospermia without abnormal sexual development. GARD:8406 MESH:D054331 NCI:C168988 SNOMEDCT_US_2023_03_01:73465006 UMLS_CUI:C1384583 DEL CASTILLO SYNDROME Germinal Cell Aplasia disease_ontology DOID:0050457 OMIM mapping confirmed by DO. [SN]. Sertoli cell-only syndrome A male infertility disease characterized by male sterility, has_material_basis_in azospermia without abnormal sexual development. url:https://rarediseases.info.nih.gov/diseases/8406/sertoli-cell-only-syndrome A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes. GARD:9884 ICD10CM:C93.3 ICDO:9946/3 MESH:D054429 MIM:607785 NCI:C9233 SNOMEDCT_US_2023_03_01:445227008 UMLS_CUI:C0349639 disease_ontology DOID:0050458 OMIM mapping confirmed by DO. [SN]. juvenile myelomonocytic leukemia A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes. url:https://rarediseases.org/rare-diseases/juvenile-myelomonocytic-leukemia/ A phosphorus metabolism disease characterized by hyperphosphatemia and abnormal deposits of phosphate and calcium in joints and soft tissues, results from abnormal phosphorus metabolism and has_material_basis_in mutations in the FGF23, GALNT3 or KL gene. MESH:D054559 NCI:C113750 SNOMEDCT_US_2023_03_01:20165001 UMLS_CUI:C0085681 disease_ontology DOID:0050459 hyperphosphatemia A phosphorus metabolism disease characterized by hyperphosphatemia and abnormal deposits of phosphate and calcium in joints and soft tissues, results from abnormal phosphorus metabolism and has_material_basis_in mutations in the FGF23, GALNT3 or KL gene. url:https://ghr.nlm.nih.gov/condition/hyperphosphatemic-familial-tumoral-calcinosis A chromosomal deletion syndrome that is characterized by distinct craniofacial features, hypotonia and intellectual disability and has_material_basis_in a hemizygous deletion of chromosome 4p16.3. DOID:6684 GARD:7896 ICD10CM:Q93.3 MESH:D054877 MIM:194190 NCI:C35528 ORDO:280 SNOMEDCT_US_2023_03_01:17122004 UMLS_CUI:C0796117 UMLS_CUI:C1956097 4p deletion syndrome PITT SYNDROME Pitt-Rogers-Danks Syndrome chromosome 4p16.3 deletion syndrome disease_ontology DOID:0050460 OMIM mapping confirmed by DO. [LS]. Wolf-Hirschhorn syndrome A chromosomal deletion syndrome that is characterized by distinct craniofacial features, hypotonia and intellectual disability and has_material_basis_in a hemizygous deletion of chromosome 4p16.3. url:https://rarediseases.info.nih.gov/diseases/7896/wolf-hirschhorn-syndrome A lysosomal storage disease that is characterized by delayed speech at 2-3 years of age, has_material_basis_in mutations in the AGA gene that result in the absence or shortage of the aspartylglucosaminidase enzyme in lysosomes, preventing the normal breakdown of glycoproteins. GARD:5854 ICD10CM:E77.1 MESH:D054880 MIM:208400 NCI:C61273 SNOMEDCT_US_2023_03_01:54954004 UMLS_CUI:C0268225 aspartylglucosaminidase deficiency aspartylglycosaminuria glycosylasparaginase deficiency disease_ontology DOID:0050461 OMIM mapping confirmed by DO. [SN]. aspartylglucosaminuria MESH:D054880 A lysosomal storage disease that is characterized by delayed speech at 2-3 years of age, has_material_basis_in mutations in the AGA gene that result in the absence or shortage of the aspartylglucosaminidase enzyme in lysosomes, preventing the normal breakdown of glycoproteins. url:https://ghr.nlm.nih.gov/condition/aspartylglucosaminuria An Antley-Bixler syndrome that is characterized at birth or prenatally by malformations and deformities affecting the majority of the skeleton and other areas of the body with autosomal recessive inheritance of the FGFR2 gene. MIM:201750 SNOMEDCT_US_2021_09_01:62964007 trapezoidocephaly-synostosis syndrome disease_ontology