obsolete Mansonella streptocerca infectious disease
type: Class
IAO_0000115: A mansonelliasis that involves parasitic infection by the nematode Mansonella streptocerca, which resides in the dermis and subcutaneous tissue causing pruritus, papular eruptions and pigmentation changes. Midges transmit the disease.
has OBO namespace: disease_ontology
id: DOID:0050011
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Mansonella streptocerca infectious disease
annotated property: IAO_0000115
annotated target: A mansonelliasis that involves parasitic infection by the nematode Mansonella streptocerca, which resides in the dermis and subcutaneous tissue causing pruritus, papular eruptions and pigmentation changes. Midges transmit the disease.
type: ECO_0007637
has db xref: url:http://www.dpd.cdc.gov/dpdx/HTML/Filariasis.htm

chikungunya
type: Class
IAO_0000115: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus (Alphavirus chikungunya), which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash.
has db xref: GARD:6038
has exact synonym: Chikungunya fever
has OBO namespace: disease_ontology
id: DOID:0050012
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: chikungunya
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus (Alphavirus chikungunya), which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Chikungunya_virus
has db xref: url:https://www.cdc.gov/chikungunya/about/

obsolete Ehrlichia ewingii ehrlichiosis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050024
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease
deprecated: true

African tick-bite fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia africae, which is transmitted_by ticks (Amblyomma hebraeum and Amblyomma variegatum). The infection has_symptom fever, has_symptom eschar and has_symptom maculopapular rash.
has alternative id: DOID:0050034
has alternative id: DOID:0050036
has exact synonym: Rickettsia africae spotted fever
has exact synonym: south african tick-bite fever
has OBO namespace: disease_ontology
id: DOID:0050035
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: African tick-bite fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia africae, which is transmitted_by ticks (Amblyomma hebraeum and Amblyomma variegatum). The infection has_symptom fever, has_symptom eschar and has_symptom maculopapular rash.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://jcm.asm.org/cgi/reprint/42/2/816
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

Astrakhan spotted fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia conorii subsp caspia, which is transmitted_by ticks (Rhipicephalus pumilio and Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities.
has OBO namespace: disease_ontology
id: DOID:0050041
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Astrakhan spotted fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia conorii subsp caspia, which is transmitted_by ticks (Rhipicephalus pumilio and Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/7985764/

Indian tick typhus
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia conorii subsp indica, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities.
has OBO namespace: disease_ontology
id: DOID:0050042
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Indian tick typhus
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia conorii subsp indica, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.biomedcentral.com/1471-2180/5/11
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

Israeli tick typhus
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia conorii subsp israelensis, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities.
has OBO namespace: disease_ontology
has related synonym: Israeli spotted fever
id: DOID:0050043
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Israeli tick typhus
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia conorii subsp israelensis, which is transmitted_by ticks (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash on extremities.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.biomedcentral.com/1471-2180/5/11
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

Far Eastern spotted fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia heilongjiangensis, which is transmitted_by ticks (Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom maculopapular rash, and has_symptom regional adenopathy.
has exact synonym: Rickettsia heilongjiangensis spotted fever
has OBO namespace: disease_ontology
id: DOID:0050046
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Far Eastern spotted fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia heilongjiangensis, which is transmitted_by ticks (Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom maculopapular rash, and has_symptom regional adenopathy.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/eid/content/16/8/pdfs/1306.pdf
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

Japanese spotted fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia japonica, which is transmitted_by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has_symptom fever, has_symptom eschars, has_symptom regional adenopathy, and has_symptom rash on extremities.
has alternative id: DOID:0050049
has exact synonym: Rickettsia japonica spotted fever
has exact synonym: oriental spotted fever
has OBO namespace: disease_ontology
id: DOID:0050050
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Japanese spotted fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia japonica, which is transmitted_by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has_symptom fever, has_symptom eschars, has_symptom regional adenopathy, and has_symptom rash on extremities.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html
has db xref: url:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627607/pdf/9204291.pdf

Rickettsia parkeri spotted fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia parkeri, which is transmitted_by Gulf Coast tick (Amblyomma maculatum). The infection has_symptom fever, has_symptom headache, has_symptom eschar, and has_symptom rash.
has exact synonym: maculatum infection
has OBO namespace: disease_ontology
id: DOID:0050051
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Rickettsia parkeri spotted fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia parkeri, which is transmitted_by Gulf Coast tick (Amblyomma maculatum). The infection has_symptom fever, has_symptom headache, has_symptom eschar, and has_symptom rash.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://cmr.asm.org/cgi/content/full/18/4/719#Rickettsia_parkeri
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

Rocky Mountain spotted fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, and has_symptom maculopapular rash progressing into papular or petechial rash.
has alternative id: DOID:0050056
has alternative id: DOID:1708
has db xref: GARD:7585
has db xref: MESH:D012373
has exact synonym: Tick typhus
has OBO namespace: disease_ontology
has related synonym: Brazilian spotted
has related synonym: Choix
has related synonym: Exanthematic typhus of Sao Paulo
has related synonym: Fiebre maculosa
has related synonym: Fiebre manchada
has related synonym: Sao Paulo typhus
has related synonym: So Paulo fever
has related synonym: Tobia fever
id: DOID:0050052
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Rocky Mountain spotted fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, and has_symptom maculopapular rash progressing into papular or petechial rash.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://cmr.asm.org/cgi/content/full/18/4/719#Rickettsia_rickettsii_%28Rocky_Mountain_spotted_fever%29
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

oropharyngeal anthrax
type: Class
subclass of: gastrointestinal anthrax
IAO_0000115: A gastrointestinal anthrax that results in infection located in mucosa of oropharynx, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.
has OBO namespace: disease_ontology
id: DOID:0050059
in subset: DO infectious disease slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: oropharyngeal anthrax
annotated property: IAO_0000115
annotated target: A gastrointestinal anthrax that results in infection located in mucosa of oropharynx, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/3934300

erysipeloid
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection located_in skin, has_material_basis_in Erysipelothrix rhusiopathiae, which is transmitted_by contact with infected animals. The infection has_symptom redness of skin, has_symptom tenderness of skin and has_symptom warmth of skin.
has db xref: MESH:D004887
has OBO namespace: disease_ontology
id: DOID:0050061
in subset: DO infectious disease slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: erysipeloid
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection located_in skin, has_material_basis_in Erysipelothrix rhusiopathiae, which is transmitted_by contact with infected animals. The infection has_symptom redness of skin, has_symptom tenderness of skin and has_symptom warmth of skin.
has db xref: url:https://en.wikipedia.org/wiki/Erysipeloid

obsolete abortive plague
type: Class
has OBO namespace: disease_ontology
id: DOID:0050063
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete cutaneous listeriosis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050065
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Listeria meningoencephalitis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050066
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Listeria septicaemia
type: Class
has OBO namespace: disease_ontology
id: DOID:0050067
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Yersinia pestis infectious disease
type: Class
has OBO namespace: disease_ontology
id: DOID:0050069
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete plague meningitis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050070
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

La Crosse encephalitis
type: Class
IAO_0000115: A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in La Crosse virus (Orthobunyavirus lacrosseense), which is primarily transmitted_by treehole mosquito (Ochlerotatus triseriatus) but also Asian tiger mosquito (Aedes albopictus) and Asian bush mosquito (Aedes japonicus). The infection has_symptom seizures, has_symptom headache, has_symptom fever, has_symptom coma, and has_symptom paralysis.
has alternative id: DOID:10840
has db xref: ICD10CM:A83.5
has db xref: ICD9CM:062.5
has db xref: MESH:D004670
has db xref: SNOMEDCT_US_2023_03_01:69627004
has db xref: UMLS_CUI:C0014053
has exact synonym: California Encephalitis
has exact synonym: California virus encephalitis
has exact synonym: Neuroinvasive California encephalitis virus infection
has OBO namespace: disease_ontology
id: DOID:0050118
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: La Crosse encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in La Crosse virus (Orthobunyavirus lacrosseense), which is primarily transmitted_by treehole mosquito (Ochlerotatus triseriatus) but also Asian tiger mosquito (Aedes albopictus) and Asian bush mosquito (Aedes japonicus). The infection has_symptom seizures, has_symptom headache, has_symptom fever, has_symptom coma, and has_symptom paralysis.
type: ECO_0007637
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/La_Crosse_encephalitis
has db xref: url:https://www.cdc.gov/la-crosse-encephalitis/about/
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK562248/

obsolete West Nile virus neurological syndrome
type: Class
IAO_0000115: A West Nile virus infectious disease that has_material_basis_in West Nile virus, which can cause meningitis, encephalitis, acute laccid paralysis, Parkingsonian-like conditions or movement disorder.
has exact synonym: WNND
has exact synonym: WNNS
has exact synonym: West nile neuroinvasive disease
has OBO namespace: disease_ontology
id: DOID:0050119
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete West Nile virus neurological syndrome
annotated property: IAO_0000115
annotated target: A West Nile virus infectious disease that has_material_basis_in West Nile virus, which can cause meningitis, encephalitis, acute laccid paralysis, Parkingsonian-like conditions or movement disorder.
has db xref: url:http://www.phac-aspc.gc.ca/wnv-vwn/hmncasedef-eng.php

dengue shock syndrome
type: Class
subclass of: dengue disease
IAO_0000115: A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth.
has exact synonym: DSS
has OBO namespace: disease_ontology
id: DOID:0050125
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: dengue shock syndrome
annotated property: IAO_0000115
annotated target: A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Dengue_shock_syndrome
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC3097561/

Axiom
annotated source: dengue shock syndrome
annotated property: hasExactSynonym
annotated target: DSS
has synonym type: OMO_0003012

obsolete Tahyna virus encephalitis
type: Class
IAO_0000115: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Tahyna virus, which is transmitted_by Aedes, transmitted_by Culex, and transmitted_by Ochlerotatus mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures.
has exact synonym: valtice fever
has OBO namespace: disease_ontology
has related synonym: Tahyna virus infection
id: DOID:0050126
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Tahyna virus encephalitis
annotated property: IAO_0000115
annotated target: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Tahyna virus, which is transmitted_by Aedes, transmitted_by Culex, and transmitted_by Ochlerotatus mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures.
type: ECO_0007645
has db xref: url:http://www.cdc.gov/eid/content/15/2/306.htm

asymptomatic dengue
type: Class
subclass of: dengue disease
IAO_0000115: A dengue disease that results_in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted_by Aedes mosquito bite. The infection has no manifestations of symptoms.
has OBO namespace: disease_ontology
id: DOID:0050143
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: asymptomatic dengue
annotated property: IAO_0000115
annotated target: A dengue disease that results_in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted_by Aedes mosquito bite. The infection has no manifestations of symptoms.
type: ECO_0007645
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/28107858/
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/29111183/

inhalation anthrax
type: Class
subclass of: anthrax disease
IAO_0000115: An anthrax disease that results in infection located in lung lymph nodes brought on by breathing in the spores of the bacteria Bacillus anthracis. The first symptoms of inhalation anthrax are like cold or flu symptoms and can include a sore throat, mild fever and muscle aches. Later symptoms include cough, chest discomfort, shortness of breath, tiredness and muscle aches.
has db xref: MESH:C571912
has exact synonym: pulmonary anthrax
has exact synonym: respiratory anthrax
has exact synonym: wool-sorters' disease
has exact synonym: woolsorters' disease
has OBO namespace: disease_ontology
id: DOID:0050160
in subset: DO infectious disease slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: inhalation anthrax
annotated property: IAO_0000115
annotated target: An anthrax disease that results in infection located in lung lymph nodes brought on by breathing in the spores of the bacteria Bacillus anthracis. The first symptoms of inhalation anthrax are like cold or flu symptoms and can include a sore throat, mild fever and muscle aches. Later symptoms include cough, chest discomfort, shortness of breath, tiredness and muscle aches.
type: ECO_0007637
type: ECO_0007640
type: ECO_0007645
has db xref: url:https://medlineplus.gov/ency/article/001325.htm
has db xref: url:https://www.cdc.gov/anthrax/basics/types/index.html
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/11988441

obsolete Jamestown Canyon encephalitis
type: Class
IAO_0000115: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Jamestown Canyon virus, which is transmitted_by Culiseta, transmitted_by Aedes, and transmitted_by Anopheles species of mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom neck stiffness, has_symptom photophobia, has_symptom nausea, has_symptom vomiting, and has_symptom seizures.
has OBO namespace: disease_ontology
id: DOID:0050170
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Jamestown Canyon encephalitis
annotated property: IAO_0000115
annotated target: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Jamestown Canyon virus, which is transmitted_by Culiseta, transmitted_by Aedes, and transmitted_by Anopheles species of mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom neck stiffness, has_symptom photophobia, has_symptom nausea, has_symptom vomiting, and has_symptom seizures.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.cdc.gov/ncidod/dvbid/arbor/arboguid.pdf
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/10451169

obsolete snowshoe hare encephalitis
type: Class
IAO_0000115: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Snowshoe hare virus, which is transmitted_by Aedes mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures.
has OBO namespace: disease_ontology
id: DOID:0050171
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete snowshoe hare encephalitis
annotated property: IAO_0000115
annotated target: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Snowshoe hare virus, which is transmitted_by Aedes mosquitoes. The infection has_symptom headache, has_symptom fever, has_symptom anorexia, and has_symptom seizures.
has db xref: url:http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/07vol33/dr3311c-eng.php

obsolete trivittatus encephalitis
type: Class
IAO_0000115: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Trivittatus virus, which is transmitted_by Ochlerotatus trivittatus mosquito. The infection has_symptom headache, has_symptom fever, has_symptom disorientation, has_symptom tremors, has_symptom convulsions, has_symptom paralysis, and has_symptom coma.
has OBO namespace: disease_ontology
id: DOID:0050172
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete trivittatus encephalitis
annotated property: IAO_0000115
annotated target: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Trivittatus virus, which is transmitted_by Ochlerotatus trivittatus mosquito. The infection has_symptom headache, has_symptom fever, has_symptom disorientation, has_symptom tremors, has_symptom convulsions, has_symptom paralysis, and has_symptom coma.
type: ECO_0007645
has db xref: url:http://books.google.com/books?id=GcvRX19C3C8C&pg=PA235&lpg#v=onepage&q=&f=false
has db xref: url:http://www.epi.state.nc.us/epi/gcdc/manual/casedefs/ENCEPHALITIS,ARBOVIRAL_CD.pdf
has db xref: url:http://www.health.state.ny.us/diseases/communicable/arboviral/fact_sheet.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/10025535

obsolete inkoo encephalitis
type: Class
IAO_0000115: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Inkoo virus, which is transmitted_by Ochlerotatus communis mosquito. The infection has_symptom stiff neck, has_symptom lethargy, has_symptom headache, has_symptom fever, and has_symptom seizures.
has OBO namespace: disease_ontology
id: DOID:0050173
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete inkoo encephalitis
annotated property: IAO_0000115
annotated target: A California virus encephalitis that results_in inflammation located_in brain, has_material_basis_in Inkoo virus, which is transmitted_by Ochlerotatus communis mosquito. The infection has_symptom stiff neck, has_symptom lethargy, has_symptom headache, has_symptom fever, and has_symptom seizures.
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://birdflubook.com/resources/0Kallio-Kokkoxxx.pdf
has db xref: url:http://en.wikipedia.org/wiki/California_encephalitis_virus
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/8760424
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/10025535

Nipah virus encephalitis
type: Class
IAO_0000115: A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Nipah virus (Henipavirus nipahense), which is transmitted_by direct contact with sick person or animals, or their contaminated tissues. The infection has_symptom dizziness, has_symptom drowsiness, has_symptom altered consciousness, has_symptom disorientation, and has_symptom coma.
has db xref: MESH:D045464
has db xref: SNOMEDCT_US_2025_05_01:721791005
has db xref: UMLS_CUI:C4303115
has OBO namespace: disease_ontology
id: DOID:0050192
in subset: DO infectious disease slim
in subset: zoonotic infectious disease
broad match: ORDO:99825
broad match: SNOMEDCT_US_2025_05_01:406597005
broad match: UMLS_CUI:C1320202

Axiom
annotated source: Nipah virus encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Nipah virus (Henipavirus nipahense), which is transmitted_by direct contact with sick person or animals, or their contaminated tissues. The infection has_symptom dizziness, has_symptom drowsiness, has_symptom altered consciousness, has_symptom disorientation, and has_symptom coma.
type: ECO_0007637
type: ECO_0007645
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC9345211/
has db xref: url:https://www.cdc.gov/nipah-virus/about/
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK570576/
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/19141846
has db xref: url:https://www.who.int/csr/disease/nipah/en/

obsolete Lymphocytic choriomeningitis virus encephalitis
type: Class
IAO_0000115: A lymphocytic choriomeningitis that results_in inflammation located_in brain, has_material_basis_in Lymphocytic choriomeningitis virus, which is transmitted_by common house mouse, Mus musculus. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis.
has OBO namespace: disease_ontology
id: DOID:0050193
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Lymphocytic choriomeningitis virus encephalitis
annotated property: IAO_0000115
annotated target: A lymphocytic choriomeningitis that results_in inflammation located_in brain, has_material_basis_in Lymphocytic choriomeningitis virus, which is transmitted_by common house mouse, Mus musculus. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lcmv/qa.htm

Argentine hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Junin virus (Mammarenavirus juninense), which is transmitted_by rodent, Calomys musculinus. The infection has_symptom fever, has_symptom fatigue, has_symptom malaise, has_symptom leukopenia, has_symptom thrombocytopenia, and has_symptom hemorrhagic manifestations.
has OBO namespace: disease_ontology
id: DOID:0050194
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Argentine hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Junin virus (Mammarenavirus juninense), which is transmitted_by rodent, Calomys musculinus. The infection has_symptom fever, has_symptom fatigue, has_symptom malaise, has_symptom leukopenia, has_symptom thrombocytopenia, and has_symptom hemorrhagic manifestations.
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Argentine_hemorrhagic_fever
has db xref: url:http://www.jstor.org/stable/30129873?seq=1

Bolivian hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Machupo virus (Mammarenavirus machupoense), which is transmitted_by vesper mouse, Calomys callosus. The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary tracts.
has OBO namespace: disease_ontology
id: DOID:0050195
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Bolivian hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Machupo virus (Mammarenavirus machupoense), which is transmitted_by vesper mouse, Calomys callosus. The infection has_symptom fever, has_symptom headache, has_symptom fatigue, has_symptom myalgia, has_symptom arthralgia, has_symptom bleeding from the oral and nasal mucosa, and has_symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary tracts.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/eid/vol1no3/kilgore.htm

Venezuelan hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Guanarito virus (Mammarenavirus guanaritoense), which is transmitted_by cotton rat, Sigmodon alstoni or transmitted_by cane mouse, Zygodontomys brevicauda. The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom sore throat, has_symptom weakness, has_symptom anorexia, has_symptom nausea, has_symptom vomiting, has_symptom convulsions, has_symptom epistaxis, has_symptom bleeding gums, has_symptom hematemesis, has_symptom melena, and has_symptom menorrhagia.
has db xref: ORDO:319234
has OBO namespace: disease_ontology
id: DOID:0050196
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: Venezuelan hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Guanarito virus (Mammarenavirus guanaritoense), which is transmitted_by cotton rat, Sigmodon alstoni or transmitted_by cane mouse, Zygodontomys brevicauda. The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom sore throat, has_symptom weakness, has_symptom anorexia, has_symptom nausea, has_symptom vomiting, has_symptom convulsions, has_symptom epistaxis, has_symptom bleeding gums, has_symptom hematemesis, has_symptom melena, and has_symptom menorrhagia.
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/34917387/
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/7840443/

