Symptom Ontology
type: Ontology
version IRI: symp.owl
has ontology root term: symptom
description: The Symptom Ontology has been developed as a standardized ontology for symptoms of human diseases.
license: https://creativecommons.org/publicdomain/zero/1.0/
date: 30:11:2022 09:11
default-namespace: symptoms
has_obo_format_version: 1.2
saved-by: lschriml

definition
type: AnnotationProperty

has ontology root term
type: AnnotationProperty

term replaced by
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

part_of
type: ObjectProperty
has_obo_namespace: symptoms
id: RO:0001901

cellulitis
type: Class
subclass of: musculoskeletal system symptom
definition: Cellulitis is a musculoskeletal system symptom characterized as a diffuse and especially subcutaneous inflammation of connective tissue.
has_obo_namespace: symptoms
id: SYMP:0000000
comment: doid/symp duplicate

Axiom
annotated source: cellulitis
annotated property: definition
annotated target: Cellulitis is a musculoskeletal system symptom characterized as a diffuse and especially subcutaneous inflammation of connective tissue.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cellulitis

abdominal cramp
type: Class
subclass of: abdominal symptom
has_exact_synonym: stomach cramp
has_obo_namespace: symptoms
id: SYMP:0000001

abdominal distention
type: Class
subclass of: abdominal symptom
has_obo_namespace: symptoms
id: SYMP:0000002

obsolete acute enteritis in newborns
type: Class
has_obo_namespace: symptoms
id: SYMP:0000003
deprecated: true

obsolete arrested moulting
type: Class
has_obo_namespace: symptoms
id: SYMP:0000004
deprecated: true

ataxia
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders.
has_exact_synonym: uncoordination
has_obo_namespace: symptoms
id: SYMP:0000005

Axiom
annotated source: ataxia
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ataxia

backache
type: Class
subclass of: pain
definition: A pain that is characterized by occurring in the lower back.
has_exact_synonym: back pain
has_obo_namespace: symptoms
id: SYMP:0000006

Axiom
annotated source: backache
annotated property: definition
annotated target: A pain that is characterized by occurring in the lower back.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=backache

bleeding
type: Class
subclass of: general symptom
definition: A general symptom that is characterized as an act, instance, or result of being bled or the process by which something is bled: as a the escape of blood from vessels.
has_obo_namespace: symptoms
id: SYMP:0000007

Axiom
annotated source: bleeding
annotated property: definition
annotated target: A general symptom that is characterized as an act, instance, or result of being bled or the process by which something is bled: as a the escape of blood from vessels.
database_cross_reference: url:http://www.merriam-webster.com/medlineplus/bleeding

blindness
type: Class
subclass of: vision symptom
has_obo_namespace: symptoms
id: SYMP:0000008
comment: doid/symp duplicate

blister
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a fluid-filled elevation of the epidermis.
has_obo_namespace: symptoms
id: SYMP:0000009

Axiom
annotated source: blister
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a fluid-filled elevation of the epidermis.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=blister

obsolete bloody diarrhea
type: Class
has_obo_namespace: symptoms
id: SYMP:0000010
deprecated: true

obsolete bloody exudate
type: Class
has_obo_namespace: symptoms
id: SYMP:0000011
deprecated: true

blurred vision
type: Class
subclass of: vision distortion
definition: A vision symptom that is characterized by a decreased clarity or sharpness in vision, which can be caused by eye conditions myopia or hyperopia.
has_obo_namespace: symptoms
id: SYMP:0000012

obsolete capillary leakage
type: Class
has_obo_namespace: symptoms
id: SYMP:0000013
deprecated: true

obsolete cardiomyocyte destruction
type: Class
has_obo_namespace: symptoms
id: SYMP:0000014
deprecated: true

giddiness
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000015

confusion
type: Class
subclass of: balance symptom
definition: A balance symptom that is characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively.
has_obo_namespace: symptoms
id: SYMP:0000016

Axiom
annotated source: confusion
annotated property: definition
annotated target: A balance symptom that is characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=confusion

crinkle
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000017

darkening of skin
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000018

deafness
type: Class
subclass of: ear symptom
has_obo_namespace: symptoms
id: SYMP:0000019

dehydration
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by an abnormal depletion of body fluids.
has_obo_namespace: symptoms
id: SYMP:0000020

Axiom
annotated source: dehydration
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by an abnormal depletion of body fluids.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dehydration

delirium
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a mental disturbance characterized by confusion, disordered speech, and hallucinations.
has_obo_namespace: symptoms
id: SYMP:0000021

Axiom
annotated source: delirium
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a mental disturbance characterized by confusion, disordered speech, and hallucinations.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=delirium

depression
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a chronic feeling of emptiness, sadness, or inability to feel pleasure that may appear to happen for no clear reason. Additionally one may experience feelings of hopelessness, pessimism, irritability, frustration, or restlessness, guilt, worthlessness and thoughts of death or suicide.
has_obo_namespace: symptoms
id: SYMP:0000022

Axiom
annotated source: depression
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a chronic feeling of emptiness, sadness, or inability to feel pleasure that may appear to happen for no clear reason. Additionally one may experience feelings of hopelessness, pessimism, irritability, frustration, or restlessness, guilt, worthlessness and thoughts of death or suicide.
database_cross_reference: url:https://www.medicalnewstoday.com/articles/8933
database_cross_reference: url:https://www.nimh.nih.gov/health/topics/depression

disorientation
type: Class
subclass of: confusion
definition: A confusion that is characterized by an usually transient state of confusion especially as to time, place, or identity; often as a result of disease or drugs.
has_obo_namespace: symptoms
id: SYMP:0000023

Axiom
annotated source: disorientation
annotated property: definition
annotated target: A confusion that is characterized by an usually transient state of confusion especially as to time, place, or identity; often as a result of disease or drugs.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=disorientation

drowsiness
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a feeling of being more sleepy than normal during the day. People who are drowsy may fall asleep in when they do not want to or at times which can lead to safety concerns.
has_exact_synonym: drowsy
has_exact_synonym: somnolence
has_obo_namespace: symptoms
id: SYMP:0000024

Axiom
annotated source: drowsiness
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a feeling of being more sleepy than normal during the day. People who are drowsy may fall asleep in when they do not want to or at times which can lead to safety concerns.
database_cross_reference: url:https://medlineplus.gov/ency/article/003208.htm

dry cough
type: Class
subclass of: cough
definition: A cough that is characterized by a lack of accompanied phlegm production.
has_exact_synonym: nonproductive cough
has_obo_namespace: symptoms
id: SYMP:0000025

Axiom
annotated source: dry cough
annotated property: has_exact_synonym
annotated target: nonproductive cough
database_cross_reference: url:https://www.healthline.com/health/dry-cough

obsolete epidermal proliferation
type: Class
has_obo_namespace: symptoms
id: SYMP:0000026
deprecated: true

obsolete excess mucus in bronchi
type: Class
has_obo_namespace: symptoms
id: SYMP:0000027
deprecated: true

obsolete exophthalmia
type: Class
has_exact_synonym: abnormal protrusion of the eyeball
has_obo_namespace: symptoms
id: SYMP:0000028
deprecated: true

obsolete feather loss
type: Class
has_obo_namespace: symptoms
id: SYMP:0000029
deprecated: true

paralysis
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a complete or partial loss of function especially when involving the power of motion or of sensation in any part of the body.
has_obo_namespace: symptoms
id: SYMP:0000030

Axiom
annotated source: paralysis
annotated property: definition
annotated target: A nervous system symptom that is characterized by a complete or partial loss of function especially when involving the power of motion or of sensation in any part of the body.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=paralysis

obsolete flaccid limb paralysis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000031
deprecated: true

flaccidity
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000032

flat keratotic capsule
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000033

obsolete fluid in pericardial sac
type: Class
has_obo_namespace: symptoms
id: SYMP:0000034
deprecated: true

obsolete fragile bones
type: Class
has_obo_namespace: symptoms
id: SYMP:0000035
deprecated: true

hemorrhagic gastroenteritis
type: Class
subclass of: gastroenteritis
has_exact_synonym: haemorrhagic gastroenteritis
has_obo_namespace: symptoms
id: SYMP:0000036

obsolete catarrhal enteritis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000037
deprecated: true

dyspneic enteritis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by being short or breath or out of air (dyspnea), with inflammation of the small intestine (enteritis).
has_obo_namespace: symptoms
id: SYMP:0000038

Axiom
annotated source: dyspneic enteritis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by being short or breath or out of air (dyspnea), with inflammation of the small intestine (enteritis).
database_cross_reference: url:https://medlineplus.gov/ency/article/001149.htm
database_cross_reference: url:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/dyspnea

enteritis
type: Class
subclass of: digestive system symptom
definition: Enteritis is a digestive system symptom involving the inflammation of the small intestines and especially of the human ileum.
has_obo_namespace: symptoms
id: SYMP:0000039

Axiom
annotated source: enteritis
annotated property: definition
annotated target: Enteritis is a digestive system symptom involving the inflammation of the small intestines and especially of the human ileum.
database_cross_reference: url:http://en.wikipedia.org/wiki/Enteritis
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=enteritis

hematuria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the presence of blood or blood cells in the urine.
has_obo_namespace: symptoms
id: SYMP:0000040

Axiom
annotated source: hematuria
annotated property: definition
annotated target: A urinary system symptom that is characterized by the presence of blood or blood cells in the urine.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hematuria

hemorrhage
type: Class
subclass of: cardiovascular system symptom
definition: A cardiovascular system symptom that is characterized by an acute loss of blood from a damaged blood vessel.
has_obo_namespace: symptoms
id: SYMP:0000041

Axiom
annotated source: hemorrhage
annotated property: definition
annotated target: A cardiovascular system symptom that is characterized by an acute loss of blood from a damaged blood vessel.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK542273/

obsolete hemorrhagic enteritis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000042
deprecated: true

obsolete hemorrhagic meningitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000043
deprecated: true

obsolete hemorrhagic thoracic lymphadenitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000044
deprecated: true

hepatic necrosis
type: Class
subclass of: liver symptom
has_obo_namespace: symptoms
id: SYMP:0000045

hepatitis
type: Class
subclass of: liver symptom
has_obo_namespace: symptoms
id: SYMP:0000046
comment: doid/symp duplicate

hepatosplenomegaly
type: Class
subclass of: spleen symptom
subclass of: liver symptom
has_obo_namespace: symptoms
id: SYMP:0000047

obsolete high fever
type: Class
has_obo_namespace: symptoms
id: SYMP:0000048
deprecated: true

obsolete hind limb paralysis
type: Class
has_exact_synonym: hindlimb paralysis
has_obo_namespace: symptoms
id: SYMP:0000049
deprecated: true

obsolete hunched posture
type: Class
has_obo_namespace: symptoms
id: SYMP:0000050
deprecated: true

hydrocephalus
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000051
comment: doid/symp duplicate

obsolete hyperemic liver
type: Class
has_obo_namespace: symptoms
id: SYMP:0000052
deprecated: true

obsolete hyperemic spleen
type: Class
has_obo_namespace: symptoms
id: SYMP:0000053
deprecated: true

hypergammaglobulinemia
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000054

obsolete hyperkeratotic plaques of surface of foot
type: Class
has_obo_namespace: symptoms
id: SYMP:0000055
deprecated: true

hyperpigmentation
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an excess pigmentation in a bodily part or tissue, as the skin.
has_obo_namespace: symptoms
id: SYMP:0000056

Axiom
annotated source: hyperpigmentation
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an excess pigmentation in a bodily part or tissue, as the skin.

obsolete hyperplastic alveolar nodules
type: Class
has_exact_synonym: han
has_obo_namespace: symptoms
id: SYMP:0000057
deprecated: true

hyperreflexia
type: Class
subclass of: reflex symptom
has_obo_namespace: symptoms
id: SYMP:0000058

hypotension
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000059

obsolete ill-thrift
type: Class
has_obo_namespace: symptoms
id: SYMP:0000060
deprecated: true

inflammation
type: Class
subclass of: general symptom
definition: Inflammation is a general symptom where there is a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue.
has_obo_namespace: symptoms
id: SYMP:0000061

Axiom
annotated source: inflammation
annotated property: definition
annotated target: Inflammation is a general symptom where there is a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=inflammation

obsolete inflammation of meninges
type: Class
has_obo_namespace: symptoms
id: SYMP:0000062
deprecated: true

intestinal hemorrhage
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000063

joint pain
type: Class
subclass of: pain
definition: A pain that is characterized by a pain situated, or occurring, in or around a joint.
has_exact_synonym: arthralgia
has_exact_synonym: arthromyalgia
has_obo_namespace: symptoms
id: SYMP:0000064

Axiom
annotated source: joint pain
annotated property: definition
annotated target: A pain that is characterized by a pain situated, or occurring, in or around a joint.
database_cross_reference: url:https://medlineplus.gov/ency/article/003261.htm

obsolete joint swelling
type: Class
has_obo_namespace: symptoms
id: SYMP:0000065
deprecated: true

keratotic nodules of the skin
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000066

obsolete lameness
type: Class
has_obo_namespace: symptoms
id: SYMP:0000067
deprecated: true

laryngitis
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000068
comment: doid/symp duplicate

laryngotracheitis
type: Class
subclass of: throat symptom
has_exact_synonym: larynx and trachea inflammation
has_obo_namespace: symptoms
id: SYMP:0000069
comment: doid/symp duplicate

lesions in myocardium
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000070

obsolete lesions in respiratory tract
type: Class
has_obo_namespace: symptoms
id: SYMP:0000071
deprecated: true

obsolete lesions in spleen
type: Class
has_obo_namespace: symptoms
id: SYMP:0000072
deprecated: true

obsolete lesions in thymus
type: Class
has_obo_namespace: symptoms
id: SYMP:0000073
deprecated: true

obsolete lesions in swim bladder
type: Class
has_obo_namespace: symptoms
id: SYMP:0000074
deprecated: true

lethargy
type: Class
subclass of: fatigue
definition: A fatigue that is characterized by abnormal drowsiness.
has_obo_namespace: symptoms
id: SYMP:0000075

Axiom
annotated source: lethargy
annotated property: definition
annotated target: A fatigue that is characterized by abnormal drowsiness.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=lethargy

listlessness
type: Class
subclass of: general symptom
has_exact_synonym: languid
has_obo_namespace: symptoms
id: SYMP:0000076

obsolete localized cutaneous lesions
type: Class
has_obo_namespace: symptoms
id: SYMP:0000077
deprecated: true

obsolete loose droppings
type: Class
has_obo_namespace: symptoms
id: SYMP:0000078
deprecated: true

coordination symptom
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by the harmonious functioning of interrelated organs and body parts; in particular the working together of muscle groups in the execution of complicated movements.
has_obo_namespace: symptoms
id: SYMP:0000079

Axiom
annotated source: coordination symptom
annotated property: definition
annotated target: A nervous system symptom that is characterized by the harmonious functioning of interrelated organs and body parts; in particular the working together of muscle groups in the execution of complicated movements.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/coordinations

obsolete loss of coordination
type: Class
has_obo_namespace: symptoms
id: SYMP:0000080
deprecated: true

obsolete low grade fever
type: Class
has_obo_namespace: symptoms
id: SYMP:0000081
deprecated: true

lesions in lung
type: Class
subclass of: respiratory system and chest symptom
has_obo_namespace: symptoms
id: SYMP:0000082

lymphangitis
type: Class
subclass of: lymphatic system symptom
has_obo_namespace: symptoms
id: SYMP:0000083
comment: doid/symp duplicate

lymphoblastoma
type: Class
subclass of: lymphatic system symptom
has_obo_namespace: symptoms
id: SYMP:0000084

obsolete lymphocytic hyperplasia
type: Class
has_obo_namespace: symptoms
id: SYMP:0000085
deprecated: true

lymphopenia
type: Class
subclass of: lymphatic system symptom
has_obo_namespace: symptoms
id: SYMP:0000086
comment: doid/symp duplicate

massive hepatic necrosis
type: Class
subclass of: hepatic necrosis
has_obo_namespace: symptoms
id: SYMP:0000087

obsolete massive lymphadenopathy
type: Class
has_obo_namespace: symptoms
id: SYMP:0000088
deprecated: true

meningoencephalitis
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an inflammation of the brain and meninges.
has_obo_namespace: symptoms
id: SYMP:0000089
comment: doid/symp duplicate

Axiom
annotated source: meningoencephalitis
annotated property: definition
annotated target: A nervous system symptom that is characterized by an inflammation of the brain and meninges.

encephalitis
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by inflammation of the brain tissue, which is typically caused by a viral infection, but it may also be caused by bacterial or parasitic infections, cancer, or certain drugs or toxins.
has_obo_namespace: symptoms
id: SYMP:0000090
comment: doid/symp duplicate

Axiom
annotated source: encephalitis
annotated property: definition
annotated target: A nervous system symptom that is characterized by inflammation of the brain tissue, which is typically caused by a viral infection, but it may also be caused by bacterial or parasitic infections, cancer, or certain drugs or toxins.
database_cross_reference: url:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/encephalitis

mild encephalitis
type: Class
subclass of: encephalitis
definition: An encephalitis that is not intense (not severe).
has_obo_namespace: symptoms
id: SYMP:0000091

Axiom
annotated source: mild encephalitis
annotated property: definition
annotated target: An encephalitis that is not intense (not severe).
database_cross_reference: url:https://www.macmillandictionary.com/us/dictionary/american/mild_1

skin lesion
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an abnormal change in structure of the skin that is especially circumscribed and well defined due to injury or disease.
has_obo_namespace: symptoms
id: SYMP:0000092

Axiom
annotated source: skin lesion
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an abnormal change in structure of the skin that is especially circumscribed and well defined due to injury or disease.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=lesion

muscle cramp
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000093

muscle weakness
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000094

myocarditis
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000095
comment: doid/symp duplicate

obsolete nasal discharge
type: Class
has_obo_namespace: symptoms
id: SYMP:0000096
deprecated: true

obsolete neck swelling
type: Class
has_obo_namespace: symptoms
id: SYMP:0000097
deprecated: true

nephritis
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the acute or chronic inflammation of the kidney affecting the structure (as of the glomerulus or parenchyma) and caused by infection, a degenerative process, or vascular disease.
has_obo_namespace: symptoms
id: SYMP:0000098
comment: doid/symp duplicate

Axiom
annotated source: nephritis
annotated property: definition
annotated target: A urinary system symptom that is characterized by the acute or chronic inflammation of the kidney affecting the structure (as of the glomerulus or parenchyma) and caused by infection, a degenerative process, or vascular disease.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=nephritis

pain
type: Class
subclass of: sensation perception
definition: A sensation perception that is characterized by an unpleasant sensation that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual, confined to one area or spread over the entire body.
has_obo_namespace: symptoms
id: SYMP:0000099

Axiom
annotated source: pain
annotated property: definition
annotated target: A sensation perception that is characterized by an unpleasant sensation that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual, confined to one area or spread over the entire body.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

lesions in pancreas
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000100

obsolete partial paralysis
type: Class
has_exact_synonym: paresis
has_obo_namespace: symptoms
id: SYMP:0000101
deprecated: true

peritonitis
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an inflammation of the peritoneum.
has_obo_namespace: symptoms
id: SYMP:0000102
comment: doid/symp duplicate

Axiom
annotated source: peritonitis
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an inflammation of the peritoneum.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=peritonitis

obsolete persistent lymphocytosis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000103
deprecated: true

obsolete petechial hemorrhages
type: Class
has_obo_namespace: symptoms
id: SYMP:0000104
deprecated: true

obsolete photosensitivity
type: Class
has_obo_namespace: symptoms
id: SYMP:0000105
deprecated: true

plasmacytosis
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000106

pleural effusion
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an exudation of fluid from the blood or lymph into a pleural cavity.
has_obo_namespace: symptoms
id: SYMP:0000107

Axiom
annotated source: pleural effusion
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an exudation of fluid from the blood or lymph into a pleural cavity.

obsolete portal hepatitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000108
deprecated: true

mouth papules
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000109

obsolete proliferative mouth papules
type: Class
has_obo_namespace: symptoms
id: SYMP:0000110
deprecated: true

obsolete proliferative skin lesions
type: Class
has_obo_namespace: symptoms
id: SYMP:0000111
deprecated: true

tracheitis
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000112
comment: doid/symp duplicate

obsolete proliferative tracheitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000113
deprecated: true

thrombocytopenia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000114
comment: doid/symp duplicate

obsolete prolonged thrombocytopenia
type: Class
has_obo_namespace: symptoms
id: SYMP:0000115
deprecated: true

prostration
type: Class
subclass of: general symptom
definition: Prostration is a general symptom characterized by complete physical or mental exhaustion.
has_obo_namespace: symptoms
id: SYMP:0000116

Axiom
annotated source: prostration
annotated property: definition
annotated target: Prostration is a general symptom characterized by complete physical or mental exhaustion.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=prostration

obsolete pustular skin lesions
type: Class
has_obo_namespace: symptoms
id: SYMP:0000117
deprecated: true

rales
type: Class
subclass of: abnormal chest sound
definition: An abnormal chest sound that is characterized by the clicking, rattling, or crackling noises heard on auscultation of (listening to) the lung with a stethoscope during inhalation. The sounds are caused by the 'popping open' of small airways and alveoli collapsed by fluid, exudate, or lack of aeration during expiration. The word 'rales' derives from the French word rale meaning 'rattle'. Rales can be heard in patients with pneumonia, atelectasis, pulmonary fibrosis, acute bronchitis, or bronchiectasis. Pulmonary edema secondary to left-sided congestive heart failure can also cause rales.
has_exact_synonym: crackles
has_exact_synonym: crepitations
has_obo_namespace: symptoms
id: SYMP:0000118

Axiom
annotated source: rales
annotated property: definition
annotated target: An abnormal chest sound that is characterized by the clicking, rattling, or crackling noises heard on auscultation of (listening to) the lung with a stethoscope during inhalation. The sounds are caused by the 'popping open' of small airways and alveoli collapsed by fluid, exudate, or lack of aeration during expiration. The word 'rales' derives from the French word rale meaning 'rattle'. Rales can be heard in patients with pneumonia, atelectasis, pulmonary fibrosis, acute bronchitis, or bronchiectasis. Pulmonary edema secondary to left-sided congestive heart failure can also cause rales.
database_cross_reference: url:http://en.wikipedia.org/wiki/Rales

obsolete reddening
type: Class
has_obo_namespace: symptoms
id: SYMP:0000119
deprecated: true

obsolete retinal inflammation
type: Class
has_obo_namespace: symptoms
id: SYMP:0000120
deprecated: true

obsolete rhinitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000121
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

obsolete salivary gland swelling
type: Class
has_obo_namespace: symptoms
id: SYMP:0000122
deprecated: true

obsolete sclerodermoid plaques
type: Class
has_obo_namespace: symptoms
id: SYMP:0000123
deprecated: true

seizure
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000124

liver inflammation
type: Class
subclass of: liver symptom
has_obo_namespace: symptoms
id: SYMP:0000125

obsolete self-limiting liver inflammation
type: Class
has_obo_namespace: symptoms
id: SYMP:0000126
deprecated: true

severe backache
type: Class
subclass of: backache
has_exact_synonym: intense back pain
has_obo_namespace: symptoms
id: SYMP:0000127

conjunctivitis
type: Class
subclass of: conjunctiva symptom
has_obo_namespace: symptoms
id: SYMP:0000128
comment: doid/symp duplicate

severe conjunctivitis
type: Class
subclass of: conjunctivitis
has_obo_namespace: symptoms
id: SYMP:0000129

severe headache
type: Class
subclass of: headache
has_obo_namespace: symptoms
id: SYMP:0000130

severe joint pain
type: Class
subclass of: joint pain
definition: A joint pain that is characterized by a pain situated, or occurring, in or around a joint that is intense (severe).
has_exact_synonym: intense join pain
has_obo_namespace: symptoms
id: SYMP:0000131

Axiom
annotated source: severe joint pain
annotated property: definition
annotated target: A joint pain that is characterized by a pain situated, or occurring, in or around a joint that is intense (severe).
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/severe

necrosis
type: Class
subclass of: general symptom
definition: Necrosis is a general symptom where death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease).
has_obo_namespace: symptoms
id: SYMP:0000132

Axiom
annotated source: necrosis
annotated property: definition
annotated target: Necrosis is a general symptom where death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=necrosis

severe necrosis
type: Class
subclass of: necrosis
has_obo_namespace: symptoms
id: SYMP:0000133

sinusitis
type: Class
subclass of: nose symptom
has_obo_namespace: symptoms
id: SYMP:0000134
comment: doid/symp duplicate

obsolete skin papules
type: Class
has_obo_namespace: symptoms
id: SYMP:0000135
deprecated: true

skin ulcer
type: Class
subclass of: skin lesion
definition: A skin lesion that is characterized by a break in skin with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus.
has_obo_namespace: symptoms
id: SYMP:0000136

Axiom
annotated source: skin ulcer
annotated property: definition
annotated target: A skin lesion that is characterized by a break in skin with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ulcer

obsolete slight cough
type: Class
has_obo_namespace: symptoms
id: SYMP:0000137
deprecated: true

obsolete slight pyrexia
type: Class
has_obo_namespace: symptoms
id: SYMP:0000138
deprecated: true

sneezing
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a sudden violent spasmodic audible expiration of breath through the nose and mouth especially as a reflex act following irritation of the nasal mucous membrane.
has_obo_namespace: symptoms
id: SYMP:0000139

Axiom
annotated source: sneezing
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a sudden violent spasmodic audible expiration of breath through the nose and mouth especially as a reflex act following irritation of the nasal mucous membrane.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sneezing

obsolete spastic paralysis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000140
deprecated: true

spasticity
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an abnormal increase in muscle tone or stiffness of muscle, which might interfere with movement, speech, or be associated with discomfort or pain.
has_obo_namespace: symptoms
id: SYMP:0000141

Axiom
annotated source: spasticity
annotated property: definition
annotated target: A nervous system symptom that is characterized by an abnormal increase in muscle tone or stiffness of muscle, which might interfere with movement, speech, or be associated with discomfort or pain.
database_cross_reference: url:https://www.ninds.nih.gov/health-information/disorders/spasticity

obsolete spleen hemorrhages
type: Class
has_obo_namespace: symptoms
id: SYMP:0000142
deprecated: true

obsolete spleen infiltrates
type: Class
has_obo_namespace: symptoms
id: SYMP:0000143
deprecated: true

obsolete bronchopneumonia
type: Class
definition: A pneumonia that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs
term replaced by: bronchiole inflammation
has_exact_synonym: bronchial pneumonia
has_exact_synonym: lobular pneumonia
has_obo_namespace: symptoms
id: SYMP:0000144
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete bronchopneumonia
annotated property: definition
annotated target: A pneumonia that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs
database_cross_reference: url:https://en.wikipedia.org/wiki/Bronchopneumonia

obsolete splitting of tissues
type: Class
has_obo_namespace: symptoms
id: SYMP:0000145
deprecated: true

feces and droppings symptom
type: Class
subclass of: digestive system symptom
has_exact_synonym: fecal
has_obo_namespace: symptoms
id: SYMP:0000146

steatorrhea
type: Class
subclass of: feces and droppings symptom
has_obo_namespace: symptoms
id: SYMP:0000147
comment: doid/symp duplicate

obsolete sudden onset of fever
type: Class
has_obo_namespace: symptoms
id: SYMP:0000148
deprecated: true

obsolete sudden onset of severe chills
type: Class
has_obo_namespace: symptoms
id: SYMP:0000149
deprecated: true

obsolete swollen cervical lymphnodes
type: Class
has_obo_namespace: symptoms
id: SYMP:0000150
deprecated: true

obsolete systemic infection
type: Class
has_obo_namespace: symptoms
id: SYMP:0000151
deprecated: true

obsolete systemic necrosis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000152
deprecated: true

vasculitis
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000153
comment: doid/symp duplicate

obsolete systemic vasculitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000154
deprecated: true

obsolete tarry droppings
type: Class
has_obo_namespace: symptoms
id: SYMP:0000155
deprecated: true

thirst
type: Class
subclass of: general symptom
definition: Thirst is a general symptom characterized by a sensation of dryness in the mouth and throat associated with a desire for liquids.
has_obo_namespace: symptoms
id: SYMP:0000156

Axiom
annotated source: thirst
annotated property: definition
annotated target: Thirst is a general symptom characterized by a sensation of dryness in the mouth and throat associated with a desire for liquids.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=thirst

thymus symptom
type: Class
subclass of: immune system symptom
has_obo_namespace: symptoms
id: SYMP:0000157

spleen symptom
type: Class
subclass of: immune system symptom
has_obo_namespace: symptoms
id: SYMP:0000158

obsolete thymus atrophy
type: Class
has_obo_namespace: symptoms
id: SYMP:0000159
deprecated: true

tracheobronchitis
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000160

obsolete transient fever
type: Class
has_obo_namespace: symptoms
id: SYMP:0000161
deprecated: true

tremor
type: Class
subclass of: general symptom
definition: Tremor is a generial symptom characterized by a trembling or shaking usually from physical weakness, emotional stress, or disease.
has_obo_namespace: symptoms
id: SYMP:0000162

Axiom
annotated source: tremor
annotated property: definition
annotated target: Tremor is a generial symptom characterized by a trembling or shaking usually from physical weakness, emotional stress, or disease.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tremor

obsolete ulcerative dermal vesicles
type: Class
has_obo_namespace: symptoms
id: SYMP:0000163
deprecated: true

incoordination
type: Class
subclass of: coordination symptom
definition: A coordination symptom that is characterized by a loss of complicated body movements, which may be caused by disease, injury, or toxins.
has_exact_synonym: lack of coordination
has_obo_namespace: symptoms
id: SYMP:0000164

Axiom
annotated source: incoordination
annotated property: definition
annotated target: A coordination symptom that is characterized by a loss of complicated body movements, which may be caused by disease, injury, or toxins.
database_cross_reference: url:https://www.merckmanuals.com/home/brain,-spinal-cord,-and-nerve-disorders/movement-disorders/coordination-disorders

obsolete upper respiratory distress
type: Class
has_obo_namespace: symptoms
id: SYMP:0000165
deprecated: true

obsolete vascular lesions
type: Class
has_obo_namespace: symptoms
id: SYMP:0000166
deprecated: true

obsolete vascular necrosis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000167
deprecated: true

obsolete vein swelling
type: Class
has_obo_namespace: symptoms
id: SYMP:0000168
deprecated: true

obsolete vesicles on feet
type: Class
has_obo_namespace: symptoms
id: SYMP:0000169
deprecated: true

obsolete vesicles on hoof corona
type: Class
has_obo_namespace: symptoms
id: SYMP:0000170
deprecated: true

obsolete vesicles on mouth
type: Class
has_obo_namespace: symptoms
id: SYMP:0000171
deprecated: true

obsolete vesicles on teats
type: Class
has_obo_namespace: symptoms
id: SYMP:0000172
deprecated: true

obsolete vesicular lesions on lip border
type: Class
has_exact_synonym: cold sore
has_obo_namespace: symptoms
id: SYMP:0000173
deprecated: true

wasting
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by the unintended loss of weight and lean body tissue characteristic of many diseases (as cancer, tuberculosis, and AIDS).
has_obo_namespace: symptoms
id: SYMP:0000174

Axiom
annotated source: wasting
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by the unintended loss of weight and lean body tissue characteristic of many diseases (as cancer, tuberculosis, and AIDS).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=wasting

obsolete watery diarrhea
type: Class
has_obo_namespace: symptoms
id: SYMP:0000175
deprecated: true

obsolete watery ocular discharge
type: Class
has_obo_namespace: symptoms
id: SYMP:0000176
deprecated: true

weakness
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000177

weight loss
type: Class
subclass of: weight symptom
definition: A weight symptom that is characterized by a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can either occur unintentionally because of malnourishment or an underlying disease.
has_alternative_id: SYMP:0000476
database_cross_reference: ICD9CM_2005:783.21
database_cross_reference: UMLS_CUI:C0043096
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1605347
has_exact_synonym: loss of weight
has_obo_namespace: symptoms
id: SYMP:0000178

Axiom
annotated source: weight loss
annotated property: definition
annotated target: A weight symptom that is characterized by a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can either occur unintentionally because of malnourishment or an underlying disease.
database_cross_reference: url:https://en.wikipedia.org/wiki/Weight_loss

obsolete wet droppings
type: Class
has_obo_namespace: symptoms
id: SYMP:0000179
deprecated: true

liver symptom
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000180

obsolete yellow liver
type: Class
has_obo_namespace: symptoms
id: SYMP:0000181
deprecated: true

bubo
type: Class
subclass of: lymphadenitis
has_exact_synonym: buboes
has_obo_namespace: symptoms
id: SYMP:0000182

muscle symptom
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000183

change in skin color
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000184

weariness
type: Class
subclass of: fatigue
definition: A fatigue that is characterized by a feeling of exhaustion in strength, endurance, and vigor.
has_obo_namespace: symptoms
id: SYMP:0000185

Axiom
annotated source: weariness
annotated property: definition
annotated target: A fatigue that is characterized by a feeling of exhaustion in strength, endurance, and vigor.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/weary

exhaustion
type: Class
subclass of: fatigue
definition: A fatigue that is characterized by a feeling of weariness (bodily or mental) or feeling of weakness. Exhaustion is a shorter-lived form of fatigue that can be experienced emotionally, mentally, and physically.
has_obo_namespace: symptoms
id: SYMP:0000186

Axiom
annotated source: exhaustion
annotated property: definition
annotated target: A fatigue that is characterized by a feeling of weariness (bodily or mental) or feeling of weakness. Exhaustion is a shorter-lived form of fatigue that can be experienced emotionally, mentally, and physically.
database_cross_reference: url:https://wellteq.co/insights/mental-health/fatigue-burnout-and-exhaustion-whats-the-difference
database_cross_reference: url:https://www.dictionary.com/browse/fatigue

tiredness
type: Class
subclass of: fatigue
definition: A fatigue that is characterized by a feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue.
has_obo_namespace: symptoms
id: SYMP:0000187

Axiom
annotated source: tiredness
annotated property: definition
annotated target: A fatigue that is characterized by a feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue.
database_cross_reference: url:https://www.medicinenet.com/tired/definition.htm

abdominal discomfort
type: Class
subclass of: abdominal symptom
has_obo_namespace: symptoms
id: SYMP:0000188

postural reaction
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000189

wheelbarrowing
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000190

obsolete hemistanding
type: Class
has_obo_namespace: symptoms
id: SYMP:0000191
deprecated: true

obsolete hemiwalking
type: Class
has_obo_namespace: symptoms
id: SYMP:0000192
deprecated: true

hopping
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000193

conscious proprioception
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000194

abnormal hemiwalking hemistanding
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000195

reproductive system symptom
type: Class
subclass of: symptom
has_obo_namespace: symptoms
id: SYMP:0000196

abortion
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by the expulsion of a fetus at any time before completion of pregnancy and is often due to infection.
has_exact_synonym: infectious abortion
has_obo_namespace: symptoms
id: SYMP:0000197