DOID:0050462 OMIM mapping confirmed by DO. [SN]. Antley-Bixler syndrome with disordered steroidogenesis MESH:D054882 An Antley-Bixler syndrome that is characterized at birth or prenatally by malformations and deformities affecting the majority of the skeleton and other areas of the body with autosomal recessive inheritance of the FGFR2 gene. url:http://en.wikipedia.org/wiki/Antley-Bixler_syndrome url:https://pubmed.ncbi.nlm.nih.gov/35070845/ An osteochondrodysplasia that has_material_basis_in heterozygous mutation in the SOX9 gene on chromosome 17q24 and that is characterized by congenital shortness and bowing of long tubular bones, especially in the lower extremities, as well as by hypoplastic scapulae, narrow iliac wings, and nonmineralized thoracic pedicles. GARD:10027 MESH:D055036 MIM:114290 NCI:C120205 NCI:C84609 ORDO:140 UMLS_CUI:C1861922 UMLS_CUI:C1861923 Acampomelic Campomelic Dysplasia disease_ontology DOID:0050463 OMIM mapping confirmed by DO. [SN]. campomelic dysplasia An osteochondrodysplasia that has_material_basis_in heterozygous mutation in the SOX9 gene on chromosome 17q24 and that is characterized by congenital shortness and bowing of long tubular bones, especially in the lower extremities, as well as by hypoplastic scapulae, narrow iliac wings, and nonmineralized thoracic pedicles. url:http://en.wikipedia.org/wiki/Campomelic_dysplasia url:http://ghr.nlm.nih.gov/condition/campomelic-dysplasia url:http://www.healthline.com/galecontent/campomelic-dysplasia-1 A lipid storage disease that is characterized by abnormalities in swallowing, cognition, joint function, and central nervous system due to a deficiency in the enzyme ceramidase that results in sphingolipids deposition. GARD:6426 MESH:D055577 MIM:228000 NCI:C84710 SNOMEDCT_US_2023_03_01:79935000 UMLS_CUI:C0268255 Farber disease N-laurylsphingosine deacylase deficiency acid ceramidase deficiency disease_ontology DOID:0050464 OMIM mapping confirmed by DO. [SN]. Farber lipogranulomatosis A lipid storage disease that is characterized by abnormalities in swallowing, cognition, joint function, and central nervous system due to a deficiency in the enzyme ceramidase that results in sphingolipids deposition. url:https://en.wikipedia.org/wiki/Farber_disease A Lynch syndrome that is characterized by a propensity to develop cancers of the gastrointestinal tract, genitourinary tract, and skin that has_material_basis_in mutations in DNA mismatch repair genes. GARD:6821 MESH:D055653 MIM:158320 NCI:C84905 SNOMEDCT_US_2023_03_01:403824007 UMLS_CUI:C1321489 disease_ontology DOID:0050465 OMIM mapping confirmed by DO. [SN]. Muir-Torre syndrome A Lynch syndrome that is characterized by a propensity to develop cancers of the gastrointestinal tract, genitourinary tract, and skin that has_material_basis_in mutations in DNA mismatch repair genes. url:https://en.wikipedia.org/wiki/Muir%E2%80%93Torre_syndrome A syndrome that is characterized by increased risk of aortic aneurysm and dissection, elongated limbs, hypertelorism, bifid uvula and easy skin bruising due to mutations in TGFB3 that results in connective tissue defects. GARD:10788 MESH:D055947 NCI:C75006 ORDO:60030 SNOMEDCT_US_2023_03_01:446263001 UMLS_CUI:C1836635 UMLS_CUI:C2697932 disease_ontology DOID:0050466 Xref MGI. OMIM mapping confirmed by DO. [SN]. Loeys-Dietz syndrome A syndrome that is characterized by increased risk of aortic aneurysm and dissection, elongated limbs, hypertelorism, bifid uvula and easy skin bruising due to mutations in TGFB3 that results in connective tissue defects. url:https://en.wikipedia.org/wiki/Loeys%E2%80%93Dietz_syndrome A skin disease that