Brazilian hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Sabia virus (Mammarenavirus brazilense), which is transmitted by rodents. The infection has symptom fever, has symptom eye redness, has symptom fatigue, has symptom dizziness, has symptom muscle aches, has symptom loss of strength, and has symptom bleeding under the skin, internal organs, or from body orifices like the mouth, eyes or ears.
has OBO namespace: disease_ontology
id: DOID:0050197
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Brazilian hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Sabia virus (Mammarenavirus brazilense), which is transmitted by rodents. The infection has symptom fever, has symptom eye redness, has symptom fatigue, has symptom dizziness, has symptom muscle aches, has symptom loss of strength, and has symptom bleeding under the skin, internal organs, or from body orifices like the mouth, eyes or ears.
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Brazilian_hemorrhagic_fever
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/18421377
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/7905555

Chapare hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Chapare virus (Mammarenavirus chapareense). The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom shock, and has symptom bleeding.
has OBO namespace: disease_ontology
id: DOID:0050198
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Chapare hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Chapare virus (Mammarenavirus chapareense). The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom shock, and has symptom bleeding.
type: ECO_0007645
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/18421377

Whitewater Arroyo hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Whitewater Arroyo virus (Mammarenavirus whitewaterense), which is transmitted_by white-throated woodrats (Neotoma albigula). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, and has_symptom hemorrhagic manifestations.
has OBO namespace: disease_ontology
id: DOID:0050199
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Whitewater Arroyo hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Whitewater Arroyo virus (Mammarenavirus whitewaterense), which is transmitted_by white-throated woodrats (Neotoma albigula). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, and has_symptom hemorrhagic manifestations.
type: ECO_0007645
has db xref: url:http://jama.ama-assn.org/cgi/content/full/284/10/1237
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/1799746

Korean hemorrhagic fever
type: Class
subclass of: Hantavirus hemorrhagic fever with renal syndrome
IAO_0000115: A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload.
has OBO namespace: disease_ontology
id: DOID:0050200
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Korean hemorrhagic fever
annotated property: IAO_0000115
annotated target: A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.cdc.gov/mmwr/preview/mmwrhtml/00051521.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/1349231

nephropathia epidemica
type: Class
subclass of: Hantavirus hemorrhagic fever with renal syndrome
IAO_0000115: A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Orthohantavirus puumalaense, which is transmitted_by bank vole, Myodes glareolus. The infection has_symptom headache, has_symptom nausea, has_symptom back pain, has_symptom vomiting, has_symptom myalgia, has_symptom abdominal pain, has_symptom internal hemorrhage, and has_symptom renal failure.
has OBO namespace: disease_ontology
id: DOID:0050201
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: nephropathia epidemica
annotated property: IAO_0000115
annotated target: A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Orthohantavirus puumalaense, which is transmitted_by bank vole, Myodes glareolus. The infection has_symptom headache, has_symptom nausea, has_symptom back pain, has_symptom vomiting, has_symptom myalgia, has_symptom abdominal pain, has_symptom internal hemorrhage, and has_symptom renal failure.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/1349231
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/2574903
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/2902106

Lujo hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that results_in infection, has_material_basis_in Lujo virus (Mammarenavirus lujoense), which has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom thrombocytopenia, and has_symptom bleeding. Bleeding is minor and not a prominent symptom.
has db xref: GARD:21410
has db xref: ICD10CM:A96.8
has db xref: MESH:C000723471
has db xref: ORDO:319213
has db xref: SNOMEDCT_US_2025_05_01:716585008
has db xref: UMLS_CUI:C4274433
has OBO namespace: disease_ontology
id: DOID:0050202
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease
broad match: ICD10CM:A96.8

Axiom
annotated source: Lujo hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, has_material_basis_in Lujo virus (Mammarenavirus lujoense), which has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom thrombocytopenia, and has_symptom bleeding. Bleeding is minor and not a prominent symptom.
type: ECO_0007645
has db xref: url:https://en.wikipedia.org/wiki/Lujo_virus
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC2866397/
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC4230886/
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/19478873/
has db xref: url:https://www.cdc.gov/lujo-fever/about/index.html

obsolete yellow fever hepatitis
type: Class
IAO_0000115: A Yellow fever virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Yellow fever virus. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, has_symptom weakness, has_symptom nausea, has_symptom vomiting, has_symptom jaundice, and has_symptom hemorrhagic manifestations.
has OBO namespace: disease_ontology
id: DOID:0050208
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete yellow fever hepatitis
annotated property: IAO_0000115
annotated target: A Yellow fever virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Yellow fever virus. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, has_symptom weakness, has_symptom nausea, has_symptom vomiting, has_symptom jaundice, and has_symptom hemorrhagic manifestations.
has db xref: url:http://books.google.com/books?id=739MM_WTJREC&pg=PA274&lpg#v=onepage&q=rubulavirus&f=false

swine influenza
type: Class
IAO_0000115: An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus (Gammainfluenzavirus influenzae), or has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae) including subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.
has OBO namespace: disease_ontology
id: DOID:0050211
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: swine influenza
annotated property: IAO_0000115
annotated target: An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus (Gammainfluenzavirus influenzae), or has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae) including subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.
type: ECO_0007637
type: ECO_0007645
has db xref: url:https://www.cdc.gov/swine-flu/about/index.html
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/9140195

obsolete Campylobacter jejuni gastroenteritis
type: Class
IAO_0000115: A primary Campylobacter infectious disease that involves inflammation of the stomach and intestines caused by Campylobacter jejuni infection, which is characterized by diarrhea (may be bloody), abdominal pain, fever and vomiting.
has exact synonym: Campylobacter Gastroenteritis
has OBO namespace: disease_ontology
id: DOID:0050212
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Campylobacter jejuni gastroenteritis
annotated property: IAO_0000115
annotated target: A primary Campylobacter infectious disease that involves inflammation of the stomach and intestines caused by Campylobacter jejuni infection, which is characterized by diarrhea (may be bloody), abdominal pain, fever and vomiting.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/17846438

obsolete Coxiella burnetii pneumonia
type: Class
IAO_0000115: A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission.
has exact synonym: Q fever pneumonia
has OBO namespace: disease_ontology
id: DOID:0050220
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Coxiella burnetii pneumonia
annotated property: IAO_0000115
annotated target: A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission.
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Q_fever
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/15021054

obsolete Coxiella burnetii hepatitis
type: Class
IAO_0000115: A Q fever that involves inflammation of the liver caused by Coxiella burnetti, which results in the formation of granulomas. The symptoms include fever, malaise, hepatomegaly with right upper abdominal pain, and jaundice.
has exact synonym: Q fever hepatitis
has OBO namespace: disease_ontology
id: DOID:0050221
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Coxiella burnetii hepatitis
annotated property: IAO_0000115
annotated target: A Q fever that involves inflammation of the liver caused by Coxiella burnetti, which results in the formation of granulomas. The symptoms include fever, malaise, hepatomegaly with right upper abdominal pain, and jaundice.
type: ECO_0007637
has db xref: url:http://www.merck.com/mmpe/sec14/ch177/ch177i.html

obsolete Brugia timori filariasis
type: Class
IAO_0000115: A filarial elephantiasis that involves parasitic infection by the nematode Brugia timori, which inhabits the lymphatics. The symptoms include fever and chronic lymphedema.
has OBO namespace: disease_ontology
id: DOID:0050249
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Brugia timori filariasis
annotated property: IAO_0000115
annotated target: A filarial elephantiasis that involves parasitic infection by the nematode Brugia timori, which inhabits the lymphatics. The symptoms include fever and chronic lymphedema.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Brugia_timori

Alkhumra hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Alkhurma hemorrhagic fever virus (Orthoflavivirus kyasanurense), which is transmitted by Ornithodoros savignyi tick bite, transmitted by ingestion of unpasteurized camel milk, or transmitted by entry via skin wound. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom thrombocytopenia, and has symptom hemorrhagic fever.
has exact synonym: Alkhurma hemorrhagic fever
has OBO namespace: disease_ontology
id: DOID:0050308
in subset: DO infectious disease slim
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Alkhumra hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Alkhurma hemorrhagic fever virus (Orthoflavivirus kyasanurense), which is transmitted by Ornithodoros savignyi tick bite, transmitted by ingestion of unpasteurized camel milk, or transmitted by entry via skin wound. The infection has symptom headache, has symptom joint pain, has symptom muscle pain, has symptom vomiting, has symptom thrombocytopenia, and has symptom hemorrhagic fever.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Alkhurma_virus
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650908/
has db xref: url:https://www.cdc.gov/alkhurma/about/

obsolete Capnocytophaga canimorsus infectious disease
type: Class
has OBO namespace: disease_ontology
id: DOID:0050363
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Campylobacter coli infectious disease
type: Class
has OBO namespace: disease_ontology
id: DOID:0050380
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Capnocytophaga canimorsus meningitis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050389
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Capnocytophaga canimorsus endocarditis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050390
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Yersinia pseudotuberculosis mesenteric lymphadenitis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050406
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Streptococcus zooepidemicus meningitis
type: Class
has exact synonym: Streptococcus equi subsp. zooepidemicus meningitis
has OBO namespace: disease_ontology
id: DOID:0050418
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Yersinia pseudotuberculosis gastroenteritis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050422
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

epidemic typhus
type: Class
subclass of: typhus
IAO_0000115: A typhus that has_material_basis_in Rickettsia prowazekii, which is transmitted by human body louse (Pediculus humanus corporis). The infection has_symptom high fever, has_symptom cough, has_symptom rash, has_symptom severe muscle pain, has_symptom chills, has_symptom falling blood pressure, has_symptom stupor, has_symptom sensitivity to light, and has_symptom delirium.
has exact synonym: sylvatic typhus
has OBO namespace: disease_ontology
id: DOID:0050480
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: epidemic typhus
annotated property: IAO_0000115
annotated target: A typhus that has_material_basis_in Rickettsia prowazekii, which is transmitted by human body louse (Pediculus humanus corporis). The infection has_symptom high fever, has_symptom cough, has_symptom rash, has_symptom severe muscle pain, has_symptom chills, has_symptom falling blood pressure, has_symptom stupor, has_symptom sensitivity to light, and has_symptom delirium.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Epidemic_typhus

endemic typhus
type: Class
subclass of: typhus
IAO_0000115: A typhus that has_material_basis_in Rickettsia typhi or has_material_basis_in Rickettsia felis, which are transmitted by fleas (Xenopsylla cheopis). The infection has symptom headache, has symptom fever, has symptom chills, has symptom myalgia, has symptom nausea, has symptom vomiting, has symptom cough and has symptom rash.
has alternative id: DOID:0050028
has alternative id: DOID:0050029
has alternative id: DOID:0050030
has alternative id: DOID:0050057
has alternative id: DOID:0050058
has exact synonym: Rat-Flea Typhus
has exact synonym: Rickettsia felis spotted fever
has exact synonym: Urban Typhus of Malaya
has exact synonym: cat flea rickettsiosis
has exact synonym: fleaborne typhus
has exact synonym: murine typhus
has exact synonym: toulon typhus
has exact synonym: urban typhus
has OBO namespace: disease_ontology
has related synonym: Shop typhus
id: DOID:0050481
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: endemic typhus
annotated property: IAO_0000115
annotated target: A typhus that has_material_basis_in Rickettsia typhi or has_material_basis_in Rickettsia felis, which are transmitted by fleas (Xenopsylla cheopis). The infection has symptom headache, has symptom fever, has symptom chills, has symptom myalgia, has symptom nausea, has symptom vomiting, has symptom cough and has symptom rash.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Murine_typhus

obsolete lymphangitis-associated rickettsiosis
type: Class
has OBO namespace: disease_ontology
id: DOID:0050482
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease
deprecated: true

aneruptive fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia helvetica, which is transmitted_by ticks (Ixodes sp). The infection has_symptom fever, has_symptom headache, has_symptom myalgia.
has exact synonym: Rickettsia helvetica spotted fever
has OBO namespace: disease_ontology
id: DOID:0050484
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: aneruptive fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia helvetica, which is transmitted_by ticks (Ixodes sp). The infection has_symptom fever, has_symptom headache, has_symptom myalgia.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://jcm.asm.org/cgi/reprint/42/2/816
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

sennetsu fever
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia.
has db xref: GARD:120
has db xref: MESH:C537582
has exact synonym: Sennetsu ehrlichiosis
has OBO namespace: disease_ontology
id: DOID:0050485
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: sennetsu fever
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia.
has db xref: url:https://rarediseases.org/rare-diseases/sennetsu-fever/

Barmah Forest virus disease
type: Class
IAO_0000115: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Barmah Forest virus (Alphavirus barmah), which is transmitted_by mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
has OBO namespace: disease_ontology
id: DOID:0050517
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Barmah Forest virus disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Barmah Forest virus (Alphavirus barmah), which is transmitted_by mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
has db xref: url:https://en.wikipedia.org/wiki/Barmah_Forest_virus
has db xref: url:https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/barmah-forest-virus-disease

Ross River fever
type: Class
IAO_0000115: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Ross River virus (Alphavirus rossriver), which is transmitted_by Culex, and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
has exact synonym: Ross River virus disease
has OBO namespace: disease_ontology
id: DOID:0050518
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Ross River fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection located_in joint, has_material_basis_in Ross River virus (Alphavirus rossriver), which is transmitted_by Culex, and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Ross_River_fever
has db xref: url:https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/ross-river-virus-disease

Oropouche fever
type: Class
IAO_0000115: A viral infectious disease that results in infection, has_material_basis_in Oropouche virus (Orthobunyavirus oropoucheense), which is transmitted by biting midge, Culicoides paraensis. The infection has symptom fever, has symptom chills, has symptom headache, has symptom anorexia, has symptom muscle pain, has symptom joint pain, and has symptom vomiting.
has db xref: ICD10CM:A93.0
has db xref: UMLS_CUI:C0276386
has OBO namespace: disease_ontology
id: DOID:0050521
in subset: DO infectious disease slim
in subset: zoonotic infectious disease
broad match: ICD9CM:066.3
broad match: MESH:D002044

Axiom
annotated source: Oropouche fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection, has_material_basis_in Oropouche virus (Orthobunyavirus oropoucheense), which is transmitted by biting midge, Culicoides paraensis. The infection has symptom fever, has symptom chills, has symptom headache, has symptom anorexia, has symptom muscle pain, has symptom joint pain, and has symptom vomiting.
type: ECO_0007637
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Oropouche_fever
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC5923469/
has db xref: url:https://wwwnc.cdc.gov/eid/article/13/6/06-1114_article

Balkan hemorrhagic fever
type: Class
subclass of: Hantavirus hemorrhagic fever with renal syndrome
IAO_0000115: A hemorrhagic fever with renal syndrome that results in infection located in kidney, has_material_basis_in Dobrava-Belgrade virus (Orthohantavirus dobravaense), which is transmitted by yellow-necked field mouse, Apodemus flavicollis. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure.
has OBO namespace: disease_ontology
id: DOID:0050522
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Balkan hemorrhagic fever
annotated property: IAO_0000115
annotated target: A hemorrhagic fever with renal syndrome that results in infection located in kidney, has_material_basis_in Dobrava-Belgrade virus (Orthohantavirus dobravaense), which is transmitted by yellow-necked field mouse, Apodemus flavicollis. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Dobrava-Belgrade_orthohantavirus
has db xref: url:https://en.wikipedia.org/wiki/Hantavirus_hemorrhagic_fever_with_renal_syndrome

sleeping sickness
type: Class
IAO_0000115: A trypanosomiasis that results from infection by Trypanosoma brucei and gambiense, which is transmitted by the bite of an infected tsetse fly (Glossina spp). The symptoms include fever, headache, joint pain, itching, confusion, sensory disturbances, poor coordination and sleep disturbances.
has db xref: GARD:7826
has db xref: ICD10CM:B56
has db xref: ICD9CM:086.5
has db xref: KEGG:05143
has db xref: MESH:D014353
has db xref: NCI:C84541
has db xref: ORDO:3385
has db xref: SNOMEDCT_US_2023_03_01:27031003
has db xref: UMLS_CUI:C0041228
has exact synonym: African sleeping sickness
has exact synonym: African trypanosomiasis
has OBO namespace: disease_ontology
id: DOID:10112
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: sleeping sickness
annotated property: IAO_0000115
annotated target: A trypanosomiasis that results from infection by Trypanosoma brucei and gambiense, which is transmitted by the bite of an infected tsetse fly (Glossina spp). The symptoms include fever, headache, joint pain, itching, confusion, sensory disturbances, poor coordination and sleep disturbances.
type: ECO_0007637
type: ECO_0007638
type: ECO_0007640
has db xref: url:http://en.wikipedia.org/wiki/African_trypanosomiasis
has db xref: url:http://www.nlm.nih.gov/medlineplus/ency/article/001362.htm
has db xref: url:http://www.who.int/mediacentre/factsheets/fs259/en/

obsolete Trypanosoma brucei rhodesiense infectious disease
type: Class
IAO_0000115: A sleeping sickness that involves infection caused by Trypanosoma brucei rhodesiense, which is carried by the tsetse fly. The symptoms include fever, severe headache, irritability, extreme fatigue, swollen lymph nodes, aching muscles and joints, skin rash, progressive confusion, personality changes, and other neurologic problems.
has exact synonym: East African trypanosomiasis
has exact synonym: Rhodesian sleeping sickness
has exact synonym: Rhodesian trypanosomiasis
has exact synonym: trypanosoma rhodesiense infectious disease
has OBO namespace: disease_ontology
id: DOID:10114
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Trypanosoma brucei rhodesiense infectious disease
annotated property: IAO_0000115
annotated target: A sleeping sickness that involves infection caused by Trypanosoma brucei rhodesiense, which is carried by the tsetse fly. The symptoms include fever, severe headache, irritability, extreme fatigue, swollen lymph nodes, aching muscles and joints, skin rash, progressive confusion, personality changes, and other neurologic problems.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dpd/parasites/trypanosomiasis/factsht_ea_trypanosomiasis.htm

obsolete Trypanosoma brucei gambiense infectious disease
type: Class
IAO_0000115: A sleeping sickness that involves infection caused by Trypanosoma brucei gambiense, which is carried by the tsetse fly. The symptoms include fever, rash, swelling of the face and hands, headaches, fatigue, aching muscles and joints, itching skin, swollen lymph nodes, progressive confusion, personality changes, daytime sleepiness with nighttime sleep disturbances, and other neurologic problems.
has exact synonym: Gambian Trypanosomiasis
has exact synonym: Gambian sleeping sickness
has exact synonym: West African trypanosomiasis
has OBO namespace: disease_ontology
id: DOID:10116
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Trypanosoma brucei gambiense infectious disease
annotated property: IAO_0000115
annotated target: A sleeping sickness that involves infection caused by Trypanosoma brucei gambiense, which is carried by the tsetse fly. The symptoms include fever, rash, swelling of the face and hands, headaches, fatigue, aching muscles and joints, itching skin, swollen lymph nodes, progressive confusion, personality changes, daytime sleepiness with nighttime sleep disturbances, and other neurologic problems.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dpd/parasites/trypanosomiasis/factsht_wa_trypanosomiasis.htm