Axiom
annotated source: abortion
annotated property: definition
annotated target: A reproductive system symptom that is characterized by the expulsion of a fetus at any time before completion of pregnancy and is often due to infection.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=abortion

miscarriage
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by the spontaneous expulsion of a human fetus before it is viable and especially between the 12th and 28th weeks of gestation.
has_obo_namespace: symptoms
id: SYMP:0000198

Axiom
annotated source: miscarriage
annotated property: definition
annotated target: A reproductive system symptom that is characterized by the spontaneous expulsion of a human fetus before it is viable and especially between the 12th and 28th weeks of gestation.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=miscarriage

spontaneous abortion
type: Class
subclass of: abortion
definition: An abortion that is characterized by the natural occurring expulsion of a nonviable fetus.
has_obo_namespace: symptoms
id: SYMP:0000199

Axiom
annotated source: spontaneous abortion
annotated property: definition
annotated target: An abortion that is characterized by the natural occurring expulsion of a nonviable fetus.

acute arthritis
type: Class
subclass of: arthritis
has_obo_namespace: symptoms
id: SYMP:0000200

acute meningoencephalitis
type: Class
subclass of: meningoencephalitis
definition: A meningoencephalitis that is characterized by a severe and sudden onset.
has_obo_namespace: symptoms
id: SYMP:0000201

Axiom
annotated source: acute meningoencephalitis
annotated property: definition
annotated target: A meningoencephalitis that is characterized by a severe and sudden onset.
database_cross_reference: url:https://medlineplus.gov/ency/imagepages/18126.htm

acute painful vision loss
type: Class
subclass of: pain
has_obo_namespace: symptoms
id: SYMP:0000202

obsolete acute respiratory distress
type: Class
has_obo_namespace: symptoms
id: SYMP:0000203
deprecated: true

obsolete acute suppurative lesions
type: Class
has_obo_namespace: symptoms
id: SYMP:0000204
deprecated: true

salivary gland symptom
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000205

acute suppurative parotiditis
type: Class
subclass of: salivary gland symptom
has_obo_namespace: symptoms
id: SYMP:0000206

afebrile
type: Class
subclass of: fever
definition: A fever that is characterized by the state of being free from fever.
has_obo_namespace: symptoms
id: SYMP:0000207

Axiom
annotated source: afebrile
annotated property: definition
annotated target: A fever that is characterized by the state of being free from fever.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=afebrile

anemia
type: Class
subclass of: hemic system symptom
has_exact_synonym: anaemia
has_obo_namespace: symptoms
id: SYMP:0000208
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

ischemia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000209

photophobia
type: Class
subclass of: light sensitivity
has_exact_synonym: light intolerance
has_obo_namespace: symptoms
id: SYMP:0000210

asthenopia
type: Class
subclass of: eye symptom
has_exact_synonym: eye weakness
has_exact_synonym: rapid eye fatigue
has_obo_namespace: symptoms
id: SYMP:0000211
comment: doid/symp duplicate

eye strain
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000212

agraphia
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a pathological loss of the ability to write.
has_exact_synonym: inability to write
has_obo_namespace: symptoms
id: SYMP:0000213

Axiom
annotated source: agraphia
annotated property: definition
annotated target: An aphasia that is characterized by a pathological loss of the ability to write.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=agraphia

anomia
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a severe problem with recalling words or names.
has_exact_synonym: amnesic aphasia
has_exact_synonym: amnestic aphasia
has_exact_synonym: anomic aphasia
has_exact_synonym: inability to name objects
has_exact_synonym: nominal aphasia
has_obo_namespace: symptoms
id: SYMP:0000214
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

Axiom
annotated source: anomia
annotated property: definition
annotated target: An aphasia that is characterized by a severe problem with recalling words or names.
database_cross_reference: url:http://en.wikipedia.org/wiki/Anomia

inability to comprehend speech
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a loss of ability to comprehend speech.
has_obo_namespace: symptoms
id: SYMP:0000215

Axiom
annotated source: inability to comprehend speech
annotated property: definition
annotated target: An aphasia that is characterized by a loss of ability to comprehend speech.
database_cross_reference: url:https://www.healthline.com/health/aphasia#causes
database_cross_reference: url:https://www.nidcd.nih.gov/health/aphasia

inability to speak
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a loss of ability to speak.
has_obo_namespace: symptoms
id: SYMP:0000216

Axiom
annotated source: inability to speak
annotated property: definition
annotated target: An aphasia that is characterized by a loss of ability to speak.
database_cross_reference: url:https://www.healthline.com/health/aphasia#causes
database_cross_reference: url:https://www.nidcd.nih.gov/health/aphasia

inability to form words
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a loss of ability to form words.
has_obo_namespace: symptoms
id: SYMP:0000217

Axiom
annotated source: inability to form words
annotated property: definition
annotated target: An aphasia that is characterized by a loss of ability to form words.
database_cross_reference: url:https://www.healthline.com/health/aphasia#causes
database_cross_reference: url:https://www.nidcd.nih.gov/health/aphasia

poor enunciation
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a loss of ability to properly enunciate words.
has_obo_namespace: symptoms
id: SYMP:0000218

Axiom
annotated source: poor enunciation
annotated property: definition
annotated target: An aphasia that is characterized by a loss of ability to properly enunciate words.
database_cross_reference: url:https://www.healthline.com/health/aphasia#causes
database_cross_reference: url:https://www.nidcd.nih.gov/health/aphasia

receptive aphasia
type: Class
subclass of: inability to comprehend speech
definition: An inability to comprehend speech that is characterized by an inability to understand spoken, written, or tactile speech symbols that results from damage (as by a brain lesion) to an area of the brain (as Wernicke's area) concerned with language.
has_exact_synonym: Wernicke's aphasia
has_exact_synonym: fluent aphasia
has_exact_synonym: inability to perceive pitch, rhythm, and emotional tone of speech
has_exact_synonym: sensory aphasia
has_obo_namespace: symptoms
id: SYMP:0000219

Axiom
annotated source: receptive aphasia
annotated property: definition
annotated target: An inability to comprehend speech that is characterized by an inability to understand spoken, written, or tactile speech symbols that results from damage (as by a brain lesion) to an area of the brain (as Wernicke's area) concerned with language.

areflexia
type: Class
subclass of: reflex symptom
has_exact_synonym: absence of neurological reflexes
has_obo_namespace: symptoms
id: SYMP:0000220

absence of knee jerk reflex
type: Class
subclass of: areflexia
has_obo_namespace: symptoms
id: SYMP:0000221

limb weakness
type: Class
subclass of: muscle weakness
has_exact_synonym: extremities weakness
has_obo_namespace: symptoms
id: SYMP:0000222

arm weakness
type: Class
subclass of: limb weakness
has_obo_namespace: symptoms
id: SYMP:0000223

leg weakness
type: Class
subclass of: limb weakness
has_obo_namespace: symptoms
id: SYMP:0000224

asthenia
type: Class
subclass of: general symptom
has_exact_synonym: loss of strength
has_obo_namespace: symptoms
id: SYMP:0000225
comment: doid/symp duplicate

atrial fibrillation
type: Class
subclass of: cardiac fibrillation
definition: A cardiac fibrillation consisting of a very rapid uncoordinated contractions of the atria of the heart resulting in a lack of synchronism between heartbeat and pulse beat.
has_exact_synonym: AF
has_exact_synonym: AFib
has_exact_synonym: a-fib
has_exact_synonym: auricular fibrillation
has_obo_namespace: symptoms
id: SYMP:0000226
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

Axiom
annotated source: atrial fibrillation
annotated property: definition
annotated target: A cardiac fibrillation consisting of a very rapid uncoordinated contractions of the atria of the heart resulting in a lack of synchronism between heartbeat and pulse beat.

blood vessel infection
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000227

hemorrhagic diarrhea
type: Class
subclass of: diarrhea
has_obo_namespace: symptoms
id: SYMP:0000228

bloody stool
type: Class
subclass of: feces and droppings symptom
has_exact_synonym: blood in stool
has_obo_namespace: symptoms
id: SYMP:0000229

body ache
type: Class
subclass of: pain
has_obo_namespace: symptoms
id: SYMP:0000230

bradycardia
type: Class
subclass of: arrhythmia
definition: Bradycardia is a cardiovascular system symptom consisting of a relatively slow heart action whether physiological or pathological.
has_obo_namespace: symptoms
id: SYMP:0000231

Axiom
annotated source: bradycardia
annotated property: definition
annotated target: Bradycardia is a cardiovascular system symptom consisting of a relatively slow heart action whether physiological or pathological.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradycardia

bronchiolitis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an inflammation of the bronchioles.
has_exact_synonym: bronchioles inflammation
has_obo_namespace: symptoms
id: SYMP:0000232
comment: doid/symp duplicate

Axiom
annotated source: bronchiolitis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an inflammation of the bronchioles.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bronchiolitis

inability to think clearly
type: Class
subclass of: alteration of consciousness
has_exact_synonym: clouded sensorium
has_exact_synonym: decreased sensorium
has_obo_namespace: symptoms
id: SYMP:0000233

cloudy cornea
type: Class
subclass of: cornea symptom
has_obo_namespace: symptoms
id: SYMP:0000234

colic
type: Class
subclass of: pain
definition: A pain that is characterized by the condition marked by recurrent episodes of prolonged and uncontrollable crying and irritability in an otherwise healthy infant that is of unknown cause and usually subsides after three to four months of age.
has_obo_namespace: symptoms
id: SYMP:0000235

Axiom
annotated source: colic
annotated property: definition
annotated target: A pain that is characterized by the condition marked by recurrent episodes of prolonged and uncontrollable crying and irritability in an otherwise healthy infant that is of unknown cause and usually subsides after three to four months of age.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=colic

colicky pain
type: Class
subclass of: pain
definition: A pain that is characterized by an attack of acute abdominal pain localized in a hollow organ or part (as the small intestine, ureter, or bile duct) and often caused by spasm, obstruction, or twisting.
has_obo_namespace: symptoms
id: SYMP:0000236

Axiom
annotated source: colicky pain
annotated property: definition
annotated target: A pain that is characterized by an attack of acute abdominal pain localized in a hollow organ or part (as the small intestine, ureter, or bile duct) and often caused by spasm, obstruction, or twisting.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=colic

congestion
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an excessive accumulation especially of blood or mucus.
has_exact_synonym: blocked nose
has_exact_synonym: nasal blockage
has_exact_synonym: nasal obstruction
has_exact_synonym: stuffed up nose
has_exact_synonym: stuffy nose
has_obo_namespace: symptoms
id: SYMP:0000237

Axiom
annotated source: congestion
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an excessive accumulation especially of blood or mucus.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=congestion

continuous profuse salivation
type: Class
subclass of: salivation
has_obo_namespace: symptoms
id: SYMP:0000238

cornea symptom
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000239

corneal opacity
type: Class
subclass of: cornea symptom
has_obo_namespace: symptoms
id: SYMP:0000240

corneal ulcers
type: Class
subclass of: cornea symptom
has_obo_namespace: symptoms
id: SYMP:0000241

cough with bloody sputum
type: Class
subclass of: cough
definition: A cough that is characterized by production and expectoration (bringing up) of sputum that is bright red or pink and frothy.
has_obo_namespace: symptoms
id: SYMP:0000242

Axiom
annotated source: cough with bloody sputum
annotated property: definition
annotated target: A cough that is characterized by production and expectoration (bringing up) of sputum that is bright red or pink and frothy.
database_cross_reference: url:https://www.webmd.com/lung/coughing-up-blood

cyclic fever
type: Class
subclass of: fever
definition: A fever that is characterized by occurring during periodic episodes.
has_alternative_id: SYMP:0000884
has_exact_synonym: recurrent fever
has_obo_namespace: symptoms
has_related_synonym: intermittent fever
id: SYMP:0000243

Axiom
annotated source: cyclic fever
annotated property: definition
annotated target: A fever that is characterized by occurring during periodic episodes.
database_cross_reference: url:http://en.wikipedia.org/wiki/Fever#Types
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/cyclic_fever_in_children.htm

alteration of appetite
type: Class
subclass of: nutrition, metabolism, and development symptom
has_obo_namespace: symptoms
id: SYMP:0000244

decreased appetite
type: Class
subclass of: alteration of appetite
definition: An alteration of appetite that is characterized by a reduced desire to eat.
has_exact_synonym: poor appetite
has_obo_namespace: symptoms
id: SYMP:0000245

Axiom
annotated source: decreased appetite
annotated property: definition
annotated target: An alteration of appetite that is characterized by a reduced desire to eat.
database_cross_reference: url:https://www.healthline.com/health/appetite-decreased

increased appetite
type: Class
subclass of: alteration of appetite
definition: An alteration of appetite that is characterized by an desire to eat, an excess desire for food.
has_obo_namespace: symptoms
id: SYMP:0000246

Axiom
annotated source: increased appetite
annotated property: definition
annotated target: An alteration of appetite that is characterized by an desire to eat, an excess desire for food.
database_cross_reference: url:https://medlineplus.gov/ency/article/003134.htm

proprioception symptom
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by one's body’s ability to sense movement, action, and location and results from sensory receptors in one's nervous system and body (muscles, joints, and tendons).
has_obo_namespace: symptoms
id: SYMP:0000247

Axiom
annotated source: proprioception symptom
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by one's body’s ability to sense movement, action, and location and results from sensory receptors in one's nervous system and body (muscles, joints, and tendons).
database_cross_reference: url:https://www.webmd.com/brain/what-is-proprioception

decreased conscious proprioception
type: Class
subclass of: proprioception symptom
definition: A proprioception symptom that is characterized by a decreased ability of an organism to consciously process the reception of stimuli produced within the organism.
has_obo_namespace: symptoms
id: SYMP:0000248

Axiom
annotated source: decreased conscious proprioception
annotated property: definition
annotated target: A proprioception symptom that is characterized by a decreased ability of an organism to consciously process the reception of stimuli produced within the organism.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=proprioception

reflex symptom
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000249

decreased flexor withdrawal reflex
type: Class
subclass of: reflex symptom
has_obo_namespace: symptoms
id: SYMP:0000250

dermal abscess
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a pus-filled pocket in the skin, similar to a pimple, but larger and deeper. The pocket is filled with bacteria, white blood cells, and dead skin and typcally result from the bacteria Staphylococcus aureus prentrating the skin through a cut or hair follicle.
has_exact_synonym: cutaneous abscess
has_exact_synonym: dermal abscesses
has_exact_synonym: skin abscess
has_exact_synonym: subcutaneous abscess
has_obo_namespace: symptoms
id: SYMP:0000251

Axiom
annotated source: dermal abscess
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a pus-filled pocket in the skin, similar to a pimple, but larger and deeper. The pocket is filled with bacteria, white blood cells, and dead skin and typcally result from the bacteria Staphylococcus aureus prentrating the skin through a cut or hair follicle.
database_cross_reference: url:https://jamanetwork.com/journals/jama/fullarticle/2677448

diffuse rash
type: Class
subclass of: rash
definition: A rash characterized by large patches of red skin, without overlying changes in the epidermis.
has_exact_synonym: diffuse erythema
has_obo_namespace: symptoms
id: SYMP:0000252

Axiom
annotated source: diffuse rash
annotated property: definition
annotated target: A rash characterized by large patches of red skin, without overlying changes in the epidermis.
database_cross_reference: url:https://www.drugwatch.com/health/rash-and-skin-disorders/erythema/
database_cross_reference: url:https://www.sciencedirect.com/topics/medicine-and-dentistry/erythema

anisocoria
type: Class
subclass of: eye symptom
has_exact_synonym: enlargement of one pupil
has_exact_synonym: pupils of different size
has_obo_namespace: symptoms
id: SYMP:0000253

dilated pupil
type: Class
subclass of: pupil symptom
has_obo_namespace: symptoms
id: SYMP:0000254

diminished gastro-intestinal motility
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000255

diminished gag reflex
type: Class
subclass of: reflex symptom
has_obo_namespace: symptoms
id: SYMP:0000256

absent gag reflex
type: Class
subclass of: areflexia
has_obo_namespace: symptoms
id: SYMP:0000257

double vision
type: Class
subclass of: vision symptom
has_exact_synonym: diplopia
has_obo_namespace: symptoms
id: SYMP:0000258

dry hacking cough
type: Class
subclass of: dry cough
definition: A dry cough that is characterized by a rough and loud sound.
has_obo_namespace: symptoms
id: SYMP:0000259

Axiom
annotated source: dry hacking cough
annotated property: definition
annotated target: A dry cough that is characterized by a rough and loud sound.
database_cross_reference: url:https://en.wiktionary.org/wiki/hacking_cough

dry mouth
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000260

dry mucous membrane
type: Class
subclass of: skin and integumentary tissue symptom
has_exact_synonym: dry mucous membranes
has_obo_namespace: symptoms
id: SYMP:0000261

endocarditis
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000262
comment: doid/symp duplicate

epididymitis
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by an inflammation of the epididymis.
has_exact_synonym: inflammation of the epididymis
has_obo_namespace: symptoms
id: SYMP:0000263
comment: doid/symp duplicate

Axiom
annotated source: epididymitis
annotated property: definition
annotated target: A reproductive system symptom that is characterized by an inflammation of the epididymis.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=epididymitis

epididymorchitis
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by inflammation of the epididymis and/or testicle (testis).
has_exact_synonym: epididymo-orchitis
has_obo_namespace: symptoms
id: SYMP:0000264

Axiom
annotated source: epididymorchitis
annotated property: definition
annotated target: A reproductive system symptom that is characterized by inflammation of the epididymis and/or testicle (testis).
database_cross_reference: url:https://patient.info/mens-health/scrotal-lumps-pain-and-swelling/epididymo-orchitis

obsolete absence seizure
type: Class
has_exact_synonym: petit mal seizure
has_obo_namespace: symptoms
id: SYMP:0000265
comment: reviewed 10/2022 & determined to be a disease
deprecated: true

focal seizure
type: Class
subclass of: seizure
has_exact_synonym: partial seizure
has_obo_namespace: symptoms
id: SYMP:0000266

generalized seizure
type: Class
subclass of: seizure
has_obo_namespace: symptoms
id: SYMP:0000267

tonic-clonic seizure
type: Class
subclass of: generalized seizure
has_exact_synonym: grand mal seizure
has_obo_namespace: symptoms
id: SYMP:0000268

epileptic seizure
type: Class
subclass of: seizure
has_obo_namespace: symptoms
id: SYMP:0000269

simple partial seizure
type: Class
subclass of: focal seizure
has_obo_namespace: symptoms
id: SYMP:0000270

complex partial seizure
type: Class
subclass of: focal seizure
has_obo_namespace: symptoms
id: SYMP:0000271

myoclonic seizure
type: Class
subclass of: generalized seizure
has_obo_namespace: symptoms
id: SYMP:0000272

clonic seizure
type: Class
subclass of: generalized seizure
has_obo_namespace: symptoms
id: SYMP:0000273

tonic seizure
type: Class
subclass of: generalized seizure
has_obo_namespace: symptoms
id: SYMP:0000274

atonic seizure
type: Class
subclass of: generalized seizure
has_obo_namespace: symptoms
id: SYMP:0000275

obsolete excess pericardial fluid
type: Class
has_obo_namespace: symptoms
id: SYMP:0000276
deprecated: true

excess salivation
type: Class
subclass of: salivation
has_exact_synonym: profuse salivation
has_obo_namespace: symptoms
id: SYMP:0000277

extensive ulcer
type: Class
subclass of: skin ulcer
has_obo_namespace: symptoms
id: SYMP:0000278

extreme exhaustion
type: Class
subclass of: exhaustion
definition: An exhaustion that is characterized by exceeding the ordinary, usual, or expected.
has_obo_namespace: symptoms
id: SYMP:0000279

Axiom
annotated source: extreme exhaustion
annotated property: definition
annotated target: An exhaustion that is characterized by exceeding the ordinary, usual, or expected.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/extreme

extreme fatigue
type: Class
subclass of: fatigue
definition: A fatigue that is characterized by exceeding the ordinary, usual, or expected.
has_obo_namespace: symptoms
id: SYMP:0000280

Axiom
annotated source: extreme fatigue
annotated property: definition
annotated target: A fatigue that is characterized by exceeding the ordinary, usual, or expected.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/extreme

eye discharge
type: Class
subclass of: eye symptom
has_exact_synonym: ocular discharge
has_obo_namespace: symptoms
id: SYMP:0000281

fixed dilated pupils
type: Class
subclass of: dilated pupil
has_obo_namespace: symptoms
id: SYMP:0000282

facial paralysis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000283
comment: doid/symp duplicate

fixed pupil
type: Class
subclass of: eye symptom
has_exact_synonym: fixed pupils
has_obo_namespace: symptoms
id: SYMP:0000284

flaccid paralysis
type: Class
subclass of: paralysis
definition: A paralysis that is charicterized by a lack of muscle tone in the affected muscles and in which tendon reflexes are decreased or absent.
has_obo_namespace: symptoms
id: SYMP:0000285

Axiom
annotated source: flaccid paralysis
annotated property: definition
annotated target: A paralysis that is charicterized by a lack of muscle tone in the affected muscles and in which tendon reflexes are decreased or absent.

obsolete floppy head
type: Class
has_obo_namespace: symptoms
id: SYMP:0000286
comment: reviewed 10/2022 & determined to be a disease
deprecated: true

arrhythmia
type: Class
subclass of: cardiovascular system symptom
definition: Arrhythmia is a cardiovascular system symptom consisting of an alteration in rhythm of the heartbeat either in time or force.
has_alternative_id: SYMP:0000288
has_alternative_id: SYMP:0000667
has_alternative_id: SYMP:0000668
has_exact_synonym: abnormal heart beat
has_exact_synonym: abnormal heart rhythm
has_exact_synonym: dysrhythmia
has_exact_synonym: heart rhythm symptom
has_exact_synonym: irregular heartbeat
has_obo_namespace: symptoms
has_related_synonym: fluctuation of heart rate
id: SYMP:0000287

Axiom
annotated source: arrhythmia
annotated property: definition
annotated target: Arrhythmia is a cardiovascular system symptom consisting of an alteration in rhythm of the heartbeat either in time or force.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=arrhythmia

eczema
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an inflammatory condition of the skin with redness, itching, and oozing vesicular lesions, which become scaly, crusted, or hardened.
has_obo_namespace: symptoms
id: SYMP:0000289

Axiom
annotated source: eczema
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an inflammatory condition of the skin with redness, itching, and oozing vesicular lesions, which become scaly, crusted, or hardened.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=eczema

belching
type: Class
subclass of: digestive system symptom
definition: Belching is a digestive system symptom involving the sudden expulsion of gas from the stomach through the mouth.
has_exact_synonym: eructation
has_obo_namespace: symptoms
id: SYMP:0000290

Axiom
annotated source: belching
annotated property: definition
annotated target: Belching is a digestive system symptom involving the sudden expulsion of gas from the stomach through the mouth.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=belching

gas pain
type: Class
subclass of: pain
has_obo_namespace: symptoms
id: SYMP:0000291

heart failure
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000292

hemiparesis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000293

hemolysis
type: Class
subclass of: hemic system symptom
has_exact_synonym: haemolysis
has_obo_namespace: symptoms
id: SYMP:0000294

hepatic abscess
type: Class
subclass of: liver symptom
has_exact_synonym: hepatic abscesses
has_obo_namespace: symptoms
id: SYMP:0000295

hepatic dysfunction
type: Class
subclass of: liver symptom
has_obo_namespace: symptoms
id: SYMP:0000296

hilar lymphadenitis
type: Class
subclass of: lymphadenitis
has_obo_namespace: symptoms
id: SYMP:0000297

hoarse voice
type: Class
subclass of: voice disturbance
has_obo_namespace: symptoms
id: SYMP:0000298

hyperemia
type: Class
subclass of: hemic system symptom
definition: Hyperemia is a hemic system symptom consisting of an excess of blood in a body part as from an increased flow of blood due to vasodilation.
has_exact_synonym: hyperaemia
has_exact_synonym: hyperemic
has_obo_namespace: symptoms
id: SYMP:0000299

Axiom
annotated source: hyperemia
annotated property: definition
annotated target: Hyperemia is a hemic system symptom consisting of an excess of blood in a body part as from an increased flow of blood due to vasodilation.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperemia

hyperesthesia
type: Class
subclass of: sensation perception
definition: A sensation perception that is characterized by an increased sensitivity to stimulation.
has_exact_synonym: hyperaesthesia
has_obo_namespace: symptoms
id: SYMP:0000300

Axiom
annotated source: hyperesthesia
annotated property: definition
annotated target: A sensation perception that is characterized by an increased sensitivity to stimulation.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

hypopyon
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000301
comment: doid/symp duplicate

hypothermia
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a subnormal temperature of the body, as defined by a temperature under 36.6 degrees Celcius (97.8 degrees Fahrenheit).
has_obo_namespace: symptoms
id: SYMP:0000302

Axiom
annotated source: hypothermia
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a subnormal temperature of the body, as defined by a temperature under 36.6 degrees Celcius (97.8 degrees Fahrenheit).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypothermia

hypoxemia
type: Class
subclass of: hemic system symptom
has_exact_synonym: hypoxaemia
has_obo_namespace: symptoms
id: SYMP:0000303

impaired coordination
type: Class
subclass of: coordination symptom
definition: A coordination symptom that is characterized by weakened or imperfect body complicated movement, which may be caused by disease, injury, or toxins.
has_obo_namespace: symptoms
id: SYMP:0000304

Axiom
annotated source: impaired coordination
annotated property: definition
annotated target: A coordination symptom that is characterized by weakened or imperfect body complicated movement, which may be caused by disease, injury, or toxins.
database_cross_reference: url:https://www.healthline.com/health/movement-uncoordinated
database_cross_reference: url:https://www.merckmanuals.com/home/brain,-spinal-cord,-and-nerve-disorders/movement-disorders/coordination-disorders

impaired gag reflex
type: Class
subclass of: reflex symptom
has_obo_namespace: symptoms
id: SYMP:0000305

inability to feed
type: Class
subclass of: feeding difficulties and mismanagement
definition: A feeding difficulties and mismanagement that is characterized by a lack of feeding capacity.
has_obo_namespace: symptoms
id: SYMP:0000306

Axiom
annotated source: inability to feed
annotated property: definition
annotated target: A feeding difficulties and mismanagement that is characterized by a lack of feeding capacity.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851259/

inibility to stand
type: Class
subclass of: motor weakness
has_obo_namespace: symptoms
id: SYMP:0000307

inability to swallow
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000308

loss of appetite
type: Class
subclass of: alteration of appetite
definition: An alteration of appetite that is characterized by a loss of desire to eat, i.e. no desire to eat.
has_exact_synonym: inappetence
has_exact_synonym: lack of appetite
has_obo_namespace: symptoms
id: SYMP:0000309

Axiom
annotated source: loss of appetite
annotated property: definition
annotated target: An alteration of appetite that is characterized by a loss of desire to eat, i.e. no desire to eat.
database_cross_reference: url:https://www.merckmanuals.com/home/digestive-disorders/symptoms-of-digestive-disorders/loss-of-appetite

inflamed eyes
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000310

intestinal hypermotility
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000311

joint symptom
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000312

joint inflammation
type: Class
subclass of: joint symptom
has_obo_namespace: symptoms
id: SYMP:0000313

keratitis
type: Class
subclass of: cornea symptom
has_exact_synonym: corneitis
has_exact_synonym: inflammation of the cornea of the eye
has_obo_namespace: symptoms
id: SYMP:0000314
comment: doid/symp duplicate

lateroventral deviation of the head
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000315

leg cramp
type: Class
subclass of: muscle cramp
has_obo_namespace: symptoms
id: SYMP:0000316

obsolete leukopenia
type: Class
has_exact_synonym: low white blood cell count
has_obo_namespace: symptoms
id: SYMP:0000317
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

loss of balance
type: Class
subclass of: balance symptom
definition: A balance symptom that is characterized by an inability to stay upright and move confidently. Loss of balance may be due to problems in the inner ear, the brain, or the heart. Aging, infections, head injury, certain medicines, and problems with blood circulation may also cause balance problems.
has_obo_namespace: symptoms
id: SYMP:0000318

Axiom
annotated source: loss of balance
annotated property: definition
annotated target: A balance symptom that is characterized by an inability to stay upright and move confidently. Loss of balance may be due to problems in the inner ear, the brain, or the heart. Aging, infections, head injury, certain medicines, and problems with blood circulation may also cause balance problems.
database_cross_reference: url:https://medlineplus.gov/balanceproblems.html
database_cross_reference: url:https://www.nidcd.nih.gov/health/balance-disorders

loss of tendon reflex
type: Class
subclass of: reflex symptom
has_obo_namespace: symptoms
id: SYMP:0000319

vision symptom
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000320

loss of vision
type: Class
subclass of: vision symptom
has_obo_namespace: symptoms
id: SYMP:0000321

low birth weight
type: Class
subclass of: weight symptom
definition: A weight symptom that is characterized by an infant weighing 5.5 pounds (2500 grams) or less at birth. Low birth weight may occur with premature birth, or due to smoking cigarettes, secondhand tobacco smoke exposure, drinking alcohol, and taking certain drugs during pregnancy.
has_obo_namespace: symptoms
id: SYMP:0000322

Axiom
annotated source: low birth weight
annotated property: definition
annotated target: A weight symptom that is characterized by an infant weighing 5.5 pounds (2500 grams) or less at birth. Low birth weight may occur with premature birth, or due to smoking cigarettes, secondhand tobacco smoke exposure, drinking alcohol, and taking certain drugs during pregnancy.
database_cross_reference: url:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/low-birth-weight

melena
type: Class
subclass of: feces and droppings symptom
definition: A feces and droppings symptom that is characterized by the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum.
has_exact_synonym: melaena
has_obo_namespace: symptoms
id: SYMP:0000323

Axiom
annotated source: melena
annotated property: definition
annotated target: A feces and droppings symptom that is characterized by the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum.
database_cross_reference: url:http://www.merriam-webster.com/medlineplus/melena

bronchitis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an acute or chronic inflammation of the bronchial tubes.
has_obo_namespace: symptoms
id: SYMP:0000324
comment: doid/symp duplicate

Axiom
annotated source: bronchitis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an acute or chronic inflammation of the bronchial tubes.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bronchitis

mild bronchitis
type: Class
subclass of: bronchitis
has_obo_namespace: symptoms
id: SYMP:0000325

mild hypotension
type: Class
subclass of: hypotension
has_obo_namespace: symptoms
id: SYMP:0000326

tetanic convulsion
type: Class
subclass of: convulsion
definition: A convulsion that is characterized by a tonic spasm (prolonged contraction of the muscles), without loss of consciousness and often associated with hypocalcemia.
has_exact_synonym: tetanic convulsions
has_obo_namespace: symptoms
id: SYMP:0000327

Axiom
annotated source: tetanic convulsion
annotated property: definition
annotated target: A convulsion that is characterized by a tonic spasm (prolonged contraction of the muscles), without loss of consciousness and often associated with hypocalcemia.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/tetanic

mild tetanic convulsion
type: Class
subclass of: tetanic convulsion
definition: A tetanic convulsion that is not intense (not severe).
has_obo_namespace: symptoms
id: SYMP:0000328

Axiom
annotated source: mild tetanic convulsion
annotated property: definition
annotated target: A tetanic convulsion that is not intense (not severe).
database_cross_reference: url:https://www.macmillandictionary.com/us/dictionary/american/mild_1

motor weakness
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000329

mouth sore
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000330

muscle ache
type: Class
subclass of: muscle pain
definition: A pain that is characterized by a continuous or prolonged dull pain.
has_obo_namespace: symptoms
id: SYMP:0000331

Axiom
annotated source: muscle ache
annotated property: definition
annotated target: A pain that is characterized by a continuous or prolonged dull pain.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/ache

muscle soreness
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000332

muscle tenderness
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000333

muscle necrosis
type: Class
subclass of: muscle symptom
subclass of: soft tissue necrosis
has_obo_namespace: symptoms
id: SYMP:0000334

neck weakness
type: Class
subclass of: neck symptom
has_obo_namespace: symptoms
id: SYMP:0000335

neurological dysfunction
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000336

night sweats
type: Class
subclass of: sleep disturbance
has_exact_synonym: sleep hyperhidrosis
has_obo_namespace: symptoms
id: SYMP:0000337

nystagmus
type: Class
subclass of: eye symptom
has_exact_synonym: rapid involuntary rhythmic eye movement
has_obo_namespace: symptoms
id: SYMP:0000338

occasional diplopia
type: Class
subclass of: double vision
has_obo_namespace: symptoms
id: SYMP:0000339

limb edema
type: Class
subclass of: edema
definition: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the limbs.
has_exact_synonym: limb oedema
has_exact_synonym: oedema of the limbs
has_obo_namespace: symptoms
id: SYMP:0000340

Axiom
annotated source: limb edema
annotated property: definition
annotated target: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the limbs.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536506/

obsolete ophthalmoplegia
type: Class
has_exact_synonym: extraocular muscle paralysis
has_exact_synonym: eye movement paralysis
has_obo_namespace: symptoms
id: SYMP:0000341
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

slurred speech
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000342

painful lymph glands
type: Class
subclass of: pain
definition: A pain that is characterized by a pain situated, or occurring, in the lymph gland (lymph node). Pain is often associated with swelling of the gland, which is a sign that one's body is fighting an infection.
has_exact_synonym: painful lymph nodes
has_obo_namespace: symptoms
id: SYMP:0000343

Axiom
annotated source: painful lymph glands
annotated property: definition
annotated target: A pain that is characterized by a pain situated, or occurring, in the lymph gland (lymph node). Pain is often associated with swelling of the gland, which is a sign that one's body is fighting an infection.
database_cross_reference: url:https://en.wikipedia.org/wiki/Lymph_node
database_cross_reference: url:https://www.nhs.uk/conditions/swollen-glands/
database_cross_reference: url:https://www.webmd.com/a-to-z-guides/swollen-glands

palpebral edema
type: Class
subclass of: edema
definition: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the eyelids.
has_exact_synonym: edema of the eyelid
has_obo_namespace: symptoms
id: SYMP:0000344

Axiom
annotated source: palpebral edema
annotated property: definition
annotated target: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the eyelids.
database_cross_reference: url:https://scopeheal.com/palpebral-edema/

panting respiration
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by short, shallow, and rapid breathing.
has_obo_namespace: symptoms
id: SYMP:0000345

Axiom
annotated source: panting respiration
annotated property: definition
annotated target: A respiratory abnormality that is characterized by short, shallow, and rapid breathing.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/panting

papule
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a small solid usually conical elevation of the skin caused by inflammation, accumulated secretion, or hypertrophy of tissue elements.
has_obo_namespace: symptoms
id: SYMP:0000346