is characterized by areas of sharply demarcated, brown hyperkeratosis and has_material_basis_in mutations in genes encoding for connexin channels proteins in the epidermis. MESH:D056266 MIM:PS133200 NCI:C84696 ORDO:317 SNOMEDCT_US_2023_03_01:70041004 UMLS_CUI:C0265961 UMLS_CUI:C1851480 Erythrokeratodermia Figurata Variabilis Greither Disease disease_ontology DOID:0050467 OMIM mapping confirmed by DO. [SN]. erythrokeratodermia variabilis MESH:D056266 A skin disease that is characterized by areas of sharply demarcated, brown hyperkeratosis and has_material_basis_in mutations in genes encoding for connexin channels proteins in the epidermis. url:https://en.wikipedia.org/wiki/Erythrokeratodermia_variabilis A syndrome that is characterized by an accumulation of protein-rich fluid (lymph) in the soft layers of tissue under the skin resulting in pleural effusions, lymphedema (due to lymphatic hypoplasia) and yellow dystrophic nails hat lack a cuticle, grow slowly, and are loose or detached. GARD:184 ICD10CM:L60.5 MESH:D056684 MIM:153300 NCI:C85238 SNOMEDCT_US_2023_03_01:400211001 UMLS_CUI:C0221348 disease_ontology DOID:0050468 OMIM mapping confirmed by DO. [SN]. yellow nail syndrome A syndrome that is characterized by an accumulation of protein-rich fluid (lymph) in the soft layers of tissue under the skin resulting in pleural effusions, lymphedema (due to lymphatic hypoplasia) and yellow dystrophic nails hat lack a cuticle, grow slowly, and are loose or detached. url:https://www.ncbi.nlm.nih.gov/pubmed/28241848 A RASopathy characterized by craniofacial dysmorphology, cardiac defects, mild mental retardation, and high birth weight followed by a failure to thrive and developmental delays. GARD:1550 MESH:D056685 MIM:218040 NCI:C84652 SNOMEDCT_US_2023_03_01:205803001 UMLS_CUI:C0587248 FCS SYNDROME Faciocutaneoskeletal Syndrome disease_ontology DOID:0050469 OMIM mapping confirmed by DO. [SN]. Costello syndrome A RASopathy characterized by craniofacial dysmorphology, cardiac defects, mild mental retardation, and high birth weight followed by a failure to thrive and developmental delays. url:https://www.ncbi.nlm.nih.gov/pubmed/17250658 url:https://www.ncbi.nlm.nih.gov/pubmed/907573 A syndrome that is characterized by protuberant and low-set ears, flaring nostrils, thick lips, enlarged secondary sex organs and overwhelming insulin resistance and has_material_basis_in mutation within the INSR gene causing abnormalities in the insulin receptor. MESH:D056731 MIM:246200 NCI:C131000 NCI:C84676 ORDO:508 SNOMEDCT_US_2023_03_01:111307005 SNOMEDCT_US_2023_03_01:33559001 UMLS_CUI:C0265344 UMLS_CUI:C0271695 Leprechaunism disease_ontology DOID:0050470 OMIM mapping confirmed by DO. [SN]. Donohue syndrome A syndrome that is characterized by protuberant and low-set ears, flaring nostrils, thick lips, enlarged secondary sex organs and overwhelming insulin resistance and has_material_basis_in mutation within the INSR gene causing abnormalities in the insulin receptor. url:https://en.wikipedia.org/wiki/Donohue_syndrome A syndrome characterized by myxomas, spotty pigmentation of the skin and endocrine overactivity. GARD:1119 MESH:D056733 MIM:160980 MIM:605244 MIM:608837 NCI:C4705 ORDO:1359 SNOMEDCT_US_2023_03_01:733491005 UMLS_CUI:C0406810 UMLS_CUI:C1854540 UMLS_CUI:C2607929 Carney Complex, Type 1 Carney Complex, Type 2 Carney Syndrome Carney complex variant LAMB Syndrome NAME Syndrome disease_ontology DOID:0050471 Xref MGI. OMIM mapping confirmed by DO. [SN]. Carney complex A syndrome characterized by myxomas, spotty pigmentation of the skin and endocrine overactivity. url:http://en.wikipedia.org/wiki/Carney_complex