pneumonic plague
type: Class
subclass of: plague
IAO_0000115: A plague that results_in infection located_in lung, which results from direct inhalation of the bacillus and has_symptom fever, has_symptom chills, has_symptom cough and has_symptom difficulty breathing.
has alternative id: DOID:10401
has alternative id: DOID:10402
has db xref: ICD10CM:A20.2
has db xref: ICD9CM:020.3
has db xref: ICD9CM:020.4
has db xref: ICD9CM:020.5
has db xref: MESH:D010930
has db xref: SNOMEDCT_US_2023_03_01:35339003
has db xref: SNOMEDCT_US_2023_03_01:38976008
has db xref: SNOMEDCT_US_2023_03_01:67525007
has db xref: UMLS_CUI:C0152937
has db xref: UMLS_CUI:C0152938
has db xref: UMLS_CUI:C0524688
has exact synonym: primary pneumonic plague
has exact synonym: secondary pneumonic plague
has OBO namespace: disease_ontology
id: DOID:10398
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: pneumonic plague
annotated property: IAO_0000115
annotated target: A plague that results_in infection located_in lung, which results from direct inhalation of the bacillus and has_symptom fever, has_symptom chills, has_symptom cough and has_symptom difficulty breathing.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Pneumonic_plague

obsolete Bacillus anthracis pneumonia
type: Class
IAO_0000115: A primary Bacillaceae infectious disease involving Bacillus anthracis infection resulting in pulmonary infiltrates and necrosis.
has exact synonym: Anthrax pneumonia (disorder)
has exact synonym: Pneumonia in anthrax
has exact synonym: Woolsorters' pneumonia
has OBO namespace: disease_ontology
id: DOID:10508
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Bacillus anthracis pneumonia
annotated property: IAO_0000115
annotated target: A primary Bacillaceae infectious disease involving Bacillus anthracis infection resulting in pulmonary infiltrates and necrosis.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.cdc.gov/ncidod/EID/vol7no6/jernigan.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/8460135

bubonic plague
type: Class
subclass of: plague
IAO_0000115: A plague that results_in infection located_in lymph node producing a bubo, which is an inflamed, necrotic, and hemorrhagic lymphoid tissue. The infection has_symptom enlarged, tender lymph nodes, has_symptom fever, has_symptom chills and has_symptom prostration.
has alternative id: DOID:0050068
has db xref: GARD:183
has db xref: ICD10CM:A20.0
has db xref: ICD9CM:020.0
has db xref: MESH:D010930
has db xref: SNOMEDCT_US_2023_03_01:50797007
has db xref: UMLS_CUI:C0282312
has exact synonym: black death
has OBO namespace: disease_ontology
id: DOID:10773
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: bubonic plague
annotated property: IAO_0000115
annotated target: A plague that results_in infection located_in lymph node producing a bubo, which is an inflamed, necrotic, and hemorrhagic lymphoid tissue. The infection has_symptom enlarged, tender lymph nodes, has_symptom fever, has_symptom chills and has_symptom prostration.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Bubonic_plague

obsolete cutaneous plague
type: Class
has exact synonym: cellulocutaneous plague
has exact synonym: cellulocutaneous plague (disorder)
has OBO namespace: disease_ontology
id: DOID:10774
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Queensland tick typhus
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia australis, which is transmitted_by ticks (Ixodes holocyclus). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom maculopapular rash, and has_symptom lymphadenopathy.
has alternative id: DOID:0050038
has exact synonym: Australian tick typhus
has exact synonym: Rickettsia australis spotted fever
has OBO namespace: disease_ontology
has related synonym: North Queensland tick typhus
id: DOID:10784
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Queensland tick typhus
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia australis, which is transmitted_by ticks (Ixodes holocyclus). The infection has_symptom fever, has_symptom headache, has_symptom myalgia, has_symptom maculopapular rash, and has_symptom lymphadenopathy.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://cmr.asm.org/cgi/content/full/18/4/719#Rickettsia_australis_%28Queensland_tick_typhus%29
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

setariasis
type: Class
IAO_0000115: A filariasis that involves parasitic infection of the abdomen in cattle, horses and sheep by nematodes of the genus Setaria.
has db xref: MESH:D012719
has db xref: SNOMEDCT_US_2023_03_01:4414005
has db xref: UMLS_CUI:C0036850
has exact synonym: Infectious Disease by Setaria
has OBO namespace: disease_ontology
id: DOID:1079
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: setariasis
annotated property: IAO_0000115
annotated target: A filariasis that involves parasitic infection of the abdomen in cattle, horses and sheep by nematodes of the genus Setaria.
type: ECO_0007645
has db xref: url:http://www.jstor.org/stable/pdfplus/3277411.pdf

obsolete leptospiral meningitis
type: Class
has exact synonym: Aseptic leptospiral meningitis
has exact synonym: Aseptic leptospiral meningitis (disorder)
has exact synonym: Leptospiral meningitis (aseptic)
has exact synonym: Leptospiral meningitis (disorder)
has OBO namespace: disease_ontology
id: DOID:10818
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

dirofilariasis
type: Class
IAO_0000115: A filariasis that is a zoonotic infection caused by nematodes Dirofilaria immitis or Dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. The disease manifests as either subcutaneous nodules or pulmonary lesions.
has db xref: GARD:11908
has db xref: ICD10CM:B74.8
has db xref: MESH:D004184
has db xref: SNOMEDCT_US_2023_03_01:73328005
has db xref: UMLS_CUI:C0012602
has exact synonym: Dirofilaria infectious disease
has exact synonym: Infection by Dirofilaria
has OBO namespace: disease_ontology
id: DOID:1082
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: dirofilariasis
annotated property: IAO_0000115
annotated target: A filariasis that is a zoonotic infection caused by nematodes Dirofilaria immitis or Dirofilaria repens, which are transmitted to humans from dogs, cats, wolves and coyotes by infected mosquitoes. The disease manifests as either subcutaneous nodules or pulmonary lesions.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Dirofilariasis

Eastern equine encephalitis
type: Class
IAO_0000115: A viral infectious disease that results in inflammation located in brain of horses and humans, has_material_basis_in Eastern equine encephalitis virus (Alphavirus eastern), which is transmitted by Aedes, transmitted by Coquillettidia, and transmitted by Culex species of mosquitoes. The infection has symptom sudden onset of headache, has symptom high fever, has symptom chills, has symptom vomiting, has symptom disorientation, has symptom seizures, and has symptom coma.
has db xref: GARD:10821
has db xref: ICD10CM:A83.2
has db xref: ICD9CM:062.2
has db xref: MESH:D020242
has db xref: ORDO:83594
has db xref: SNOMEDCT_US_2025_05_01:416925005
has db xref: UMLS_CUI:C0153065
has exact synonym: Neuroinvasive Eastern equine encephalitis virus infection
has OBO namespace: disease_ontology
has related synonym: EEE
id: DOID:10841
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: Eastern equine encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in inflammation located in brain of horses and humans, has_material_basis_in Eastern equine encephalitis virus (Alphavirus eastern), which is transmitted by Aedes, transmitted by Coquillettidia, and transmitted by Culex species of mosquitoes. The infection has symptom sudden onset of headache, has symptom high fever, has symptom chills, has symptom vomiting, has symptom disorientation, has symptom seizures, and has symptom coma.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/EasternEquineEncephalitis/index.html
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK557692/

Axiom
annotated source: Eastern equine encephalitis
annotated property: hasRelatedSynonym
annotated target: EEE
has synonym type: OMO_0003012

Western equine encephalitis
type: Class
IAO_0000115: A viral infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Western equine encephalomyelitis virus (Alphavirus western), which is transmitted_by Culex and transmitted_by Aedes species of mosquitoes. The infection has_symptom fever, has_symptom headache, has_symptom nausea, has_symptom vomiting, has_symptom anorexia, has_symptom malaise, has_symptom altered mental status, and has_symptom weakness.
has db xref: GARD:7888
has db xref: ICD10CM:A83.1
has db xref: ICD9CM:062.1
has db xref: MESH:D020241
has db xref: NCI:C85227
has db xref: SNOMEDCT_US_2023_03_01:47523006
has db xref: UMLS_CUI:C0153064
has OBO namespace: disease_ontology
has related synonym: WEE
id: DOID:10843
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Western equine encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Western equine encephalomyelitis virus (Alphavirus western), which is transmitted_by Culex and transmitted_by Aedes species of mosquitoes. The infection has_symptom fever, has_symptom headache, has_symptom nausea, has_symptom vomiting, has_symptom anorexia, has_symptom malaise, has_symptom altered mental status, and has_symptom weakness.
type: ECO_0007637
has db xref: url:https://www.cdc.gov/wee/about/
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK470228/

Axiom
annotated source: Western equine encephalitis
annotated property: hasRelatedSynonym
annotated target: WEE
has synonym type: OMO_0003012

Siberian tick typhus
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia sibirica, which is transmitted_by ticks (Dermacentor nuttalli, Dermacentor marginatus and Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash.
has alternative id: DOID:0050054
has alternative id: DOID:0050055
has db xref: ICD10CM:A77.2
has db xref: ICD9CM:082.2
has db xref: MESH:D000073605
has db xref: SNOMEDCT_US_2023_03_01:7692008
has db xref: UMLS_CUI:C0549160
has exact synonym: North Asian tick fever
has exact synonym: North Asian tick typhus
has exact synonym: Rickettsia sibirica spotted fever
has exact synonym: manchurian typhus
has OBO namespace: disease_ontology
id: DOID:10921
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Siberian tick typhus
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia sibirica, which is transmitted_by ticks (Dermacentor nuttalli, Dermacentor marginatus and Haemaphysalis concinna). The infection has_symptom fever, has_symptom eschar, has_symptom regional adenopathy, and has_symptom maculopapular rash.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://cmr.asm.org/cgi/content/full/18/4/719#%27%27Rickettsia_sibirica_subsp._sibirica%27%27_%28Siberian_tick_typhus_or_North_Asian_tick_typhus%29
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

obsolete Salmonella arizonae intestinal infectious disease
type: Class
IAO_0000115: A Salmonella infectious disease that involves infection of the intestine caused by Salmonella enterica subsp arizonae, which is a gut inhabitant of reptiles. The symptoms include fever, headache, abdominal pain, vomiting, and diarrhea.
has exact synonym: intestinal infectious disease due to arizona group of paracolon bacilli
has OBO namespace: disease_ontology
id: DOID:10958
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Salmonella arizonae intestinal infectious disease
annotated property: IAO_0000115
annotated target: A Salmonella infectious disease that involves infection of the intestine caused by Salmonella enterica subsp arizonae, which is a gut inhabitant of reptiles. The symptoms include fever, headache, abdominal pain, vomiting, and diarrhea.
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/14662995

pasteurellosis
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Pasteurella multocida, which is transmitted_by animal bite, scratch, or lick. The infection has_symptom joint pain has_symptom fever, has_symptom rigors, has_symptom pneumonia, has_symptom meningeal irritation, and has_symptom tachycardia.
has db xref: ICD10CM:A28.0
has db xref: ICD9CM:027.2
has db xref: MESH:D010326
has db xref: SNOMEDCT_US_2023_03_01:276199008
has db xref: UMLS_CUI:C0030636
has exact synonym: Pasteurella infection
has exact synonym: Pasteurella infectious disease
has OBO namespace: disease_ontology
id: DOID:11055
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: pasteurellosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Pasteurella multocida, which is transmitted_by animal bite, scratch, or lick. The infection has_symptom joint pain has_symptom fever, has_symptom rigors, has_symptom pneumonia, has_symptom meningeal irritation, and has_symptom tachycardia.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Pasteurellosis

obsolete Pasteurella hemorrhagic septicemia
type: Class
has exact synonym: hemorrhagic septicemia
has OBO namespace: disease_ontology
id: DOID:11056
in subset: GOLD
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Brucella suis brucellosis
type: Class
subclass of: brucellosis
IAO_0000115: A brucellosis that involves an infection caused by Brucella suis in swine and humans. The disease has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom diaphoresis, has_symptom arthralgia, has_symptom myalgia, has_symptom headache, has_symptom anorexia, and has_symptom fatigue.
has OBO namespace: disease_ontology
id: DOID:11076
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Brucella suis brucellosis
annotated property: IAO_0000115
annotated target: A brucellosis that involves an infection caused by Brucella suis in swine and humans. The disease has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom diaphoresis, has_symptom arthralgia, has_symptom myalgia, has_symptom headache, has_symptom anorexia, and has_symptom fatigue.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5822a3.htm

brucellosis
type: Class
IAO_0000115: A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue.
has alternative id: DOID:0050060
has db xref: GARD:5966
has db xref: ICD10CM:A23
has db xref: ICD9CM:023
has db xref: MESH:D002006
has db xref: NCI:C84602
has db xref: SNOMEDCT_US_2023_03_01:154296006
has db xref: UMLS_CUI:C0006309
has exact synonym: Maltese fever
has exact synonym: undulant fever
has OBO namespace: disease_ontology
has related synonym: Bang's disease
has related synonym: Gibraltar fever
has related synonym: Malta fever
has related synonym: Mediterranean fever
id: DOID:11077
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: brucellosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dbmd/diseaseinfo/Brucellosis_g.htm

obsolete Salmonella gastroenteritis
type: Class
IAO_0000115: A Salmonella infectious disease that involves inflammation of the stomach and intestines caused by Salmonella infection. The symptoms include diarrhea, vomiting, abdominal pain, fever and weakness.
has exact synonym: Enteric paratyphosis
has exact synonym: Salmonella food poisoning
has exact synonym: Salmonella food poisoning (disorder)
has exact synonym: Salmonella gastroenteritis
has exact synonym: Salmonella gastroenteritis (disorder)
has exact synonym: Salmonella gastroenteritis [Ambiguous]
has exact synonym: Salmonellosis
has exact synonym: Salmonellosis (& [gastroenteritis] or [food poisoning])
has OBO namespace: disease_ontology
id: DOID:11092
in subset: GOLD
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Salmonella gastroenteritis
annotated property: IAO_0000115
annotated target: A Salmonella infectious disease that involves inflammation of the stomach and intestines caused by Salmonella infection. The symptoms include diarrhea, vomiting, abdominal pain, fever and weakness.
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/12631900

Q fever
type: Class
IAO_0000115: A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia.
has db xref: GARD:7515
has db xref: ICD10CM:A78
has db xref: ICD9CM:083.0
has db xref: MESH:D011778
has db xref: NCI:C34970
has db xref: SNOMEDCT_US_2023_03_01:266205000
has db xref: UMLS_CUI:C0034362
has exact synonym: Infection due to Coxiella burnetii
has OBO namespace: disease_ontology
id: DOID:11100
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Q fever
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia.
type: ECO_0007637
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Q_fever
has db xref: url:http://www.cdc.gov/qfever/symptoms/index.html
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/15021054

rickettsialpox
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia akari, which is transmitted_by house mouse mite (Liponyssoides sanguineus) found on mice and other rodents. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, and has_symptom papulovesicular rash.
has alternative id: DOID:0050037
has db xref: ICD10CM:A79.1
has db xref: ICD9CM:083.2
has db xref: MESH:D000073605
has db xref: SNOMEDCT_US_2023_03_01:75096007
has db xref: UMLS_CUI:C0035597
has exact synonym: Rickettsia akari spotted fever
has exact synonym: Vesicular rickettsiosis
has OBO namespace: disease_ontology
id: DOID:11103
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: rickettsialpox
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia akari, which is transmitted_by house mouse mite (Liponyssoides sanguineus) found on mice and other rodents. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, and has_symptom papulovesicular rash.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

obsolete anthrax septicemia
type: Class
has exact synonym: Anthrax septicemia (disorder)
has OBO namespace: disease_ontology
id: DOID:11144
in subset: GOLD
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Brill-Zinsser disease
type: Class
subclass of: epidemic typhus
IAO_0000115: An epidemic typhus that is a mild form of the disease, which recurs in someone after a long period of latency due to immunosuppression, malnutrition or other illnesses.
has db xref: ICD10CM:A75.1
has db xref: ICD9CM:081.1
has db xref: MESH:D014438
has db xref: SNOMEDCT_US_2023_03_01:47761007
has db xref: UMLS_CUI:C0006181
has exact synonym: Brill Zinsser disease
has exact synonym: Brill's disease
has exact synonym: Recrudescent typhus
has OBO namespace: disease_ontology
has related synonym: Latent typhus
has related synonym: Sporadic typhus
id: DOID:11254
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Brill-Zinsser disease
annotated property: IAO_0000115
annotated target: An epidemic typhus that is a mild form of the disease, which recurs in someone after a long period of latency due to immunosuppression, malnutrition or other illnesses.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Epidemic_typhus

typhus
type: Class
IAO_0000115: A primary bacterial infectious disease that refers to a group of diseases, located in endothelial cells of the small venous, arterial, and capillary vessels, has_material_basis_in Rickettsia bacteria, which are transmitted by lice, transmitted by fleas, and transmitted by mites.
has alternative id: DOID:11255
has alternative id: DOID:12353
has db xref: GARD:7833
has db xref: ICD10CM:A75.0
has db xref: ICD10CM:A75.2
has db xref: ICD10CM:A75.9
has db xref: ICD9CM:080
has db xref: ICD9CM:081.0
has db xref: ICD9CM:081.9
has db xref: MESH:D014437
has db xref: MESH:D014438
has db xref: NCI:C84688
has db xref: NCI:C84689
has db xref: SNOMEDCT_US_2023_03_01:154375001
has db xref: SNOMEDCT_US_2023_03_01:25668000
has db xref: SNOMEDCT_US_2023_03_01:39111003
has db xref: UMLS_CUI:C0041471
has db xref: UMLS_CUI:C0041472
has db xref: UMLS_CUI:C0041473
has exact synonym: Endemic Typhus fever
has exact synonym: Exanthematic Typhus fever
has exact synonym: Flea typhus
has exact synonym: Louse-borne [epidemic] typhus
has exact synonym: Moscow typhus
has exact synonym: Murine [endemic] typhus
has exact synonym: Typhus fever
has exact synonym: endemic flea-borne typhus
has exact synonym: epidemic louse-borne typhus
has OBO namespace: disease_ontology
has related synonym: Classical typhus
has related synonym: Epidemic (louse-borne) typhus
has related synonym: Epidemic louse-borne typhus fever due to Rickettsia prowazekii
has related synonym: European typhus
has related synonym: Exanthematous typhus
has related synonym: Famine fever
has related synonym: Flea-borne rickettsiosis
has related synonym: Flea-borne typhus
has related synonym: Hospital fever
has related synonym: Jail fever
has related synonym: Louse-borne rickettsiosis
has related synonym: Louse-borne typhus
has related synonym: Mexican typhus
has related synonym: Murine typhus
has related synonym: Petechial fever
has related synonym: Prison fever
has related synonym: Rat flea typhus
has related synonym: Ship fever
has related synonym: Shop typhus
has related synonym: Typhus exanthematique
has related synonym: Urban typhus
id: DOID:11256
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: typhus
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that refers to a group of diseases, located in endothelial cells of the small venous, arterial, and capillary vessels, has_material_basis_in Rickettsia bacteria, which are transmitted by lice, transmitted by fleas, and transmitted by mites.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Typhus