Axiom
annotated source: papule
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a small solid usually conical elevation of the skin caused by inflammation, accumulated secretion, or hypertrophy of tissue elements.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=papule

lip paralysis
type: Class
subclass of: paralysis
has_exact_synonym: paralysed lips
has_obo_namespace: symptoms
id: SYMP:0000347

throat muscle paralysis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000348

paraplegia
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000349
comment: doid/symp duplicate

parotid abscess
type: Class
subclass of: salivary gland symptom
has_obo_namespace: symptoms
id: SYMP:0000350

obsolete partial paralysis of the limbs
type: Class
has_obo_namespace: symptoms
id: SYMP:0000351
deprecated: true

peripheral muscle weakness
type: Class
subclass of: muscle weakness
has_obo_namespace: symptoms
id: SYMP:0000352

phlegm
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a viscid mucus secreted in abnormal quantity in the respiratory passages.
has_obo_namespace: symptoms
id: SYMP:0000353

Axiom
annotated source: phlegm
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a viscid mucus secreted in abnormal quantity in the respiratory passages.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=phlegm

pneumonitis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an inflammation of lung tissue. Pneumonia is one type of pneumonitis caused by an infection. Many other factors can cause pneumonitis, including breathing in animal dander, inhaling small food particles 'down the wrong pipe' and receiving radiation therapy to your chest.
has_exact_synonym: inflammation of lung tissue
has_obo_namespace: symptoms
id: SYMP:0000354

Axiom
annotated source: pneumonitis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an inflammation of lung tissue. Pneumonia is one type of pneumonitis caused by an infection. Many other factors can cause pneumonitis, including breathing in animal dander, inhaling small food particles 'down the wrong pipe' and receiving radiation therapy to your chest.
database_cross_reference: url:http://en.wikipedia.org/wiki/Pneumonitis

poor feeding
type: Class
subclass of: feeding difficulties and mismanagement
definition: A feeding difficulties and mismanagement that is characterized by an infant with little interest in feeding and it can also refer to an infant who is not feeding enough to receive the necessary nutrition required for adequate growth.
has_obo_namespace: symptoms
id: SYMP:0000355

Axiom
annotated source: poor feeding
annotated property: definition
annotated target: A feeding difficulties and mismanagement that is characterized by an infant with little interest in feeding and it can also refer to an infant who is not feeding enough to receive the necessary nutrition required for adequate growth.
database_cross_reference: url:https://www.healthline.com/health/poor-feeding-in-infants

phlebitis
type: Class
subclass of: cardiovascular system symptom
has_exact_synonym: inflammation of a vein
has_obo_namespace: symptoms
id: SYMP:0000356
comment: doid/symp duplicate

postphlebitic ulcer
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000357

premature labor
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by labor occurring before 37 full weeks of pregnancy.
has_obo_namespace: symptoms
id: SYMP:0000358

Axiom
annotated source: premature labor
annotated property: definition
annotated target: A reproductive system symptom that is characterized by labor occurring before 37 full weeks of pregnancy.
database_cross_reference: url:http://www.ehealthmd.com/library/amniocentesis/AMO_glossary.html

profound weakness
type: Class
subclass of: weakness
has_obo_namespace: symptoms
id: SYMP:0000359

emaciation
type: Class
subclass of: wasting
definition: A wasting that is characterized by the state of being extremely thin as a result of an absence of body fat and very week as a result of muscle wasting; usually because of illness or extreme hunger.
has_obo_namespace: symptoms
id: SYMP:0000360

Axiom
annotated source: emaciation
annotated property: definition
annotated target: A wasting that is characterized by the state of being extremely thin as a result of an absence of body fat and very week as a result of muscle wasting; usually because of illness or extreme hunger.
database_cross_reference: url:https://dictionary.cambridge.org/us/dictionary/english/emaciation
database_cross_reference: url:https://en.wikipedia.org/wiki/Emaciation

progressive emaciation
type: Class
subclass of: emaciation
definition: An emaciation that is characterized by an increase in scope or severity with time.
has_obo_namespace: symptoms
id: SYMP:0000361

Axiom
annotated source: progressive emaciation
annotated property: definition
annotated target: An emaciation that is characterized by an increase in scope or severity with time.
database_cross_reference: url:https://www.rxlist.com/progressive/definition.htm

progressive prostration
type: Class
subclass of: prostration
has_obo_namespace: symptoms
id: SYMP:0000362

progressive weakness
type: Class
subclass of: weakness
has_obo_namespace: symptoms
id: SYMP:0000363

prostate symptom
type: Class
subclass of: reproductive system symptom
has_obo_namespace: symptoms
id: SYMP:0000364

prostatic abscess
type: Class
subclass of: prostate symptom
definition: A prostate symptom that is characterized by a localized collection of purulent fluid within the prostate, often forming as a complication of acute bacterial prostatitis.
has_obo_namespace: symptoms
id: SYMP:0000365

Axiom
annotated source: prostatic abscess
annotated property: definition
annotated target: A prostate symptom that is characterized by a localized collection of purulent fluid within the prostate, often forming as a complication of acute bacterial prostatitis.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK551663/

prostatic infection
type: Class
subclass of: prostate symptom
definition: A prostate symptom that is characterized by inflammation of the prostate and surrounding area.
has_obo_namespace: symptoms
id: SYMP:0000366

Axiom
annotated source: prostatic infection
annotated property: definition
annotated target: A prostate symptom that is characterized by inflammation of the prostate and surrounding area.
database_cross_reference: url:https://www.healthline.com/health/prostate-infection#

proteinuria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom characterized by the presence of excess protein in the urine.
has_obo_namespace: symptoms
id: SYMP:0000367
comment: doid/symp duplicate

Axiom
annotated source: proteinuria
annotated property: definition
annotated target: A urinary system symptom characterized by the presence of excess protein in the urine.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=proteinuria

proximal paralysis of arm and leg
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000368

ptosis
type: Class
subclass of: general symptom
definition: Ptosis is a general symptom characterized by a sagging or prolapse of an organ or part.
has_exact_synonym: droopiness
has_obo_namespace: symptoms
id: SYMP:0000369
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

Axiom
annotated source: ptosis
annotated property: definition
annotated target: Ptosis is a general symptom characterized by a sagging or prolapse of an organ or part.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ptosis

renal abscess
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by a pocket (a walled-off cavity) of pus that develops in the kidney tissue. It results from the migration of bacteria from another infection site on the body to the kidneys.
has_exact_synonym: kidney abscess
has_exact_synonym: perirenal abscess
has_obo_namespace: symptoms
id: SYMP:0000370

Axiom
annotated source: renal abscess
annotated property: definition
annotated target: A urinary system symptom that is characterized by a pocket (a walled-off cavity) of pus that develops in the kidney tissue. It results from the migration of bacteria from another infection site on the body to the kidneys.
database_cross_reference: url:https://www.uptodate.com/contents/renal-and-perinephric-abscess

respiratory paralysis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000371

rhinorrhea
type: Class
subclass of: nose symptom
definition: A nose symptom that is characterized by an excessive secretion of mucous through the nose.
has_exact_synonym: runny nose
has_obo_namespace: symptoms
id: SYMP:0000372

Axiom
annotated source: rhinorrhea
annotated property: definition
annotated target: A nose symptom that is characterized by an excessive secretion of mucous through the nose.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=Rhinorrhea

salivation
type: Class
subclass of: salivary gland symptom
has_obo_namespace: symptoms
id: SYMP:0000373

scrotal abscess
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by an abscess that is either superficial or intrascrotal. Superficial scrotal abscess may occur from an infected hair follicle, infection of a scrotal laceration, or minor scrotal surgery. Intrascrotal abscess most commonly arises from bacterial epididymitis, but may also be related to tuberculous infection of the epididymis, a testicular abscess that ruptures through the tunica albuginea, or drainage of appendicitis into scrotum through a patent processus vaginalis or as a result of extravasation of infected urine from the urethra in patients with a urethral stricture and neurogenic bladder using an external collection device.
has_obo_namespace: symptoms
id: SYMP:0000374

Axiom
annotated source: scrotal abscess
annotated property: definition
annotated target: A reproductive system symptom that is characterized by an abscess that is either superficial or intrascrotal. Superficial scrotal abscess may occur from an infected hair follicle, infection of a scrotal laceration, or minor scrotal surgery. Intrascrotal abscess most commonly arises from bacterial epididymitis, but may also be related to tuberculous infection of the epididymis, a testicular abscess that ruptures through the tunica albuginea, or drainage of appendicitis into scrotum through a patent processus vaginalis or as a result of extravasation of infected urine from the urethra in patients with a urethral stricture and neurogenic bladder using an external collection device.
database_cross_reference: url:https://emedicine.medscape.com/article/1949750-overview

severe abdominal cramp
type: Class
subclass of: abdominal cramp
has_obo_namespace: symptoms
id: SYMP:0000375

severe diarrhea
type: Class
subclass of: diarrhea
has_obo_namespace: symptoms
id: SYMP:0000376

obsolete mastitis
type: Class
definition: A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection.
term replaced by: mammary gland inflammation
has_exact_synonym: inflammation of mammary breast
has_exact_synonym: mammitis
has_obo_namespace: symptoms
id: SYMP:0000377
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete mastitis
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=mastitis

obsolete severe mastitis
type: Class
definition: A mastitis that is characterized by an increased intensity or severity of the condition.
term replaced by: severe mammary gland inflammation
has_obo_namespace: symptoms
id: SYMP:0000378
comment: reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete severe mastitis
annotated property: definition
annotated target: A mastitis that is characterized by an increased intensity or severity of the condition.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/severe

severe myalgia
type: Class
subclass of: muscle pain
definition: A muscle pain that is characterized by being severe in nature. Myalgia may be acute in nature, stemming from overuse of a muscle group or viral infection. It may also be chronic and caused by metabolic myopathy, some nutritional deficiencies, and chronic fatigue syndrome.
has_obo_namespace: symptoms
id: SYMP:0000379

Axiom
annotated source: severe myalgia
annotated property: definition
annotated target: A muscle pain that is characterized by being severe in nature. Myalgia may be acute in nature, stemming from overuse of a muscle group or viral infection. It may also be chronic and caused by metabolic myopathy, some nutritional deficiencies, and chronic fatigue syndrome.
database_cross_reference: url:https://en.wikipedia.org/wiki/Myalgia

obsolete severe pneumonia
type: Class
term replaced by: severe bronchiole inflammation
has_obo_namespace: symptoms
id: SYMP:0000380
comment: reviewed 10/2022 & determined to be a disease
deprecated: true

spleen abscess
type: Class
subclass of: spleen symptom
has_obo_namespace: symptoms
id: SYMP:0000381

staggering gait
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000382

stiff neck
type: Class
subclass of: neck symptom
has_obo_namespace: symptoms
id: SYMP:0000383

neck symptom
type: Class
subclass of: head and neck symptom
has_exact_synonym: cervicalgia
has_obo_namespace: symptoms
id: SYMP:0000384

throat symptom
type: Class
subclass of: head and neck symptom
has_obo_namespace: symptoms
id: SYMP:0000385

mouth symptom
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000386

head symptom
type: Class
subclass of: head and neck symptom
has_obo_namespace: symptoms
id: SYMP:0000387

nose symptom
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000388

stupor
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a lack of critical mental function and a level of consciousness, in which an affected person is almost entirely unresponsive and responds only to intense stimuli such as pain.
has_obo_namespace: symptoms
id: SYMP:0000389

Axiom
annotated source: stupor
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a lack of critical mental function and a level of consciousness, in which an affected person is almost entirely unresponsive and responds only to intense stimuli such as pain.
database_cross_reference: url:https://en.wikipedia.org/wiki/Stupor

thyroid symptom
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000390

thyroid abscesses
type: Class
subclass of: thyroid symptom
has_obo_namespace: symptoms
id: SYMP:0000391

ear symptom
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000392

tinnitus
type: Class
subclass of: ear symptom
has_exact_synonym: sensation of noise
has_obo_namespace: symptoms
id: SYMP:0000393

muscle twitching
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000394

facial muscle twitching
type: Class
subclass of: muscle twitching
has_obo_namespace: symptoms
id: SYMP:0000395

mydriasis
type: Class
subclass of: dilated pupil
has_exact_synonym: excessive pupil dilation
has_exact_synonym: prolonged pupil dilation
has_obo_namespace: symptoms
id: SYMP:0000396

unreactive mydriasis
type: Class
subclass of: mydriasis
has_obo_namespace: symptoms
id: SYMP:0000397

vaginal discharge
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by fluid made by glands inside the vagina and cervix carrying away dead cells and bacteria. While it is normal for odor and color to vary, vaginal itching or burning may be indicative of an infection.
has_obo_namespace: symptoms
id: SYMP:0000398
comment: doid/symp duplicate

Axiom
annotated source: vaginal discharge
annotated property: definition
annotated target: A reproductive system symptom that is characterized by fluid made by glands inside the vagina and cervix carrying away dead cells and bacteria. While it is normal for odor and color to vary, vaginal itching or burning may be indicative of an infection.
database_cross_reference: url:https://www.merckmanuals.com/professional/gynecology-and-obstetrics/symptoms-of-gynecologic-disorders/vaginal-bleeding
database_cross_reference: url:https://www.webmd.com/women/guide/vaginal-discharge-whats-abnormal

vertigo
type: Class
subclass of: dizziness
definition: A dizziness that is characterized by a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is stationary with respect to the surroundings.
has_obo_namespace: symptoms
id: SYMP:0000399

Axiom
annotated source: vertigo
annotated property: definition
annotated target: A dizziness that is characterized by a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is stationary with respect to the surroundings.
database_cross_reference: url:http://en.wikipedia.org/wiki/Vertigo_%28medical%29

weak cry
type: Class
subclass of: infant symptom
has_obo_namespace: symptoms
id: SYMP:0000400

wobble
type: Class
subclass of: abnormality of gait
has_obo_namespace: symptoms
id: SYMP:0000401

cachexia
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a general physical wasting and malnutrition usually associated with chronic disease.
has_exact_synonym: general physical wasting and malnutrition
has_obo_namespace: symptoms
id: SYMP:0000402

Axiom
annotated source: cachexia
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a general physical wasting and malnutrition usually associated with chronic disease.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cachexia

weight gain
type: Class
subclass of: weight symptom
definition: A weight symptom that is characterized by an increase in body weight. This can involve an increase in muscle mass, fat deposits, excess fluids such as water or other factors.
has_alternative_id: SYMP:0020015
has_exact_synonym: gain of weight
has_obo_namespace: symptoms
id: SYMP:0000403

Axiom
annotated source: weight gain
annotated property: definition
annotated target: A weight symptom that is characterized by an increase in body weight. This can involve an increase in muscle mass, fat deposits, excess fluids such as water or other factors.
database_cross_reference: url:https://en.wikipedia.org/wiki/Weight_gain#

dyspareunia
type: Class
subclass of: pain
has_exact_synonym: difficult sexual intercourse
has_exact_synonym: painful sexual intercourse
has_obo_namespace: symptoms
id: SYMP:0000404

vaginismus
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by a painful spasmodic contraction of the vagina.
has_exact_synonym: painful spasmodic vagina contractions
has_obo_namespace: symptoms
id: SYMP:0000405

Axiom
annotated source: vaginismus
annotated property: definition
annotated target: A reproductive system symptom that is characterized by a painful spasmodic contraction of the vagina.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=vaginismus

bruise
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an injury transmitted through unbroken skin to underlying tissue causing rupture of small blood vessels and escape of blood into the tissue with resulting discoloration.
has_exact_synonym: bruises
has_exact_synonym: bruising
has_exact_synonym: contusion
has_exact_synonym: ecchymosis
has_obo_namespace: symptoms
id: SYMP:0000406

Axiom
annotated source: bruise
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an injury transmitted through unbroken skin to underlying tissue causing rupture of small blood vessels and escape of blood into the tissue with resulting discoloration.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bruise

syncope
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain.
has_alternative_id: SYMP:0000445
has_exact_synonym: faint
has_exact_synonym: fainting
has_exact_synonym: loss of consciousness due to insuffiecient blood flow to the brain
has_obo_namespace: symptoms
id: SYMP:0000407

Axiom
annotated source: syncope
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain.
database_cross_reference: url:https://en.wikipedia.org/wiki/Syncope_(medicine)
database_cross_reference: url:https://www.merriam-webster.com/dictionary/fainting
database_cross_reference: url:https://www.merriam-webster.com/dictionary/syncope

cataplexy
type: Class
subclass of: muscle symptom
definition: Cataplexy is a muscle symptom characterized by a sudden loss of muscle control with retention of clear consciousness that follows a strong emotional stimulus (as elation, surprise, or anger) and is a characteristic symptom of narcolepsy.
has_obo_namespace: symptoms
id: SYMP:0000408

Axiom
annotated source: cataplexy
annotated property: definition
annotated target: Cataplexy is a muscle symptom characterized by a sudden loss of muscle control with retention of clear consciousness that follows a strong emotional stimulus (as elation, surprise, or anger) and is a characteristic symptom of narcolepsy.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cataplexy

hyperthermia
type: Class
subclass of: high fever
definition: A high fever that is characterized by an exceptionally high fever especially when induced artificially for therapeutic purposes.
has_obo_namespace: symptoms
id: SYMP:0000409

Axiom
annotated source: hyperthermia
annotated property: definition
annotated target: A high fever that is characterized by an exceptionally high fever especially when induced artificially for therapeutic purposes.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperthermia

neurological and physiological symptom
type: Class
subclass of: symptom
has_obo_namespace: symptoms
id: SYMP:0000410

infant symptom
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000411

anxiety
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a painful or apprehensive uneasiness of mind usually over an impending or anticipated ill.
has_obo_namespace: symptoms
id: SYMP:0000412

Axiom
annotated source: anxiety
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a painful or apprehensive uneasiness of mind usually over an impending or anticipated ill.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anxiety

catatonia
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a marked psychomotor disturbance that may involve stupor or mutism, negativism, rigidity, purposeless excitement, echolalia, echopraxia, and inappropriate or bizarre posturing and is associated with various medical conditions (as schizophrenia and mood disorders).
has_obo_namespace: symptoms
id: SYMP:0000413

Axiom
annotated source: catatonia
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a marked psychomotor disturbance that may involve stupor or mutism, negativism, rigidity, purposeless excitement, echolalia, echopraxia, and inappropriate or bizarre posturing and is associated with various medical conditions (as schizophrenia and mood disorders).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=catatonia

dysarthria
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a difficulty in articulating words due to disease of the central nervous system.
has_obo_namespace: symptoms
id: SYMP:0000414

Axiom
annotated source: dysarthria
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a difficulty in articulating words due to disease of the central nervous system.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dysarthria

amaurosis fugax
type: Class
subclass of: amaurosis
has_obo_namespace: symptoms
id: SYMP:0000415

amaurosis
type: Class
subclass of: loss of vision
has_obo_namespace: symptoms
id: SYMP:0000416

pupil symptom
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000417

contracted pupil
type: Class
subclass of: pupil symptom
has_obo_namespace: symptoms
id: SYMP:0000418

miosis
type: Class
subclass of: contracted pupil
has_obo_namespace: symptoms
id: SYMP:0000419

bloating
type: Class
subclass of: digestive system symptom
definition: Bloating is a digestive system symptom involving the accumulation of gas in the digestive tract and resulting in abdominal distension.
has_obo_namespace: symptoms
id: SYMP:0000420

Axiom
annotated source: bloating
annotated property: definition
annotated target: Bloating is a digestive system symptom involving the accumulation of gas in the digestive tract and resulting in abdominal distension.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bloating

hematochezia
type: Class
subclass of: feces and droppings symptom
has_obo_namespace: symptoms
id: SYMP:0000421

dyspepsia
type: Class
subclass of: digestive system symptom
definition: Dyspepsia is a digestive system symptom referred to as indigestion resulting from an impairment to digestion caused by ulcer, gall bladder disease or inflamed colon. Related symptoms include weakness, loss of appetite, and depression.
has_exact_synonym: indigestion
has_obo_namespace: symptoms
id: SYMP:0000422
comment: doid/symp duplicate

Axiom
annotated source: dyspepsia
annotated property: definition
annotated target: Dyspepsia is a digestive system symptom referred to as indigestion resulting from an impairment to digestion caused by ulcer, gall bladder disease or inflamed colon. Related symptoms include weakness, loss of appetite, and depression.
database_cross_reference: url:http://www.rootsweb.ancestry.com/~vapage2/deathcauses.htm

pyrosis
type: Class
subclass of: digestive system symptom
definition: From synonym: Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus.
has_alternative_id: SYMP:0000439
has_exact_synonym: acid indigestion
has_exact_synonym: heartburn
has_obo_namespace: symptoms
id: SYMP:0000423

Axiom
annotated source: pyrosis
annotated property: definition
annotated target: From synonym: Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus.
database_cross_reference: url:https://medlineplus.gov/heartburn.html

claudication
type: Class
subclass of: pain
definition: A pain that is characterized by a leg pain in the calf, or thigh, which is caused by inadequate blood flow to the leg muscles and is brought on by leg exercise such as walking.
has_exact_synonym: blockage of leg arteries
has_obo_namespace: symptoms
id: SYMP:0000424

Axiom
annotated source: claudication
annotated property: definition
annotated target: A pain that is characterized by a leg pain in the calf, or thigh, which is caused by inadequate blood flow to the leg muscles and is brought on by leg exercise such as walking.
database_cross_reference: url:http://www.nature.com/nrd/journal/v2/n1/glossary/nrd985_glossary.html
database_cross_reference: url:http://www.vasculardoc.net/content/glossary.html

reticulocytosis
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000425

macrocytosis
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000426

obsolete impotence
type: Class
definition: A reproductive system symptom that is characterized by an abnormal physical or psychological state of a male characterized by inability to copulate because of failure to have, or maintain, an erection.
has_exact_synonym: erectile dysfunction
has_obo_namespace: symptoms
id: SYMP:0000427
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete impotence
annotated property: definition
annotated target: A reproductive system symptom that is characterized by an abnormal physical or psychological state of a male characterized by inability to copulate because of failure to have, or maintain, an erection.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=impotence

hypoventilation
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by a deficient ventilation of the lungs that results in reduction in the oxygen content or increase in the carbon dioxide content of the blood or both.
has_obo_namespace: symptoms
id: SYMP:0000428

Axiom
annotated source: hypoventilation
annotated property: definition
annotated target: A respiratory abnormality that is characterized by a deficient ventilation of the lungs that results in reduction in the oxygen content or increase in the carbon dioxide content of the blood or both.

bradypnea
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by abnormally slow breathing.
has_exact_synonym: abnormally slow breathing
has_obo_namespace: symptoms
id: SYMP:0000429

Axiom
annotated source: bradypnea
annotated property: definition
annotated target: A respiratory abnormality that is characterized by abnormally slow breathing.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradypnea

pleuritic chest pain
type: Class
subclass of: chest pain
definition: A chest pain that is characterized by an inflammation of the pleural cavity with a sharp pain resulting from the exansion of the lungs as the inflammed pleural layers rub against each other.
has_obo_namespace: symptoms
id: SYMP:0000430

Axiom
annotated source: pleuritic chest pain
annotated property: definition
annotated target: A chest pain that is characterized by an inflammation of the pleural cavity with a sharp pain resulting from the exansion of the lungs as the inflammed pleural layers rub against each other.
database_cross_reference: url:http://en.wikipedia.org/wiki/Pleuritic_chest_pain
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pleurisy

sputum
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by matter discharged from the air passages in diseases of the lungs, bronchi, or upper respiratory tract that contains mucus and often pus, blood, fibrin, or bacterial products.
has_exact_synonym: sputum production
has_obo_namespace: symptoms
id: SYMP:0000431

Axiom
annotated source: sputum
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by matter discharged from the air passages in diseases of the lungs, bronchi, or upper respiratory tract that contains mucus and often pus, blood, fibrin, or bacterial products.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sputum

itching
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an uneasy irritating sensation in the upper surface of the skin usually held to result from mild stimulation of pain receptors.
has_exact_synonym: pruritus
has_obo_namespace: symptoms
id: SYMP:0000432

Axiom
annotated source: itching
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an uneasy irritating sensation in the upper surface of the skin usually held to result from mild stimulation of pain receptors.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=itching

anasarca
type: Class
subclass of: edema
definition: Anasarca is a edema characterized as generalized edema with accumulation of serum in the connective tissue.
has_exact_synonym: generalized edema
has_obo_namespace: symptoms
id: SYMP:0000433

Axiom
annotated source: anasarca
annotated property: definition
annotated target: Anasarca is a edema characterized as generalized edema with accumulation of serum in the connective tissue.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anasarca

urticaria
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by raised red skin wheals (welts) commonly caused by an allergic reaction with wheals that may vary in size from about 5 mm (0.2 inches) in diameter to the size of a dinner plate that are described as severely itchy a stingnig or burning sensation, and having a pale border.
has_exact_synonym: hives
has_exact_synonym: nettle rash
has_exact_synonym: uredo
has_obo_namespace: symptoms
id: SYMP:0000434
comment: doid/symp duplicate

Axiom
annotated source: urticaria
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by raised red skin wheals (welts) commonly caused by an allergic reaction with wheals that may vary in size from about 5 mm (0.2 inches) in diameter to the size of a dinner plate that are described as severely itchy a stingnig or burning sensation, and having a pale border.
database_cross_reference: url:http://en.wikipedia.org/wiki/Urticaria

paresthesia
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a sensation of pricking, tingling, or creeping on the skin having no objective cause and usually associated with injury or irritation of a sensory nerve or nerve root.
has_obo_namespace: symptoms
id: SYMP:0000435

Axiom
annotated source: paresthesia
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a sensation of pricking, tingling, or creeping on the skin having no objective cause and usually associated with injury or irritation of a sensory nerve or nerve root.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=paresthesia

abnormal vaginal bleeding
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by bleeding from the uterus that is longer than usual or that occurs at an irregular time. Bleeding may be heavier or lighter than usual and occur often or randomly.
has_exact_synonym: abnormal menstruation
has_obo_namespace: symptoms
id: SYMP:0000436

Axiom
annotated source: abnormal vaginal bleeding
annotated property: definition
annotated target: A reproductive system symptom that is characterized by bleeding from the uterus that is longer than usual or that occurs at an irregular time. Bleeding may be heavier or lighter than usual and occur often or randomly.
database_cross_reference: url:https://medlineplus.gov/ency/article/000903.htm

earache
type: Class
subclass of: pain
has_obo_namespace: symptoms
id: SYMP:0000437

toothache
type: Class
subclass of: pain
definition: A pain that is characterized by a pain in, or about, a tooth or teeth.
has_obo_namespace: symptoms
id: SYMP:0000438

Axiom
annotated source: toothache
annotated property: definition
annotated target: A pain that is characterized by a pain in, or about, a tooth or teeth.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/toothache

obsolete heartburn
type: Class
definition: Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus.
has_exact_synonym: acid indigestion
has_obo_namespace: symptoms
id: SYMP:0000439
deprecated: true

Axiom
annotated source: obsolete heartburn
annotated property: definition
annotated target: Heartburn is a pain characterized by a painful burning feeling in your chest or throat that happens when stomach acid backs up into your esophagus.
database_cross_reference: url:http://www.nlm.nih.gov/medlineplus/heartburn.html

hair loss
type: Class
subclass of: hair symptom
definition: A hair symptom that is characterized by the stopping of hair growth (regeneration), which may be a result of hereditary hair loss, immune system overreacts, drugs and treatments, harsh hair-care products, and other factors.
has_obo_namespace: symptoms
id: SYMP:0000440

Axiom
annotated source: hair loss
annotated property: definition
annotated target: A hair symptom that is characterized by the stopping of hair growth (regeneration), which may be a result of hereditary hair loss, immune system overreacts, drugs and treatments, harsh hair-care products, and other factors.
database_cross_reference: url:https://www.aad.org/public/diseases/hair-loss/insider/shedding

elbow pain
type: Class
subclass of: joint pain
definition: A joint pain that is characterized by a pain situated, or occurring, in or around the elbow.
has_obo_namespace: symptoms
id: SYMP:0000441

Axiom
annotated source: elbow pain
annotated property: definition
annotated target: A joint pain that is characterized by a pain situated, or occurring, in or around the elbow.
database_cross_reference: url:https://medlineplus.gov/ency/article/003172.htm

knee pain
type: Class
subclass of: joint pain
definition: A joint pain that is characterized by a pain situated, or occurring, in or around the knee.
has_obo_namespace: symptoms
id: SYMP:0000442

Axiom
annotated source: knee pain
annotated property: definition
annotated target: A joint pain that is characterized by a pain situated, or occurring, in or around the knee.
database_cross_reference: url:https://medlineplus.gov/ency/article/003187.htm

shoulder pain
type: Class
subclass of: joint pain
definition: A joint pain that is characterized by a pain situated, or occurring, in or around the shoulder.
has_obo_namespace: symptoms
id: SYMP:0000443

Axiom
annotated source: shoulder pain
annotated property: definition
annotated target: A joint pain that is characterized by a pain situated, or occurring, in or around the shoulder.
database_cross_reference: url:https://medlineplus.gov/ency/article/003171.htm

nail discoloration
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000444

obsolete faint
type: Class
definition: Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain.
has_exact_synonym: fainting
has_exact_synonym: syncope
has_obo_namespace: symptoms
id: SYMP:0000445
deprecated: true

Axiom
annotated source: obsolete faint
annotated property: definition
annotated target: Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain.
database_cross_reference: url:http://www.merriam-webster.com/dictionary/fainting

bloodshot eye
type: Class
subclass of: eye symptom
has_exact_synonym: red eye
has_exact_synonym: redness of eye
has_obo_namespace: symptoms
id: SYMP:0000446

bloody sputum
type: Class
subclass of: sputum
definition: A sputum that is characterized by blood or bloody mucus discharged from the air passages caused by common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung.
has_obo_namespace: symptoms
id: SYMP:0000447
comment: Bloody sputum (spitting up blood or bloody mucus) can come from common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung.

Axiom
annotated source: bloody sputum
annotated property: definition
annotated target: A sputum that is characterized by blood or bloody mucus discharged from the air passages caused by common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung.
database_cross_reference: url:http://www.medicinenet.com/symptoms_and_signs/article.htm
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sputum

epistaxis
type: Class
subclass of: nose symptom
definition: A nose symptom that involves a is loss of blood from the tissue lining the nose.
database_cross_reference: ICD9CM_2005:784.7
database_cross_reference: UMLS_CUI:C0014591
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0055387
has_exact_synonym: nosebleed
has_obo_namespace: symptoms
id: SYMP:0000448

Axiom
annotated source: epistaxis
annotated property: definition
annotated target: A nose symptom that involves a is loss of blood from the tissue lining the nose.
database_cross_reference: url:http://www.nlm.nih.gov/medlineplus/ency/article/003106.htm

cardiogenic shock
type: Class
subclass of: shock
database_cross_reference: ICD9CM_2005:785.51
database_cross_reference: UMLS_CUI:C0036980
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243814
has_obo_namespace: symptoms
id: SYMP:0000449

shock
type: Class
subclass of: cardiovascular system symptom
definition: A cardiovascular system symptom that is characterized as a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery.
database_cross_reference: ICD9CM_2005:785.5
database_cross_reference: UMLS_CUI:C0159051
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284197
has_obo_namespace: symptoms
id: SYMP:0000450

Axiom
annotated source: shock
annotated property: definition
annotated target: A cardiovascular system symptom that is characterized as a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery.
database_cross_reference: url:http://www.merriam-webster.com/medlineplus/shock

septic shock
type: Class
subclass of: shock
database_cross_reference: ICD9CM_2005:785.52
database_cross_reference: UMLS_CUI:C0036983
has_obo_namespace: symptoms
id: SYMP:0000451

abnormal sputum
type: Class
subclass of: sputum
database_cross_reference: ICD9CM_2005:786.4
database_cross_reference: UMLS_CUI:C0159054
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284206
has_obo_namespace: symptoms
id: SYMP:0000452

right upper quadrant abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.41
database_cross_reference: UMLS_CUI:C0375565
has_obo_namespace: symptoms
id: SYMP:0000453

abdominal rigidity
type: Class
subclass of: abdominal symptom
database_cross_reference: ICD9CM_2005:789.4
database_cross_reference: ICD9CM_2005:789.40
database_cross_reference: UMLS_CUI:C0159066
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284272
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637149
has_obo_namespace: symptoms
id: SYMP:0000454

abnormal weight gain
type: Class
subclass of: weight gain
definition: A weight gain that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying.
database_cross_reference: ICD9CM_2005:783.1
database_cross_reference: UMLS_CUI:C0332544
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243789
has_obo_namespace: symptoms
id: SYMP:0000455

Axiom
annotated source: abnormal weight gain
annotated property: definition
annotated target: A weight gain that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/abnormal

left upper quadrant abdominal pain
type: Class
subclass of: abdominal pain
definition: An abdominal pain that is characterized by occurring in the left upper quadrant abdominal pain of the abdomen that can be caused by a stomach ulcer, acute gastritis, a viral infection, or indigestion, or may be an issue with one's lungs.
database_cross_reference: ICD9CM_2005:789.02
database_cross_reference: UMLS_CUI:C0238552
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637133
has_obo_namespace: symptoms
id: SYMP:0000456

Axiom
annotated source: left upper quadrant abdominal pain
annotated property: definition
annotated target: An abdominal pain that is characterized by occurring in the left upper quadrant abdominal pain of the abdomen that can be caused by a stomach ulcer, acute gastritis, a viral infection, or indigestion, or may be an issue with one's lungs.
database_cross_reference: url:https://www.buoyhealth.com/learn/pain-upper-left-abdomen

abdominal pain
type: Class
subclass of: pain
definition: A pain that is characterized by occurring in the abdomen, i.e. between the chest and groin.
database_cross_reference: ICD9CM_2005:789.0
database_cross_reference: ICD9CM_2005:789.00
database_cross_reference: UMLS_CUI:C0000737
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0387333
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637138
has_obo_namespace: symptoms
id: SYMP:0000457

Axiom
annotated source: abdominal pain
annotated property: definition
annotated target: A pain that is characterized by occurring in the abdomen, i.e. between the chest and groin.
database_cross_reference: url:https://medlineplus.gov/ency/article/003120.htm

nausea
type: Class
subclass of: digestive system symptom
definition: Nausea is a digestive system symptom characterized by an uneasy or unsettled feeling in the stomach together with an urge to vomit.
database_cross_reference: ICD9CM_2005:787.02
database_cross_reference: UMLS_CUI:C0375548
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0750850
has_obo_namespace: symptoms
id: SYMP:0000458

Axiom
annotated source: nausea
annotated property: definition
annotated target: Nausea is a digestive system symptom characterized by an uneasy or unsettled feeling in the stomach together with an urge to vomit.
database_cross_reference: url:http://www.nlm.nih.gov/medlineplus/nauseaandvomiting.html

digestive system symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:787
database_cross_reference: UMLS_CUI:C0159058
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284224
has_obo_namespace: symptoms
id: SYMP:0000459

hepatomegaly
type: Class
subclass of: liver symptom
database_cross_reference: ICD9CM_2005:789.1
database_cross_reference: UMLS_CUI:C0019209
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0067592
has_exact_synonym: enlargement of the liver
has_obo_namespace: symptoms
id: SYMP:0000460

abdominal symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:789
database_cross_reference: ICD9CM_2005:789.9
database_cross_reference: UMLS_CUI:C0159065
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284267
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284268
has_obo_namespace: symptoms
id: SYMP:0000461

symptom
type: Class
definition: A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
has_obo_namespace: symptoms
id: SYMP:0000462