url:http://ghr.nlm.nih.gov/condition/carney-complex A hair disease that is characterized by short, easily broken hair that results in alopecia and has_material_basis_in mutations in genes for type II hair cortex keratins. GARD:93 ICD10CM:Q84.1 MESH:D056734 MIM:158000 NCI:C84894 SNOMEDCT_US_2023_03_01:69488000 UMLS_CUI:C0546966 disease_ontology DOID:0050472 OMIM mapping confirmed by DO. [SN]. monilethrix A hair disease that is characterized by short, easily broken hair that results in alopecia and has_material_basis_in mutations in genes for type II hair cortex keratins. url:https://ghr.nlm.nih.gov/condition/monilethrix A syndrome that is characterized by multiorgan dysfunction. The key features are childhood obesity, blindness due to congenital retinal dystrophy, and sensorineural hearing loss with autosomal recessive inheritance and has_material_basis_in mutations in the ALMS1 gene. MESH:D056769 MIM:203800 NCI:C84549 SNOMEDCT_US_2023_03_01:63702009 UMLS_CUI:C0268425 disease_ontology DOID:0050473 OMIM mapping confirmed by DO. [SN]. Alstrom syndrome MESH:D056769 A syndrome that is characterized by multiorgan dysfunction. The key features are childhood obesity, blindness due to congenital retinal dystrophy, and sensorineural hearing loss with autosomal recessive inheritance and has_material_basis_in mutations in the ALMS1 gene. url:http://en.wikipedia.org/wiki/Alstrom_syndrome A skin disease that is characterized by chronic skin inflammation, trichorrhexis invaginata, atopic dermatitis and has_material_basis_in mutations in the SPINK5 gene resulting in reduced capacity to inhibit serine proteases expressed in the skin. GARD:7182 MIM:256500 ORDO:634 SNOMEDCT_US_2023_03_01:312514006 UMLS_CUI:C0265962 disease_ontology DOID:0050474 OMIM mapping confirmed by DO. [SN]. Netherton syndrome A skin disease that is characterized by chronic skin inflammation, trichorrhexis invaginata, atopic dermatitis and has_material_basis_in mutations in the SPINK5 gene resulting in reduced capacity to inhibit serine proteases expressed in the skin. url:https://ghr.nlm.nih.gov/condition/netherton-syndrome A syndrome characterized by short stature, brachycephaly and other facial abnormalities, brachydactyly, joint stiffness and distinctive ocular abnormalities. GARD:4936 MESH:D056846 MIM:277600 MIM:608328 MIM:613195 MIM:614819 MIM:PS277600 NCI:C85226 ORDO:3449 SNOMEDCT_US_2023_03_01:205801004 UMLS_CUI:C0265313 UMLS_CUI:C1869114 UMLS_CUI:C1869115 GEMSS syndrome Marchesani-Weill Syndrome Mesodermal Dysmorphodystrophy, Congenital Spherophakia Brachymorphia Syndrome congenital mesodermal dystrophy disease_ontology DOID:0050475 Xref MGI. OMIM mapping confirmed by DO. [LS]. Weill-Marchesani syndrome A syndrome characterized by short stature, brachycephaly and other facial abnormalities, brachydactyly, joint stiffness and distinctive ocular abnormalities. url:http://en.wikipedia.org/wiki/Weill-Marchesani_syndrome url:http://ghr.nlm.nih.gov/condition/weill-marchesani-syndrome A 3-methylglutaconic aciduria that has_material_basis_in X-linked inheritance of the tafazzin gene and is characterized by decreased production of an enzyme required to produce cardiolipin. GARD:5890 ICD10CM:E78.71 MESH:D056889 MIM:302060 NCI:C84585 ORDO:111 SNOMEDCT_US_2023_03_01:297231002 UMLS_CUI:C0574083 3-methylglutaconicaciduria type 2 3-methylglutaconicaciduria type II MGA Type 2 MGA type II disease_ontology DOID:0050476 OMIM mapping confirmed by DO. [SN]. Barth syndrome MESH:D056889 A 3-methylglutaconic aciduria that has_material_basis_in X-linked inheritance of the tafazzin gene and is characterized by decreased production of an