cat-scratch disease
type: Class
IAO_0000115: A bartonellosis that results_in infection located_in lymph node, has_material_basis_in Bartonella henselae or has_material_basis_in Bartonella clarridgeiae, which are transmitted_by scratch or bite of a kitten, or transmitted_by contact of animal's saliva with an eye or through broken skin. The infection has_symptom regional lymphadenopathy, has_symptom headache, has_symptom chills, has_symptom backache, and has_symptom abdominal pain.
has db xref: ICD10CM:A28.1
has db xref: ICD9CM:078.3
has db xref: MESH:D002372
has db xref: NCI:C84620
has db xref: SNOMEDCT_US_2023_03_01:123319006
has db xref: UMLS_CUI:C0007361
has exact synonym: Debre's Syndrome
has exact synonym: Debre-Mollaret Syndrome
has exact synonym: Foshay-Mollaret Cat Scratch Fever
has exact synonym: benign lymphoreticulosis
has exact synonym: cat scratch fever
has OBO namespace: disease_ontology
id: DOID:11258
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: cat-scratch disease
annotated property: IAO_0000115
annotated target: A bartonellosis that results_in infection located_in lymph node, has_material_basis_in Bartonella henselae or has_material_basis_in Bartonella clarridgeiae, which are transmitted_by scratch or bite of a kitten, or transmitted_by contact of animal's saliva with an eye or through broken skin. The infection has_symptom regional lymphadenopathy, has_symptom headache, has_symptom chills, has_symptom backache, and has_symptom abdominal pain.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Cat_scratch_disease
has db xref: url:http://kidshealth.org/parent/infections/bacterial_viral/cat_scratch.html#

rabies
type: Class
IAO_0000115: A viral infectious disease that results in inflammation located in brain or located in spinal cord, has_material_basis_in viruses in the genus Lyssavirus, which are transmitted by bite of an infected animal, or transmitted by contact of mucous membranes with saliva of an infected animal. The infection has symptom fever, has symptom headache, has symptom prickling or itching sensation at the site of bite, has symptom anxiety, has symptom confusion, has symptom agitation, has symptom delirium, has symptom difficulty swallowing, has symptom hydrophobia, and has symptom paralysis. Most human cases of rabies are caused by the Rabies virus (Lyssavirus rabies) transmitted from dogs.
has db xref: GARD:7516
has db xref: ICD10CM:A82
has db xref: ICD9CM:071
has db xref: MESH:D011818
has db xref: NCI:C28182
has db xref: SNOMEDCT_US_2023_03_01:14168008
has db xref: UMLS_CUI:C0034494
has exact synonym: Lyssa
has OBO namespace: disease_ontology
id: DOID:11260
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: rabies
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in inflammation located in brain or located in spinal cord, has_material_basis_in viruses in the genus Lyssavirus, which are transmitted by bite of an infected animal, or transmitted by contact of mucous membranes with saliva of an infected animal. The infection has symptom fever, has symptom headache, has symptom prickling or itching sensation at the site of bite, has symptom anxiety, has symptom confusion, has symptom agitation, has symptom delirium, has symptom difficulty swallowing, has symptom hydrophobia, and has symptom paralysis. Most human cases of rabies are caused by the Rabies virus (Lyssavirus rabies) transmitted from dogs.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Rabies
has db xref: url:https://www.cdc.gov/yellow-book/hcp/travel-associated-infections-diseases/rabies.html

ornithosis
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Chlamydia psittaci, which is transmitted_by inhaling aerosolized dried droppings or transmitted_by contact with infected birds. The infection has_symptom fever, has_symptom headache, has_symptom rash, has_symptom chills, and has_symptom pneumonia.
has db xref: ICD10CM:A70
has db xref: ICD9CM:073
has db xref: MESH:D009956
has db xref: NCI:C34873
has db xref: SNOMEDCT_US_2023_03_01:154369005
has db xref: UMLS_CUI:C0029291
has exact synonym: psittacosis
has OBO namespace: disease_ontology
id: DOID:11262
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: ornithosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Chlamydia psittaci, which is transmitted_by inhaling aerosolized dried droppings or transmitted_by contact with infected birds. The infection has_symptom fever, has_symptom headache, has_symptom rash, has_symptom chills, and has_symptom pneumonia.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Psittacosis

Hantavirus hemorrhagic fever with renal syndrome
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Orthohantavirus dobravaense, Orthohantavirus hantanense, Orthohantavirus puumalaense, or Orthohantavirus seoulense, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure.
has db xref: GARD:18689
has db xref: ICD10CM:A98.5
has db xref: ICD9CM:078.6
has db xref: MESH:D006480
has db xref: NCI:C84753
has db xref: ORDO:340
has db xref: SNOMEDCT_US_2025_05_01:716864001
has db xref: UMLS_CUI:C0019101
has exact synonym: HFRS
has exact synonym: Hemorrhagic fever, Russian
has exact synonym: Hemorrhagic nephrosonephritis
has exact synonym: Puumala virus nephropathy
has exact synonym: hemorrhagic fever renal syndrome
has OBO namespace: disease_ontology
id: DOID:11266
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease
related match: MESH:C535630
related match: UMLS_CUI:C2930957

Axiom
annotated source: Hantavirus hemorrhagic fever with renal syndrome
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Orthohantavirus dobravaense, Orthohantavirus hantanense, Orthohantavirus puumalaense, or Orthohantavirus seoulense, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure.
type: ECO_0007637
type: ECO_0007645
has db xref: url:https://en.wikipedia.org/wiki/Hantavirus_hemorrhagic_fever_with_renal_syndrome
has db xref: url:https://www.cdc.gov/hantavirus/about/

Axiom
annotated source: Hantavirus hemorrhagic fever with renal syndrome
annotated property: hasExactSynonym
annotated target: HFRS
has synonym type: OMO_0003012

phlebotomus fever
type: Class
IAO_0000115: A viral infectious disease that results in infection, has_material_basis_in Sandfly fever Naples virus (Phlebovirus napoliense) or Sandfly fever sicilian virus (Phlebovirus siciliaense), which are transmitted by Phlebotomus papatasi sandfly. The infection has symptom fever, has symptom severe frontal headaches, has symptom muscle ache, has symptom joint aches, has symptom flushing of the face, and has symptom tachycardia.
has db xref: ICD10CM:A93.1
has db xref: ICD9CM:066.0
has db xref: MESH:D010217
has db xref: SNOMEDCT_US_2025_05_01:407476002
has db xref: UMLS_CUI:C0030372
has exact synonym: Sandfly fever
has exact synonym: Sandfly-borne arboviral fever
has exact synonym: Sandfly-borne bunyavirus fever
has exact synonym: Sandfly-borne phleboviral disease
has exact synonym: pappataci fever
has OBO namespace: disease_ontology
id: DOID:11360
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: phlebotomus fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection, has_material_basis_in Sandfly fever Naples virus (Phlebovirus napoliense) or Sandfly fever sicilian virus (Phlebovirus siciliaense), which are transmitted by Phlebotomus papatasi sandfly. The infection has symptom fever, has symptom severe frontal headaches, has symptom muscle ache, has symptom joint aches, has symptom flushing of the face, and has symptom tachycardia.
type: ECO_0007638
type: ECO_0007639
type: ECO_0007643
has db xref: url:http://en.wikipedia.org/wiki/Pappataci_fever
has db xref: url:https://www.britannica.com/science/pappataci-fever
has db xref: url:https://www.merriam-webster.com/dictionary/sandfly%20fever

Listeria meningitis
type: Class
IAO_0000115: A bacterial meningitis that has_material_basis_in Listeria monocytogenes infection.
has db xref: MESH:D008584
has db xref: SNOMEDCT_US_2023_03_01:230151007
has db xref: UMLS_CUI:C0025293
has OBO namespace: disease_ontology
id: DOID:11572
in subset: DO infectious disease slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Listeria meningitis
annotated property: IAO_0000115
annotated target: A bacterial meningitis that has_material_basis_in Listeria monocytogenes infection.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/21877182

listeriosis
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Listeria monocytogenes, which is transmitted_by ingestion of contaminated food or raw milk or transmitted_by congenital method. Ingestion of Listeria by pregnant women has_symptom nausea, has_symptom vomiting, has_symptom diarrhea, has_symptom fever, has_symptom malaise, has_symptom back pain, and has_symptom headache. Maternal infection with Listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.
has db xref: ICD10CM:A32
has db xref: ICD9CM:027.0
has db xref: MESH:D008088
has db xref: NCI:C82994
has db xref: SNOMEDCT_US_2023_03_01:186315001
has db xref: UMLS_CUI:C0023860
has exact synonym: Infection by Listeria monocytogenes
has exact synonym: Listeria infection
has OBO namespace: disease_ontology
id: DOID:11573
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: listeriosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Listeria monocytogenes, which is transmitted_by ingestion of contaminated food or raw milk or transmitted_by congenital method. Ingestion of Listeria by pregnant women has_symptom nausea, has_symptom vomiting, has_symptom diarrhea, has_symptom fever, has_symptom malaise, has_symptom back pain, and has_symptom headache. Maternal infection with Listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.
type: ECO_0007640
has db xref: url:http://www.nlm.nih.gov/medlineplus/ency/article/001380.htm

Lyme disease
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.
has alternative id: DOID:12233
has db xref: GARD:12073
has db xref: ICD10CM:A69.2
has db xref: ICD9CM:088.81
has db xref: MESH:D008193
has db xref: MESH:D020852
has db xref: NCI:C45161
has db xref: SNOMEDCT_US_2023_03_01:154376000
has db xref: SNOMEDCT_US_2023_03_01:715507005
has db xref: UMLS_CUI:C0024198
has db xref: UMLS_CUI:C0752235
has exact synonym: Bannwarth syndrome
has exact synonym: Bannworth's syndrome
has exact synonym: Lyme borreliosis
has exact synonym: Neurological Lyme disease
has exact synonym: lyme neuroborreliosis
has exact synonym: neuroborreliosis
has OBO namespace: disease_ontology
id: DOID:11729
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Lyme disease
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/lyme/transmission/index.html

Creutzfeldt-Jakob disease
type: Class
has db xref: EFO:0004226
has db xref: GARD:6956
has db xref: ICD10CM:A81.0
has db xref: ICD9CM:046.1
has db xref: MESH:D007562
has db xref: MIM:123400
has db xref: NCI:C26802
has db xref: SNOMEDCT_US_2023_03_01:155061007
has db xref: UMLS_CUI:C0022336
has exact synonym: CJD
has exact synonym: Creutzfeldt Jacob syndrome
has exact synonym: Creutzfeldt Jakob disease
has exact synonym: Creutzfeldt-Jacob disease
has exact synonym: Jakob-Creutzfeldt disease
has exact synonym: Subacute spongiform encephalopathy
has exact synonym: Transmissible virus dementia
has OBO namespace: disease_ontology
id: DOID:11949
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease
comment: OMIM mapping confirmed by DO. [SN].

Axiom
annotated source: Creutzfeldt-Jakob disease
annotated property: hasExactSynonym
annotated target: CJD
has synonym type: OMO_0003012

ulceroglandular tularemia
type: Class
subclass of: tularemia
IAO_0000115: A tularemia that results_in painful regional lymphadenopathy and an ulcerated skin lesion.
has db xref: ICD10CM:A21.0
has db xref: ICD9CM:021.0
has db xref: SNOMEDCT_US_2023_03_01:37722001
has db xref: UMLS_CUI:C0152941
has OBO namespace: disease_ontology
id: DOID:11990
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: ulceroglandular tularemia
annotated property: IAO_0000115
annotated target: A tularemia that results_in painful regional lymphadenopathy and an ulcerated skin lesion.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/tularemia/signssymptoms/

obsolete Trypanosoma meningitis
type: Class
IAO_0000115: A trypanosomiasis that involves inflammation of the meninges caused due to Trypanosoma species.
has exact synonym: Meningitis due to trypanosomiasis
has exact synonym: Trypanosomiasis with meningitis (disorder)
has exact synonym: trypanosomiasis with meningitis
has OBO namespace: disease_ontology
id: DOID:12054
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Trypanosoma meningitis
annotated property: IAO_0000115
annotated target: A trypanosomiasis that involves inflammation of the meninges caused due to Trypanosoma species.
type: ECO_0007645
has db xref: url:http://www.tropicalmedandhygienejrnl.net/article/0035-9203%2895%2990637-1/abstract

sodoku disease
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Spirillum minus, which is transmitted_by contact with urine or secretions from the mouth, eye, or nose of an infected animal or transmitted_by bite of an infected animal, especially rat. The infection has_symptom chills, has_symptom relapsing fever, has_symptom rash and has_symptom joint pain.
has db xref: ICD10CM:A25.0
has db xref: ICD9CM:026.0
has db xref: MESH:D011906
has db xref: SNOMEDCT_US_2023_03_01:19044004
has db xref: UMLS_CUI:C0152062
has exact synonym: Spirillary fever
has OBO namespace: disease_ontology
has related synonym: Spirillosis
id: DOID:12096
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: sodoku disease
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Spirillum minus, which is transmitted_by contact with urine or secretions from the mouth, eye, or nose of an infected animal or transmitted_by bite of an infected animal, especially rat. The infection has_symptom chills, has_symptom relapsing fever, has_symptom rash and has_symptom joint pain.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Rat_bite_fever
has db xref: url:http://protmed.uoradea.ro/facultate/anale/protectia_mediului/2009/miscellaneous/06.Indries%20Mirela%202.pdf

obsolete rat-bite fever
type: Class
has exact synonym: Rat bite fever (disorder)
has exact synonym: Rat-bite fever
has exact synonym: Rat-bite fever NOS (disorder)
has exact synonym: Rat-bite fever, unspecified (disorder)
has exact synonym: Unspecified rat-bite fever
has OBO namespace: disease_ontology
id: DOID:12097
in subset: zoonotic infectious disease
deprecated: true

obsolete Yersinia enterocolitica intestinal infectious disease
type: Class
IAO_0000115: A Yersinia infectious disease that involves infection of the intestine caused by Yersinia enterocolitica. The symptoms include fever, abdominal pain, and diarrhea (often bloody in children).
has exact synonym: Infection by Yersinia enterocolitica (disorder)
has exact synonym: Yersinia enterocolitis
has exact synonym: infectious disease by Yersinia enterocolitica
has exact synonym: intestinal infection due to yersinia enterocolitica
has OBO namespace: disease_ontology
id: DOID:12133
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Yersinia enterocolitica intestinal infectious disease
annotated property: IAO_0000115
annotated target: A Yersinia infectious disease that involves infection of the intestine caused by Yersinia enterocolitica. The symptoms include fever, abdominal pain, and diarrhea (often bloody in children).
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dbmd/diseaseinfo/yersinia_g.htm

Chagas disease
type: Class
IAO_0000115: A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
has alternative id: DOID:0050016
has alternative id: DOID:0050019
has alternative id: DOID:0050020
has db xref: GARD:6030
has db xref: ICD9CM:086.2
has db xref: KEGG:05142
has db xref: MESH:D014355
has db xref: ORDO:3386
has db xref: SNOMEDCT_US_2023_03_01:77506005
has db xref: UMLS_CUI:C0041234
has exact synonym: Chagas' disease
has exact synonym: chagas' disease with digestive system involvement
has exact synonym: chagas' disease with nervous system involvement
has exact synonym: chagas' disease with other organ involvement
has OBO namespace: disease_ontology
has related synonym: American trypanosomiasis
id: DOID:12140
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: Chagas disease
annotated property: IAO_0000115
annotated target: A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Chagas_disease

lymphocytic choriomeningitis
type: Class
IAO_0000115: A viral infectious disease that results in infection located in brain, or located in meninges, or located in brain and meninges, has_material_basis_in lymphocytic choriomeningitis virus (Mammarenavirus choriomeningitidis), which is transmitted by common house mouse, Mus musculus. The infection has symptom fever, has symptom lack of appetite, has symptom headache, has symptom muscle aches, has symptom malaise, has symptom nausea, and has symptom vomiting.
has alternative id: DOID:10662
has db xref: ICD10CM:A87.2
has db xref: MESH:D008216
has db xref: NCI:C174114
has db xref: SNOMEDCT_US_2023_03_01:192668002
has db xref: UMLS_CUI:C0024266
has exact synonym: LCM
has exact synonym: Lymphocytic choriomeningitis virus encephalomyelitis
has exact synonym: Lymphocytic meningitis
has exact synonym: Lymphocytic meningoencephalitis
has OBO namespace: disease_ontology
id: DOID:12155
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: lymphocytic choriomeningitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection located in brain, or located in meninges, or located in brain and meninges, has_material_basis_in lymphocytic choriomeningitis virus (Mammarenavirus choriomeningitidis), which is transmitted by common house mouse, Mus musculus. The infection has symptom fever, has symptom lack of appetite, has symptom headache, has symptom muscle aches, has symptom malaise, has symptom nausea, and has symptom vomiting.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis

Axiom
annotated source: lymphocytic choriomeningitis
annotated property: hasExactSynonym
annotated target: LCM
has synonym type: OMO_0003012

dengue disease
type: Class
IAO_0000115: A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.
has alternative id: DOID:0050142
has db xref: GARD:6254
has db xref: ICD10CM:A90
has db xref: ICD9CM:061
has db xref: MESH:D003715
has db xref: NCI:C34528
has db xref: SNOMEDCT_US_2023_03_01:38362002
has db xref: UMLS_CUI:C0011311
has exact synonym: Dengue Fever
has exact synonym: breakbone fever
has exact synonym: classic dengue
has OBO namespace: disease_ontology
has related synonym: classical dengue
id: DOID:12205
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: dengue disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.
type: ECO_0007637
type: ECO_0007643
has db xref: url:https://www.cdc.gov/dengue/about/index.html
has db xref: url:https://www.merriam-webster.com/dictionary/dengue#medicalDictionary
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK430732/

dengue hemorrhagic fever
type: Class
subclass of: dengue disease
IAO_0000115: A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus (Orthoflavivirus denguei) serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. Four distinct Dengue virus serotypes have been identified.
has db xref: ICD10CM:A91
has db xref: MESH:D019595
has db xref: NCI:C34683
has db xref: SNOMEDCT_US_2023_03_01:20927009
has db xref: UMLS_CUI:C0019100
has exact synonym: DHF
has OBO namespace: disease_ontology
has related synonym: Dengue haemorrhagic fever
id: DOID:12206
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: dengue hemorrhagic fever
annotated property: IAO_0000115
annotated target: A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus (Orthoflavivirus denguei) serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. Four distinct Dengue virus serotypes have been identified.
type: ECO_0007637
type: ECO_0007640
type: ECO_0007643
type: ECO_0007645
has db xref: url:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC88892/pdf/cm000480.pdf
has db xref: url:http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/001373.htm
has db xref: url:https://www.merriam-webster.com/medical/dengue%20hemorrhagic%20fever

Axiom
annotated source: dengue hemorrhagic fever
annotated property: hasExactSynonym
annotated target: DHF
has synonym type: OMO_0003012