Axiom
annotated source: symptom
annotated property: definition
annotated target: A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease.
database_cross_reference: url:https://link.springer.com/chapter/10.1007/978-1-4615-4789-1_5
database_cross_reference: url:https://www.merriam-webster.com/dictionary/symptom
database_cross_reference: url:https://www.nature.com/subjects/signs-and-symptoms

lack of normal physiological development
type: Class
subclass of: lack of expected normal physiological development in childhood
database_cross_reference: ICD9CM_2005:783.40
database_cross_reference: UMLS_CUI:C0878706
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1892807
has_obo_namespace: symptoms
id: SYMP:0000463

lack of expected normal physiological development in childhood
type: Class
subclass of: nutrition, metabolism, and development symptom
database_cross_reference: ICD9CM_2005:783.4
database_cross_reference: UMLS_CUI:C0878753
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1892806
has_obo_namespace: symptoms
id: SYMP:0000464

failure to thrive
type: Class
subclass of: lack of expected normal physiological development in childhood
definition: A lack of expected normal physiological development in childhood that is characterized by a decelerated or arrested physical growth (height and weight measurements fall below the third or fifth percentile, or a downward change in growth across two major growth percentiles) and is associated with abnormal growth and development.
database_cross_reference: ICD9CM_2005:783.41
database_cross_reference: UMLS_CUI:C0015544
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0700791
has_obo_namespace: symptoms
id: SYMP:0000465

Axiom
annotated source: failure to thrive
annotated property: definition
annotated target: A lack of expected normal physiological development in childhood that is characterized by a decelerated or arrested physical growth (height and weight measurements fall below the third or fifth percentile, or a downward change in growth across two major growth percentiles) and is associated with abnormal growth and development.
database_cross_reference: url:https://www.chop.edu/conditions-diseases/failure-thrive

delayed milestones
type: Class
subclass of: lack of expected normal physiological development in childhood
definition: A lack of expected normal physiological development in childhood that is characterized by a failure for a child to reach a significant stage at the predicted age and may include walking or talking.
database_cross_reference: ICD9CM_2005:783.42
database_cross_reference: UMLS_CUI:C0476241
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1594577
has_exact_synonym: developmental delay
has_obo_namespace: symptoms
id: SYMP:0000466

Axiom
annotated source: delayed milestones
annotated property: definition
annotated target: A lack of expected normal physiological development in childhood that is characterized by a failure for a child to reach a significant stage at the predicted age and may include walking or talking.
database_cross_reference: url:https://en.wikipedia.org/wiki/Delayed_milestone

right lower quadrant abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.43
database_cross_reference: UMLS_CUI:C0375567
has_obo_namespace: symptoms
id: SYMP:0000467

generalized abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.47
database_cross_reference: UMLS_CUI:C0375571
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637142
has_obo_namespace: symptoms
id: SYMP:0000468

epigastric abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.46
database_cross_reference: UMLS_CUI:C0375570
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637141
has_obo_namespace: symptoms
id: SYMP:0000469

left upper quadrant abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.42
database_cross_reference: UMLS_CUI:C0375566
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637144
has_obo_namespace: symptoms
id: SYMP:0000470

multiple sites abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.49
database_cross_reference: UMLS_CUI:C0375572
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637145
has_obo_namespace: symptoms
id: SYMP:0000471

early satiety
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a feeling of being full after a few bites of food, or before you finish a normal-sized meal.
database_cross_reference: ICD9CM_2005:780.94
database_cross_reference: UMLS_CUI:C0239233
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2797496
has_obo_namespace: symptoms
id: SYMP:0000472

Axiom
annotated source: early satiety
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a feeling of being full after a few bites of food, or before you finish a normal-sized meal.
database_cross_reference: url:https://www.healthline.com/health/satiety-early

nutrition, metabolism, and development symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:783
database_cross_reference: UMLS_CUI:C0159041
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284163
has_obo_namespace: symptoms
id: SYMP:0000473

obsolete abnormal loss of weight and underweight
type: Class
database_cross_reference: ICD9CM_2005:783.2
database_cross_reference: UMLS_CUI:C0878752
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1892727
has_obo_namespace: symptoms
id: SYMP:0000474
deprecated: true

underweight
type: Class
subclass of: weight symptom
definition: A weight symptom that is characterized by weighing less than the normal amount for one's age, height, and build.
database_cross_reference: ICD9CM_2005:783.22
database_cross_reference: UMLS_CUI:C0041667
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0468826
has_obo_namespace: symptoms
id: SYMP:0000475

Axiom
annotated source: underweight
annotated property: definition
annotated target: A weight symptom that is characterized by weighing less than the normal amount for one's age, height, and build.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/underweight

obsolete loss of weight
type: Class
term replaced by: weight loss
has_alternative_id: SYMP:0000178
database_cross_reference: ICD9CM_2005:783.21
database_cross_reference: UMLS_CUI:C0043096
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1605347
has_exact_synonym: weight loss
has_obo_namespace: symptoms
id: SYMP:0000476
comment: This term has been replaced by weight loss.
deprecated: true

epigastric abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.36
database_cross_reference: UMLS_CUI:C0375562
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637121
has_obo_namespace: symptoms
id: SYMP:0000477

abdominal swelling
type: Class
subclass of: abdominal symptom
database_cross_reference: ICD9CM_2005:789.3
database_cross_reference: UMLS_CUI:C0476310
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243858
has_obo_namespace: symptoms
id: SYMP:0000478

abnormality of gait
type: Class
subclass of: musculoskeletal system symptom
definition: Abnormality of gait is a nervous system and musculoskeletal system symptom characterized by a difficulty in the manner of walking or moving on foot.
database_cross_reference: ICD9CM_2005:781.2
database_cross_reference: UMLS_CUI:C0575081
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243767
has_obo_namespace: symptoms
id: SYMP:0000479

Axiom
annotated source: abnormality of gait
annotated property: definition
annotated target: Abnormality of gait is a nervous system and musculoskeletal system symptom characterized by a difficulty in the manner of walking or moving on foot.
database_cross_reference: url:http://www.merriam-webster.com/dictionary/gait

nervous system symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:781
database_cross_reference: UMLS_CUI:C0159033
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284131
has_obo_namespace: symptoms
id: SYMP:0000480

persistent vegetative state
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by an individual with severe brain damage being in a state of partial arousal rather than true awareness. After four weeks in a vegetative state, the patient is classified as being in a persistent vegetative state. After three months in the US and six months in the UK, the diagnosis is classified as a permanent vegetative state after a non-traumatic brain injury, or, one year after a traumatic injury.
database_cross_reference: ICD9CM_2005:780.03
database_cross_reference: UMLS_CUI:C0242670
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0446160
has_obo_namespace: symptoms
id: SYMP:0000481

Axiom
annotated source: persistent vegetative state
annotated property: definition
annotated target: An alteration of consciousness that is characterized by an individual with severe brain damage being in a state of partial arousal rather than true awareness. After four weeks in a vegetative state, the patient is classified as being in a persistent vegetative state. After three months in the US and six months in the UK, the diagnosis is classified as a permanent vegetative state after a non-traumatic brain injury, or, one year after a traumatic injury.
database_cross_reference: url:https://en.wikipedia.org/wiki/Persistent_vegetative_state

alteration of consciousness
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by any condition which is significantly different from a normal waking state.
database_cross_reference: ICD9CM_2005:780.0
database_cross_reference: UMLS_CUI:C0234428
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0389211
has_obo_namespace: symptoms
id: SYMP:0000482

Axiom
annotated source: alteration of consciousness
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by any condition which is significantly different from a normal waking state.
database_cross_reference: url:https://en.wikipedia.org/wiki/Altered_state_of_consciousness

left lower quadrant abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.64
database_cross_reference: UMLS_CUI:C0238565
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637155
has_obo_namespace: symptoms
id: SYMP:0000483

abdominal tenderness
type: Class
subclass of: abdominal symptom
database_cross_reference: ICD9CM_2005:789.6
database_cross_reference: ICD9CM_2005:789.60
database_cross_reference: UMLS_CUI:C0232498
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0387353
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637161
has_obo_namespace: symptoms
id: SYMP:0000484

dysuria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the difficult, or painful, discharge of urine.
database_cross_reference: ICD9CM_2005:788.1
database_cross_reference: UMLS_CUI:C0013428
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0004041
has_exact_synonym: difficult urine discharge
has_exact_synonym: painful urine discharge
has_obo_namespace: symptoms
id: SYMP:0000485

Axiom
annotated source: dysuria
annotated property: definition
annotated target: A urinary system symptom that is characterized by the difficult, or painful, discharge of urine.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dysuria

urinary system symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:788
database_cross_reference: UMLS_CUI:C0476293
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284245
has_obo_namespace: symptoms
id: SYMP:0000486

rash
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an eruption on the body typically with little or no elevation above the surface.
database_cross_reference: ICD9CM_2005:782.1
database_cross_reference: UMLS_CUI:C0015230
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243780
has_exact_synonym: erythema
has_exact_synonym: rubor
has_exact_synonym: skin eruption
has_exact_synonym: skin rash
has_exact_synonym: skin redness
has_obo_namespace: symptoms
id: SYMP:0000487

Axiom
annotated source: rash
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an eruption on the body typically with little or no elevation above the surface.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=rash

skin and integumentary tissue symptom
type: Class
subclass of: symptom
definition: A skin and integumentary tissue symptom that is characterized by the outer layer of the skin starting to replace itself. Often, this happens when skin is damaged, either by disease or injury.
database_cross_reference: ICD9CM_2005:782
database_cross_reference: ICD9CM_2005:782.9
database_cross_reference: UMLS_CUI:C0159037
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284146
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284161
has_obo_namespace: symptoms
id: SYMP:0000488

Axiom
annotated source: skin and integumentary tissue symptom
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by the outer layer of the skin starting to replace itself. Often, this happens when skin is damaged, either by disease or injury.
database_cross_reference: url:https://www.medicinenet.com/peeling_skin/symptoms.htm
database_cross_reference: url:https://www.webmd.com/skin-problems-and-treatments/what-know-about-peeling-skin-desquamation

abnormal bowel sound
type: Class
subclass of: digestive system symptom
database_cross_reference: ICD9CM_2005:787.5
database_cross_reference: UMLS_CUI:C0159060
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284234
has_obo_namespace: symptoms
id: SYMP:0000489

multiple sites abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.69
database_cross_reference: UMLS_CUI:C0375574
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637157
has_obo_namespace: symptoms
id: SYMP:0000490

continuous leakage of urine
type: Class
subclass of: urinary incontinence
database_cross_reference: ICD9CM_2005:788.37
database_cross_reference: UMLS_CUI:C0375553
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0679310
has_obo_namespace: symptoms
id: SYMP:0000491

urinary incontinence
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the an inability of the body to control the evacuative functions.
database_cross_reference: ICD9CM_2005:788.3
database_cross_reference: ICD9CM_2005:788.30
database_cross_reference: UMLS_CUI:C0042024
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0814766
database_cross_reference: UMLS_ICD9CM_2005_AUI:A6994675
has_exact_synonym: incontinence
has_obo_namespace: symptoms
id: SYMP:0000492

Axiom
annotated source: urinary incontinence
annotated property: definition
annotated target: A urinary system symptom that is characterized by the an inability of the body to control the evacuative functions.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=incontinence

dysphagia
type: Class
subclass of: throat symptom
database_cross_reference: ICD9CM_2005:787.2
database_cross_reference: UMLS_CUI:C0011168
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0052114
has_exact_synonym: difficulty in swallowing
has_exact_synonym: difficulty swallowing
has_exact_synonym: impaired swallowing
has_obo_namespace: symptoms
id: SYMP:0000493

renal colic
type: Class
subclass of: colic
definition: A colic that is characterized by a severe pain produced by the passage of a calculus from the kidney through the ureter.
database_cross_reference: ICD9CM_2005:788.0
database_cross_reference: UMLS_CUI:C0152169
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0265344
has_obo_namespace: symptoms
id: SYMP:0000494

Axiom
annotated source: renal colic
annotated property: definition
annotated target: A colic that is characterized by a severe pain produced by the passage of a calculus from the kidney through the ureter.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=renal%20colic

urethral discharge
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by abnormal purulent or mucoid secretions from the penis or, rarely, the female urethra.
database_cross_reference: ICD9CM_2005:788.7
database_cross_reference: UMLS_CUI:C0152447
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0266251
has_obo_namespace: symptoms
id: SYMP:0000495

Axiom
annotated source: urethral discharge
annotated property: definition
annotated target: A urinary system symptom that is characterized by abnormal purulent or mucoid secretions from the penis or, rarely, the female urethra.

epigastric abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.66
database_cross_reference: UMLS_CUI:C0239280
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637153
has_obo_namespace: symptoms
id: SYMP:0000496

periumbilic abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.65
database_cross_reference: UMLS_CUI:C0375573
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637158
has_obo_namespace: symptoms
id: SYMP:0000497

generalized abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.67
database_cross_reference: UMLS_CUI:C0302540
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637154
has_obo_namespace: symptoms
id: SYMP:0000498

right upper quadrant abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.61
database_cross_reference: UMLS_CUI:C0238571
has_obo_namespace: symptoms
id: SYMP:0000499

right lower quadrant abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.63
database_cross_reference: UMLS_CUI:C0238570
has_obo_namespace: symptoms
id: SYMP:0000500

left lower quadrant abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.34
database_cross_reference: UMLS_CUI:C0375560
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637123
has_obo_namespace: symptoms
id: SYMP:0000501

mixed incontinence (female) (male)
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by urine leakage when you sneeze, cough, laugh, do jarring exercise, or lift something heavy. It is typically a combination of stress and urge incontinence.
database_cross_reference: ICD9CM_2005:788.33
database_cross_reference: UMLS_CUI:C0375550
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0745756
has_obo_namespace: symptoms
id: SYMP:0000502

Axiom
annotated source: mixed incontinence (female) (male)
annotated property: definition
annotated target: A urinary incontinence that is characterized by urine leakage when you sneeze, cough, laugh, do jarring exercise, or lift something heavy. It is typically a combination of stress and urge incontinence.
database_cross_reference: url:https://www.webmd.com/urinary-incontinence-oab/mixed-incontinence
comment: url:https://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence

adult failure to thrive
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a physical decline in health seen in older adults – typically those with multiple chronic medical conditions – resulting in decreased appetite and poor nutrition, weight loss, inactivity, often accompanied by dehydration, depression, decreasing functional ability, and impaired immune function.
database_cross_reference: ICD9CM_2005:783.7
database_cross_reference: UMLS_CUI:C1268580
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1892736
has_obo_namespace: symptoms
id: SYMP:0000503

Axiom
annotated source: adult failure to thrive
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a physical decline in health seen in older adults – typically those with multiple chronic medical conditions – resulting in decreased appetite and poor nutrition, weight loss, inactivity, often accompanied by dehydration, depression, decreasing functional ability, and impaired immune function.
database_cross_reference: url:https://www.compassus.com/for-caregivers/what-is-adult-failure-to-thrive
database_cross_reference: url:https://www.uptodate.com/contents/failure-to-thrive-in-older-adults-evaluation

headache
type: Class
subclass of: pain
definition: A pain that is characterized by a pain in the head.
database_cross_reference: ICD9CM_2005:784.0
database_cross_reference: UMLS_CUI:C0018681
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0065994
has_exact_synonym: cephalalgia
has_obo_namespace: symptoms
id: SYMP:0000504

Axiom
annotated source: headache
annotated property: definition
annotated target: A pain that is characterized by a pain in the head.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=headache

throat pain
type: Class
subclass of: pain
definition: A pain that is characterized by a painful throat due to inflammation of the fauces and pharynx.
database_cross_reference: ICD9CM_2005:784.1
database_cross_reference: UMLS_CUI:C0242429
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284175
has_exact_synonym: sore throat
has_obo_namespace: symptoms
id: SYMP:0000505

Axiom
annotated source: throat pain
annotated property: definition
annotated target: A pain that is characterized by a painful throat due to inflammation of the fauces and pharynx.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sore%20throat

hemorrhage from throat
type: Class
subclass of: throat symptom
database_cross_reference: ICD9CM_2005:784.8
database_cross_reference: UMLS_CUI:C0576995
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284188
has_obo_namespace: symptoms
id: SYMP:0000506

head swelling
type: Class
subclass of: head symptom
database_cross_reference: ICD9CM_2005:784.2
database_cross_reference: UMLS_CUI:C0159045
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284180
has_obo_namespace: symptoms
id: SYMP:0000507

aphasia
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a loss or impairment of the power to use or comprehend words usually resulting from brain damage.
database_cross_reference: ICD9CM_2005:784.3
database_cross_reference: UMLS_CUI:C0003537
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0025556
has_exact_synonym: inability to comprehend language
has_obo_namespace: symptoms
id: SYMP:0000508
comment: doid/symp duplicate

Axiom
annotated source: aphasia
annotated property: definition
annotated target: A nervous system symptom that is characterized by a loss or impairment of the power to use or comprehend words usually resulting from brain damage.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=aphasia

flatulence
type: Class
subclass of: digestive system symptom
has_alternative_id: SYMP:0000708
database_cross_reference: ICD9CM_2005:787.3
database_cross_reference: UMLS_CUI:C0016205
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243846
has_exact_synonym: gas
has_exact_synonym: gas production
has_obo_namespace: symptoms
id: SYMP:0000509

pallor
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a deficiency of color especially of the face.
database_cross_reference: ICD9CM_2005:782.61
database_cross_reference: UMLS_CUI:C0030232
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0096956
has_exact_synonym: paleness
has_obo_namespace: symptoms
id: SYMP:0000510

Axiom
annotated source: pallor
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a deficiency of color especially of the face.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pallor

flushing
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a markedly red flush in a persons face and often other areas of the skin, from various physiological conditions. Flushing is generally distinguished, despite a close physiological relation between them, from blushing, which is milder, generally restricted to the face or cheeks, and generally assumed to reflect embarrassment. Flushing is also a cardinal symptom of carcinoid syndrome the syndrome that results from hormones (often serotonin or histamine) being secreted into systemic circulation.
database_cross_reference: ICD9CM_2005:782.62
database_cross_reference: UMLS_CUI:C0016382
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0060138
has_obo_namespace: symptoms
id: SYMP:0000511

Axiom
annotated source: flushing
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a markedly red flush in a persons face and often other areas of the skin, from various physiological conditions. Flushing is generally distinguished, despite a close physiological relation between them, from blushing, which is milder, generally restricted to the face or cheeks, and generally assumed to reflect embarrassment. Flushing is also a cardinal symptom of carcinoid syndrome the syndrome that results from hormones (often serotonin or histamine) being secreted into systemic circulation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Flushing_%28physiology%29

male stress incontinence
type: Class
subclass of: stress incontinence
definition: A stress incontinence that is characterized by a compromised external urinary sphincter muscle resulting from surgical or radiotherapeutic manipulation.
database_cross_reference: ICD9CM_2005:788.32
database_cross_reference: UMLS_CUI:C0302505
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0800441
has_obo_namespace: symptoms
id: SYMP:0000512

Axiom
annotated source: male stress incontinence
annotated property: definition
annotated target: A stress incontinence that is characterized by a compromised external urinary sphincter muscle resulting from surgical or radiotherapeutic manipulation.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356867/

stridor
type: Class
subclass of: abnormal chest sound
definition: An abnormal chest sound that is characterized by a harsh vibrating sound heard during respiration in cases of obstruction of the air passages.
database_cross_reference: ICD9CM_2005:786.1
database_cross_reference: UMLS_CUI:C0038450
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0120146
has_obo_namespace: symptoms
id: SYMP:0000513

Axiom
annotated source: stridor
annotated property: definition
annotated target: An abnormal chest sound that is characterized by a harsh vibrating sound heard during respiration in cases of obstruction of the air passages.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stridor

respiratory system and chest symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:786
database_cross_reference: UMLS_CUI:C0476271
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284200
has_obo_namespace: symptoms
id: SYMP:0000514

hiccough
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a spasmodic inhalation with closure of the glottis accompanied by a peculiar sound.
database_cross_reference: ICD9CM_2005:786.8
database_cross_reference: UMLS_CUI:C0019521
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0421293
has_obo_namespace: symptoms
id: SYMP:0000515

Axiom
annotated source: hiccough
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a spasmodic inhalation with closure of the glottis accompanied by a peculiar sound.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hiccough

lump in chest
type: Class
subclass of: respiratory system and chest symptom
database_cross_reference: ICD9CM_2005:786.6
database_cross_reference: UMLS_CUI:C0159055
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284217
has_obo_namespace: symptoms
id: SYMP:0000516

hemoptysis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an expectoration of blood from some part of the respiratory tract.
database_cross_reference: ICD9CM_2005:786.3
database_cross_reference: UMLS_CUI:C0019079
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0067232
has_exact_synonym: coughing up of blood
has_exact_synonym: expectoration of blood
has_exact_synonym: expectoration of blood-stained sputum
has_exact_synonym: haemoptysis
has_obo_namespace: symptoms
id: SYMP:0000517

Axiom
annotated source: hemoptysis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an expectoration of blood from some part of the respiratory tract.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hemoptysis

generalized abdominal pain
type: Class
subclass of: abdominal pain
definition: An abdominal pain that is characterized by being diffuse or widespread and affecting or involving all of the abdomen.
database_cross_reference: ICD9CM_2005:789.07
database_cross_reference: UMLS_CUI:C0344304
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637131
has_obo_namespace: symptoms
id: SYMP:0000518

Axiom
annotated source: generalized abdominal pain
annotated property: definition
annotated target: An abdominal pain that is characterized by being diffuse or widespread and affecting or involving all of the abdomen.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/generalization
database_cross_reference: url:https://www.merriam-webster.com/dictionary/generalized

abnormal feces
type: Class
subclass of: feces and droppings symptom
database_cross_reference: ICD9CM_2005:787.7
database_cross_reference: UMLS_CUI:C0162287
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284238
has_obo_namespace: symptoms
id: SYMP:0000519

visible peristalsis
type: Class
subclass of: digestive system symptom
database_cross_reference: ICD9CM_2005:787.4
database_cross_reference: UMLS_CUI:C0159059
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284228
has_obo_namespace: symptoms
id: SYMP:0000520

enlargement of lymph nodes
type: Class
subclass of: lymphatic system symptom
database_cross_reference: ICD9CM_2005:785.6
database_cross_reference: UMLS_CUI:C0497156
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243823
has_exact_synonym: swelling of lymph nodes
has_exact_synonym: swollen lymph glands
has_obo_namespace: symptoms
id: SYMP:0000521

feeding difficulties and mismanagement
type: Class
subclass of: nutrition, metabolism, and development symptom
database_cross_reference: ICD9CM_2005:783.3
database_cross_reference: UMLS_CUI:C0699815
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284167
has_obo_namespace: symptoms
id: SYMP:0000522

anorexia
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a loss of appetite especially when prolonged.
database_cross_reference: ICD9CM_2005:783.0
database_cross_reference: UMLS_CUI:C0003123
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0024378
has_obo_namespace: symptoms
id: SYMP:0000523

Axiom
annotated source: anorexia
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a loss of appetite especially when prolonged.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anorexia

polyphagia
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by an excessive appetite or eating.
database_cross_reference: ICD9CM_2005:783.6
database_cross_reference: UMLS_CUI:C0020505
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0011381
has_obo_namespace: symptoms
id: SYMP:0000524

Axiom
annotated source: polyphagia
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by an excessive appetite or eating.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polyphagia

transient alteration of awareness
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a brief (transient) episode of losing normal awareness or behavior.
database_cross_reference: ICD9CM_2005:780.02
database_cross_reference: UMLS_CUI:C0221539
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0466980
has_obo_namespace: symptoms
id: SYMP:0000525

Axiom
annotated source: transient alteration of awareness
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a brief (transient) episode of losing normal awareness or behavior.
database_cross_reference: url:https://www.inst-neuro.com/services/epilepsy/transient-alteration-of-awareness/

ascites
type: Class
subclass of: abdominal symptom
definition: An abdominal symptom consisting of an abnormal accumulation of serous fluid in the spaces between tissues and organs in the cavity of the abdomen.
database_cross_reference: ICD9CM_2005:789.5
database_cross_reference: UMLS_CUI:C0003962
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0026882
has_exact_synonym: hydroperitoneum
has_obo_namespace: symptoms
id: SYMP:0000526

Axiom
annotated source: ascites
annotated property: definition
annotated target: An abdominal symptom consisting of an abnormal accumulation of serous fluid in the spaces between tissues and organs in the cavity of the abdomen.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ascites

undiagnosed cardiac murmur
type: Class
subclass of: cardiovascular system symptom
database_cross_reference: ICD9CM_2005:785.2
database_cross_reference: UMLS_CUI:C0375546
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0813487
has_obo_namespace: symptoms
id: SYMP:0000527

cardiovascular system symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:785
database_cross_reference: UMLS_CUI:C0159049
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284192
has_obo_namespace: symptoms
id: SYMP:0000528

tachycardia
type: Class
subclass of: arrhythmia
definition: Tachycardia is a cardiovascular system symptom consisting of a relatively rapid heart action whether physiological (as after exercise) or pathological.
database_cross_reference: ICD9CM_2005:785.0
database_cross_reference: UMLS_CUI:C0039231
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0804597
has_obo_namespace: symptoms
id: SYMP:0000529

Axiom
annotated source: tachycardia
annotated property: definition
annotated target: Tachycardia is a cardiovascular system symptom consisting of a relatively rapid heart action whether physiological (as after exercise) or pathological.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachycardia

palpitation
type: Class
subclass of: cardiovascular system symptom
definition: Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart,whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease.
database_cross_reference: ICD9CM_2005:785.1
database_cross_reference: UMLS_CUI:C0030252
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0004066
has_exact_synonym: abnormal heart beats
has_obo_namespace: symptoms
id: SYMP:0000530

Axiom
annotated source: palpitation
annotated property: definition
annotated target: Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart,whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease.
database_cross_reference: url:http://en.wikipedia.org/wiki/Palpitation
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=palpitation

splenomegaly
type: Class
subclass of: spleen symptom
database_cross_reference: ICD9CM_2005:789.2
database_cross_reference: UMLS_CUI:C0038002
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0118748
has_exact_synonym: esplenomegaly
has_obo_namespace: symptoms
id: SYMP:0000531

urge incontinence
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder when a sudden strong need to urinate is felt, even when the bladder isn't full.
database_cross_reference: ICD9CM_2005:788.31
database_cross_reference: UMLS_CUI:C0150045
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0469078
has_obo_namespace: symptoms
id: SYMP:0000532

Axiom
annotated source: urge incontinence
annotated property: definition
annotated target: A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder when a sudden strong need to urinate is felt, even when the bladder isn't full.
database_cross_reference: url:https://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence

post-void dribbling
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by urine remaining in the urethra after voiding the bladder that slowly leaks out after urination.
database_cross_reference: ICD9CM_2005:788.35
database_cross_reference: UMLS_CUI:C0375552
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0775329
has_obo_namespace: symptoms
id: SYMP:0000533

Axiom
annotated source: post-void dribbling
annotated property: definition
annotated target: A urinary incontinence that is characterized by urine remaining in the urethra after voiding the bladder that slowly leaks out after urination.
database_cross_reference: url:https://en.wikipedia.org/wiki/Post-void_dribbling

spontaneous ecchymoses
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by the spontaneous escape of blood into the tissues from ruptured blood vessels marked by a livid black-and-blue or purple spot or area.
database_cross_reference: ICD9CM_2005:782.7
database_cross_reference: UMLS_CUI:C0159039
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284153
has_obo_namespace: symptoms
id: SYMP:0000534

Axiom
annotated source: spontaneous ecchymoses
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by the spontaneous escape of blood into the tissues from ruptured blood vessels marked by a livid black-and-blue or purple spot or area.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=ecchymoses

change in skin texture
type: Class
subclass of: skin and integumentary tissue symptom
database_cross_reference: ICD9CM_2005:782.8
database_cross_reference: UMLS_CUI:C0159040
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284158
has_obo_namespace: symptoms
id: SYMP:0000535

disturbance of skin sensation
type: Class
subclass of: skin and integumentary tissue symptom
database_cross_reference: ICD9CM_2005:782.0
database_cross_reference: UMLS_CUI:C0012766
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243776
has_obo_namespace: symptoms
id: SYMP:0000536

cyanosis
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a bluish or purplish discoloration (as of skin) due to deficient oxygenation of the blood.
database_cross_reference: ICD9CM_2005:782.5
database_cross_reference: UMLS_CUI:C0010520
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0044296
has_obo_namespace: symptoms
id: SYMP:0000537

Axiom
annotated source: cyanosis
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a bluish or purplish discoloration (as of skin) due to deficient oxygenation of the blood.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cyanosis

edema
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an abnormal excess accumulation of serous fluid in connective tissue or in a serous cavity.
database_cross_reference: ICD9CM_2005:782.3
database_cross_reference: UMLS_CUI:C0013604
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0052720
has_exact_synonym: dropsy
has_obo_namespace: symptoms
id: SYMP:0000538

Axiom
annotated source: edema
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an abnormal excess accumulation of serous fluid in connective tissue or in a serous cavity.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=edema

jaundice
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a yellowish pigmentation of the skin, tissues, and certain body fluids is caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states).
database_cross_reference: ICD9CM_2005:782.4
database_cross_reference: UMLS_CUI:C0476232
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243785
has_exact_synonym: icteric
has_exact_synonym: icterus
has_obo_namespace: symptoms
id: SYMP:0000539

Axiom
annotated source: jaundice
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a yellowish pigmentation of the skin, tissues, and certain body fluids is caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=jaundice

painful respiration
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a feeling of discomfort when breathing in or out. The pain may be the result of infection, musculoskeletal injury, and heart problems.
database_cross_reference: ICD9CM_2005:786.52
database_cross_reference: UMLS_CUI:C0423729
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243833
has_obo_namespace: symptoms
id: SYMP:0000540

Axiom
annotated source: painful respiration
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a feeling of discomfort when breathing in or out. The pain may be the result of infection, musculoskeletal injury, and heart problems.
database_cross_reference: url:https://www.healthline.com/health/painful-respiration#causes
database_cross_reference: url:https://www.medicalnewstoday.com/articles/324718

periumbilic abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.35
database_cross_reference: UMLS_CUI:C0375561
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637126
has_obo_namespace: symptoms
id: SYMP:0000541

epigastric abdominal pain
type: Class
subclass of: abdominal pain
definition: An abdominal pain that is characterized by occurring in the epigastrium, i.e. the upper part of the abdomen below the rib cage.
database_cross_reference: ICD9CM_2005:789.06
database_cross_reference: UMLS_CUI:C0232493
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637130
has_obo_namespace: symptoms
id: SYMP:0000542

Axiom
annotated source: epigastric abdominal pain
annotated property: definition
annotated target: An abdominal pain that is characterized by occurring in the epigastrium, i.e. the upper part of the abdomen below the rib cage.
database_cross_reference: url:https://info.isabelhealthcare.com/blog/why-does-my-stomach-hurt-epigastric-pain-symptoms-and-causes
database_cross_reference: url:https://www.healthline.com/health/epigastric-pain

memory loss
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by an unusual forgetfulness. One may not be able to remember new events, recall one or more memories of the past, or both. Memory loss may be for a short time and then resolve (transient), or it may not go away and get worse over time.
database_cross_reference: ICD9CM_2005:780.93
database_cross_reference: UMLS_CUI:C0751295
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2797424
has_obo_namespace: symptoms
id: SYMP:0000543

Axiom
annotated source: memory loss
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by an unusual forgetfulness. One may not be able to remember new events, recall one or more memories of the past, or both. Memory loss may be for a short time and then resolve (transient), or it may not go away and get worse over time.
database_cross_reference: url:https://medlineplus.gov/ency/article/003257.htm
database_cross_reference: url:https://www.merckmanuals.com/professional/neurologic-disorders/symptoms-of-neurologic-disorders/memory-loss

transient paralysis of limb
type: Class
subclass of: paralysis
database_cross_reference: ICD9CM_2005:781.4
database_cross_reference: UMLS_CUI:C0159034
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284133
has_obo_namespace: symptoms
id: SYMP:0000544

multiple sites abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.39
database_cross_reference: UMLS_CUI:C0375564
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637125
has_obo_namespace: symptoms
id: SYMP:0000545

right lower quadrant abdominal pain
type: Class
subclass of: abdominal pain
database_cross_reference: ICD9CM_2005:789.03
database_cross_reference: UMLS_CUI:C0740603
has_obo_namespace: symptoms
id: SYMP:0000546

right upper quadrant abdominal pain
type: Class
subclass of: abdominal pain
database_cross_reference: ICD9CM_2005:789.01
database_cross_reference: UMLS_CUI:C0235299
has_obo_namespace: symptoms
id: SYMP:0000547

right lower quadrant abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.33
database_cross_reference: UMLS_CUI:C0375559
has_obo_namespace: symptoms
id: SYMP:0000548

generalized abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.37
database_cross_reference: UMLS_CUI:C0375563
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637122
has_obo_namespace: symptoms
id: SYMP:0000549

clubbing of fingers
type: Class
subclass of: musculoskeletal system symptom
database_cross_reference: ICD9CM_2005:781.5
database_cross_reference: UMLS_CUI:C0009080
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284139
has_obo_namespace: symptoms
id: SYMP:0000550

disturbances of sensation of smell and taste
type: Class
subclass of: nervous system symptom
database_cross_reference: ICD9CM_2005:781.1
database_cross_reference: UMLS_CUI:C0495689
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243765
has_exact_synonym: taste alteration
has_obo_namespace: symptoms
id: SYMP:0000551

meningismus
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a state of meningeal irritation with symptoms suggesting meningitis that often occurs at the onset of acute febrile diseases especially in children.
database_cross_reference: ICD9CM_2005:781.6
database_cross_reference: UMLS_CUI:C0025287
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0434815
has_obo_namespace: symptoms
id: SYMP:0000552

Axiom
annotated source: meningismus
annotated property: definition
annotated target: A nervous system symptom that is characterized by a state of meningeal irritation with symptoms suggesting meningitis that often occurs at the onset of acute febrile diseases especially in children.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=meningismus

neurologic neglect syndrome
type: Class
subclass of: nervous system symptom
database_cross_reference: ICD9CM_2005:781.8
database_cross_reference: UMLS_CUI:C0840927
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0752424
has_obo_namespace: symptoms
id: SYMP:0000553

left lower quadrant abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.44
database_cross_reference: UMLS_CUI:C0375568
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637143
has_obo_namespace: symptoms
id: SYMP:0000554

left upper quadrant abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.32
database_cross_reference: UMLS_CUI:C0375558
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637124
has_obo_namespace: symptoms
id: SYMP:0000555

localized superficial lump
type: Class
subclass of: skin and integumentary tissue symptom
database_cross_reference: ICD9CM_2005:782.2
database_cross_reference: UMLS_CUI:C0476228
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243783
has_obo_namespace: symptoms
id: SYMP:0000556

urinary retention
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by an inability to empty the bladder completely during the process of voiding (urination).
database_cross_reference: ICD9CM_2005:788.2
database_cross_reference: ICD9CM_2005:788.20
database_cross_reference: UMLS_CUI:C0080274
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284250
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0784422
has_exact_synonym: inability to urinate
has_exact_synonym: ischuria
has_exact_synonym: retention of urine
has_obo_namespace: symptoms
id: SYMP:0000557