enzyme required to produce cardiolipin. url:http://en.wikipedia.org/wiki/Barth_syndrome url:http://www.ninds.nih.gov/disorders/barth/barth.htm A renal tubular transport disease that is characterized by hypertension and hypokalemia caused by dysregulation of epithelial sodium channels causing over expression of the channel. GARD:7381 MESH:D056929 MIM:177200 NCI:C84827 SNOMEDCT_US_2023_03_01:707749005 UMLS_CUI:C0221043 Liddle's syndrome Pseudoaldosteronism disease_ontology DOID:0050477 OMIM mapping confirmed by DO. [SN]. Liddle syndrome A renal tubular transport disease that is characterized by hypertension and hypokalemia caused by dysregulation of epithelial sodium channels causing over expression of the channel. url:https://en.wikipedia.org/wiki/Liddle%27s_syndrome disease_ontology DOID:0050478 obsolete primary Escherichia coli infectious disease true Klebsiella infection disease_ontology DOID:0050479 obsolete commensal Klebsiella infectious disease true A typhus that has_material_basis_in Rickettsia prowazekii, which is transmitted by human body louse (Pediculus humanus corporis). The infection has_symptom high fever, has_symptom cough, has_symptom rash, has_symptom severe muscle pain, has_symptom chills, has_symptom falling blood pressure, has_symptom stupor, has_symptom sensitivity to light, and has_symptom delirium. sylvatic typhus disease_ontology DOID:0050480 epidemic typhus A typhus that has_material_basis_in Rickettsia prowazekii, which is transmitted by human body louse (Pediculus humanus corporis). The infection has_symptom high fever, has_symptom cough, has_symptom rash, has_symptom severe muscle pain, has_symptom chills, has_symptom falling blood pressure, has_symptom stupor, has_symptom sensitivity to light, and has_symptom delirium. url:http://en.wikipedia.org/wiki/Epidemic_typhus A typhus that has_material_basis_in Rickettsia typhi or has_material_basis_in Rickettsia felis, which are transmitted by fleas (Xenopsylla cheopis). The infection has symptom headache, has symptom fever, has symptom chills, has symptom myalgia, has symptom nausea, has symptom vomiting, has symptom cough and has symptom rash. DOID:0050028 DOID:0050029 DOID:0050030 DOID:0050057 DOID:0050058 Rat-Flea Typhus Rickettsia felis spotted fever Urban Typhus of Malaya cat flea rickettsiosis fleaborne typhus murine typhus toulon typhus urban typhus disease_ontology Shop typhus DOID:0050481 endemic typhus A typhus that has_material_basis_in Rickettsia typhi or has_material_basis_in Rickettsia felis, which are transmitted by fleas (Xenopsylla cheopis). The infection has symptom headache, has symptom fever, has symptom chills, has symptom myalgia, has symptom nausea, has symptom vomiting, has symptom cough and has symptom rash. url:http://en.wikipedia.org/wiki/Murine_typhus disease_ontology DOID:0050482 obsolete lymphangitis-associated rickettsiosis true disease_ontology DOID:0050483 obsolete Rickettsia aeschlimannii spotted fever true A spotted fever that has_material_basis_in Rickettsia helvetica, which is transmitted_by ticks (Ixodes sp). The infection has_symptom fever, has_symptom headache, has_symptom myalgia. Rickettsia helvetica spotted fever disease_ontology DOID:0050484 aneruptive fever A spotted fever that has_material_basis_in Rickettsia helvetica, which is transmitted_by ticks (Ixodes sp). The infection has_symptom fever, has_symptom headache, has_symptom myalgia. url:http://jcm.asm.org/cgi/reprint/42/2/816 url:http://www.cdc.gov/otherspottedfever/index.html A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia. GARD:120 MESH:C537582 Sennetsu ehrlichiosis disease_ontology DOID:0050485 sennetsu