Crimean-Congo hemorrhagic fever
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Crimean-Congo haemorrhagic fever virus (Orthonairovirus haemorrhagiae), which is transmitted_by Hyalomma ticks. The infection has_symptom headache, has_symptom high fever, has_symptom back pain, has_symptom joint pain, has_symptom stomach pain, has_symptom vomiting, has_symptom red eyes, has_symptom flushed face, has_symptom red throat, has_symptom petechiae (red spots) on the palate, has_symptom jaundice, has_symptom nosebleeds, and has_symptom blood in the feces and urine.
has db xref: ICD10CM:A98.0
has db xref: ICD9CM:065.0
has db xref: MESH:D006479
has db xref: NCI:C34682
has db xref: SNOMEDCT_US_2023_03_01:43489008
has db xref: UMLS_CUI:C0019099
has exact synonym: CHF Congo virus
has exact synonym: Congo-Crimean Hemorrhagic Fever
has exact synonym: Crimean hemorrhagic fever
has OBO namespace: disease_ontology
id: DOID:12287
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Crimean-Congo hemorrhagic fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Crimean-Congo haemorrhagic fever virus (Orthonairovirus haemorrhagiae), which is transmitted_by Hyalomma ticks. The infection has_symptom headache, has_symptom high fever, has_symptom back pain, has_symptom joint pain, has_symptom stomach pain, has_symptom vomiting, has_symptom red eyes, has_symptom flushed face, has_symptom red throat, has_symptom petechiae (red spots) on the palate, has_symptom jaundice, has_symptom nosebleeds, and has_symptom blood in the feces and urine.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/cchf.htm
has db xref: url:http://www.who.int/mediacentre/factsheets/fs208/en/

obsolete Chagas cardiomyopathy
type: Class
IAO_0000115: A Chagas disease that involves deterioration of the function of the myocardium caused due to Trypanosoma cruzi infection, which leads to heart rhythm abnormalities and may result in sudden death.
has alternative id: DOID:0050017
has alternative id: DOID:0050018
has exact synonym: Cardiovascular Trypanosomiasis
has exact synonym: Chagas' cardiomyopathy
has exact synonym: Chagas' disease cardiomyopathy
has exact synonym: Chagas' disease with heart involvement
has exact synonym: Chagas' disease with heart involvement (disorder)
has exact synonym: acute chagas' disease with heart involvement
has exact synonym: chronic chagas' disease with heart involvement
has OBO namespace: disease_ontology
id: DOID:12569
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Chagas cardiomyopathy
annotated property: IAO_0000115
annotated target: A Chagas disease that involves deterioration of the function of the myocardium caused due to Trypanosoma cruzi infection, which leads to heart rhythm abnormalities and may result in sudden death.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Chagas_disease

obsolete Chlamydophila psittaci pneumonia
type: Class
IAO_0000115: An ornithosis involving Chlamydophila psittaci infection, contracted by inhaling dust from the feathers or the waste of infected birds. The symptoms include fever, chills, fatigue, and loss of appetite. A cough develops, which is initially dry but later brings up greenish sputum.
has exact synonym: Ornithosis with pneumonia
has exact synonym: Ornithosis with pneumonia (disorder)
has exact synonym: louisiana pneumonia
has OBO namespace: disease_ontology
id: DOID:12888
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Chlamydophila psittaci pneumonia
annotated property: IAO_0000115
annotated target: An ornithosis involving Chlamydophila psittaci infection, contracted by inhaling dust from the feathers or the waste of infected birds. The symptoms include fever, chills, fatigue, and loss of appetite. A cough develops, which is initially dry but later brings up greenish sputum.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Ornithosis
has db xref: url:http://www.merck.com/mmhe/sec04/ch042/ch042b.html#SB_42_03

Plasmodium ovale malaria
type: Class
IAO_0000115: A malaria characterized as a relatively mild form caused by a parasite Plasmodium ovale, which is characterized by tertian chills and febrile paroxysms, and that ends spontaneously.
has db xref: ICD10CM:B53.0
has db xref: ICD9CM:084.3
has db xref: SNOMEDCT_US_2023_03_01:19341001
has db xref: UMLS_CUI:C0152072
has exact synonym: Malariaby Plasmodium ovale
has exact synonym: Ovale malaria
has OBO namespace: disease_ontology
id: DOID:12919
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: Plasmodium ovale malaria
annotated property: IAO_0000115
annotated target: A malaria characterized as a relatively mild form caused by a parasite Plasmodium ovale, which is characterized by tertian chills and febrile paroxysms, and that ends spontaneously.
type: ECO_0007643
has db xref: url:https://www.merriam-webster.com/medical/ovale%20malaria

tick-borne relapsing fever
type: Class
IAO_0000115: A relapsing fever that is characterized by relapsing or recurring episodes of fever, has_material_basis_in Borrelia hermsii, has_material_basis_in Borrelia parkeri or has_material_basis_in Borrelia duttoni, which are transmitted_by soft ticks (Ornithodoros parkeri and Ornithodoros hermsii). The infection has_symptom tachypnea, has_symptom tachycardia, has_symptom hepatosplenomegaly and has_symptom lymphadenopathy.
has db xref: ICD10CM:A68.1
has db xref: ICD9CM:087.1
has db xref: NCI:C34976
has db xref: SNOMEDCT_US_2023_03_01:10301003
has db xref: UMLS_CUI:C0035022
has exact synonym: Relapsing fever, tick-borne
has exact synonym: soft tick relapsing fever
has OBO namespace: disease_ontology
id: DOID:13036
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: tick-borne relapsing fever
annotated property: IAO_0000115
annotated target: A relapsing fever that is characterized by relapsing or recurring episodes of fever, has_material_basis_in Borrelia hermsii, has_material_basis_in Borrelia parkeri or has_material_basis_in Borrelia duttoni, which are transmitted_by soft ticks (Ornithodoros parkeri and Ornithodoros hermsii). The infection has_symptom tachypnea, has_symptom tachycardia, has_symptom hepatosplenomegaly and has_symptom lymphadenopathy.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Relapsing_fever

obsolete AIDS dementia complex
type: Class
IAO_0000115: A HIV encephalopathy that results_in infection in adults located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, has_symptom behavioral change, and has_symptom speech problems.
has exact synonym: AIDS Dementia
has exact synonym: HIV associated cognitive and motor complex
has exact synonym: HIV-associated dementia
has exact synonym: acquired immune deficiency syndrome dementia complex
has OBO namespace: disease_ontology
id: DOID:1305
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete AIDS dementia complex
annotated property: IAO_0000115
annotated target: A HIV encephalopathy that results_in infection in adults located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, has_symptom behavioral change, and has_symptom speech problems.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/AIDS_dementia_complex

obsolete HIV encephalopathy
type: Class
IAO_0000115: An acquired immunodeficiency syndrome that results_in infection located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, and has_symptom behavioral change.
has exact synonym: AIDS Encephalopathy
has exact synonym: Human immunodefiency virus encephalopathy
has OBO namespace: disease_ontology
id: DOID:1306
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV encephalopathy
annotated property: IAO_0000115
annotated target: An acquired immunodeficiency syndrome that results_in infection located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, and has_symptom behavioral change.
has db xref: url:http://emedicine.medscape.com/article/1166894-overview

obsolete AIDS related complex
type: Class
IAO_0000115: A Human immunodeficiency virus infectious disease that results_in infection with mild symptoms, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom swollen lymph glands, has_symptom fever, has_symptom diarrhea, and has_symptom weight loss.
has exact synonym: AIDS-like syndrome
has exact synonym: acquired immune deficiency syndrome (& [ARC])
has OBO namespace: disease_ontology
id: DOID:1308
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete AIDS related complex
annotated property: IAO_0000115
annotated target: A Human immunodeficiency virus infectious disease that results_in infection with mild symptoms, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom swollen lymph glands, has_symptom fever, has_symptom diarrhea, and has_symptom weight loss.
has db xref: url:http://chestofbooks.com/health/natural-cure/Ross-Horne/Health-and-Survival-in-the-21st-Century/AIDS-Related-Complex-ARC.html
has db xref: url:http://www.medterms.com/script/main/art.asp?articlekey=10924

obsolete HIV-associated nephropathy
type: Class
IAO_0000115: A renal infectious disease and is_a Human immunodeficiency virus infectious disease that results_in infection located_in kidney, has_material_basis_in has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom nephrotic-range proteinuria (greater than 3.5 g/d), has_symptom azotemia, has_symptom hypoalbuminemia, and has_symptom hyperlipidemia.
has exact synonym: AIDS nephropathy
has exact synonym: AIDS-Related nephropathy
has exact synonym: AIDS-associated nephropathy
has OBO namespace: disease_ontology
id: DOID:1311
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV-associated nephropathy
annotated property: IAO_0000115
annotated target: A renal infectious disease and is_a Human immunodeficiency virus infectious disease that results_in infection located_in kidney, has_material_basis_in has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom nephrotic-range proteinuria (greater than 3.5 g/d), has_symptom azotemia, has_symptom hypoalbuminemia, and has_symptom hyperlipidemia.
has db xref: url:http://emedicine.medscape.com/article/246031-overview

obsolete HIV wasting syndrome
type: Class
IAO_0000115: An acquired immunodeficiency syndrome that results_in involuntary loss of more than 10% of body weight, plus more than 30 days of either diarrhea, or weakness and fever, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2.
has exact synonym: Human immunodeficiency virus infection wasting syndrome
has OBO namespace: disease_ontology
has related synonym: AIDS wasting syndrome
id: DOID:1313
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV wasting syndrome
annotated property: IAO_0000115
annotated target: An acquired immunodeficiency syndrome that results_in involuntary loss of more than 10% of body weight, plus more than 30 days of either diarrhea, or weakness and fever, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/AIDS_wasting_syndrome
has db xref: url:http://www.aidsinfonet.org/fact_sheets/view/519

oculoglandular tularemia
type: Class
subclass of: tularemia
IAO_0000115: A tularemia that results_in inflammation of eye and swelling of lymph glands in front of the ear.
has db xref: ICD10CM:A21.1
has db xref: ICD9CM:021.3
has db xref: SNOMEDCT_US_2023_03_01:73363000
has db xref: UMLS_CUI:C0152944
has OBO namespace: disease_ontology
id: DOID:13226
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: oculoglandular tularemia
annotated property: IAO_0000115
annotated target: A tularemia that results_in inflammation of eye and swelling of lymph glands in front of the ear.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/tularemia/signssymptoms/

Haverhill fever
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Streptobacillus moniliformis, which is transmitted_by contact with urine or secretions from the mouth, eye, or nose of an infected animal or transmitted_by bite of an infected animal, especially rat. The infection has_symptom chills, has_symptom fever, has_symptom rash and has_symptom joint pain.
has db xref: ICD10CM:A25.1
has db xref: ICD9CM:026.1
has db xref: SNOMEDCT_US_2023_03_01:52138004
has db xref: UMLS_CUI:C0152063
has exact synonym: Streptobacillary fever
has OBO namespace: disease_ontology
has related synonym: Streptobacillary rat-bite fever
has related synonym: Streptobacillosis
id: DOID:13238
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Haverhill fever
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Streptobacillus moniliformis, which is transmitted_by contact with urine or secretions from the mouth, eye, or nose of an infected animal or transmitted_by bite of an infected animal, especially rat. The infection has_symptom chills, has_symptom fever, has_symptom rash and has_symptom joint pain.
has db xref: url:https://en.wikipedia.org/wiki/Haverhill_fever

obsolete HIV enteropathy
type: Class
IAO_0000115: A Human immunodeficiency virus infectious disease that results_in infection characterized by chronic diarrhea lasting longer than 1 month, without an identified infectious cause after thorough evaluation, in an HIV-positive individual, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. It is observed that HIV-infected individuals have histologic abnormalities of the gastrointestinal mucosa, malabsorption, and lymphocyte depletion causing diarrhea, increased gastrointestinal inflammation, increased intestinal permeability, and malabsorption of bile acid and vitamin B12.
has OBO namespace: disease_ontology
id: DOID:13251
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV enteropathy
annotated property: IAO_0000115
annotated target: A Human immunodeficiency virus infectious disease that results_in infection characterized by chronic diarrhea lasting longer than 1 month, without an identified infectious cause after thorough evaluation, in an HIV-positive individual, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. It is observed that HIV-infected individuals have histologic abnormalities of the gastrointestinal mucosa, malabsorption, and lymphocyte depletion causing diarrhea, increased gastrointestinal inflammation, increased intestinal permeability, and malabsorption of bile acid and vitamin B12.
type: ECO_0007645
has db xref: url:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777614/pdf/nihms-156875.pdf

obsolete Salmonella pneumonia
type: Class
IAO_0000115: A Salmonella infectious disease that is caused by Gram-negative bacteria of genus Salmonella which is rare in adults, although more common in children in the tropics. This infection is complicated by suppuration with lung abscess or empyema formation.
has exact synonym: Salmonella pneumonia (disorder)
has OBO namespace: disease_ontology
id: DOID:13278
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Salmonella pneumonia
annotated property: IAO_0000115
annotated target: A Salmonella infectious disease that is caused by Gram-negative bacteria of genus Salmonella which is rare in adults, although more common in children in the tropics. This infection is complicated by suppuration with lung abscess or empyema formation.
has db xref: url:http://books.google.com/books?id=fYgVmmMKS50C&pg=RA1-PA422&lpg#v=onepage&q=&f=false

Rift Valley fever
type: Class
IAO_0000115: A viral infectious disease that results_in infection, has_material_basis_in Rift Valley fever virus (Phlebovirus riftense), which is transmitted_by Aedes mosquitoes. The virus affects domestic animals (cattle, buffalo, sheep, goats, and camels) and humans. The infection has_symptom jaundice, has_symptom vomiting blood, has_symptom passing blood in the feces, has_symptom ecchymoses (caused by bleeding in the skin), has_symptom bleeding from the nose or gums, has_symptom menorrhagia and has_symptom bleeding from venepuncture sites.
has db xref: ICD10CM:A92.4
has db xref: MESH:D012295
has db xref: NCI:C128419
has db xref: ORDO:319251
has db xref: SNOMEDCT_US_2025_05_01:402917003
has db xref: UMLS_CUI:C0035613
has OBO namespace: disease_ontology
id: DOID:1328
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Rift Valley fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, has_material_basis_in Rift Valley fever virus (Phlebovirus riftense), which is transmitted_by Aedes mosquitoes. The virus affects domestic animals (cattle, buffalo, sheep, goats, and camels) and humans. The infection has_symptom jaundice, has_symptom vomiting blood, has_symptom passing blood in the feces, has_symptom ecchymoses (caused by bleeding in the skin), has_symptom bleeding from the nose or gums, has_symptom menorrhagia and has_symptom bleeding from venepuncture sites.
type: ECO_0007637
has db xref: url:http://www.who.int/mediacentre/factsheets/fs207/en/
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC8009587/
has db xref: url:https://www.who.int/news-room/fact-sheets/detail/rift-valley-fever

scrub typhus
type: Class
subclass of: typhus
IAO_0000115: A typhus that has_material_basis_in Orientia tsutsugamushi, which is transmitted by trombiculid mites (Leptotrombidium deliense). The infection has symptom fever, has symptom headache, has symptom muscle pain, has symptom cough, has symptom maculopapular rash, has symptom eschar, has symptom splenomegaly and has symptom lymphadenopathy.
has db xref: ICD10CM:A75.3
has db xref: ICD9CM:081.2
has db xref: MESH:D012612
has db xref: SNOMEDCT_US_2023_03_01:73911003
has db xref: UMLS_CUI:C0036472
has exact synonym: Japanese river fever
has exact synonym: Kedani fever
has exact synonym: Scrub mite-borne typhus
has exact synonym: Tsutsugamushi
has exact synonym: Tsutsugamushi disease
has OBO namespace: disease_ontology
has related synonym: Chigger-borne rickettsiosis
has related synonym: Chigger-borne typhus
has related synonym: Mite-borne rickettsiosis
has related synonym: Mite-borne typhus
has related synonym: Scrub (mite-borne) typhus
has related synonym: Tropical typhus
has related synonym: Tsutsugamushi fever
has related synonym: Typhus fever due to Rickettsia tsutsugamushi
id: DOID:13371
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: scrub typhus
annotated property: IAO_0000115
annotated target: A typhus that has_material_basis_in Orientia tsutsugamushi, which is transmitted by trombiculid mites (Leptotrombidium deliense). The infection has symptom fever, has symptom headache, has symptom muscle pain, has symptom cough, has symptom maculopapular rash, has symptom eschar, has symptom splenomegaly and has symptom lymphadenopathy.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Scrub_typhus

gastrointestinal anthrax
type: Class
subclass of: anthrax disease
IAO_0000115: An anthrax disease that results in infection located in mucosa of gastrointestinal tract, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.
has db xref: ICD10CM:A22.2
has db xref: ICD9CM:022.2
has db xref: MESH:C571911
has db xref: SNOMEDCT_US_2023_03_01:186302005
has db xref: UMLS_CUI:C0152945
has OBO namespace: disease_ontology
id: DOID:13386
in subset: DO infectious disease slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: gastrointestinal anthrax
annotated property: IAO_0000115
annotated target: An anthrax disease that results in infection located in mucosa of gastrointestinal tract, has_material_basis_in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.
type: ECO_0007638
type: ECO_0007645
has db xref: url:https://en.wikipedia.org/wiki/Anthrax#Gastrointestinal

glanders
type: Class
IAO_0000115: A primary bacterial infectious disease that results in septicemic infection, has_material_basis_in Burkholderia mallei, which is transmitted by contact with tissues or body fluids of infected animals, or through mucosal surfaces such as the eyes and nose. The infection has symptom fever, has symptom chills, has symptom sweating, has symptom muscle aches, has symptom chest pain, has symptom muscle tightness, has symptom headache, has symptom mucopurulent nasal discharge, and has symptom nodular lesions in the lungs.
has db xref: GARD:9536
has db xref: ICD10CM:A24.0
has db xref: ICD9CM:024
has db xref: MESH:D005896
has db xref: NCI:C34638
has db xref: SNOMEDCT_US_2023_03_01:4639008
has db xref: UMLS_CUI:C0017589
has exact synonym: Farcy pipes
has exact synonym: Infection due to Pseudomonas mallei
has OBO namespace: disease_ontology
id: DOID:13444
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: glanders
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results in septicemic infection, has_material_basis_in Burkholderia mallei, which is transmitted by contact with tissues or body fluids of infected animals, or through mucosal surfaces such as the eyes and nose. The infection has symptom fever, has symptom chills, has symptom sweating, has symptom muscle aches, has symptom chest pain, has symptom muscle tightness, has symptom headache, has symptom mucopurulent nasal discharge, and has symptom nodular lesions in the lungs.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/nczved/divisions/dfbmd/diseases/glanders/

urinary schistosomiasis
type: Class
IAO_0000115: A schistosomiasis that involves parasitic infection of the urinary tract caused by a digenetic trematode Schistosoma haematobium causing cystitis, ureteritis, fibrosis of the bladder and haematuria, which can progress to bladder cancer.
has db xref: ICD9CM:120.0
has db xref: MESH:D012553
has db xref: NCI:C39294
has db xref: SNOMEDCT_US_2023_03_01:60979006
has db xref: UMLS_CUI:C0276926
has exact synonym: Schistosoma Hematobium Infection
has exact synonym: Schistosoma haematobium
has exact synonym: Schistosoma hematobium infectious disease
has exact synonym: Schistosomiasis due to schistosoma haematobium
has exact synonym: Schistosomiasis of bladder
has exact synonym: Vesical schistosomiasis
has exact synonym: bladder Schistosomiasis
has exact synonym: cystitis with bilharziasis
has OBO namespace: disease_ontology
has related synonym: Schistosoma haematobium infection
id: DOID:1394
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: urinary schistosomiasis
annotated property: IAO_0000115
annotated target: A schistosomiasis that involves parasitic infection of the urinary tract caused by a digenetic trematode Schistosoma haematobium causing cystitis, ureteritis, fibrosis of the bladder and haematuria, which can progress to bladder cancer.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Schistosoma_haematobium
has db xref: url:http://www.dpd.cdc.gov/dpdx/HTML/Schistosomiasis.htm