Axiom
annotated source: urinary retention
annotated property: definition
annotated target: A urinary system symptom that is characterized by an inability to empty the bladder completely during the process of voiding (urination).
database_cross_reference: url:https://en.wikipedia.org/wiki/Urinary_retention

incomplete bladder emptying
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by a bladder that is not empty.
database_cross_reference: ICD9CM_2005:788.21
database_cross_reference: UMLS_CUI:C0344365
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0722424
has_obo_namespace: symptoms
id: SYMP:0000558

voice disturbance
type: Class
subclass of: mouth symptom
database_cross_reference: ICD9CM_2005:784.4
database_cross_reference: ICD9CM_2005:784.40
database_cross_reference: UMLS_CUI:C0042940
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284182
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0818015
has_obo_namespace: symptoms
id: SYMP:0000559

polydipsia
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by an excessive or abnormal thirst.
database_cross_reference: ICD9CM_2005:783.5
database_cross_reference: UMLS_CUI:C0085602
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0003974
has_obo_namespace: symptoms
id: SYMP:0000560

Axiom
annotated source: polydipsia
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by an excessive or abnormal thirst.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polydipsia

multiple sites abdominal pain
type: Class
subclass of: abdominal pain
database_cross_reference: ICD9CM_2005:789.09
database_cross_reference: UMLS_CUI:C0375555
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637134
has_obo_namespace: symptoms
id: SYMP:0000561

right upper quadrant abdominal swelling
type: Class
subclass of: abdominal swelling
database_cross_reference: ICD9CM_2005:789.31
database_cross_reference: UMLS_CUI:C0375557
has_obo_namespace: symptoms
id: SYMP:0000562

urinary frequency
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the need to urinate many times during the day, at night, or both but in normal or less-than-normal volumes. Frequency may be accompanied by a sensation of an urgent need to void (urgency of urination).
database_cross_reference: ICD9CM_2005:788.41
database_cross_reference: UMLS_CUI:C0042023
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0004030
has_exact_synonym: frequent urination
has_obo_namespace: symptoms
has_related_synonym: nocturia
id: SYMP:0000563

Axiom
annotated source: urinary frequency
annotated property: definition
annotated target: A urinary system symptom that is characterized by the need to urinate many times during the day, at night, or both but in normal or less-than-normal volumes. Frequency may be accompanied by a sensation of an urgent need to void (urgency of urination).
database_cross_reference: url:https://www.merckmanuals.com/professional/genitourinary-disorders/symptoms-of-genitourinary-disorders/urinary-frequency

nocturia
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by urination at night especially when excessive.
database_cross_reference: ICD9CM_2005:788.43
database_cross_reference: UMLS_CUI:C0028734
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0011475
has_exact_synonym: nycturia
has_obo_namespace: symptoms
id: SYMP:0000564

Axiom
annotated source: nocturia
annotated property: definition
annotated target: A urinary system symptom that is characterized by urination at night especially when excessive.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=nocturia

polyuria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the excessive secretion of urine.
database_cross_reference: ICD9CM_2005:788.42
database_cross_reference: UMLS_CUI:C0032617
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0103470
has_exact_synonym: excessive secretion of urine
has_obo_namespace: symptoms
id: SYMP:0000565

Axiom
annotated source: polyuria
annotated property: definition
annotated target: A urinary system symptom that is characterized by the excessive secretion of urine.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=polyuria

sleep disturbance
type: Class
subclass of: general symptom
database_cross_reference: ICD9CM_2005:780.5
database_cross_reference: UMLS_CUI:C0037317
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0246756
has_obo_namespace: symptoms
id: SYMP:0000566

general symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:780
database_cross_reference: UMLS_CUI:C0159028
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284119
has_obo_namespace: symptoms
id: SYMP:0000567

short stature
type: Class
subclass of: lack of expected normal physiological development in childhood
definition: A lack of expected normal physiological development in childhood that is characterized by an individual's height being in the 3rd percentile for the mean height of a given age, sex, and population group.
database_cross_reference: ICD9CM_2005:783.43
database_cross_reference: UMLS_CUI:C0349588
has_obo_namespace: symptoms
id: SYMP:0000568

Axiom
annotated source: short stature
annotated property: definition
annotated target: A lack of expected normal physiological development in childhood that is characterized by an individual's height being in the 3rd percentile for the mean height of a given age, sex, and population group.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK556031/

oliguria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the reduced excretion of urine.
database_cross_reference: ICD9CM_2005:788.5
database_cross_reference: UMLS_CUI:C0028962
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243854
has_obo_namespace: symptoms
id: SYMP:0000569

Axiom
annotated source: oliguria
annotated property: definition
annotated target: A urinary system symptom that is characterized by the reduced excretion of urine.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=oliguria

diarrhea
type: Class
subclass of: feces and droppings symptom
definition: Diarrhea is a feces and droppng symptom involving the abnormally frequent intestinal evacuations with more or less fluid stools.
database_cross_reference: ICD9CM_2005:787.91
database_cross_reference: UMLS_CUI:C0011991
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0048148
has_exact_synonym: bacterial gastroenteritis
has_exact_synonym: diarrhoea
has_exact_synonym: fecal incontinence
has_exact_synonym: incontinence of feces
has_exact_synonym: loose bowel
has_exact_synonym: loose bowels
has_exact_synonym: the runs
has_obo_namespace: symptoms
id: SYMP:0000570
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

Axiom
annotated source: diarrhea
annotated property: definition
annotated target: Diarrhea is a feces and droppng symptom involving the abnormally frequent intestinal evacuations with more or less fluid stools.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=diarrhea

insomnia
type: Class
subclass of: sleep disturbance
definition: Insomnia is a sleep disturbance characterized by prolonged and usually abnormal inability to obtain adequate sleep.
database_cross_reference: ICD9CM_2005:780.52
database_cross_reference: UMLS_CUI:C0029645
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243733
has_exact_synonym: agrypnia
has_obo_namespace: symptoms
id: SYMP:0000571

Axiom
annotated source: insomnia
annotated property: definition
annotated target: Insomnia is a sleep disturbance characterized by prolonged and usually abnormal inability to obtain adequate sleep.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=insomnia

splitting of urinary stream
type: Class
subclass of: urinary stream symptom
definition: A urinary stream symptom that is characterized by a split in the urine flow resulting in it streaming in two directions.
database_cross_reference: ICD9CM_2005:788.61
database_cross_reference: UMLS_CUI:C0232855
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0460440
has_obo_namespace: symptoms
id: SYMP:0000572

Axiom
annotated source: splitting of urinary stream
annotated property: definition
annotated target: A urinary stream symptom that is characterized by a split in the urine flow resulting in it streaming in two directions.
database_cross_reference: url:https://ugatl.com/services/prostatitis/splitting-urine-stream/

urinary stream symptom
type: Class
subclass of: urinary system symptom
database_cross_reference: ICD9CM_2005:788.6
database_cross_reference: ICD9CM_2005:788.69
database_cross_reference: UMLS_CUI:C0159063
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284254
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284255
has_obo_namespace: symptoms
id: SYMP:0000573

aphonia
type: Class
subclass of: voice disturbance
database_cross_reference: ICD9CM_2005:784.41
database_cross_reference: UMLS_CUI:C0003564
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0025595
has_obo_namespace: symptoms
id: SYMP:0000574

precordial pain
type: Class
subclass of: chest pain
database_cross_reference: ICD9CM_2005:786.51
database_cross_reference: UMLS_CUI:C0232286
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284212
has_obo_namespace: symptoms
id: SYMP:0000575

chest pain
type: Class
subclass of: pain
database_cross_reference: ICD9CM_2005:786.5
database_cross_reference: ICD9CM_2005:786.50
database_cross_reference: UMLS_CUI:C0008031
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243830
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0400627
has_obo_namespace: symptoms
id: SYMP:0000576

fussy infant
type: Class
subclass of: infant symptom
database_cross_reference: ICD9CM_2005:780.91
database_cross_reference: UMLS_CUI:C1135254
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2358677
has_obo_namespace: symptoms
id: SYMP:0000577

incontinence without sensory awareness
type: Class
subclass of: urinary incontinence
database_cross_reference: ICD9CM_2005:788.34
database_cross_reference: UMLS_CUI:C0375551
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0722462
has_obo_namespace: symptoms
id: SYMP:0000578

insomnia with sleep apnea
type: Class
subclass of: insomnia
database_cross_reference: ICD9CM_2005:780.51
database_cross_reference: UMLS_CUI:C0159030
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284123
has_obo_namespace: symptoms
id: SYMP:0000579

dysfunctions associated with sleep stages
type: Class
subclass of: sleep disturbance
database_cross_reference: ICD9CM_2005:780.56
database_cross_reference: UMLS_CUI:C0013373
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243741
has_obo_namespace: symptoms
id: SYMP:0000580

sleep apnea
type: Class
subclass of: apnea
definition: An apnea that is characterized by brief periods of recurrent cessation of breathing during sleep that is caused especially by obstruction of the airway or a disturbance in the brain's respiratory center and is associated especially with excessive daytime sleepiness.
database_cross_reference: ICD9CM_2005:780.57
database_cross_reference: UMLS_CUI:C0375544
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0760143
has_obo_namespace: symptoms
id: SYMP:0000581
comment: doid/symp duplicate

Axiom
annotated source: sleep apnea
annotated property: definition
annotated target: An apnea that is characterized by brief periods of recurrent cessation of breathing during sleep that is caused especially by obstruction of the airway or a disturbance in the brain's respiratory center and is associated especially with excessive daytime sleepiness.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sleep%20apnea

hypersomnia
type: Class
subclass of: sleep disturbance
definition: Hypersomnia is a sleep disturbance characterized by sleeping for excessive periods at intervals with intervening periods of normal duration of sleeping and waking.
database_cross_reference: ICD9CM_2005:780.54
database_cross_reference: UMLS_CUI:C0029637
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243739
has_obo_namespace: symptoms
id: SYMP:0000582

Axiom
annotated source: hypersomnia
annotated property: definition
annotated target: Hypersomnia is a sleep disturbance characterized by sleeping for excessive periods at intervals with intervening periods of normal duration of sleeping and waking.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypersomnia

hypersomnia with sleep apnea
type: Class
subclass of: hypersomnia
database_cross_reference: ICD9CM_2005:780.53
database_cross_reference: UMLS_CUI:C0020530
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243735
has_obo_namespace: symptoms
id: SYMP:0000583

disruptions of 24-hour sleep-wake cycle
type: Class
subclass of: sleep disturbance
database_cross_reference: ICD9CM_2005:780.55
database_cross_reference: UMLS_CUI:C0159031
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284127
has_obo_namespace: symptoms
id: SYMP:0000584

sleep related movement disorder
type: Class
subclass of: sleep disturbance
database_cross_reference: ICD9CM_2005:780.58
database_cross_reference: UMLS_CUI:C1455873
database_cross_reference: UMLS_ICD9CM_2005_AUI:A6995224
has_obo_namespace: symptoms
id: SYMP:0000585

overflow incontinence
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by a bladder that does not empty completely, resulting in a bladder that is too full, which leads to overflow and unexpected leaking.
database_cross_reference: ICD9CM_2005:788.38
database_cross_reference: UMLS_CUI:C0312413
database_cross_reference: UMLS_ICD9CM_2005_AUI:A6994689
has_obo_namespace: symptoms
id: SYMP:0000586

Axiom
annotated source: overflow incontinence
annotated property: definition
annotated target: A urinary incontinence that is characterized by a bladder that does not empty completely, resulting in a bladder that is too full, which leads to overflow and unexpected leaking.
database_cross_reference: url:https://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence
database_cross_reference: url:https://www.healthline.com/health/overactive-bladder/overflow-incontinence
database_cross_reference: url:https://www.webmd.com/urinary-incontinence-oab/overflow-incontinence

abnormal chest sound
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a sound of breathing that is not similar to that of the sound of moving air and may include: rhonchi (a low-pitched breath sound), crackles (a high-pitched breath sound), wheezing (a high-pitched whistling sound caused by narrowing of the bronchial tubes), and stridor (a harsh, vibratory sound caused by narrowing of the upper airway).
database_cross_reference: ICD9CM_2005:786.7
database_cross_reference: UMLS_CUI:C0159056
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284219
has_obo_namespace: symptoms
id: SYMP:0000587

Axiom
annotated source: abnormal chest sound
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a sound of breathing that is not similar to that of the sound of moving air and may include: rhonchi (a low-pitched breath sound), crackles (a high-pitched breath sound), wheezing (a high-pitched whistling sound caused by narrowing of the bronchial tubes), and stridor (a harsh, vibratory sound caused by narrowing of the upper airway).
database_cross_reference: url:https://www.healthline.com/health/breath-sounds#types

extravasation of urine
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by an injury of the urethra in its bulbous or membranous portion, which leads to a collection of urine in other cavities, such as the perineal space, the scrotum, the penis and the connective tissue of the anterior abdominal wall.
database_cross_reference: ICD9CM_2005:788.8
database_cross_reference: UMLS_CUI:C0152245
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284259
has_obo_namespace: symptoms
id: SYMP:0000588

Axiom
annotated source: extravasation of urine
annotated property: definition
annotated target: A urinary system symptom that is characterized by an injury of the urethra in its bulbous or membranous portion, which leads to a collection of urine in other cavities, such as the perineal space, the scrotum, the penis and the connective tissue of the anterior abdominal wall.
database_cross_reference: url:https://en.wikipedia.org/wiki/Extravasation_of_urine
database_cross_reference: url:https://jamanetwork.com/journals/jama/article-abstract/466994

slowing of urinary stream
type: Class
subclass of: urinary stream symptom
definition: A urinary stream symptom that is characterized by a slow or weak stream of urine.
database_cross_reference: ICD9CM_2005:788.62
database_cross_reference: UMLS_CUI:C0232854
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0459374
has_obo_namespace: symptoms
id: SYMP:0000589

Axiom
annotated source: slowing of urinary stream
annotated property: definition
annotated target: A urinary stream symptom that is characterized by a slow or weak stream of urine.
database_cross_reference: url:https://www.besturologistnyc.com/what-is-slow-urine-flow

urinary urgency
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by a strong and immediate need to urinate due to an increase in pressure in the bladder, resulting in difficulty to hold in the urine. This can occur regardless of whether the bladder is full.
database_cross_reference: ICD9CM_2005:788.63
database_cross_reference: UMLS_CUI:C0085606
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2797703
has_exact_synonym: urgency of urination
has_obo_namespace: symptoms
id: SYMP:0000590

Axiom
annotated source: urinary urgency
annotated property: definition
annotated target: A urinary system symptom that is characterized by a strong and immediate need to urinate due to an increase in pressure in the bladder, resulting in difficulty to hold in the urine. This can occur regardless of whether the bladder is full.
database_cross_reference: url:https://www.medicalnewstoday.com/articles/325336#symptoms

left upper quadrant abdominal tenderness
type: Class
subclass of: abdominal tenderness
database_cross_reference: ICD9CM_2005:789.62
database_cross_reference: UMLS_CUI:C0238566
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637156
has_obo_namespace: symptoms
id: SYMP:0000591

excessive crying of infant
type: Class
subclass of: infant symptom
database_cross_reference: ICD9CM_2005:780.92
database_cross_reference: UMLS_CUI:C0497134
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2358671
has_obo_namespace: symptoms
id: SYMP:0000592

gangrene
type: Class
subclass of: cardiovascular system symptom
database_cross_reference: ICD9CM_2005:785.4
database_cross_reference: UMLS_CUI:C0017086
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0061978
has_obo_namespace: symptoms
id: SYMP:0000593

abnormal involuntary movement
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an inability to control bodily movement and may be a symptom of cerebrovascular diseases, dyskinesia, tremor, chorea, dystonia and myoclonus.
database_cross_reference: ICD9CM_2005:781.0
database_cross_reference: UMLS_CUI:C0392702
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243762
has_obo_namespace: symptoms
id: SYMP:0000594

Axiom
annotated source: abnormal involuntary movement
annotated property: definition
annotated target: A nervous system symptom that is characterized by an inability to control bodily movement and may be a symptom of cerebrovascular diseases, dyskinesia, tremor, chorea, dystonia and myoclonus.
database_cross_reference: url:https://patient.info/doctor/abnormal-involuntary-movements
database_cross_reference: url:https://stanfordmedicine25.stanford.edu/the25/involuntary-movements-and-tremors.html

febrile convulsion
type: Class
subclass of: convulsion
definition: A convulsion that is characterized by occurring in young children between six months and five years of age and which is triggered by fever.
database_cross_reference: ICD9CM_2005:780.31
database_cross_reference: UMLS_CUI:C0009952
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0701466
has_exact_synonym: febrile seizure
has_obo_namespace: symptoms
id: SYMP:0000595

Axiom
annotated source: febrile convulsion
annotated property: definition
annotated target: A convulsion that is characterized by occurring in young children between six months and five years of age and which is triggered by fever.
database_cross_reference: url:https://www.ninds.nih.gov/febrile-seizures-fact-sheet
database_cross_reference: url:https://www.webmd.com/a-to-z-guides/swollen-glands

convulsion
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an abnormal violent and involuntary contraction or series of contractions of the muscles.
database_cross_reference: ICD9CM_2005:780.3
database_cross_reference: UMLS_CUI:C0009951
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0042665
has_obo_namespace: symptoms
id: SYMP:0000596

Axiom
annotated source: convulsion
annotated property: definition
annotated target: A nervous system symptom that is characterized by an abnormal violent and involuntary contraction or series of contractions of the muscles.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/convulsion

head and neck symptom
type: Class
subclass of: symptom
database_cross_reference: ICD9CM_2005:784
database_cross_reference: UMLS_CUI:C0476247
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284173
has_obo_namespace: symptoms
id: SYMP:0000597

respiratory abnormality
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a respiration that is not normal and may include, but is not limited to: apnea, eupnea, orthopnea, dyspnea hyperpnea, hyperventilation, hypoventilation, tachypnea, Kussmaul respiration, Cheyne-Stokes respiration, sighing respiration, Biot respiration, apneustic breathing, central neurogenic hyperventilation, and central neurogenic hypoventilation.
database_cross_reference: ICD9CM_2005:786.0
database_cross_reference: UMLS_CUI:C0159053
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0284202
has_obo_namespace: symptoms
id: SYMP:0000598

Axiom
annotated source: respiratory abnormality
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a respiration that is not normal and may include, but is not limited to: apnea, eupnea, orthopnea, dyspnea hyperpnea, hyperventilation, hypoventilation, tachypnea, Kussmaul respiration, Cheyne-Stokes respiration, sighing respiration, Biot respiration, apneustic breathing, central neurogenic hyperventilation, and central neurogenic hypoventilation.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK470309/

cheyne-stokes respiration
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by a specific form of periodic breathing (waxing and waning amplitude of flow or tidal volume) characterized by a crescendo-decrescendo pattern of respiration between central apneas or central hypopneas.
database_cross_reference: ICD9CM_2005:786.04
database_cross_reference: UMLS_CUI:C0008039
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0400651
has_obo_namespace: symptoms
id: SYMP:0000599

Axiom
annotated source: cheyne-stokes respiration
annotated property: definition
annotated target: A respiratory abnormality that is characterized by a specific form of periodic breathing (waxing and waning amplitude of flow or tidal volume) characterized by a crescendo-decrescendo pattern of respiration between central apneas or central hypopneas.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK448165/

apnea
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by transient cessation of respiration whether normal (as in hibernating animals) or abnormal (as that caused by certain drugs).
database_cross_reference: ICD9CM_2005:786.03
database_cross_reference: UMLS_CUI:C0003578
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0025648
has_obo_namespace: symptoms
id: SYMP:0000600

Axiom
annotated source: apnea
annotated property: definition
annotated target: A respiratory abnormality that is characterized by transient cessation of respiration whether normal (as in hibernating animals) or abnormal (as that caused by certain drugs).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=apnea

hyperventilation
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by excessive ventilation characterized by excessive rate and depth of respiration leading to abnormal loss of carbon dioxide from the blood.
database_cross_reference: ICD9CM_2005:786.01
database_cross_reference: UMLS_CUI:C0020578
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0071094
has_obo_namespace: symptoms
id: SYMP:0000601

Axiom
annotated source: hyperventilation
annotated property: definition
annotated target: A respiratory abnormality that is characterized by excessive ventilation characterized by excessive rate and depth of respiration leading to abnormal loss of carbon dioxide from the blood.

orthopnea
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by a difficulty in breathing that occurs when lying down and is relieved upon changing to an upright position (as in congestive heart failure).
database_cross_reference: ICD9CM_2005:786.02
database_cross_reference: UMLS_CUI:C0085619
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0004140
has_obo_namespace: symptoms
id: SYMP:0000602

Axiom
annotated source: orthopnea
annotated property: definition
annotated target: A respiratory abnormality that is characterized by a difficulty in breathing that occurs when lying down and is relieved upon changing to an upright position (as in congestive heart failure).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=orthopnea

tachypnea
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by an increased rate of respiration and shallow breathing.
has_alternative_id: SYMP:0000683
database_cross_reference: ICD9CM_2005:786.06
database_cross_reference: UMLS_CUI:C0231835
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0465027
has_exact_synonym: rapid breathing
has_obo_namespace: symptoms
id: SYMP:0000603

Axiom
annotated source: tachypnea
annotated property: definition
annotated target: A respiratory abnormality that is characterized by an increased rate of respiration and shallow breathing.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachypnea
database_cross_reference: url:https://www.healthline.com/health/rapid-shallow-breathing

wheezing
type: Class
subclass of: abnormal chest sound
definition: An abnormal chest sound that is characterized by breathing with difficulty usually with a whistling sound.
database_cross_reference: ICD9CM_2005:786.07
database_cross_reference: UMLS_CUI:C0043144
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0133941
has_obo_namespace: symptoms
id: SYMP:0000604

Axiom
annotated source: wheezing
annotated property: definition
annotated target: An abnormal chest sound that is characterized by breathing with difficulty usually with a whistling sound.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=wheezing

coma
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions.
database_cross_reference: ICD9CM_2005:780.01
database_cross_reference: UMLS_CUI:C0009421
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0041160
has_obo_namespace: symptoms
id: SYMP:0000605

Axiom
annotated source: coma
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions.
database_cross_reference: url:https://en.wikipedia.org/wiki/Coma

nocturnal enuresis
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by involuntary urination at night in children five years of age or older.
database_cross_reference: ICD9CM_2005:788.36
database_cross_reference: UMLS_CUI:C0270327
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0753297
has_exact_synonym: bed wetting
has_exact_synonym: nighttime incontinence
has_obo_namespace: symptoms
id: SYMP:0000606

Axiom
annotated source: nocturnal enuresis
annotated property: definition
annotated target: A urinary incontinence that is characterized by involuntary urination at night in children five years of age or older.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348193/

hallucination
type: Class
subclass of: general symptom
definition: Hallucination is a general symptom where there is a perception of something (as a visual image or a sound) with no external cause usually arising from a disorder of the nervous system (as in delirium tremens or in functional psychosis without known neurological disease) or in response to drugs (as LSD).
database_cross_reference: ICD9CM_2005:780.1
database_cross_reference: UMLS_CUI:C0018524
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0065642
has_obo_namespace: symptoms
id: SYMP:0000607

Axiom
annotated source: hallucination
annotated property: definition
annotated target: Hallucination is a general symptom where there is a perception of something (as a visual image or a sound) with no external cause usually arising from a disorder of the nervous system (as in delirium tremens or in functional psychosis without known neurological disease) or in response to drugs (as LSD).
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hallucinations

syncope and collapse
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain and limb weakness progressing to collapse.
database_cross_reference: ICD9CM_2005:780.2
database_cross_reference: UMLS_CUI:C0039070
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243721
has_obo_namespace: symptoms
id: SYMP:0000608

Axiom
annotated source: syncope and collapse
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a loss of consciousness resulting from insufficient blood flow to the brain and limb weakness progressing to collapse.
database_cross_reference: url:https://en.wikipedia.org/wiki/Syncope_(medicine)

generalized hyperhidrosis
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by excessive sweating, i.e. the production of more sweat than is required to regulate body temperature. Generalized hyperhidrosis is caused by non-thermoregulatory stimuli and affects the entire body.
database_cross_reference: ICD9CM_2005:780.8
database_cross_reference: UMLS_CUI:C0476476
database_cross_reference: UMLS_ICD9CM_2005_AUI:A6994739
has_exact_synonym: secondary hyperhidrosis
has_obo_namespace: symptoms
id: SYMP:0000609

Axiom
annotated source: generalized hyperhidrosis
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by excessive sweating, i.e. the production of more sweat than is required to regulate body temperature. Generalized hyperhidrosis is caused by non-thermoregulatory stimuli and affects the entire body.
database_cross_reference: url:https://sydneynorthneurology.com.au/generalised-hyperhidrosis/

dizziness
type: Class
subclass of: balance symptom
definition: A balance symptom that is characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head.
database_cross_reference: ICD9CM_2005:780.4
database_cross_reference: UMLS_CUI:C0476206
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243727
has_exact_synonym: dizzy
has_obo_namespace: symptoms
id: SYMP:0000610

Axiom
annotated source: dizziness
annotated property: definition
annotated target: A balance symptom that is characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dizziness

periumbilic abdominal pain
type: Class
subclass of: abdominal pain
database_cross_reference: ICD9CM_2005:789.05
database_cross_reference: UMLS_CUI:C0740594
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637135
has_obo_namespace: symptoms
id: SYMP:0000611

periumbilic abdominal rigidity
type: Class
subclass of: abdominal rigidity
database_cross_reference: ICD9CM_2005:789.45
database_cross_reference: UMLS_CUI:C0375569
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637146
has_obo_namespace: symptoms
id: SYMP:0000612

fever
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a rise of body temperature above the normal, whether as a natural response (as to infection) or artificially induced for therapeutic reasons.
database_cross_reference: ICD9CM_2005:780.6
database_cross_reference: UMLS_CUI:C0015967
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0058972
has_exact_synonym: pyrexia
has_obo_namespace: symptoms
id: SYMP:0000613

Axiom
annotated source: fever
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a rise of body temperature above the normal, whether as a natural response (as to infection) or artificially induced for therapeutic reasons.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=fever

cough
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance.
database_cross_reference: ICD9CM_2005:786.2
database_cross_reference: UMLS_CUI:C0010200
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0043303
has_obo_namespace: symptoms
id: SYMP:0000614

Axiom
annotated source: cough
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=cough

obsolete lack of coordination
type: Class
term replaced by: incoordination
database_cross_reference: ICD9CM_2005:781.3
database_cross_reference: UMLS_CUI:C0520966
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243769
has_obo_namespace: symptoms
id: SYMP:0000615
deprecated: true

loss of height
type: Class
subclass of: musculoskeletal system symptom
database_cross_reference: ICD9CM_2005:781.91
database_cross_reference: UMLS_CUI:C0424641
database_cross_reference: UMLS_ICD9CM_2005_AUI:A1892812
has_obo_namespace: symptoms
id: SYMP:0000616

torticollis
type: Class
subclass of: musculoskeletal system symptom
database_cross_reference: ICD9CM_2005:781.93
database_cross_reference: UMLS_CUI:C0028856
database_cross_reference: UMLS_ICD9CM_2005_AUI:A2358774
has_exact_synonym: twisted neck
has_exact_synonym: wry neck
has_obo_namespace: symptoms
id: SYMP:0000617

abnormal posture
type: Class
subclass of: musculoskeletal system symptom
database_cross_reference: ICD9CM_2005:781.92
database_cross_reference: UMLS_CUI:C0231471
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0387502
has_obo_namespace: symptoms
id: SYMP:0000618

tetany
type: Class
subclass of: musculoskeletal system symptom
database_cross_reference: ICD9CM_2005:781.7
database_cross_reference: UMLS_CUI:C0039621
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0124526
has_obo_namespace: symptoms
id: SYMP:0000619

left lower quadrant abdominal pain
type: Class
subclass of: abdominal pain
definition: An abdominal pain that is characterized by occurring in the left lower quadrant of the abdomen that is often related to the digestive tract, but can also be related to conditions of the body wall, skin, blood vessels, urinary tract, or reproductive organs.
database_cross_reference: ICD9CM_2005:789.04
database_cross_reference: UMLS_CUI:C0238551
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0637132
has_obo_namespace: symptoms
id: SYMP:0000620

Axiom
annotated source: left lower quadrant abdominal pain
annotated property: definition
annotated target: An abdominal pain that is characterized by occurring in the left lower quadrant of the abdomen that is often related to the digestive tract, but can also be related to conditions of the body wall, skin, blood vessels, urinary tract, or reproductive organs.
database_cross_reference: url:https://www.healthgrades.com/right-care/symptoms-and-conditions/left-lower-quadrant-pain

alexia
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by a loss of ability to read.
database_cross_reference: ICD9CM_2005:784.6
database_cross_reference: ICD9CM_2005:784.69
database_cross_reference: UMLS_CUI:C0478145
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243803
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243804
has_obo_namespace: symptoms
id: SYMP:0000621
comment: doid/symp duplicate

Axiom
annotated source: alexia
annotated property: definition
annotated target: An aphasia that is characterized by a loss of ability to read.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=alexia

acute mesenteric lymphadenitis
type: Class
subclass of: lymphadenitis
has_obo_namespace: symptoms
id: SYMP:0000622

acute renal failure
type: Class
subclass of: renal failure
definition: A renal failure that is characterized by a severe and sudden onset of renal failure.
has_obo_namespace: symptoms
id: SYMP:0000623

obsolete appendicitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0000624
deprecated: true

conscious disturbance
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a disturbance in sentience (the ability to experience feelings and sensations) or awareness of one's internal and external existence, i.e. inhibited or absent self-awareness.
has_obo_namespace: symptoms
id: SYMP:0000625

Axiom
annotated source: conscious disturbance
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a disturbance in sentience (the ability to experience feelings and sensations) or awareness of one's internal and external existence, i.e. inhibited or absent self-awareness.
database_cross_reference: url:https://en.wikipedia.org/wiki/Consciousness
database_cross_reference: url:https://en.wikipedia.org/wiki/Disorders_of_consciousness

disturbed vision
type: Class
subclass of: vision distortion
has_exact_synonym: disturbance of vision
has_obo_namespace: symptoms
id: SYMP:0000627

vision distortion
type: Class
subclass of: vision symptom
has_obo_namespace: symptoms
id: SYMP:0000628

exanthema
type: Class
subclass of: rash
definition: A rash characterized by a widespread skin eruption usually occurring in children that is a symptom of a more general disease.
has_obo_namespace: symptoms
id: SYMP:0000629

Axiom
annotated source: exanthema
annotated property: definition
annotated target: A rash characterized by a widespread skin eruption usually occurring in children that is a symptom of a more general disease.
database_cross_reference: url:http://en.wikipedia.org/wiki/Exanthema

frontal headache
type: Class
subclass of: headache
has_obo_namespace: symptoms
id: SYMP:0000630

hemolytic anemia
type: Class
subclass of: anemia
has_obo_namespace: symptoms
id: SYMP:0000631
comment: doid/symp duplicate

hip pain
type: Class
subclass of: joint pain
definition: A joint pain that is characterized by a pain situated, or occurring, in or around the hip.
has_obo_namespace: symptoms
id: SYMP:0000632

Axiom
annotated source: hip pain
annotated property: definition
annotated target: A joint pain that is characterized by a pain situated, or occurring, in or around the hip.
database_cross_reference: url:https://medlineplus.gov/ency/article/003179.htm

inflammatory low back pain
type: Class
subclass of: backache
has_obo_namespace: symptoms
id: SYMP:0000633

leukocytosis
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000634

low backache
type: Class
subclass of: backache
has_exact_synonym: low back pain
has_obo_namespace: symptoms
id: SYMP:0000635

maculopapular rash
type: Class
subclass of: rash
definition: A rash characterized by papule(s), which are a raised area of the skin and macule(s), which are a flat red area of the skin.
has_obo_namespace: symptoms
id: SYMP:0000636

Axiom
annotated source: maculopapular rash
annotated property: definition
annotated target: A rash characterized by papule(s), which are a raised area of the skin and macule(s), which are a flat red area of the skin.
database_cross_reference: url:https://www.webmd.com/skin-problems-and-treatments/what-is-maculopapular-rash

opisthotonus
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000637

papular rash
type: Class
subclass of: rash
definition: A rash characterized by papule(s), which are a raised area of the skin.
has_obo_namespace: symptoms
id: SYMP:0000638

Axiom
annotated source: papular rash
annotated property: definition
annotated target: A rash characterized by papule(s), which are a raised area of the skin.
database_cross_reference: url:https://www.webmd.com/skin-problems-and-treatments/what-is-maculopapular-rash

rectorrhagia
type: Class
subclass of: digestive system symptom
has_exact_synonym: rectal bleeding
has_obo_namespace: symptoms
id: SYMP:0000639

ankle rash
type: Class
subclass of: rash
definition: A rash characterized by an inflammatory reaction of the skin on the ankles.
has_exact_synonym: redness of ankle
has_obo_namespace: symptoms
id: SYMP:0000640

Axiom
annotated source: ankle rash
annotated property: definition
annotated target: A rash characterized by an inflammatory reaction of the skin on the ankles.
database_cross_reference: url:https://www.healthgrades.com/right-care/skin-hair-and-nails/ankle-rash

renal involvement
type: Class
subclass of: urinary system symptom
has_obo_namespace: symptoms
id: SYMP:0000641

obsolete respiratory distress
type: Class
has_obo_namespace: symptoms
id: SYMP:0000642
deprecated: true

respiratory failure
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a difficulty to breathe on one's own and develops when the lungs cannot get enough oxygen into the blood.
has_exact_synonym: respiratory dysfunction
has_obo_namespace: symptoms
id: SYMP:0000643
comment: doid/symp duplicate - reviewed 10/2022, both DO & SYMP

Axiom
annotated source: respiratory failure
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a difficulty to breathe on one's own and develops when the lungs cannot get enough oxygen into the blood.
database_cross_reference: url:https://www.nhlbi.nih.gov/health/respiratory-failure

ruffled feather
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000644

obsolete ankle swelling
type: Class
has_obo_namespace: symptoms
id: SYMP:0000645
deprecated: true

synovitis
type: Class
subclass of: joint inflammation
definition: Synovitis is a joint inflammation characterized by an inflammation of a synovial membrane usually with pain and swelling of the joint.
has_obo_namespace: symptoms
id: SYMP:0000646
comment: doid/symp duplicate

