Contributors to the GA4GH Data Use Ontology workstream are listed at https://github.com/EBISPOT/DUO/blob/master/README.md#contributions
DUO_preferred_label
A is restricted to B iff A is a consent code and B is an investigation and A may only participate in instances of a class C, of which B is an instance.
E.g. A dataset is restricted to an instance of an investigation for a specific disease or at geographical location.
A data item that is used to indicate consent permissions for datasets and/or materials, and relates to the purposes for which datasets and/or material might be removed, stored or used.
data use permission
A categorical data item indicating the primary category the consent code belongs to according to Dyke et al. 2016.
This term was depreacted as it is not used to tag datasets but instead as patterns for DUO codes capture. This is an archive specific requirement, e.g. "one code from a primary category and one or more from a second category' This is better done by Schemablocks and constraining the pattern of usage of DUO terms at each archive level.
A categorical data item indicating the secondary category the consent code belongs to according to Dyke et al. 2016.
obsolete consent code secondary category
This data use permission indicates there is no restriction on use.
20180907, Meeting Moran Melanie: This is to be thought about more carefully - what is the intent when using 'no restriction' as usually users still need to be researchers.
Note: the NRES alternative term may be confusing as in the UK it also stands for National Research Ethics Service
no restriction
This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.
population origins or ancestry research prohibited
This data use limitation indicates that use is allowed for health/medical/biomedical purposes and other biological research, including the study of population origins or ancestry.
General Research Use, DUO_0000042 Clinical Care USe, DUO_0000043
This term includes clinical care, which was not defined in the original consent codes paper. This term does not have a usage in our current use cases and we recommend using DUO:0000042, General Research Use, instead
This term was made obsolete as per https://github.com/EBISPOT/DUO/issues/45
obsolete general research use and clinical care
This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
health or medical or biomedical research
This data use permission indicates that use is allowed provided it is related to the specified disease.
This term should be coupled with a term describing a disease from an ontology to specify the disease the restriction applies to. DUO recommends MONDO be used, to provide the basis for automated evaluation. For more information see https://github.com/EBISPOT/DUO/blob/master/MONDO_Overview.md Other resources, such as the Disease Ontology, HPO, SNOMED-CT or others, can also be used. When those other resources are being used, this may require an extra mapping step to leverage automated matching algorithms.
disease specific research
This data use permission indicates that use of the data is limited to the study of population origins or ancestry.
population origins or ancestry research only
This data use modifier indicates that use is limited to studies of a certain research type.
research specific restrictions
This data use limitation indicates that use is limited to research purposes (e.g., does not include its use in clinical care).
Deprecated as GRU-CC was split into GRU and CC, so this is not applicable anymore as a qualifier of GRU-CC
obsolete research use only
This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).
no general methods research
This data use modifier indicates that use is limited to genetic studies only (i.e., studies that include genotype research alone or both genotype and phenotype research, but not phenotype research exclusively)
genetic studies only
Data use modifiers indicate additional conditions for use.
data use modifier
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
not for profit, non commercial use only
This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
publication required
This data use modifier indicates that the requestor must agree to collaboration with the primary study investigator(s).
This could be coupled with a string describing the primary study investigator(s).
collaboration required
This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.
ethics approval required
This data use modifier indicates that use is limited to within a specific geographic region.
This should be coupled with an ontology term describing the geographical location the restriction applies to.
geographical restriction
This data use modifier indicates that requestor agrees not to publish results of studies until a specific date.
publication embargo
This should be coupled with a date specified as ISO8601
publication moratorium
This data use modifier indicates that use is approved for a specific number of months.
This should be coupled with an integer value indicating the number of months.
time limit on use
This data use modifier indicates that use is limited to use by approved users.
user specific restriction
This data use modifier indicates that use is limited to use within an approved project.
project specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
institution specific restriction
This data use modifier indicates that the requestor must return derived/enriched data to the database/resource.
return to database or resource
An investigation concerning development of methods, algorithms, software or analytical tools.
This definition is a placeholder as a result of meetings at ICBO2018.
An investigation concerning a specific population group.
Should be paired with the an ontology term representing this population (e.g., xxx).
An investigation concerning ancestry or population origins.
An investigation concerning specific age categories.
An investigation concerning specific gender categories.
An investigation concerning use of data as reference or control material.
An investigation concerning health, medical, or biomedical research.
Biomedical research concerning genetics (i.e., the study of genes, genetic variations and heredity).
Biomedical research concerning drug development.
Biomedical research research concerning specific disease/s
This data use permission indicates that use is allowed for general research use for any research purpose.
This includes but is not limited to: health/medical/biomedical purposes, fundamental biology research, the study of population origins or ancestry, statistical methods and algorithms development, and social-sciences research.
general research use
This data use modifier indicates that use is allowed for clinical use and care.
Clinical Care is defined as Health care or services provided at home, in a healthcare facility or hospital. Data may be used for clinical decision making.
clinical care use
This data use modifier indicates that use of the data is limited to not-for-profit organizations.
not for profit organisation use only
This data use modifier indicates that use of the data is limited to not-for-profit use.
This indicates that data can be used by commercial organisations for research purposes, but not commercial purposes.
non-commercial use only
A disease is a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism.
A category denoting a rather broad domain or field of interest, study, application, work, data, or technology. Topics have no clearly defined borders between each other.