Brucella canis brucellosis
type: Class
subclass of: brucellosis
IAO_0000115: A brucellosis involving an infection caused by Brucella canis in dogs and humans. The disease has_symptom fever, has_symptom sweats, has_symptom weakness, has_symptom weight loss, has_symptom headache, has_symptom lymphadenopathy and has_symptom splenomegaly.
has db xref: ICD10CM:A23.3
has db xref: ICD9CM:023.3
has db xref: SNOMEDCT_US_2023_03_01:428174001
has db xref: UMLS_CUI:C0494040
has OBO namespace: disease_ontology
id: DOID:14019
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Brucella canis brucellosis
annotated property: IAO_0000115
annotated target: A brucellosis involving an infection caused by Brucella canis in dogs and humans. The disease has_symptom fever, has_symptom sweats, has_symptom weakness, has_symptom weight loss, has_symptom headache, has_symptom lymphadenopathy and has_symptom splenomegaly.
type: ECO_0007637
type: ECO_0007645
has db xref: url:http://www.cdc.gov/ncidod/dbmd/diseaseinfo/Brucellosis_g.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/1172954

boutonneuse fever
type: Class
IAO_0000115: A spotted fever that has_material_basis_in Rickettsia conorii subsp conorii, which is transmitted_by dog tick (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities.
has alternative id: DOID:0050039
has alternative id: DOID:0050040
has alternative id: DOID:0050044
has alternative id: DOID:0050045
has db xref: ICD10CM:A77.1
has db xref: ICD9CM:082.1
has db xref: MESH:D001907
has db xref: SNOMEDCT_US_2023_03_01:186779000
has db xref: UMLS_CUI:C0006060
has exact synonym: African tick typhus
has exact synonym: Rickettsia conorii spotted fever
has exact synonym: South African tick-bite fever
has exact synonym: kenya tick typhus
has exact synonym: marseilles fever
has OBO namespace: disease_ontology
has related synonym: Boutonneuse disease
has related synonym: Conor and Bruch's disease
has related synonym: Kenya fever
has related synonym: Kenyan tick typhus
has related synonym: Mediterranean spotted fever
has related synonym: Mediterranean tick fever
id: DOID:14095
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: boutonneuse fever
annotated property: IAO_0000115
annotated target: A spotted fever that has_material_basis_in Rickettsia conorii subsp conorii, which is transmitted_by dog tick (Rhipicephalus sanguineus). The infection has_symptom fever, has_symptom eschar (usually single), has_symptom regional adenopathy, has_symptom maculopapular rash on extremities.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Boutonneuse_fever
has db xref: url:http://www.cdc.gov/otherspottedfever/index.html

gastrointestinal tularemia
type: Class
subclass of: tularemia
IAO_0000115: A tularemia that results in formation of ulcerative lesions located in gastrointestinal tract. The infection has symptom fever, has symptom chills, has symptom malaise, has symptom muscle aches, and has symptom vomiting.
has alternative id: DOID:0050071
has db xref: ICD9CM:021.1
has db xref: ICD9CM:021.8
has db xref: SNOMEDCT_US_2023_03_01:186292001
has db xref: SNOMEDCT_US_2023_03_01:186298002
has db xref: UMLS_CUI:C0029835
has db xref: UMLS_CUI:C0152942
has exact synonym: Enteric tularemia
has exact synonym: intestinal tularaemia
has OBO namespace: disease_ontology
id: DOID:14239
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: gastrointestinal tularemia
annotated property: IAO_0000115
annotated target: A tularemia that results in formation of ulcerative lesions located in gastrointestinal tract. The infection has symptom fever, has symptom chills, has symptom malaise, has symptom muscle aches, and has symptom vomiting.
type: ECO_0007637
has db xref: url:https://www.cdc.gov/tularemia/index.html

dipetalonemiasis
type: Class
IAO_0000115: A filariasis that is a zoonotic infection caused by the nematode of the genus Dipetalonema, which is transmitted accidentally to humans from porcupines, beavers and other mammals by mosquitoes. The adult worms live subcutaneously or in body cavities or in the eyes of humans. Dead worms cause hypersensitivity necrosis with eosinophils, followed by granulomatous reaction and fibrosis.
has db xref: ICD9CM:125.4
has db xref: MESH:D004154
has db xref: NCI:C34540
has db xref: SNOMEDCT_US_2023_03_01:15629006
has db xref: UMLS_CUI:C0012517
has exact synonym: Infection by Dipetalonema
has exact synonym: Infection by Dipetalonema perstans
has exact synonym: dipetalonema infectious disease
has OBO namespace: disease_ontology
id: DOID:14422
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: dipetalonemiasis
annotated property: IAO_0000115
annotated target: A filariasis that is a zoonotic infection caused by the nematode of the genus Dipetalonema, which is transmitted accidentally to humans from porcupines, beavers and other mammals by mosquitoes. The adult worms live subcutaneously or in body cavities or in the eyes of humans. Dead worms cause hypersensitivity necrosis with eosinophils, followed by granulomatous reaction and fibrosis.
type: ECO_0007646
has db xref: url:http://books.google.com/books?id=OBZbR4vpg0YC&pg=PA158&lpg#v=onepage&q&f=false

Brucella melitensis brucellosis
type: Class
subclass of: brucellosis
IAO_0000115: A brucellosis that involves an infection caused by Brucella melitensis in cattle, goats, sheep and humans. The disease has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom limb pain and has_symptom back pain.
has db xref: ICD10CM:A23.0
has db xref: ICD9CM:023.0
has db xref: SNOMEDCT_US_2023_03_01:186305007
has db xref: UMLS_CUI:C0302362
has OBO namespace: disease_ontology
id: DOID:14456
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Brucella melitensis brucellosis
annotated property: IAO_0000115
annotated target: A brucellosis that involves an infection caused by Brucella melitensis in cattle, goats, sheep and humans. The disease has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom limb pain and has_symptom back pain.
type: ECO_0007645
has db xref: url:http://www.bmj.com/cgi/reprint/1/5644/612.pdf

Brucella abortus brucellosis
type: Class
subclass of: brucellosis
IAO_0000115: A brucellosis that involves an infection caused by Brucella abortus in cattle and humans. The disease has_symptom fever, has_symptom chills, has_symptom sweats, has_symptom weight loss, has_symptom malaise, has_symptom headaches, has_symptom myalgia, and has_symptom arthralgia.
has db xref: ICD10CM:A23.1
has db xref: ICD9CM:023.1
has db xref: MESH:D002007
has db xref: SNOMEDCT_US_2023_03_01:427795000
has db xref: UMLS_CUI:C0302363
has OBO namespace: disease_ontology
id: DOID:14457
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: Brucella abortus brucellosis
annotated property: IAO_0000115
annotated target: A brucellosis that involves an infection caused by Brucella abortus in cattle and humans. The disease has_symptom fever, has_symptom chills, has_symptom sweats, has_symptom weight loss, has_symptom malaise, has_symptom headaches, has_symptom myalgia, and has_symptom arthralgia.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dbmd/diseaseinfo/Brucellosis_g.htm
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/10790142

hantavirus pulmonary syndrome
type: Class
IAO_0000115: A viral infectious disease that results in infection located in lung, has_material_basis_in Orthohantavirus sinnombreense, transmitted by deer mouse (Myodes glareolus), has_material_basis_in Orthohantavirus nigrorivense, transmitted by cotton rat (Sigmodon hispidus), has_material_basis_in Orthohantavirus bayoui, transmitted by marsh rice rat (Oryzomys palustris), has_material_basis_in Orthohantavirus negraense, transmitted by small vesper mouse (Calomys laucha), or has_material_basis_in Orthohantavirus andesense, transmitted by rice rat (Oligoryzomys longicaudatus). The infection has _symptom fever, muscle pain, headache, cough, vomiting, and chills which rapidly progress to bilateral interstitial pulmonary infiltrates occurrence, pulmonary edema and hypoxia often resulting in death from shock or cardiac complications.
has db xref: GARD:69
has db xref: ICD10CM:B33.4
has db xref: MESH:D018804
has db xref: NCI:C84747
has db xref: ORDO:319247
has db xref: SNOMEDCT_US_2023_03_01:120639003
has db xref: UMLS_CUI:C0243025
has exact synonym: HPS
has OBO namespace: disease_ontology
id: DOID:14472
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease
broad match: ICD9CM:079.81
broad match: ICD9CM:480.8

Axiom
annotated source: hantavirus pulmonary syndrome
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection located in lung, has_material_basis_in Orthohantavirus sinnombreense, transmitted by deer mouse (Myodes glareolus), has_material_basis_in Orthohantavirus nigrorivense, transmitted by cotton rat (Sigmodon hispidus), has_material_basis_in Orthohantavirus bayoui, transmitted by marsh rice rat (Oryzomys palustris), has_material_basis_in Orthohantavirus negraense, transmitted by small vesper mouse (Calomys laucha), or has_material_basis_in Orthohantavirus andesense, transmitted by rice rat (Oligoryzomys longicaudatus). The infection has _symptom fever, muscle pain, headache, cough, vomiting, and chills which rapidly progress to bilateral interstitial pulmonary infiltrates occurrence, pulmonary edema and hypoxia often resulting in death from shock or cardiac complications.
type: ECO_0007637
type: ECO_0007643
has db xref: url:http://www.cdc.gov/ncidod/diseases/hanta/hps/noframes/generalinfoindex.htm
has db xref: url:http://www.ncbi.nlm.nih.gov/sites/entrez/10742726
has db xref: url:https://www.merriam-webster.com/medical/hantavirus%20pulmonary%20syndrome

Axiom
annotated source: hantavirus pulmonary syndrome
annotated property: hasExactSynonym
annotated target: HPS
has synonym type: OMO_0003012

obsolete Salmonella septicemia
type: Class
has exact synonym: Salmonella septicemia (disorder)
has OBO namespace: disease_ontology
id: DOID:1465
in subset: GOLD
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

cryptosporidiosis
type: Class
IAO_0000115: A coccidiosis that involves a parasitic protozoan infection of the intestine of humans and a wide range of animals caused by Cryptosporidium species, through contaminated water and food, The symptoms include watery diarrhea, dehydration, weight loss, abdominal pain, fever, nausea and vomiting. Cryptosporidium infections have also been found in other digestive tract organs, the lungs, and conjunctiva. Immunocompromised persons are at greater risk of developing the infection.
has alternative id: DOID:1732
has db xref: GARD:6219
has db xref: ICD10CM:A07.2
has db xref: ICD9CM:007.4
has db xref: MESH:D003457
has db xref: NCI:C128408
has db xref: SNOMEDCT_US_2023_03_01:186126003
has db xref: UMLS_CUI:C0010418
has exact synonym: Cryptosporidial gastroenteritis
has exact synonym: Infection by Cryptosporidium
has exact synonym: intestinal cryptosporidiosis
has OBO namespace: disease_ontology
id: DOID:1733
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: cryptosporidiosis
annotated property: IAO_0000115
annotated target: A coccidiosis that involves a parasitic protozoan infection of the intestine of humans and a wide range of animals caused by Cryptosporidium species, through contaminated water and food, The symptoms include watery diarrhea, dehydration, weight loss, abdominal pain, fever, nausea and vomiting. Cryptosporidium infections have also been found in other digestive tract organs, the lungs, and conjunctiva. Immunocompromised persons are at greater risk of developing the infection.
type: ECO_0007637
has db xref: url:http://www.dpd.cdc.gov/DPDx/HTML/Cryptosporidiosis.htm

pneumonic tularemia
type: Class
subclass of: tularemia
IAO_0000115: A tularemia that is located_in lungs. The bacteria are transmitted_by breathing dusts or aerosols containing the organisms. The infection has_symptom cough, has_symptom chest has_symptom pain, and has_symptom difficulty breathing.
has db xref: ICD10CM:A21.2
has db xref: ICD9CM:021.2
has db xref: SNOMEDCT_US_2023_03_01:186297007
has db xref: UMLS_CUI:C0339946
has exact synonym: Pneumonic tularaemia
has exact synonym: bronchopneumonic tularemia
has exact synonym: pulmonary tularemia
has OBO namespace: disease_ontology
id: DOID:2122
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: pneumonic tularemia
annotated property: IAO_0000115
annotated target: A tularemia that is located_in lungs. The bacteria are transmitted_by breathing dusts or aerosols containing the organisms. The infection has_symptom cough, has_symptom chest has_symptom pain, and has_symptom difficulty breathing.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/tularemia/signssymptoms/

tularemia
type: Class
IAO_0000115: A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues.
has db xref: GARD:396
has db xref: ICD9CM:021.8
has db xref: SNOMEDCT_US_2023_03_01:186298002
has db xref: UMLS_CUI:C0029835
has OBO namespace: disease_ontology
id: DOID:2123
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: gram-negative bacterial infectious disease
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: tularemia
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/tularemia/index.html

obsolete Treponema infectious disease
type: Class
has exact synonym: Treponema infection
has exact synonym: Treponemal disease
has exact synonym: Treponemal infection
has exact synonym: Treponemal infectious disease
has OBO namespace: disease_ontology
id: DOID:2265
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

leptospirosis
type: Class
IAO_0000115: A primary bacterial infectious disease that involves systemic infection, has_material_basis_in Leptospira, which is transmitted by contact with water, food, or soil containing urine from the infected animals. The infection has symptom jaundice, has symptom chills, has symptom fever, has symptom muscle pain, and has symptom hepatomegaly.
has alternative id: DOID:11348
has db xref: GARD:7881
has db xref: ICD10CM:A27
has db xref: ICD10CM:A27.0
has db xref: ICD9CM:100
has db xref: ICD9CM:100.0
has db xref: MESH:D007922
has db xref: MESH:D014895
has db xref: NCI:C84825
has db xref: SNOMEDCT_US_2023_03_01:154391003
has db xref: SNOMEDCT_US_2023_03_01:398067003
has db xref: UMLS_CUI:C0023364
has db xref: UMLS_CUI:C0043102
has exact synonym: Fort Bragg fever
has exact synonym: Leptospirosis icterohaemorrhagica
has exact synonym: Rat Catcher's Yellows
has exact synonym: Weil's disease
has exact synonym: nanukayami fever
has exact synonym: spirochetal jaundice
has OBO namespace: disease_ontology
id: DOID:2297
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: leptospirosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that involves systemic infection, has_material_basis_in Leptospira, which is transmitted by contact with water, food, or soil containing urine from the infected animals. The infection has symptom jaundice, has symptom chills, has symptom fever, has symptom muscle pain, and has symptom hepatomegaly.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Leptospirosis

West Nile encephalitis
type: Class
IAO_0000115: A viral infectious disease that results in inflammation located in brain, has_material_basis_in West Nile virus (Orthoflavivirus nilense), which is transmitted_by Culex, Aedes, or Anopheles species of mosquitoes. The infection has_symptom high fever, has_symptom headache, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, has_symptom muscle weakness, has_symptom vision loss, has_symptom numbness, and has_symptom paralysis.
has db xref: GARD:9959
has db xref: ICD10CM:A92.31
has db xref: ICD9CM:066.41
has db xref: MESH:D014901
has db xref: SNOMEDCT_US_2023_03_01:392662004
has db xref: UMLS_CUI:C0751583
has exact synonym: West Nile Fever with encephalitis
has exact synonym: West Nile fever encephalitis
has OBO namespace: disease_ontology
id: DOID:2365
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: West Nile encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in inflammation located in brain, has_material_basis_in West Nile virus (Orthoflavivirus nilense), which is transmitted_by Culex, Aedes, or Anopheles species of mosquitoes. The infection has_symptom high fever, has_symptom headache, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, has_symptom muscle weakness, has_symptom vision loss, has_symptom numbness, and has_symptom paralysis.
type: ECO_0007637
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC1125772/
has db xref: url:https://www.cdc.gov/west-nile-virus/hcp/clinical-signs/

West Nile fever
type: Class
IAO_0000115: A viral infectious disease that results_in infection, has_material_basis_in West Nile virus (Orthoflavivirus nilense), which is transmitted_by Culex and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom body ache, has_symptom nausea, has_symptom maculopapular rash and has_symptom vomiting.
has db xref: ICD10CM:A92.3
has db xref: ICD9CM:066.4
has db xref: MESH:D014901
has db xref: SNOMEDCT_US_2023_03_01:12381007
has db xref: UMLS_CUI:C0043124
has OBO namespace: disease_ontology
id: DOID:2366
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: West Nile fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, has_material_basis_in West Nile virus (Orthoflavivirus nilense), which is transmitted_by Culex and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom body ache, has_symptom nausea, has_symptom maculopapular rash and has_symptom vomiting.
type: ECO_0007637
has db xref: url:http://www.cfsph.iastate.edu/FastFacts/pdfs/west_nile_fever_F.pdf
has db xref: url:https://en.wikipedia.org/wiki/West_Nile_fever
has db xref: url:https://www.cdc.gov/west-nile-virus/about/

obsolete Erysipelothrix rhusiopathiae infectious disease
type: Class
has exact synonym: Infection due to E. rhusiopathiae
has exact synonym: Infection due to Erysipelothrix rhusiopathiae
has OBO namespace: disease_ontology
id: DOID:2471
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete Hantavirus infectious disease
type: Class
IAO_0000115: A viral infectious disease that results_in infection, located_in lungs or located_in kidney, has_material_basis_in Hantavirus, which is transmitted_by rodents. The infection has_symptom renal failure, has_symptom hemorrhagic manifestations, and has_symptom pulmonary edema.
has OBO namespace: disease_ontology
id: DOID:2880
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Hantavirus infectious disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, located_in lungs or located_in kidney, has_material_basis_in Hantavirus, which is transmitted_by rodents. The infection has_symptom renal failure, has_symptom hemorrhagic manifestations, and has_symptom pulmonary edema.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Hantavirus_pulmonary_syndrome#Hantavirus_.28cardio-.29pulmonary_syndrome