Axiom
annotated source: synovitis
annotated property: definition
annotated target: Synovitis is a joint inflammation characterized by an inflammation of a synovial membrane usually with pain and swelling of the joint.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=synovitis

tache noire
type: Class
subclass of: skin ulcer
definition: A skin ulcer that is characterized by a a small dark-centered ulcer that appears at the site of a tick bite and is the primary lesion of boutonneuse fever.
has_obo_namespace: symptoms
id: SYMP:0000647

Axiom
annotated source: tache noire
annotated property: definition
annotated target: A skin ulcer that is characterized by a a small dark-centered ulcer that appears at the site of a tick bite and is the primary lesion of boutonneuse fever.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tache%20noire

tenesmus
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000648

terminal ileitis
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000649

thick white exudate on tongue
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000650

discharge
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000651

wound discharge
type: Class
subclass of: discharge
has_obo_namespace: symptoms
id: SYMP:0000652

yellow dropping
type: Class
subclass of: feces and droppings symptom
has_obo_namespace: symptoms
id: SYMP:0000653

irritability
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by a quick excitability to annoyance, impatience, or anger.
has_exact_synonym: Inconsolability
has_obo_namespace: symptoms
id: SYMP:0000654

Axiom
annotated source: irritability
annotated property: definition
annotated target: A behavioral symptom that is characterized by a quick excitability to annoyance, impatience, or anger.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=irritability

mouth bleeding
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000655

pale mucous membrane
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000656

ischemic necrosis of jejunum
type: Class
subclass of: necrosis of jejunum
has_obo_namespace: symptoms
id: SYMP:0000657

extraocular muscles paralysis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000658

pareses
type: Class
subclass of: paralysis
definition: A paralysis that is charachterized by a slight or partial paralysis.
has_exact_synonym: partial paralysis
has_obo_namespace: symptoms
id: SYMP:0000659

Axiom
annotated source: pareses
annotated property: definition
annotated target: A paralysis that is charachterized by a slight or partial paralysis.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pareses

purpuric rash
type: Class
subclass of: rash
definition: A rash characterized by a red or purple hued small spots of blood appear on the skin caused by conditions that result in blood leaking into the skin and other body surfaces that does not fade when pressed upon.
has_obo_namespace: symptoms
id: SYMP:0000660

Axiom
annotated source: purpuric rash
annotated property: definition
annotated target: A rash characterized by a red or purple hued small spots of blood appear on the skin caused by conditions that result in blood leaking into the skin and other body surfaces that does not fade when pressed upon.
database_cross_reference: url:https://en.wikipedia.org/wiki/Purpura
database_cross_reference: url:https://patient.info/allergies-blood-immune/blood-clotting-tests/purpuric-rashes

recumbency
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000661

shakes
type: Class
subclass of: general symptom
definition: Shakes is a general symptom characterized by a condition of trembling.
has_exact_synonym: trembling
has_obo_namespace: symptoms
id: SYMP:0000662

Axiom
annotated source: shakes
annotated property: definition
annotated target: Shakes is a general symptom characterized by a condition of trembling.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=shakes

uncoordinated gait
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000663

yellow exudate from nose
type: Class
subclass of: nose symptom
has_obo_namespace: symptoms
id: SYMP:0000664

yellow exudate from eyes
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000665

abnormal behavior
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by behavior that is atypical or statistically uncommon within a particular culture, or that is maladaptive, or detrimental to an individual, or those around that individual.
has_obo_namespace: symptoms
id: SYMP:0000666

Axiom
annotated source: abnormal behavior
annotated property: definition
annotated target: A behavioral symptom that is characterized by behavior that is atypical or statistically uncommon within a particular culture, or that is maladaptive, or detrimental to an individual, or those around that individual.
database_cross_reference: url:https://www.betterhelp.com/advice/behavior/what-is-abnormal-behavior/

abnormal hemistanding
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000669

abnormal hemiwalking
type: Class
subclass of: postural reaction
has_obo_namespace: symptoms
id: SYMP:0000670

sudden onset of fever
type: Class
subclass of: fever
has_obo_namespace: symptoms
id: SYMP:0000671

abscess
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000672

bradykinesia
type: Class
subclass of: hypokinesia
definition: Bradykinesia is a hypokinesia characterized by an extreme slowness in the execution of movements and reflexes.
has_obo_namespace: symptoms
id: SYMP:0000673

Axiom
annotated source: bradykinesia
annotated property: definition
annotated target: Bradykinesia is a hypokinesia characterized by an extreme slowness in the execution of movements and reflexes.
database_cross_reference: url:http://en.wikipedia.org/wiki/Bradykinesia
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bradykinesia

acute cranial nerve dysfunction
type: Class
subclass of: neurological dysfunction
has_obo_namespace: symptoms
id: SYMP:0000674

acute diarrhea
type: Class
subclass of: diarrhea
definition: Acute diarrhea is a diarrhea with either or both a rapid onset or a short course.
has_obo_namespace: symptoms
id: SYMP:0000675
comment: doid/symp duplicate

Axiom
annotated source: acute diarrhea
annotated property: definition
annotated target: Acute diarrhea is a diarrhea with either or both a rapid onset or a short course.
database_cross_reference: url:http://en.wikipedia.org/wiki/Acute_%28medicine%29
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=diarrhea

acute enteritis
type: Class
subclass of: enteritis
definition: Acute enteritis is a enteritis with either or both a rapid onset and a short course which is usually due to bacteria or virus.
has_obo_namespace: symptoms
id: SYMP:0000676

Axiom
annotated source: acute enteritis
annotated property: definition
annotated target: Acute enteritis is a enteritis with either or both a rapid onset and a short course which is usually due to bacteria or virus.
database_cross_reference: url:http://en.wikipedia.org/wiki/Acute_%28medicine%29
database_cross_reference: url:http://en.wikipedia.org/wiki/Enteritis

acute gastroenteritis
type: Class
subclass of: gastroenteritis
has_obo_namespace: symptoms
id: SYMP:0000677

acute mental dysfunction
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a severe and sudden onset of disturbance in the normal operation of one's cognition, emotional regulation, or behaviour.
has_obo_namespace: symptoms
id: SYMP:0000678

Axiom
annotated source: acute mental dysfunction
annotated property: definition
annotated target: A nervous system symptom that is characterized by a severe and sudden onset of disturbance in the normal operation of one's cognition, emotional regulation, or behaviour.
database_cross_reference: url:https://www.who.int/news-room/fact-sheets/detail/mental-disorders

acute dyspnea
type: Class
subclass of: dyspnea
definition: A dyspnea that is characterized by a severe and sudden onset.
has_obo_namespace: symptoms
id: SYMP:0000679

Axiom
annotated source: acute dyspnea
annotated property: definition
annotated target: A dyspnea that is characterized by a severe and sudden onset.
database_cross_reference: url:https://medlineplus.gov/ency/imagepages/18126.htm

acute weight loss
type: Class
subclass of: weight loss
definition: A weight loss that is characterized by a severe and sudden onset.
has_obo_namespace: symptoms
id: SYMP:0000680

Axiom
annotated source: acute weight loss
annotated property: definition
annotated target: A weight loss that is characterized by a severe and sudden onset.
database_cross_reference: url:https://medlineplus.gov/ency/imagepages/18126.htm

aggressive behavior
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by behavior aimed at harming a person, or animal, or damaging physical property.
has_obo_namespace: symptoms
id: SYMP:0000681

Axiom
annotated source: aggressive behavior
annotated property: definition
annotated target: A behavioral symptom that is characterized by behavior aimed at harming a person, or animal, or damaging physical property.
database_cross_reference: url:https://www.healthline.com/health/aggressive-behavior

altered mental status
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a host of presentations that include changes in cognition, mood, behavior, and/or level of arousal.
has_obo_namespace: symptoms
id: SYMP:0000682

Axiom
annotated source: altered mental status
annotated property: definition
annotated target: A nervous system symptom that is characterized by a host of presentations that include changes in cognition, mood, behavior, and/or level of arousal.
database_cross_reference: url:https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787028/all/Altered_Mental_Status

obsolete tachypnoea
type: Class
definition: Tachypnoea is a respiratory system and chest symptom characterized by an increased rate of respiration.
has_obo_namespace: symptoms
id: SYMP:0000683
deprecated: true

Axiom
annotated source: obsolete tachypnoea
annotated property: definition
annotated target: Tachypnoea is a respiratory system and chest symptom characterized by an increased rate of respiration.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tachypnoea

bifrontal headache
type: Class
subclass of: headache
has_obo_namespace: symptoms
id: SYMP:0000684

brain cyst
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000685

chronic cough
type: Class
subclass of: cough
definition: A cough that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance marked by long duration, by frequent recurrence over a long time, and often by slowly progressing seriousness.
has_obo_namespace: symptoms
id: SYMP:0000686

Axiom
annotated source: chronic cough
annotated property: definition
annotated target: A cough that is characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance marked by long duration, by frequent recurrence over a long time, and often by slowly progressing seriousness.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=chronic

obsolete chronic fatigue syndrome
type: Class
definition: Chronic fatigue syndrome is a fatigue characterized by a disorder of uncertain cause that is characterized by persistent profound fatigue usually accompanied by impairment in short-term memory or concentration, sore throat, tender lymph nodes, muscle or joint pain, and headache unrelated to any preexisting medical condition and that typically has an onset at about 30 years of age.
has_obo_namespace: symptoms
id: SYMP:0000687
deprecated: true

Axiom
annotated source: obsolete chronic fatigue syndrome
annotated property: definition
annotated target: Chronic fatigue syndrome is a fatigue characterized by a disorder of uncertain cause that is characterized by persistent profound fatigue usually accompanied by impairment in short-term memory or concentration, sore throat, tender lymph nodes, muscle or joint pain, and headache unrelated to any preexisting medical condition and that typically has an onset at about 30 years of age.

circling movement
type: Class
subclass of: abnormal involuntary movement
definition: An abnormal involuntary movement that is characterized by an inability to walk in a straight line.
has_obo_namespace: symptoms
id: SYMP:0000688

Axiom
annotated source: circling movement
annotated property: definition
annotated target: An abnormal involuntary movement that is characterized by an inability to walk in a straight line.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434216/

cramp
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000689

cranial nerve palsies
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000690

cytopenia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000691

low blood pressure
type: Class
subclass of: blood pressure
has_obo_namespace: symptoms
id: SYMP:0000692

decreased facial sensation
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000693

decreased jaw tone
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000694

decreased milk production
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a decrease in the production of milk in breastfeeding mothers.
has_obo_namespace: symptoms
id: SYMP:0000695

Axiom
annotated source: decreased milk production
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a decrease in the production of milk in breastfeeding mothers.
database_cross_reference: url:https://www.chop.edu/pages/low-milk-supply
database_cross_reference: url:https://www.thewomens.org.au/health-information/breastfeeding/breastfeeding-problems/low-milk-supply

decreased motor response
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000696

decreased pharyngeal tone
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000697

decreased sucking
type: Class
subclass of: feeding difficulties and mismanagement
definition: A feeding difficulties and mismanagement that is characterized by a decrease in muscle coordination to form a suck response so that the child can ingest milk.
has_obo_namespace: symptoms
id: SYMP:0000698

Axiom
annotated source: decreased sucking
annotated property: definition
annotated target: A feeding difficulties and mismanagement that is characterized by a decrease in muscle coordination to form a suck response so that the child can ingest milk.
database_cross_reference: url:https://adoption.umn.edu/sucking-problems

deltoid muscle weakness
type: Class
subclass of: muscle weakness
has_obo_namespace: symptoms
id: SYMP:0000699

diminished spontaneous movement
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000700

nasal discharge
type: Class
subclass of: nose symptom
has_obo_namespace: symptoms
id: SYMP:0000701

distended loops of intestines on rectal
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000702

droopy ears
type: Class
subclass of: ear symptom
has_obo_namespace: symptoms
id: SYMP:0000703

dysphonia
type: Class
subclass of: voice disturbance
has_obo_namespace: symptoms
id: SYMP:0000704

expressive aphasia
type: Class
subclass of: aphasia
definition: An aphasia that is characterized by damage to, or a developmental issues in, the anterior regions of the brain, including (but not limited to) the left inferior frontal region known as Broca's area. Sufferers of this form of aphasia exhibit the common problem of agrammatism. For them, speech is difficult to initiate, non-fluent, labored, and halting.
has_exact_synonym: Broca's aphasia
has_exact_synonym: agrammatic aphasia
has_obo_namespace: symptoms
id: SYMP:0000705

Axiom
annotated source: expressive aphasia
annotated property: definition
annotated target: An aphasia that is characterized by damage to, or a developmental issues in, the anterior regions of the brain, including (but not limited to) the left inferior frontal region known as Broca's area. Sufferers of this form of aphasia exhibit the common problem of agrammatism. For them, speech is difficult to initiate, non-fluent, labored, and halting.
database_cross_reference: url:http://en.wikipedia.org/wiki/Expressive_aphasia

facial weakness
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000706

flaccid muscle tone
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0000707

granulomatous inflammation
type: Class
subclass of: inflammation
has_obo_namespace: symptoms
id: SYMP:0000709

head pressing
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0000710

hind limb paralysis
type: Class
subclass of: paralysis
has_obo_namespace: symptoms
id: SYMP:0000711

infertility
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized the biological inability of a man or a woman to contribute to conception; or, the state of a woman who is unable to carry a pregnancy to full term.
has_obo_namespace: symptoms
id: SYMP:0000712
comment: doid/symp duplicate

Axiom
annotated source: infertility
annotated property: definition
annotated target: A reproductive system symptom that is characterized the biological inability of a man or a woman to contribute to conception; or, the state of a woman who is unable to carry a pregnancy to full term.
database_cross_reference: url:http://en.wikipedia.org/wiki/Infertility

inability to lie flat
type: Class
subclass of: musculoskeletal system symptom
has_obo_namespace: symptoms
id: SYMP:0000713

intraretinal hemorrhage
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000714

skin desquamation
type: Class
subclass of: skin peeling
definition: A skin and integumentary tissue symptom that is characterized by the peeling off of skin in the form of scales.
has_obo_namespace: symptoms
id: SYMP:0000715

Axiom
annotated source: skin desquamation
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by the peeling off of skin in the form of scales.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=desquamation

swelling symptom
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000716

leg swelling
type: Class
subclass of: swelling symptom
has_obo_namespace: symptoms
id: SYMP:0000717

loss of consciousness
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a state in which an individual lacks normal awareness of self and the surrounding environment and one's ability to remain awake, aware, and oriented is impaired.
has_obo_namespace: symptoms
id: SYMP:0000718

Axiom
annotated source: loss of consciousness
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a state in which an individual lacks normal awareness of self and the surrounding environment and one's ability to remain awake, aware, and oriented is impaired.
database_cross_reference: url:https://drwilderman.com/neurological-disorders/loss-of-consciousness/
database_cross_reference: url:https://www.healthline.com/health/consciousness-decreased

memory impairment
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a diminished or reduced ability to remember things such as dates and names, and increased forgetfulness.
has_obo_namespace: symptoms
id: SYMP:0000719

Axiom
annotated source: memory impairment
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a diminished or reduced ability to remember things such as dates and names, and increased forgetfulness.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/impairment

microangiopathic hemolytic anemia
type: Class
subclass of: hemolytic anemia
has_obo_namespace: symptoms
id: SYMP:0000720

moderate anemia
type: Class
subclass of: anemia
has_obo_namespace: symptoms
id: SYMP:0000721

moderate conjuctival injection
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000722

multiple abscesses
type: Class
subclass of: abscess
has_obo_namespace: symptoms
id: SYMP:0000723

multiple organ failure
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000724

necrosis of jejunum
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0000725

painful reginal lymphadenopathy
type: Class
subclass of: lymphadenopathy
has_obo_namespace: symptoms
id: SYMP:0000726

palate weakness
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000727

partial hind limb paralysis
type: Class
subclass of: hind limb paralysis
has_obo_namespace: symptoms
id: SYMP:0000728

pulmonary consolidation
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a region of normally compressible lung tissue that has filled with liquid instead of air.
has_obo_namespace: symptoms
id: SYMP:0000729

Axiom
annotated source: pulmonary consolidation
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a region of normally compressible lung tissue that has filled with liquid instead of air.
database_cross_reference: url:https://en.wikipedia.org/wiki/Pulmonary_consolidation

rapid respiration
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by an increased breathing rate, with more than 20 breaths per minute in an adult, while in children, the number of breaths per minute can be a higher resting rate than seen in adults.
has_obo_namespace: symptoms
id: SYMP:0000730

Axiom
annotated source: rapid respiration
annotated property: definition
annotated target: A respiratory abnormality that is characterized by an increased breathing rate, with more than 20 breaths per minute in an adult, while in children, the number of breaths per minute can be a higher resting rate than seen in adults.
database_cross_reference: url:https://www.healthline.com/health/rapid-shallow-breathing#What-is-tachypnea?

renal failure
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by a loss of excretory function in one or both kidneys, leading to retention of nitrogenous waste products from the blood.
has_obo_namespace: symptoms
id: SYMP:0000731

Axiom
annotated source: renal failure
annotated property: definition
annotated target: A urinary system symptom that is characterized by a loss of excretory function in one or both kidneys, leading to retention of nitrogenous waste products from the blood.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK519012/

sudden ataxis
type: Class
subclass of: ataxia
has_obo_namespace: symptoms
id: SYMP:0000732

sternocleidomastoid weakness
type: Class
subclass of: muscle weakness
has_obo_namespace: symptoms
id: SYMP:0000733

obsolete stroke
type: Class
definition: A nervous system symptom that is characterized by a sudden diminution or loss of consciousness, sensation, and voluntary motion caused by rupture or obstruction (as by a clot) of a blood vessel of the brain.
term replaced by: cerebrovascular accident
has_exact_synonym: apoplexy
has_exact_synonym: brain attack
has_exact_synonym: cerebral accident
has_exact_synonym: cerebrovascular accident
has_obo_namespace: symptoms
id: SYMP:0000734
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete stroke
annotated property: definition
annotated target: A nervous system symptom that is characterized by a sudden diminution or loss of consciousness, sensation, and voluntary motion caused by rupture or obstruction (as by a clot) of a blood vessel of the brain.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stroke

obsolete suppurative pneumonia
type: Class
definition: A pneumonia that is characterized by the formation of pus and destruction of pulmonary tissue; abscess formation may occur.
term replaced by: suppurative bronchiole inflammation
has_obo_namespace: symptoms
id: SYMP:0000735
comment: reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete suppurative pneumonia
annotated property: definition
annotated target: A pneumonia that is characterized by the formation of pus and destruction of pulmonary tissue; abscess formation may occur.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/suppurative+pneumonia

lymph gland swelling
type: Class
subclass of: swelling symptom
has_obo_namespace: symptoms
id: SYMP:0000736

respiratory tract mucosa ulcer
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an ulceration (dying and sloughing) of the bronchial or bronchiolar epithelium, exposing the underlying basement membrane.
has_obo_namespace: symptoms
id: SYMP:0000737

Axiom
annotated source: respiratory tract mucosa ulcer
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an ulceration (dying and sloughing) of the bronchial or bronchiolar epithelium, exposing the underlying basement membrane.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/respiratory+mucosa
database_cross_reference: url:https://ntp.niehs.nih.gov/nnl/respiratory/lung/ulcer/index.htm

yellowish green diarrhea
type: Class
subclass of: diarrhea
has_obo_namespace: symptoms
id: SYMP:0000738

bronchopulmonary bleeding
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by bleeding (hemorrhage) in either or both the bronchi and the lungs.
has_obo_namespace: symptoms
id: SYMP:0000739

Axiom
annotated source: bronchopulmonary bleeding
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by bleeding (hemorrhage) in either or both the bronchi and the lungs.
database_cross_reference: url:https://www.merriam-webster.com/medical/bronchopulmonary

genitourinary hemorrhage
type: Class
subclass of: urinary system symptom
has_obo_namespace: symptoms
id: SYMP:0000740

nasal bleeding
type: Class
subclass of: nose symptom
has_obo_namespace: symptoms
id: SYMP:0000741

gum bleeding
type: Class
subclass of: mouth bleeding
definition: Gum bleeding is a mouth symptom characterized by a copious discharge of blood from the blood vessels of the mucosal tissue that lies over the alveolar bone.
has_exact_synonym: gingival hemorrhage
has_obo_namespace: symptoms
id: SYMP:0000742

Axiom
annotated source: gum bleeding
annotated property: definition
annotated target: Gum bleeding is a mouth symptom characterized by a copious discharge of blood from the blood vessels of the mucosal tissue that lies over the alveolar bone.
database_cross_reference: url:http://en.wikipedia.org/wiki/Gingival
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hemorrhage

blotchy red rash
type: Class
subclass of: rash
has_obo_namespace: symptoms
id: SYMP:0000743

cervical lymphadenopathy
type: Class
subclass of: lymphadenopathy
has_obo_namespace: symptoms
id: SYMP:0000744

change in body sensation
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000745

enanthem
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an eruption on a mucous surface.
has_obo_namespace: symptoms
id: SYMP:0000746

Axiom
annotated source: enanthem
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an eruption on a mucous surface.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=enanthem

extreme prostration
type: Class
subclass of: prostration
has_obo_namespace: symptoms
id: SYMP:0000747

facial edema
type: Class
subclass of: edema
definition: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the face.
has_exact_synonym: facial swelling
has_obo_namespace: symptoms
id: SYMP:0000748

Axiom
annotated source: facial edema
annotated property: definition
annotated target: An adema that is characterized by an abnormal excess accumulation of serous fluid in connective tissue of the face.
database_cross_reference: url:https://angletoner.com/facial-swelling/

hemodynamic instability
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0000749

hemorrhage into mucous membrane
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000750

hemorrhage into skin
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0000751

herpetic lesion on upper lip
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000752

intense anxiety
type: Class
subclass of: anxiety
has_obo_namespace: symptoms
id: SYMP:0000753

severe chest pain
type: Class
subclass of: chest pain
has_exact_synonym: intense chest pain
has_obo_namespace: symptoms
id: SYMP:0000754

intense toxemia
type: Class
subclass of: toxemia
has_obo_namespace: symptoms
id: SYMP:0000755

menorrhagia
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized an abnormally profuse menstrual flow.
has_obo_namespace: symptoms
id: SYMP:0000756

Axiom
annotated source: menorrhagia
annotated property: definition
annotated target: A reproductive system symptom that is characterized an abnormally profuse menstrual flow.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=menorrhagia

mild conjunctivitis
type: Class
subclass of: conjunctivitis
has_obo_namespace: symptoms
id: SYMP:0000757

neurological alteration
type: Class
subclass of: nervous system symptom
has_obo_namespace: symptoms
id: SYMP:0000758

parotid pain
type: Class
subclass of: pain
definition: A pain that is characterized by a pain situated, or occurring, in the parotid gland, which is a salivary gland located in front of the ears. (Additional salivary glands include the submandibular and sublingual glands.) Pain is attributed to swelling of the gland.
has_exact_synonym: salivary gland pain
has_obo_namespace: symptoms
id: SYMP:0000759

Axiom
annotated source: parotid pain
annotated property: definition
annotated target: A pain that is characterized by a pain situated, or occurring, in the parotid gland, which is a salivary gland located in front of the ears. (Additional salivary glands include the submandibular and sublingual glands.) Pain is attributed to swelling of the gland.
database_cross_reference: url:https://en.wikipedia.org/wiki/Parotid_gland
database_cross_reference: url:https://en.wikipedia.org/wiki/Salivary_gland
database_cross_reference: url:https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=zp4169

petechiae
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a minute reddish or purplish spot containing blood that appears in skin or mucous membrane as a result of localized hemorrhage.
has_exact_synonym: petechial rash
has_obo_namespace: symptoms
id: SYMP:0000760

Axiom
annotated source: petechiae
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a minute reddish or purplish spot containing blood that appears in skin or mucous membrane as a result of localized hemorrhage.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=petechiae

extracellular fluid alteration
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000761

excess lymphocytes in cerebrospinal fluid
type: Class
subclass of: extracellular fluid alteration
has_obo_namespace: symptoms
id: SYMP:0000762

renal alteration
type: Class
subclass of: urinary system symptom
has_obo_namespace: symptoms
id: SYMP:0000763

retrobulbar pain
type: Class
subclass of: pain
definition: A pain that is characterized by a pain situated, or occurring, behind the eyeball.
has_obo_namespace: symptoms
id: SYMP:0000764

Axiom
annotated source: retrobulbar pain
annotated property: definition
annotated target: A pain that is characterized by a pain situated, or occurring, behind the eyeball.
database_cross_reference: url:https://www.merriam-webster.com/medical/retrobulbar

sensory disturbance
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000765

slow pulse
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0000766

subconjunctival bleeding
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0000767

testicular pain
type: Class
subclass of: pain
definition: A pain that is characterized by a pain in, or about, a testis (testicle) or testes. Testicular pain can be caused by nerve damage, sexually transmitted infections, gangrene, swelling, hernia, kidney stones, inflammation, enlarged veins, fluid in the testicle, or a severe condition known as testicular torsion.
has_obo_namespace: symptoms
id: SYMP:0000768

Axiom
annotated source: testicular pain
annotated property: definition
annotated target: A pain that is characterized by a pain in, or about, a testis (testicle) or testes. Testicular pain can be caused by nerve damage, sexually transmitted infections, gangrene, swelling, hernia, kidney stones, inflammation, enlarged veins, fluid in the testicle, or a severe condition known as testicular torsion.
database_cross_reference: url:https://www.healthline.com/health/testicle-pain

vascular alteration
type: Class
subclass of: cardiovascular system symptom
has_obo_namespace: symptoms
id: SYMP:0000769

pelvic symptom
type: Class
subclass of: abdominal symptom
has_obo_namespace: symptoms
id: SYMP:0000770

pelvic swelling
type: Class
subclass of: pelvic symptom
database_cross_reference: ICD9CM_2005:789.3
has_obo_namespace: symptoms
id: SYMP:0000771

pelvic mass
type: Class
subclass of: pelvic symptom
database_cross_reference: ICD9CM_2005:789.3
has_obo_namespace: symptoms
id: SYMP:0000772

pelvic lump
type: Class
subclass of: pelvic symptom
database_cross_reference: ICD9CM_2005:789.3
has_obo_namespace: symptoms
id: SYMP:0000773

generalized pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000774

right lower quadrant pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000775

epigastric pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000776

left lower quadrant pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000777

left upper quadrant pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000778

right upper quadrant pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000779

multiple sites pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000780

periumbilic pelvic lump
type: Class
subclass of: pelvic lump
has_obo_namespace: symptoms
id: SYMP:0000781

right upper quadrant pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000782

left lower quadrant pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000783

epigastric pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000784

left upper quadrant pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000785

generalized pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000786

periumbilic pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000787

multiple sites pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000788

right lower quadrant pelvic mass
type: Class
subclass of: pelvic mass
has_obo_namespace: symptoms
id: SYMP:0000789

multiple sites pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000790

generalized pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000791

epigastric pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000792

left lower quadrant pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000793

left upper quadrant pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000794

periumbilic pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000795

right lower quadrant pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000796

right upper quadrant pelvic swelling
type: Class
subclass of: pelvic swelling
has_obo_namespace: symptoms
id: SYMP:0000797

abdominal mass
type: Class
subclass of: abdominal symptom
database_cross_reference: ICD9CM_2005:789.3
database_cross_reference: UMLS_CUI:C0476310
has_obo_namespace: symptoms
id: SYMP:0000798

abdominal lump
type: Class
subclass of: abdominal symptom
has_obo_namespace: symptoms
id: SYMP:0000799

left upper quadrant abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000800

left lower quadrant abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000801

epigastric abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000802

multiple sites abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000803

generalized abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000804

periumbilic abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000805

right lower quadrant abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000806

right upper quadrant abdominal mass
type: Class
subclass of: abdominal mass
has_obo_namespace: symptoms
id: SYMP:0000807

multiple sites abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000808

periumbilic abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000809

epigastric abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000810

left upper quadrant abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000811

right lower quadrant abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000812

right upper quadrant abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000813

generalized abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000814

left lower quadrant abdominal lump
type: Class
subclass of: abdominal lump
has_obo_namespace: symptoms
id: SYMP:0000815

dysfunctions associated with arousal from sleep
type: Class
subclass of: sleep disturbance
database_cross_reference: ICD9CM_2005:307.47
has_obo_namespace: symptoms
id: SYMP:0000816

inability to concentrate
type: Class
subclass of: alteration of consciousness
has_obo_namespace: symptoms
id: SYMP:0000817

localized superficial mass
type: Class
subclass of: skin and integumentary tissue symptom
database_cross_reference: ICD9CM_2005:782.2
has_obo_namespace: symptoms
id: SYMP:0000818

localized superficial swelling
type: Class
subclass of: skin and integumentary tissue symptom
database_cross_reference: ICD9CM_2005:782.2
has_obo_namespace: symptoms
id: SYMP:0000819

mass in chest
type: Class
subclass of: respiratory system and chest symptom
database_cross_reference: ICD9CM_2005:786.6
has_obo_namespace: symptoms
id: SYMP:0000820

swelling in chest
type: Class
subclass of: respiratory system and chest symptom
has_obo_namespace: symptoms
id: SYMP:0000821

chronic enteritis
type: Class
subclass of: enteritis
definition: Chronic enteritis is a enteritis with slow progress, long duration, or frequent recurrence which can be due to Crohn's disease, giardiasis, tuberculosis, coeliac disease, or rarely due to Whipple's disease.
has_obo_namespace: symptoms
id: SYMP:0000822

Axiom
annotated source: chronic enteritis
annotated property: definition
annotated target: Chronic enteritis is a enteritis with slow progress, long duration, or frequent recurrence which can be due to Crohn's disease, giardiasis, tuberculosis, coeliac disease, or rarely due to Whipple's disease.
database_cross_reference: url:http://en.wikipedia.org/wiki/Enteritis
database_cross_reference: url:http://www.rootsweb.ancestry.com/~vapage2/deathcauses.htm

sinus bradycardia
type: Class
subclass of: bradycardia
definition: Sinus bradycardia is a bradycardia where the sinus rhythm is abnormally slow bradycardia consisting of a sinus rhythm at a rate lower than 60 beats per minute.
has_obo_namespace: symptoms
id: SYMP:0000823

Axiom
annotated source: sinus bradycardia
annotated property: definition
annotated target: Sinus bradycardia is a bradycardia where the sinus rhythm is abnormally slow bradycardia consisting of a sinus rhythm at a rate lower than 60 beats per minute.

junctional tachycardia
type: Class
subclass of: tachycardia
definition: Junctional tachycardia is a tachycardia associated with the generation of impulses in a locus in the region of the atrioventricular node.
has_obo_namespace: symptoms
id: SYMP:0000824

Axiom
annotated source: junctional tachycardia
annotated property: definition
annotated target: Junctional tachycardia is a tachycardia associated with the generation of impulses in a locus in the region of the atrioventricular node.

paroxysmal tachycardia
type: Class
subclass of: tachycardia
definition: Paroxysmal tachycardia is a tachycardia that begins and ends abruptly and that is initiated by a premature supraventricular beat originating in the atrium or in the atrioventricular node or bundle of His or by a premature ventricular beat.
has_obo_namespace: symptoms
id: SYMP:0000825

Axiom
annotated source: paroxysmal tachycardia
annotated property: definition
annotated target: Paroxysmal tachycardia is a tachycardia that begins and ends abruptly and that is initiated by a premature supraventricular beat originating in the atrium or in the atrioventricular node or bundle of His or by a premature ventricular beat.

sinus tachycardia
type: Class
subclass of: tachycardia
definition: Sinus tachycardia is a tachychardia characterized by an abnormally rapid sinus rhythm specifically a sinus rhythm at a rate greater than 100 beats per minute.
has_obo_namespace: symptoms
id: SYMP:0000826

Axiom
annotated source: sinus tachycardia
annotated property: definition
annotated target: Sinus tachycardia is a tachychardia characterized by an abnormally rapid sinus rhythm specifically a sinus rhythm at a rate greater than 100 beats per minute.

ventricular tachycardia
type: Class
subclass of: tachycardia
definition: A tachycardia that is associated with the generation of improper electrical impulses within the ventricles, characterized by an electrocardiogram showing a rate of greater than 120 BPM and three or more wide QRS complexes in a row.
has_exact_synonym: V-tach
has_exact_synonym: VT
has_obo_namespace: symptoms
id: SYMP:0000827

Axiom
annotated source: ventricular tachycardia
annotated property: definition
annotated target: A tachycardia that is associated with the generation of improper electrical impulses within the ventricles, characterized by an electrocardiogram showing a rate of greater than 120 BPM and three or more wide QRS complexes in a row.
database_cross_reference: url:https://en.wikipedia.org/wiki/Ventricular_tachycardia

sore eyes
type: Class
subclass of: eye symptom
definition: Sore eyes is a eye symptom characterized by an inflammation of the thin covering of the eyeball and the inner eyelid brought about by a viral infection which may be highly contagious.
has_obo_namespace: symptoms
id: SYMP:0000828

Axiom
annotated source: sore eyes
annotated property: definition
annotated target: Sore eyes is a eye symptom characterized by an inflammation of the thin covering of the eyeball and the inner eyelid brought about by a viral infection which may be highly contagious.
database_cross_reference: url:http://www.doh.gov.ph/faqs/sore_eyes

neck pain
type: Class
subclass of: pain
definition: A pain that is characterized by an unpleasant sensation localized in the neck that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual.
has_obo_namespace: symptoms
id: SYMP:0000829

Axiom
annotated source: neck pain
annotated property: definition
annotated target: A pain that is characterized by an unpleasant sensation localized in the neck that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

phantom pain
type: Class
subclass of: pain
definition: A pain that is characterized by a painful sensation that is perceived to originate in the amputated portion of the extremety. Patients may have localized pain that originates in the stump.
has_obo_namespace: symptoms
id: SYMP:0000830

Axiom
annotated source: phantom pain
annotated property: definition
annotated target: A pain that is characterized by a painful sensation that is perceived to originate in the amputated portion of the extremety. Patients may have localized pain that originates in the stump.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

nociceptive pain
type: Class
subclass of: pain
definition: A pain that is characterized by originating from other than the peripheral and central nervous systems, and which is caused by activation of nociceptive fibers.
has_obo_namespace: symptoms
id: SYMP:0000831

Axiom
annotated source: nociceptive pain
annotated property: definition
annotated target: A pain that is characterized by originating from other than the peripheral and central nervous systems, and which is caused by activation of nociceptive fibers.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

neuropathic pain
type: Class
subclass of: pain
definition: A pain that is characterized by being experienced by cancer patients and which is caused by radiotherapy or chemotherapy damage to nerves, when cancer invades or compresses nerves, or when, during cancer treatment. This type of pain is typically described as burning, electrical, or strange feeling.
has_obo_namespace: symptoms
id: SYMP:0000832