fever A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia. url:https://rarediseases.org/rare-diseases/sennetsu-fever/ A skin disease that is characterized by a rash that results from a variety of causes including bacteria, viruses, toxins, drugs and autoimmune disorders. ICD10CM:R21 ICD9CM:782.1 MESH:D005076 NCI:C111884 SNOMEDCT_US_2023_03_01:112625008 UMLS_CUI:C0015230 disease_ontology DOID:0050486 exanthem A skin disease that is characterized by a rash that results from a variety of causes including bacteria, viruses, toxins, drugs and autoimmune disorders. url:https://en.wikipedia.org/wiki/Exanthem An exanthem that is characterized by a diffuse, reddened, blanchable, finely papular, sandpaper like rash due to infection by group A streptococcus and the production of an erythrogenic toxin. disease_ontology DOID:0050487 bacterial exanthem An exanthem that is characterized by a diffuse, reddened, blanchable, finely papular, sandpaper like rash due to infection by group A streptococcus and the production of an erythrogenic toxin. url:https://en.wikipedia.org/wiki/Scarlet_fever#Rash A congenital syphilis that is manifested during the first 3 months of life. The infection has_symptom skin lesions, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom failure to thrive, has_symptom blood-stained nasal discharge, has_symptom perioral fissures, has_symptom meningitis, has_symptom choroiditis, has_symptom hydrocephalus, has_symptom seizures, has_symptom intellectual disability, has_symptom osteochondritis, and has_symptom pseudoparalysis. disease_ontology DOID:0050488 early congenital syphilis A congenital syphilis that is manifested during the first 3 months of life. The infection has_symptom skin lesions, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom failure to thrive, has_symptom blood-stained nasal discharge, has_symptom perioral fissures, has_symptom meningitis, has_symptom choroiditis, has_symptom hydrocephalus, has_symptom seizures, has_symptom intellectual disability, has_symptom osteochondritis, and has_symptom pseudoparalysis. url:http://www.merckmanuals.com/professional/sec19/ch279/ch279d.html A goiter characterized by a multinodular enlargement of the thyroid gland. MIM:138800 MIM:300273 MIM:606082 MIM:PS138800 ORDO:276399 disease_ontology DOID:0050489 Xref MGI. OMIM mapping confirmed by DO. [SN]. multinodular goiter A goiter characterized by a multinodular enlargement of the thyroid gland. url:http://en.wikipedia.org/wiki/Multinodular_goitre A tertiary neurosyphilis that results when chronic meningoencephalitis causes destruction of cortical parenchyma. The infection has_symptom irritability, has_symptom difficulty concentrating, has_symptom deterioration of memory, has_symptom defective judgment, has_symptom headaches, has_symptom insomnia, has_symptom fatigue, and has_symptom lethargy. disease_ontology DOID:0050490 parenchymatous neurosyphilis A tertiary neurosyphilis that results when chronic meningoencephalitis causes destruction of cortical parenchyma. The infection has_symptom irritability, has_symptom difficulty concentrating, has_symptom deterioration of memory, has_symptom defective judgment, has_symptom headaches, has_symptom insomnia, has_symptom fatigue, and has_symptom lethargy. url:http://www.merckmanuals.com/professional/sec14/ch194/ch194i.html?qt=latent%20syphylis&alt=sh A tertiary neurosyphilis that results in inflammation located_in arteries of the brain or located_in arteries of spinal cord. The infection has_symptom headache, has_symptom neck stiffness, has_symptom dizziness, has_symptom behavioral abnormalities, has _symptom poor