Newcastle disease
type: Class
IAO_0000115: A viral infectious disease that results_in infection in birds and humans, has_material_basis_in Newcastle disease virus (Orthoavulavirus javaense), which is transmitted_by contact with feces and urine of an infected bird, or transmitted_by fomites. The infection has_symptom conjunctivitis, has_symptom headache, and has_symptom lacrimation in humans, and has_symptom gasping, has_symptom coughing, has_symptom twisting of head and neck, has_symptom circling, has_symptom complete paralysis, has_symptom watery diarrhea, and has_symptom reduced egg production in birds.
has db xref: MESH:D009521
has db xref: NCI:C34849
has db xref: SNOMEDCT_US_2023_03_01:258300000
has db xref: UMLS_CUI:C0027983
has exact synonym: Newcastle's disease
has exact synonym: Pseudo-fowlpest
has OBO namespace: disease_ontology
id: DOID:2929
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Newcastle disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection in birds and humans, has_material_basis_in Newcastle disease virus (Orthoavulavirus javaense), which is transmitted_by contact with feces and urine of an infected bird, or transmitted_by fomites. The infection has_symptom conjunctivitis, has_symptom headache, and has_symptom lacrimation in humans, and has_symptom gasping, has_symptom coughing, has_symptom twisting of head and neck, has_symptom circling, has_symptom complete paralysis, has_symptom watery diarrhea, and has_symptom reduced egg production in birds.
type: ECO_0007638
type: ECO_0007645
has db xref: url:https://en.wikipedia.org/wiki/Virulent_Newcastle_disease
has db xref: url:https://www.agric.wa.gov.au/livestock-biosecurity/newcastle-disease
has db xref: url:https://www.ncbi.nlm.nih.gov/articles/PMC1526237/
has db xref: url:https://www.ncbi.nlm.nih.gov/articles/PMC1822603/

aleutian mink disease
type: Class
IAO_0000115: A viral infectious disease that results_in inflammatory destruction located_in blood vessels of minks and rarely in humans, which has_material_basis_in Aleutian mink disease parvovirus (Amdoparvovirus carnivoran1, Amdoparvovirus carnivoran9, or Amdoparvovirus carnivoran10). The infection has_symptom weight loss, has_symptom hepatomegaly, has_symptom enlarged spleen, and has_symptom anemia.
has db xref: MESH:D000453
has db xref: SNOMEDCT_US_2023_03_01:62251004
has db xref: UMLS_CUI:C0002016
has exact synonym: Aleutian disease
has OBO namespace: disease_ontology
id: DOID:2934
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: aleutian mink disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in inflammatory destruction located_in blood vessels of minks and rarely in humans, which has_material_basis_in Aleutian mink disease parvovirus (Amdoparvovirus carnivoran1, Amdoparvovirus carnivoran9, or Amdoparvovirus carnivoran10). The infection has_symptom weight loss, has_symptom hepatomegaly, has_symptom enlarged spleen, and has_symptom anemia.
type: ECO_0007637
type: ECO_0007638
type: ECO_0007645
has db xref: url:http://en.wikipedia.org/wiki/Aleutian_Disease
has db xref: url:http://www.cdc.gov/eid/content/15/12/2040.htm
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC3044528/

severe acute respiratory syndrome
type: Class
IAO_0000115: A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.
has db xref: GARD:9237
has db xref: ICD10CM:J12.81
has db xref: ICD9CM:079.82
has db xref: MESH:D045169
has db xref: NCI:C85064
has db xref: SNOMEDCT_US_2023_03_01:398447004
has db xref: UMLS_CUI:C1175175
has exact synonym: SARS
has exact synonym: SARS-CoV infection
has OBO namespace: disease_ontology
id: DOID:2945
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: severe acute respiratory syndrome
annotated property: IAO_0000115
annotated target: A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.
type: ECO_0007638
type: ECO_0007643
has db xref: url:http://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome
has db xref: url:https://www.merriam-webster.com/dictionary/SARS#medicalDictionary
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK558977/

Axiom
annotated source: severe acute respiratory syndrome
annotated property: hasExactSynonym
annotated target: SARS
has synonym type: OMO_0003012

obsolete Yellow fever virus infectious disease
type: Class
IAO_0000115: A Flavivirus infectious disease that results_in infection, has_material_basis_in Yellow fever virus, which is transmitted_by mosquito bites. The infection has_symptom fever, has_symptom severe headache, has_symptom back pain, has_symptom muscle ache, has_symptom nausea, and has_symptom weakness.
has OBO namespace: disease_ontology
id: DOID:2947
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Yellow fever virus infectious disease
annotated property: IAO_0000115
annotated target: A Flavivirus infectious disease that results_in infection, has_material_basis_in Yellow fever virus, which is transmitted_by mosquito bites. The infection has_symptom fever, has_symptom severe headache, has_symptom back pain, has_symptom muscle ache, has_symptom nausea, and has_symptom weakness.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dvbid/yellowfever/YF_Symptoms.html

mpox
type: Class
IAO_0000115: A viral infectious disease that results in infection of primates, rodents and humans, located in skin, has_material_basis_in Monkeypox virus (Orthopoxvirus monkeypox), which is transmitted by contact with the animal's blood, body fluids, rash, or with the body fluids of a sick person, transmitted by fomites, and transmitted by respiratory droplets. The infection has symptom fever, has symptom muscle ache, has symptom headache, and has symptom lymphadenopathy.
has db xref: GARD:10722
has db xref: ICD10CM:B04
has db xref: ICD9CM:059.01
has db xref: MESH:D045908
has db xref: NCI:C128421
has db xref: SNOMEDCT_US_2023_03_01:240466002
has db xref: UMLS_CUI:C0276180
has exact synonym: monkeypox
has OBO namespace: disease_ontology
id: DOID:3292
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease
comment: November 2022 WHO name update.
broad match: ORDO:438279

Axiom
annotated source: mpox
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection of primates, rodents and humans, located in skin, has_material_basis_in Monkeypox virus (Orthopoxvirus monkeypox), which is transmitted by contact with the animal's blood, body fluids, rash, or with the body fluids of a sick person, transmitted by fomites, and transmitted by respiratory droplets. The infection has symptom fever, has symptom muscle ache, has symptom headache, and has symptom lymphadenopathy.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/monkeypox/factsheet2.htm
has db xref: url:https://www.who.int/news/item/28-11-2022-who-recommends-new-name-for-monkeypox-disease

obsolete Yersinia pseudotuberculosis infectious disease
type: Class
has exact synonym: Pasteurella pseudotuberculosis infection
has exact synonym: Pseudotuberculosis
has exact synonym: Pseudotuberculosis (disorder)
has OBO namespace: disease_ontology
id: DOID:3299
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

septicemic plague
type: Class
subclass of: plague
IAO_0000115: A plague that results_in infection located_in vasculature where bacterial endotoxins cause coagulation, which leads to formation of tiny clots throughout the body. The infection has_symptom fever, has_symptom chills, has_symptom prostration, has_symptom abdominal pain, has_symptom shock and has_symptom bleeding into skin and other organs.
has db xref: ICD10CM:A20.7
has db xref: ICD9CM:020.2
has db xref: MESH:D010930
has db xref: SNOMEDCT_US_2023_03_01:9012003
has db xref: UMLS_CUI:C0152936
has OBO namespace: disease_ontology
id: DOID:3481
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: septicemic plague
annotated property: IAO_0000115
annotated target: A plague that results_in infection located_in vasculature where bacterial endotoxins cause coagulation, which leads to formation of tiny clots throughout the body. The infection has_symptom fever, has_symptom chills, has_symptom prostration, has_symptom abdominal pain, has_symptom shock and has_symptom bleeding into skin and other organs.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Plague_%28disease%29#Septicemic_plague
has db xref: url:http://www.cdc.gov/ncidod/dvbid/plague/facts.htm

plague
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food.
has db xref: ICD10CM:A20
has db xref: ICD9CM:020
has db xref: MESH:D010930
has db xref: NCI:C85015
has db xref: SNOMEDCT_US_2023_03_01:58750007
has db xref: UMLS_CUI:C0032064
has OBO namespace: disease_ontology
id: DOID:3482
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: plague
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/29628173

obsolete pneumonic pasteurellosis
type: Class
IAO_0000115: A Pasteurella infectious disease that involves infection by the bacterium Mannheimia haemolytica and less frequently by Pasteurella multocida and Histophilus somni. After stress or viral infection, the replication rate of M. haemolytica in the upper respiratory tract increases rapidly, followed by inhalation and colonization of the lungs due to suppression of the host's defense mechanism. The bacterium produces exotoxin called leukotxin which interacts with the host's defense mechanism resulting in tissue damage with charactersistic necrosis, thrombosis, and exudation and the development of pneumonia.
has exact synonym: Pneumonic pasteurellosis
has OBO namespace: disease_ontology
id: DOID:3730
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete pneumonic pasteurellosis
annotated property: IAO_0000115
annotated target: A Pasteurella infectious disease that involves infection by the bacterium Mannheimia haemolytica and less frequently by Pasteurella multocida and Histophilus somni. After stress or viral infection, the replication rate of M. haemolytica in the upper respiratory tract increases rapidly, followed by inhalation and colonization of the lungs due to suppression of the host's defense mechanism. The bacterium produces exotoxin called leukotxin which interacts with the host's defense mechanism resulting in tissue damage with charactersistic necrosis, thrombosis, and exudation and the development of pneumonia.
has db xref: url:http://merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/121216.htm

obsolete bovine tuberculosis
type: Class
has exact synonym: Bovine tuberculosis (disorder)
has exact synonym: Infection due to Mycobacterium bovis (disorder)
has OBO namespace: disease_ontology
id: DOID:411
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

obsolete West Nile virus infectious disease
type: Class
IAO_0000115: A Flavivirus infectious disease that results_in infection in animals and humans, has_material_basis_in West Nile virus, which is transmitted_by Culex mosquitoes. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom nausea, has_symptom vomiting, has_symptom swollen lymph glands, or has_symptom skin rash on the chest, stomach and back.
has OBO namespace: disease_ontology
id: DOID:4121
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete West Nile virus infectious disease
annotated property: IAO_0000115
annotated target: A Flavivirus infectious disease that results_in infection in animals and humans, has_material_basis_in West Nile virus, which is transmitted_by Culex mosquitoes. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom nausea, has_symptom vomiting, has_symptom swollen lymph glands, or has_symptom skin rash on the chest, stomach and back.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/West_Nile_virus
has db xref: url:http://www.cdc.gov/ncidod/dvbid/westnile/wnv_factsheet.htm

encephalitozoonosis
type: Class
IAO_0000115: A microsporidiosis that is a zoonotic infectious disease results_in disseminated fungal infection in dogs, cats, hamsters, guinea pigs, rats, mice and humans, has_material_basis_in Encephalitozoon cuniculi, has_material_basis_in Encephalitozoon intestinalis or has_material_basis_in Encephalitozoon hellem.
has db xref: MESH:D016890
has db xref: SNOMEDCT_US_2023_03_01:12825006
has db xref: UMLS_CUI:C0085412
has exact synonym: Infection by Encephalitozoon
has OBO namespace: disease_ontology
id: DOID:4270
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: encephalitozoonosis
annotated property: IAO_0000115
annotated target: A microsporidiosis that is a zoonotic infectious disease results_in disseminated fungal infection in dogs, cats, hamsters, guinea pigs, rats, mice and humans, has_material_basis_in Encephalitozoon cuniculi, has_material_basis_in Encephalitozoon intestinalis or has_material_basis_in Encephalitozoon hellem.
type: ECO_0007645
has db xref: url:https://pubmed.ncbi.nlm.nih.gov/35202528/

Ebola virus disease
type: Class
IAO_0000115: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Bundibugyo virus (Orthoebolavirus bundibugyoense), Sudan ebolavirus (Orthoebolavirus sudanense), Tai Forest ebolavirus (Orthoebolavirus taiense), or Zaire ebolavirus (Orthoebolavirus zairense), which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding.
has db xref: GARD:2035
has db xref: ICD10CM:A98.4
has db xref: MESH:D019142
has db xref: NCI:C36171
has db xref: SNOMEDCT_US_2023_03_01:123323003
has db xref: UMLS_CUI:C0282687
has exact synonym: Ebola
has exact synonym: Ebola disease
has exact synonym: Ebola hemorrhagic fever
has OBO namespace: disease_ontology
id: DOID:4325
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Ebola virus disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Bundibugyo virus (Orthoebolavirus bundibugyoense), Sudan ebolavirus (Orthoebolavirus sudanense), Tai Forest ebolavirus (Orthoebolavirus taiense), or Zaire ebolavirus (Orthoebolavirus zairense), which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding.
type: ECO_0007637
has db xref: url:https://en.wikipedia.org/wiki/Ebola
has db xref: url:https://www.cdc.gov/ebola/about/
has db xref: url:https://www.nhs.uk/conditions/ebola/
has db xref: url:https://www.who.int/health-topics/ebola
has db xref: url:https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease

obsolete Henipavirus infectious disease
type: Class
IAO_0000115: A Paramyxoviridae infectious disease that results_in infection in domestic animals and humans, has_material_basis_in Henipavirus, which is transmitted_by direct contact with the urine, feces, and nasal secretions of an infected animal.
has OBO namespace: disease_ontology
id: DOID:4393
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete Henipavirus infectious disease
annotated property: IAO_0000115
annotated target: A Paramyxoviridae infectious disease that results_in infection in domestic animals and humans, has_material_basis_in Henipavirus, which is transmitted_by direct contact with the urine, feces, and nasal secretions of an infected animal.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Henipavirus
has db xref: url:http://www.expasy.org/viralzone/all_by_species/85.html

hepatitis E
type: Class
IAO_0000115: A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis E virus (Paslahepevirus balayani), which is transmitted_by ingestion of contaminated food. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom dark urine, has_symptom joint pain, and has_symptom jaundice.
has alternative id: DOID:12431
has db xref: GARD:9541
has db xref: MESH:D016751
has db xref: SNOMEDCT_US_2023_03_01:7111000119109
has db xref: UMLS_CUI:C0085293
has OBO namespace: disease_ontology
id: DOID:4411
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: zoonotic infectious disease

Axiom
annotated source: hepatitis E
annotated property: IAO_0000115
annotated target: A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis E virus (Paslahepevirus balayani), which is transmitted_by ingestion of contaminated food. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom dark urine, has_symptom joint pain, and has_symptom jaundice.
type: ECO_0007637
has db xref: url:https://www.cdc.gov/hepatitis-e/about/index.html
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK532278/
has db xref: url:https://www.who.int/news-room/fact-sheets/detail/hepatitis-e

avian influenza
type: Class
IAO_0000115: An influenza that results in infection located in respiratory tract of humans, domestic and wild birds, has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae), which is transmitted by contact with infected poultry. At least five strains of avian influenza A viruses (H5N1, H7N3, H7N2, H7N7 and H9N2) are known to cause human infections. The infection has_symptom fever, has_symptom cough, has_symptom sore throat, has_symptom muscle aches, has_symptom nausea, has_symptom diarrhea, has_symptom vomiting, has_symptom neurologic changes, has_symptom pneumonia, and has_symptom acute respiratory distress.
has db xref: ICD10CM:J09.X
has db xref: MESH:D005585
has db xref: SNOMEDCT_US_2023_03_01:55604004
has db xref: UMLS_CUI:C0016627
has exact synonym: avian flu
has exact synonym: bird flu
has OBO namespace: disease_ontology
id: DOID:4492
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: avian influenza
annotated property: IAO_0000115
annotated target: An influenza that results in infection located in respiratory tract of humans, domestic and wild birds, has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae), which is transmitted by contact with infected poultry. At least five strains of avian influenza A viruses (H5N1, H7N3, H7N2, H7N7 and H9N2) are known to cause human infections. The infection has_symptom fever, has_symptom cough, has_symptom sore throat, has_symptom muscle aches, has_symptom nausea, has_symptom diarrhea, has_symptom vomiting, has_symptom neurologic changes, has_symptom pneumonia, and has_symptom acute respiratory distress.
type: ECO_0007637
type: ECO_0007643
has db xref: url:http://www.cdc.gov/flu/avian/gen-info/avian-flu-humans.htm
has db xref: url:https://www.merriam-webster.com/dictionary/avian%20influenza#medicalDictionary
has db xref: url:https://www.who.int/news-room/fact-sheets/detail/influenza-(avian-and-other-zoonotic)

actinobacillosis
type: Class
IAO_0000115: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Actinobacillus ureae, which is a commensal of the human respiratory tract. The pathogen causes meningitis, endocarditis, bacteremia, atrophic rhinitis, bronchitis, pneumonia, conjunctivitis, peritonitis, and otitis media.
has db xref: MESH:D000187
has db xref: SNOMEDCT_US_2023_03_01:16140007
has db xref: UMLS_CUI:C0001247
has OBO namespace: disease_ontology
id: DOID:4974
in subset: DO infectious disease slim
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: actinobacillosis
annotated property: IAO_0000115
annotated target: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Actinobacillus ureae, which is a commensal of the human respiratory tract. The pathogen causes meningitis, endocarditis, bacteremia, atrophic rhinitis, bronchitis, pneumonia, conjunctivitis, peritonitis, and otitis media.
type: ECO_0007645
has db xref: url:https://www.merckvetmanual.com/generalized-conditions/actinobacillosis/actinobacillosis

melioidosis
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain.
has alternative id: DOID:0050062
has alternative id: DOID:0050064
has db xref: GARD:9546
has db xref: ICD10CM:A24.9
has db xref: ICD9CM:025
has db xref: MESH:D008554
has db xref: NCI:C128336
has db xref: SNOMEDCT_US_2023_03_01:428111003
has db xref: UMLS_CUI:C0025229
has exact synonym: Nightcliff gardener's disease
has exact synonym: Pseudoglanders
has exact synonym: Whitmore's disease
has exact synonym: acute and fulminating melioidosis
has exact synonym: subacute and chronic melioidosis
has OBO namespace: disease_ontology
id: DOID:5052
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: melioidosis
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/melioidosis/symptoms/index.html

borna disease
type: Class
IAO_0000115: A viral infectious disease that results_in infection, which affects dopaminergic neurotransmission located_in central nervous system, has_material_basis_in Borna disease virus (Orthobornavirus bornaense), which is transmitted_by contact with infected oronasal secretions. The infection has_symptom mood disturbances, has_symptom behaviour disturbances, has_symptom cognitive disturbances, has_symptom neurologic disturbances, and has_symptom movement impairment.
has db xref: MESH:D001890
has db xref: SNOMEDCT_US_2023_03_01:76851008
has db xref: UMLS_CUI:C0006023
has exact synonym: Enzootic encephalomyelitis
has OBO namespace: disease_ontology
id: DOID:5154
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: borna disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, which affects dopaminergic neurotransmission located_in central nervous system, has_material_basis_in Borna disease virus (Orthobornavirus bornaense), which is transmitted_by contact with infected oronasal secretions. The infection has_symptom mood disturbances, has_symptom behaviour disturbances, has_symptom cognitive disturbances, has_symptom neurologic disturbances, and has_symptom movement impairment.
type: ECO_0007645
has db xref: url:http://www.biomedcentral.com/1471-244X/10/70
has db xref: url:https://en.wikipedia.org/wiki/Borna_disease
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC6675037/

obsolete central nervous system AIDS arteritis
type: Class
IAO_0000115: A Human immunodeficiency virus infectious disease that results_in inflammation located_in wall of artery of the central nervous system, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2.
has OBO namespace: disease_ontology
id: DOID:524
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete central nervous system AIDS arteritis
annotated property: IAO_0000115
annotated target: A Human immunodeficiency virus infectious disease that results_in inflammation located_in wall of artery of the central nervous system, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2.
type: ECO_0007645
has db xref: url:http://jnnp.bmj.com/content/80/8/831.long

human immunodeficiency virus infectious disease
type: Class
IAO_0000115: A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
has db xref: ICD10CM:B20
has db xref: ICD9CM:042
has db xref: ICD9CM:042-042.99
has db xref: MESH:D015658
has db xref: NCI:C3108
has db xref: SNOMEDCT_US_2023_03_01:86406008
has db xref: UMLS_CUI:C0019693
has exact synonym: HIV infection
has OBO namespace: disease_ontology
id: DOID:526
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: human immunodeficiency virus infectious disease
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/HIV
has db xref: url:https://medlineplus.gov/hiv.html
has db xref: url:https://www.cdc.gov/hiv/about/index.html

obsolete AIDS retinopathy
type: Class
IAO_0000115: A Human immunodeficiency virus infectious disease that results_in microvascular changes located_in retina, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cotton-wool spots, has_symptom retinal hemorrhages, and has_symptom microaneurysms.
has OBO namespace: disease_ontology
id: DOID:6045
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete AIDS retinopathy
annotated property: IAO_0000115
annotated target: A Human immunodeficiency virus infectious disease that results_in microvascular changes located_in retina, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cotton-wool spots, has_symptom retinal hemorrhages, and has_symptom microaneurysms.
type: ECO_0007646
has db xref: url:http://www.ophthobook.com/chapters/infections

acquired immunodeficiency syndrome
type: Class
subclass of: human immunodeficiency virus infectious disease
IAO_0000115: A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
has db xref: EFO:0000765
has db xref: ICD10CM:B20
has db xref: MESH:D000163
has db xref: NCI:C2851
has db xref: SNOMEDCT_US_2023_03_01:62479008
has db xref: UMLS_CUI:C0001175
has exact synonym: AIDS
has exact synonym: acquired Immune deficiency
has OBO namespace: disease_ontology
has related synonym: acquired immune deficiency syndrome
id: DOID:635
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: acquired immunodeficiency syndrome
annotated property: IAO_0000115
annotated target: A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
type: ECO_0007638
type: ECO_0007643
has db xref: url:http://en.wikipedia.org/wiki/AIDS
has db xref: url:https://www.merriam-webster.com/dictionary/AIDS