Axiom
annotated source: neuropathic pain
annotated property: definition
annotated target: A pain that is characterized by being experienced by cancer patients and which is caused by radiotherapy or chemotherapy damage to nerves, when cancer invades or compresses nerves, or when, during cancer treatment. This type of pain is typically described as burning, electrical, or strange feeling.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

visceral pain
type: Class
subclass of: pain
definition: A pain that is characterized by originating from organ tissues of the thorax, abdomen, or pelvis. It characterizes as deep, vague, and difficult to locate pain, that radiates away from the affected organ.
has_obo_namespace: symptoms
id: SYMP:0000833

Axiom
annotated source: visceral pain
annotated property: definition
annotated target: A pain that is characterized by originating from organ tissues of the thorax, abdomen, or pelvis. It characterizes as deep, vague, and difficult to locate pain, that radiates away from the affected organ.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

hypoesthesia
type: Class
subclass of: sensation perception
definition: A sensation perception that is characterized by a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli.
has_exact_synonym: numbness
has_obo_namespace: symptoms
id: SYMP:0000834

Axiom
annotated source: hypoesthesia
annotated property: definition
annotated target: A sensation perception that is characterized by a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli.
database_cross_reference: url:https://en.wikipedia.org/wiki/Hypoesthesia

hypoalgesia
type: Class
subclass of: sensation perception
definition: A sensation perception that is characterized by a diminished sensitivity to painful stimulation.
has_obo_namespace: symptoms
id: SYMP:0000835

Axiom
annotated source: hypoalgesia
annotated property: definition
annotated target: A sensation perception that is characterized by a diminished sensitivity to painful stimulation.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

hyperalgesia
type: Class
subclass of: sensation perception
definition: A sensation perception that is characterized by an increased response to a painful stimulus.
has_obo_namespace: symptoms
id: SYMP:0000836

Axiom
annotated source: hyperalgesia
annotated property: definition
annotated target: A sensation perception that is characterized by an increased response to a painful stimulus.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

chronic pain
type: Class
subclass of: pain
definition: A pain that is characterized by ranging from mild to severe and which continues beyond the expected healing phase.
has_obo_namespace: symptoms
id: SYMP:0000837

Axiom
annotated source: chronic pain
annotated property: definition
annotated target: A pain that is characterized by ranging from mild to severe and which continues beyond the expected healing phase.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

breakthrough pain
type: Class
subclass of: pain
definition: A pain that is characterized by occurring with movement and is not controlled by a scheduled pain medication regimen, such that the pain breaks through the current regimen. This is usually referred to in the context of a short and long acting opioid, the short acting opioid being used to treat the breakthrough pain.
has_obo_namespace: symptoms
id: SYMP:0000838

Axiom
annotated source: breakthrough pain
annotated property: definition
annotated target: A pain that is characterized by occurring with movement and is not controlled by a scheduled pain medication regimen, such that the pain breaks through the current regimen. This is usually referred to in the context of a short and long acting opioid, the short acting opioid being used to treat the breakthrough pain.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

acute pain
type: Class
subclass of: pain
definition: A pain that is characterized by being severe but lasting a relatively short time.
has_exact_synonym: sudden pain
has_obo_namespace: symptoms
id: SYMP:0000839

Axiom
annotated source: acute pain
annotated property: definition
annotated target: A pain that is characterized by being severe but lasting a relatively short time.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

allodynia
type: Class
subclass of: pain
definition: A pain that is characterized by a painful sensation with a normal, non-painful stimulation.
has_obo_namespace: symptoms
id: SYMP:0000840

Axiom
annotated source: allodynia
annotated property: definition
annotated target: A pain that is characterized by a painful sensation with a normal, non-painful stimulation.
database_cross_reference: url:http://www.nationalpainfoundation.org/MyTreatment/articles/Cancer_PainDefinitions.asp

reactive hyperemia
type: Class
subclass of: hyperemia
definition: Reactive hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to a profound increase in blood flow to an organ after being occluded. There will be a shortage of oxygen and a build-up of metabolic waste.
has_obo_namespace: symptoms
id: SYMP:0000841

Axiom
annotated source: reactive hyperemia
annotated property: definition
annotated target: Reactive hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to a profound increase in blood flow to an organ after being occluded. There will be a shortage of oxygen and a build-up of metabolic waste.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

active hyperemia
type: Class
subclass of: hyperemia
definition: Active hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to an increase in metabolism.
has_obo_namespace: symptoms
id: SYMP:0000842

Axiom
annotated source: active hyperemia
annotated property: definition
annotated target: Active hyperemia is a hyperemia occuring due to the dilation of arteriolar smooth muscle to increase blood flow in response to an increase in metabolism.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

functional hyperemia
type: Class
subclass of: hyperemia
definition: Functional hyperemia is a hyperemia occuring due to an increase in blood flow to a tissue due to the presence of metabolites and a change in general conditions.
has_obo_namespace: symptoms
id: SYMP:0000843

Axiom
annotated source: functional hyperemia
annotated property: definition
annotated target: Functional hyperemia is a hyperemia occuring due to an increase in blood flow to a tissue due to the presence of metabolites and a change in general conditions.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

face hyperemia
type: Class
subclass of: head symptom
definition: Hyperemia of the face is a head symptom consisting of an excess of blood in the tissues of the face as from an increased flow of blood due to vasodilation.
has_obo_namespace: symptoms
id: SYMP:0000844

Axiom
annotated source: face hyperemia
annotated property: definition
annotated target: Hyperemia of the face is a head symptom consisting of an excess of blood in the tissues of the face as from an increased flow of blood due to vasodilation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

hyperemia of the neck
type: Class
subclass of: neck symptom
definition: Hyperemia of the neck is a neck symptom consisting of an excess of blood in the tissues of the neck as from an increased flow of blood due to vasodilation.
has_obo_namespace: symptoms
id: SYMP:0000845

Axiom
annotated source: hyperemia of the neck
annotated property: definition
annotated target: Hyperemia of the neck is a neck symptom consisting of an excess of blood in the tissues of the neck as from an increased flow of blood due to vasodilation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

chest hyperemia
type: Class
subclass of: cardiovascular system symptom
definition: Hyperemia of the chest is a cardiovascular system symptom consisting of an excess of blood in the tissues of the chest as from an increased flow of blood due to vasodilation.
has_obo_namespace: symptoms
id: SYMP:0000846

Axiom
annotated source: chest hyperemia
annotated property: definition
annotated target: Hyperemia of the chest is a cardiovascular system symptom consisting of an excess of blood in the tissues of the chest as from an increased flow of blood due to vasodilation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hyperemia

spastic paralysis
type: Class
subclass of: paralysis
definition: A paralysis that is characterized by a tonic spasm of the affected muscles and with increased tendon reflexes.
has_obo_namespace: symptoms
id: SYMP:0000847

Axiom
annotated source: spastic paralysis
annotated property: definition
annotated target: A paralysis that is characterized by a tonic spasm of the affected muscles and with increased tendon reflexes.

motor paralysis
type: Class
subclass of: paralysis
definition: A paralysis that is characterized by a complete or partial loss of function the voluntary muscles.
has_obo_namespace: symptoms
id: SYMP:0000848

Axiom
annotated source: motor paralysis
annotated property: definition
annotated target: A paralysis that is characterized by a complete or partial loss of function the voluntary muscles.

stillbirth
type: Class
subclass of: reproductive system symptom
definition: A reproductive system symptom that is characterized by the birth of a dead fetus; in which a fetus that has died in the uterus, or during labor, or delivery, exits a woman's body.
has_obo_namespace: symptoms
id: SYMP:0000849

Axiom
annotated source: stillbirth
annotated property: definition
annotated target: A reproductive system symptom that is characterized by the birth of a dead fetus; in which a fetus that has died in the uterus, or during labor, or delivery, exits a woman's body.
database_cross_reference: url:http://en.wikipedia.org/wiki/Still_birth
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=stillbirth

congested sclera
type: Class
subclass of: hyperemia
definition: Congested sclera is a hyperemia characterized as the congestion of the vessels of the outer layer of the eye containing collagen and elastic fibers.
has_obo_namespace: symptoms
id: SYMP:0000850

Axiom
annotated source: congested sclera
annotated property: definition
annotated target: Congested sclera is a hyperemia characterized as the congestion of the vessels of the outer layer of the eye containing collagen and elastic fibers.
database_cross_reference: url:http://en.wikipedia.org/wiki/Sclera

gross hematuria
type: Class
subclass of: hematuria
definition: A hematuria that is characterized by the production of a visible redness in the urine.
has_obo_namespace: symptoms
id: SYMP:0000851

Axiom
annotated source: gross hematuria
annotated property: definition
annotated target: A hematuria that is characterized by the production of a visible redness in the urine.

anuria
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by the absence of, or by defective, urine excretion.
database_cross_reference: ICD9CM_2005:788.5
database_cross_reference: UMLS_CUI:C0028962
database_cross_reference: UMLS_ICD9CM_2005_AUI:A0243854
has_obo_namespace: symptoms
id: SYMP:0000852
comment: doid/symp duplicate

Axiom
annotated source: anuria
annotated property: definition
annotated target: A urinary system symptom that is characterized by the absence of, or by defective, urine excretion.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=anuria

stress incontinence
type: Class
subclass of: urinary incontinence
definition: A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder accompanying physical activity (as in laughing, coughing, sneezing, or physical exercise) which places increased pressure on the abdomen.
has_obo_namespace: symptoms
id: SYMP:0000853

Axiom
annotated source: stress incontinence
annotated property: definition
annotated target: A urinary incontinence that is characterized by an involuntary leakage of urine from the bladder accompanying physical activity (as in laughing, coughing, sneezing, or physical exercise) which places increased pressure on the abdomen.
database_cross_reference: url:https://www.health.harvard.edu/bladder-and-bowel/types-of-urinary-incontinence

hypermenorrhea
type: Class
subclass of: menorrhagia
definition: A menorrhagia that is characterized by an abnormally profuse or prolonged menstrual flow.
has_obo_namespace: symptoms
id: SYMP:0000854

Axiom
annotated source: hypermenorrhea
annotated property: definition
annotated target: A menorrhagia that is characterized by an abnormally profuse or prolonged menstrual flow.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hypermenorrhea

metrorrhagia
type: Class
subclass of: menorrhagia
definition: A menorrhagia that is characterized by an irregular uterine bleeding, especially between menstrual periods.
has_obo_namespace: symptoms
id: SYMP:0000855

Axiom
annotated source: metrorrhagia
annotated property: definition
annotated target: A menorrhagia that is characterized by an irregular uterine bleeding, especially between menstrual periods.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=metrorrhagia

subjective vertigo
type: Class
subclass of: vertigo
definition: A vertigo that is characterized by a sensation that one's body is revolving in space.
has_obo_namespace: symptoms
id: SYMP:0000856

Axiom
annotated source: subjective vertigo
annotated property: definition
annotated target: A vertigo that is characterized by a sensation that one's body is revolving in space.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=subjective+vertigo

objective vertigo
type: Class
subclass of: vertigo
definition: A vertigo that is characterized by a sensation that the external world is revolving.
has_obo_namespace: symptoms
id: SYMP:0000857

Axiom
annotated source: objective vertigo
annotated property: definition
annotated target: A vertigo that is characterized by a sensation that the external world is revolving.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=objective+vertigo

hypokinesia
type: Class
subclass of: musculoskeletal system symptom
definition: Hypokinesia is a musculoskeletal system symptom characterized by the slow or diminished movement of body musculature. It may be associated with basal ganglia diseases; mental disorders; prolonged inactivity due to illness; experimental protocols used to evaluate the physiologic effects of immobility; and other conditions.
has_obo_namespace: symptoms
id: SYMP:0000858

Axiom
annotated source: hypokinesia
annotated property: definition
annotated target: Hypokinesia is a musculoskeletal system symptom characterized by the slow or diminished movement of body musculature. It may be associated with basal ganglia diseases; mental disorders; prolonged inactivity due to illness; experimental protocols used to evaluate the physiologic effects of immobility; and other conditions.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hypokinesia

rigidity hypokinesia
type: Class
subclass of: hypokinesia
definition: Rigidity hypokinesia a type of hypokinesia described as the increase in muscle tension when moved by an outside force.
has_obo_namespace: symptoms
id: SYMP:0000859

Axiom
annotated source: rigidity hypokinesia
annotated property: definition
annotated target: Rigidity hypokinesia a type of hypokinesia described as the increase in muscle tension when moved by an outside force.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hypokinesia

postural instability hypokinesia
type: Class
subclass of: hypokinesia
definition: Postural instability hypokinesia is a hypokinesia described as a loss of ability to maintain an upright posture.
has_obo_namespace: symptoms
id: SYMP:0000860

Axiom
annotated source: postural instability hypokinesia
annotated property: definition
annotated target: Postural instability hypokinesia is a hypokinesia described as a loss of ability to maintain an upright posture.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hypokinesia

freezing hypokinesia
type: Class
subclass of: hypokinesia
definition: Freezing hypokinesia is a hypkinesia where a person can not move their muscles how they want them to.
has_obo_namespace: symptoms
id: SYMP:0000861

Axiom
annotated source: freezing hypokinesia
annotated property: definition
annotated target: Freezing hypokinesia is a hypkinesia where a person can not move their muscles how they want them to.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hypokinesia

referred pain
type: Class
subclass of: pain
definition: A pain that is characterized by pain which is subjectively localized in one region although it is due to irritation in another region.
has_obo_namespace: symptoms
id: SYMP:0000862

Axiom
annotated source: referred pain
annotated property: definition
annotated target: A pain that is characterized by pain which is subjectively localized in one region although it is due to irritation in another region.

facial tremor
type: Class
subclass of: head symptom
definition: Facial tremor is a head symptom characterized by a trembling or shaking of the muscles of the face usually from physical weakness, emotional stress, or disease, may be emphasized by the firm closure of the eyes, elevation of the eyebrows, or drawing down and outward of the corners of the mouth.
has_obo_namespace: symptoms
id: SYMP:0000863

Axiom
annotated source: facial tremor
annotated property: definition
annotated target: Facial tremor is a head symptom characterized by a trembling or shaking of the muscles of the face usually from physical weakness, emotional stress, or disease, may be emphasized by the firm closure of the eyes, elevation of the eyebrows, or drawing down and outward of the corners of the mouth.
database_cross_reference: url:http://www.merriam-webster.com/dictionary/tremors

lesions in oropharynx
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0000864

lesions in mouth
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000865

cervical edema
type: Class
subclass of: neck symptom
definition: Cervical edema is a neck symptom characterized by an abnormal excess accumulation of serous fluid in the soft tissue of the cervical area.
has_obo_namespace: symptoms
id: SYMP:0000866

Axiom
annotated source: cervical edema
annotated property: definition
annotated target: Cervical edema is a neck symptom characterized by an abnormal excess accumulation of serous fluid in the soft tissue of the cervical area.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=edema

gastrointestinal bleeding
type: Class
subclass of: digestive system symptom
definition: A digestive system symptom characterized by bleeding from one or more of the areas of the digestive or gastrointestinal (GI) tract that includes the espophagus, stomach, small intestine, large intestine or colon, rectum and anus.
has_obo_namespace: symptoms
id: SYMP:0000867

Axiom
annotated source: gastrointestinal bleeding
annotated property: definition
annotated target: A digestive system symptom characterized by bleeding from one or more of the areas of the digestive or gastrointestinal (GI) tract that includes the espophagus, stomach, small intestine, large intestine or colon, rectum and anus.
database_cross_reference: url:http://www.nlm.nih.gov/medlineplus/gastrointestinalbleeding.html

breathing problems
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by a shortness of breath, a hard or uncomfortable intake of air, or the feeling that you're not getting enough air.
has_obo_namespace: symptoms
id: SYMP:0000868

Axiom
annotated source: breathing problems
annotated property: definition
annotated target: A respiratory abnormality that is characterized by a shortness of breath, a hard or uncomfortable intake of air, or the feeling that you're not getting enough air.
database_cross_reference: url:http://www.nlm.nih.gov/medlineplus/breathingproblems.html

nasal congestion
type: Class
subclass of: congestion
definition: A congestion that is characterized by a blockage of the nasal passages, usually due to the membranes lining the nose becoming swollen from inflamed blood vessels.
has_obo_namespace: symptoms
id: SYMP:0000869

Axiom
annotated source: nasal congestion
annotated property: definition
annotated target: A congestion that is characterized by a blockage of the nasal passages, usually due to the membranes lining the nose becoming swollen from inflamed blood vessels.
database_cross_reference: url:http://en.wikipedia.org/wiki/Nasal_congestion

icteric eyes
type: Class
subclass of: eye symptom
definition: Icteric eyes is a eye symptom characterized by yellowed eyes due to bile or bilirubin accumulation.
has_obo_namespace: symptoms
id: SYMP:0000870

Axiom
annotated source: icteric eyes
annotated property: definition
annotated target: Icteric eyes is a eye symptom characterized by yellowed eyes due to bile or bilirubin accumulation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Jaundice
database_cross_reference: url:http://www3.niaid.nih.gov/labs/aboutlabs/cmb/InfectiousDiseasePathogenesisSection/mouseNecropsy/necropsyTerms.htm

icteric mucous membrane
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by yellowed mucous membranes due to bile or bilirubin accumulation.
has_obo_namespace: symptoms
id: SYMP:0000871

Axiom
annotated source: icteric mucous membrane
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by yellowed mucous membranes due to bile or bilirubin accumulation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Jaundice

icteric skin
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by yellowed skin due to bile or bilirubin accumulation.
has_obo_namespace: symptoms
id: SYMP:0000872

Axiom
annotated source: icteric skin
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by yellowed skin due to bile or bilirubin accumulation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Jaundice

otitis
type: Class
subclass of: ear symptom
definition: Otitis is a ear symptom characterized as a general term for inflammation or infection of the ear, in both humans and other animals.
has_obo_namespace: symptoms
id: SYMP:0000873

Axiom
annotated source: otitis
annotated property: definition
annotated target: Otitis is a ear symptom characterized as a general term for inflammation or infection of the ear, in both humans and other animals.
database_cross_reference: url:http://en.wikipedia.org/wiki/Otitis

hematoma
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a mass of usually clotted blood that forms in a tissue, organ, or body space as a result of a broken blood vessel generally the result of hemorrhage, or more specifically, internal bleeding.
has_obo_namespace: symptoms
id: SYMP:0000874

Axiom
annotated source: hematoma
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a mass of usually clotted blood that forms in a tissue, organ, or body space as a result of a broken blood vessel generally the result of hemorrhage, or more specifically, internal bleeding.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hematoma
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=Hematomas

lameness
type: Class
subclass of: musculoskeletal system symptom
definition: Lameness is a musculoskeletal system symptom where a person is physically disabled as the result of having a body part and especially a limb so disabled as to impair freedom of movement.
has_obo_namespace: symptoms
id: SYMP:0000875

Axiom
annotated source: lameness
annotated property: definition
annotated target: Lameness is a musculoskeletal system symptom where a person is physically disabled as the result of having a body part and especially a limb so disabled as to impair freedom of movement.
database_cross_reference: url:http://www.merriam-webster.com/dictionary/lame

pericardial effusion
type: Class
subclass of: cardiovascular system symptom
definition: Pericardial effusion is a cardiovascular system symptom where there is an abnormal accumulation of fluid in the pericardial cavity.
has_obo_namespace: symptoms
id: SYMP:0000876
comment: doid/symp duplicate

Axiom
annotated source: pericardial effusion
annotated property: definition
annotated target: Pericardial effusion is a cardiovascular system symptom where there is an abnormal accumulation of fluid in the pericardial cavity.
database_cross_reference: url:http://en.wikipedia.org/wiki/Pericardial_effusion

decreased tongue tone
type: Class
subclass of: mouth symptom
has_obo_namespace: symptoms
id: SYMP:0000877

transient fever
type: Class
subclass of: fever
definition: A fever that is characterized by a rise of body temperature above the normal that is sustained for only a short period of time.
has_obo_namespace: symptoms
id: SYMP:0000878

Axiom
annotated source: transient fever
annotated property: definition
annotated target: A fever that is characterized by a rise of body temperature above the normal that is sustained for only a short period of time.
database_cross_reference: url:http://en.wiktionary.org/wiki/fever
database_cross_reference: url:http://en.wiktionary.org/wiki/transient

low-grade fever
type: Class
subclass of: mild fever
definition: A mild fever that is characterized by a fever that does not exceed 38.5 degrees Celsius (101.3 degrees Fahrenheit).
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_exact_synonym: low grade fever
has_obo_namespace: symptoms
id: SYMP:0000879

Axiom
annotated source: low-grade fever
annotated property: definition
annotated target: A mild fever that is characterized by a fever that does not exceed 38.5 degrees Celsius (101.3 degrees Fahrenheit).
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/low_grade_fever.htm

prolonged fever
type: Class
subclass of: fever
definition: A fever that is characterized by as persisting over a prolonged period of time.
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_obo_namespace: symptoms
id: SYMP:0000880

Axiom
annotated source: prolonged fever
annotated property: definition
annotated target: A fever that is characterized by as persisting over a prolonged period of time.
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/prolonged_fever.htm

mild fever
type: Class
subclass of: fever
definition: A fever that is characterized by being mild in form.
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_obo_namespace: symptoms
id: SYMP:0000881

Axiom
annotated source: mild fever
annotated property: definition
annotated target: A fever that is characterized by being mild in form.
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/mild_fever.htm

high fever
type: Class
subclass of: fever
definition: A fever that is characterized by an elevated temperature.
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_obo_namespace: symptoms
id: SYMP:0000882

Axiom
annotated source: high fever
annotated property: definition
annotated target: A fever that is characterized by an elevated temperature.
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/high_fever.htm

very high fever
type: Class
subclass of: high fever
definition: A high fever that is characterized by extremely high temperatures.
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_obo_namespace: symptoms
id: SYMP:0000883

Axiom
annotated source: very high fever
annotated property: definition
annotated target: A high fever that is characterized by extremely high temperatures.
database_cross_reference: url:http://www.wrongdiagnosis.com/sym/very_high_fever.htm

obsolete severe temperature increase
type: Class
created by: lschriml
creation date: 2010-10-15T11:28:26Z
has_obo_namespace: symptoms
id: SYMP:0000885
deprecated: true

hyperpyrexia
type: Class
subclass of: fever
definition: A fever that is characterized by an extreme elevation of body temperature greater than, or equal to, 41.5 degrees Celsius (106.7 degrees Fahrenheit).
created by: lschriml
creation date: 2010-10-15T11:38:55Z
has_obo_namespace: symptoms
id: SYMP:0000886

Axiom
annotated source: hyperpyrexia
annotated property: definition
annotated target: A fever that is characterized by an extreme elevation of body temperature greater than, or equal to, 41.5 degrees Celsius (106.7 degrees Fahrenheit).
database_cross_reference: url:http://en.wikipedia.org/wiki/Fever

Pel-Epstein fever
type: Class
subclass of: fever
definition: A fever that is characterized by association with Hodgkin's lymphoma, where the fever alternates weekly from high to low.
created by: lschriml
creation date: 2010-10-15T11:40:07Z
has_obo_namespace: symptoms
id: SYMP:0000887

Axiom
annotated source: Pel-Epstein fever
annotated property: definition
annotated target: A fever that is characterized by association with Hodgkin's lymphoma, where the fever alternates weekly from high to low.
database_cross_reference: url:http://en.wikipedia.org/wiki/Fever

continuous fever
type: Class
subclass of: fever
definition: A fever that is characterized by a temperature remaining above normal throughout the day and which does not fluctuate more than 1 degree Celsius in 24 hours.
created by: lschriml
creation date: 2010-10-15T11:42:19Z
has_obo_namespace: symptoms
has_related_synonym: continued fever
id: SYMP:0000888

Axiom
annotated source: continuous fever
annotated property: definition
annotated target: A fever that is characterized by a temperature remaining above normal throughout the day and which does not fluctuate more than 1 degree Celsius in 24 hours.
database_cross_reference: url:http://en.wikipedia.org/wiki/Fever#Types

remittent fever
type: Class
subclass of: fever
definition: A fever that is characterized by a fever where the temperature remains above normal throughout the day and fluctuates more than 1 degree Celsius in 24 hours.
created by: lschriml
creation date: 2010-10-15T11:42:19Z
has_obo_namespace: symptoms
id: SYMP:0000889

Axiom
annotated source: remittent fever
annotated property: definition
annotated target: A fever that is characterized by a fever where the temperature remains above normal throughout the day and fluctuates more than 1 degree Celsius in 24 hours.
database_cross_reference: url:http://en.wikipedia.org/wiki/Fever#Types

relapsing fever
type: Class
subclass of: fever
definition: A fever that is characterized by body temperature periodically rising and falling.
created by: lschriml
creation date: 2010-10-15T11:46:03Z
has_obo_namespace: symptoms
id: SYMP:0000890
comment: doid/symp duplicate

Axiom
annotated source: relapsing fever
annotated property: definition
annotated target: A fever that is characterized by body temperature periodically rising and falling.
database_cross_reference: url:https://www.merckmanuals.com/professional/infectious-diseases/spirochetes/relapsing-fever

musculoskeletal system symptom
type: Class
subclass of: symptom
created by: lschriml
creation date: 2010-10-15T11:48:05Z
has_obo_namespace: symptoms
id: SYMP:0000891

sensation perception
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by interpretation of the information perceived by sensory receptors.
created by: lschriml
creation date: 2010-10-15T11:54:30Z
has_obo_namespace: symptoms
id: SYMP:0000892

Axiom
annotated source: sensation perception
annotated property: definition
annotated target: A nervous system symptom that is characterized by interpretation of the information perceived by sensory receptors.
database_cross_reference: url:http://www.audiblox2000.com/sensation-perception.htm

hypotensive
type: Class
subclass of: low blood pressure
definition: A low blood pressure characterized by or due to abnormally low blood pressure, especially in the arteries of the systemic circulation.
created by: lschriml
creation date: 2011-11-17T12:20:22Z
has_obo_namespace: symptoms
id: SYMP:0000893

Axiom
annotated source: hypotensive
annotated property: definition
annotated target: A low blood pressure characterized by or due to abnormally low blood pressure, especially in the arteries of the systemic circulation.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hypotension
database_cross_reference: url:http://www.merriam-webster.com/medlineplus/hypotensive

cold clammy skin
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by cold, moist and sticky skin.
created by: lschriml
creation date: 2011-11-17T12:27:44Z
has_obo_namespace: symptoms
id: SYMP:0000894

Axiom
annotated source: cold clammy skin
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by cold, moist and sticky skin.
database_cross_reference: url:http://www.merriam-webster.com/medlineplus/clammy

anaphylactic shock
type: Class
subclass of: immune system symptom
definition: An acute allergic reaction to an antigen to which the body has become hypersensitive.
has_exact_synonym: anaphylaxis
has_obo_namespace: symptoms
id: SYMP:0000895

Axiom
annotated source: anaphylactic shock
annotated property: definition
annotated target: An acute allergic reaction to an antigen to which the body has become hypersensitive.
database_cross_reference: url:https://en.wikipedia.org/wiki/Anaphylaxis

exophthalmos
type: Class
subclass of: eye symptom
definition: An abnormal protrusion or displacement of an eye or other body part.
has_exact_synonym: exophthalmia
has_exact_synonym: exophthalmus
has_exact_synonym: proptosis
has_obo_namespace: symptoms
id: SYMP:0000896
comment: doid/symp duplicate

Axiom
annotated source: exophthalmos
annotated property: definition
annotated target: An abnormal protrusion or displacement of an eye or other body part.
database_cross_reference: url:https://en.wikipedia.org/wiki/Exophthalmos
database_cross_reference: url:https://www.merckmanuals.com/professional/eye-disorders/symptoms-of-ophthalmologic-disorders/proptosis
database_cross_reference: url:https://www.nhs.uk/conditions/bulging-eyes/

ventricular bradycardia
type: Class
subclass of: bradycardia
definition: A bradycardia associated with the generation of impules in the ventricles when impules from the atria fail to reach them, characterized by an electrocardiogram showing a heart rate below 50 BPM and a broad QRS complex.
has_exact_synonym: idioventricular rhythm
has_exact_synonym: ventricular escape rhythm
has_obo_namespace: symptoms
id: SYMP:0000897

Axiom
annotated source: ventricular bradycardia
annotated property: definition
annotated target: A bradycardia associated with the generation of impules in the ventricles when impules from the atria fail to reach them, characterized by an electrocardiogram showing a heart rate below 50 BPM and a broad QRS complex.
database_cross_reference: url:https://en.wikipedia.org/wiki/Ventricular_escape_beat

cardiac fibrillation
type: Class
subclass of: arrhythmia
definition: An arrhythmia characterized by rapid, irregular, and unsynchronized contraction of muscle fibers within the heart.
has_obo_namespace: symptoms
id: SYMP:0000898

Axiom
annotated source: cardiac fibrillation
annotated property: definition
annotated target: An arrhythmia characterized by rapid, irregular, and unsynchronized contraction of muscle fibers within the heart.
database_cross_reference: url:https://en.wikipedia.org/wiki/Fibrillation

ventricular fibrillation
type: Class
subclass of: cardiac fibrillation
definition: A cardiac fibrillation associated with quivering of the lower chambers of the heart, preventing blood from being pumped and causing cardiac arrest.
has_exact_synonym: v-fib
has_obo_namespace: symptoms
id: SYMP:0000899

Axiom
annotated source: ventricular fibrillation
annotated property: definition
annotated target: A cardiac fibrillation associated with quivering of the lower chambers of the heart, preventing blood from being pumped and causing cardiac arrest.
database_cross_reference: url:http://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/Ventricular-Fibrillation_UCM_324063_Article.jsp#.WvWbgFMvwnU

allergic reaction
type: Class
subclass of: immune system symptom
definition: An immune system symptom that is characterized by sensitivities to substances called allergens.
has_obo_namespace: symptoms
id: SYMP:0000900

Axiom
annotated source: allergic reaction
annotated property: definition
annotated target: An immune system symptom that is characterized by sensitivities to substances called allergens.
database_cross_reference: url:https://medlineplus.gov/ency/article/000005.htm

hemic and immune system symptom
type: Class
subclass of: symptom
has_obo_namespace: symptoms
id: SYMP:0017795

immune system symptom
type: Class
subclass of: hemic and immune system symptom
has_obo_namespace: symptoms
id: SYMP:0019138

hemic system symptom
type: Class
subclass of: hemic and immune system symptom
has_obo_namespace: symptoms
id: SYMP:0019139

hematopoietic system symptom
type: Class
subclass of: hemic and immune system symptom
has_obo_namespace: symptoms
id: SYMP:0019140

lymphatic system symptom
type: Class
subclass of: immune system symptom
has_obo_namespace: symptoms
id: SYMP:0019141

lymphadenopathy
type: Class
subclass of: enlargement of lymph nodes
has_exact_synonym: adenopathy
has_obo_namespace: symptoms
id: SYMP:0019142

coagulopathy
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019143

microangiopathy
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019144

vomiting
type: Class
subclass of: digestive system symptom
definition: Vomiting is a digestive system symptom characterized by throwing up the stomach contents.
has_exact_synonym: emesis
has_obo_namespace: symptoms
id: SYMP:0019145

Axiom
annotated source: vomiting
annotated property: definition
annotated target: Vomiting is a digestive system symptom characterized by throwing up the stomach contents.
database_cross_reference: url:http://www.merriam-webster.com/dictionary/vomiting

hyponatremia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019146

hematemesis
type: Class
subclass of: vomiting
definition: A vomiting where there is vomiting of blood.
has_exact_synonym: bloody vomit
has_exact_synonym: haematemesis
has_exact_synonym: vomiting blood
has_obo_namespace: symptoms
id: SYMP:0019147

Axiom
annotated source: hematemesis
annotated property: definition
annotated target: A vomiting where there is vomiting of blood.
database_cross_reference: url:http://en.wikipedia.org/wiki/Hematemesis

septicemia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019148

toxemia
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019149

obsolete pharyngitis
type: Class
term replaced by: pharynx inflammation
has_exact_synonym: pharynx inflammation
has_obo_namespace: symptoms
id: SYMP:0019150
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

pulmonary edema
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by an abnormal accumulation of fluid in the lungs.
has_exact_synonym: oedematous lungs
has_obo_namespace: symptoms
id: SYMP:0019151
comment: doid/symp duplicate

Axiom
annotated source: pulmonary edema
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by an abnormal accumulation of fluid in the lungs.

diaphoresis
type: Class
subclass of: sweaty
definition: A sweat that is characterized by excessive sweating commonly associated with shock and other medical emergency conditions.
has_exact_synonym: profuse perspiration
has_obo_namespace: symptoms
id: SYMP:0019152

Axiom
annotated source: diaphoresis
annotated property: definition
annotated target: A sweat that is characterized by excessive sweating commonly associated with shock and other medical emergency conditions.
database_cross_reference: url:http://en.wikipedia.org/wiki/Diaphoresis

dyspnea
type: Class
subclass of: respiratory abnormality
definition: A respiratory abnormality that is characterized by difficult or labored respiration.
has_exact_synonym: breathing difficulty
has_exact_synonym: breathlessness
has_exact_synonym: difficulty breathing
has_exact_synonym: labored respiration
has_exact_synonym: shortness of breath
has_obo_namespace: symptoms
id: SYMP:0019153

Axiom
annotated source: dyspnea
annotated property: definition
annotated target: A respiratory abnormality that is characterized by difficult or labored respiration.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=dyspnea

hemorrhagic mediastinitis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory abnormality that is characterized by inflammation of the mediastinum (the chest cavity, which contains the heart, the thymus gland, some lymph nodes, and parts of the esophagus, aorta, thyroid, and parathyroid glands) as the result of bleeding.
has_obo_namespace: symptoms
id: SYMP:0019154

Axiom
annotated source: hemorrhagic mediastinitis
annotated property: definition
annotated target: A respiratory abnormality that is characterized by inflammation of the mediastinum (the chest cavity, which contains the heart, the thymus gland, some lymph nodes, and parts of the esophagus, aorta, thyroid, and parathyroid glands) as the result of bleeding.
database_cross_reference: url:https://www.merckmanuals.com/home/lung-and-airway-disorders/pleural-and-mediastinal-disorders/mediastinitis

lymphadenitis
type: Class
subclass of: lymphatic system symptom
has_obo_namespace: symptoms
id: SYMP:0019155
comment: doid/symp duplicate

hematogenous
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0019156

eschar
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a scab formed especially after a burn.
has_obo_namespace: symptoms
id: SYMP:0019158

Axiom
annotated source: eschar
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a scab formed especially after a burn.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=eschar

gastroenteritis
type: Class
subclass of: digestive system symptom
has_obo_namespace: symptoms
id: SYMP:0019159
comment: doid/symp duplicate

boil
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a localized swelling and inflammation of the skin resulting from usually bacterial infection of a hair follicle and adjacent tissue, having a hard central core, and forming pus.
has_exact_synonym: furuncle
has_obo_namespace: symptoms
id: SYMP:0019160

Axiom
annotated source: boil
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a localized swelling and inflammation of the skin resulting from usually bacterial infection of a hair follicle and adjacent tissue, having a hard central core, and forming pus.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=boil

muscle pain
type: Class
subclass of: pain
definition: A pain that is characterized by a pain in one or more muscles.
has_alternative_id: SYMP:0000626
has_exact_synonym: myalgia
has_obo_namespace: symptoms
id: SYMP:0019161