concentration, has_symptom memory loss, has _symptom lassitude, has_symptom insomnia, has_symptom blurred vision, has_symptom weakness and wasting of shoulder-girdle and arm muscles, has_symptom slowly progressive leg weakness with urinary or fecal incontinence or both, and has_symptom paralysis of the legs due to thrombosis of spinal arteries. disease_ontology DOID:0050491 meningovascular neurosyphilis A tertiary neurosyphilis that results in inflammation located_in arteries of the brain or located_in arteries of spinal cord. The infection has_symptom headache, has_symptom neck stiffness, has_symptom dizziness, has_symptom behavioral abnormalities, has _symptom poor concentration, has_symptom memory loss, has _symptom lassitude, has_symptom insomnia, has_symptom blurred vision, has_symptom weakness and wasting of shoulder-girdle and arm muscles, has_symptom slowly progressive leg weakness with urinary or fecal incontinence or both, and has_symptom paralysis of the legs due to thrombosis of spinal arteries. url:http://www.merckmanuals.com/professional/sec14/ch194/ch194i.html?qt=latent%20syphylis&alt=sh disease_ontology DOID:0050492 obsolete tertiary syphilitic encephalitis true disease_ontology DOID:0050493 obsolete tertiary syphilitic meningitis true A dsDNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Papillomaviridae viruses. disease_ontology DOID:0050494 obsolete Papillomaviridae infectious disease true A dsDNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Papillomaviridae viruses. url:http://en.wikipedia.org/wiki/Papillomaviridae A viral infectious disease that results_in infection in infants and children, located_in skin, has_material_basis_in Human herpesvirus 6 or has_material_basis_in Human herpesvirus 7 and has_symptom sudden high fever, and has_symptom red rash that occurs first on the trunk then spreading to legs and neck. ICD10CM:B08.2 ICD9CM:058.1 MESH:D005077 SNOMEDCT_US_2023_03_01:54385001 UMLS_CUI:C0015231 Roseola Infantum Sixth Disease disease_ontology DOID:0050495 exanthema subitum A viral infectious disease that results_in infection in infants and children, located_in skin, has_material_basis_in Human herpesvirus 6 or has_material_basis_in Human herpesvirus 7 and has_symptom sudden high fever, and has_symptom red rash that occurs first on the trunk then spreading to legs and neck. url:http://en.wikipedia.org/wiki/Exanthema_subitum A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Banna virus, which is transmitted_by Culex, and transmitted_by Anopheles mosquitoes. The infection has_symptom fever, and has_symptom headache. disease_ontology DOID:0050496 obsolete Banna virus encephalitis true A ssDNA virus infectious disease that results_in infection in humans, has_material_basis_in Anelloviridae viruses. disease_ontology DOID:0050497 obsolete Anelloviridae infectious disease true A ssDNA virus infectious disease that results_in infection in humans, has_material_basis_in Anelloviridae viruses. url:http://en.wikipedia.org/wiki/Anelloviridae A DNA virus infectious disease that results_in infection, has_material_basis_in dsDNA viruses, which possess double-stranded DNA. double stranded DNA virus infectious disease dsDNA virus infection disease_ontology DOID:0050498 obsolete dsDNA virus infectious disease true A DNA virus infectious disease that results_in infection, has_material_basis_in dsDNA viruses, which possess double-stranded DNA. url:http://en.wikipedia.org/wiki/Viral_classification A DNA virus infectious disease that results_in infection, has_material_basis_in ssDNA viruses, which possess single-stranded DNA. single stranded DNA virus infectious disease