Axiom
annotated source: acquired immunodeficiency syndrome
annotated property: hasExactSynonym
annotated target: AIDS
has synonym type: OMO_0003012

cutaneous anthrax
type: Class
subclass of: anthrax disease
IAO_0000115: An anthrax disease that results_in infection located_in skin, has_material_basis_in Bacillus anthracis, which is transmitted_by contact with infected animals or animal products. The infection has_symptom skin lesion that eventually forms an ulcer with a black center.
has db xref: GARD:8158
has db xref: ICD10CM:A22.0
has db xref: ICD9CM:022.0
has db xref: MESH:C531621
has db xref: SNOMEDCT_US_2023_03_01:84980006
has db xref: UMLS_CUI:C0003177
has OBO namespace: disease_ontology
id: DOID:7426
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: cutaneous anthrax
annotated property: IAO_0000115
annotated target: An anthrax disease that results_in infection located_in skin, has_material_basis_in Bacillus anthracis, which is transmitted_by contact with infected animals or animal products. The infection has_symptom skin lesion that eventually forms an ulcer with a black center.
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Anthrax#Skin

anthrax disease
type: Class
IAO_0000115: A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath.
has db xref: GARD:8157
has db xref: ICD10CM:A22
has db xref: ICD9CM:022
has db xref: MESH:D000881
has db xref: NCI:C84565
has db xref: SNOMEDCT_US_2023_03_01:154295005
has db xref: UMLS_CUI:C0003175
has OBO namespace: disease_ontology
id: DOID:7427
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: gram-positive bacterial infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: anthrax disease
annotated property: IAO_0000115
annotated target: A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath.
type: ECO_0007637
type: ECO_0007638
has db xref: url:https://en.wikipedia.org/wiki/Anthrax
has db xref: url:https://medlineplus.gov/ency/article/001325.htm
has db xref: url:https://www.cdc.gov/anthrax/basics/index.html
has db xref: url:https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectious-diseases/anthrax

obsolete HIV leukoencephalopathy
type: Class
IAO_0000115: A HIV encephalopathy that results_in inflammation located_in white matter of neuraxis, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom weakness, has_symptom paralysis, has_symptom vision loss, has_symptom impaired speech, and has_symptom cognitive deterioration.
has exact synonym: Human immunodefiency virus leukoencephalopathy (disorder)
has OBO namespace: disease_ontology
id: DOID:7555
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV leukoencephalopathy
annotated property: IAO_0000115
annotated target: A HIV encephalopathy that results_in inflammation located_in white matter of neuraxis, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom weakness, has_symptom paralysis, has_symptom vision loss, has_symptom impaired speech, and has_symptom cognitive deterioration.
type: ECO_0007638
has db xref: url:http://emedicine.medscape.com/article/1167145-overview
has db xref: url:http://en.wikipedia.org/wiki/Progressive_multifocal_leukoencephalopathy

obsolete HIV-associated lipodystrophy syndrome
type: Class
IAO_0000115: A lipodystrophy and is_a Human immunodeficiency virus infectious disease that is characterized by loss of subcutaneous fat, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. Anti-retroviral medications are also associated with the disease. The infection has_symptom fat loss in face, buttocks, arms, legs.
has OBO namespace: disease_ontology
id: DOID:810
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete HIV-associated lipodystrophy syndrome
annotated property: IAO_0000115
annotated target: A lipodystrophy and is_a Human immunodeficiency virus infectious disease that is characterized by loss of subcutaneous fat, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. Anti-retroviral medications are also associated with the disease. The infection has_symptom fat loss in face, buttocks, arms, legs.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Hiv-associated_lipodystrophy_syndrome

milker's nodule
type: Class
IAO_0000115: A viral infectious disease that results_in infection of cattle and humans, located_in skin, has_material_basis_in Pseudocowpox virus (Parapoxvirus pseudocowpox), which is transmitted_by contact with the infected cow teats, or transmitted_by fomites. The infection results_in_formation_of lesions on the fingers, hands, and forearms and has_symptom fever, has_symptom lymphangitis, and has_symptom lymphadenopathy.
has db xref: ICD10CM:B08.04
has db xref: ICD9CM:051.9
has db xref: MESH:D011213
has db xref: SNOMEDCT_US_2023_03_01:266193008
has db xref: UMLS_CUI:C0026143
has exact synonym: Milkers' node
has exact synonym: Paravaccinia
has exact synonym: milker nodule
has OBO namespace: disease_ontology
has related synonym: Pseudocowpox
id: DOID:8729
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: milker's nodule
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection of cattle and humans, located_in skin, has_material_basis_in Pseudocowpox virus (Parapoxvirus pseudocowpox), which is transmitted_by contact with the infected cow teats, or transmitted_by fomites. The infection results_in_formation_of lesions on the fingers, hands, and forearms and has_symptom fever, has_symptom lymphangitis, and has_symptom lymphadenopathy.
type: ECO_0007637
has db xref: url:http://www.cfsph.iastate.edu/FastFacts/pdfs/pseudocowpox_F.pdf
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC3945082/

contagious pustular dermatitis
type: Class
IAO_0000115: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Orf virus (Parapoxvirus orf), which is transmitted_by contact with infected or recently vaccinated animals, or transmitted_by fomites carrying the virus. The infection has_symptom lesions on the finger, hand, arm, face, and penis.
has db xref: ICD10CM:B08.02
has db xref: ICD9CM:051.2
has db xref: MESH:D004474
has db xref: SNOMEDCT_US_2023_03_01:74050005
has db xref: UMLS_CUI:C0013570
has exact synonym: Ecthyma contagiosum
has exact synonym: Ecthyma, Contagious
has exact synonym: Orf
has exact synonym: scabby mouth
has exact synonym: sheep pox
has exact synonym: thistle disease
has OBO namespace: disease_ontology
id: DOID:8771
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: contagious pustular dermatitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Orf virus (Parapoxvirus orf), which is transmitted_by contact with infected or recently vaccinated animals, or transmitted_by fomites carrying the virus. The infection has_symptom lesions on the finger, hand, arm, face, and penis.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Orf_%28disease%29
has db xref: url:http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5503a1.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK562191/

cowpox
type: Class
IAO_0000115: A viral infectious disease that results_in infection in rodents, cows, and humans, located_in skin, has_material_basis_in Cowpox virus (Orthopoxvirus cowpox), which is transmitted_by contact with an infected animal. The infection results_in_formation_of vesicopustular lesions on the hands or face.
has db xref: ICD10CM:B08.010
has db xref: ICD9CM:051.01
has db xref: MESH:D015605
has db xref: SNOMEDCT_US_2023_03_01:154344005
has db xref: UMLS_CUI:C0010232
has exact synonym: yaba
has OBO namespace: disease_ontology
id: DOID:8956
in subset: DO infectious disease slim
in subset: zoonotic infectious disease
broad match: ORDO:438279

Axiom
annotated source: cowpox
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection in rodents, cows, and humans, located_in skin, has_material_basis_in Cowpox virus (Orthopoxvirus cowpox), which is transmitted_by contact with an infected animal. The infection results_in_formation_of vesicopustular lesions on the hands or face.
type: ECO_0007645
has db xref: url:https://en.wikipedia.org/wiki/Cowpox
has db xref: url:https://pmc.ncbi.nlm.nih.gov/articles/PMC3945082/
has db xref: url:https://www.nejm.org/doi/10.1056/NEJMicm1702548?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov

leishmaniasis
type: Class
IAO_0000115: A parasitic protozoa infectious disease that involves infection caused by protozoan parasite of the genus Leishmania, which is transmitted by the bite of sand fly (subfamily Phlebotominae).
has alternative id: DOID:9136
has db xref: GARD:6881
has db xref: ICD10CM:B55
has db xref: ICD9CM:085
has db xref: MESH:D007896
has db xref: NCI:C34767
has db xref: ORDO:507
has db xref: SNOMEDCT_US_2023_03_01:266206004
has db xref: UMLS_CUI:C0023281
has OBO namespace: disease_ontology
has related synonym: Post Kala-Azar Dermal Leishmaniasis
has related synonym: Post-kala-azar dermal leishmaniasis
has related synonym: post-kala-azar dermal infectious disease by leishmaniasis
id: DOID:9065
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: leishmaniasis
annotated property: IAO_0000115
annotated target: A parasitic protozoa infectious disease that involves infection caused by protozoan parasite of the genus Leishmania, which is transmitted by the bite of sand fly (subfamily Phlebotominae).
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dpd/parasites/leishmania/factsht_leishmania.htm

cutaneous leishmaniasis
type: Class
subclass of: leishmaniasis
IAO_0000115: A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions.
has alternative id: DOID:13553
has alternative id: DOID:9110
has alternative id: DOID:9122
has alternative id: DOID:9167
has db xref: ICD10CM:B55.1
has db xref: MESH:D016773
has db xref: NCI:C34768
has db xref: SNOMEDCT_US_2023_03_01:240637006
has db xref: UMLS_CUI:C0023283
has exact synonym: Asian Desert Cutaneous Leishmaniasis
has exact synonym: Leproid leishmaniasis
has exact synonym: diffuse cutaneous leishmaniasis
has OBO namespace: disease_ontology
id: DOID:9111
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: cutaneous leishmaniasis
annotated property: IAO_0000115
annotated target: A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions.
type: ECO_0007637
has db xref: url:http://www.dpd.cdc.gov/dpdx/HTML/Leishmaniasis.htm

visceral leishmaniasis
type: Class
subclass of: leishmaniasis
IAO_0000115: A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver.
has db xref: ICD10CM:B55.0
has db xref: ICD9CM:085.0
has db xref: MESH:D007898
has db xref: MIM:608207
has db xref: MIM:611381
has db xref: MIM:611382
has db xref: NCI:C34771
has db xref: SNOMEDCT_US_2023_03_01:48115004
has db xref: UMLS_CUI:C0023290
has exact synonym: Infection by visceral leishmaniasis
has exact synonym: Kala-Azar
has OBO namespace: disease_ontology
id: DOID:9146
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease
comment: Xref MGI.

Axiom
annotated source: visceral leishmaniasis
annotated property: IAO_0000115
annotated target: A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Visceral_leishmaniasis
has db xref: url:http://www.dpd.cdc.gov/dpdx/HTML/Leishmaniasis.htm

mucocutaneous leishmaniasis
type: Class
subclass of: leishmaniasis
IAO_0000115: A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.
has db xref: ICD10CM:B55.2
has db xref: ICD9CM:085.5
has db xref: MESH:D007897
has db xref: SNOMEDCT_US_2023_03_01:721813000
has db xref: UMLS_CUI:C1328252
has exact synonym: American cutaneous leishmaniasis
has exact synonym: American mucocutaneous leishmaniasis
has exact synonym: Cutaneous leishmaniasis, American
has exact synonym: Mucocutaneous leishmaniasis, American
has exact synonym: New World cutaneous leishmaniasis
has OBO namespace: disease_ontology
id: DOID:9155
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: mucocutaneous leishmaniasis
annotated property: IAO_0000115
annotated target: A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.
type: ECO_0007645
has db xref: url:http://www.bmj.com/cgi/content/full/329/7470/842

monieziasis
type: Class
IAO_0000115: A parasitic helminthiasis infectious disease that involves zoonotic infection caused by Moniezia expansa, the common tapeworm of sheep.
has db xref: MESH:D008989
has db xref: UMLS_CUI:C0026414
has OBO namespace: disease_ontology
id: DOID:931
in subset: DO infectious disease slim
in subset: zoonotic infectious disease

Axiom
annotated source: monieziasis
annotated property: IAO_0000115
annotated target: A parasitic helminthiasis infectious disease that involves zoonotic infection caused by Moniezia expansa, the common tapeworm of sheep.
type: ECO_0007645
has db xref: url:https://www.ncbi.nlm.nih.gov/pubmed/15287174

obsolete Salmonella meningitis
type: Class
has OBO namespace: disease_ontology
id: DOID:9468
in subset: gram-negative bacterial infectious disease
in subset: zoonotic infectious disease
deprecated: true

Lassa fever
type: Class
IAO_0000115: A viral infectious disease that results_in infection, has_material_basis_in Lassa virus (Mammarenavirus lassaense), which is transmitted_by multimammate rat of the genus Mastomys. The infection has_symptom fever, has_symptom retrosternal pain, has_symptom sore throat, has_symptom back pain, has_symptom cough, has_symptom abdominal pain, has_symptom vomiting, has_symptom diarrhea, has_symptom conjunctivitis, has_symptom facial swelling, has_symptom proteinuria (protein in the urine), and has_symptom mucosal bleeding.
has db xref: ICD10CM:A96.2
has db xref: MESH:D007835
has db xref: NCI:C128418
has db xref: SNOMEDCT_US_2023_03_01:19065005
has db xref: UMLS_CUI:C0023092
has OBO namespace: disease_ontology
id: DOID:9537
in subset: DO infectious disease slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Lassa fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in infection, has_material_basis_in Lassa virus (Mammarenavirus lassaense), which is transmitted_by multimammate rat of the genus Mastomys. The infection has_symptom fever, has_symptom retrosternal pain, has_symptom sore throat, has_symptom back pain, has_symptom cough, has_symptom abdominal pain, has_symptom vomiting, has_symptom diarrhea, has_symptom conjunctivitis, has_symptom facial swelling, has_symptom proteinuria (protein in the urine), and has_symptom mucosal bleeding.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lassaf.htm

Venezuelan equine encephalitis
type: Class
IAO_0000115: A viral infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Venezuelan equine encephalitis virus (Alphavirus venezuelan), which is transmitted_by Culex mosquitoes. The infection has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom severe headache, has_symptom photophobia, and has_symptom myalgia in the legs and lumbosacral region.
has db xref: GARD:6355
has db xref: ICD10CM:A92.2
has db xref: ICD9CM:066.2
has db xref: MESH:D004685
has db xref: NCI:C35121
has db xref: SNOMEDCT_US_2023_03_01:89990001
has db xref: UMLS_CUI:C0014078
has OBO namespace: disease_ontology
has related synonym: Venezuelan equine fever
id: DOID:9584
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: Venezuelan equine encephalitis
annotated property: IAO_0000115
annotated target: A viral infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Venezuelan equine encephalitis virus (Alphavirus venezuelan), which is transmitted_by Culex mosquitoes. The infection has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom severe headache, has_symptom photophobia, and has_symptom myalgia in the legs and lumbosacral region.
type: ECO_0007637
has db xref: url:http://www.cdc.gov/ncidod/dvbid/arbor/arbdet.htm
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK559332/
has db xref: url:https://wwwnc.cdc.gov/eid/article/16/3/09-0970_article

obsolete equine encephalitis
type: Class
IAO_0000115: An Alphavirus infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Eastern equine encephalitis virus, has_material_basis_in Venezuelan equine encephalitis virus, or has_material_basis_in Western equine encephalomyelitis virus, which are transmitted_by moquito bite. The infection has_symptom fever, has_symptom headache, and has_symptom malaise.
has OBO namespace: disease_ontology
id: DOID:9585
in subset: zoonotic infectious disease
deprecated: true

Axiom
annotated source: obsolete equine encephalitis
annotated property: IAO_0000115
annotated target: An Alphavirus infectious disease that results_in inflammation located_in brain of horses and humans, has_material_basis_in Eastern equine encephalitis virus, has_material_basis_in Venezuelan equine encephalitis virus, or has_material_basis_in Western equine encephalomyelitis virus, which are transmitted_by moquito bite. The infection has_symptom fever, has_symptom headache, and has_symptom malaise.
has db xref: url:http://www.state.nj.us/agriculture/divisions/ah/diseases/equine_encephalomyelitis.html

babesiosis
type: Class
IAO_0000115: A parasitic protozoa infectious disease that has_symptom mild fevers and has_symptom anemia described as malaria-like symptoms caused by a protozoan of genus Babesia, which reproduce in red blood cells and cause hemolytic anemia. They are transmitted by Ixodid ticks or by blood transfusion. Babesiosis is a zoonotic disease.
has db xref: GARD:5878
has db xref: ICD10CM:B60.0
has db xref: ICD9CM:088.82
has db xref: MESH:D001404
has db xref: NCI:C84581
has db xref: SNOMEDCT_US_2023_03_01:187241002
has db xref: UMLS_CUI:C0004576
has exact synonym: Babesiasis
has exact synonym: Infection by babesia
has exact synonym: piroplasmosis
has OBO namespace: disease_ontology
id: DOID:9643
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: tick-borne infectious disease
in subset: zoonotic infectious disease

Axiom
annotated source: babesiosis
annotated property: IAO_0000115
annotated target: A parasitic protozoa infectious disease that has_symptom mild fevers and has_symptom anemia described as malaria-like symptoms caused by a protozoan of genus Babesia, which reproduce in red blood cells and cause hemolytic anemia. They are transmitted by Ixodid ticks or by blood transfusion. Babesiosis is a zoonotic disease.
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Babesiosis

yellow fever
type: Class
IAO_0000115: A viral infectious disease that results in infection, has_material_basis_in Yellow fever virus (Orthoflavivirus flavi), which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.
has alternative id: DOID:9683
has alternative id: DOID:9684
has db xref: GARD:7914
has db xref: ICD10CM:A95
has db xref: ICD9CM:060
has db xref: MESH:D015004
has db xref: NCI:C35547
has db xref: SNOMEDCT_US_2023_03_01:154345006
has db xref: UMLS_CUI:C0043395
has exact synonym: Sylvatic yellow fever
has exact synonym: Yellow fever, sylvan
has exact synonym: jungle yellow fever
has exact synonym: urban yellow fever
has OBO namespace: disease_ontology
id: DOID:9682
in subset: DO infectious disease slim
in subset: DO rare slim
in subset: NCIthesaurus
in subset: zoonotic infectious disease

Axiom
annotated source: yellow fever
annotated property: IAO_0000115
annotated target: A viral infectious disease that results in infection, has_material_basis_in Yellow fever virus (Orthoflavivirus flavi), which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.
type: ECO_0007637
type: ECO_0007638
has db xref: url:http://en.wikipedia.org/wiki/Yellow_fever
has db xref: url:https://www.cdc.gov/yellowfever/
has db xref: url:https://www.ncbi.nlm.nih.gov/books/NBK470425/
has db xref: url:https://www.who.int/news-room/fact-sheets/detail/yellow-fever