Axiom
annotated source: muscle pain
annotated property: definition
annotated target: A pain that is characterized by a pain in one or more muscles.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=myalgia

muscle tightness
type: Class
subclass of: muscle symptom
has_obo_namespace: symptoms
id: SYMP:0019162

eye symptom
type: Class
subclass of: head symptom
has_obo_namespace: symptoms
id: SYMP:0019163

excessive tearing
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0019164
comment: doid/symp duplicate

light sensitivity
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0019165

obsolete ulcerations
type: Class
has_exact_synonym: ulcer
has_exact_synonym: ulcers
has_obo_namespace: symptoms
id: SYMP:0019166
deprecated: true

pustule
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by a small circumscribed elevation of the skin containing pus and having an inflamed base.
has_obo_namespace: symptoms
id: SYMP:0019167

Axiom
annotated source: pustule
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by a small circumscribed elevation of the skin containing pus and having an inflamed base.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=pustule

obsolete pneumonia
type: Class
definition: A pneumonitis that is characterized by an inflammatory illness of the lung resulting from a variety of causes including infection with bacteria, viruses, fungi, or parasites, and chemical or physical injury to the lungs. Its cause may also be officially described as idiopathic, that is, unknown, when infectious causes have been excluded.
has_obo_namespace: symptoms
id: SYMP:0019168
comment: doid/symp duplicate - reviewed 10/2022 & determined to be a disease
deprecated: true

Axiom
annotated source: obsolete pneumonia
annotated property: definition
annotated target: A pneumonitis that is characterized by an inflammatory illness of the lung resulting from a variety of causes including infection with bacteria, viruses, fungi, or parasites, and chemical or physical injury to the lungs. Its cause may also be officially described as idiopathic, that is, unknown, when infectious causes have been excluded.
database_cross_reference: url:http://en.wikipedia.org/wiki/Pneumonia

arthritis
type: Class
subclass of: musculoskeletal system symptom
definition: Arthritis is a musculoskeletal system symptom characterized as an inflammation of joints due to infectious, metabolic, or constitutional causes.
has_obo_namespace: symptoms
id: SYMP:0019169
comment: doid/symp duplicate

Axiom
annotated source: arthritis
annotated property: definition
annotated target: Arthritis is a musculoskeletal system symptom characterized as an inflammation of joints due to infectious, metabolic, or constitutional causes.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=arthritis

obsolete osteomyelitis
type: Class
has_obo_namespace: symptoms
id: SYMP:0019170
deprecated: true

spondylitis
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an inflammation of the vertebrae.
has_obo_namespace: symptoms
id: SYMP:0019171
comment: doid/symp duplicate

Axiom
annotated source: spondylitis
annotated property: definition
annotated target: A nervous system symptom that is characterized by an inflammation of the vertebrae.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=spondylitis

ocular lesion
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0019172

meningitis
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an inflammation of the meninges and especially of the pia mater and the arachnoid.
has_obo_namespace: symptoms
id: SYMP:0019173

Axiom
annotated source: meningitis
annotated property: definition
annotated target: A nervous system symptom that is characterized by an inflammation of the meninges and especially of the pia mater and the arachnoid.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=meningitis

chills
type: Class
subclass of: general symptom
has_exact_synonym: rigors
has_obo_namespace: symptoms
id: SYMP:0019174

sweaty
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by the excretion of moisture in visible quantities through the opening of the sweat glands.
has_exact_synonym: perspire
has_obo_namespace: symptoms
id: SYMP:0019175

Axiom
annotated source: sweaty
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by the excretion of moisture in visible quantities through the opening of the sweat glands.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=sweat

malaise
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by an indefinite feeling of debility or lack of health, often indicative of or accompanying the onset of an illness.
has_obo_namespace: symptoms
id: SYMP:0019176

Axiom
annotated source: malaise
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by an indefinite feeling of debility or lack of health, often indicative of or accompanying the onset of an illness.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=malaise

fatigue
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a weariness or exhaustion from labor, exertion, or stress.
has_obo_namespace: symptoms
id: SYMP:0019177

Axiom
annotated source: fatigue
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a weariness or exhaustion from labor, exertion, or stress.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=fatigue

necrotic lesion
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by regions of cell death to living tissue in an organ, which has suffered damage through injury or disease, such as a wound, ulcer, abscess, or tumor.
has_obo_namespace: symptoms
id: SYMP:0019178

Axiom
annotated source: necrotic lesion
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by regions of cell death to living tissue in an organ, which has suffered damage through injury or disease, such as a wound, ulcer, abscess, or tumor.
database_cross_reference: url:https://en.wikipedia.org/wiki/Lesion
database_cross_reference: url:https://en.wikipedia.org/wiki/Necrosis

lightheadedness
type: Class
subclass of: balance symptom
definition: A balance symptom that is characterized by a condition of being dizzy or on the verge of fainting, particularly when one arises to a standing position. Lightheadedness is a predictable consequence of any medication tending to lower blood pressure.
has_exact_synonym: light-headedness
has_obo_namespace: symptoms
id: SYMP:0019179

Axiom
annotated source: lightheadedness
annotated property: definition
annotated target: A balance symptom that is characterized by a condition of being dizzy or on the verge of fainting, particularly when one arises to a standing position. Lightheadedness is a predictable consequence of any medication tending to lower blood pressure.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=light-headedness

constipation
type: Class
subclass of: feces and droppings symptom
definition: Constipation is a feces and droppings symptom involving the abnormally delayed or infrequent passage of dry hardened feces. Constipation may be categorized into three subtypes: normal-transit, slow-transit, and pelvic floor dysfunction.
has_obo_namespace: symptoms
id: SYMP:0019180
comment: doid/symp duplicate

Axiom
annotated source: constipation
annotated property: definition
annotated target: Constipation is a feces and droppings symptom involving the abnormally delayed or infrequent passage of dry hardened feces. Constipation may be categorized into three subtypes: normal-transit, slow-transit, and pelvic floor dysfunction.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=constipation
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170709/

hoarseness
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0019181

behavioral symptom
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by an involvement, or relation to, or emphasizes behavior.
has_obo_namespace: symptoms
id: SYMP:0019182

Axiom
annotated source: behavioral symptom
annotated property: definition
annotated target: A nervous system symptom that is characterized by an involvement, or relation to, or emphasizes behavior.
database_cross_reference: url:http://dictionary.cambridge.org/dictionary/english/behavioural

hyperactivity
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by an increase in movement, impulsive actions, a shorter attention span, and being easily distracted.
has_obo_namespace: symptoms
id: SYMP:0019183

Axiom
annotated source: hyperactivity
annotated property: definition
annotated target: A behavioral symptom that is characterized by an increase in movement, impulsive actions, a shorter attention span, and being easily distracted.
database_cross_reference: url:https://medlineplus.gov/ency/article/003256.htm

limited attention
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by a restricted rate of information processing by the brain.
has_obo_namespace: symptoms
id: SYMP:0019184

Axiom
annotated source: limited attention
annotated property: definition
annotated target: A behavioral symptom that is characterized by a restricted rate of information processing by the brain.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pubmed/15084813

communication difficulty
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by speech, language and communication needs or communication disabilities.
has_obo_namespace: symptoms
id: SYMP:0019185

Axiom
annotated source: communication difficulty
annotated property: definition
annotated target: A behavioral symptom that is characterized by speech, language and communication needs or communication disabilities.
database_cross_reference: url:http://www.mhldcc.org.uk/contents/6-communication-difficulties/a-what-are-communication-difficulties.aspx

obsessive interests
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by obsessive and highly-focused interests.
has_obo_namespace: symptoms
id: SYMP:0019186

Axiom
annotated source: obsessive interests
annotated property: definition
annotated target: A behavioral symptom that is characterized by obsessive and highly-focused interests.
database_cross_reference: url:http://www.autism.org.uk/about/behaviour/obsessions-repetitive-routines.aspx
database_cross_reference: url:https://en.wikipedia.org/wiki/Perseveration

repetitive behavior
type: Class
subclass of: behavioral symptom
definition: A behavioral symptom that is characterized by an unusual repetitive motor movements or manipulation of objects.
has_exact_synonym: stimming
has_obo_namespace: symptoms
id: SYMP:0019187

Axiom
annotated source: repetitive behavior
annotated property: definition
annotated target: A behavioral symptom that is characterized by an unusual repetitive motor movements or manipulation of objects.
database_cross_reference: url:http://www.autism.org.uk/about/behaviour/obsessions-repetitive-routines.aspx##repetitive

intracranial hemorrhage
type: Class
subclass of: hemorrhage
definition: A hemorrhage that is characterized by any bleeding occurring within the skull.
has_obo_namespace: symptoms
id: SYMP:0019188

Axiom
annotated source: intracranial hemorrhage
annotated property: definition
annotated target: A hemorrhage that is characterized by any bleeding occurring within the skull.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK542273/

intracerebral hemorrhage
type: Class
subclass of: hemorrhage
definition: A hemorrhage that is characterized by bleeding within the brain tissue itself.
has_obo_namespace: symptoms
id: SYMP:0019189

Axiom
annotated source: intracerebral hemorrhage
annotated property: definition
annotated target: A hemorrhage that is characterized by bleeding within the brain tissue itself.
database_cross_reference: url:https://mayfieldclinic.com/pe-ich.htm

subdural hemorrhage
type: Class
subclass of: hemorrhage
definition: A hemorrhage that is characterized by bleeding that occurs within the skull of head but outside the actual brain tissue.
has_exact_synonym: subdural hematoma
has_obo_namespace: symptoms
id: SYMP:0019190

Axiom
annotated source: subdural hemorrhage
annotated property: definition
annotated target: A hemorrhage that is characterized by bleeding that occurs within the skull of head but outside the actual brain tissue.
database_cross_reference: url:https://my.clevelandclinic.org/health/diseases/21183-subdural-hematoma

airway stenosis
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by a narrowing in the airway that obstructs the passage of air into the lungs. Examples include tracheal and laryngotracheal stenosis.
has_obo_namespace: symptoms
id: SYMP:0020000

Axiom
annotated source: airway stenosis
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by a narrowing in the airway that obstructs the passage of air into the lungs. Examples include tracheal and laryngotracheal stenosis.
database_cross_reference: url:https://throatdisorder.com/breathing-disorders/tracheal-stenosis/
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK554561/

apthous ulcer
type: Class
subclass of: skin ulcer
definition: A skin ulcer that is characterized by a small recurrent, painful, round or ovoid ulcers with well-defined erythematous margins, like a halo, and a central yellow or gray floor found in the soft tissue of the oral cavity.
has_exact_synonym: aphthous stomatitis
has_exact_synonym: canker sore
has_obo_namespace: symptoms
id: SYMP:0020001

Axiom
annotated source: apthous ulcer
annotated property: definition
annotated target: A skin ulcer that is characterized by a small recurrent, painful, round or ovoid ulcers with well-defined erythematous margins, like a halo, and a central yellow or gray floor found in the soft tissue of the oral cavity.
database_cross_reference: url:https://en.wikipedia.org/wiki/Aphthous_stomatitis

anal abscess
type: Class
subclass of: abscess
has_obo_namespace: symptoms
id: SYMP:0020002

acholic stool
type: Class
subclass of: feces and droppings symptom
has_exact_synonym: clay-colored bowel movement
has_obo_namespace: symptoms
id: SYMP:0020003

ageusia
type: Class
subclass of: disturbances of sensation of smell and taste
definition: A disturbances of sensation of smell and taste that is characterized by a complete loss of taste function of the tongue.
has_exact_synonym: loss of taste
has_obo_namespace: symptoms
id: SYMP:0020004

Axiom
annotated source: ageusia
annotated property: definition
annotated target: A disturbances of sensation of smell and taste that is characterized by a complete loss of taste function of the tongue.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK549775/

acquired color vision deficiency
type: Class
subclass of: vision symptom
has_obo_namespace: symptoms
id: SYMP:0020005

agitation
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by a feeling of irritability or severe restlessness.
has_obo_namespace: symptoms
id: SYMP:0020006

Axiom
annotated source: agitation
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by a feeling of irritability or severe restlessness.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK493153/

anterior scleral inflammation
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0020007

barking croup cough
type: Class
subclass of: cough
definition: A cough that is characterized by a tight, low-pitched, and barky (like a barking seal) cough.
has_obo_namespace: symptoms
id: SYMP:0020008

Axiom
annotated source: barking croup cough
annotated property: definition
annotated target: A cough that is characterized by a tight, low-pitched, and barky (like a barking seal) cough.
database_cross_reference: url:https://www.seattlechildrens.org/conditions/a-z/croup/

blind spot
type: Class
subclass of: vision symptom
has_obo_namespace: symptoms
id: SYMP:0020009

blurred vision with haloes
type: Class
subclass of: blurred vision
has_obo_namespace: symptoms
id: SYMP:0020010

bloody diarrhea
type: Class
subclass of: diarrhea
has_obo_namespace: symptoms
id: SYMP:0020011

weight symptom
type: Class
subclass of: nutrition, metabolism, and development symptom
has_obo_namespace: symptoms
id: SYMP:0020012

abnormal weight loss
type: Class
subclass of: weight loss
definition: A weight loss that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying.
has_obo_namespace: symptoms
id: SYMP:0020013

Axiom
annotated source: abnormal weight loss
annotated property: definition
annotated target: A weight loss that is characterized as deviating from what is normal or usual, typically in a way that is undesirable or worrying.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/abnormal

chronic weight loss
type: Class
subclass of: weight loss
definition: A weight loss that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both.
has_obo_namespace: symptoms
id: SYMP:0020014

Axiom
annotated source: chronic weight loss
annotated property: definition
annotated target: A weight loss that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both.
database_cross_reference: url:https://www.cdc.gov/chronicdisease/about/index.htm#

obsolete gain of weight
type: Class
term replaced by: weight gain
has_alternative_id: SYMP:0000403
has_exact_synonym: weight gain
has_obo_namespace: symptoms
id: SYMP:0020015
comment: false
deprecated: true

acute weight gain
type: Class
subclass of: weight gain
definition: A weight gain that is characterized by a severe and sudden onset.
has_obo_namespace: symptoms
id: SYMP:0020016

Axiom
annotated source: acute weight gain
annotated property: definition
annotated target: A weight gain that is characterized by a severe and sudden onset.
database_cross_reference: url:https://medlineplus.gov/ency/imagepages/18126.htm

chronic weight gain
type: Class
subclass of: weight gain
definition: A weight gain that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both.
has_obo_namespace: symptoms
id: SYMP:0020017

Axiom
annotated source: chronic weight gain
annotated property: definition
annotated target: A weight gain that is characterized by conditions that last 1 year or more and require ongoing medical attention, or limit activities of daily living, or both.
database_cross_reference: url:https://www.cdc.gov/chronicdisease/about/index.htm#

overweight
type: Class
subclass of: weight symptom
definition: A weight symptom that is characterized by being too heavy for one’s height. Excess body weight can come from fat, muscle, bone, and/or water retention. Being overweight does not always mean being obese.
has_exact_synonym: obesity
has_obo_namespace: symptoms
id: SYMP:0020018

Axiom
annotated source: overweight
annotated property: definition
annotated target: A weight symptom that is characterized by being too heavy for one’s height. Excess body weight can come from fat, muscle, bone, and/or water retention. Being overweight does not always mean being obese.
database_cross_reference: url:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/overweight

postnasal drainage
type: Class
subclass of: nose symptom
definition: A nose symptom that is characterized by an an excessive secretion of mucous down the back of the throat.
has_obo_namespace: symptoms
id: SYMP:0020019

abnormal scar formation
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0020020

abnormal wound healing
type: Class
subclass of: skin lesion
has_obo_namespace: symptoms
id: SYMP:0020021

bone conduction hyperacusis
type: Class
subclass of: ear symptom
definition: An ear symptom - need proper definition - placeholder for xref.
has_obo_namespace: symptoms
id: SYMP:0020022

Axiom
annotated source: bone conduction hyperacusis
annotated property: definition
annotated target: An ear symptom - need proper definition - placeholder for xref.

bone pain
type: Class
subclass of: pain
has_obo_namespace: symptoms
id: SYMP:0020023

bronchospasm
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by constriction of the air passages of the lung (as in asthma) by spasmodic contraction of the bronchial muscles.
has_obo_namespace: symptoms
id: SYMP:0020024

Axiom
annotated source: bronchospasm
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by constriction of the air passages of the lung (as in asthma) by spasmodic contraction of the bronchial muscles.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/bronchospasm

caseation
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by necrosis of tissue with conversion of damaged tissue into a soft cheesy substance.
has_obo_namespace: symptoms
id: SYMP:0020025

Axiom
annotated source: caseation
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by necrosis of tissue with conversion of damaged tissue into a soft cheesy substance.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/caseation

chronic inflammation
type: Class
subclass of: inflammation
has_obo_namespace: symptoms
id: SYMP:0020026

wet cough
type: Class
subclass of: cough
definition: A cough that is characterized by a production and expectoration (bringing up) of mucus (phlegm) or sputum.
has_exact_synonym: productive cough
has_obo_namespace: symptoms
id: SYMP:0020027

Axiom
annotated source: wet cough
annotated property: definition
annotated target: A cough that is characterized by a production and expectoration (bringing up) of mucus (phlegm) or sputum.
database_cross_reference: url:https://www.webmd.com/lung/productive-cough-causes

poor wound healing
type: Class
subclass of: skin lesion
has_obo_namespace: symptoms
id: SYMP:0020028

concentration difficulty
type: Class
subclass of: alteration of consciousness
definition: An alteration of consciousness that is characterized by a decreased ability to focus one's thoughts on something. Concentration difficulties can be related to difficulty staying awake, impulsiveness, intrusive thoughts or concerns, overactivity, or inattention. They can be caused by medical, cognitive or psychological problems, or, may be related to sleep disorders, medications, alcohol, or drugs.
has_obo_namespace: symptoms
id: SYMP:0020029

Axiom
annotated source: concentration difficulty
annotated property: definition
annotated target: An alteration of consciousness that is characterized by a decreased ability to focus one's thoughts on something. Concentration difficulties can be related to difficulty staying awake, impulsiveness, intrusive thoughts or concerns, overactivity, or inattention. They can be caused by medical, cognitive or psychological problems, or, may be related to sleep disorders, medications, alcohol, or drugs.
database_cross_reference: url:https://www.healthgrades.com/right-care/symptoms-and-conditions/concentration-difficulty

patches of hair loss with a black dot pattern
type: Class
subclass of: hair loss
definition: A hair symptom that is characterized by patchy hair loss and the presence of comedo-like cadaver hairs, which appear as black dots.
has_obo_namespace: symptoms
id: SYMP:0020030

Axiom
annotated source: patches of hair loss with a black dot pattern
annotated property: definition
annotated target: A hair symptom that is characterized by patchy hair loss and the presence of comedo-like cadaver hairs, which appear as black dots.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148295/

chest discomfort
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by pain, pressure, tightness, or other discomfort originating in or radiating to the chest, which constitutes an important indicator of potentially serious cardiac or cardiovascular disorders.
has_obo_namespace: symptoms
id: SYMP:0020031

Axiom
annotated source: chest discomfort
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by pain, pressure, tightness, or other discomfort originating in or radiating to the chest, which constitutes an important indicator of potentially serious cardiac or cardiovascular disorders.
database_cross_reference: url:https://www.ncbi.nlm.nih.gov/books/NBK416/

chest tightness
type: Class
subclass of: chest discomfort
definition: A chest discomfort that is characterized by any type of pain or discomfort between your upper belly and lower neck.
has_obo_namespace: symptoms
id: SYMP:0020032

paroxysmal cough
type: Class
subclass of: cough
definition: A cough that is characterized by a persistent cough with sudden onset due to difficulty expelling thick mucus from the tracheobronchial tree. This type of cough is associated with diseases such as Pertussis (Whooping Cough).
has_obo_namespace: symptoms
id: SYMP:0020033

conjunctiva symptom
type: Class
subclass of: eye symptom
has_obo_namespace: symptoms
id: SYMP:0020034

conjunctival congestion
type: Class
subclass of: conjunctiva symptom
definition: An eye symptom that is characterized by (need def conjunctival congestion - placeholder for xref).
has_obo_namespace: symptoms
id: SYMP:0020035

Axiom
annotated source: conjunctival congestion
annotated property: definition
annotated target: An eye symptom that is characterized by (need def conjunctival congestion - placeholder for xref).
database_cross_reference: url:https://pubmed.ncbi.nlm.nih.gov/32283878/

conjunctival degeneration
type: Class
subclass of: conjunctiva symptom
has_obo_namespace: symptoms
id: SYMP:0020036

conjunctival suffusion
type: Class
subclass of: conjunctiva symptom
definition: An eye symptom that is characterized by (need def conjunctival suffusion - placeholder for xref).
has_obo_namespace: symptoms
id: SYMP:0020037

Axiom
annotated source: conjunctival suffusion
annotated property: definition
annotated target: An eye symptom that is characterized by (need def conjunctival suffusion - placeholder for xref).
database_cross_reference: url:https://en.wikipedia.org/wiki/Conjunctival_suffusion

conjunctival swelling
type: Class
subclass of: conjunctiva symptom
has_obo_namespace: symptoms
id: SYMP:0020038

contracture
type: Class
subclass of: musculoskeletal system symptom
definition: A musculoskeletal system symptom that is characterized by a permanent tightening of the muscles, tendons, skin, and nearby tissues that causes the joints to shorten and become very stiff.
has_obo_namespace: symptoms
id: SYMP:0020039

Axiom
annotated source: contracture
annotated property: definition
annotated target: A musculoskeletal system symptom that is characterized by a permanent tightening of the muscles, tendons, skin, and nearby tissues that causes the joints to shorten and become very stiff.
database_cross_reference: url:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/contracture

hair symptom
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0020040

corkscrew hair
type: Class
subclass of: hair symptom
definition: A hair symptom that is characterized by coiled “corkscrew” hairs on the surface of the arms, legs and chest, which can occur as a result low level of ascorbic acid (vitamin C).
has_obo_namespace: symptoms
id: SYMP:0020041

Axiom
annotated source: corkscrew hair
annotated property: definition
annotated target: A hair symptom that is characterized by coiled “corkscrew” hairs on the surface of the arms, legs and chest, which can occur as a result low level of ascorbic acid (vitamin C).
database_cross_reference: url:https://medlineplus.gov/ency/imagepages/2345.htm
database_cross_reference: url:https://www.ccjm.org/content/ccjom/82/4/216.full.pdf
database_cross_reference: url:https://www.miningjournal.net/life/tuesday-health/2021/09/urology-pearls-the-mystery-of-the-corkscrew-hair-part-2/

corneal scarring
type: Class
subclass of: cornea symptom
definition: A cornea symptom that is characterized by scarring (an opacity or irregularity in the cornea) of the cornea, from trauma; abrasion; bacterial, fungal, viral, or parasitic infection; or disease, and can result in impaired vision, or even blindness.
has_obo_namespace: symptoms
id: SYMP:0020042

Axiom
annotated source: corneal scarring
annotated property: definition
annotated target: A cornea symptom that is characterized by scarring (an opacity or irregularity in the cornea) of the cornea, from trauma; abrasion; bacterial, fungal, viral, or parasitic infection; or disease, and can result in impaired vision, or even blindness.
database_cross_reference: url:https://drstuartterry.com/eye-conditions/corneal-scarring/
database_cross_reference: url:https://www.neohioeyes.com/cornea-center/corneal-scar/

dark urine
type: Class
subclass of: urinary system symptom
definition: A urinary system symptom that is characterized by an elevation in the concentration of the the pigments from foods, dyes, and medications in urine. The dilution of these pigment is dependent on the amount of water intake and severe dehydration can lead to a dark color.
has_obo_namespace: symptoms
id: SYMP:0020043

Axiom
annotated source: dark urine
annotated property: definition
annotated target: A urinary system symptom that is characterized by an elevation in the concentration of the the pigments from foods, dyes, and medications in urine. The dilution of these pigment is dependent on the amount of water intake and severe dehydration can lead to a dark color.
database_cross_reference: url:https://www.mayoclinic.org/diseases-conditions/urine-color/symptoms-causes/syc-20367333

hair shedding
type: Class
subclass of: hair symptom
definition: A hair symptom that is characterized by significant falling out of hair, which may be a result of stress, high fever, and other factors.
has_obo_namespace: symptoms
id: SYMP:0020044

Axiom
annotated source: hair shedding
annotated property: definition
annotated target: A hair symptom that is characterized by significant falling out of hair, which may be a result of stress, high fever, and other factors.
database_cross_reference: url:https://www.aad.org/public/diseases/hair-loss/insider/shedding

balance symptom
type: Class
subclass of: neurological and physiological symptom
definition: A neurological and physiological symptom that is characterized by any of the following: dizziness or vertigo (a spinning sensation); falling or feeling as if you are going to fall; staggering when walking; lightheadedness, faintness, or a floating sensation; and confusion or disorientation.
has_obo_namespace: symptoms
id: SYMP:0020045

Axiom
annotated source: balance symptom
annotated property: definition
annotated target: A neurological and physiological symptom that is characterized by any of the following: dizziness or vertigo (a spinning sensation); falling or feeling as if you are going to fall; staggering when walking; lightheadedness, faintness, or a floating sensation; and confusion or disorientation.
database_cross_reference: url:https://www.nidcd.nih.gov/health/balance-disorders

feeding problem
type: Class
subclass of: feeding difficulties and mismanagement
definition: A feeding difficulties and mismanagement that is characterized by delays and/or disorders in the development of eating and drinking skills including disordered placement of food in the mouth, difficulty in appropriately manipulating food when it is in the mouth, difficulty chewing, and/or difficulty swallowing.
has_obo_namespace: symptoms
id: SYMP:0020046

Axiom
annotated source: feeding problem
annotated property: definition
annotated target: A feeding difficulties and mismanagement that is characterized by delays and/or disorders in the development of eating and drinking skills including disordered placement of food in the mouth, difficulty in appropriately manipulating food when it is in the mouth, difficulty chewing, and/or difficulty swallowing.
database_cross_reference: url:https://link.springer.com/referenceworkentry/10.1007/978-1-4419-1698-3_1666

descending muscle paralysis
type: Class
subclass of: paralysis
definition: A paralysis that is characterized by a loss of motor function in one or more muscles, which can also be accompanied by a loss of feeling (sensory loss). Descending paralysis contrasts with ascending paralysis in that descending paralysis presents in the upper limbs before the lower limbs. Descending paralysis occurs in conditions such as botulism.
has_obo_namespace: symptoms
id: SYMP:0020047

Axiom
annotated source: descending muscle paralysis
annotated property: definition
annotated target: A paralysis that is characterized by a loss of motor function in one or more muscles, which can also be accompanied by a loss of feeling (sensory loss). Descending paralysis contrasts with ascending paralysis in that descending paralysis presents in the upper limbs before the lower limbs. Descending paralysis occurs in conditions such as botulism.
database_cross_reference: url:https://en.wikipedia.org/wiki/Paralysis

skin peeling
type: Class
subclass of: skin and integumentary tissue symptom
has_obo_namespace: symptoms
id: SYMP:0020048

delayed psychomotor development
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by the delay in development child's cognitive, emotional, motor, and social capacities from the beginning of life throughout fetal and neonatal periods, infancy, childhood, and adolescence.
has_obo_namespace: symptoms
id: SYMP:0020049

Axiom
annotated source: delayed psychomotor development
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by the delay in development child's cognitive, emotional, motor, and social capacities from the beginning of life throughout fetal and neonatal periods, infancy, childhood, and adolescence.
database_cross_reference: url:https://pubmed.ncbi.nlm.nih.gov/23622146/
database_cross_reference: url:https://www.webmd.com/parenting/baby/recognizing-developmental-delays-birth-age-2

decreased tearing
type: Class
subclass of: eye symptom
definition: An eye symptom that is characterized by a reduction in the saline fluid secreted by the lacrimal gland.
has_obo_namespace: symptoms
id: SYMP:0020050

Axiom
annotated source: decreased tearing
annotated property: definition
annotated target: An eye symptom that is characterized by a reduction in the saline fluid secreted by the lacrimal gland.
database_cross_reference: url:https://www.merriam-webster.com/dictionary/tear

decreased metabolism
type: Class
subclass of: nutrition, metabolism, and development symptom
definition: A nutrition, metabolism, and development symptom that is characterized by a reduction in the chemical reactions catalyzed by enzymes, which keep us alive. Metabolism allows organisms to grow, reproduce, maintain their structures, and respond to their environments and can be divided into catabolism (breaking down of organic matter) and anabolism (building of molecules).
has_obo_namespace: symptoms
id: SYMP:0020051

Axiom
annotated source: decreased metabolism
annotated property: definition
annotated target: A nutrition, metabolism, and development symptom that is characterized by a reduction in the chemical reactions catalyzed by enzymes, which keep us alive. Metabolism allows organisms to grow, reproduce, maintain their structures, and respond to their environments and can be divided into catabolism (breaking down of organic matter) and anabolism (building of molecules).
database_cross_reference: url:https://simple.wikipedia.org/wiki/Metabolism

hand weakness
type: Class
subclass of: muscle weakness
definition: A muscle weakness that is characterized by a reduction in muscle strength, which may be the result of a variety of conditions, such as carpal tunnel syndrome, arthritis, peripheral neuropathy, tendon damage, and ganglion cysts.
has_obo_namespace: symptoms
id: SYMP:0020052

Axiom
annotated source: hand weakness
annotated property: definition
annotated target: A muscle weakness that is characterized by a reduction in muscle strength, which may be the result of a variety of conditions, such as carpal tunnel syndrome, arthritis, peripheral neuropathy, tendon damage, and ganglion cysts.
database_cross_reference: url:https://www.buoyhealth.com/learn/hand-weakness
database_cross_reference: url:https://www.medicalnewstoday.com/articles/hand-weakness

mammary gland inflammation
type: Class
subclass of: skin and integumentary tissue symptom
definition: A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection.
has_exact_synonym: inflammation of mammary breast
has_exact_synonym: mammitis
has_obo_namespace: symptoms
id: SYMP:0020053

Axiom
annotated source: mammary gland inflammation
annotated property: definition
annotated target: A skin and integumentary tissue symptom that is characterized by an inflammation of the mammary gland or udder and usually caused by infection.
database_cross_reference: url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=mastitis

severe mammary gland inflammation
type: Class
subclass of: mammary gland inflammation
definition: A mammary gland inflammation that is characterized by an increased intensity or severity of the condition.
has_obo_namespace: symptoms
id: SYMP:0020054

Axiom
annotated source: severe mammary gland inflammation
annotated property: definition
annotated target: A mammary gland inflammation that is characterized by an increased intensity or severity of the condition.
database_cross_reference: url:https://medical-dictionary.thefreedictionary.com/severe

pharynx inflammation
type: Class
subclass of: throat symptom
has_obo_namespace: symptoms
id: SYMP:0020055

cerebrovascular accident
type: Class
subclass of: nervous system symptom
definition: A nervous system symptom that is characterized by a loss of blood flow to part of the brain, which damages brain tissue. Cerebrovascular accidents are caused by blood clots and broken blood vessels in the brain.
has_exact_synonym: apoplexy
has_exact_synonym: cerebral accident
has_exact_synonym: cerebral hemorrhage
has_obo_namespace: symptoms
id: SYMP:0020056

Axiom
annotated source: cerebrovascular accident
annotated property: definition
annotated target: A nervous system symptom that is characterized by a loss of blood flow to part of the brain, which damages brain tissue. Cerebrovascular accidents are caused by blood clots and broken blood vessels in the brain.
database_cross_reference: url:https://www.healthline.com/health/cerebrovascular-accident

bronchiole inflammation
type: Class
subclass of: respiratory system and chest symptom
definition: A respiratory system and chest symptom that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs.
has_obo_namespace: symptoms
id: SYMP:0020057

Axiom
annotated source: bronchiole inflammation
annotated property: definition
annotated target: A respiratory system and chest symptom that is characterized by acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs.
database_cross_reference: url:https://en.wikipedia.org/wiki/Bronchopneumonia

severe bronchiole inflammation
type: Class
subclass of: bronchiole inflammation
has_obo_namespace: symptoms
id: SYMP:0020058

suppurative bronchiole inflammation
type: Class
subclass of: bronchiole inflammation
has_obo_namespace: symptoms
id: SYMP:0020059

low white blood cell count
type: Class
subclass of: hemic system symptom
has_obo_namespace: symptoms
id: SYMP:0020060

outlet dysfunction constipation
type: Class
subclass of: constipation
definition: A constipation that is characterized by difficulty passing bowel movements after they reach the rectum. One experiences difficulty evacuating the stool and often has to strain or press the fingers into the vagina or in front of or into the rectum to help remove the stool. Outlet dysfunction can be caused by inappropriate or abnormal muscle contraction of the pelvic floor (called pelvic floor dyssynergia or dyssynergic defecation) which can respond to biofeedback. It may also be due to a rectocele or other structural changes in the pelvic floor that will require medical or at times, surgical treatment.
database_cross_reference: ICD10CM:K59.02
database_cross_reference: ICD9CM:564.02
database_cross_reference: UMLS_CUI:C0949134
has_obo_namespace: symptoms
id: SYMP:0020061

Axiom
annotated source: outlet dysfunction constipation
annotated property: definition
annotated target: A constipation that is characterized by difficulty passing bowel movements after they reach the rectum. One experiences difficulty evacuating the stool and often has to strain or press the fingers into the vagina or in front of or into the rectum to help remove the stool. Outlet dysfunction can be caused by inappropriate or abnormal muscle contraction of the pelvic floor (called pelvic floor dyssynergia or dyssynergic defecation) which can respond to biofeedback. It may also be due to a rectocele or other structural changes in the pelvic floor that will require medical or at times, surgical treatment.
database_cross_reference: url:https://www.med.unc.edu/ibs/wp-content/uploads/sites/450/2017/10/Constipation.pdf

soft tissue necrosis
type: Class
subclass of: musculoskeletal system symptom
definition: A musculoskeletal system symptom that is characterized by necrosis (i.e. tissue death) of soft tissue, including muscle, fat, blood vessels, nerves, tendons, and tissues that surround the bones and joints.
has_obo_namespace: symptoms
id: SYMP:0020062

Axiom
annotated source: soft tissue necrosis
annotated property: definition
annotated target: A musculoskeletal system symptom that is characterized by necrosis (i.e. tissue death) of soft tissue, including muscle, fat, blood vessels, nerves, tendons, and tissues that surround the bones and joints.
database_cross_reference: url:https://medlineplus.gov/ency/article/001443.htm
database_cross_reference: url:https://www.health.ny.gov/statistics/cancer/registry/abouts/soft_tissue.htm

blood pressure
type: Class
subclass of: general symptom
has_obo_namespace: symptoms
id: SYMP:0020063

high blood pressure
type: Class
subclass of: blood pressure
has_obo_namespace: symptoms
id: SYMP:0020064